|
No records
|
|
118 |
Sen L.T., Siste K., Hanafi E., Murtani B.J., Christian H., Limawan A.P., Adrian, Siswidiani L.P. |
57219034101;55644113100;56737010600;57216652176;57209266195;57202712511;57216932703;57219029296; |
Insights Into Adolescents' Substance Use in a Low–Middle-Income Country During the COVID-19 Pandemic |
2021 |
Frontiers in Psychiatry |
12 |
|
739698 |
|
|
|
1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118257704&doi=10.3389%2ffpsyt.2021.739698&partnerID=40&md5=9b8aba71c0b6aaab6c7e81012e3c8927 |
Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Sen, L.T., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Siste, K., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Hanafi, E., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Murtani, B.J., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Christian, H., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Limawan, A.P., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Adrian, Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Siswidiani, L.P., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia—Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Introduction: The COVID-19 pandemic and its lockdown have been a significant life event for many individuals, particularly adolescents. The immense psychological pressure could drive risky behavior, e.g., substance use, while lockdown might lead to decreased use. This study aimed to observe the change in substance use among adolescents in Indonesia and the moderating variables to consumption during the COVID-19 lockdown period. Methods: This study utilized an online survey from April 28, 2020 to June 30, 2020. The hyperlink was disseminated to school administrators and parenting groups through social media and direct messages. A total of 2,932 adolescents (17.4 ± 2.24 and 78.7% females) submitted valid responses. The survey was comprised of a sociodemographic section, substance use details, and psychometric sections, including the Alcohol Use Disorders Identification Test (AUDIT), Cigarette Dependence Scale 12 (CDS-12), Pittsburgh Sleep Quality Index (PSQI), and Strength and Difficulties Questionnaire (SDQ). Results: Overall, adolescent alcohol use during the pandemic was 5.1%, cigarette smoking was 3.1%, and drug consumption was 0.4%. Over half (53.4%) of alcohol drinkers reported increased drinking, and 33.1% had harmful or dependence-like drinking behavior; in contrast, 44.4% of adolescent smokers disclosed reduced cigarette consumption. Around 37.8% of the drug users indicated increased use. During the pandemic, adolescent alcohol use was associated with higher education [adjusted odds ratio (AOR) = 2.67, 95% confidence interval (CI) 1.02–4.86, p = 0.04], higher AUDIT scores (AOR = 1.33, 95% CI 1.25–1.42, p < 0.001), and very low prosocial behavior (AOR = 2.46, 95% CI 1.52–3.88, p < 0.001). Cigarette smoking was correlated with male sex (AOR = 9.56, 95% CI 5.64–16.62, p < 0.001), age (AOR = 1.40, 95% CI 1.14–1.75, p < 0.001), and higher CDS score (AOR = 1.17, 95% CI 1.13–1.20, p < 0.001). Conclusions: Rates of adolescent substance use were significant, with sizeable proportions reporting higher usage. This appeared to occur predominantly in specific demographics and those with a lower protective psychosocial attribute, i.e., prosocial behavior, during the lockdown. These findings should urge the strengthening of adolescent addiction care during and after the pandemic. © Copyright © 2021 Sen, Siste, Hanafi, Murtani, Christian, Limawan, Adrian and Siswidiani. |
adolescent; alcohol; cigarette; COVID-19; drugs; Indonesia |
adolescent; Alcohol Use Disorders Identification Test; Article; Cigarette Dependence Scale 12; cigarette smoking; controlled study; coronavirus disease 2019; demography; descriptive research; educational status; female; health care survey; human; Indonesia; low income country; major clinical study; male; mental disease assessment; middle income country; online analysis; pandemic; Pittsburgh Sleep Quality Index; prevalence; prosocial behavior; psychometry; sex difference; social media; social status; Strength and Difficulties Questionnaire; substance use |
Frontiers Media S.A. |
16640640 |
|
|
Article |
Q1 |
1363 |
2668 |
|
|
|
122 |
Panigoro S.S., Sutandyo N., Witjaksono F., Siregar N.C., Ramli R., Hariani R., Pangarsa E.A., Prajoko Y.W., Puruhita N., Hamdani W., Bayu D., Madjid M., Yulidar D., Fransiska J.E., Widyawati R., Tripriadi E.S., Wiwit Ade F.W., Yunda D.K., Pranata R. |
56790104300;26028099200;57070455800;6508087790;56126010900;57211658330;57204907532;56050815500;57224902090;57211471316;57193199487;57311861300;57312306100;57197735128;57312525600;57312968000;57312306200;57312748700;57201973901; |
The Association Between Triglyceride-Glucose Index as a Marker of Insulin Resistance and the Risk of Breast Cancer |
2021 |
Frontiers in Endocrinology |
12 |
|
745236 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117891585&doi=10.3389%2ffendo.2021.745236&partnerID=40&md5=7c6ce4b0ece5dc9224c11aab644ae33c |
