Publikasi Scopus FKUI Tahun 2010 s/d 2020 (data Per 3 Februari 2021)

Idris N.S., Dwipoerwantoro P.G., Kurniawan A., Said M.
55750761100;36150125900;6506883360;7103287094;
Intestinal parasitic infection of immunocompromised children with diarrhoea: Clinical profile and therapeutic response
2010
Journal of Infection in Developing Countries
4
5
309
317
34
Departments of Child Health, Faculty of Medicine, University of Indonesia/Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Departments of Parasitology, Faculty of Medicine, University of Indonesia/Cipto Mangunkusumo General Hospital, Jakarta, Indonesia
Idris, N.S., Departments of Child Health, Faculty of Medicine, University of Indonesia/Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Dwipoerwantoro, P.G., Departments of Child Health, Faculty of Medicine, University of Indonesia/Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Kurniawan, A., Departments of Parasitology, Faculty of Medicine, University of Indonesia/Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Said, M., Departments of Parasitology, Faculty of Medicine, University of Indonesia/Cipto Mangunkusumo General Hospital, Jakarta, Indonesia
Background: Parasitic gastrointestinal infections have been variably reported among immunocompromised adults while data on children have been limited. This prospective cross-sectional study aimed to assess the clinical profile of intestinal parasitic infections among immunocompromised children with diarrhoea and their treatment response. Methodology: Two freshly voided stool samples taken for two consecutive days were examined by direct and formalin-ether concentrated smears. Modified Ziehl-Neelsen staining was used to detect Cryptosporidium, Isospora belli, and Cyclospora cayetanensis. Blastocystis hominis was identified using in vitro culture. Subjects positive for stool parasite(s) received standard therapy according to the aetiology and were evaluated afterward. Results: Forty-two subjects from Jakarta, Indonesia were included in this study, mostly aged one to five years (78%) and HIV infected (52%). Parasites were found in 24/42 (57%) subjects in which B. hominis comprised the largest proportion (23/24 = 96%). Cryptosporidium was identified in two subjects who were HIV infected with CD4 percentages of < 15%. No helminth infestations were found. Parasites were most frequently found in preschool age children (16/23), in those with recurrent or watery diarrhoea (23/24 and 14/18, respectively), and in HIV subjects not receiving antiretrovirals (16/22). Of 13 subjects evaluated for response to a 10-day metronidazole course for B. hominis infection, seven achieved clinical remission and nine had their parasites eradicated. Conclusions: The prevalence of intestinal parasitic infection in immunocompromised children with persistent and/or recurrent diarrhoea is moderately high and dominated by B. hominis infection. Clinical remission and parasite eradication can be achieved in B. hominis infection treated with metronidazole. © 2010 Idris et al.
B. hominis; Diarrhoea; Hiv; Immunocompromised; Metronidazole
cotrimoxazole; lamivudine; metronidazole; nevirapine; paromomycin; zidovudine; adolescent; article; bacterium detection; Blastocystis hominis; child; Cryptosporidium; Cyclospora cayetanensis; diarrhea; feces analysis; female; human; Human immunodeficiency virus infection; immunocompromised patient; infant; Isospora belli; major clinical study; male; parasitosis; prevalence; cross-sectional study; Human immunodeficiency virus infection; immunocompromised patient; intestine infection; isolation and purification; parasitology; preschool child; prospective study; Blastocystis hominis; Cryptosporidium; Cyclospora cayetanensis; Isospora belli; Vermes; Blastocystis hominis; Child; Child, Preschool; Cross-Sectional Studies; Cryptosporidium; Diarrhea; Female; HIV Infections; Humans; Immunocompromis
Journal of Infection in Developing Countries
20366590
20539063
Article
Q3