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No records
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46 |
Martika W., Dilogo I.H., Setyawan R. |
57221741247;56161962800;57206249736; |
Functional outcome in scapular fracture treatment evaluation with 2-year follow-up in Cipto Mangunkusumo Hospital |
2021 |
International Journal of Surgery Open |
37 |
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100425 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119256972&doi=10.1016%2fj.ijso.2021.100425&partnerID=40&md5=b50a45ce664d7aea0b7dc9549bdde380 |
Department of Orthopaedics and Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Adult Reconstruction, Hip, and Knee Division, Department of Orthopaedics and Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Martika, W., Department of Orthopaedics and Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Dilogo, I.H., Adult Reconstruction, Hip, and Knee Division, Department of Orthopaedics and Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Setyawan, R., Department of Orthopaedics and Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Background: Standard treatment of scapular fractures is still controversial. There was no consensus for the best indication in surgical management and therapeutic choice of the scapular fracture. This study aim is to evaluate both radiological characteristics and functional outcomes between patients with scapular fracture treated with conservative and operative management. Methods: We did a case series study of 19 patients with scapular fractures between 2012 and 2017. Nine patients were treated with open reduction internal fixation and 10 patients were treated conservatively. We evaluated radiological outcome using degree of Glenopolar Angle (GPA), angulation, and medialization through anteroposterior, lateral, and scapular Y projection, functional outcome using DASH scores, and complications in 2-year follow-up. Result: The mean patient age was 46.3 ± 18.4 years in the conservative group and 42.7 ± 11.5 years in the operative group. Fracture pattern was classified using Zdravkovic and Damholt (ZD) classification. DASH Score was excellent with 9.5 ± 2.1 points in conservative group and 6.0 ± 2.5 points in operative group with insignificant difference. There was significant difference in GPA and medialization. This is supported by functional outcome of operative group which is higher compared to conservative treatment insignificantly. Conclusion: Operative treatment resulted high functional outcome and minimal complications compared to the conservative group. Operative treatment was recommended for scapular fractures that are displaced more than 9 mm and/or angulated more than 40°. Level of evidence: II, therapeutic study. © 2021 The Authors |
Conservative treatment; DASH score; Glenopolar angle; Scapular fracture; Surgical treatment; Zdravkovic and damholt classification |
adult; clinical article; clinical outcome; conservative treatment; controlled study; Disabilities of the Arm, Shoulder and Hand (score); female; follow up; functional status; human; intermethod comparison; intraoperative period; male; open reduction (procedure); orthopedic surgery; osteosynthesis; outcome assessment; preoperative evaluation; scapula fracture; Short Survey; shoulder radiography; treatment indication; x-ray computed tomography |
Elsevier Ltd |
24058572 |
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Short Survey |
Q4 |
187 |
20224 |
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59 |
Adriansyah I.A., Afriansyah A., Siregar M.A.R., Purnomo N., Mirza H., Seno D.H. |
57255172900;57190688768;57255058200;57255293100;57208513330;57255640300; |
Efficacy of holmium laser enucleation of the prostate in patients with detrusor underactivity: systematic review and meta-analysis |
2021 |
African Journal of Urology |
27 |
1 |
128 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114753119&doi=10.1186%2fs12301-021-00230-1&partnerID=40&md5=a5780c3ae26d7da14412977dd81e01f7 |
Department of Urology, Faculty of Medicine, Universitas Indonesia, Jl. Diponegoro No. 71, Salemba, Jakarta Pusat, Jakarta, DKI Jakarta 10430, Indonesia; Division of Urology, Department of Surgery, Persahabatan Hospital, Jl. Persahabatan Raya No. 1, Pulo Gadung, Jakarta Timur, Jakarta, DKI Jakarta 13230, Indonesia |
