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381 |
Chikih C., Suryokusumo G., Sulistomo A. |
57222637163;57205444996;57024018500; |
Effect of acute submaximal physical exercise before decompression dive on tumor necrosis factor alpha concentration among male trained divers |
2021 |
International Journal of Public Health Science |
10 |
2 |
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289 |
297 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103567616&doi=10.11591%2fijphs.v10i2.20666&partnerID=40&md5=8c8626032d01ce9797442118fb643071 |
Postgraduate Program Occupational Medicine, Faculty of Medicine, Universitas Indonesia, Indonesia; Klinik Hijau Putih 29, Primary Health Care Provider, Indonesia |
Chikih, C., Postgraduate Program Occupational Medicine, Faculty of Medicine, Universitas Indonesia, Indonesia, Klinik Hijau Putih 29, Primary Health Care Provider, Indonesia; Suryokusumo, G., Postgraduate Program Occupational Medicine, Faculty of Medicine, Universitas Indonesia, Indonesia; Sulistomo, A., Postgraduate Program Occupational Medicine, Faculty of Medicine, Universitas Indonesia, Indonesia |
The increase of inflammatory biomarkers due to decompression dive is one of the factors that could cause decompression sickness (DCS), one of them is tumor necrosis alpha (TNFα). According to the preconditioning theory, exercise before dive can reduce amount of gas bubble to prevent DCS. This study aimed to prove that exercise before diving can prevent increase of TNFα. This study employed quasi-experimental design with trained male divers. The subject divided into two groups, treatment and control. The treatment group got submaximal exercise with 70% heart rate intensity, using cycle ergometer with young men's Christian association (YMCA) procedure modify by Guritno, 24 hours before decompression dive 280 kPa bottom time 80 minute with US-NAVY table, whereas the control group only do decompression dive. TNFα expression was checked three times, at beginning of study, before dive and after dive. In treatment group there was insignificant decrease TNFα, from 7.06±1.85pg./ml to 6.75±1.81pg./ml, whereas the control group showed a significant increased TNFα, from 8.22 (1.45 to 13.11)pg./ml to 8.39 (1.73 to 12.18)pg/ml, and significant difference was found between the mean difference for two groups p<0.05. It can be concluded that acute submaximal exercise prevents an increase of TNFα after single dive decompression to prevent possibility occurring DCS). © 2021, Institute of Advanced Engineering and Science. All rights reserved. |
Decompression dive; Physical exercise; Preconditioning; Prevention of DCS; TNFα |
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Institute of Advanced Engineering and Science |
22528806 |
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Article |
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395 |
Dilogo I.H., Pawitan J.A., Tobing J.F.L., Fiolin J., Luviah E. |
56161962800;6508348067;36167767600;57194498274;56114966200; |
Amount of bone morphogenetic protein-2, epidermal growth factor, and vascular endothelial growth factor in adipose tissue, umbilical cord, and bone marrow mesenchymal stem cell derived secretome: An in-vitro study |
2021 |
Stem Cells in Disease Pathogenesis |
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187 |
206 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114959444&partnerID=40&md5=456465470c35e0929cc2d9166da2405e |
Department of Orthopaedic and Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Indonesia; Department of Histology, Faculty of Medicine Universitas Indonesia, Indonesia; Stem Cell and Tissue Engineering Research Center, Indonesian Medical Education and Research Institute (IMERI), Universitas Indonesia, Indonesia |
Dilogo, I.H., Department of Orthopaedic and Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Indonesia; Pawitan, J.A., Department of Histology, Faculty of Medicine Universitas Indonesia, Indonesia; Tobing, J.F.L., Department of Orthopaedic and Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Indonesia; Fiolin, J., Department of Orthopaedic and Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Indonesia; Luviah, E., Stem Cell and Tissue Engineering Research Center, Indonesian Medical Education and Research Institute (IMERI), Universitas Indonesia, Indonesia |
[No abstract available] |
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Nova Science Publishers, Inc. |
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9781536196580; 9781536196306 |
