Publikasi Scopus FKUI 2021 per tanggal 31 Mei 2021 (358 artikel)

Authors (Last_Name)

Dewi R., Kaswandani N., Karyanti M.R., Setyanto D.B., Pudjiadi A.H., Hendarto A., Djer M.M., Prayitno A., Yuniar I., Indawati W., Prawira Y., Handryastuti S., Sjakti H.A., Hidayati E.L., Muktiarti D., Soebadi A., Puspaningtyas N.W., Muhaimin R., Rahmadhany A., Octavius G.S., Puspitasari H.A., Jasin M.R., Tartila T., Putri N.D.

Author S Id

57190859324;57195941745;56290680800;57203009929;18435202300;57204142249;12771087900;57193342301;57222295046;57190171077;55455747000;18434003700;57195720458;57200542624;57189047743;56986580800;57223288515;57223307995;57223290366;57221016506;57214119502;57223292665;57223304533;57200573842;

Title

Mortality in children with positive SARS-CoV-2 polymerase chain reaction test: Lessons learned from a tertiary referral hospital in Indonesia

Year

2021

Source Title

International Journal of Infectious Diseases

Volume

107

Issue

Art No

Page Start

Page End

Page Count

Cited By

Link

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105478543&doi=10.1016%2fj.ijid.2021.04.019&partnerID=40&md5=6ef75a9ece8a84ed984ec94cf9c3f923

Affiliations

Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia

Authors With Affiliations

Dewi, R., Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Kaswandani, N., Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Karyanti, M.R., Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Setyanto, D.B., Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Pudjiadi, A.H., Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Hendarto, A., Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Djer, M.M., Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Prayitno, A., Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Yuniar, I., Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Indawati, W., Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Prawira, Y., Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Handryastuti, S., Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Sjakti, H.A., Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Hidayati, E.L., Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Muktiarti, D., Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Soebadi, A., Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Puspaningtyas, N.W., Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Muhaimin, R., Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Rahmadhany, A., Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Octavius, G.S., Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Puspitasari, H.A., Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Jasin, M.R., Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Tartila, T., Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Putri, N.D., Department of Paediatrics, Dr. Cipto Mangunkusumo National Central Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia

Abstract

Background: The incidence of coronavirus disease 2019 (COVID-19) is still increasing rapidly, but little is known about the prevalence and characteristics of fatal cases in children in Indonesia. This study aimed to describe the characteristics of children with COVID-19 with fatal outcomes in a tertiary referral hospital in Indonesia. Methods: This cross-sectional study used data collected from the medical records of patients with COVID-19 admitted to Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia from March to October 2020. Results: During the study period, 490 patients were admitted and diagnosed with suspected and probable COVID-19. Of these patients, 50 (10.2%) were confirmed to have COVID-19, and 20 (40%) had a fatal outcome. The fatality rate was higher in patients aged ≥10 years, categorized with severe disease upon admission, PaO2/FiO2 ratio ≤300 mmHg and chronic underlying diseases. The most common clinical manifestations were generalized symptoms, while acute respiratory distress syndrome (8/20) and septic shock (7/20) were the two most common causes of death. Increased procalcitonin, D-dimer, lactate dehydrogenase and presepsin levels were found in all fatal cases. One patient met the criteria of multisystem inflammatory syndrome in children. Conclusion: Our work highlights the high mortality rate in paediatric patients with positive SARS-CoV-2 polymerase chain reaction test. These findings might be related to or co-incided with COVID-19 infection. Further studies are needed to improve understanding of the role of severe acute respiratory syndrome coronavirus-2 in elaborating the mechanisms leading to death in children with comorbidities. © 2021 The Author(s)

Author Keywords

Children; COVID-19; Indonesia; Outcome; SARS-CoV-2

Index Keywords

antibiotic agent; biological marker; D dimer; dobutamine; dopamine; enoxaparin; epinephrine; hydrocortisone; immunoglobulin; lactate dehydrogenase; lopinavir; noradrenalin; presepsin; procalcitonin; ritonavir; steroid; unclassified drug; adolescent; adult; adult respiratory distress syndrome; age; Article; artificial ventilation; cause of death; child; childhood mortality; clinical feature; coronavirus disease 2019; cross-sectional study; disease severity; fatality; female; Horowitz index; hospital admission; human; Indonesia; infant; major clinical study; male; mortality rate; newborn; pediatric multisystem inflammatory syndrome; polymerase chain reaction; preschool child; real time polymerase chain reaction; school child; septic shock; tertiary care center

Publisher

Elsevier B.V.

Issn

12019712

Isbn

Pubmed Id

33857609

Document Type

Article

Sjr Best Quartile

Sjr

1437

Sjr Rank

2397