Adriansyah, I.A., Department of Urology, Faculty of Medicine, Universitas Indonesia, Jl. Diponegoro No. 71, Salemba, Jakarta Pusat, Jakarta, DKI Jakarta 10430, Indonesia; Afriansyah, A., Division of Urology, Department of Surgery, Persahabatan Hospital, Jl. Persahabatan Raya No. 1, Pulo Gadung, Jakarta Timur, Jakarta, DKI Jakarta 13230, Indonesia; Siregar, M.A.R., Division of Urology, Department of Surgery, Persahabatan Hospital, Jl. Persahabatan Raya No. 1, Pulo Gadung, Jakarta Timur, Jakarta, DKI Jakarta 13230, Indonesia; Purnomo, N., Division of Urology, Department of Surgery, Persahabatan Hospital, Jl. Persahabatan Raya No. 1, Pulo Gadung, Jakarta Timur, Jakarta, DKI Jakarta 13230, Indonesia; Mirza, H., Division of Urology, Department of Surgery, Persahabatan Hospital, Jl. Persahabatan Raya No. 1, Pulo Gadung, Jakarta Timur, Jakarta, DKI Jakarta 13230, Indonesia; Seno, D.H., Division of Urology, Department of Surgery, Persahabatan Hospital, Jl. Persahabatan Raya No. 1, Pulo Gadung, Jakarta Timur, Jakarta, DKI Jakarta 13230, Indonesia |
Background: Benign prostatic hyperplasia (BPH) is commonly found in the aging male. Treatment of BPH can be in form of conservative or surgical intervention. Transurethral resection of the prostate (TURP) is the gold-standard treatment for BPH according to the guideline. However, there is no evidence that there is a benefit for TURP in patients with detrusor underactivity (DUA). Holmium laser enucleation (HoLEP) is theorized to have a better outcome due to its property of complete prostate enucleation. Therefore, this meta-analysis aims to determine the benefit of HoLEP for BPH patients with DUA. Main body: We performed systematic literature searching from five databases including PubMed, Scopus, Embase, Science Direct, and Web of Science for articles up to 31 December 2020 for relevant studies. A total of five articles are eligible for this meta-analysis. A total of 2.180 subjects participated in all of the studies included. Two studies comparing patients with and without DUA that was treated with HoLEP, two studies comparing HoLEP with other surgical approaches for BPH, and one study comparing both parameters. IPSS score reduction is significantly higher in the patients with DUA (Mean Difference = 3.28, 95% CI 1.91 to 4.64, p < 0.01). Qmax and PVR are not significantly different between both groups. HoLEP also showed better improvement in IPSS and Qmax compared to TURP (IPSS: Mean Difference = -4.80, 95% CI − 7.83 to − 1.77, p = 0.002; Qmax: Mean Difference = 4.20, 95% CI 0.58 to 7.82, p = 0.02) and PVP (IPSS: Mean Difference = − 2.47, 95% CI − 4.47 to − 0.47, p = 0.02; Qmax: Mean Difference = 2.31, 95% CI 0.34 to 4.28, p = 0.02). Conclusion: HoLEP showed better improvement in IPSS scores in patients with DUA. HoLEP can be considered to be performed in the BPH patients with DUA for better outcomes for the patients. © 2021, The Author(s). |
Benign prostatic hyperplasia; Detrusor underactivity; HoLEP; Laser enucleation; Surgical outcome |
clinical effectiveness; Embase; enucleation; human; hypotonic bladder; information retrieval; intermethod comparison; International Prostate Symptom Score; laser surgery; male; measurement; Medline; meta analysis; Newcastle-Ottawa scale; postvoid residual urine volume; prostate hypertrophy; prostate surgery; randomized controlled trial (topic); Review; ScienceDirect; Scopus; surgical approach; systematic review; transurethral resection; Web of Science |
Springer Science and Business Media Deutschland GmbH |
11105704 |
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Review |
Q4 |
174 |
21103 |
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60 |
Satjakoesoemah A.I., Alfarissi F., Wahyudi I., Rodjani A., Rasyid N. |
57189614677;57197871808;36341995300;6504653529;56245069300; |
Factors related to the success rate of pediatric extracorporeal shock wave lithotripsy (ESWL) in Cipto Mangunkusumo Hospital: an 8-year single-center experience |
2021 |
African Journal of Urology |
27 |
1 |
92 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114055813&doi=10.1186%2fs12301-021-00187-1&partnerID=40&md5=a186e20e8260339cc3e9b7f5ff9c9867 |
Department of Urology, Faculty of Medicine, Cipto Mangunkusumo General Hospital, Universitas Indonesia, Pangeran Diponegoro Street No. 71, Senen Subdistrict, Central Jakarta District, Jakarta, 10430, Indonesia |
