Publikasi Scopus FKUI Tahun 2010 s/d 2020 (data Per 3 Februari 2021)

Bawazier L.A., Sja'bani M., Haryana S.M., Soesatyo M.H., Sadewa A.H.
23471654800;6504624211;6507708439;6602370539;6506553494;
Relationship of angiotensin converting enzyme gene polymorphism and hypertension in Yogyakarta, Indonesia.
2010
Acta medica Indonesiana
42
4
192
198
14
Department of Internal Medicine, Faculty of Medicine, University of Indonesia-dr. Cipto Mangunkusumo Hospital. Jl. Diponegoro no. 71, Jakarta Pusat, 10430, Indonesia
Bawazier, L.A., Department of Internal Medicine, Faculty of Medicine, University of Indonesia-dr. Cipto Mangunkusumo Hospital. Jl. Diponegoro no. 71, Jakarta Pusat, 10430, Indonesia; Sja'bani, M.; Haryana, S.M.; Soesatyo, M.H.; Sadewa, A.H.
To evaluate the association between ACE gene polymorphism I/D and hypertension in Yogyakarta population. This study is a cross-sectional. Sample was taken by random sampling method from hypertensive, prehypertensve and normotensive subjects; from that were obtained 125 subjects, 97 subjects and 108 subjects, consecutively. ACE gene polymorphism I/D was examined by PCR. Genotype was classified as II, ID, or DD based on positive or negative insertion/delation allele. This study shows significant differences of three groups (ages, body mass index (BMI), and family history of hypertension) and total cholesterol level in blood, which tends to have greater value in the hypertension group. Frequency of genotype II, ID, DD are 85 (68%), 39 (31.2%), 1 (0.8%) in hypertension, 66 (61.1%), 38 (35.2%), 4 (3.7%) in normo-tension and 56 (57.7%), 37 (38.1%), 4 (4.1%) in pre-hypertension subject, consecutively. Chi-square analysis shows statistically significant association between ID+DD vs. II genotype and hypertension. Multiple logistic regression analysis shows four variables that significantly influence to hypertension, namely ages, family history of hypertension, BMI, and ACE gene polymorphism. ACE ID+DD genotype has significant relationship with hypertension in Melati population, Sleman, Yogyakarta, Indonesia.
dipeptidyl carboxypeptidase; adult; article; body mass; chi square distribution; confidence interval; cross-sectional study; enzymology; female; gene deletion; genetic polymorphism; genetics; genotype; human; hypertension; Indonesia; male; middle aged; multivariate analysis; nonparametric test; questionnaire; risk; statistical model; Adult; Body Mass Index; Chi-Square Distribution; Confidence Intervals; Cross-Sectional Studies; Female; Gene Deletion; Genotype; Humans; Hypertension; Indonesia; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Questionnaires; Statistics, Nonparametric
01259326
21063039
Article
Q3