No records
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111 |
Baskoro J.C., Hadi I.A.N., Ekaputri M., Winarsih N.S. |
57242005500;57242308100;57242005600;57211183552; |
Correlation between duration of untreated psychosis and working memory in early-onset psychotic disorders |
2021 |
Personalized Medicine in Psychiatry |
29-30 |
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100084 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114078676&doi=10.1016%2fj.pmip.2021.100084&partnerID=40&md5=56d11228ab6c85aba3075e3f4f99e800 |
Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya 6, Jakarta Pusat, DKI, Jakarta, 10430, Indonesia |
Baskoro, J.C., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya 6, Jakarta Pusat, DKI, Jakarta, 10430, Indonesia; Hadi, I.A.N., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya 6, Jakarta Pusat, DKI, Jakarta, 10430, Indonesia; Ekaputri, M., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya 6, Jakarta Pusat, DKI, Jakarta, 10430, Indonesia; Winarsih, N.S., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya 6, Jakarta Pusat, DKI, Jakarta, 10430, Indonesia |
Psychotic disorders are morbid mental disorders that impair working memory. Theory suggests that longer duration of untreated psychosis (DUP) results in worse working memory. However, results from previous studies are contradictory, with no study having been conducted in children. This study aims at finding out the association between duration of untreated psychosis and working memory in children. This is a cross-sectional study with 45 subjects. DUP was collected from medical records whereas working memory was measured using digit span backward raw score. Average digit span backward scores of subjects was 3.7 ± 1.18. Analysis using Spearman test showed no significant association (p = 0.128) between DUP and working memory. In conclusion, there is no association between DUP and working memory in children, therefore we recommend that psychiatrists pay attention to working memory impairment in all pediatric patients with psychotic disorders, regardless of their DUP. © 2021 Elsevier Inc. |
Children; Duration of untreated psychosis; Psychosis; Working memory |
neuroleptic agent; acute psychosis; adolescent; adult; Article; attention; child; child psychiatry; clinical article; clinical assessment; clinical feature; controlled study; correlation analysis; cross-sectional study; digit span backward raw score; disease association; disease duration; duration of untreated psychosis; female; human; male; medical record; medication compliance; memory test; outcome assessment; patient compliance; pediatric patient; psychosis; schizophrenia; treatment duration; working memory |
Elsevier Inc. |
24681717 |
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Article |
#N/A |
#N/A |
#N/A |
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112 |
Ong J., Ong A.M.L., Ong S., Xin X., Lee Y.Y., Pausawasdi N., De Lusong M.A., Makmun D., Chong V.H., Ho S.H., Lim W., Ong D., Dan Y.Y., Khor C. |
57193716100;36942342000;35741447900;57326122500;56191149300;6602327609;23767987600;16638046900;54790563600;50561284200;57194415809;56013316700;8699022400;8549610200; |
The impact of the coronavirus disease 2019 pandemic on gastroenterologists in Southeast Asia: A mixed-methods study |
2021 |
Journal of Gastroenterology and Hepatology (Australia) |
36 |
11 |
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3056 |
3068 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112680822&doi=10.1111%2fjgh.15594&partnerID=40&md5=3c1bb0505aa3a502aa7cea4abadd518a |
Department of Medicine, National University of Singapore, Singapore; Department of Engineering, University of Cambridge, Cambridge, United Kingdom; Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore; Duke-NUS Medical School, Singapore; Department of Surgical Intensive Care, Singapore General Hospital, Singapore; Department of Anaesthesiology, Sengkang General Hospital, Singapore; Health Services Research Unit, Singapore General Hospital, Singapore; School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Malaysia; GI Function and Motility Unit, Hospital Universiti Sains Malaysia, Kota Bharu, Malaysia; Division of Gastroenterology, Department of Medicine, Mahidol University Faculty of Medicine at Siriraj Hospital, Bangkok, Thailand; Section of Advanced Endoscopy, Division of Gastroenterology, Department of Medicine, Philippine General Hospital, Manila, Philippines; Faculty of Medicine, Division of Gastroenterology, Department of Internal Medicine, Cipto Mangunkusumo National General Hospital, Universitas Indonesia, Jakarta, Indonesia; Gastroenterology Unit, Department of Medicine, RIPAS Hospital, Bandar Seri Begawan, Brunei Darussalam; Institute of Health Sciences, PAPRSB Universiti of Brunei Darussalam, Bandar Seri Begawan, Brunei Darussalam; Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia; Department of Anaesthesiology, Singapore General Hospital, Singapore; Department of Medicine, Division of Gastroenterology and Hepatology, National University Hospital, Singapore |
