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769 |
Birowo P., Tendi W., Rasyid N., Turek P.J., Sini I.R., Rizal M. |
6504153311;57208641745;56245069300;7006101528;56013404300;57225198196; |
Successful targeted testicular sperm extraction using microsurgical technique (microtese) following fine needle aspiration (FNA) mapping in a non-obstructive azoospermia (NOA) patient: A case report |
2021 |
Journal of Reproduction and Infertility |
22 |
1 |
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65 |
69 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109425367&doi=10.18502%2fjri.v22i1.4997&partnerID=40&md5=fa081e0db7b5deb36d248beb2dcda6dd |
Department of Urology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Indonesian Reproductive Science Institute, Bunda General Hospital, Jakarta, Indonesia; Turek Clinic, San Francisco, United States |
Birowo, P., Department of Urology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Indonesian Reproductive Science Institute, Bunda General Hospital, Jakarta, Indonesia; Tendi, W., Department of Urology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Indonesian Reproductive Science Institute, Bunda General Hospital, Jakarta, Indonesia; Rasyid, N., Department of Urology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Turek, P.J., Turek Clinic, San Francisco, United States; Sini, I.R., Indonesian Reproductive Science Institute, Bunda General Hospital, Jakarta, Indonesia; Rizal, M., Indonesian Reproductive Science Institute, Bunda General Hospital, Jakarta, Indonesia |
Background: Management for male infertility can be difficult for some cases. Surgical intervention has long been thought as the last resort to help married couples to conceive. The current guideline recommends testicular sperm extraction with microsurgery technique (microTESE) in severe cases of male infertility. However, the success rate still varies. Thus, a new strategy was needed to further increase the sperm retrieval success rate. Case Presentation: A 39-year-old male with a history of failed sperm extraction, non-obstructive azoospermia (NOA) and Y-chromosomal microdeletion came to the fertility center to undergo sperm retrieval. Fine needle aspiration (FNA) Mapping was performed prior to microTESE to increase the accuracy of sperm retrieval. After further examination with laser assisted immotile sperm selection (LAISS), five spermatozoa were found. Conclusion: The combination of FNA Mapping and microTESE increases the chance of a successful sperm extraction. © 2021 Avicenna Research Institute. All rights reserved. |
Fna mapping; Laiss; Microtese; Noa; Y-chromosomal microdeletion |
chorionic gonadotropin; clomifene citrate; follitropin; ovutrig; testosterone; adult; Article; azoospermia; case report; chromosome deletion; clinical article; clinical effectiveness; echography; fine needle aspiration biopsy; fine needle aspiration mapping; human; human tissue; intracytoplasmic sperm injection; laser assisted immotile sperm selection; male; male infertility; microsurgical epididymal sperm aspiration; microsurgical testicular sperm extraction; percutaneous epididymal sperm aspiration; physical examination; pronucleus; sperm retrieval; spermatid; spermatocyte; spermatozoon; testicular sperm extraction; testis biopsy; testis size; varicocele; Y chromosome |
Avicenna Research Institute |
22285482 |
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Article |
Q3 |
495 |
10168 |
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770 |
Saroyo Y.B., Wibowo N., Irwinda R., Prijanti A.R., Yunihastuti E., Bardosono S., Krisnadi S.R., Permata P.I., Wijaya S., Santawi V.P.A. |
57164888400;15049026900;57190855256;57190863386;57221273925;21933841000;56660648900;57225151181;56685332700;57192917419; |
Oxidative Stress Induced Damage and Early Senescence in Preterm Placenta |
2021 |
Journal of Pregnancy |
2021 |
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9923761 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109338598&doi=10.1155%2f2021%2f9923761&partnerID=40&md5=f6580c90345ba249ad3c787766d49062 |
Maternal Fetal Division, Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia/Cipto-Mangunkusumo Hospital, Indonesia; Department of Biochemistry and Molecular Biology, Faculty of Medicine Universitas Indonesia/Cipto-Mangunkusumo Hospital, Indonesia; Division of Allergy Immunology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia/Cipto-Mangunkusumo Hospital, Indonesia; Department of Clinical Nutrition, Universitas Indonesia/Cipto-Mangunkusumo Hospital, Indonesia; Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital, Indonesia; Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Indonesia |
