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Widaty S., Sutarjo A.S., Wahid M.H., Darmawan I., Sitohang I.B.S. |
57208261546;57221634021;57192887722;57395174200;56734569200; |
The association between Malassezia spp. And pruritus in facial acne vulgaris |
2021 |
Journal of Pakistan Association of Dermatologists |
31 |
3 |
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391 |
397 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85122215594&partnerID=40&md5=d681f660e92c0b469e87702a23617193 |
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Dermatology and Venereology, Dharmais Cancer Hospital-National Cancer Center, Jakarta, Indonesia; Department of Clinical Microbiology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Widaty, S., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Sutarjo, A.S., Department of Dermatology and Venereology, Dharmais Cancer Hospital-National Cancer Center, Jakarta, Indonesia; Wahid, M.H., Department of Clinical Microbiology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Darmawan, I., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Sitohang, I.B.S., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Background Acne vulgaris (AV) is a chronic inflammatory condition involving the pilosebaceous unit. Recent studies have shown that itching of mild-to-moderate severity is relatively common in patients with acne. Malassezia spp. is normal flora of skin surface, and can be found in acne lesions. Aim: To clarify the relationship between Malassezia spp. in facial acne lesions and their association with pruritus symptom. Methods This is a cross-sectional study conducted at dermatology and venereology outpatient clinic in a tertiary hospital in Indonesia. We recruited subjects with at least four inflammatory and four noninflammatory facial acne lesions. Acne was graded using Lehmann's criteria, and pruritus was graded using visual analog scale (VAS). Follicular content of acne lesions was collected for microscopic examination and fungal culture. Results Of the 120 subjects, 46 (38.3%) reported experiencing itching in acne lesions. Pruritus was more common in patients with mild AV. Among those with pruritus, fungal spore was found in 60.6% subjects. There was no statistically significant difference in terms of the presence and severity of pruritus and presence of Malassezia spp. determined by culture (p=0.332; 0.317). Conclusion Pruritus may accompany facial acne lesions. In this study, the presence and severity of pruritus did not correlate with the presence of Malassezia spp. in facial acne lesions. © 2021 Pakistan Association of Dermatologists. All rights reserved. |
Acne vulgaris; Fungal spores; Malassezia; Pruritus; Skin disease |
anti acne agent; acne vulgaris; adolescent; adult; Article; controlled study; cross-sectional study; disease association; disease severity; female; fungus culture; fungus spore; human; human tissue; Indonesia; major clinical study; Malassezia; male; microscopy; nonhuman; outpatient department; skin pruritus; tertiary care center; visual analog scale |
Pakistan Association of Dermatologists |
15609014 |
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Article |
Q4 |
129 |
25503 |
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14 |
Kalaij A.G.I., Dirjayanto V.J., Yusuf S.M., Nelwan E.J. |
57223906853;57404619000;57359274400;14527452900; |
Immunogenicity and safety of adenovirus-based vector vaccines for COVID-19: a systematic review and meta-analysis |
2021 |
Medical Journal of Indonesia |
30 |
4 |
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264 |
278 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123701532&doi=10.13181%2fmji.oa.215559&partnerID=40&md5=480b6760fb0761aee17ad344ee18a3ce |
Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Infectious Disease and Immunology Research Center, Indonesia Medical and Education Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Kalaij, A.G.I., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Dirjayanto, V.J., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Yusuf, S.M., Infectious Disease and Immunology Research Center, Indonesia Medical and Education Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Nelwan, E.J., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
BACKGROUND Despite various research on vaccine development, severe acute respiratory syndrome coronavirus 2 infection continues to spread. Thus, developing a more effective vaccine for production and clinical efficacy is still in high demand. This review aimed to assess the immunogenicity and safety of adenovirus-based vector vaccines (Ad-vaccines) including Ad5-vectored, ChAdOx1 nCoV-19, rAd26-S or rAd5-S, and Ad26.COV2.S as the promising solutions for COVID-19. METHODS We conducted a systematic review and meta-analysis of clinical trials based on the preferred reporting items for systematic reviews and meta-analyses guidelines through PubMed, Scopus, Cochrane, and EBSCOhost until August 17, 2021. We implemented inclusion and exclusion criteria and assessed the studies using the US National Toxicology Program’s Office of Health Assessment and Translation risk of bias rating tool for human and animal studies. Pooled estimates of odds ratio (OR) were analyzed using fixed-effect model. RESULTS This systematic review yielded 12 clinical studies with a total of 75,105 subjects. Although the studies were heterogeneous, this meta-analysis showed that Ad-vaccine significantly increased protection and immune response against COVID-19 with a pooled efficacy of 84.68% compared to placebo (p<0.00001). Forest plot also indicated that Ad-vaccine conferred protection against moderate to severe COVID-19 with a pooled OR of 0.26 (p<0.00001). Ad-vaccine had also shown a good safety profile with local site pain and fever as the most common side effects. CONCLUSIONS Ad-vaccine had shown a good immunogenicity for COVID-19 with a good pooled efficacy and was proven safe for COVID-19 patients. © 2021 Authors. |
