Publikasi Scopus 926 artikel (Per 14 Maret 2022)

Prasetyo M., Mongan A.E., Chozie N.A., Prihartono J., Setiawan S.I.
57192905252;57226385960;57194329830;6602605635;57195939543;
Hemosiderin deposition evaluation in hemophilic ankle joints: association between US finding and gradient-recalled echo MR imaging sequence
2021
Insights into Imaging
12
1
107
Department of Radiology, Faculty of Medicine, Universitas Indonesia – Dr. Cipto Mangunkusumo National Central General Hospital, Jl. Diponegoro No.71, Jakarta Pusat, DKI Jakarta 10430, Indonesia; Department of Pediatric, Faculty of Medicine, Universitas Indonesia – Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Departement of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia
Prasetyo, M., Department of Radiology, Faculty of Medicine, Universitas Indonesia – Dr. Cipto Mangunkusumo National Central General Hospital, Jl. Diponegoro No.71, Jakarta Pusat, DKI Jakarta 10430, Indonesia; Mongan, A.E., Department of Radiology, Faculty of Medicine, Universitas Indonesia – Dr. Cipto Mangunkusumo National Central General Hospital, Jl. Diponegoro No.71, Jakarta Pusat, DKI Jakarta 10430, Indonesia; Chozie, N.A., Department of Pediatric, Faculty of Medicine, Universitas Indonesia – Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Prihartono, J., Departement of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Setiawan, S.I., Department of Radiology, Faculty of Medicine, Universitas Indonesia – Dr. Cipto Mangunkusumo National Central General Hospital, Jl. Diponegoro No.71, Jakarta Pusat, DKI Jakarta 10430, Indonesia
Background: Repeated bleeding in hemophilic arthropathy (HA) may result in severe degenerative changes and joint destruction. The gradient-recalled echo (GRE) sequence MR is proved to be the best method to detect hemosiderin deposition. However, MR is not widely available in developing countries, including Indonesia. Some studies have proposed ultrasonography (US) as an alternative tool in evaluating hemophilic joint. However, there is still some disagreement on the ability of US to detect hemosiderin deposition. Objective: To evaluate the association between US and GRE-sequence MR imaging in detecting hemosiderin deposition in hemophilic ankle joint. Material and methods: A total of 102 sites from 17 ankle joints of 11 boys with severe hemophilia A underwent US examination using a high-frequency linear array transducer. GRE-sequence MR examination was performed in sagittal view consistent with the sites scanned by US. Both examinations were performed on the same day, but MR interpretation was performed blindly at different times. The association between US and GRE-sequences in detecting hemosiderin deposition was analyzed using McNemar’s test. Results: Statistical analysis showed a significant association (p value < 0.001) between US and GRE MR in detecting hemosiderin deposition, but the association is weak (R = 0.26). Sensitivity and specificity of US for detecting hemosiderin deposition were 46.84% (95%CI: 35.51–58.40) and 95.65% (95%CI: 78.05–99.89), respectively, with positive predictive value 97.37% (95%CI: 84.29–99.61), negative predictive value 34.38% (95%CI: 29.50–39.60) and accuracy 57.84% (95%CI: 47.66–67.56). Conclusion: There was a weak association between US and GRE-sequences in detecting hemosiderin deposition of hemophilic ankle joint. ​​ © 2021, The Author(s).
GRE MR imaging; Hemophilic arthropathy; Hemosiderin deposition; US
gadolinium; hemosiderin; accuracy; adolescent; anisotropy; Article; child; clinical article; cross-sectional study; echography; gradient recalled echo; gray matter; hemophilic arthropathy; histopathology; human; image analysis; male; medial malleolus; nuclear magnetic resonance imaging; predictive value; sensitivity and specificity; synovectomy
Springer Science and Business Media Deutschland GmbH
18694101
Article
Q1
1405
2531