Saroyo, Y.B., Maternal Fetal Division, Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia/Cipto-Mangunkusumo Hospital, Indonesia; Wibowo, N., Maternal Fetal Division, Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia/Cipto-Mangunkusumo Hospital, Indonesia; Irwinda, R., Maternal Fetal Division, Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia/Cipto-Mangunkusumo Hospital, Indonesia; Prijanti, A.R., Department of Biochemistry and Molecular Biology, Faculty of Medicine Universitas Indonesia/Cipto-Mangunkusumo Hospital, Indonesia; Yunihastuti, E., Division of Allergy Immunology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia/Cipto-Mangunkusumo Hospital, Indonesia; Bardosono, S., Department of Clinical Nutrition, Universitas Indonesia/Cipto-Mangunkusumo Hospital, Indonesia; Krisnadi, S.R., Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital, Indonesia; Permata, P.I., Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Indonesia; Wijaya, S., Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Indonesia; Santawi, V.P.A., Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Indonesia |
Introduction. Senescent cells have been demonstrated to release High Mobility Group Box 1 (HMGB1) which induces labor through an inflammatory pathway. This research is aimed at demonstrating whether telomere shortening, proinflammatory HMGB1, and oxidative damage marker 8-OHdG play a role in the placenta of preterm birth in comparison to term birth. Method. A cross-sectional study on 67 full thickness of the placenta obtained from mothers with term and preterm birth. Mothers with clinical signs of infection (fever>38°C, leukocytosis>18000/μL, or abnormal vaginal discharge) and other pregnancy complications were excluded. Real-time polymerase chain reaction was performed to measure T/S ratio and ELISA quantification to measure the amount of HMGB1 and 8-OHdG. Result. A total of 34 placentas from preterm and 33 placentas from term birth were examined. Maternal characteristics were comparable between the two groups. There were no statistical difference of T/S ratio (p=0.181), HMGB1 (p=0.119), and 8-OHdG (p=0.144) between the preterm and term groups. HMGB1 was moderately correlated with 8-OHdG (r=0.314). Telomere T/S ratio of the placenta did not differ between preterm and term labor despite difference in gestational age, suggesting earlier shortening in the preterm group. It is possible that critical telomere length has been achieved in both term and preterm placenta that warrants labor through senescence process. The result of our study also showed that HMGB1 was not correlated to telomere length, due to the fact that HMGB1 is not upregulated until the critical length of telomere for senescence is exhibited. Conclusion. Similar telomere length might be exhibited due to early telomere shortening in preterm birth that mimics the term placenta. The relationship between placental telomere shortening and HMGB1 release remains to be uncovered. Further research is needed to discover the factors leading to early telomere shortening in the placenta of preterm birth. © 2021 Yudianto Budi Saroyo et al. |
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cross-sectional study; female; human; metabolism; newborn; oxidative stress; placenta; pregnancy; prematurity; telomere shortening; Cross-Sectional Studies; Female; Humans; Infant, Newborn; Oxidative Stress; Placenta; Pregnancy; Premature Birth; Telomere Shortening |
Hindawi Limited |
20902727 |
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34258068 |
Article |
Q2 |
828 |
5768 |
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773 |
Rahman Y., Krisanti R.I.A., Wisnu W., Sitohang I.B.S. |
57225022226;57210797305;57200425452;56734569200; |
The comparison between free thyroxine and thyroid-stimulating hormone levels on melasma severity: A cross-sectional study |
2021 |
Open Access Macedonian Journal of Medical Sciences |
9 |
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426 |
431 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85108964003&doi=10.3889%2foamjms.2021.5952&partnerID=40&md5=b495093253a6b484fb6b524298865e4d |
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Salemba, Jakarta, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Salemba, Jakarta, Indonesia |
Rahman, Y., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Salemba, Jakarta, Indonesia; Krisanti, R.I.A., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Salemba, Jakarta, Indonesia; Wisnu, W., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Salemba, Jakarta, Indonesia; Sitohang, I.B.S., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Salemba, Jakarta, Indonesia |