Adenovirus vaccine; COVID-19; Immunogenicity; Safety; SARS-CoV-2 |
adenovirus vaccine; vector vaccine; Article; comparative effectiveness; coronavirus disease 2019; drug delivery system; drug efficacy; drug safety; genetic reassortment; human; immune response; immunogenicity; meta analysis; outcome assessment; practice guideline; risk assessment; sensitivity analysis; seroconversion; systematic review; vaccination |
Faculty of Medicine, Universitas Indonesia |
08531773 |
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Article |
Q4 |
164 |
21905 |
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15 |
Lukman P.R., Saputra A., Elvira S.D., Heriani, Almasyhur A.F., Putri L.A., Alfonso C.A., Noviasari R.R. |
55981460300;57431501600;57192888533;57431901600;57203618023;57432304200;7004331573;57431697600; |
Efficacy of video-based psychotherapy in reducing psychological distress COVID-19 patients treated in isolation ward |
2021 |
Medical Journal of Indonesia |
30 |
4 |
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250 |
255 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123688789&doi=10.13181%2fmji.oa.215473&partnerID=40&md5=05a78950b452a144715a92b0e790ed60 |
Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Psychiatry, Columbia University Irving Medical Center, New York, United States; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Lukman, P.R., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Saputra, A., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Elvira, S.D., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Heriani, Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Almasyhur, A.F., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Putri, L.A., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Alfonso, C.A., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Psychiatry, Columbia University Irving Medical Center, New York, United States; Noviasari, R.R., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
BACKGROUND Hospitalized patients with COVID-19 experience isolation during treatment, which may cause psychological distress. Thus, alternative ways to deliver psychological support are needed when face-to-face therapy is not possible. This study aimed to investigate the efficacy of video-based psychotherapy in reducing distress in COVID-19 patients treated in an isolation ward. METHODS This quasi-experimental trial without a control group included 42 COVID-19 patients aged 20–59 years. Participants were recruited conveniently in the COVID-19 isolation ward in Cipto Mangunkusumo Hospital, Jakarta, Indonesia. They watched three brief psychotherapy videos including relaxation, managing thoughts and emotions, and mindfulness for approximately 30 min. The videos were created by the Department of Psychiatry, Faculty of Medicine, Universitas Indonesia. Subjective units of distress scale (SUDS) was measured before and after watching all videos. Data were analyzed using the Wilcoxon-signed rank test. RESULTS All 42 subjects finished watching the videos. 31 subjects experienced a significant median decrease in SUDS score after the intervention. The effect size of the psychotherapy videos for the SUDS score was 0.485 (95% CI 0.302 to 0.634). CONCLUSIONS Watching psychotherapy videos is effective in reducing the SUDS score for COVID-19 patients in an isolation ward. Our brief video-based psychotherapy intervention has reduced psychological distress in hospitalized COVID-19 patients with limited access to face-to-face consultations due to the risk of disease transmission. © 2021 Authors. |
COVID-19; Instructional film and audio; Patient isolation; Psychological distress; Psychotherapy |
adult; Article; clinical article; coronavirus disease 2019; distress syndrome; emotion; female; human; length of stay; male; middle aged; mindfulness; psychotherapy; quasi experimental study; questionnaire; relaxation sensation; subjective unit of distress scale; video based psychotherapy |
Faculty of Medicine, Universitas Indonesia |
08531773 |
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Article |
Q4 |
164 |
21905 |
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16 |
Hidayati E.R.N., Suharti A., Suratinoyo A.T., Zahra S.R., Nusdwinuringtyas N. |
57192909138;57430912200;57430912300;57431910100;56608215500; |
Feasibility of the modified 30-second sit-to-stand test in an isolation ward omoderate COVID-19 |
2021 |
Medical Journal of Indonesia |
30 |
4 |
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306 |
310 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123687687&doi=10.13181%2fmji.bc.215477&partnerID=40&md5=46eb378aa55f3d5a5501b012c001442f |
Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Universitas Indonesia, Universitas Indonesia Hospital, Depok, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Hidayati, E.R.N., Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Universitas Indonesia, Universitas Indonesia Hospital, Depok, Indonesia; Suharti, A., Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Universitas Indonesia, Universitas Indonesia Hospital, Depok, Indonesia; Suratinoyo, A.T., Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Universitas Indonesia, Universitas Indonesia Hospital, Depok, Indonesia; Zahra, S.R., Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Universitas Indonesia, Universitas Indonesia Hospital, Depok, Indonesia; Nusdwinuringtyas, N., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
BACKGROUND The recovery after prolonged immobilization during hospitalization because of COVID-19 is the primary goal of moderate to severe COVID-19 rehabilitation. Lower extremity muscle function assessment after immobilization is needed before starting mobilization. Hence, this study aimed to evaluate the feasibility of the modified 30-second sit-to-stand test (m30STS) as one of the prospective tools of functional capacity assessment in moderate COVID-19. METHODS This cross-sectional study recruited the subjects consecutively. All eligible subjects with oxygen saturation (SaO2 ) ≥95% with or without oxygen supplementation performed the m30STS following the Bohannon’s guidelines. The score of m30STS was calculated based on the number of stands completed within 30 sec. A higher score of the m30STS indicated better lower extremity function. RESULTS Mean score of m30STS was 13.3. No subjects had oxygen desaturation or increased heart rate, and no fall incidents occurred. CONCLUSIONS The m30STS is feasible and safe to evaluate lower extremity for moderate COVID-19 patients with SaO2 >95%. The absence of oxygen desaturation and increase in heart rate showed no increased oxygen consumption during the test. © 2021 Authors. |
COVID-19; Functional capacity; Modified 30-second sit-to-stand tes |
adult; Article; coronavirus disease 2019; cross-sectional study; female; functional status; heart rate; hospital department; human; isolation; length of stay; major clinical study; male; middle aged; mobilization; muscle strength; oxygen desaturation; oxygen saturation; prospective study; sit-to-stand test |
Faculty of Medicine, Universitas Indonesia |
08531773 |
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Article |
Q4 |
164 |
21905 |
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17 |
Hidayat R., Asmaniar F., Priambodo A., Mesiano T., Kurniawan M., Rasyid A., Har S. |
57225289998;57219959732;57431511100;57204830976;57432111000;56703146700;57431910000; |
Endovascular treatment of an unruptured ophthalmic artery aneurysm with a flow diverter: A case report |
2021 |
Medical Journal of Indonesia |
30 |
4 |
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297 |
300 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123683324&doi=10.13181%2fmji.cr.204899&partnerID=40&md5=25be03988554b8a69e078a04d109a317 |
Department of Neurology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Hidayat, R., Department of Neurology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Asmaniar, F., Department of Neurology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Priambodo, A., Department of Neurology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Mesiano, T., Department of Neurology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Kurniawan, M., Department of Neurology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rasyid, A., Department of Neurology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Har, S., Department of Neurology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
An unruptured aneurysm is often asymptomatic or present without neurological deficits, causing severe morbidity. However, the potential of this defect to rupture requires proper management. Herein, we report a case of an unruptured saccular aneurysm of the ophthalmic artery with initial clinical seizures. The patient was treated by flow diversion which redirects the blood flow that normally leads to the protrusion of the aneurysm back to the main vessel. Flow diversion is chosen because it is less risky and has a faster recovery time than other treatment options, but it is more expensive than others. Although this technology is not new, there is no report on its implementation in Indonesia. The patient was prescribed antiplatelet treatment for at least 6 months post-treatment, then she showed no sign of seizure or new focal neurological deficits 4 months post-treatment. The patients were expected to undergo digital subtraction angiography evaluation 6 months after flow diversion treatment, but it has not been performed due to the coronavirus disease 2019 pandemic. © 2021 Authors. |
Aneurysm; Computed tomography angiography; Digital subtractangiography; Endovascular; Ophthalmic artery; Seizures |
acetylsalicylic acid; candesartan; clopidogrel; phenytoin; adult; aneurysm; Article; blindness; blood flow; case report; clinical article; coil embolization; computed tomographic angiography; computer assisted tomography; coronavirus disease 2019; digital subtraction angiography; electroencephalography; endovascular surgery; epilepsy; female; follow up; human; hypertension; internal carotid artery; middle aged; neurologic disease; nuclear magnetic resonance imaging; ophthalmic artery; pandemic; saccular aneurysm; seizure; stenosis; thorax radiography; thrombocyte; vertebral artery |
