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271 |
Yonas E., Alwi I., Pranata R., Huang I., Lim M.A., Gutierrez E.J., Yamin M., Siswanto B.B., Virani S.S. |
57201987097;15055173800;57201973901;57208576645;57216039756;57200435964;23475706300;14422648800;6701757915; |
Effect of heart failure on the outcome of COVID-19 — A meta analysis and systematic review |
2021 |
American Journal of Emergency Medicine |
46 |
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204 |
211 |
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43 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85090893264&doi=10.1016%2fj.ajem.2020.07.009&partnerID=40&md5=08c8139ca7f811f915c445cf5c2e3f1c |
Faculty of Medicine, Universitas YARSI, Jakarta, Indonesia; Division of Cardiology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Department of Critical Care Medicine, Baptist Medical Center, Jacksonville, FL, United States; Department of Cardiology and Vascular Medicine, Faculty of Medicine Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Michael E. DeBakey Veterans Affairs Medical Center & Baylor College of Medicine, Houston, TX, United States; Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran, Hasan Sadikin General Hospital, Bandung, Indonesia, Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia |
Yonas, E., Faculty of Medicine, Universitas YARSI, Jakarta, Indonesia; Alwi, I., Division of Cardiology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Pranata, R., Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Huang, I., Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran, Hasan Sadikin General Hospital, Bandung, Indonesia, Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Lim, M.A., Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Gutierrez, E.J., Department of Critical Care Medicine, Baptist Medical Center, Jacksonville, FL, United States; Yamin, M., Division of Cardiology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Siswanto, B.B., Department of Cardiology and Vascular Medicine, Faculty of Medicine Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Virani, S.S., Michael E. DeBakey Veterans Affairs Medical Center & Baylor College of Medicine, Houston, TX, United States |
Background: Several comorbidities have been associated with an increased risk of severity and mortality in coronavirus disease 2019 (COVID-19), including hypertension, diabetes, cerebrovascular disease, chronic kidney disease, and chronic obstructive pulmonary disease. Purpose: In this systematic review and meta-analysis, we attempted to investigate the association between heart failure (HF) and poor outcome in patients with COVID-19. Methods: We performed a systematic literature search from PubMed, EuropePMC, SCOPUS, Cochrane Central Database, and medRxiv with the search terms, “Heart failure” and “COVID-19”. The outcome of interest was mortality and poor prognosis (defined by incidence of severe COVID-19 infection, admission to ICU, and use of ventilator) in patients with preexisting heart failure with coronavirus disease. Results: We identified 204 potential articles from our search, and 22 duplicates were removed. After screening of the titles and abstracts of the remaining 182 articles we identified 92 potentially relevant articles. We excluded 74 studies due to the following reasons: four studies were systematic reviews, two studies were meta-analyses, three articles were literature reviews, and 65 articles did not report on the outcome of interest. Finally, we included the remaining 18 studies in our qualitative synthesis and meta-analysis. There were 21,640 patients from 18 studies. HF was associated with hospitalization in COVID19 HR was 2.37 [1.48, 3.79; p < 0.001], high heterogeneity [I2, 82%; p < 0.001]. HF was associated with a poor outcome demonstrated by an OR of 2.86 [2.07; 3.95; p < 0.001] high heterogeneity [I2, 80%; p < 0.001]. Patient with preexisting HF was associated with higher mortality OR of 3.46 [2.52, 4.75; p < 0.001] moderately high heterogeneity [I2, 77%; p < 0.001]. Conclusion: Patients with heart failure are at increased risk for hospitalization, poor outcome, and death from COVID-19. A significant difference in mortality between patients with and without heart failure was observed, patients with heart failure having a higher mortality. © 2020 Elsevier Inc. |
Coronavirus disease 2019; Heart failure; Poor outcomes |
apnea hypopnea index; Article; artificial ventilation; coronavirus disease 2019; heart failure; hospitalization; human; incidence; meta analysis; mortality; outcome assessment; prevalence; prognosis; questionnaire; risk factor; systematic review; comorbidity; global health; heart failure; pandemic; procedures; risk assessment; survival rate; Comorbidity; COVID-19; Global Health; Heart Failure; Humans; Pandemics; Risk Assessment; Risk Factors; SARS-CoV-2; Survival Rate |