BACKGROUND: Melasma has been suspected to be linked with levels of thyroid hormone. There is no study that explains the association between thyroid hormone levels with melasma severity. AIM: This study aims to find the discrepancies in the levels of thyroid hormone in varying severity of melasma using two different measurement techniques. METHODS: Subjects were chosen consecutively from the dermatology clinic at RSUPN Dr. Cipto Mangunkusumo hospital. Forty-eight patients participated in this study were categorized into mild melasma and moderate-severe melasma based on modified melasma area and severity index (mMASI) and Janus II measurement. RESULTS: Statistically, mMASI measurement showed no significant association between varying melasma severity with levels of thyroid stimulating hormone and free T4 (FT4), p = 0.375 and p = 0.208, respectively. The Janus II examination using polarized light modality has a weak positive correlation with the serum FT4 level (r = 0.3; p = 0.039). Weak correlation was also found between the two measurement strategies, Janus II and mMASI (r = 0.314; p = 0.03). CONCLUSION: There are no significant differences observed in levels of thyroid hormone between subjects with varying degrees of melasma severity. © 2021 Yusnita Rahman, Roro Inge Ade Krisanti, Wismandari Wisnu, Irma Bernadette S. Sitohang. |
Free T4; Janus II facial analysis system; Melasma; Modified melasma area and severity index; Thyroid-stimulating hormone |
thyrotropin; adult; Article; chloasma; clinical article; cross-sectional study; disease severity; female; free thyroxine index; human; male |
Scientific Foundation SPIROSKI |
18579655 |
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Article |
Q3 |
288 |
15252 |
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779 |
Kartika R.W., Alwi I., Suyatna F.D., Yunir E., Waspadji S., Immanuel S., Silalahi T., Sungkar S., Rachmat J., Bardosono S., Reksodiputro M.H. |
57223447932;15055173800;56039633100;36520254800;8678136400;12777341300;56275255400;57016857300;6507225348;21933841000;35090488800; |
Advance-Platelet Rich Fibrin and Hyaluronic Acid Combination Improves Interleukin-6 and Granulation Index in Diabetic Foot Ulcer Patients |
2021 |
Indonesian Biomedical Journal |
13 |
2 |
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170 |
177 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85108646812&doi=10.18585%2finabj.v13i2.1501&partnerID=40&md5=38a4d6d4cd5994b04badcabc1939a76e |
Doctoral Program in Medical Science, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, Indonesia; Department of Thoracic, Cardiac and Vascular Surgery, Krida Wacana Christian University, Jl. Arjuna Utara No.6, Jakarta, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo General Hospital, Jl. Salemba Raya No.6, Jakarta, Indonesia; Department of Clinical Pharmacology, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, Indonesia; Department of Clinical Pathology, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo General Hospital, Jl. Salemba Raya No.6, Jakarta, Indonesia; Department of Internal Medicine, Krida Wacana Christian University, Jl. Arjuna Utara No.6, Jakarta, Indonesia; Department of Clinical Parasitology, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, Indonesia; Department of Thoracic Cardiac and Vascular Surgery, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, Indonesia; Department of Nutrition, Faculty of Medicine Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, Indonesia; Facial Plastic Reconstructive Division, Department of Otorhinolaryngology, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo General Hospital, Jl. Salemba Raya No.6, Jakarta, Indonesia |
Kartika, R.W., Doctoral Program in Medical Science, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, Indonesia, Department of Thoracic, Cardiac and Vascular Surgery, Krida Wacana Christian University, Jl. Arjuna Utara No.6, Jakarta, Indonesia; Alwi, I., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo General Hospital, Jl. Salemba Raya No.6, Jakarta, Indonesia; Suyatna, F.D., Department of Clinical Pharmacology, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, Indonesia; Yunir, E., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo General Hospital, Jl. Salemba Raya No.6, Jakarta, Indonesia; Waspadji, S., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo General Hospital, Jl. Salemba Raya No.6, Jakarta, Indonesia; Immanuel, S., Department of Clinical Pathology, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo General Hospital, Jl. Salemba Raya No.6, Jakarta, Indonesia; Silalahi, T., Department of Internal Medicine, Krida Wacana Christian University, Jl. Arjuna Utara No.6, Jakarta, Indonesia; Sungkar, S., Department of Clinical Parasitology, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, Indonesia; Rachmat, J., Department of Thoracic Cardiac and Vascular Surgery, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, Indonesia; Bardosono, S., Department of Nutrition, Faculty of Medicine Universitas Indonesia, Jl. Salemba Raya No.6, Jakarta, Indonesia; Reksodiputro, M.H., Facial Plastic Reconstructive Division, Department of Otorhinolaryngology, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo General Hospital, Jl. Salemba Raya No.6, Jakarta, Indonesia |