Faculty of Medicine, Universitas Indonesia |
08531773 |
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Article |
Q4 |
164 |
21905 |
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18 |
Firdaus R., Theresia S., Austin R., Tiara R. |
57423039300;57222095380;57422434500;57422587800; |
Propofol effects in rodent models of traumatic brain injury: A systematic review |
2021 |
Asian Biomedicine |
15 |
6 |
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253 |
265 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123275403&doi=10.2478%2fabm-2021-0032&partnerID=40&md5=fdc2eb2da5eaacf73d60546fd4a9fc72 |
Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia |
Firdaus, R., Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia; Theresia, S., Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia; Austin, R., Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia; Tiara, R., Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia |
Background: Traumatic brain injury (TBI) causes high mortality and disability worldwide. Animal models have been developed to explore the complex processes in TBI. Propofol is used to manage head injuries during surgical intervention and mechanical ventilation in patients with TBI. Many studies have investigated the neuroprotective effect of propofol on TBI. However, other studies have shown neurotoxic effects. Objectives: To review systematically the literature regarding the neuroprotective and neurotoxic effects of propofol in rodent models of TBI. Methods: Data from rodents as models of TBI with propofol as one of the intervention agents, and/or comparing the neuroprotective effects of propofol with the other substances in rodent models of TBI, were obtained from PubMed, EBSCO Host, and ProQuest databases. The PRISMA 2020 statement recommendations were followed and research questions were developed based on PICOS guidelines. Data was extracted from the literature using a standardized Cochrane method. Results: We analyzed data from 12 articles on physiological changes of experimental animals before and after trauma, the effects of propofol administration, and the observed neurotoxic effects. The effects of propofol administration were observed in terms of changes in traumatic lesion volume, the release of antioxidants and inflammatory factors, and the neurological function of rodent models of TBI. Conclusion: Propofol has neuroprotective and neurotoxic effects via several mechanisms, and various doses have been used in research to determine its effects. The timing of administration, the dose administered, and the duration of administration contribute to determine the effect of propofol in rodent models of TBI. However, the doses that produce neuroprotective and neurotoxic effects are not yet clear and further research is needed to determine them. © 2021 Riyadh Firdaus et al., published by Sciendo. |
anesthetics; brain injuries, traumatic; neuroprotection; propofol; Rodentia |
calpain; carbon dioxide; catalase; citicoline; diazepam; erythropoietin; fentanyl; glucose; immunoglobulin enhancer binding protein; interleukin 1beta; interleukin 6; isoflurane; ketamine; malonaldehyde; mitogen activated protein kinase p38; morphine; nitric oxide; oxygen; pentobarbital; propofol; semaphorin; superoxide dismutase; tumor necrosis factor; xanthine oxidase; adult; antiinflammatory activity; antioxidant activity; arterial carbon dioxide tension; arterial oxygen tension; blood pH; brain edema; brain injury; Cochrane Library; combination drug therapy; controlled study; core temperature; diffuse brain injury; dose response; drug megadose; female; glucose blood level; head injury; heart rate; hematocrit; lesion volume; lipid peroxidation; low drug dose; male; mean arterial pressur |
Sciendo |
19057415 |
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Review |
Q4 |
178 |
20816 |
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31 |
Nusanti S., Dearaini, Bani A.P., Kartasasmita A.S., Ichsan A.M., Virgana R., Anggraini N., Rahayu T., Irfani I., Edwar L., Rifada M., Yudantha A.R., Ismail M.A., Komaratih E., Wildan A., Knoch A.M.H. |
57189727162;57386841000;53663268800;37002851300;57218514954;56922099400;57387397200;57208305374;57201131541;55695047800;55249679300;55489644900;57386650700;57204192624;57205025156;57386841100; |
Delivering a modified continuous objective structured clinical examination for ophthalmology residents through a hybrid online method |
2021 |
Korean Journal of Medical Education |
33 |
4 |
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419 |
430 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85121800362&doi=10.3946%2fkjme.2021.210&partnerID=40&md5=f12d396df59aa176538ef352c359c609 |
Indonesian College of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Ophthalmology, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia; Department of Ophthalmology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia; Department of Ophthalmology, Faculty of Medicine, Airlangga University, Surabaya, Indonesia; Department of Ophthalmology, Faculty of Medicine, Diponegoro University, Semarang, Indonesia |