Department of Surgical Oncology, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Hematology and Medical Oncology, Dharmais Hospital National Cancer Center, Jakarta, Indonesia; Department of Nutrition, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Pathological Anatomy, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Surgical Oncology, Dharmais Hospital National Cancer Center, Jakarta, Indonesia; Department of Nutrition, Dharmais Hospital National Cancer Center, Jakarta, Indonesia; Department of Hematology and Medical Oncology, Dr. Kariadi General Hospital, Faculty of Medicine, Diponegoro University, Semarang, Indonesia; Department of Surgical Oncology, Dr. Kariadi General Hospital, Faculty of Medicine, Diponegoro University, Semarang, Indonesia; Department of Nutrition, Dr. Kariadi General Hospital, Faculty of Medicine, Diponegoro University, Semarang, Indonesia; Department of Surgical Oncology, Wahidin Sudirohusodo General Hospital, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia; Division of Hematology-Medical Oncology, Department of Internal Medicine, Hasanuddin University General Hospital, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia; Department of Nutrition, Faculty of Medicine, Wahidin Sudirohusodo General Hospital, Hasanuddin University, Makassar, Indonesia; Department of Surgical Oncology, Dr. WZ Johannes General Hospital, Kupang, Indonesia; Division of Hematology and Medical Oncology, Department of Internal Medicine, Dr. WZ Johannes General Hospital, Kupang, Indonesia; Department of Pathological Anatomy, Dr. WZ Johannes General Hospital, Kupang, Indonesia; Department of Surgical Oncology, Arifin Achmad General Hospital, Faculty of Medicine, Riau University, Pekanbaru, Indonesia; Department of Pathological Anatomy, Arifin Achmad General Hospital, Faculty of Medicine, Riau University, Pekanbaru, Indonesia; Department of Nutrition, Arifin Achmad General Hospital, Faculty of Medicine, Riau University, Pekanbaru, Indonesia; Department of Nutrition, Nutrition Cancer Reaserch Team, Dharmais Hospital National Cancer Center, Jakarta, Indonesia |
Panigoro, S.S., Department of Surgical Oncology, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Sutandyo, N., Department of Hematology and Medical Oncology, Dharmais Hospital National Cancer Center, Jakarta, Indonesia; Witjaksono, F., Department of Nutrition, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Siregar, N.C., Department of Pathological Anatomy, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Ramli, R., Department of Surgical Oncology, Dharmais Hospital National Cancer Center, Jakarta, Indonesia; Hariani, R., Department of Nutrition, Dharmais Hospital National Cancer Center, Jakarta, Indonesia; Pangarsa, E.A., Department of Hematology and Medical Oncology, Dr. Kariadi General Hospital, Faculty of Medicine, Diponegoro University, Semarang, Indonesia; Prajoko, Y.W., Department of Surgical Oncology, Dr. Kariadi General Hospital, Faculty of Medicine, Diponegoro University, Semarang, Indonesia; Puruhita, N., Department of Nutrition, Dr. Kariadi General Hospital, Faculty of Medicine, Diponegoro University, Semarang, Indonesia; Hamdani, W., Department of Surgical Oncology, Wahidin Sudirohusodo General Hospital, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia; Bayu, D., Division of Hematology-Medical Oncology, Department of Internal Medicine, Hasanuddin University General Hospital, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia; Madjid, M., Department of Nutrition, Faculty of Medicine, Wahidin Sudirohusodo General Hospital, Hasanuddin University, Makassar, Indonesia; Yulidar, D., Department of Surgical Oncology, Dr. WZ Johannes General Hospital, Kupang, Indonesia; Fransiska, J.E., Division of Hematology and Medical Oncology, Department of Internal Medicine, Dr. WZ Johannes General Hospital, Kupang, Indonesia; Widyawati, R., Department of Pathological Anatomy, Dr. WZ Johannes General Hospital, Kupang, Indonesia; Tripriadi, E.S., Department of Surgical Oncology, Arifin Achmad General Hospital, Faculty of Medicine, Riau University, Pekanbaru, Indonesia; Wiwit Ade, F.W., Department of Pathological Anatomy, Arifin Achmad General Hospital, Faculty of Medicine, Riau University, Pekanbaru, Indonesia; Yunda, D.K., Department of Nutrition, Arifin Achmad General Hospital, Faculty of Medicine, Riau University, Pekanbaru, Indonesia; Pranata, R., Department of Nutrition, Nutrition Cancer Reaserch Team, Dharmais Hospital National Cancer Center, Jakarta, Indonesia |
Background: This study aims to evaluate the association and dose-response between triglyceride-glucose (TyG) index and breast cancer. Method: This is a multicenter case-control study conducted in six public referral hospitals in Indonesia. Cases are individuals aged 19 years or above who were diagnosed with breast cancer within 1 year of diagnosis, based on histopathology and immunohistochemistry. Controls were recruited from corresponding hospitals. TyG index was determined by the formula: ln (fasting TG [mg/dl] × fasting glucose [mg/dl]). Results: There were 212 participants in the breast cancer group and 212 participants in the control group. TyG index was higher in patients with breast cancer (median 8.65 [7.38, 10.9] vs. 8.30 [7.09, 10.84], p < 0.001). When compared with TyG quartile of Q1, Q4 was associated with an OR of 2.42 (1.77, 3.31), p < 0.001, Q3 was associated with an OR of 1.53 (1.21, 1.93), p < 0.001, Q2 was associated with an OR of 1.39 (1.12, 1.73), p = 0.002 for the risk of breast cancer. The dose-response relationship was nonlinear (p < 0.001). On univariate analysis, smoking (OR 2.15 [1.44, 3.22], p < 0.001), use of contraception (1.73 [1.15, 2.60], p = 0.008), alcohol consumption (OR 2.04 [0.96, 4.35], p = 0.064), and TyG Index >8.87 (OR 3.08 [1.93, 4.93], p < 0.001) were associated with risk of breast cancer. Independently associated with increased risk of breast cancer included smoking (OR 1.93 [1.23, 3.01], p = 0.004), use of contraception (OR 1.59 [1.02, 2.48], p = 0.039), and TyG Index >8.87 (OR 2.93 [1.72, 4.98], p < 0.001) Conclusion: TyG index was associated with breast cancer in a nonlinear dose-response fashion. © Copyright © 2021 Panigoro, Sutandyo, Witjaksono, Siregar, Ramli, Hariani, Pangarsa, Prajoko, Puruhita, Hamdani, Bayu, Madjid, Yulidar, Fransiska, Widyawati, Tripriadi, F. W., Yunda and Pranata. |
breast cancer; glucose; insulin; insulin resistance; triglyceride |