W.B. Saunders |
07356757 |
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33071085 |
Article |
Q1 |
725 |
6828 |
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272 |
Rozaliyani A., Sedono R., Sjam R., Tugiran M., Adawiyah R., Setianingrum F., Jusuf A., Sungkar S., Hagen F., Meis J.F., Wahyuningsih R. |
57203065912;56660590500;23398458200;57218291154;57208658742;57203061705;57205710194;57016857300;8050973500;55941779900;6507268400; |
Molecular typing and antifungal susceptibility study of Aspergillus spp. In intensive care unit (ICU) patients in Indonesia |
2021 |
Journal of Infection in Developing Countries |
15 |
7 |
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1014 |
1020 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112486692&doi=10.3855%2fjidc.13135&partnerID=40&md5=1a4e201e605dd6b5e4f597b467372d29 |
Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Anesthesiology, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia/Persahabatan Hospital, Jakarta, Indonesia; Department of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital (CWZ), Nijmegen, Netherlands; Department of Medical Mycology, Westerdijk Fungal Biodiversity Institute, Utrecht, Netherlands; Centre of Expertise in Mycology, Radboudumc/CWZ, Nijmegen, Netherlands; Department of Parasitology, Faculty of Medicine, Universitas Kristen, Jakarta, Indonesia |
Rozaliyani, A., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Sedono, R., Department of Anesthesiology, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Sjam, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Tugiran, M., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Adawiyah, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Setianingrum, F., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Jusuf, A., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia/Persahabatan Hospital, Jakarta, Indonesia; Sungkar, S., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Hagen, F., Department of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital (CWZ), Nijmegen, Netherlands, Department of Medical Mycology, Westerdijk Fungal Biodiversity Institute, Utrecht, Netherlands; Meis, J.F., Department of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital (CWZ), Nijmegen, Netherlands, Centre of Expertise in Mycology, Radboudumc/CWZ, Nijmegen, Netherlands; Wahyuningsih, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Parasitology, Faculty of Medicine, Universitas Kristen, Jakarta, Indonesia |
Introduction: Aspergillus exhibits a wide variation of susceptibility against antifungals according to genetic and environmental factors. Identification to the species level is necessary for appropriate treatment. Our objective was to determine the Aspergillus species involved in invasive pulmonary aspergillosis (IPA) among ICU patients in Jakarta, Indonesia. Methodology: The incidence of IPA in ICU patients at six hospitals in Jakarta from October 2012 - January 2015 was investigated. It involved a collection of endotracheal aspirates (ETA), nasal swabs and environmental samples around the hospitals, phenotypic screening, molecular characterization, and antifungal susceptibility testing. Results: Of the 405 patients investigated, 31 patients (7.7%) were diagnosed with putative IPA, from whom 45 Aspergillus isolates were collected. Aspergillus isolates were identified from pulmonary secretions in 24 patients, from nasal swabs in 7 patients and from both pulmonary secretions and nasal swabs in 7 patients. The phenotypic method showed 33 isolates of Aspergillus flavus (73.4%), nine Aspergillus fumigatus (20%), two Aspergillus niger (4.4%), and one Aspergillus nidulans (2.2%) isolate. Molecular identification showed 27 isolates of A. flavus (60.0%), eight isolates of A. fumigatus (17.8%), two isolates of A. niger (4.4%) and one isolate of A. nidulans (2.2%), while seven isolates (15.6%) were cryptic species or mixed isolates. Conclusions: Susceptibility testing showed all isolates were susceptible to amphotericin B, azoles and micafungin. Aspergillus flavus was the main causative organism in IPA cases in Jakarta, followed by A. fumigatus. © 2021 Journal of Infection in Developing Countries. All rights reserved. |
Aspergillus; Molecular typing; Susceptibility |
