Publikasi Scopus FKUI Tahun 2010 s/d 2020 (data Per 3 Februari 2021)

Pakasi T.A., Karyadi E., Suratih N.M.D., Salean M., Darmawidjaja N., Bor H., Van Der Velden K., Dolmans W.M., Van Der Meer J.W.
23980778600;6603080272;26634582200;35168075800;35167752900;6604019303;6603398675;7004198237;13402610900;
Zinc and vitamin A supplementation fails to reduce sputum conversion time in severely malnourished pulmonary tuberculosis patients in Indonesia
2010
Nutrition Journal
9
1
41
34
South East Asia Minister of Education Organization Tropical Medicine (SEAMEO TROPMED), Regional Center for Community Nutrition, University of Indonesia, Jl. Salemba Raya no.6, Jakarta Pusat 10420, Indonesia; Department of Community Medicine, Faculty of Medicine, University of Indonesia, Jl. Pegangsaan Timur no.16, Jakarta Pusat 10302, Indonesia; Department of General Medicine, WZ Johannes General Hospital, Jl. Mohammad Hatta no.19, Kupang, Indonesia; Department of Radiology WZ Johannes General Hospital, Jl. Mohammad Hatta no.19, Kupang, Indonesia; Kefamenanu General Hospital, North Middle Timor District (TTU), Jl. Letjend Suprapto, Kefamenanu, Indonesia; Department of Primary and Community Care, Radboud University Nijmegen Medical Center, Nijmegen International Center for Health Systems Research and Education, Geert Grooteplein Noord 21, Nijmegen 6525 EZ, Netherlands; Department of Internal Medicine, Radboud University Nijmegen Medical Center, Nijmegen Center for Infection, Inflammation and Immunity (N4I), Geert Grooteplein Zuid 8, Nijmegen 6525 GA, Netherlands; Micronutrient Initiative, Gedung Wirausaha Lt. 2 Jl. HR. Rasuna Said Kav C5, Jakarta 12920, Indonesia
Pakasi, T.A., South East Asia Minister of Education Organization Tropical Medicine (SEAMEO TROPMED), Regional Center for Community Nutrition, University of Indonesia, Jl. Salemba Raya no.6, Jakarta Pusat 10420, Indonesia, Department of Community Medicine, Faculty of Medicine, University of Indonesia, Jl. Pegangsaan Timur no.16, Jakarta Pusat 10302, Indonesia; Karyadi, E., South East Asia Minister of Education Organization Tropical Medicine (SEAMEO TROPMED), Regional Center for Community Nutrition, University of Indonesia, Jl. Salemba Raya no.6, Jakarta Pusat 10420, Indonesia, Micronutrient Initiative, Gedung Wirausaha Lt. 2 Jl. HR. Rasuna Said Kav C5, Jakarta 12920, Indonesia; Suratih, N.M.D., Department of General Medicine, WZ Johannes General Hospital, Jl. Mohammad Hatta no.19, Kupang, Indonesia; Salean, M., Department of Radiology WZ Johannes General Hospital, Jl. Mohammad Hatta no.19, Kupang, Indonesia; Darmawidjaja, N., Kefamenanu General Hospital, North Middle Timor District (TTU), Jl. Letjend Suprapto, Kefamenanu, Indonesia; Bor, H., Department of Primary and Community Care, Radboud University Nijmegen Medical Center, Nijmegen International Center for Health Systems Research and Education, Geert Grooteplein Noord 21, Nijmegen 6525 EZ, Netherlands; Van Der Velden, K., Department of Primary and Community Care, Radboud University Nijmegen Medical Center, Nijmegen International Center for Health Systems Research and Education, Geert Grooteplein Noord 21, Nijmegen 6525 EZ, Netherlands; Dolmans, W.M., Department of Internal Medicine, Radboud University Nijmegen Medical Center, Nijmegen Center for Infection, Inflammation and Immunity (N4I), Geert Grooteplein Zuid 8, Nijmegen 6525 GA, Netherlands; Van Der Meer, J.W., Department of Internal Medicine, Radboud University Nijmegen Medical Center, Nijmegen Center for Infection, Inflammation and Immunity (N4I), Geert Grooteplein Zuid 8, Nijmegen 6525 GA, Netherlands
Background. A previous study showed that combination of zinc and vitamin A reduced sputum conversion time in pulmonary tuberculosis (TB) patients. Objective. We studied the efficacy of which single micronutrient contributed more to the sputum conversion time. Methods. In a double-blind randomized community trial, newly sputum smear positive pulmonary TB patients were assigned randomly to receive zinc, vitamin A, zinc + vitamin A or placebo on top of TB treatment. Patients were asked to deliver their sputum on weekly basis to measure positivity of the bacteria. Nutritional status, chest x-ray, hemoglobin, C-reactive protein (CRP), retinol and zinc level were examined prior to, after 2 and 6 months of treatment. Results. Initially, 300 patients were enrolled, and 255 finished the treatment. Most patients were severely malnourished (mean BMI 16.5 2.2 Kg/m2). Patients in the zinc + vitamin A group showed earlier sputum conversion time (mean 1.9 weeks) compared with that in the other groups; however the difference was not significant. Also, no benefit could be demonstrated of any of the used supplementations on clinical, nutritional, chest x-ray, or laboratory findings. Conclusions. This study among severely malnourished TB patients, did not confirm that single or combined supplementation of zinc and vitamin A significantly reduced sputum conversion time or had other significant benefit. © 2010 Pakasi et al; licensee BioMed Central Ltd.
C reactive protein; ethambutol; hemoglobin; isoniazid; placebo; pyrazinamide; retinol acetate; rifampicin; zinc sulfate; retinol; tuberculostatic agent; vitamin; zinc; adolescent; adult; antibiotic therapy; article; clinical trial; community trial; controlled clinical trial; controlled study; diet supplementation; disease severity; double blind procedure; drug efficacy; female; hemoglobin blood level; human; Indonesia; lung tuberculosis; major clinical study; male; malnutrition; monotherapy; Mycobacterium tuberculosis; nonhuman; nutritional status; randomized controlled trial; retinol deficiency; sputum; sputum conversion time; sputum smear; thorax radiography; time; treatment duration; treatment response; vitamin blood level; zinc blood level; zinc deficiency; drug effect; immune system;
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