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Book Chapter |
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428 |
Soetisna T.W. |
57214887740; |
A new hope of cd133+ bone marrow stem cell for functional exercise capacity improvement in low ejection fraction coronary artery bypass graft patients: A clinical trial |
2021 |
Bali Medical Journal |
10 |
1 |
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229 |
233 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85106002523&doi=10.15562%2fbmj.v10i1.2255&partnerID=40&md5=80046a217774aa6ef82836d9a524c4ff |
Department of Cardiothoracic and Vascular Surgery, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Department of Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Soetisna, T.W., Department of Cardiothoracic and Vascular Surgery, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia, Department of Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Background: Patients with low ejection fraction who are undergoing coronary artery bypass graft (CABG) only have an insignificant improvement in ejection fraction. This condition will make a little hope to achieve an improvement in physical performance. But now, from a view study, CD133+ stem cells offer new hope for this situation. This study evaluates CD133+ bone marrow stem cells’ role for functional exercise capacity improvement in low ejection fraction coronary artery bypass graft patients. Methods: Thirty patients with ischemic heart disease who had ejection fraction<35% at the National Cardiovascular Center were randomized into 2 groups. The treatment group undergoes the CABG + CD133+ procedure and the control group undergoes the CABG only. All research subjects underwent follow-up before and 6 months after the procedure. Fraction ejection, scar size, wall motion score index, ventricular dimensions, myocardial perfusion measured by cardiac MRI, 6 Minutes Walking Test (6MWT) and Minnesota Living with Heart Failure Questionnaire (MLHFQ) as an additional parameter for physical performance and quality of life. Data was analyzed using SPSS version 21 for Windows. Results: The results of the fraction ejection parameters showed a significant improvement in the treatment group, from 25.88±5.66% to 34.57%±11.31% compared to CABG only 30.18±3.85% to 31.61±7.89% (p=0.040), in the perfusion defect showed improvement but not significant, left ventricular end-systolic volume and left ventricular end-diastolic volume showed improvement with no significant result, scar size was found to be an improvement in the treatment group 10 persons (76.92%) compared to the control group 5 persons (38, 46%) (p=0.040), the wall motion score index and 6MWT showed a significant improvement in the treatment group (p=0.003 and p=0.03, respectively). The MLHFQ parameter showed improvement but not significant. Conclusion: CD 133+ stem cell implantation in patients with low ejection fraction who undergo CABG provides improved myocardial function and indirectly improves functional exercise capacity and patients’ quality of life. © 2021, Sanglah General Hospital. All rights reserved. |
CABG; CD133+ Stem cell; Functional exercise capacity |
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Sanglah General Hospital |
20891180 |
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Article |
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429 |
Ocviyanti D., Putri R.A. |
57189661230;57226166006; |
Biopsychosocial aspect of pregnant women suspected brainstem death [Aspek Biopsikososial pada Perempuan Hamil dengan Kecurigaan Mati Batang Otak] |
2021 |
Indonesian Journal of Obstetrics and Gynecology |
9 |
2 |
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107 |
110 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115419653&doi=10.32771%2finajog.v9i2.1269&partnerID=40&md5=41a14ffbc68b4ced0cd44396ae92afad |
Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Ocviyanti, D., Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Putri, R.A., Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Objective: Diagnosis of brainstem death and the vital organ function support in the pregnant woman to prolong gestation to attain fetal viability is still controversial. The decision is influenced by ethical and legal issue in the country. Another consideration is the hospital cost and health insurance coverage. This article purpose is to report a case and discuss the biopsychosocial aspect of this issue, so the doctors know how to decide a similar case. Methods: We reported a suspected brainstem death in pregnant women and discussed the holistic approach. Case: This case is a-38-year-old women, third pregnancy, 22 weeks of gestation, referred from the secondary hospital in a comatose condition. She was diagnosed with brainstem dysfunction due to intracranial mass and cerebral oedema. She wasn't diagnosed with brainstem death due to the electrolyte imbalance that can cause this condition. We did the multidisciplinary management approach. We decided the termination of pregnancy would only be performed if the fetus reaches 28 weeks of gestational age (with survival rate on perinatology is 31%). From the husband point of view, since the attending doctors have not declared the mother to be dead, then the husband still want to keep the mother in full life support. The patient and the fetus died on the 8th day of hospitalization. The patient was fully paid for by Indonesian Health Insurance. Conclusions: Maternal brainstem dysfunction and brainstem death during pregnancy are rare. In Indonesia, ethical and legal consideration to keep both mother and fetus are appropriate with the general social, cultural, and religious values. However, we recommend managing every single case individually with an intensive multidisciplinary approach due to the possibility of the different personal value of the patient. © Creative Commons Atribuição-Não Comercial 4.0 Internacional |
Brain death; Brainstem dysfunction; Ethic; Fetal; Legal; Pregnancy |
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Indonesian Society of Obstetrics and Gynecology |
23386401 |
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Article |
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438 |
Hadi I.A.N., Ekaputri M., Baskoro J.C., Winarsih N.S. |
57345259600;57242005600;57242005500;57211183552; |
Association between duration of untreated psychosis and executive function in early-onset psychosis |
2021 |
Journal of Affective Disorders Reports |
4 |
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100068 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85125606448&doi=10.1016%2fj.jadr.2020.100068&partnerID=40&md5=fa88cf50f43a9cc6eaaa94d1676fa411 |
Medical Doctor Graduate, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Psychiatry Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hopsital, Jakarta, Indonesia |
Hadi, I.A.N., Medical Doctor Graduate, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Ekaputri, M., Medical Doctor Graduate, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Baskoro, J.C., Medical Doctor Graduate, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Winarsih, N.S., Department of Psychiatry Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hopsital, Jakarta, Indonesia |
Introduction: Psychosis is a severe mental illness that causes impaired executive function (EF). The prolonged duration of untreated psychosis (DUP) is one of the negative factors in the course of psychosis. However, the results of previous studies remain inconsistent. The aim of this study is to find out the association between DUP and all the components of EF, i.e. behavioral regulation and metacognition with all their subdomains. Method: This was a cross-sectional study involving patients with early onset-psychosis aged 5–18 years old. DUP were collected from medical records, whereas sociodemographic data were collected by interview and EF was measured using the Behavior Rating Inventory of Executive Function-Parent Indonesian Version questionnaire. Results: Total 50 subjects were included in the study. The median age of subjects was 15.9 ± 1.9 years old with schizophrenia as majority of diagnosis (58%). Median DUP was 2 (0; 84) months. Subjects were divided into short DUP (≤2 months) and long DUP (>2 months) group. A significant association was found between long DUP (>2 months) and higher Global Executive Composite (GEC) score indicating poorer function, which consisted of Behavioral Regulation Index (BRI) and Metacognition Index (MI) (p = 0.001, p = 0.007, p = 0.001, respectively). All subdomains of BRI and MI, except material organization, showed significant associations with DUP. Conclusion: There was a significant association between long DUP (>2 months) and poorer EF in early-onset psychosis. © 2021 The Author(s) |
Behavioral regulation; Duration of untreated psychosis; Early-onset psychosis; Executive function; Metacognition |
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Elsevier B.V. |