amphotericin B; internal transcribed spacer; isavuconazole; itraconazole; micafungin; microsatellite DNA; posaconazole; pyrrole; voriconazole; antifungal agent; microsatellite DNA; antifungal susceptibility; Article; Aspergillus; Aspergillus flavus; Aspergillus nidulans; Aspergillus niger; Aspergillus tamarii; cohort analysis; controlled study; fungus identification; human; incidence; Indonesia; intensive care unit; invasive aspergillosis; major clinical study; minimum effective concentration; minimum inhibitory concentration; multicenter study; nonhuman; Penicillium citrinum; phenotype; prospective study; Aspergillus; classification; clinical trial; drug effect; environmental microbiology; genetics; Indonesia; invasive aspergillosis; isolation and purification; microbiology; nose mucosa; |
Journal of Infection in Developing Countries |
20366590 |
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34343127 |
Article |
Q3 |
322 |
14136 |
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274 |
Andrijono, Prasetyo H., Gunardi E.R., Purwoto G., Winarto H. |
57192895639;57267560300;57192910998;14720170400;54080645300; |
The role of thrombocytosis as a prognostic factor for epithelial ovarian cancer [Peran Trombositosis sebagai Faktor Prognostik pada Kanker Ovarium Jenis Epitelial] |
2021 |
Indonesian Journal of Obstetrics and Gynecology |
9 |
3 |
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153 |
156 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115438818&doi=10.32771%2finajog.v9i3.1275&partnerID=40&md5=154dc76298f51380a153d1c86748bdf7 |
Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Andrijono, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Prasetyo, H., Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Gunardi, E.R., Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Purwoto, G., Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Winarto, H., Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Objective: To determine whether thrombocytosis is a prognostic factor for epithelial ovarian cancer and its relationship with 3-year overall survival in epithelial ovarian cancer patients. Methods: This study is a retrospective cohort study using medical record of patients with epithelial ovarian cancer registered in cancer registry of Oncology Division in Obstetrics and Gynecology Department, Dr. Cipto Mangunkusumo National General Hospital from January 2014 - July 2016. Data were collected when subjects were first until diseases outcomes identified in 3 years. Result: Out of 220 subjects, 132 (60%) were patients with advanced stage epithelial ovarian cancer (stage II/III/IV). 94 (42.7%) subjects had thrombocytosis. Patients with advanced stage of disease had higher risk of having thrombocytosis than the ones with earlier stage (p=0.005; OR=2.329). Correlation between thrombocytosis and 3-year overall survival was known to be insignificant (p=0.555). There was shorter mean time survival between patients with thrombocytosis and the ones without but the there was no significant difference in hazard ratio between the two groups (p = 0.399). Conclusions: Thrombocytosis is not a prognostic factor in patients with epithelial ovarian cancer. There is also no significant difference of 3-year overall survival between patients with or without thrombocytosis. © 2021 Indonesian Journal of Obstetrics and Gynecology. All rights reserved. |
Epithelial ovarian carcinoma; Prognosis; Thrombocytosis |
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Indonesian Society of Obstetrics and Gynecology |
23386401 |
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Article |
#N/A |
#N/A |
#N/A |
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275 |
Ocviyanti D., Sari J.M., Meutia Y. |
57189661230;57192922757;57268400900; |
Analysis of antenatal care quality in cases of referred pregnant women in emergency rooms based on MCH book records [Analisis Kualitas Asuhan Antenatal Berbasis Telaah Buku KIA pada Kasus Rujukan Ibu Hamil di Unit Gawat Darurat] |
2021 |
Indonesian Journal of Obstetrics and Gynecology |
9 |
3 |
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121 |
125 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115437292&doi=10.32771%2finajog.v9i3.1339&partnerID=40&md5=3f7ec96ae8c1dbf252ee97414e16bec7 |
Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Ocviyanti, D., Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Sari, J.M., Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Meutia, Y., Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Objective: To determine the quality of antenatal care received by pregnant women, and perceptions of pregnant women and antenatal care providers regarding antenatal care. Methods: A quantitative and qualitative study of cases of referred pregnant women in the Emergency Room (ER) of Dr. Cipto Mangunkusumo Hospital (RSCM) from 2017-2018 was conducted. Quantitative data was obtained by assessing the overall completeness of filling in the Maternal Child Health (MCH) book used to report the antenatal care received by the subjects. The completeness of antenatal care in the health facility was obtained using a checklist. Qualitative data was obtained by interviewing pregnant women and antenatal care providers in health facilities. Result: There were 1.442 cases of referred pregnant women in RSCM's ER for the year 2017-2018, of whom 820 possessed and could show their MCH Book. Pregnancy in adolescence below 20 years (9.1%) and pregnancy after age 35 (19.5%) were reported. Most pregnant women were well educated (74.3%), referred from hospital or clinic (57.6%), received antenatal care in a public health center (38.7%), were in labor (32%), and were in the third trimester of pregnancy (92%). All subjects presented an incomplete MCH book. Almost half had inadequate antenatal frequency (46%). The completeness of antenatal care components in health care was 90-100%. Qualitatively, the perceptions of mothers and antenatal care providers regarding quality of antenatal care, was inadequate. Conclusions: The quality of antenatal care in the case of referred pregnant women at the RSCM's ER based on MCH Book records did not meet the required standard. © Creative Commons Atribuição-Não Comercial 4.0 Internacional |
Antenatal care quality; MCH book |
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Indonesian Society of Obstetrics and Gynecology |
23386401 |
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Article |
#N/A |
#N/A |
#N/A |
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276 |
Situmorang H., Surya R., Hellyanti T. |
57195939562;56986345100;57217993236; |
Role of ambulatory laparoscopy in diagnosis of ascites with unknown etiology [Peran Laparoskopi dalam Mendiagnosis Asites akibat Etiologi yang tidak Diketahui] |
2021 |
Indonesian Journal of Obstetrics and Gynecology |
9 |
3 |
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162 |
168 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115358024&doi=10.32771%2finajog.v9i3.1362&partnerID=40&md5=5d4551247278e44c4fa03e7e3b9b12a3 |
Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo General Hospital Jakarta, Indonesia; Department of Pathology Anatomy, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Situmorang, H., Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo General Hospital Jakarta, Indonesia; Surya, R., Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo General Hospital Jakarta, Indonesia; Hellyanti, T., Department of Pathology Anatomy, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Objective: To determine the evidence about timing and role of laparoscopy in ascites work-up. Methods: : Case report Case: A-26-year-old P2 woman went to our hospital with a history of vaginal delivery 22 days before admission. She also presented with massive ascites. No obstetric complication was found. Transvaginal ultrasound revealed normal postpartum uterus and ovaries, surrounded with ascites. Both the liver and kidneys were found normal on ultrasound. Abdominal CT scan with contrast showed massive ascites with thickened omentum. Ascites ADA (adenosine deaminase) was 36 IU/L. Diagnostic laparoscopy was performed, we found massive yellowish ascites, miliary whitish lesions and hyperaemic tubal enlargement with thickening of the peritoneum. Biopsy was taken, pathology examination showed the appearance of chronic salpingitis and granulomatous peritonitis, in accordance with tuberculosis peritonitis. Conclusions: Laparoscopy should be the method of choice in diagnosing ascites with unknown etiology after inconclusive results of laboratory and radiological examination. Better visualization, typical appearance in peritoneal TB, chance to perform direct biopsy with lower risk of morbidity are the hallmarks of laparoscopy to be the method of choice to rule out the etiology of ascites. © 2021 Indonesian Journal of Obstetrics and Gynecology. All rights reserved. |
Ascites; Laparoscopy; Peritoneal tuberculosis |
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Indonesian Society of Obstetrics and Gynecology |
23386401 |
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Article |
#N/A |
#N/A |
#N/A |
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277 |
Sigit F.S., Trompet S., Tahapary D.L., Sartono E., Willems van Dijk K., Yazdanbakhsh M., Supali T., Smit J.W.A., Rosendaal F.R., de Mutsert R. |
57213595986;22954837300;55944492500;6701506022;57202571815;7006269286;6602742029;24577861400;7004174530;16042051400; |