Satjakoesoemah, A.I., Department of Urology, Faculty of Medicine, Cipto Mangunkusumo General Hospital, Universitas Indonesia, Pangeran Diponegoro Street No. 71, Senen Subdistrict, Central Jakarta District, Jakarta, 10430, Indonesia; Alfarissi, F., Department of Urology, Faculty of Medicine, Cipto Mangunkusumo General Hospital, Universitas Indonesia, Pangeran Diponegoro Street No. 71, Senen Subdistrict, Central Jakarta District, Jakarta, 10430, Indonesia; Wahyudi, I., Department of Urology, Faculty of Medicine, Cipto Mangunkusumo General Hospital, Universitas Indonesia, Pangeran Diponegoro Street No. 71, Senen Subdistrict, Central Jakarta District, Jakarta, 10430, Indonesia; Rodjani, A., Department of Urology, Faculty of Medicine, Cipto Mangunkusumo General Hospital, Universitas Indonesia, Pangeran Diponegoro Street No. 71, Senen Subdistrict, Central Jakarta District, Jakarta, 10430, Indonesia; Rasyid, N., Department of Urology, Faculty of Medicine, Cipto Mangunkusumo General Hospital, Universitas Indonesia, Pangeran Diponegoro Street No. 71, Senen Subdistrict, Central Jakarta District, Jakarta, 10430, Indonesia |
Background: ESWL is still considered as the first favorable therapeutic option for urinary stone disease with acceptable effectivity. However, factors associated with favorable outcome have not been widely studied in pediatrics due to the small number of urinary stone prevalence. The aim of this study is to evaluate the factors associated with the success rate of pediatric ESWL in our center according to immediate stone-free rate and 3-month stone-free rates. Methods: This is a retrospective cohort study of children less than 18 years who had ESWL for urolithiasis from January 2008 until August 2015. Patient’s characteristics including age, gender, BMI, stone location, stone length, stone burden, stone opacity, and number of ESWL sessions were gathered from the medical record. Nutritional status was determined according to the Centers for Disease Control and Prevention BMI curve. The outcome of this study was the factors related to the success rate in pediatric ESWL. Results: Extracorporeal shock wave lithotripsy was done for 36 patients and 39 renal units (RUs) with mean age of 13.7 ± 4.3 years old, height of 1480 ± 16.0 cm, and BMI of 20.0 ± 3. Of 36 patients included, 39 renoureteral units (RUs) and 46 ESWL sessions were recorded. The mean overall treatment was 1.2 ± 0.5 sessions with mean stone length of 11.1 ± 6.3 mm and stone burden of 116.6 ± 130.3 mm2. Within 3 months of follow-up, we recorded that the overall 3-month success rate was 100%, while the overall 3-month stone-free rate was 66.7%. Stone length (p < 0.001 and p < 0.001), stone perpendicular length (p < 0.001 and p < 0.001), and stone burden (p < 0.001 and p = 0.001) were found to be significantly associated with immediate success and 3-month stone-free status, respectively. Conclusions: ESWL is an effective and safe modality to treat pediatric urolithiasis cases. Stone length, stone perpendicular length, and stone burden were found to be associated with immediate success and 3-month stone-free status after pediatric ESWL treatment. © 2021, The Author(s). |
ESWL; Pediatric; Stone-free rate; Success rate; Urinary stone disease; Urolithiasis |
adolescent; age; Article; body mass; clinical article; cohort analysis; evaluation study; extracorporeal shock wave lithotripsy; factor analysis; female; follow up; gender; hospital; human; male; nutritional status; outcome assessment; public health service; retrospective study; urolithiasis |
Springer Science and Business Media Deutschland GmbH |
11105704 |
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Article |
Q4 |
174 |
21103 |
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90 |
Lydia A., Yassir Y., Hidayat R., Suwarto S. |
8451287200;57463407000;37067327300;8443626100; |
The Association Between Uric Acid and Symmetric Dimethylarginine Levels in the Patients Undergoing Twice-weekly Hemodialysis |
2021 |
Nephro-Urology Monthly |
13 |
4 |
e117476 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85125057044&doi=10.5812%2fNUMONTHLY.117476&partnerID=40&md5=8d20b0dc3cfeb796c8879fd9e2fd2a30 |
Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Lydia, A., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Yassir, Y., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Hidayat, R., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Suwarto, S., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Background: Uric acid (UA) levels are associated with increased risk of cardiovascular events and mortality in hemodialysis pa-tients. However, there are still conflicting data on the mechanism of increased risks related to uric acid levels. Objectives: This study assessed the association between uric acid levels and symmetric dimethylarginine (SDMA), as a marker of cardiovascular disease, in the subjects undergoing hemodialysis twice weekly. Methods: This was a cross-sectional study conducted in a tertiary hospital in Jakarta, Indonesia. We included all the adults who underwent hemodialysis twice weekly for at least three months in our hospital. Subjects already on uric acid lowering therapy, pregnant or lactating women and those with a history of malignancy were excluded. Uric acid and SDMA levels were measured at the same time in pre-dialysis venous blood samples. Bivariate analysis was performed using the Mann-Whitney U test or one-way ANOVA. Results: A total of 126 subjects were included. The median level of UA was 8.4 mg/dL (IQR: 2.6, min: 4.1, max: 13.6), and 72 subjects (57.14%) had UA levels of 8 mg/dL or higher. The median SDMA level was 535.5 (312.7) mmol/dL (min: 119.7, max: 1895.5). Subjects with UA levels >8 mg/dL had significantly higher SDMA levels compared to subjects with UA levels < 8 mg/dL (550.1 (IQR: 357.25) vs 491.35 (IQR: 181.1), P: 0.0475). Conclusions: In twice-weekly hemodialysis patients, UA levels above 8 mg/dL were associated with increased SDMA levels. © 2021, Author(s). |
Cardiovascular Risk Factors; Chronic Kidney Disease; Hemodialysis; Hyperuricemia; Uric Acid |
6 n,n' dimethylarginine; uric acid; adult; amino acid blood level; Article; cardiovascular disease; cardiovascular risk factor; cross-sectional study; diabetes mellitus; female; glomerulonephritis; hemodialysis; human; hypertension; major clinical study; male; middle aged; mortality; nutritional assessment; obesity; smoking; tertiary care center; underweight |
Kowsar Medical Institute |
22517006 |
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Article |
Q4 |
150 |
23185 |
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93 |
Zizlavsky S., Anam K., Suwento R., Rahmawati I. |
57195721920;57474576600;55743638800;57372516200; |
The effects of Goldenhar Syndrome on hearing and speech development |
2021 |
Medical Journal of Malaysia |
76 |
6 |
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946 |
949 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85121118699&partnerID=40&md5=ccde190cb788d0255d331b7adfe1295c |
Department of Otorhinolaryngology-Head & Neck Surgery, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Zizlavsky, S., Department of Otorhinolaryngology-Head & Neck Surgery, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Anam, K., Department of Otorhinolaryngology-Head & Neck Surgery, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Suwento, R., Department of Otorhinolaryngology-Head & Neck Surgery, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Rahmawati, I., Department of Otorhinolaryngology-Head & Neck Surgery, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Goldenhar syndrome is a congenital abnormality with an incidence of 1 in 5,200 to 26,500 births. This syndrome is characterized by facial asymmetry, ear malformation, and/or defects in the eyes and vertebrae. The hearing disorder manifests as both conductive or sensorineural due to the abnormalities occurring in the inner and outer ear. We report a case of a 1-year-3-month-old child presenting with left anotia and right microtia, severe bilateral conductive hearing loss, and global delayed development. The patient was also found to have a hemifacial microsomia, a secundum atrial septal defect (ASD), and a ventricular septal defect (VSD). The patient was advised to use hearing aids and participate in speech therapy. The management of this Goldenhar syndrome patient should be done comprehensively, appropriate to the abnormalities found to achieve the best result. © 2021, Malaysian Medical Association. All rights reserved. |