BACKGROUND: Diabetic foot ulcer (DFU) is the most common and threatening complication of Diabetes Mellitus (DM). Ideal wound dressing for DFU management should relieve symptoms, provide wound protection, and encourage healing. Advanced-Platelet Rich Fibrin (A-PRF) and Hyaluronic Acid (HA) have been proven to improve wound healing process. This study was aimed to demonstrate the ability of combination of A-PRF and HA in reducing inflammation and improving DFU tissue healing. METHODS: Twenty DFU subjects were involved in this study, and divided into two groups based on the topical fibrin gel treatment: A-PRF + HA group and A-PRF only group. A-PRF was obtained by peripheral blood centrifugation. A-PRF + HA was prepared by homogening A-PRF and AH with a ratio of 1:0.6. Interleukin-6 (IL-6) level, granulation index (GI), numeric pain score (NPS), and inflammation clinical symptoms (ICS) were assessed on day-0, 3, 7 and 14. RESULTS: Wound swabs' IL-6 level on day-7 was found to be significantly lower in A-PRF + HA compared to A-PRF alone (p=0.041). The IL-6 level reduction also found to be significant higher either in wound swabs (day 0-7, p=0.015) or fibrin gel (day 0-3, p=0.049; day 0-7, p=0.034). A-PRF + HA treatment significantly increased the GI even since day-3 (p=0.043), with lower NPS (p<0.001), and ICS score. CONCLUSION: The combination of A-PRF and HA increases the GI in DFU healing by reducing the inflammation state which will induce the angiogenesis process, as well as reducing pain in DFU subjects better than A-PRF alone. © 2021. All Rights Reserved. |
angiogenesis; inflammation; interleukin-6; proliferation; wound healing |
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Prodia Education and Research Institute |
20853297 |
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Article |
Q4 |
160 |
22228 |
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782 |
Palupi-Baroto R., Hermawan K., Murni I.K., Nurlitasari T., Prihastuti Y., Sekali D.R.K., Ambarsari C.G. |
56495463300;57224908584;55734483200;57224895124;57224909176;57224897130;57211850895; |
High fibroblast growth factor 23 as a biomarker for severe cardiac impairment in children with chronic kidney disease: A single tertiary center study |
2021 |
International Journal of Nephrology and Renovascular Disease |
14 |
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165 |
171 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85108541273&doi=10.2147%2fIJNRD.S304143&partnerID=40&md5=ba9cd0eab6e18711499e83b6c4812aa7 |
Department of Child Health, Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta, Indonesia; Department of Child Health, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Palupi-Baroto, R., Department of Child Health, Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta, Indonesia; Hermawan, K., Department of Child Health, Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta, Indonesia; Murni, I.K., Department of Child Health, Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta, Indonesia; Nurlitasari, T., Department of Child Health, Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta, Indonesia; Prihastuti, Y., Department of Child Health, Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta, Indonesia; Sekali, D.R.K., Department of Child Health, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Ambarsari, C.G., Department of Child Health, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Introduction: Left ventricular hypertrophy (LVH) is the most common cardiac abnormality in chronic kidney disease (CKD). Changes in cardiac geometry and functions may occur in an early stage and worsen as CKD progresses. Recently, the role of fibroblast growth factor 23 (FGF23) is being highlighted and investigated in CKD-related cardiomyopathy. However, only a few studies have reviewed the utilization of FGF23 as a diagnostic biomarker in the pediatric CKD population. Purpose: This study aimed to identify the role of FGF23 as a biomarker in assessing cardiac changes in children with CKD. Patients and Methods: We conducted a cross-sectional study that involved children aged 2 to 18 years old with CKD stages 2 to 5D in Dr. Sardjito General Hospital, Yogyakarta, Indonesia. The level of FGF23 was measured using an immunometric enzyme-linked immunosorbent assay. LVMI, RWT, and left ventricular ejection fraction (LVEF) were assessed with echocardiography. Receiver-operating characteristic (ROC) analyses were conducted to assess the diagnostic performance of FGF23 in detecting LVH with impaired contractility. Results: A total of 43 children with CKD stages 2 to 5D were included, among whom the prevalence of LVH diagnosis was 95.35%. The area under the curve (AUC) of FGF23 to assess LVH and systolic dysfunction was 0.82 (95% CI 0.62–1.0), and the optimal cutoff point was 1413 RU/mL (sensitivity 80%, specificity 78.95%). The median concentration of FGF23 increased with the decreasing eGFR and the increasing LVMI although the systolic and diastolic functions were preserved. Conclusion: FGF23 might be used as an early biomarker to detect cardiac changes in pediatric CKD patients, particularly for LVH and impaired systolic function among children with CKD stage 2 and higher. © 2021 Palupi-Baroto et al. |