The associations of leptin and adiponectin with the metabolic syndrome in an Indonesian and a Dutch population |
2021 |
Nutrition, Metabolism and Cardiovascular Diseases |
31 |
8 |
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2426 |
2435 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85108275064&doi=10.1016%2fj.numecd.2021.05.012&partnerID=40&md5=b98f561673afb80c486c693b20480984 |
Department of Clinical Epidemiology, Leiden University Medical Center, Albinusdreef 2, Leiden, 2333 ZA, Netherlands; Metabolic, Cardiovascular, and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine – Universitas Indonesia, Jalan Salemba Raya No 6, Jakarta, 10430, Indonesia; Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Albinusdreef 2, Leiden, 2333 ZA, Netherlands; Department of Internal Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine – Universitas Indonesia, Jalan Salemba Raya No 6, Jakarta, 10430, Indonesia; Department of Parasitology, Leiden University Medical Center, Albinusdreef 2, Leiden, 2333 ZA, Netherlands; Department of Human Genetics, Leiden University Medical Center, Albinusdreef 2, Leiden, 2333 ZA, Netherlands; Department of Internal Medicine, Section of Endocrinology, Leiden University Medical Center, Albinusdreef 2, Leiden, 2333 ZA, Netherlands; Department of Parasitology, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine – Universitas Indonesia, Jalan Salemba Raya No 6, Jakarta, 10430, Indonesia; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, Netherlands |
Sigit, F.S., Department of Clinical Epidemiology, Leiden University Medical Center, Albinusdreef 2, Leiden, 2333 ZA, Netherlands, Metabolic, Cardiovascular, and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine – Universitas Indonesia, Jalan Salemba Raya No 6, Jakarta, 10430, Indonesia; Trompet, S., Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Albinusdreef 2, Leiden, 2333 ZA, Netherlands; Tahapary, D.L., Metabolic, Cardiovascular, and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine – Universitas Indonesia, Jalan Salemba Raya No 6, Jakarta, 10430, Indonesia, Department of Internal Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine – Universitas Indonesia, Jalan Salemba Raya No 6, Jakarta, 10430, Indonesia; Sartono, E., Department of Parasitology, Leiden University Medical Center, Albinusdreef 2, Leiden, 2333 ZA, Netherlands; Willems van Dijk, K., Department of Human Genetics, Leiden University Medical Center, Albinusdreef 2, Leiden, 2333 ZA, Netherlands, Department of Internal Medicine, Section of Endocrinology, Leiden University Medical Center, Albinusdreef 2, Leiden, 2333 ZA, Netherlands; Yazdanbakhsh, M., Department of Parasitology, Leiden University Medical Center, Albinusdreef 2, Leiden, 2333 ZA, Netherlands; Supali, T., Department of Parasitology, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine – Universitas Indonesia, Jalan Salemba Raya No 6, Jakarta, 10430, Indonesia; Smit, J.W.A., Department of Internal Medicine, Section of Endocrinology, Leiden University Medical Center, Albinusdreef 2, Leiden, 2333 ZA, Netherlands, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, Netherlands; Rosendaal, F.R., Department of Clinical Epidemiology, Leiden University Medical Center, Albinusdreef 2, Leiden, 2333 ZA, Netherlands; de Mutsert, R., Department of Clinical Epidemiology, Leiden University Medical Center, Albinusdreef 2, Leiden, 2333 ZA, Netherlands |
Background and aims: At the same BMI, Asian populations develop cardiometabolic complications earlier than Western populations. We hypothesized that a different secretion of the adipocyte-derived hormones leptin and adiponectin plays a role and investigated the associations of the two hormones with the metabolic syndrome (MetS) in an Indonesian and a Dutch population. Methods and results: We performed cross-sectional analyses of the Netherlands Epidemiology of Obesity Study (n = 6602) and the SUGAR Scientific Programme Indonesia–Netherlands Study (n = 1461). We examined sex-stratified associations of leptin and adiponectin with MetS, using multivariate logistic regression including adjustment for total body fat. The mean (SD) leptin (mcg/L) were 4.7 (6.0) in Indonesian men, 18.6 (12.0) in Indonesian women, 9.1 (7.7) in Dutch men, and 23.4 (17.4) in Dutch women. The mean (SD) adiponectin (mg/L) were 5.7 (5.4), 7.5 (7.1), 6.6 (3.3), and 11.3 (4.9), respectively. Within the same BMI category, leptin concentrations were similar in the two populations, whereas adiponectin was lower in the Indonesian population. Per SD of leptin, adjusted prevalence odds ratios (ORs, 95%CI) of MetS were 0.9 (0.6–1.2) in Indonesian men, 1.1 (0.9–1.4) in Indonesian women, 2.2 (1.6–2.8) in Dutch men, and 1.2 (1.0–1.5) in Dutch women. Per SD of adiponectin, the ORs were 0.9 (0.7–1.2), 0.8 (0.7–1.0), 0.6 (0.6–0.8), and 0.4 (0.4–0.5), respectively. Conclusions: Despite lower adiponectin levels, adiponectin was not related to the MetS in the Indonesian population and can not explain their increased cardiometabolic risk at the same BMI. © 2021 The Author(s) |