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anterior inferior cerebellar artery; Article; audiology; babbling; blue light; brainstem evoked response audiometry; case report; clinical article; conduction deafness; cranial nerve paralysis; dyspnea; ear malformation; electrophysiological response; face asymmetry; face deformity; Goldenhar syndrome; hearing; hearing disorder; hearing examination; hearing function; heart atrium septum defect; heart disease; heart ventricle septum defect; hemifacial microsomia; human; hyperbilirubinemia; infant; lagophthalmos; loud noise; male; micrognathia; microtia; motor development; nuclear magnetic resonance imaging; parasystolic murmur; perception deafness; ptosis (eyelid); radiodiagnosis; speech development; speech therapy |
Malaysian Medical Association |
03005283 |
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34806693 |
Article |
Q4 |
193 |
19818 |
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117 |
Umiatin, Indrasari W., Taryudi, Sari P., Mazfufah N.F., Rosadi I. |
57202292099;56069603500;57003576500;55776482300;57215595521;57204720098; |
Effect of pulse electromagnetic field exposure on the expression of lipo protein lipase (LPL) on the differentiation of mesenchymal stem cell |
2021 |
Journal of Physics: Conference Series |
2019 |
1 |
012107 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119203085&doi=10.1088%2f1742-6596%2f2019%2f1%2f012107&partnerID=40&md5=cd764de9d9b9c1287f97fb09cfd8eea2 |
Department of Physics, Faculty of Mathematics and Natural Science, Universitas Negeri Jakarta, Indonesia; Department of Electronic Engineering, Faculty of Engineering, Universitas Negeri Jakarta, Indonesia; Department of Biology, Faculty of Medicine, Universitas Indonesia, Indonesia, Jl. Rawamangun Muka, Jakarta, 13220, Indonesia; Stem Cells and Tissue Engineering Research Center, IMERI, Faculty of Medicine, Universitas Indonesia, Indonesia; Department of Biology, Faculty of Mathematics and Natural Sciences, Mulawarman University, Samarinda, Indonesia |
Umiatin, Department of Physics, Faculty of Mathematics and Natural Science, Universitas Negeri Jakarta, Indonesia; Indrasari, W., Department of Physics, Faculty of Mathematics and Natural Science, Universitas Negeri Jakarta, Indonesia; Taryudi, Department of Electronic Engineering, Faculty of Engineering, Universitas Negeri Jakarta, Indonesia; Sari, P., Department of Biology, Faculty of Medicine, Universitas Indonesia, Indonesia, Jl. Rawamangun Muka, Jakarta, 13220, Indonesia; Mazfufah, N.F., Stem Cells and Tissue Engineering Research Center, IMERI, Faculty of Medicine, Universitas Indonesia, Indonesia; Rosadi, I., Department of Biology, Faculty of Mathematics and Natural Sciences, Mulawarman University, Samarinda, Indonesia |
Pulsed electromagnetic fields (PEMFs) have an important role in cell differentiation. Previous study reported that PEMFs had positive and negative effect towards cell differentiation that depends on their frequencies applied to the cells. Human adipose-derived stem cells (ASCs) are mesenchymal stem cells that have an ability to differentiate into several types of cell including adipocytes, chondrocytes and osteocytes. This study aimed to evaluate the effect of human ASCs towards their adipogenic differentiation during PEMFs exposure. Human ASCs were isolated from adipose tissue. The cells then cultured in specific medium of adipocyte that induced ASCs differentiation along with PEMFs exposure. The maximum magnetic field used is 2 mT with a frequency of 75 Hz. To confirm the effect of PEMFs exposure towards adipogenic differentiation, mRNA expression of lipo protein lipase (LPL) was measured in mRNA expression level. The results showed that ASCs cultured on adipogenic differentiation without PEMFs exposure gradually increased LPL expression until day 14 of observation, while ASCs with PEMFs exposure significantly decreased LPL expression from day 2 to day 14. Based on the results, we concluded that PEMFs exposure can inhibit LPL expression that suppressed adipogenic differentiation. © 2021 Institute of Physics Publishing. All rights reserved. |
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Electromagnetic field effects; Electromagnetic fields; Proteins; Stem cells; Adipogenic differentiations; Adipose derived stem cells; Cell differentiation; Cell-be; Cell/B.E; Electromagnetic field exposure; Human adipose; Lipo proteins; Mesenchymal stem cell; Pulsed electromagnetic fields; Cell culture |
IOP Publishing Ltd |
17426588 |
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Conference Paper |
Q4 |
210 |