Ong, J., Department of Medicine, National University of Singapore, Singapore, Department of Engineering, University of Cambridge, Cambridge, United Kingdom; Ong, A.M.L., Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore, Duke-NUS Medical School, Singapore; Ong, S., Department of Surgical Intensive Care, Singapore General Hospital, Singapore, Department of Anaesthesiology, Sengkang General Hospital, Singapore; Xin, X., Health Services Research Unit, Singapore General Hospital, Singapore; Lee, Y.Y., School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Malaysia, GI Function and Motility Unit, Hospital Universiti Sains Malaysia, Kota Bharu, Malaysia; Pausawasdi, N., Division of Gastroenterology, Department of Medicine, Mahidol University Faculty of Medicine at Siriraj Hospital, Bangkok, Thailand; De Lusong, M.A., Section of Advanced Endoscopy, Division of Gastroenterology, Department of Medicine, Philippine General Hospital, Manila, Philippines; Makmun, D., Faculty of Medicine, Division of Gastroenterology, Department of Internal Medicine, Cipto Mangunkusumo National General Hospital, Universitas Indonesia, Jakarta, Indonesia; Chong, V.H., Gastroenterology Unit, Department of Medicine, RIPAS Hospital, Bandar Seri Begawan, Brunei Darussalam, Institute of Health Sciences, PAPRSB Universiti of Brunei Darussalam, Bandar Seri Begawan, Brunei Darussalam; Ho, S.H., Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia; Lim, W., Department of Anaesthesiology, Sengkang General Hospital, Singapore, Department of Anaesthesiology, Singapore General Hospital, Singapore; Ong, D., Department of Medicine, Division of Gastroenterology and Hepatology, National University Hospital, Singapore; Dan, Y.Y., Department of Medicine, National University of Singapore, Singapore, Department of Medicine, Division of Gastroenterology and Hepatology, National University Hospital, Singapore; Khor, C., Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore, Duke-NUS Medical School, Singapore |
Background and Aim: The coronavirus disease 2019 pandemic has impacted gastroenterology practices worldwide; however, its protracted effects within Southeast Asia were unknown. The primary aim of the study was to determine the impact of the pandemic on clinical demands including burnout among gastroenterologists within the region. The secondary aim was to identify risk factors for burnout and determine regional stressors. Methods: This was a mixed-methods study. Gastroenterologists were surveyed electronically between September 1 and December 7, 2020, via gastroenterology and endoscopy societies of Brunei, Indonesia, Malaysia, Philippines, Singapore, and Thailand. Quantitative and qualitative data were collected. The 22-item Maslach Burnout Inventory-Human Services Survey (MBI-HSS) was used to detect burnout. Quantitative data were non-parametric; non-parametric methods were used for statistical comparisons. Logistic regression was used to determine risk factors for burnout. Content analysis method was used to analyze qualitative data. Ethical approval was obtained. Results: A total of 73.0% reported that they were still significantly affected by the pandemic. Of these, 40.5% reported increased workload and 59.5% decreased workload. Statistically significant differences in weekly working hours, endoscopy, and inpatient volumes were present. No differences were observed in outpatient volumes, likely because of telemedicine. Burnout was common; however, 50.1% of gastroenterologists were unaware of or did not have access to mental health support. This, as well as depression, being a trainee, and public sector work, increased burnout risk significantly. Conclusion: The effects of the pandemic are multifaceted, and burnout is common among Southeast Asian gastroenterologists. Safeguards for mental health are suboptimal, and improvements are urgently needed. © 2021 The Authors. Journal of Gastroenterology and Hepatology published by Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd. |