insulin; triacylglycerol; adult; aged; alcohol consumption; Article; breast cancer; breast feeding; case control study; contraception; controlled study; dose response; female; glucose blood level; histopathology; human; human tissue; immunohistochemistry; major clinical study; multicenter study; nutrient uptake; obesity; questionnaire; smoking; triacylglycerol blood level; underweight; univariate analysis |
Frontiers Media S.A. |
16642392 |
|
|
Article |
Q1 |
1518 |
2233 |
|
|
|
134 |
Gamalliel N., Sutanto R.L., Wardhani A.N.H. |
57222183873;57222060277;57409481900; |
To involve or not to involve: youth participation in Indonesia's pandemic campaign |
2021 |
The Lancet Regional Health - Western Pacific |
15 |
|
100290 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85122707972&doi=10.1016%2fj.lanwpc.2021.100290&partnerID=40&md5=fd7cc1adaa04029c8ef04d93e3a955e5 |
National COVID-19 Volunteer, Indonesian Medical Students’ Executive Boards Association, Jakarta, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia |
Gamalliel, N., National COVID-19 Volunteer, Indonesian Medical Students’ Executive Boards Association, Jakarta, Indonesia, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Sutanto, R.L., National COVID-19 Volunteer, Indonesian Medical Students’ Executive Boards Association, Jakarta, Indonesia, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Wardhani, A.N.H., National COVID-19 Volunteer, Indonesian Medical Students’ Executive Boards Association, Jakarta, Indonesia, School of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia |
[No abstract available] |
|
|
Elsevier Ltd |
26666065 |
|
|
Note |
#N/A |
#N/A |
#N/A |
|
|
|
137 |
Aditianingsih D., Hidayat J., Ginting V.M. |
56312263600;57221444286;57377973500; |
Comparison of bioimpedance versus pulse contour analysis for intraoperative cardiac index monitoring in patients undergoing kidney transplantation |
2021 |
Anesthesiology and Pain Medicine |
11 |
5 |
e117918 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85121465922&doi=10.5812%2fAAPM.117918&partnerID=40&md5=cc44c95f4c7c6f8cc3dd0d4b279457ff |
Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia |
Aditianingsih, D., Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Hidayat, J., Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Ginting, V.M., Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia |
Background: Cardiac index (CI; cardiac output indexed to body surface area) is routinely measured during kidney transplant surgery. Bioimpedance cardiometry is a transthoracic impedance as the non-invasive alternative for hemodynamic monitoring, using semi-invasive uncalibrated pulse wave or contour (UPC) analysis. Objectives: We performed a cross-sectional observational study on 50 kidney transplant patients to compare the CI measurement agreement, concordance rate, and trending ability between bioimpedance and UPC analysis. Methods: For each patient, CI was measured by bioimpedance analysis (ICON™) and UPC analysis (EV1000™) devices at three time points: after induction, during incision, and at reperfusion. The device measurement accuracy was assessed by the bias value, limit of agreement (LoA), and percentage error (PE) using Bland-Altman analyses. Trending ability was assessed by angular bias and polar concordance through four-quadrant and polar plot analyses. Results: From each time point and pooled measurement, the correlation coefficients were 0.267, 0.327, 0.321, and 0.348. BlandAltman analyses showed mean bias values of 1.18, 1.06, 1.48, and 1.30, LoA of-1.35 to 3.72,-1.39 to 3.51,-1.07 to 4.04, and-1.17 to 3.78, and PE of 82.21, 78.50, 68.74, and 74.58%, respectively. Polar plot analyses revealed angular bias values of-10.37º,-15.01º,-18.68º, and-12.62º, with radial LoA of 89.79º, 85.86º, 83.38º, and 87.82º, respectively. The four-quadrant plot concordance rates were 70.77, 67.35, 65.90, and 69.79%. These analyses showed poor agreement, weak concordance, and low trending ability of bioimpedance cardiometry to UPC analysis. Conclusions: Bioimpedance and UPC analysis for CI measurements were not interchangeable in patients undergoing kidney transplant surgery. Cardiac index monitoring using bioimpedance cardiometry during kidney transplantation should be interpreted cautiously because it showed poor reliability due to low accuracy, precision, and trending ability for CI measurement. © 2021, Author(s). |
Cardiac Output; Intraoperative Monitoring; Kidney Transplantation; Pulse Wave Analysis; Transthoracic Impedance |
atracurium besilate; dobutamine; fentanyl; noradrenalin; propofol; sevoflurane; adult; aged; agitation; anesthesia induction; arterial pressure; Article; body mass; bradycardia; cardiac index; cardiopulmonary bypass; central venous pressure; chronic kidney failure; correlation coefficient; cross-sectional study; female; heart arrhythmia; heart output; heart rate; heart stroke volume; hemodynamic monitoring; human; hypertension; intraoperative monitoring; kidney transplantation; major clinical study; male; mean arterial pressure; measurement accuracy; nausea and vomiting; observational study; outcome assessment; pleura effusion; prospective cost; prospective study; pulse oximetry; pulse wave; systolic blood pressure; tachycardia; transesophageal echocardiography; uncalibrated pulse contour |
Kowsar Medical Institute |
22287523 |
|
|
Article |
Q2 |
438 |
11251 |
|
|
|
140 |
Waters S., Agostino M., Lee S., Ariyanto I., Kresoje N., Leary S., Munyard K., Gaudieri S., Gaff J., Irish A., Keil A.D., Price P., Allcock R.J.N. |
57195514207;34771068500;56272877300;57193538110;55413004800;56906725500;6506851062;56245970200;57193534280;7004314741;57339623900;57201814264;7003764659; |