18731 |
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119 |
Parikesit D., Adityagama M., Atmoko W., Birowo P., Taher A., Rasyid N. |
57163830300;57328473300;57193125664;6504153311;7005269743;56245069300; |
Reliability and validity of the Indonesian version of the aging males’ symptoms |
2021 |
Medical Journal of Indonesia |
30 |
3 |
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211 |
214 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118800087&doi=10.13181%2fmji.oa.215314&partnerID=40&md5=de2f7f19ff7768cc59e6ab7817803329 |
Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Urology, Faculty of Medicine, Universitas Indonesia, Universitas Indonesia Hospital, Depok, Indonesia |
Parikesit, D., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Department of Urology, Faculty of Medicine, Universitas Indonesia, Universitas Indonesia Hospital, Depok, Indonesia; Adityagama, M., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Atmoko, W., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Department of Urology, Faculty of Medicine, Universitas Indonesia, Universitas Indonesia Hospital, Depok, Indonesia; Birowo, P., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Taher, A., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rasyid, N., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
BACKGROUND Aging males’ symptoms (AMS) scale was developed to study the problems of aging males, especially related to the quality of life. Currently, there is no valid and reliable Indonesian version of the AMS scale. This study was aimed to translate and evaluate the validity and reliability of the Indonesian version of the AMS scale. METHODS This cross-sectional study translated the existing AMS scale into Indonesian, which was tested in 40 years old males from May to August 2020. Cross-cultural validation of the AMS scale was conducted by translating the questionnaire from English to Indonesian by two independent-certified translators. The validity of the Indonesian version of the AMS scale was measured by conducting a Pearson correlation (r) analysis. The reliability of this questionnaire was tested and retested in 118 participants with a 2-week interval. In addition, Cronbach’s alpha value was measured and used as a reference. The first test was conducted in a corporate blood donor event in Matraman, East Jakarta, and the retest was conducted in Cipto Mangunkusumo Hospital. RESULTS The Indonesian version of the AMS scale was valid and had a good internal consistency with a Cronbach’s alpha value of 0.74. The test-retest reliability showed good reliability with an r-value of 0.981. Pearson correlation test showed that all questions in the questionnaire were valid (p<0.05) and correlated positively. CONCLUSIONS The Indonesian version of the AMS scale derived from this study is valid and has good reliability. © 2021, Faculty of Medicine, Universitas Indonesia. All rights reserved. |
Aging males’ symptoms scale; Indonesian; Reliability and validity |
adult; aging; article; blood donor; Cronbach alpha coefficient; cross-sectional study; human; human experiment; internal consistency; language; major clinical study; male; questionnaire; test retest reliability; validity |
Faculty of Medicine, Universitas Indonesia |
08531773 |
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Article |
Q4 |
164 |
21905 |
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120 |
Soedarman S., Rahardjo H.E. |
57220581938;37762030000; |
Potential predictors of detrusor underactivity in a urology outpatient clinic: A 5-year single center experience study |
2021 |
Medical Journal of Indonesia |
30 |
3 |
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207 |
210 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118768336&doi=10.13181%2fmji.oa.215102&partnerID=40&md5=8286bb60fbc23a9907af0545c3ad23c0 |
Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Soedarman, S., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rahardjo, H.E., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