burnout; COVID-19; gastroenterologists; gastroenterology; pandemic |
adult; Article; Brunei Darussalam; content analysis; controlled study; coronavirus disease 2019; data collection method; depression; endoscopy; female; gastroenterologist; hospital patient; human; Indonesia; job stress; logistic regression analysis; major clinical study; Malaysia; male; Maslach Burnout Inventory-Human Services Survey; mental health; multicenter study; nonparametric test; pandemic; Philippines; professional burnout; public sector; qualitative research; quantitative analysis; risk factor; Singapore; Southeast Asia; telemedicine; Thailand; workload; burnout; epidemiology; gastroenterologist; middle aged; pandemic; psychology; questionnaire; Adult; Asia, Southeastern; Burnout, Professional; COVID-19; Female; Gastroenterologists; Humans; Male; Middle Aged; Pandemics; SARS-CoV-2 |
John Wiley and Sons Inc |
08159319 |
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34159640 |
Article |
Q1 |
1214 |
3242 |
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113 |
Tirtayasa P.M.W., Samuel A.G., Lisnawati, Retnowulan A. |
56245176500;57226642220;24449072000;57226640316; |
Parameatal glans cyst: A case report |
2021 |
Urology Case Reports |
39 |
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101802 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112167978&doi=10.1016%2fj.eucr.2021.101802&partnerID=40&md5=a508fda307bc2bbe4ba2dcbc8048eb84 |
Department of Urology, Faculty of Medicine Universitas Udayana, Bali, Indonesia; Urology Consultant, Pelni General Hospital, Jakarta, Indonesia; Pathology Consultant, Pelni General Hospital, Jakarta, Indonesia; Department of Pathological Anatomy, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Tirtayasa, P.M.W., Department of Urology, Faculty of Medicine Universitas Udayana, Bali, Indonesia; Samuel, A.G., Urology Consultant, Pelni General Hospital, Jakarta, Indonesia; Lisnawati, Pathology Consultant, Pelni General Hospital, Jakarta, Indonesia, Department of Pathological Anatomy, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Retnowulan, A., Pathology Consultant, Pelni General Hospital, Jakarta, Indonesia, Department of Pathological Anatomy, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Parameatal glans cyst is unusual and only a few cases reported until currently. We presented a four-year-old boy with dysuria and inappropriate appearance of parameatal glans cyst. The cystic mass was slow-growing and was present since birth. Complete surgical excision was performed to prevent recurrencies and to achieve good cosmesis. © 2021 The Authors |
Glans cyst; Parameatal cyst; Urethral cyst |
Article; case report; child; clinical article; cuboidal epithelium; cyst; dysuria; epithelium; esthetic surgery; excision; follow up; general anesthesia; globular cystic swelling; histopathology; human; human tissue; male; parameatal glans cyst; penis glans; physical examination; preschool child; squamous epithelium; swelling; urethra; urethral meatus; urinalysis |
Elsevier Inc. |
22144420 |
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Article |
Q3 |
245 |
16962 |
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114 |
Andrianto, Al-Farabi M.J., Nugraha R.A., Marsudi B.A., Azmi Y. |
57221812919;57210466548;57200701510;57201975146;57200278939; |
Biomarkers of endothelial dysfunction and outcomes in coronavirus disease 2019 (COVID-19) patients: A systematic review and meta-analysis |
2021 |
Microvascular Research |
138 |
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104224 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111341102&doi=10.1016%2fj.mvr.2021.104224&partnerID=40&md5=d5cc3fe2a0d5a70658ecff8ad7fa6f8b |
Department of Cardiology and Vascular Medicine, Soetomo General Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, 60286, Indonesia; Department of Cardiology and Vascular Medicine, National Cardiovascular Center Harapan Kita, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Faculty of Medicine, Universitas Airlangga, Surabaya, 60286, Indonesia |
Andrianto, Department of Cardiology and Vascular Medicine, Soetomo General Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, 60286, Indonesia; Al-Farabi, M.J., Department of Cardiology and Vascular Medicine, Soetomo General Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, 60286, Indonesia; Nugraha, R.A., Department of Cardiology and Vascular Medicine, Soetomo General Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, 60286, Indonesia; Marsudi, B.A., Department of Cardiology and Vascular Medicine, National Cardiovascular Center Harapan Kita, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Azmi, Y., Faculty of Medicine, Universitas Airlangga, Surabaya, 60286, Indonesia |