26669153 |
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451 |
Christian, Puruhita N., Himawan A., Muis S.F., Fasitasari M., Pangarsa E.A., Panigoro S.S., Sutandyo N. |
57224896360;57224902090;57224910728;57193264578;57192872474;57204907532;56790104300;26028099200; |
Fat intake in Javanese breast cancer patients: Any difference? |
2021 |
Bali Medical Journal |
10 |
1 |
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320 |
324 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85108565233&doi=10.15562%2fbmj.v10i1.2173&partnerID=40&md5=7840397cf684896b0d8d5929cbb1e87c |
Resident of Clinical Nutrition Department, Faculty of Medicine, Universitas Diponegoro, Dr. Kariadi Hospital, Semarang, Indonesia; Clinical Nutrition Department, Faculty of Medicine, Universitas Diponegoro, Dr. Kariadi Hospital, Semarang, Indonesia; Clinical Nutrition Department, SMC Telogorejo Hospital, Semarang, Indonesia; Faculty of Medicine, Universitas Islam Sultan Agung-Sultan Agung Islamic Hospital Semarang, Indonesia; Hematology-Oncology Division, Internal Medicine Department, Faculty of Medicine, Universitas Diponegoro, Dr. Kariadi Hospital, Semarang, Indonesia; Oncology Surgery Division, Surgery Department, Faculty of Medicine, Universitas Indonesia, Ciptomangunkusumo Hospital, Jakarta, Indonesia; Hematology-Oncology Division, Internal Medicine Department, Dharmais National Cancer Centre Hospital, Jakarta, Indonesia |
Christian, Resident of Clinical Nutrition Department, Faculty of Medicine, Universitas Diponegoro, Dr. Kariadi Hospital, Semarang, Indonesia; Puruhita, N., Clinical Nutrition Department, Faculty of Medicine, Universitas Diponegoro, Dr. Kariadi Hospital, Semarang, Indonesia, Clinical Nutrition Department, SMC Telogorejo Hospital, Semarang, Indonesia; Himawan, A., Clinical Nutrition Department, Faculty of Medicine, Universitas Diponegoro, Dr. Kariadi Hospital, Semarang, Indonesia, Clinical Nutrition Department, SMC Telogorejo Hospital, Semarang, Indonesia; Muis, S.F., Clinical Nutrition Department, Faculty of Medicine, Universitas Diponegoro, Dr. Kariadi Hospital, Semarang, Indonesia; Fasitasari, M., Clinical Nutrition Department, Faculty of Medicine, Universitas Diponegoro, Dr. Kariadi Hospital, Semarang, Indonesia, Faculty of Medicine, Universitas Islam Sultan Agung-Sultan Agung Islamic Hospital Semarang, Indonesia; Pangarsa, E.A., Hematology-Oncology Division, Internal Medicine Department, Faculty of Medicine, Universitas Diponegoro, Dr. Kariadi Hospital, Semarang, Indonesia; Panigoro, S.S., Oncology Surgery Division, Surgery Department, Faculty of Medicine, Universitas Indonesia, Ciptomangunkusumo Hospital, Jakarta, Indonesia; Sutandyo, N., Hematology-Oncology Division, Internal Medicine Department, Dharmais National Cancer Centre Hospital, Jakarta, Indonesia |
Background: Breast cancer is the second most prevalent women’s malignancy in Central Java. The risk of breast cancer incidence drops by 2.5 times for breast cancer if fat consumption is reduced by 50%, although not all types of fat intake increase the risk of breast cancer incidence. Fat consumption in Indonesia increased by 11% in the last 7 years. The study aims to analyze the differences in fat intake between breast cancer subjects and healthy subjects. Methods: This study is a cross-sectional study. We invited 45 outpatients diagnosed with breast cancer in Kariadi Hospital from January to August 2019 as well as 45 healthy subjects who are relatives or friends of the patients who met the inclusion criteria to participate in this study. Various types of fat intake were measured with quantitative food frequency questionnaires. The statistical analysis employed a chi-square test and Mann-Whitney test for non-parametric tests and an independent t-test for parametric data. Results: There was a significant difference in polyunsaturated fatty acid (PUFA) intake between breast cancer patients and healthy subjects (p=0.022). This study found no significant differences in total fat intake (p=0.677), saturated fatty acid (SFA) (p=0.368), monounsaturated fatty acid (MUFA) (p=0.593), omega 3 (p=0.095), omega 6 (p=0.092), and TFA (p=0.669) between breast cancer patients and healthy subjects. Conclusion: There is a significant difference in PUFA intake, but not in the other types of fat between breast cancer patients and healthy subjects. For further study, more precise and objective fat intake measurements may be achieved in studies with animal models. © 2021, Sanglah General Hospital. All rights reserved. |
