Publikasi Scopus FKUI Tahun 2010 s/d 2020 (data Per 3 Februari 2021)

Suarthana E., Vergouwe Y., Moons K.G., De Monchy J., Grobbee D., Heederik D., Meijer E.
8917676900;8917677200;7004546169;7004458730;7103100613;7006663815;7202419955;
A diagnostic model for the detection of sensitization to wheat allergens was developed and validated in bakery workers
2010
Journal of Clinical Epidemiology
63
9
1011
1019
16
Environmental Epidemiology Division, Institute for Risk Assessment Sciences (IRAS), Utrecht University, 3508 TD, Utrecht, Netherlands; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, 3508 GA, Utrecht, Netherlands; Community Medicine Department, Faculty of Medicine, University of Indonesia, JL. Pegangsaan Timur 16, Jakarta Pusat 10320, Indonesia; Department of Allergology, University Hospital Groningen, 9700 RB Groningen, Netherlands
Suarthana, E., Environmental Epidemiology Division, Institute for Risk Assessment Sciences (IRAS), Utrecht University, 3508 TD, Utrecht, Netherlands, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, 3508 GA, Utrecht, Netherlands, Community Medicine Department, Faculty of Medicine, University of Indonesia, JL. Pegangsaan Timur 16, Jakarta Pusat 10320, Indonesia; Vergouwe, Y., Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, 3508 GA, Utrecht, Netherlands; Moons, K.G., Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, 3508 GA, Utrecht, Netherlands; De Monchy, J., Department of Allergology, University Hospital Groningen, 9700 RB Groningen, Netherlands; Grobbee, D., Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, 3508 GA, Utrecht, Netherlands; Heederik, D., Environmental Epidemiology Division, Institute for Risk Assessment Sciences (IRAS), Utrecht University, 3508 TD, Utrecht, Netherlands; Meijer, E., Environmental Epidemiology Division, Institute for Risk Assessment Sciences (IRAS), Utrecht University, 3508 TD, Utrecht, Netherlands
Objectives: To develop and validate a prediction model to detect sensitization to wheat allergens in bakery workers. Study Design and Setting: The prediction model was developed in 867 Dutch bakery workers (development set, prevalence of sensitization 13%) and included questionnaire items (candidate predictors). First, principal component analysis was used to reduce the number of candidate predictors. Then, multivariable logistic regression analysis was used to develop the model. Internal validation and extent of optimism was assessed with bootstrapping. External validation was studied in 390 independent Dutch bakery workers (validation set, prevalence of sensitization 20%). Results: The prediction model contained the predictors nasoconjunctival symptoms, asthma symptoms, shortness of breath and wheeze, work-related upper and lower respiratory symptoms, and traditional bakery. The model showed good discrimination with an area under the receiver operating characteristic (ROC) curve area of 0.76 (and 0.75 after internal validation). Application of the model in the validation set gave a reasonable discrimination (ROC area = 0.69) and good calibration after a small adjustment of the model intercept. Conclusion: A simple model with questionnaire items only can be used to stratify bakers according to their risk of sensitization to wheat allergens. Its use may increase the cost-effectiveness of (subsequent) medical surveillance. © 2010 Elsevier Inc. All rights reserved.
Baker; Diagnostic model; Occupational allergic disease; Sensitization; Validity; Wheat; Wheat allergens
adolescent; adult; aged; allergic asthma; article; dyspnea; female; human; lower respiratory tract infection; major clinical study; male; prevalence; priority journal; sensitization; upper respiratory tract infection; wheat allergy; wheezing; asthma; cluster analysis; flour; hypersensitivity; immunology; middle aged; Netherlands; Occupational Diseases; occupational exposure; principal component analysis; questionnaire; receiver operating characteristic; risk assessment; validation study; wheat; young adult; Adolescent; Adult; Aged; Allergens; Asthma; Cluster Analysis; Female; Flour; Humans; Hypersensitivity; Male; Middle Aged; Netherlands; Occupational Diseases; Occupational Exposure; Prevalence; Principal Component Analysis; Questionnaires; Risk Assessment; ROC Curve; Triticum; Young Adul
08954356
JCEPE
20189762
Article
Q1