Dialysis; End-stage kidney disease; FGF23; Left ventricular hypertrophy; Ventricular ejection fraction |
biological marker; fibroblast growth factor 23; adolescent; adult; anemia; area under the curve; Article; child; chronic kidney failure; clinical article; cross-sectional study; diabetic nephropathy; diagnostic test accuracy study; diagnostic value; disease severity; echocardiography; enzyme linked immunosorbent assay; estimated glomerular filtration rate; female; glomerulonephritis; heart left ventricle contractility; heart left ventricle contraction; heart left ventricle ejection fraction; heart left ventricle filling; heart left ventricle mass; heart ventricle hypertrophy; human; hypertension; Indonesia; kidney agenesis; kidney calcification; kidney dysplasia; kidney hypoplasia; lupus erythematosus nephritis; male; nephrotic syndrome; obstructive uropathy; preschool child; prevalence; r |
Dove Medical Press Ltd |
11787058 |
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Article |
Q2 |
846 |
5589 |
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783 |
Prabowo K.A., Ellenzy G., Wijaya M.C., Kloping Y.P. |
57224859187;57224861188;57221739074;57205266766; |
Impact of Work from Home Policy during the COVID-19 Pandemic on Mental Health and Reproductive Health of Women in Indonesia |
2021 |
International Journal of Sexual Health |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85108422054&doi=10.1080%2f19317611.2021.1928808&partnerID=40&md5=0d311414603955c5b93af73ca9ec0c60 |
Faculty of Medicine, Airlangga University, Surabaya, Indonesia; Department of Psychiatry, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia |
Prabowo, K.A., Faculty of Medicine, Airlangga University, Surabaya, Indonesia; Ellenzy, G., Department of Psychiatry, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Wijaya, M.C., Faculty of Medicine, Airlangga University, Surabaya, Indonesia; Kloping, Y.P., Faculty of Medicine, Airlangga University, Surabaya, Indonesia |
Objectives: This study aimed to assess the impact of work from home (WFH) during the COVID-19 pandemic on the mental health and reproductive health of women in Indonesia. To the best of our knowledge, this is the first study evaluating the impact of WFH policy on said health aspects in Indonesia. Methods: We conducted an observational study with a cross-sectional approach using an online survey among premenopausal married women in Indonesia. The survey included the General Health Questionnaire (GHQ-12) for psychological distress, average sexual intercourse frequency (SIF) per week, contraception use, change of menstrual pattern, and desire for having children. To analyze the effect of WFH, the participants were divided into groups based on their WFH compliance: (1) Both couples (her and her spouse) work from home, (2) Only the wife works from home, (3) Only the husband works from home, and (4) Neither works from home. Results: 348 women were included in this study. Psychological distress occurred in 48.0% (n = 167) participants. No significant difference was found between the WFH groups (χ 2[3, N = 348] = 2.077, p =.56)). The average weekly SIF was found to be significantly fewer during WFH (T = 5014, z = −5.598, p <.001). However, only 22.7% (n = 79) participants reported the use of contraception and 52.9% (n = 196) participants still wanted to have children. Change of menstrual pattern occurred in 31.6% (n = 110) participants and were significantly correlated to psychological distress (rs =.126, p =.018). Conclusions: WFH does not aggravate the effect of the pandemic on women's mental and reproductive health in Indonesia. A significant number of them still desire to have children and contraceptive prevalence is low. © 2021 Taylor & Francis Group, LLC. |
COVID-19; mental health; pandemic; Quarantine; reproductive health |
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Routledge |
19317611 |
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Article |
Q1 |
809 |
5958 |
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784 |
Bustamam A., Sarwinda D., Paradisa R.H., Victor A.A., Yudantha A.R., Siswantining T. |
36815737800;56119401500;57221562575;57191055282;55489644900;57193446800; |
Evaluation of convolutional neural network variants for diagnosis of diabetic retinopathy |
2021 |
Communications in Mathematical Biology and Neuroscience |
2021 |
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42 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85108354325&doi=10.28919%2fcmbn%2f5660&partnerID=40&md5=46f614ba3ad44a65354d6ec3e2b41ab1 |
Department of Mathematics, Faculty of Mathematics and Natural Science, Universitas Indonesia, Depok, Indonesia; Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia |
Bustamam, A., Department of Mathematics, Faculty of Mathematics and Natural Science, Universitas Indonesia, Depok, Indonesia; Sarwinda, D., Department of Mathematics, Faculty of Mathematics and Natural Science, Universitas Indonesia, Depok, Indonesia; Paradisa, R.H., Department of Mathematics, Faculty of Mathematics and Natural Science, Universitas Indonesia, Depok, Indonesia; Victor, A.A., Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Yudantha, A.R., Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Siswantining, T., Department of Mathematics, Faculty of Mathematics and Natural Science, Universitas Indonesia, Depok, Indonesia |
Diabetic Retinopathy (DR) is a long-term complication of Diabetes Mellitus (DM) that impairs vision. This stage occurs in visual impairment and blindness if treated late. DR identified through scanning fundus images. A technique on classifying DR in fundus images is the deep learning approach, one of the methods of implementing machine learning. In this study, the Convolutional Neural Networks (CNN) method applied with the ResNet-50 and DenseNet-121 architectures. The data adopted in this analysis was generated from DIARETDB1, an online database containing fundus images. Then, the pre-processing stage is carried out on the fundus image to improve model performance, such as selected the green channel from the images and inverted it, converted the images into grayscale images, and applied Contrast Limited Adaptive Histogram Equalization (CLAHE) for uniform contrast in the images. The outcome of this research indicates that the ResNet-50 model is better than DenseNet-121 in detecting DR. The most reliable results from the ResNet-50 model's case testing are accuracy, precision, and recall of 95%, 98%, and 96% respectively. © 2021, SCIK Publishing Corporation. All rights reserved. |
Deep learning; Densenet; Diabetic retinopathy; Fundus image; Resnet |
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SCIK Publishing Corporation |
20522541 |
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Article |
Q4 |
189 |
20081 |
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797 |
Putri N.M., Tunjung N., Sadikin P.M. |
57192904294;57208446370;56527444500; |
Closure of meningomyelocele defects using various types of keystone-design perforator island flaps |
2021 |
Archives of Plastic Surgery |
48 |
3 |
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261 |
268 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107221892&doi=10.5999%2faps.2020.01326&partnerID=40&md5=aa0494020a0ebeb30f44734693a88382 |
Division of Plastic, Reconstructive, and Aesthetic Surgery, Department of Surgery, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Putri, N.M., Division of Plastic, Reconstructive, and Aesthetic Surgery, Department of Surgery, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Tunjung, N., Division of Plastic, Reconstructive, and Aesthetic Surgery, Department of Surgery, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Sadikin, P.M., Division of Plastic, Reconstructive, and Aesthetic Surgery, Department of Surgery, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Background Various methods have been described to close large meningomyelocele defects, but no technique has been proven superior to others. This study presents cases of meningomyelocele defect closure with a keystone-design perforator island flap. Methods A retrospective study was performed on 14 patients with meningomyelocele defects closed using various types of keystone flaps. Results The median age of the patients at surgery was 10.5 days (range, 1–369 days) and the average defect size was 22.5 cm2 (range, 7.1–55.0 cm2). The average operative time for defect closure was 89.6 minutes (range, 45–120 minutes). Type IV bilateral keystone flaps were used for four defects, type IV unilateral flaps for six defects, type IIA flaps for two defects, and type III flaps for two defects. Conclusions All the defects healed completely with no major complications. The keystonedesign perforator island flap is a reliable, easy, and fast technique to close large meningomyelocele defects. © 2021 The Korean Society of Plastic and Reconstructive Surgeons. |
Island flaps; Meningomyelocele; Perforator flaps; Plastic; Surgery; Surgical flaps |
adult; aged; Article; child; clinical article; clinical outcome; defect size; disease severity; female; human; island flap; keystone design perforator island flap; length of stay; lumbar spine; male; operation duration; perforator flap; plastic surgery; preschool child; retrospective study; thoracolumbar spine; very elderly; wound closure; young adult |
Korean Society of Plastic and Reconstructive Surgeons |
22346163 |
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Article |
Q2 |
509 |
9924 |
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805 |
Wahid M.H., Findyartini A., Soemantri D., Mustika R., Felaza E., Steinert Y., Samarasekera D.D., Greviana N., Hidayah R.N., Khoiriyah U., Soeselo D.A. |
57192887722;56543777300;36640659100;57220273147;57217487889;7003537985;6506358769;57197709749;57219977261;56803884800;57199998747; |
