Publikasi Scopus FKUI Tahun 2010 s/d 2020 (data Per 3 Februari 2021)

Freisleben H.-J., Tandian D., Kuebel-Thiel K.
7003437337;57192891173;57192890227;
Application of α-lipoic acid beyond peripheral diabetic polyneuropathy (a report of 3 cases)
2011
Medical Journal of Indonesia
20
2
143
148
2
Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; RSUPN Dr. Cipto Mangukusumo, Neurosurgery Department, Jakarta, Indonesia; Egelsbacher Str. 20, Erzhausen, 64390, Germany
Freisleben, H.-J., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Tandian, D., RSUPN Dr. Cipto Mangukusumo, Neurosurgery Department, Jakarta, Indonesia; Kuebel-Thiel, K., Egelsbacher Str. 20, Erzhausen, 64390, Germany
Background: In Germany, lipoic acid is registered with the indication of “peripheral diabetic polyneuropathy”. This report intends to demonstrate therapeutic activity beyond this indication. In Indonesia, the substance is not registered for therapy. Methods: Three patients (two of them in Germany and one in Indonesia) with pathoneurological symptoms different from peripheral diabetic polyneuropathy were treated with α-lipoic acid: i) post-borelliosis inflammation with arthritic and paraesthetic symptoms, ii) post-operative (mamma carcinoma) and post-chemotherapeutic sensoric and motoric neural deficits occurring in parallel with additional radiation therapy, and iii) post-traumatic (cerebral) and postoperative (brain surgery) cardiovascular and pulmonary crisis with broad pathoneurological (sensoric and motoric, visual, auditory) deficits and dysarthria. Results: All three patients improved in close correlation with the onset and continuation of lipoic acid intake, whereas other therapeutic measures did not appear very successful. It cannot be ruled out that the other therapeutic regimens applied interacted with lipoic acid in a supporting additive or synergistic manner, because three cases as reported here do not allow for such conclusion; however, separately, or with interaction, lipoic acid helped the patients to recover from their pathoneurological symptoms in the meaning of the traditional medical term “restitutio ad integrum”. Conclusion: In the three cases in this study, lipoic acid was effective in therapy of pathoneurological symptoms different from peripheral diabetic neuropathy. Further confirmative studies are suggeted. © 2011, Faculty of Medicine, Universitas Indonesia. All rights reserved.
Cancer therapy; Cerebral trauma; Infection; Inflammation; Neuropathy; α-Lipoic acid
acetylcysteine; alpha tocopherol; calcium; carbamazepine; cyclophosphamide; doxorubicin; doxycycline; eperisone; isosorbide dinitrate; levothyroxine; paclitaxel; ranitidine; selenium; simvastatin; spironolactone; tegaserod; thioctic acid; tolterodine; vitamin D; adult; aged; Article; bacterial arthritis; Borrelia infection; brain hematoma; brain injury; breast cancer; cancer therapy; case report; central nervous system disease; computer assisted tomography; diabetic neuropathy; dysarthria; enzyme therapy; female; Hashimoto disease; human; hypothyroidism; male; middle aged; morning dosage; motor dysfunction; multiple cycle treatment; neuroprotection; nuclear magnetic resonance imaging; osteopenia; paresthesia; peripheral neuropathy; physiotherapy; pneumonia; polyneuropathy; sensory dysfunct
Faculty of Medicine, Universitas Indonesia
08531773
Article
Q3