Publikasi Scopus FKUI Tahun 2010 s/d 2020 (data Per 3 Februari 2021)

Surjawan Y., Setiabudy R.D., Suryaatmadja M., Ranakusuma T.A.S.
57192889315;57205092888;6506468294;7801656487;
The association of plasminogen activator inhibitor-1 level with ischemic stroke (preliminary study)
2010
Medical Journal of Indonesia
19
3
158
163
2
Department of Clinical Pathology, Faculty of Medicine, University of Indonesia, Dr. Ciptomangunkusumo Central National Hospital, Jakarta, Indonesia; Department of Neurology, Faculty of Medicine, University of Indonesia, Dr. Ciptomangunkusumo Central National Hospital, Jakarta, Indonesia
Surjawan, Y., Department of Clinical Pathology, Faculty of Medicine, University of Indonesia, Dr. Ciptomangunkusumo Central National Hospital, Jakarta, Indonesia; Setiabudy, R.D., Department of Clinical Pathology, Faculty of Medicine, University of Indonesia, Dr. Ciptomangunkusumo Central National Hospital, Jakarta, Indonesia; Suryaatmadja, M., Department of Clinical Pathology, Faculty of Medicine, University of Indonesia, Dr. Ciptomangunkusumo Central National Hospital, Jakarta, Indonesia; Ranakusuma, T.A.S., Department of Neurology, Faculty of Medicine, University of Indonesia, Dr. Ciptomangunkusumo Central National Hospital, Jakarta, Indonesia
Aim Recently, increased plasminogen activator inhibitor-1 (PAI-1) has been known a risk factor for ischemic heart disease. However, the association of increased PAI-1 level with ischemic stroke remains unclear. The aim of this study was to analyze the association of PAI-1 level with ischemic stroke. Methods By case control design we involved 38 ischemic stroke and 38 risky-matched control subjects who fulfilled the criteria. The PAI-1 level was determined by ELISA method using Asserachrom PAI-1 from Stago. Results High PAI-1 level was found more frequent in ischemic stroke subjects than in control subjects (21.1% vs. 7.9 % with OR 3.1; 95 % CI 0.757 – 12.790). The analysis of all studied subjects showed that there was a weak negative correlation between PAI-1 level and age (r = -0.4; P = 0.000). High PAI-1 level was found more frequent in younger (40 – 58 years old) than in the older subjects (60 – 84 years old) (20% vs. 9.8 %) (p=0.004). Conclusion The result of this preliminary study suggested an association between PAI-1 level and ischemic stroke in younger age. Further study with larger subjects is recommended to confirm this association. © 2010, Faculty of Medicine, Universitas Indonesia. All rights reserved.
Ischemic stroke; Plasminogen activator inhibitor-1; Stroke risk factors
plasminogen activator inhibitor 1; adult; age; aged; Article; brain ischemia; case control study; clinical article; controlled study; correlation analysis; disease association; enzyme linked immunosorbent assay; female; human; male; middle aged; risk factor; very elderly
Faculty of Medicine, Universitas Indonesia
08531773
Article
Q4