Publikasi Scopus FKUI 2021 per tanggal 31 Oktober 2021 (739 artikel)

Authors_(Last_Name)

Karina K., Ekaputri K., Albert Biben J., Rosadi I., Rosliana I., Sobariah S., Sulaeha A.D., Andrew H., Afini I., Widyastuti T., Jusryanti J., Prestiani S.I., Donna I.M., Mutiara M.S., Habibi H.

Author S Id

57212146678;57285088000;57284643500;57204720098;57186671400;57203547382;57226286645;57226282534;57211068324;57211074403;57284643600;57283770100;57284210300;57284210400;57222314524;

Title

Evaluation of plasma pdgf and vegf levels after systemic administration of activated autologous platelet-rich plasma

Year

2021

Source Title

Biomedicine (India)

Volume

Issue

Art No

Page Start

409

Page End

412

Page Count

Cited By

Link

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116318936&doi=10.51248%2f.v41i2.1047&partnerID=40&md5=b63a888f3eb59bb12b87fdd1bfa4f091

Affiliations

Klinik Hayandra, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Hayandra Lab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Faculty of Medicine, Universitas Pembangunan Nasional Veteran, Jakarta, 12450, Indonesia; Pusat Kajian Stem Cell, Universitas Pembangunan Nasional Veteran, Jakarta, 12450, Indonesia; Department of Biology, Faculty of Mathematics and Natural Sciences, Mulawarman University, Samarinda, 752424, Indonesia; Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no. 6, Jakarta Pusat, 10430, Indonesia

Authors With Affiliations

Karina, K., Klinik Hayandra, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia, Hayandra Lab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia, Faculty of Medicine, Universitas Pembangunan Nasional Veteran, Jakarta, 12450, Indonesia, Pusat Kajian Stem Cell, Universitas Pembangunan Nasional Veteran, Jakarta, 12450, Indonesia; Ekaputri, K., Klinik Hayandra, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Albert Biben, J., Klinik Hayandra, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Rosadi, I., Hayandra Lab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia, Department of Biology, Faculty of Mathematics and Natural Sciences, Mulawarman University, Samarinda, 752424, Indonesia; Rosliana, I., Hayandra Lab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Sobariah, S., Hayandra Lab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Sulaeha, A.D., Klinik Hayandra, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Andrew, H., Hayandra Lab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no. 6, Jakarta Pusat, 10430, Indonesia; Afini, I., Hayandra Lab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Widyastuti, T., Hayandra Lab, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Jusryanti, J., Klinik Hayandra, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Prestiani, S.I., Klinik Hayandra, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Donna, I.M., Klinik Hayandra, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Mutiara, M.S., Klinik Hayandra, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia; Habibi, H., Klinik Hayandra, Yayasan Hayandra Peduli, Jl. Kramat VI No. 11, Jakarta Pusat, 10430, Indonesia

Abstract

Introduction and Aim: Activated autologous platelet-rich plasma (aaPRP) is becoming a popular therapy to accelerate healing in the field of plastic surgery. Platelets, which are abundant in aaPRP, can release many growth factors including platelet-derived growth factor (PDGF) and vascular endothelial growth factor (VEGF). This study aims to examine the plasma levels of PDGF and VEGF in healthy subjects after intravenous administration of aaPRP. Materials and Methods: Nine healthy patients with no prior history of metabolic disease were divided into two groups (control and experiment group). The treatment group which consists of six patients received intravenous aaPRP treatment. The preparation of aaPRP starts with the collection of 24 mL of whole blood in sodium citrate tubes followed a two-step centrifugation procedure and subsequent chemical activation. aaPRP was then administered intravenously to patients. Meanwhile, the control group received no intervention. Venous blood samples were taken before and one week after the treatment and the plasma PDGF and VEGF levels were determined by enzyme-linked immunosorbent assay (ELISA). Results: The treatment group showed statistically significant increase in VEGF after 7 days compared to before aaPRP administration. However, the change in PDGF levels of the treatment group was unnotable. Conclusion: The present findings indicate that intravenous administrations of activated aaPRP may increase plasma VEGF level up to 1 week after aaPRP administration. ? 2021, Indian Association of Biomedical Scientists. All rights reserved.

Author Keywords

Activated autologous platelet-rich plasma (aaPRP); Platelet derived growth factor (PDGF); Vascular endothelial growth factor (VEGF)

Index Keywords

Publisher

Indian Association of Biomedical Scientists

Issn

9702067

Isbn

Pubmed Id

Document Type

Article

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