Professional identity formation of medical teachers in a non-Western setting |
2021 |
Medical Teacher |
43 |
8 |
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868 |
873 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85106243417&doi=10.1080%2f0142159X.2021.1922657&partnerID=40&md5=fbc77286f37d3aa77b3991698ebc01ec |
Department of Medical Education and Medical Education Center Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Institute of Health Sciences Education, Faculty of Medicine and Health Sciences, McGill University, Montreal, Canada; Center for Medical Education (CenMED), Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Centre for Development of Teaching and Learning, National University of Singapore, Singapore, Singapore; Department of Medical Education and Bioethics, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia; Faculty of Medicine, Medical Education Unit, Universitas Islam Indonesia, Yogyakarta, Indonesia; Medical Education Unit, School of Medicine and Health Sciences, Universitas Katolik Atma Jaya, Jakarta, Indonesia |
Wahid, M.H., Department of Medical Education and Medical Education Center Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Findyartini, A., Department of Medical Education and Medical Education Center Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Soemantri, D., Department of Medical Education and Medical Education Center Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Mustika, R., Department of Medical Education and Medical Education Center Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Felaza, E., Department of Medical Education and Medical Education Center Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Steinert, Y., Institute of Health Sciences Education, Faculty of Medicine and Health Sciences, McGill University, Montreal, Canada; Samarasekera, D.D., Center for Medical Education (CenMED), Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, Centre for Development of Teaching and Learning, National University of Singapore, Singapore, Singapore; Greviana, N., Department of Medical Education and Medical Education Center Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Hidayah, R.N., Department of Medical Education and Bioethics, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia; Khoiriyah, U., Faculty of Medicine, Medical Education Unit, Universitas Islam Indonesia, Yogyakarta, Indonesia; Soeselo, D.A., Medical Education Unit, School of Medicine and Health Sciences, Universitas Katolik Atma Jaya, Jakarta, Indonesia |
Introduction: Understanding and supporting professional identity formation (PIF) among medical teachers has become increasingly important in faculty development programs. In this study, we explored medical teachers’ PIF in Indonesia. Methods: We conducted a qualitative descriptive study using focus group discussions (FGDs) at four medical schools in Indonesia. Basic science and clinical teachers from four different schools were selected to participate. Data were transcribed, coded, and analysed to develop themes and subthemes. Results: Seventeen FGDs were completed, involving 60 basic science and 59 clinical teachers. Four major themes regarding the formation of medical teachers’ professional identity emerged: an internal dialogue between intrinsic values and external influences, empowerment through early socialization, experiential workplace learning, and envisioning the future. The PIF process was similar for basic science and clinical teachers. Conclusion: Our findings suggested that PIF among medical teachers in a non-Western setting is a continuous and dynamic process that is shaped by key socialization factors (e.g. role models, workplace learning, peer support), with significant influences from religious beliefs, family values, and societal recognition. Faculty development programs should consider the dynamic and continuous nature of PIF among medical teachers and encourage clinicians and basic scientists to explore their values and beliefs, realize their goals, and envision their future. © 2021 Informa UK Limited, trading as Taylor & Francis Group. |
professionalism; roles of teacher; Staff development |
article; empowerment; genetic transcription; human; Indonesia; learning; medical school; peer group; personnel management; professionalism; religion; socialization; teacher; workplace; medical school; qualitative research; social behavior; university; Faculty; Humans; Learning; Qualitative Research; Schools, Medical; Social Identification |
Taylor and Francis Ltd. |
0142159X |
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33989110 |
Article |
Q1 |
1355 |
2689 |
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819 |
Putri A.S., Soedarsono N., Nehemia B., Atmadja D.S., Ubelaker D.H. |
57223021361;14049161500;57204102056;6507824506;7003416830; |
Age estimation of individuals aged 5–23 years based on dental development of the Indonesian population |
2021 |
