457 |
Rozaliyani A., Setianingrum F., Azahra S., Abdullah A., Fatril A.E., Rosianawati H., Burhan E., Handayani D., Arifin A.R., Zaini J., Tugiran M., Adawiyah R., Syam R., Wibowo H., Wahyuningsih R., Kosmidis C., Denning D.W. |
57203065912;57203061705;57219977463;57223138415;57223130315;57220203100;36058554600;57219413838;57223139966;57221833355;57218291154;57208658742;57218290535;57217690943;6507268400;16834840500;57223404509; |
Performance of ldbio aspergillus wb and ict antibody detection in chronic pulmonary aspergillosis |
2021 |
Journal of Fungi |
7 |
4 |
311 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105015900&doi=10.3390%2fjof7040311&partnerID=40&md5=d403a899e390ae45f6c1071eeb2d4832 |
Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, 13230, Indonesia; MH Thamrin Hospital, Jakarta, 10440, Indonesia; Department of Parasitology, Faculty of Medicine, Universitas Kristen, Jakarta, 13530, Indonesia; Manchester Academic Health Science Centre, Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, School of Biological Sciences, Medicine and Health, University of Manchester, Manchester, M23 9LT, United Kingdom |
Rozaliyani, A., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Setianingrum, F., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Azahra, S., Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Abdullah, A., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Fatril, A.E., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Rosianawati, H., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, 13230, Indonesia; Burhan, E., Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia, Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, 13230, Indonesia; Handayani, D., Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia, Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, 13230, Indonesia; Arifin, A.R., Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia, MH Thamrin Hospital, Jakarta, 10440, Indonesia; Zaini, J., Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia, Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, 13230, Indonesia; Tugiran, M., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Adawiyah, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Syam, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Wibowo, H., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Wahyuningsih, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia, Department of Parasitology, Faculty of Medicine, Universitas Kristen, Jakarta, 13530, Indonesia; Kosmidis, C., Manchester Academic Health Science Centre, Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, School of Biological Sciences, Medicine and Health, University of Manchester, Manchester, M23 9LT, United Kingdom; Denning, D.W., Manchester Academic Health Science Centre, Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, School of Biological Sciences, Medicine and Health, University of Manchester, Manchester, M23 9LT, United Kingdom |
The detection of Aspergillus antibody has a key role in the diagnosis of chronic pulmonary as-pergillosis. Western blot (WB) and immunochromatography (ICT) lateral flow detection of Aspergillus antibody can be used as confirmatory and screening assays but their comparative performance in TB patients is not known. This study investigated the performance of these assays among 88 post-tuberculosis patients with suspected CPA. Sensitivity, specificity, receiver operating curve (ROC), area under-curve (AUC) and the agreement between two assays were evaluated. Both WB and ICT showed good sensitivity (80% and 85%, respectively) for detection of Aspergillus antibodies. Substantial agreement (0.716) between these assays was also obtained. The highest AUC result (0.804) was achieved with the combination of WB and ICT. The global intensity of WB correlated with the severity of symptoms in CPA group (p = 0.001). The combination of WB and ICT may increase specificity in CPA diagnosis. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Chronic pulmonary aspergillosis; Immunochromatography; Western blot |
|
MDPI AG |
2309608X |
|
|
Article |
Q1 |
1702 |
1800 |
|
|