Adiponectin; Asian; Leptin; The metabolic syndrome (MetS); Total body fat; Western |
adiponectin; ADIPOQ protein, human; biological marker; LEP protein, human; leptin; adolescent; adult; aged; blood; body mass; clinical trial; comparative study; cross-sectional study; female; human; Indonesia; male; metabolic syndrome X; middle aged; multicenter study; Netherlands; obesity; prevalence; randomized controlled trial (topic); risk assessment; sex factor; very elderly; young adult; Adiponectin; Adiposity; Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Body Mass Index; Cardiometabolic Risk Factors; Cross-Sectional Studies; Female; Humans; Indonesia; Leptin; Male; Metabolic Syndrome; Middle Aged; Netherlands; Prevalence; Randomized Controlled Trials as Topic; Risk Assessment; Sex Factors; Young Adult |
Elsevier B.V. |
09394753 |
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34154890 |
Article |
Q1 |
1127 |
3665 |
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279 |
Mesiano T., Kurniawan M., Saputri K.M., Hidayat R., Permana A.P., Rasyid A., Harris S. |
57204830976;57196001182;57226439255;57225289998;57218558566;56703146700;55325116600; |
Endovascular Treatment in Acute Ischemic Stroke Adoption and Practice: A Single-Center Indonesian Experience |
2021 |
Cerebrovascular Diseases Extra |
11 |
2 |
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72 |
76 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111589407&doi=10.1159%2f000517183&partnerID=40&md5=aa029d4460bd9e0c30ddd00eef1a7bfd |
Division of Neurovascular and Neurosonology, Department of Neurology, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Vascular, Department of Neurosurgery, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Mesiano, T., Division of Neurovascular and Neurosonology, Department of Neurology, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Kurniawan, M., Division of Neurovascular and Neurosonology, Department of Neurology, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Saputri, K.M., Division of Neurovascular and Neurosonology, Department of Neurology, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Hidayat, R., Division of Neurovascular and Neurosonology, Department of Neurology, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Permana, A.P., Division of Vascular, Department of Neurosurgery, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rasyid, A., Division of Neurovascular and Neurosonology, Department of Neurology, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Harris, S., Division of Neurovascular and Neurosonology, Department of Neurology, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Indonesia is facing increasing stroke prevalence in the past 5 years. Ischemic stroke imposes economic and productivity burden if it is not addressed properly. Endovascular treatment studies are conducted in developed countries where facilities and cost do not count in therapy consideration if it is indicated. Developing countries like Indonesia should work hard to provide the best hyperacute stroke care with protocol deviation and limitation. This is the first review on endovascular treatment practice in a top single-center hospital in Indonesia. Further improvement is needed to catch up with state-of-the-art hyperacute ischemic stroke treatment. © 2021 |
Acute ischemic stroke; Developing countries; Endovascular treatment; Indonesia; Intravenous thrombolysis |
alteplase; glucose; fibrinolytic agent; acute ischemic stroke; adult; aged; Article; clinical article; clinical practice; controlled study; coronary artery disease; disease burden; endovascular surgery; female; glucose blood level; health care; heart failure; human; Indonesian; internal carotid artery; male; mechanical thrombectomy; middle cerebral artery; National Institutes of Health Stroke Scale; personal experience; recanalization; smoking; adverse event; brain ischemia; developing country; fibrinolytic therapy; Indonesia; intravenous drug administration; middle aged; prevalence; retrospective study; thrombectomy; time factor; treatment outcome; very elderly; Adult; Aged; Aged, 80 and over; Developing Countries; Endovascular Procedures; Female; Fibrinolytic Agents; Humans; Indonesia; I |