BACKGROUND Detrusor underactivity (DU) is diagnosed using urodynamics, which caused by a combination of strength and duration of the bladder muscle and resulted in prolonged bladder emptying. Invasive urodynamics, which are limited in many clinical settings, should be performed efficiently in high-risk patients to reduce the risk of emerging complications during and after the procedure. Therefore, this study was aimed to identify the potential predictors of DU for limited clinical settings. METHODS This retrospective study was retrieved from the medical records of patients who underwent urodynamics in the Department of Urology, Cipto Mangunkusumo Hospital from 2015 to 2020. Age, sex, bladder capacity, bladder compliance, bladder outlet obstruction, history of stroke, diabetes mellitus (DM) status, and neurological abnormalities were analyzed using chi-square and Mann–Whitney to examine the potential predictors of DU. The odds ratio (OR) of each factor was also calculated. Logistic regression was furtherly used for the analysis. RESULTS A total of 649 patients were included in this study. Male (OR = 1.74, 95% CI = 1.28–2.38) and DM patients (OR = 2.06, 95% CI = 1.36–3.11) had a higher risk of DU, while bladder outlet obstruction (OR = 0.54, 95% CI = 0.39–0.76) was the protective factor of DU. Furthermore, multivariate analysis showed that the potential predictors of DU were male (OR = 1.903, 95% CI = 1.37–2.64), DM (OR= 1.899, 95% CI = 1.22–2.95), and bladder outlet obstruction (OR = 0.32, 95% CI = 0.32–0.65). CONCLUSIONS Age, sex, bladder outlet obstruction, and history of DM could become the predictors of DU. © 2021, Faculty of Medicine, Universitas Indonesia. All rights reserved. |
Detrusor underactivity; Urinary bladder; Urodynamics |
adolescent; adult; age; aged; Article; bladder capacity; bladder compliance; bladder pressure; child; diabetes mellitus; diabetic patient; human; hypotonic bladder; major clinical study; male; neurologic disease; overactive bladder; sex; software; urodynamics |
Faculty of Medicine, Universitas Indonesia |
08531773 |
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Article |
Q4 |
164 |
21905 |
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121 |
Sutojo B., Irdam G.A. |
57218247988;57194729795; |
Safety of augmentation cystoplasty in patients with bladder abnormalities undergoing renal transplantation: A systematic review |
2021 |
Medical Journal of Indonesia |
30 |
3 |
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198 |
206 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118766468&doi=10.13181%2fmji.oa.204358&partnerID=40&md5=c0ca75b4e475d11f04014befaa03201a |
Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Sutojo, B., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Irdam, G.A., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
BACKGROUND Augmentation cystoplasty (AC) has been recently proposed to improve a bladder condition before or after a renal transplantation for an optimal allograft function. Until now, AC in adults with end-stage renal disease (ESRD) is uncommon and rarely practiced. This study aimed to investigate the safety of AC in patients with bladder abnormalities who required renal transplantation. METHODS Studies of patients with ESRD and abnormal bladder who underwent AC were searched in ProQuest, PubMed, EBSCO, and Cochrane Library online databases. Only studies published in English from January 1985 to May 2020 were included. The keywords used were renal transplantation, bladder dysfunction, cystoplasty, and their synonyms. Data were extracted by two independent authors who selected, screened, and assessed the articles’ eligibility and quality. The outcomes were graft survival rate and complications of AC. RESULTS A total of 19 articles were included. AC improved an intravesical pressure, a bladder capacity, and a compliance in patients with ESRD and bladder abnormalities, allowing patients to undergo the renal transplantation. Even though AC in patients with renal transplantation resulted in a significantly higher urinary tract infection rate than patients who underwent renal transplantation only, performing AC after renal transplantation was considered safe. CONCLUSIONS AC was considered safe for patients with bladder abnormalities who underwent renal transplantation. © 2021, Faculty of Medicine, Universitas Indonesia. All rights reserved. |
Cystoplasty; Efficacy; Renal transplantation; Safety |
Article; bladder pressure; bladder reconstruction; bladder rupture; colonoscopy; graft survival; kidney transplantation; nephrolithiasis; nonhuman; systematic review; ureter obstruction; urinary tract infection; urodynamics; urolithiasis; vesicoureteral reflux; wound healing |
