Publikasi Scopus 926 artikel (Per 14 Maret 2022)

Ardinata D., Zain-Hamid R., Roesyanto-Mahadi I.D., Mihardja H.
57201518818;8059724800;57222900126;57195721818;
Interleukin-31 serum and pruritus dimension after acupuncture treatment in hemodialysis patients: A randomized clinical trial
2021
Open Access Macedonian Journal of Medical Sciences
9
B
196
201
Department of Physiology, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia; Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia; Department of Dermatology and Venereology, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia; Department of Medical Acupuncture, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia
Ardinata, D., Department of Physiology, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia; Zain-Hamid, R., Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia; Roesyanto-Mahadi, I.D., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia; Mihardja, H., Department of Medical Acupuncture, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia
BACKGROUND: Interleukin (IL)-31 serum levels were significantly higher in hemodialysis patients with pruritus, whereas acupuncture in LI11 was shown to improve symptoms of pruritus. However, there is limited information that IL-31 serum levels that correlate with decreased dimensions of the pruritus after acupuncture in LI11 in a hemodialysis patient. AIM: The aim of the study was to demonstrate the impact of acupuncture in LI11 and IL-31 serum level and its correlation with dimensions of the pruritus in hemodialysis patients. METHODS: A randomized clinical trial has been carried out from August 2019 to December 2019 at H. Adam Malik General Hospital, Medan, Indonesia. Sixty patients underwent hemodialysis who were randomly allocated to two groups, one group got acupuncture in Quchi LI11 (intervention group), and the other group got a placebo (control group). IL-31 serum levels and pruritus were measured before and after 6 weeks of acupuncture in both groups. RESULTS: Acupuncture did not significantly reduce IL-31 (p = 0.931) and decreased dimensions: Degree, duration, disability, and distribution of the pruritus between the intervention group and the control group after 6 weeks of acupuncture in LI11. It can be shown that there is no significant correlation between IL-31 serum levels and dimensions of the pruritus. CONCLUSION: This study demonstrates the effect of acupuncture on reducing dimensions of the pruritus not related to IL-31 serum levels. Identifying the action mechanism of acupuncture to minimize pruritus considerably enhances knowledge of the impacts of acupuncture on reducing pruritus in hemodialysis patients. © 2021 Dedi Ardinata, Rozaimah Zain-Hamid, Irma. D. Roesyanto-Mahadi, Hasan Mihardja.
Acupuncture; Hemodialysis; Interleukin 31; LI11 Quchi; Pruritus
bicarbonate; C reactive protein; chemical compound; hemoglobin; interleukin 31; naltrexone; polysulphane; tumor necrosis factor; unclassified drug; acupuncture; adult; Article; atopic dermatitis; body mass; controlled study; data analysis; diabetic nephropathy; disability; disease severity; enzyme linked immunosorbent assay; female; hemodialysis; hemodialysis patient; histamine release; human; hypertension; iontophoresis; kidney disease; major clinical study; male; middle aged; percutaneous coronary intervention; protein blood level; pruritus; psoriasis; quchi acupoint; questionnaire; randomized controlled trial; scoring system; urticaria; visual analog scale
Scientific Foundation SPIROSKI
18579655
Article
Q3
288
15252