S. Karger AG |
16645456 |
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34284377 |
Article |
Q1 |
1015 |
4300 |
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284 |
Rustamadji P., Takbir M., Wuyung P.E., Kusmardi K., Wiyarta E. |
55321572200;57318063000;57192889605;56966625300;57221521342; |
Correlation between CD 34 and CD 68 expression in placental malaria with maternal anemia |
2021 |
Tropical Parasitology |
11 |
2 |
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92 |
96 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118308075&doi=10.4103%2ftp.TP_108_20&partnerID=40&md5=a57c3187c0926ddc2e00415c87f7f7bb |
Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Anatomical Pathology, Labuha Hospital, North Maluku, South Halmahera, Indonesia |
Rustamadji, P., Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Takbir, M., Department of Anatomical Pathology, Labuha Hospital, North Maluku, South Halmahera, Indonesia; Wuyung, P.E., Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Kusmardi, K., Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Wiyarta, E., Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Background: Malaria is the second most life-threatening infectious disease in Indonesia, causing approximately 1-3 million deaths annually. Histopathologic studies assessing CD 68 and CD 34 protein expression in placental malaria and its association with maternal anemia are essential to determine the prognosis of malaria in pregnancy. Materials and Methods: This cross-sectional study was carried out in 2017. Thirty biopsy samples of human placental tissue were obtained from Timika and Sumba, and ten normal biopsy samples were taken from the Pathological Anatomy Department of Cipto Mangunkusumo General Hospital as comparisons. CD 34 and CD 68 protein expressions were determined using immunohistochemistry, and the resulting data were analyzed using SPSS. Results: Average hemoglobin (Hb) level was 9.5 mg/dL, 11.5 mg/dL, and 9.9 mg/dL in acute infection, chronic infection, and latent infection, respectively. A positive correlation was found between CD 68 protein expression and maternal Hb level. No correlation was found between CD34 expression and maternal anemia. Conclusions: CD 68 expression in placental tissue biopsy from Timika and Sumba residents with placental malaria was shown to be positively correlated with maternal anemia. Immunohistochemical examination of CD 68 may play a role in the early diagnosis of malaria. © 2021 Tropical Parasitology | Published by Wolters Kluwer - Medknow. |
CD 34; CD 68; Maternal anemia; Placental malaria |
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Wolters Kluwer Medknow Publications |
22295070 |
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Article |
Q3 |
418 |
11707 |
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285 |
MANSYUR A.S., WIDYAHENING I.S., SUDARSONO N.C. |
57312107800;54893154400;57201862518; |
Incidence of musculoskeletal injuries among Indonesian volleyball athletes during a national training and championship |
2021 |
Gazzetta Medica Italiana Archivio per le Scienze Mediche |
180 |
7-8 |
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374 |
379 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117904317&doi=10.23736%2fS0393-3660.20.04382-X&partnerID=40&md5=706fa0522bf3dbc8cae2b23a407d416b |
Sports Medicine Study Program, Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Division of Family Medicine, Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Division of Sports Medicine, Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
MANSYUR, A.S., Sports Medicine Study Program, Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; WIDYAHENING, I.S., Division of Family Medicine, Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; SUDARSONO, N.C., Division of Sports Medicine, Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
BACKGROUND: This study aimed to find out the incidence and characteristics of musculoskeletal injuries among Indonesian volleyball athletes during a national volleyball training and championship. METHODS: A prospective cohort study involving 34 Indonesian volleyball national team athletes (18 male and 16 female) during one volleyball national training and championship in July-September 2019 was conducted. All athletes were observed for 11 weeks and the incidence and the characteristics (duration, pain level, severity in loss time, nature, recurrence, anatomical location and types) of the injuries were documented. Some etiological factors of the injuries such as the court zone (back, front/net, and un-specified) time of injury (practice, competition or