Nusanti, S., Indonesian College of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Dearaini, Indonesian College of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Bani, A.P., Indonesian College of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Kartasasmita, A.S., Indonesian College of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Ophthalmology, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia; Ichsan, A.M., Indonesian College of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Ophthalmology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia; Virgana, R., Indonesian College of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Ophthalmology, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia; Anggraini, N., Indonesian College of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Rahayu, T., Indonesian College of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Irfani, I., Indonesian College of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Ophthalmology, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia; Edwar, L., Indonesian College of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Rifada, M., Indonesian College of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Yudantha, A.R., Indonesian College of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Ismail, M.A., Indonesian College of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Ophthalmology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia; Komaratih, E., Indonesian College of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Ophthalmology, Faculty of Medicine, Airlangga University, Surabaya, Indonesia; Wildan, A., Indonesian College of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Ophthalmology, Faculty of Medicine, Diponegoro University, Semarang, Indonesia; Knoch, A.M.H., Indonesian College of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Ophthalmology, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia |
Since coronavirus disease 2019 was declared a global pandemic by the World Health Organization, it has become a challenging situation to continue medical education, including in Indonesia. The situation prohibited face-to-face (direct) educational activities in clinical settings, therefore also postponing examinations involving especially procedural skills. Adaptations were urgently needed to maintain the delivery of high-stake examinations to sustain the number of ophthalmology graduates and the continuation of eye health service. Objective structured clinical examination (OSCE) has been one of our widely used method to assess clinical competencies for ophthalmology residents, and is the one method that involves gatherings, close contact of examiners, examinees and patients, therefore the most difficult to adjust. Pandemic challenges brought technical changes in our delivering the OSCE to online, maximizing digital platforms of meetings, while still concerned to guarding the safety of candidates, patients and staffs. OSCE scenarios were also made as timely efficient as possible by changing continuous station models to a cascade one. The purpose of this article is to document our experience in conducting a feasible and reproducible OSCE in this pandemic era filled with limitations. © The Korean Society of Medical Education. All rights reserved. |
COVID-19; Education; Internship and residency; Methods; Ophthalmology / education |
clinical competence; education; health service; human; medical education; ophthalmology; Clinical Competence; COVID-19; Educational Measurement; Health Services; Humans; Internship and Residency; Ophthalmology; SARS-CoV-2 |
Korean Society of Medical Education |
2005727X |
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34875158 |
Article |
Q4 |
175 |
21057 |
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32 |
Yo E.C., Witjaksono A.N., Fitriani D.Y., Werdhani R.A., Parikesit D. |
57213188908;57224351398;57224589606;57189088848;57163830300; |
Evaluating knowledge retention and perceived benefits of medical webinar for professional development among Indonesian physicians |
2021 |
Korean Journal of Medical Education |
33 |
4 |
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381 |
391 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85121761218&doi=10.3946%2fkjme.2021.206&partnerID=40&md5=88879a0b2b85137bc0337e9c3aa3de9b |
Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Ophthalmology Medical Staff Group, Universitas Indonesia Hospital, Universitas Indonesia, Depok, Indonesia; Occupational Medicine Staff Group, Universitas Indonesia Hospital, Universitas Indonesia, Depok, Indonesia; Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Urology Medical Staff Group, Universitas Indonesia Hospital, Universitas Indonesia, Depok, Indonesia |
Yo, E.C., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Witjaksono, A.N., Ophthalmology Medical Staff Group, Universitas Indonesia Hospital, Universitas Indonesia, Depok, Indonesia; Fitriani, D.Y., Occupational Medicine Staff Group, Universitas Indonesia Hospital, Universitas Indonesia, Depok, Indonesia, Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Werdhani, R.A., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Parikesit, D., Urology Medical Staff Group, Universitas Indonesia Hospital, Universitas Indonesia, Depok, Indonesia |