Background: Several studies have reported that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can directly infect endothelial cells, and endothelial dysfunction is often found in severe cases of coronavirus disease 2019 (COVID-19). To better understand the prognostic values of endothelial dysfunction in COVID-19-associated coagulopathy, we conducted a systematic review and meta-analysis to assess biomarkers of endothelial cells in patients with COVID-19. Methods: A literature search was conducted on online databases for observational studies evaluating biomarkers of endothelial dysfunction and composite poor outcomes in COVID-19 patients. Results: A total of 1187 patients from 17 studies were included in this analysis. The estimated pooled means for von Willebrand Factor (VWF) antigen levels in COVID-19 patients was higher compared to healthy control (306.42 [95% confidence interval (CI) 291.37–321.48], p < 0.001; I2:86%), with the highest VWF antigen levels was found in deceased COVID-19 patients (448.57 [95% CI 407.20–489.93], p < 0.001; I2:0%). Meta-analysis showed that higher plasma levels of VWF antigen, tissue-type plasminogen activator (t-PA), plasminogen activator inhibitor-1 antigen (PAI-1) antigen, and soluble thrombomodulin (sTM) were associated with composite poor outcome in COVID-19 patients ([standardized mean difference (SMD) 0.74 [0.33–1.16], p < 0.001; I2:80.4%], [SMD 0.55 [0.19–0.92], p = 0.003; I2:6.4%], [SMD 0.33 [0.04–0.62], p = 0.025; I2:7.9%], and [SMD 0.55 [0.10–0.99], p = 0.015; I2:23.6%], respectively). Conclusion: The estimated pooled means show increased levels of VWF antigen in COVID-19 patients. Several biomarkers of endothelial dysfunction, including VFW antigen, t-PA, PAI-1, and sTM, are significantly associated with increased composite poor outcomes in patients with COVID-19. PROSPERO registration number: CRD42021228821 © 2021 Elsevier Inc. |
COVID-19; Endothelial dysfunction; Plasminogen activator inhibitor-1; Thrombomodulin; Tissue-type plasminogen activator; von Willebrand Factor |
biological marker; plasminogen activator inhibitor 1; thrombomodulin; tissue plasminogen activator; von Willebrand factor; biological marker; plasminogen activator inhibitor 1; SERPINE1 protein, human; THBD protein, human; thrombomodulin; tissue plasminogen activator; von Willebrand factor; adult; aged; Article; clinical outcome; controlled study; coronavirus disease 2019; endothelial dysfunction; female; human; major clinical study; male; publication bias; systematic review; blood; diagnosis; meta analysis; metabolism; middle aged; pathophysiology; predictive value; prognosis; therapy; vascular endothelium; very elderly; Adult; Aged; Aged, 80 and over; Biomarkers; COVID-19; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Predictive Value of Tes |
Academic Press Inc. |
00262862 |
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34273359 |
Article |
Q2 |
819 |
5848 |
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115 |
Meutia A.P., Yonathan K., Widia F. |
57203368133;57226144513;26028200800; |
Giant urethral caruncle resembling urethral prolapse causing outflow obstruction |
2021 |
Urology Case Reports |
39 |
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101783 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110776549&doi=10.1016%2fj.eucr.2021.101783&partnerID=40&md5=01ebfd6f9c1caac70e9244d1c3ffe391 |
Division of Urogynecology and Reconstruction Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Urogynecology Clinic, Bunda General Hospital, Jakarta, Indonesia; Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Department of Urology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia |
Meutia, A.P., Division of Urogynecology and Reconstruction Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia, Urogynecology Clinic, Bunda General Hospital, Jakarta, Indonesia; Yonathan, K., Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Widia, F., Department of Urology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia |
Urethral caruncle is a rare condition primarily affecting elderly. Sometimes, it resembles urethral prolapse or malignancies. It can even cause outflow obstruction or urinary retention. A case of 83-years-old woman with urinary retention since a week prior was presented. Physical examination revealed a bulging mass originating from posterior lip of external urethral meatus. Due to the size, it caused outflow obstruction. The whole mass was excised. Histology examination reported the mass as urethral caruncle. Urethral caruncle is a common problem in elderly which rarely cause outflow obstruction. A thorough examination is required to distinguish it from malignancies and other disorders. © 2021 |
Pelvic organ prolapse; Urethral caruncle; Urethral disease |
aged; Article; blood cell count; case report; clinical article; female; general anesthesia; histology; histopathology; human; human tissue; pelvic examination; physical examination; postmenopause; urethra disease; urethra obstruction; urethral caruncle; urethral prolapse; urine retention; uroflowmetry; urothelium; vital sign |
Elsevier Inc. |
22144420 |
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Article |
Q3 |
245 |
16962 |
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116 |
Munadzilah S., Hegar B., Sekartini R., Vandenplas Y. |
57346126700;6506273944;57224503576;57223670656; |
Association between milk consumption and lactose malabsorption in Indonesian children |
2021 |
Chinese Journal of Contemporary Pediatrics |
23 |
10 |
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975 |
980 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119440135&doi=10.7499%2fj.issn.1008-8830.2105030&partnerID=40&md5=80626db7ac7feaae0925a1057b4f77eb |
Department of Child Health, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Kidz Health Castle, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium |
Munadzilah, S., Department of Child Health, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Hegar, B., Department of Child Health, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Sekartini, R., Department of Child Health, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Vandenplas, Y., Kidz Health Castle, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium |
Objective To study the association between milk consumption and lactose malabsorption in Indonesian children aged 3-12 years. Methods This cross sectional study was conducted in randomly selected presumed healthy children with good nutritional status aged 3-12 years in Central Jakarta, Indonesia (n=174), including 72 children aged 3-5 years and 102 children aged 6-12 years. Results The prevalence of lactose malabsorption in children aged 3-5 years and children aged 6-12 years was 20.8% (15/72) and 35.3% (36/102), respectively. There was no association between milk or milk product consumption and lactose malabsorption (P>0.05). In the 51 children with lactose malabsorption, the predominant clinical symptoms were diarrhea (62%), abdominal pain (52%), and nausea (5%) during the hydrogen breath test. Conclusions There is no association between milk consumption and lactose malabsorption in Indonesian children aged 3-12 years, suggesting that genetic predisposition may be more important than adaptive mechanisms to lactose consumption. © 2021 Xiangya Hospital of CSU. All rights reserved. |
Child; Hydrogen breath test; Lactose malabsorption; Milk consumption; Prevalence |
abdominal pain; adult; Article; child; cross-sectional study; dairy product; diarrhea; disease association; female; genetic predisposition; human; hydrogen breath test; lactose intolerance; male; milk; nausea; prevalence; animal; breath analysis; Indonesia; lactose intolerance; milk; Animals; Breath Tests; Child; Cross-Sectional Studies; Humans; Indonesia; Lactose Intolerance; Milk |
Central South University |
10088830 |
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34719410 |
Article |
Q3 |
174 |
21112 |
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117 |
Umiatin, Indrasari W., Taryudi, Sari P., Mazfufah N.F., Rosadi I. |
57202292099;56069603500;57003576500;55776482300;57215595521;57204720098; |
Effect of pulse electromagnetic field exposure on the expression of lipo protein lipase (LPL) on the differentiation of mesenchymal stem cell |
2021 |
Journal of Physics: Conference Series |
2019 |
1 |
012107 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119203085&doi=10.1088%2f1742-6596%2f2019%2f1%2f012107&partnerID=40&md5=cd764de9d9b9c1287f97fb09cfd8eea2 |