Sequencing directly from clinical specimens reveals genetic variations in HCMV-encoded chemokine receptor us28 that may influence antibody levels and interactions with human chemokines |
2021 |
Microbiology Spectrum |
9 |
2 |
e00020-21 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119150219&doi=10.1128%2fSpectrum.00020-21&partnerID=40&md5=d943d30d66f9a7de80628f87fcbb3810 |
Curtin Medical School, Curtin Health Innovation Research Institute, Curtin University, Bentley, WA, Australia; Curtin Institute for Computation, Curtin University, Bentley, WA, Australia; Department of Microbiology, PathWest Laboratory Medicine WA, Nedlands, WA, Australia; Virology and Cancer Pathobiology Research Center, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; School of Biomedical Sciences, University of Western Australia, Perth, WA, Australia; Institute for Immunology and Infectious Diseases, Murdoch University, Murdoch, WA, Australia; School of Human Sciences, University of Western Australia, Perth, WA, Australia; Department of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, United States; Department of Nephrology, Fiona Stanley Hospital, Murdoch, WA, Australia; Department of Diagnostic Genomics, PathWest Laboratory Medicine WA, Nedlands, WA, Australia |
Waters, S., Curtin Medical School, Curtin Health Innovation Research Institute, Curtin University, Bentley, WA, Australia; Agostino, M., Curtin Medical School, Curtin Health Innovation Research Institute, Curtin University, Bentley, WA, Australia, Curtin Institute for Computation, Curtin University, Bentley, WA, Australia; Lee, S., Curtin Medical School, Curtin Health Innovation Research Institute, Curtin University, Bentley, WA, Australia, Department of Microbiology, PathWest Laboratory Medicine WA, Nedlands, WA, Australia; Ariyanto, I., Virology and Cancer Pathobiology Research Center, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Kresoje, N., School of Biomedical Sciences, University of Western Australia, Perth, WA, Australia; Leary, S., Institute for Immunology and Infectious Diseases, Murdoch University, Murdoch, WA, Australia; Munyard, K., Curtin Medical School, Curtin Health Innovation Research Institute, Curtin University, Bentley, WA, Australia; Gaudieri, S., Institute for Immunology and Infectious Diseases, Murdoch University, Murdoch, WA, Australia, School of Human Sciences, University of Western Australia, Perth, WA, Australia, Department of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, United States; Gaff, J., Curtin Medical School, Curtin Health Innovation Research Institute, Curtin University, Bentley, WA, Australia; Irish, A., Department of Nephrology, Fiona Stanley Hospital, Murdoch, WA, Australia; Keil, A.D., Department of Microbiology, PathWest Laboratory Medicine WA, Nedlands, WA, Australia; Price, P., Curtin Medical School, Curtin Health Innovation Research Institute, Curtin University, Bentley, WA, Australia; Allcock, R.J.N., School of Biomedical Sciences, University of Western Australia, Perth, WA, Australia, Department of Diagnostic Genomics, PathWest Laboratory Medicine WA, Nedlands, WA, Australia |
Human cytomegalovirus (HCMV) is a beta-herpesvirus carried by;80% of the world’s population. Acute infections are asymptomatic in healthy individuals but generate diverse syndromes in neonates, solid organ transplant recipients, and HIV-infected individuals. The HCMV gene US28 encodes a homolog of a human chemokine receptor that is able to bind several chemokines and HIV gp120. Deep sequencing technologies were used to sequence US28 directly from 60 clinical samples from Indonesian HIV patients and Australian renal transplant recipients, healthy adults, and neonates. Molecular modeling approaches were used to predict whether nine nonsynonymous mutations in US28 may alter protein binding to a panel of six chemokines and two variants of HIV gp120. Ninety-two percent of samples contained more than one variant of HCMV, as defined by at least one nonsynonymous mutation. Carriage of these variants differed between neonates and adults, Australian and Indonesian samples, and saliva samples and blood leukocytes. Two nonsynonymous mutations (N170D and R267K) were associated with increased levels of immediate early protein 1 (IE-1) and glycoprotein B (gB) HCMV-reactive antibodies, suggesting a higher viral burden. Seven of the nine mutations were predicted to alter binding of at least one ligand. Overall, HCMV variants are common in all populations and have the potential to affect US28 interactions with human chemokines and/or gp120 and alter responses to the virus. The findings relied on deep sequencing technologies applied directly to clinical samples, so the variants exist in vivo. IMPORTANCE Human cytomegalovirus (HCMV) is a common viral pathogen of solid organ transplant recipients, neonates, and HIV-infected individuals. HCMV encodes homologs of several host genes with the potential to influence viral persistence and/ or pathogenesis. Here, we present deep sequencing of an HCMV chemokine receptor homolog, US28, acquired directly from clinical specimens. Carriage of these variants differed between patient groups and was associated with different levels of circulating HCMV-reactive antibodies. These features are consistent with a role for US28 in HCMV persistence and pathogenesis. This was supported by in silico analyses of the variant sequences demonstrating altered ligand-binding profiles. The data delineate a novel approach to understanding the pathogenesis of HCMV and may impact the development of an effective vaccine. Copyright © 2021 Waters et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license. |
Chemokine receptor; Deep sequencing; HIV patients; Human cytomegalovirus; Renal transplant recipients; US28 |
