Publikasi Scopus 926 artikel (Per 14 Maret 2022)

Ariestine D.A., Sari N.K., Rinaldi I., Abdullah M.
57219412521;57209884078;23475122400;7103393434;
Quality of life in older survivors of non-Hodgkin's lymphoma who received chemotherapy and related factors
2021
Journal of Geriatric Oncology
12
2
326
331
Division of Geriatric Medicine, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Indonesia; Division of Geriatric Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia; National Cancer Center-Dharmais Cancer Hospital, Jakarta, Indonesia; Division of Hemato-oncolocy, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Indonesia; Division of Gastroenterohepatology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Indonesia
Ariestine, D.A., Division of Geriatric Medicine, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Indonesia, Division of Geriatric Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia; Sari, N.K., Division of Geriatric Medicine, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Indonesia, National Cancer Center-Dharmais Cancer Hospital, Jakarta, Indonesia; Rinaldi, I., Division of Hemato-oncolocy, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Indonesia; Abdullah, M., Division of Gastroenterohepatology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, dr. Cipto Mangunkusumo Hospital, Indonesia
Introduction: Cancer and its treatment have a broad impact on patients' Quality of Life (QoL). Previous researches showed that many factors in Comprehensive Geriatric Assessment (CGA) affect QoL. CGA could predict toxicity, overall survival rate and can help adjust the choice and intensity of treatment in each patient. However, there has been no research explicitly exploring factors related to the QoL in older patients with Non-Hodgkin's Lymphoma (NHL). This research aims to explore the how factors in CGA relate to the QoL in older patients with NHL. Materials and Method: The study design was cross-sectional in NHL patients aged ≥ 60 years, research was conducted in Integrated Geriatric Polyclinic and Hemato-Oncology Polyclinic of three public hospitals in Jakarta, during March–August 2019. Results: There were 62 subjects, with a median age of 66 years, 56.5% male. The result showed that most of the patients have a good QoL, based on each domain of SF-36 and EORTC QLQ-C30. In multivariate analysis, it was found that depression and frailty status were related to PCS SF-36 domain with PR 12.086 (95% CI 1.596–92.124) and PR 5.622 (95% CI 1.060–29.807), respectively. Multivariate analysis with SF-36's Mental Component Summary (MCS) showed a significant relationship with depression status with PR 24.400 (95% CI 2.961–140.539). While the results of multivariate analysis with the EORTC QLQ-C30 functional scale showed a significant relationship with the ECOG performance score with PR 171 (95% CI 8.470–3452.28). Discussions: After multivariate analysis, only frailty status, depression status and ECOG performance score have a statistically significant relationship. © 2020 Elsevier Ltd
antineoplastic agent; cyclophosphamide plus doxorubicin plus prednisolone plus rituximab plus vincristine; Abbreviated Mental Test; adult; aged; Barthel index; Barthel Index Activities of Daily Living; body mass; cancer chemotherapy; cancer survivor; clinical evaluation; comorbidity; controlled study; cross-sectional study; Cumulative Illness Rating for Geriatrics; Cumulative Illness Rating Scale; demography; diffuse large B cell lymphoma; ECOG Performance Status; European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30; female; geriatric assessment; Geriatric Depression Scale; human; Indonesia; Karnofsky Performance Status; Lawton instrumental activities of daily living scale; Letter; major clinical study; male; mental test; middle aged; Mini Nutrit
Elsevier Ltd
18794068
33008767
Letter
Q2
1032
4192