both), injury mechanism (ball contact, player contact, surface contact, non-contact or overuse), biomechanics (bending, compression, repetitive or traction) and movements (blocking, digging, passing, serving, spiking, or not specific) were also recorded. Incidence of injuries was presented in 1000 player hours. RESULTS: The incidence of injuries was 20.4/1000 player hours. Only one out of the 34 athletes did not have injury. Injuries occurred most frequently in the knee (36%), followed by the ankle (18%) and waist (16%). The most common type of injuries was sprain (21%) and tendinitis (21%) followed by low back pain (13%). The overuse and recurrence type of injuries were much more dominant to the acute one. CONCLUSIONS: Musculoskeletal injuries were common among Indonesian volleyball athletes. This adds information to the limited available evidence concerning the incidence, prevalence and etiology of volleyball-specific injuries which were needed to prevent its occurrence. © 2021 Edizioni Minerva Medica. All rights reserved. |
Athletes; Cumulative trauma disorders; Sports medicine; Volleyball |
adult; ankle; Article; athlete; beep test; biomechanics; body mass; bursitis; cardiopulmonary endurance; clinical article; cohort analysis; compression; concussion; court; elbow; female; hand-grip strength test; head; human; incidence; Indonesian; knee; low back pain; male; maximal oxygen uptake; muscle exercise; muscle strength; musculoskeletal injury; nuclear magnetic resonance imaging; patellofemoral pain syndrome; physical examination; prospective study; shoulder; shuttle run test; situp test; sprain; tendinitis; training; volleyball; x-ray computed tomography |
Edizioni Minerva Medica |
03933660 |
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Article |
Q4 |
114 |
27889 |
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286 |
Wijaya I.P. |
57193731572; |
The Importance of Selecting Permanent Pacemaker, Evaluating the Heart and Assessing Quality of Life in Cardiac Patient |
2021 |
Acta medica Indonesiana |
53 |
3 |
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243 |
244 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117859074&partnerID=40&md5=9e57130d3901679cfdd2331bb124a29a |
Division of Cardiology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo HospitalJakarta, Indonesia |
Wijaya, I.P., Division of Cardiology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo HospitalJakarta, Indonesia |
The use of pacemakers is necessary for patients with symptomatic bradycardia. Pacemaker implantation also acts as a life-saving procedure. However, there are several reports that patients with a pacemaker (the most widely used pacemaker is on the right ventricle, known as single chamber pacemaker) had disturbances in left ventricle contraction lead to left ventricular systolic dysfunction. Global Longitudinal Strain (GLS) Echocardiography can confirm these left ventricular disturbances. Echocardiography examination is best carried out before and after single-chamber PPM implantation. This study compares PPM placement in apical Right Ventricle (RV) and Right Ventricular Outflow Tract (RVOT) and compares paced QRS duration 150 ms and > 150 ms. Pacing burden >40% causes subclinical left ventricular systolic dysfunction after a month of PPM implantation with decreased GLS in apical RV pacing.This study gives additional information that PPM placement is preferably in RVOT with some specific settings. However, there are many ways to reduce the effects of impaired left ventricular function due to lead installation on the PPM single-chamber device. By using the PPM device which has a dual chamber, the leads will be placed in RVOT and also in the right atrium with atrial-ventricle synchronization. The aim is to avoid impaired left ventricular pump function as supported by a systematic review which states the superiority of dual-chamber PPM over single-chamber PPM in reducing atrial fibrillation and pacemaker syndrome. In the importance of quality of life related to heart disease, the Indonesian version of the MacNew questionnaire can be used. This questionnaire seeks the quality of life of patients with coronary heart disease after revascularization surgery and has undergone rehabilitation. Another important thing is the suitability of the adaptation to the original English version. |
cardiac patient; global longitudinal strain; MacNew questionnaire; pacemaker |
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NLM (Medline) |
01259326 |
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34611061 |
Article |
Q3 |
321 |
14162 |
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