Forensic Sciences Research |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85104502186&doi=10.1080%2f20961790.2021.1886648&partnerID=40&md5=b3c0a614893fe57774dae608436d737a |
Department of Oral Biology, Division of Forensic Odontology, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia; Department of Dento-Maxillofacial Radiology, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia; Department of Forensic Medicine and Medico-legal, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Anthropology, National Museum of Natural History, Smithsonian Institution, Washington, DC, United States |
Putri, A.S., Department of Oral Biology, Division of Forensic Odontology, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia; Soedarsono, N., Department of Oral Biology, Division of Forensic Odontology, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia; Nehemia, B., Department of Dento-Maxillofacial Radiology, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia; Atmadja, D.S., Department of Forensic Medicine and Medico-legal, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Ubelaker, D.H., Department of Anthropology, National Museum of Natural History, Smithsonian Institution, Washington, DC, United States |
Dental development can be used to estimate age for forensic purposes. However, most of the currently available methods are less reliable for the Indonesian population due to population variability. This study presents a new method and evaluates other methods that utilize dental development to estimate the age of Indonesian people. Panoramic radiographs of 304 young Indonesian people aged 5–23 years old were analysed for deciduous tooth root resorption, permanent tooth calcification, and eruption. The extent of tooth root resorption was determined based on AlQahtani’s modified Moorrees et al. method. Tooth calcification was classified based on a modified Demirjian et al. method. Tooth eruption was evaluated based on AlQahtani’s modified Bengston system. The sequence of tooth root resorption, and permanent tooth calcification and eruption were grouped into 19 age categories (from 5–23 years old) in an atlas. The differences between males and females, between maxillary and mandibular teeth, and between right and left teeth were also analysed. There were minimal significant differences of tooth development between males and females, and between the right and left teeth (P > 0.05), while the maxillary and mandibular dental development was significantly different (P < 0.05). The newly developed atlas showed the development of the right side of maxillary and mandibular tooth of combined sex of Indonesian population. Another 34 panoramic radiographs of known-age and sex individuals from Indonesia were assessed using the newly developed Atlas of Dental Development in the Indonesian Population, Ubelaker’s Dental Development Chart, The London Atlas of Human Tooth Development and Eruption by AlQahtani, and the Age Estimation Guide-Modern Australia population by Blenkin-Taylor. Accuracy was assessed by comparing estimated age to actual chronological age using the Bland-Altmand test. Results show that the smallest range of error was found in the Atlas of Dental Development in the Indonesian Population (−0.969 to 1.210 years), followed by The London Atlas of Human Tooth Development and Eruption by AlQahtani (−2.013 to 1.990 years), the Age Estimation Guide-Modern Australia population by Blenkin-Taylor (−2.495 to 2.598 years), the Dental Development Chart by Ubelaker (−2.960 to 3.289 years). These findings show that the Atlas of Dental Development constructed in this study performs better than the other three methods and presents greater accuracy of age estimation in the Indonesian population. Key points •Dental development such as deciduous tooth root resorption, permanent tooth calcification, and tooth eruption can be used to estimate age for forensic purposes. •The development of the teeth are influenced by genetic, ethnicity, and sex, therefore an age estimation method must be constructed based on the same population. •There were minimal significant differences in tooth development between male and female, and between right and left teeth, but there was significant difference between maxillary and mandibular teeth. •The Atlas of Dental Development in the Indonesian Population constructed in this study allowed more accurate age estimation of the Indonesian sample than the other methods tested. Supplemental data for this article is available online at https://doi.org/10.1080/20961790.2021.1886648. © 2021 The Author(s). Published by Taylor & Francis Group on behalf of the Academy of Forensic Science. |
age estimation; forensic odontology; Forensic sciences; root resorption; tooth calcification; tooth eruption |
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Taylor and Francis Ltd. |
20961790 |
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Article |
Q1 |
729 |
6779 |
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