Department of Physics, Faculty of Mathematics and Natural Science, Universitas Negeri Jakarta, Indonesia; Department of Electronic Engineering, Faculty of Engineering, Universitas Negeri Jakarta, Indonesia; Department of Biology, Faculty of Medicine, Universitas Indonesia, Indonesia, Jl. Rawamangun Muka, Jakarta, 13220, Indonesia; Stem Cells and Tissue Engineering Research Center, IMERI, Faculty of Medicine, Universitas Indonesia, Indonesia; Department of Biology, Faculty of Mathematics and Natural Sciences, Mulawarman University, Samarinda, Indonesia |
Umiatin, Department of Physics, Faculty of Mathematics and Natural Science, Universitas Negeri Jakarta, Indonesia; Indrasari, W., Department of Physics, Faculty of Mathematics and Natural Science, Universitas Negeri Jakarta, Indonesia; Taryudi, Department of Electronic Engineering, Faculty of Engineering, Universitas Negeri Jakarta, Indonesia; Sari, P., Department of Biology, Faculty of Medicine, Universitas Indonesia, Indonesia, Jl. Rawamangun Muka, Jakarta, 13220, Indonesia; Mazfufah, N.F., Stem Cells and Tissue Engineering Research Center, IMERI, Faculty of Medicine, Universitas Indonesia, Indonesia; Rosadi, I., Department of Biology, Faculty of Mathematics and Natural Sciences, Mulawarman University, Samarinda, Indonesia |
Pulsed electromagnetic fields (PEMFs) have an important role in cell differentiation. Previous study reported that PEMFs had positive and negative effect towards cell differentiation that depends on their frequencies applied to the cells. Human adipose-derived stem cells (ASCs) are mesenchymal stem cells that have an ability to differentiate into several types of cell including adipocytes, chondrocytes and osteocytes. This study aimed to evaluate the effect of human ASCs towards their adipogenic differentiation during PEMFs exposure. Human ASCs were isolated from adipose tissue. The cells then cultured in specific medium of adipocyte that induced ASCs differentiation along with PEMFs exposure. The maximum magnetic field used is 2 mT with a frequency of 75 Hz. To confirm the effect of PEMFs exposure towards adipogenic differentiation, mRNA expression of lipo protein lipase (LPL) was measured in mRNA expression level. The results showed that ASCs cultured on adipogenic differentiation without PEMFs exposure gradually increased LPL expression until day 14 of observation, while ASCs with PEMFs exposure significantly decreased LPL expression from day 2 to day 14. Based on the results, we concluded that PEMFs exposure can inhibit LPL expression that suppressed adipogenic differentiation. © 2021 Institute of Physics Publishing. All rights reserved. |
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Electromagnetic field effects; Electromagnetic fields; Proteins; Stem cells; Adipogenic differentiations; Adipose derived stem cells; Cell differentiation; Cell-be; Cell/B.E; Electromagnetic field exposure; Human adipose; Lipo proteins; Mesenchymal stem cell; Pulsed electromagnetic fields; Cell culture |
IOP Publishing Ltd |
17426588 |
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Conference Paper |
Q4 |
210 |
18731 |
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118 |
Sen L.T., Siste K., Hanafi E., Murtani B.J., Christian H., Limawan A.P., Adrian, Siswidiani L.P. |
57219034101;55644113100;56737010600;57216652176;57209266195;57202712511;57216932703;57219029296; |
Insights Into Adolescents' Substance Use in a Low–Middle-Income Country During the COVID-19 Pandemic |
2021 |
Frontiers in Psychiatry |
12 |
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739698 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118257704&doi=10.3389%2ffpsyt.2021.739698&partnerID=40&md5=9b8aba71c0b6aaab6c7e81012e3c8927 |
Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Sen, L.T., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Siste, K., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Hanafi, E., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Murtani, B.J., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Christian, H., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Limawan, A.P., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Adrian, Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Siswidiani, L.P., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Introduction: The COVID-19 pandemic and its lockdown have been a significant life event for many individuals, particularly adolescents. The immense psychological pressure could drive risky behavior, e.g., substance use, while lockdown might lead to decreased use. This study aimed to observe the change in substance use among adolescents in Indonesia and the