Publikasi Scopus FKUI Tahun 2010 s/d 2020 (data Per 3 Februari 2021)

Syam A.F., Abdullah M., Rani A.A., Nurdjanah S., Adi P., Djumhana A., Tarigan P., Wibawa I.D.N.
8443384400;7103393434;7006676360;57209198952;6507672162;6506054984;15053882800;57192185799;
A comparison of 5 or 7 days of rabeprazole triple therapy for eradication of Helicobacter pylori
2010
Medical Journal of Indonesia
19
2
113
117
1
Division of Gastroenterology, Department of Internal Medicine, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Division of Gastroentero-Hepatology, Department of Internal Medicine, Dr. Sardjito Hospital, Faculty of Medicine Gajah Mada University, Yogyakarta, Indonesia; Division of Gastroenterology, Department of Internal Medicine, Dr. Sutomo Hospital, Faculty of Medicine, Airlangga University, Surabaya, Indonesia; Division of Gastroentero-Hepatology, Department of Internal Medicine, Dr. Hasan Sadikin Hospital, Faculty of Medicine, Padjajaran University, Bandung, Indonesia; Division of Gastroentero-Hepatology, Department of Internal Medicine, H. Adam Malik Hospital, Faculty of Medicine, Sumatera Utara University, Medan, Indonesia; Department of Internal Medicine, Sanglah Hospital, Faculty of Medicine, Udayana University, Denpasar, Indonesia
Syam, A.F., Division of Gastroenterology, Department of Internal Medicine, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Abdullah, M., Division of Gastroenterology, Department of Internal Medicine, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Rani, A.A., Division of Gastroenterology, Department of Internal Medicine, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Nurdjanah, S., Division of Gastroentero-Hepatology, Department of Internal Medicine, Dr. Sardjito Hospital, Faculty of Medicine Gajah Mada University, Yogyakarta, Indonesia; Adi, P., Division of Gastroenterology, Department of Internal Medicine, Dr. Sutomo Hospital, Faculty of Medicine, Airlangga University, Surabaya, Indonesia; Djumhana, A., Division of Gastroentero-Hepatology, Department of Internal Medicine, Dr. Hasan Sadikin Hospital, Faculty of Medicine, Padjajaran University, Bandung, Indonesia; Tarigan, P., Division of Gastroentero-Hepatology, Department of Internal Medicine, H. Adam Malik Hospital, Faculty of Medicine, Sumatera Utara University, Medan, Indonesia; Wibawa, I.D.N., Department of Internal Medicine, Sanglah Hospital, Faculty of Medicine, Udayana University, Denpasar, Indonesia
Aim A combination of PPI and 1000 mg amoxicillin/500 mg clarithromycin twice daily for 2 weeks has been proven effective in the eradication of H. pylori. Most studies suggested that treatment for 7 and 10 days may be equally effective. Few data are available on the efficacy of 5-day triple therapy. Aim of this study was to compare 5-day and 7-day rabeprazole triple therapy for eradication of H. pylori infection. Methods We prospectively studied 60 consecutive H. pylori-infected patients who came to hospitals in six centres in Indonesia and who underwent upper endoscopy and biopsy. H. pylori infection was confirmed if two rapid urease tests (Pronto Dry) and histology or urea breath test were positive. Patients were assigned to either an open-labelled 5-day or 7-day course of oral amoxicillin 1000 mg b.i.d., clarithromycin 500 mg b.i.d., and rabeprazole 10 mg b.i.d. (RAC). Four weeks after therapy, all patients had a repeated UBT for evaluation of the presence of H. pylori. Results Of the 60 patients (42 male and 18 females) with mean age (± SD) 47.63 ± 13.93 years, range 21–74 years, 25 patients (41.7%) had 5-day treatment and 35 patients (58.3%) had 7-day treatment. With 5-day treatment, 18 patients (72%) and with 7-day treatment 32 patients (91.4%) became negative for H. pylori infection. The eradication failure was found on 7 patients (28.0%) in 5-day treatment and 3 patients (8.6%) in 7-day treatment. Conclusions The study showed that the eradication of H. pylori infection by triple rabeprazole-based treatment in 7-day is still better than in 5-day. © 2010, Faculty of Medicine, Universitas Indonesia. All rights reserved.
H. pylori; Rabeprazole; Triple therapy
amoxicillin; clarithromycin; rabeprazole; adult; aged; Article; bacterial clearance; controlled study; dosage schedule comparison; drug treatment failure; female; Helicobacter infection; histopathology; human; human tissue; major clinical study; male; multicenter study; prospective study; randomized controlled trial; rapid urease test; urea breath test
Faculty of Medicine, Universitas Indonesia
08531773
Article
Q4