arginine; asparagine; aspartic acid; chemokine; chemokine receptor; chemokine receptor US28; glycoprotein B; glycoprotein gp 120; immediate early protein; immediate early protein 1; lysine; unclassified drug; virus antibody; chemokine; chemokine receptor; protein binding; US28 receptor, Cytomegalovirus; viral protein; virus antibody; adult; Article; Australian; blood; controlled study; genetic variation; graft recipient; human; Human cytomegalovirus; Human immunodeficiency virus infection; Indonesian; kidney transplantation; leukocyte; molecular model; mutation; newborn; nonhuman; protein protein interaction; saliva; virus load; amino acid sequence; blood; Cytomegalovirus; cytomegalovirus infection; genetic variation; genetics; high throughput sequencing; immunology; infant; isolation and |
American Society for Microbiology |
21650497 |
|
34704798 |
Article |
Q1 |
2502 |
907 |
|
|
|
144 |
Susiloretni K.A., Smith E.R., Suparmi, Marsum, Agustina R., Shankar A.H. |
55920057100;55479658700;57201388096;57203690495;57214141404;7005442634; |
The psychological distress of parents is associated with reduced linear growth of children: Evidence from a nationwide population survey |
2021 |
PLoS ONE |
16 |
10 October |
e0246725 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118229642&doi=10.1371%2fjournal.pone.0246725&partnerID=40&md5=e63e172d790e5a4d43ab7ba273dd42d6 |
Semarang Health Polytechnic Ministry of Health - Poltekkes Kemenkes Semarang, Central Java, Semarang, Indonesia; Department of Global Health, George Washington University, Washington, D.C., United States; National Health Institute Research and Development, Jakarta, Indonesia; Faculty of Medicine, Department of Nutrition, Universitas Indonesia – Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Faculty of Medicine, Human Nutrition Research Center, Indonesian Medical Education and Research Institute, Universitas Indonesia, Jakarta, Indonesia; Eijkman-Oxford Clinical Research Unit, Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Nuffield Department of Medicine, The Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom |
Susiloretni, K.A., Semarang Health Polytechnic Ministry of Health - Poltekkes Kemenkes Semarang, Central Java, Semarang, Indonesia; Smith, E.R., Department of Global Health, George Washington University, Washington, D.C., United States; Suparmi, National Health Institute Research and Development, Jakarta, Indonesia; Marsum, Semarang Health Polytechnic Ministry of Health - Poltekkes Kemenkes Semarang, Central Java, Semarang, Indonesia; Agustina, R., Faculty of Medicine, Department of Nutrition, Universitas Indonesia – Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia, Faculty of Medicine, Human Nutrition Research Center, Indonesian Medical Education and Research Institute, Universitas Indonesia, Jakarta, Indonesia; Shankar, A.H., Eijkman-Oxford Clinical Research Unit, Eijkman Institute for Molecular Biology, Jakarta, Indonesia, Nuffield Department of Medicine, The Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, United Kingdom |
Background Stunting, an indicator of restricted linear growth, has become a primary measure of childhood undernutrition due to its persistent high prevalence globally, and importance for health and development. Although the etiology is recognized as complex, most analyses have focused on social and biomedical determinants, with limited attention on psychological factors affecting care and nurturing in the home. We assessed whether the psychological distress of parents is related to child linear growth and stunting, and documented the associated risk factors, and examined the relationship between parental distress and behavioral and other risk factors for stunting. Methods We used data from the Indonesia National Health Survey 2013, including 46,315 children 6–59 months of age. Multivariate linear, logistic, and multilevel multinomial logistic regression, using survey weights, were used to assess the relationship between parental distress, as assessed by the WHO Self Reporting Questionnaire (SRQ20), with height-for-age z score (HAZ), stunting, and behavioral and other risk factors for stunting. Results Maternal, paternal and parental distress (i.e. both maternal and paternal distress) were associated with reduced linear growth of the children by 0.086 (95% CI -0.17, -0.00), 0.11 (95% CI -0.24, -0.02) and 0.19 (95% CI -0.37, -0.00) HAZ-scores, respectively. Maternal and paternal distress increased the risk of mild stunting (HAZ <-1) by 33% (95% CI 1.17,1.50) and 37% (95% CI 1.18,1.60), and the risk of moderate stunting (HAZ <-2) by 25% (95% CI 1.10,1.43) and 28% (95% CI 1.08,1.51]), respectively. Parental stress increased the risk of moderate stunting by 40% (95% CI 1.06,1.85). Amongst specific groups of risk factors, the proportion of HAZ-score lost was associated with socioeconomic factors (30.3%) including, low wealth, low maternal occupational status, low maternal education, rural residence, and low paternal occupational status; physiological factors (15.5%) including low maternal height, low maternal mid-upper arm circumference, being male, low paternal height; behavioral factors (8.9%) including open garbage disposal, paternal smoking, not using iodized salt; and experiencing at least one infectious diseases episode (1.1%). Conclusions Maternal, paternal and parental stress were associated with reduced linear growth of children. These findings highlight the complex etiology of stunting and suggest nutritional and other biomedical interventions are insufficient, and that promotion of mental and behavioral health programs for parents must be pursued as part of a comprehensive strategy to enhance child growth and development, i.e. improved caretaker capacity, integrated community development, improved parenting skills, as well as reduced gender discrimination, and domestic violence. © 2021 Susiloretni et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