moderating variables to consumption during the COVID-19 lockdown period. Methods: This study utilized an online survey from April 28, 2020 to June 30, 2020. The hyperlink was disseminated to school administrators and parenting groups through social media and direct messages. A total of 2,932 adolescents (17.4 ± 2.24 and 78.7% females) submitted valid responses. The survey was comprised of a sociodemographic section, substance use details, and psychometric sections, including the Alcohol Use Disorders Identification Test (AUDIT), Cigarette Dependence Scale 12 (CDS-12), Pittsburgh Sleep Quality Index (PSQI), and Strength and Difficulties Questionnaire (SDQ). Results: Overall, adolescent alcohol use during the pandemic was 5.1%, cigarette smoking was 3.1%, and drug consumption was 0.4%. Over half (53.4%) of alcohol drinkers reported increased drinking, and 33.1% had harmful or dependence-like drinking behavior; in contrast, 44.4% of adolescent smokers disclosed reduced cigarette consumption. Around 37.8% of the drug users indicated increased use. During the pandemic, adolescent alcohol use was associated with higher education [adjusted odds ratio (AOR) = 2.67, 95% confidence interval (CI) 1.02–4.86, p = 0.04], higher AUDIT scores (AOR = 1.33, 95% CI 1.25–1.42, p < 0.001), and very low prosocial behavior (AOR = 2.46, 95% CI 1.52–3.88, p < 0.001). Cigarette smoking was correlated with male sex (AOR = 9.56, 95% CI 5.64–16.62, p < 0.001), age (AOR = 1.40, 95% CI 1.14–1.75, p < 0.001), and higher CDS score (AOR = 1.17, 95% CI 1.13–1.20, p < 0.001). Conclusions: Rates of adolescent substance use were significant, with sizeable proportions reporting higher usage. This appeared to occur predominantly in specific demographics and those with a lower protective psychosocial attribute, i.e., prosocial behavior, during the lockdown. These findings should urge the strengthening of adolescent addiction care during and after the pandemic. © Copyright © 2021 Sen, Siste, Hanafi, Murtani, Christian, Limawan, Adrian and Siswidiani. |
adolescent; alcohol; cigarette; COVID-19; drugs; Indonesia |
adolescent; Alcohol Use Disorders Identification Test; Article; Cigarette Dependence Scale 12; cigarette smoking; controlled study; coronavirus disease 2019; demography; descriptive research; educational status; female; health care survey; human; Indonesia; low income country; major clinical study; male; mental disease assessment; middle income country; online analysis; pandemic; Pittsburgh Sleep Quality Index; prevalence; prosocial behavior; psychometry; sex difference; social media; social status; Strength and Difficulties Questionnaire; substance use |
Frontiers Media S.A. |
16640640 |
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Article |
Q1 |
1363 |
2668 |
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119 |
Parikesit D., Adityagama M., Atmoko W., Birowo P., Taher A., Rasyid N. |
57163830300;57328473300;57193125664;6504153311;7005269743;56245069300; |
Reliability and validity of the Indonesian version of the aging males’ symptoms |
2021 |
Medical Journal of Indonesia |
30 |
3 |
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211 |
214 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118800087&doi=10.13181%2fmji.oa.215314&partnerID=40&md5=de2f7f19ff7768cc59e6ab7817803329 |
Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Urology, Faculty of Medicine, Universitas Indonesia, Universitas Indonesia Hospital, Depok, Indonesia |
Parikesit, D., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Department of Urology, Faculty of Medicine, Universitas Indonesia, Universitas Indonesia Hospital, Depok, Indonesia; Adityagama, M., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Atmoko, W., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Department of Urology, Faculty of Medicine, Universitas Indonesia, Universitas Indonesia Hospital, Depok, Indonesia; Birowo, P., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Taher, A., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rasyid, N., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