Faculty of Medicine, Universitas Indonesia |
08531773 |
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Article |
Q4 |
164 |
21905 |
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145 |
Hansur L., Pawitan J.A. |
57296411600;6508348067; |
The potential of hydroxysafflor yellow a as an adjuvant in covid-19 patients with acute respiratory distress syndrome |
2021 |
International Medical Journal |
28 |
5 |
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527 |
531 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117118067&partnerID=40&md5=caa56a92d25ef57cc5e5c3533887adf1 |
Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Faculty of Medicine, Universitas Muhammadiyah Makassar, Makassar, Indonesia; Department of Histology, Faculty of Medicine, Universitas Indonesia, Indonesia; Stem Cell Medical Technology Integrated Service Unit, Dr. Cipto Mangunkusumo General Hospital/ Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Stem Cell and Tissue Engineering Research Center, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Hansur, L., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Faculty of Medicine, Universitas Muhammadiyah Makassar, Makassar, Indonesia; Pawitan, J.A., Department of Histology, Faculty of Medicine, Universitas Indonesia, Indonesia, Stem Cell Medical Technology Integrated Service Unit, Dr. Cipto Mangunkusumo General Hospital/ Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Stem Cell and Tissue Engineering Research Center, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Objective: To discuss the potential and molecular mechanism of Carthamus tincorius derived hydroxysafflor yellow A (HSYA) as an alternative herbal adjuvant that may regulate various signaling pathways that might be related to the regulatory effects in COVID-19 patients with ALI and ARDS. Methods: We search Web of Science, PubMed, and Scopus using keywords: Carthamus tinctorius, adjuvant, cytokine storm, COVID-19, SARS-Cov-2, acute lung injury (ALI), and Acute Respiratory Distress Syndrome (ARDS), on 11 September 2020, and 18 December 2020. Results and Discussions: In COVID-19 patients, SARS-CoV-2 replication might be associated with hyper induction of pro-in-flammatory cytokine, which is known as a cytokine storm, and may cause acute lung injury (ALI) that leads to Acute Respiratory Distress Syndrome (ARDS). Carthamus tincorius derived HSYA were used in many studies, in vivo in animal models or in vitro in cell lines and showed inhibition of multiple inflammatory pathways that were involved in ALI and ARDS, which might occur in covid-19 patients. HSYA showed pleiotropic effects in regulating cytokine levels. It regulated TNF-α, IL-1β, IL-6, IFN-β, and showed protective effect by blocking TLR4, MyD88, TRIF, IRF3, NF-κB to avoid cytokine storm and prevent tissue damage. HSYA was showed to reduce oxidative stress-mediated damage, and down-regulate inflammatory cytokines. Further, it was relatively safe when studied as an adjuvant in HIV and cancer patients. Conclusion: We supposed that HSYA could be used as an alternative adjuvant in COVID-19 patients with ARDS. However, clinical trials are needed to prove its efficacy in COVID-19 patients with ARDS. © 2021 Japan University of Health Sciences & Japan International Cultural Exchange Foundation. |
Carthamus tinctorius; COVID-19; Cytokine storm; HSYA; SARS-Cov-2 |
adjuvant; curcumin; hydroxysafflor yellow a; interleukin 1beta; interleukin 6; interleukin 8; myeloid differentiation factor 88; natural product; pathogen associated molecular pattern; toll like receptor 4; tumor necrosis factor; unclassified drug; acute lung injury; adult respiratory distress syndrome; antiinflammatory activity; apoptosis; Article; binding affinity; brain ischemia; cancer patient; coronavirus disease 2019; cytokine production; cytokine storm; down regulation; dyspnea; endothelial dysfunction; endothelium cell; enzyme activity; human; Human immunodeficiency virus; immune response; inflammation; lung edema; nonhuman; pleiotropy; protein expression; protein function; reperfusion injury; respiratory failure; Severe acute respiratory syndrome coronavirus 2; signal transduction |
Japan International Cultural Exchange Foundation |
13412051 |
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Article |
Q4 |
183 |
20490 |
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