|
sodium chloride; adult; anthropometric parameters; arm circumference; Article; body height; child; child development; child growth; child parent relation; distress syndrome; domestic violence; education; female; health behavior; health program; health survey; height for age z score; human; Indonesia; infant; infection; male; maternal stress; multivariate logistic regression analysis; occupation; parental stress; paternal smoking; paternal stress; physiology; population; risk factor; rural area; Self Reporting Questionnaire 20; sex ratio; sexism; socioeconomics; stunting; waste disposal; wealth distribution; cross-sectional study; distress syndrome; educational status; growth disorder; nutritional status; physiology; preschool child; prevalence; psychology; rural population; Body Height; Ch |
Public Library of Science |
19326203 |
|
34699530 |
Article |
Q1 |
990 |
4434 |
|
|
|
148 |
Patelis N., Bisdas T., Jing Z., Feng J., Trenner M., Tri Nugroho N., Reis P.E.O., Elkouri S., Lecis A., Karam L., Roux D.L., Ionac M., Berczeli M., Jongkind V., Yeung K.K., Katsargyris A., Avgerinos E., Moris D., Choong A., Ng J.J., Cvjetko I., Antoniou G.A., Ghibu P., Svetlikov A., Pedrajas F.G., Ebben H.P., Stepak H., Chornuy A., Kostiv S., Ancetti S., Tadayon N., Mekkar A., Magnitskiy L., Fidalgo-Domingos L., Matheiken S., Rosello E.S.S., Isik A., Kirkilesis G., Kakavia K., Georgopoulos S. |
55998488300;33467522500;57262125800;57261537000;56798307500;57211452795;56682147200;6604020673;55309720700;36504221700;57261537100;57262413400;57204192771;22937335300;57288124100;15923092600;6701829526;39661222400;57217303517;57226512691;7801457268;36086125600;57261833900;6508177128;6504474654;56115588600;55760251500;57262413500;57222182796;56703428400;35182045900;57261687200;57262413600;57197759620;36834063300;57287572100;57159146500;56201755100;57191724932;7003934555; |
Dataset of the vascular e-Learning during the COVID-19 pandemic (EL-COVID) survey |
2021 |
Data in Brief |
38 |
|
107442 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116548448&doi=10.1016%2fj.dib.2021.107442&partnerID=40&md5=13eed264f7fe81ba580e470c82209330 |
3rd Department of Vascular Surgery, Athens Medical Center, Greece; National & Kapodistrian University of Athens, Greece; Vascular surgery department, First affiliated hospital to Navy medical university, Shanghai, China; Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Germany; Faculty of Medicine University of Indonesia - Cipto Mangunkusumo National Hospital, Indonesia; Federal University Fluminense, Brazil; Centre Hospitalier de l'Université de Montréal, Canada; Centre Hospitalier de Troyes, France; Hotel Dieu de France Hospital, Lebanon; University of the Witwatersrand, South Africa; University of Medicine and Pharmacy, Romania; Semmelweis University, Hungary; Amsterdam University Medical Center, Netherlands; VU Medical Center, Netherlands; Paracelsus Medical University, Klinikum Nurenberg, Germany; University of Pittsburgh Medical Center, United States; Duke University Medical Center, United States; National University of Singapore, Singapore; University Hospital Merkur, Croatia; Pennine Acute Hospitals NHS TrustUK, United Kingdom; University Hospital HairmyresUK, United Kingdom; Vascular & endovascular surgery Center, National Scientific-Clinical Memorial Hospital, ``Professor I.I. Mechnikov'', North-Western Medical University, Russian Federation; Hospital Quironsalud Málaga, Spain; Poznan University of Medical Sciences, Poland; Ternopil University Clinic, Ukraine; University of Bologna, Italy; Shahid Beheshti University of Medical Sciences, Iran; CHU Titi Ouzou, Algeria; Pirogov City Hospital No1, Russian Federation; Hospital Clínico Universitario de Valladolid, Spain; Bedford Hospital NHS TrustUK, United Kingdom; Universidad de la Republica, Uruguay; Erzincan Binali Yildirim University, Turkey |
Patelis, N., 3rd Department of Vascular Surgery, Athens Medical Center, Greece, National & Kapodistrian University of Athens, Greece; Bisdas, T., 3rd Department of Vascular Surgery, Athens Medical Center, Greece; Jing, Z., Vascular surgery department, First affiliated hospital to Navy medical university, Shanghai, China; Feng, J., Vascular surgery department, First affiliated hospital to Navy medical university, Shanghai, China; Trenner, M., Klinikum rechts der Isar, School of Medicine, Technical University of Munich, Germany; Tri Nugroho, N., Faculty of Medicine University of Indonesia - Cipto Mangunkusumo National Hospital, Indonesia; Reis, P.E.O., Federal University Fluminense, Brazil; Elkouri, S., Centre Hospitalier de l'Université de Montréal, Canada; Lecis, A., Centre Hospitalier de Troyes, France; Karam, L., Hotel Dieu de France Hospital, Lebanon; Roux, D.L., University of the Witwatersrand, South Africa; Ionac, M., University of Medicine and Pharmacy, Romania; Berczeli, M., Semmelweis University, Hungary; Jongkind, V., Amsterdam University Medical Center, Netherlands; Yeung, K.K., VU Medical Center, Netherlands; Katsargyris, A., National & Kapodistrian University of Athens, Greece, Paracelsus Medical University, Klinikum Nurenberg, Germany; Avgerinos, E., National & Kapodistrian University of Athens, Greece, University of Pittsburgh Medical Center, United States; Moris, D., Duke University Medical Center, United States; Choong, A., National University of Singapore, Singapore; Ng, J.J., National University of Singapore, Singapore; Cvjetko, I., University Hospital Merkur, Croatia; Antoniou, G.A., Pennine Acute Hospitals NHS TrustUK, United Kingdom; Ghibu, P., University Hospital HairmyresUK, United Kingdom; Svetlikov, A., University Hospital