BACKGROUND Aging males’ symptoms (AMS) scale was developed to study the problems of aging males, especially related to the quality of life. Currently, there is no valid and reliable Indonesian version of the AMS scale. This study was aimed to translate and evaluate the validity and reliability of the Indonesian version of the AMS scale. METHODS This cross-sectional study translated the existing AMS scale into Indonesian, which was tested in 40 years old males from May to August 2020. Cross-cultural validation of the AMS scale was conducted by translating the questionnaire from English to Indonesian by two independent-certified translators. The validity of the Indonesian version of the AMS scale was measured by conducting a Pearson correlation (r) analysis. The reliability of this questionnaire was tested and retested in 118 participants with a 2-week interval. In addition, Cronbach’s alpha value was measured and used as a reference. The first test was conducted in a corporate blood donor event in Matraman, East Jakarta, and the retest was conducted in Cipto Mangunkusumo Hospital. RESULTS The Indonesian version of the AMS scale was valid and had a good internal consistency with a Cronbach’s alpha value of 0.74. The test-retest reliability showed good reliability with an r-value of 0.981. Pearson correlation test showed that all questions in the questionnaire were valid (p<0.05) and correlated positively. CONCLUSIONS The Indonesian version of the AMS scale derived from this study is valid and has good reliability. © 2021, Faculty of Medicine, Universitas Indonesia. All rights reserved. |
Aging males’ symptoms scale; Indonesian; Reliability and validity |
adult; aging; article; blood donor; Cronbach alpha coefficient; cross-sectional study; human; human experiment; internal consistency; language; major clinical study; male; questionnaire; test retest reliability; validity |
Faculty of Medicine, Universitas Indonesia |
08531773 |
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Article |
Q4 |
164 |
21905 |
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120 |
Soedarman S., Rahardjo H.E. |
57220581938;37762030000; |
Potential predictors of detrusor underactivity in a urology outpatient clinic: A 5-year single center experience study |
2021 |
Medical Journal of Indonesia |
30 |
3 |
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207 |
210 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118768336&doi=10.13181%2fmji.oa.215102&partnerID=40&md5=8286bb60fbc23a9907af0545c3ad23c0 |
Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Soedarman, S., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rahardjo, H.E., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
BACKGROUND Detrusor underactivity (DU) is diagnosed using urodynamics, which caused by a combination of strength and duration of the bladder muscle and resulted in prolonged bladder emptying. Invasive urodynamics, which are limited in many clinical settings, should be performed efficiently in high-risk patients to reduce the risk of emerging complications during and after the procedure. Therefore, this study was aimed to identify the potential predictors of DU for limited clinical settings. METHODS This retrospective study was retrieved from the medical records of patients who underwent urodynamics in the Department of Urology, Cipto Mangunkusumo Hospital from 2015 to 2020. Age, sex, bladder capacity, bladder compliance, bladder outlet obstruction, history of stroke, diabetes mellitus (DM) status, and neurological abnormalities were analyzed using chi-square and Mann–Whitney to examine the potential predictors of DU. The odds ratio (OR) of each factor was also calculated. Logistic regression was furtherly used for the analysis. RESULTS A total of 649 patients were included in this study. Male (OR = 1.74, 95% CI = 1.28–2.38) and DM patients (OR = 2.06, 95% CI = 1.36–3.11) had a higher risk of DU, while bladder outlet obstruction (OR = 0.54, 95% CI = 0.39–0.76) was the protective factor of DU. Furthermore, multivariate analysis showed that the potential predictors of DU were male (OR = 1.903, 95% CI = 1.37–2.64), DM (OR= 1.899, 95% CI = 1.22–2.95), and bladder outlet obstruction (OR = 0.32, 95% CI = 0.32–0.65). CONCLUSIONS Age, sex, bladder outlet obstruction, and history of DM could become the predictors of DU. © 2021, Faculty of Medicine, Universitas Indonesia. All rights reserved. |
Detrusor underactivity; Urinary bladder; Urodynamics |
adolescent; adult; age; aged; Article; bladder capacity; bladder compliance; bladder pressure; child; diabetes mellitus; diabetic patient; human; hypotonic bladder; major clinical study; male; neurologic disease; overactive bladder; sex; software; urodynamics |
Faculty of Medicine, Universitas Indonesia |
08531773 |
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Article |
Q4 |
164 |
21905 |
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