Purpose: To assess knowledge retention of physicians after participating in a webinar series and its perceived benefits on daily practice and career development. Methods: The webinar series comprised six separate webinars about daily practice. Online questionnaires were sent to all participating physicians via email 3 months after the webinars. The questionnaire assessed knowledge retention through the difference between initial and follow-up post-test as well as the webinar series' benefits on daily practice and career development. Participants' demographic information, including their age, gender, education, year of graduation, and work details, were collected to compare outcomes between demographic groups. Results: A total of 689 responses were gathered, and 622 were analyzed. At follow-up, the median knowledge score was significantly lower than the initial median knowledge score (Z=-6.973, p<0.001). Participants' perception of the webinar series' benefits on daily practice and career development was very positive. A significant weak negative correlation was found between age and knowledge score at follow-up (rs=-0.157, p<0.001). Physicians who graduated more recently and worked for less than 3 years scored significantly higher on knowledge tests at follow-up. Meanwhile, perception score towards webinar series' benefits on daily practice was significantly higher among physicians with more extended work history. Male physicians scored significantly higher on perception score towards webinar series' benefits on career development. Conclusion: Online continuing medical education programs like webinars can encourage physicians to maintain their competence, but further research on improving knowledge retention over time is necessary. Overall, physicians perceived webinars to be beneficial for their professional development. © The Korean Society of Medical Education. All rights reserved. |
Continuing medical education; Knowledge retention; Physicians; Professional development; Videoconference |
human; Indonesia; male; medical education; physician; questionnaire; Education, Medical, Continuing; Humans; Indonesia; Male; Physicians; Surveys and Questionnaires |
Korean Society of Medical Education |
2005727X |
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34875154 |
Article |
Q4 |
175 |
21057 |
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35 |
Dwijayanti A., Fitrianto A.I., Boediono A., Setiati S., Suyatna F.D. |
55743787900;57377401300;9040094200;14325991900;56039633100; |
Mesenchymal stem cells administration in aged male rats increases testosterone and lower TNF-α levels |
2021 |
International Medical Journal |
28 |
6 |
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601 |
603 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85121461058&partnerID=40&md5=bbf2100ed3003ab64dcb298ba7d9f029 |
Doctoral Program in Biomedical Science, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Medical Pharmacy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Anatomy, Physiology, and Pharmacology, Faculty of Veterinary Medicine, Bogor Agricultural University, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Dwijayanti, A., Doctoral Program in Biomedical Science, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Medical Pharmacy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Fitrianto, A.I., Department of Anatomy, Physiology, and Pharmacology, Faculty of Veterinary Medicine, Bogor Agricultural University, Indonesia; Boediono, A., Department of Anatomy, Physiology, and Pharmacology, Faculty of Veterinary Medicine, Bogor Agricultural University, Indonesia; Setiati, S., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Suyatna, F.D., Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Background: Treatment for sex hormone depletion along with chronic inflammation would be beneficial for aging males. Mesenchymal stem cells (MSC) are known for their immunomodulatory activities and differentiation ability in regenerative medicine. Whether MSC could influence both testosterone and pro-inflammatory marker in aging males is uncertain. This study aimed to explore the effects of human umbilical mesenchymal stem cell (hUCMSC) on testosterone, tumor necrosis factor-alpha (TNF-α), and creatinine levels in aged rats. Methods: The hUCMSC was administered to aged male Sprague-Dawley rats (24 months old). After four injections of 1 mil-lion per kg body weight in 3-month intervals, the rats were sacrificed, and serum was collected for biochemical examinations. Results: The hUCMSC administrations increased the testosterone level almost three-fold and decreased the TNF-α level. Moreover, the high testosterone level was strongly correlated with low TNF-α level (p = 0.013; r =-0.863) in aged male rats. These results were following our previous report, which showed that the hUCMSC increased the number of Leydig cells. Serum creatinine levels in the treatment group were slightly increased but were still within the normal limit. Conclusion: The hUCMSC treatment in aged male rats tends to increase testosterone levels and lower TNF-α levels. © 2021 Japan University of Health Sciences & Japan International Cultural Exchange Foundation. |
Aging; Mesenchymal stem cell; Testosterone; TNF-α |
creatinine; sex hormone; testosterone; tumor necrosis factor; aged; aging; animal cell; animal experiment; animal model; animal tissue; Article; body weight; controlled study; creatinine blood level; creatinine clearance; female; gene expression; Leydig cell; male; mesenchymal stem cell; nonhuman; protein expression; rat; regenerative medicine; Sprague Dawley rat; testosterone blood level |
Japan International Cultural Exchange Foundation |
13412051 |
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Article |
Q4 |
183 |
20490 |
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