HairmyresUK, United Kingdom; Pedrajas, F.G., Vascular & endovascular surgery Center, National Scientific-Clinical Memorial Hospital, ``Professor I.I. Mechnikov'', North-Western Medical University, Russian Federation; Ebben, H.P., Hospital Quironsalud Málaga, Spain; Stepak, H., Poznan University of Medical Sciences, Poland; Chornuy, A., Ternopil University Clinic, Ukraine; Kostiv, S., Ternopil University Clinic, Ukraine; Ancetti, S., University of Bologna, Italy; Tadayon, N., Shahid Beheshti University of Medical Sciences, Iran; Mekkar, A., CHU Titi Ouzou, Algeria; Magnitskiy, L., Pirogov City Hospital No1, Russian Federation; Fidalgo-Domingos, L., Hospital Clínico Universitario de Valladolid, Spain; Matheiken, S., Bedford Hospital NHS TrustUK, United Kingdom; Rosello, E.S.S., Universidad de la Republica, Uruguay; Isik, A., Erzincan Binali Yildirim University, Turkey; Kirkilesis, G., National & Kapodistrian University of Athens, Greece; Kakavia, K., National & Kapodistrian University of Athens, Greece; Georgopoulos, S., National & Kapodistrian University of Athens, Greece |
This dataset supports the findings of the vascular e-Learning during the COVID-19 pandemic survey (the EL-COVID survey). The General Data Protection Regulation (GDPR) of the European Union was taken into consideration in all steps of data handling. The survey was approved by the institutional ethics committee of the Primary Investigator and an online English survey consisting of 18 questions was developed ad-hoc. A bilingual English-Mandarin version of the questionnaire was developed according to the instructions of the Chinese Medical Association in order to be used in mainland People's Republic of China. Differences between the two questionnaires were minor and did affect the process of data collection. Both questionnaires were hosted online. The EL-COVID survey was advertised through major social media. All national and regional contributors contacted their respective colleagues through direct messaging on social media or by email. Eight national societies or groups supported the dissemination of the EL-COVID survey. The data provided demographics information of the EL-COVID participants and an insight on the level of difficulty in accessing or citing previously attended online activities and whether participants were keen on citing these activities in their Curricula Vitae. A categorization of additional comments made by the participants are also based on the data. The survey responses were filtered, anonymized and submitted to descriptive analysis of percentage. © 2021 |
Distance learning; e-learning; Education; Surgery; Training; Vascular surgery |
|
Elsevier Inc. |
23523409 |
|
|
Data Paper |
Q4 |
122 |
26738 |
|
|
|
149 |
Mirza H., Rahmadi R. |
57208513330;57212589074; |
Peyronie disease: Our first experience with Ducket Baskin tunica albuginea plication (TAP) technique |
2021 |
International Journal of Surgery Case Reports |
87 |
|
106451 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116436763&doi=10.1016%2fj.ijscr.2021.106451&partnerID=40&md5=84094d95d09430b0098354a4215d5688 |
Division of Urology, Department of Surgery, Persahabatan Hospital, Indonesia; Department of Urology, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Mirza, H., Division of Urology, Department of Surgery, Persahabatan Hospital, Indonesia; Rahmadi, R., Department of Urology, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Introduction: Peyronie's Disease is a deformity of the penis. Surgical procedure options for Peyronie's disease treatment include grafting (curvature >60°) or plication (curvature <60°). This case report emphasizes the curvature degree and therapy options chosen, such as tunica albuginea plication instead of grafting. Case presentation: A 55-year-old male complains about a curved penis during erection. Examination shows penile bending 70° ventrally with ±15 cm length and 2x4cm size. The patient underwent Ducket-Baskin tunica albuginea placation (TAP). Postoperative unbent penis size decrement of ±3 cm, neither pain nor erectile dysfunction felt. Clinical discussion: Tunica plication is usually recommended in Peyronie's disease patients with curvature less than 60°, without an hourglass or hinge if grafting is not available. This technique is more simple, safe, the higher success rate of curvature correction (> 80%), low recurrency, low complication rate of penile hypoesthesia (approximately 10%), as well as low risk for postoperative erectile dysfunction. Conclusion: In our case, the tunica albuginea plication technique gives a good outcome in Peyronie's disease reconstruction. © 2021 The Authors |
Ducket-Baskin; Penile curvature; Penile deformity; Peyronie disease; Tunica albuginea plication |
adult; Article; case report; clinical article; conservative treatment; corpus cavernosum; diabetes mellitus; ducket baskin tunica albuginea placation; echography; erectile dysfunction; follow up; hospital admission; human; hypertension; male; male genital tract parameters; middle aged; pain; penis erection; penis length; Peyronie disease; physical examination; sexual intercourse; smoking; tunica albuginea; unbent penis size decrement |
Elsevier Ltd |
22102612 |
|
|
Article |
Q3 |
232 |
17549 |
|
|
|
150 |
Basrowi R.W., Rahayu E.M., Khoe L.C., Wasito E., Sundjaya T. |
57024210400;57275241200;56586245200;6506940239;57188810826; |
The road to healthy ageing: What has indonesia achieved so far? |
2021 |
Nutrients |
13 |
10 |
3441 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115825022&doi=10.3390%2fnu13103441&partnerID=40&md5=71597249210e18c8c5775dcf67e18dbe |
Occupational Medicine Division, Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Medical and Science Affairs Division, Danone Specialized Nutrition Indonesia, Jakarta, 12950, Indonesia; Department of Anthropology, Faculty of Social and Political Science Universitas Indonesia, Depok, 16424, Indonesia; Laboratorium Political Psychology, Faculty of Psychology Universitas Indonesia, Depok, 16424, Indonesia |
Basrowi, R.W., Occupational Medicine Division, Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Medical and Science Affairs Division, Danone Specialized Nutrition Indonesia, Jakarta, 12950, Indonesia; Rahayu, E.M., Department of Anthropology, Faculty of Social and Political Science Universitas Indonesia, Depok, 16424, Indonesia, Laboratorium Political Psychology, Faculty of Psychology Universitas Indonesia, Depok, 16424, Indonesia; Khoe, L.C., Occupational Medicine Division, Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Wasito, E., Medical and Science Affairs Division, Danone Specialized Nutrition Indonesia, Jakarta, 12950, Indonesia; Sundjaya, T., Medical and Science Affairs Division, Danone Specialized Nutrition Indonesia, Jakarta, 12950, Indonesia |
The World Health Organization (WHO) has projected that the world should prepare for an aging society. As the fourth most populous country in the world, the elderly population in Indonesia is also continuously growing. In 2010, the proportion of the elderly group was merely 5%, and it is expected to increase to 11% in 2035. Understanding the current situation of the adult population in Indonesia would be crucial to prepare for the future aging population. This article analyzed the current socio-demographic status, nutrition status, nutrient intake, and health profile of the current Indonesian adult population through a literature review. The key issues to prepare for healthy aging in Indonesia are summarized. Acknowledging the profile of the adult and senior adult population in Indonesia will provide beneficial information for all stakeholders in preparing Indonesia for a better healthy aging population with improved quality of life. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Aging population; Demographic; Health profile; Healthy ageing; Nutritional status |
adult; aged; demography; female; healthy aging; human; human experiment; Indonesia; Indonesian; male; nutrient intake; nutritional status; quality of life; review; World Health Organization; epidemiology; health status; health survey; Indonesia; nutritional status; socioeconomics; Health Status; Healthy Aging; Humans; Indonesia; Nutritional Status; Public Health Surveillance; Quality of Life; Socioeconomic Factors |
MDPI |
20726643 |
|
34684441 |
Review |
Q1 |
1418 |
2497 |
|
|
|
151 |
Erwin U.S., Cahyadi S.D. |
57216822223;57270709000; |
Total elbow arthroplasty as a reconstruction option for distal humerus osteosarcoma: A case report |
2021 |
International Journal of Surgery Case Reports |
87 |
|
106392 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115606771&doi=10.1016%2fj.ijscr.2021.106392&partnerID=40&md5=0a0870e6be133daae5f326c3ac0989f8 |
Department of Orthopaedic and Traumatology, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Indonesia; Department of Orthopaedic and Traumatology, Faculty of Medicine Universitas Indonesia, Persahabatan General Hospital, Indonesia |
Erwin, U.S., Department of Orthopaedic and Traumatology, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Indonesia; Cahyadi, S.D., Department of Orthopaedic and Traumatology, Faculty of Medicine Universitas Indonesia, Persahabatan General Hospital, Indonesia |
Introduction: Osteosarcoma is the second most common malignant bone tumor. The humerus is the third most common anatomical location for osteosarcoma, however, osteosarcoma around the elbow joint is uncommon. The intricacy of the elbow joint, limited soft tissue coverage, and proximity to nerves and arteries make the surgical resection and reconstruction complicated. Case report: A 17-year-old boy came with a chief complaint of lump and pain on his left elbow. One month later, the patient felt there was a lump with a size of a marble on the left elbow, which getting bigger to a size of a tenis ball. Physical examination showed mass on the posterior aspect of the elbow with the size 14x12cm. Plain radiographs revealed osteolytic lesion and periosteal reaction of the distal humerus and the magnetic resonance imaging (MRI) showed a low intensity on T2-weighted imaging. Histopathological examination suggested osteosarcoma. The patient underwent neoadjuvant chemotherapy for 3 cycles. The patient was treated with limb salvage surgery by wide excision, cryosurgery followed by total elbow arthroplasty and ORIF with plate and screw. Postoperative plain radiographs showed the plate and screws are well-fixated. The patient can slowly regain his elbow motion without limitation one month postoperatively. Conclusions: Distal humerus in an unusual site for osteosarcoma. Total elbow arthroplasty and ORIF with plate and screw is a favorable reconstruction option for distal humerus osteosarcoma with excellent postoperative functional outcomes. © 2021 The Authors |
Distal humerus; Osteosarcoma; Total elbow arthroplasty |
cisplatin; doxorubicin; ifosfamide; liquid nitrogen; adolescent; arthralgia; Article; bone atrophy; bone radiography; case report; clinical article; computer assisted tomography; debridement; distal humerus; elbow arthroplasty; general anesthesia; histopathology; human; joint radiography; limb salvage; male; multiple cycle treatment; neoadjuvant chemotherapy; nuclear magnetic resonance imaging; osteosarcoma; osteotomy; periosteum; physical examination; postoperative care; radial artery; radial nerve; range of motion; reconstructive surgery; room temperature; total arthroplasty; ulnar nerve |
Elsevier Ltd |
22102612 |
|
|
Article |
Q3 |
232 |
17549 |
|
|