Breast cancer; Fat; Intake; Nutrition |
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Sanglah General Hospital |
20891180 |
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Article |
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469 |
Surendra H., Elyazar I.R., Djaafara B.A., Ekawati L.L., Saraswati K., Adrian V., Widyastuti, Oktavia D., Salama N., Lina R.N., Andrianto A., Lestari K.D., Burhan E., Shankar A.H., Thwaites G., Baird J.K., Hamers R.L. |
57192694199;6506894785;57211600737;55600338600;57201491297;57221369753;57221446622;57219415909;57219411020;57221371068;57221369803;57221368778;36058554600;7005442634;6603796838;15921267800;23034345900; |
Clinical characteristics and mortality associated with COVID-19 in Jakarta, Indonesia: A hospital-based retrospective cohort study |
2021 |
The Lancet Regional Health - Western Pacific |
9 |
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100108 |
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11 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103798622&doi=10.1016%2fj.lanwpc.2021.100108&partnerID=40&md5=5627a271c3a8af3583dd02d7d63fadab |
Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia; Centre for Tropical Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia; Akademi Ilmuwan Muda Indonesia, Jakarta, Indonesia; MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Jakarta Provincial Health Office, Jakarta, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Viet Nam |
Surendra, H., Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia, Centre for Tropical Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia, Akademi Ilmuwan Muda Indonesia, Jakarta, Indonesia; Elyazar, I.R., Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia, Akademi Ilmuwan Muda Indonesia, Jakarta, Indonesia; Djaafara, B.A., Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia, MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom; Ekawati, L.L., Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Saraswati, K., Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Adrian, V., Jakarta Provincial Health Office, Jakarta, Indonesia; Widyastuti, Jakarta Provincial Health Office, Jakarta, Indonesia; Oktavia, D., Jakarta Provincial Health Office, Jakarta, Indonesia; Salama, N., Jakarta Provincial Health Office, Jakarta, Indonesia; Lina, R.N., Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia; Andrianto, A., Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia; Lestari, K.D., Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia; Burhan, E., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Shankar, A.H., Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Thwaites, G., Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom, Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Viet Nam; Baird, J.K., Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Hamers, R.L., Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Background: Data on COVID-19-related mortality and associated factors from low-resource settings are scarce. This study examined clinical characteristics and factors associated with in-hospital mortality of COVID-19 patients in Jakarta, Indonesia, from March 2 to July 31, 2020. Methods: This retrospective cohort included all hospitalised patients with PCR-confirmed COVID-19 in 55 hospitals. We extracted demographic and clinical data, including hospital outcomes (discharge or death). We used logistic regression to examine factors associated with mortality. Findings: Of 4265 patients with a definitive outcome by July 31, 3768 (88%) were discharged and 497 (12%) died. The median age was 46 years (IQR 32–57), 5% were children, and 31% had >1 comorbidity. Age-specific mortalities were 11% (7/61) for <5 years; 4% (1/23) for 5–9; 2% (3/133) for 10–19; 2% (8/638) for 20–29; 3% (26/755) for 30–39; 7% (61/819) for 40–49; 17% (155/941) for 50–59; 22% (132/611) for 60–69; and 34% (96/284) for ≥70. Risk of death was associated with higher age, male sex; pre-existing hypertension, diabetes, or chronic kidney disease; clinical diagnosis of pneumonia; multiple (>3) symptoms; immediate ICU admission, or intubation. Across all ages, risk of death was higher for patients with >1 comorbidity compared to those without; notably the risk was six-fold increased among patients <50 years (adjusted odds ratio 5.87, 95%CI 3.28–10.52; 27% vs 3% mortality). Interpretation: Overall in-hospital mortality was lower than reported in high-income countries, probably due to younger age distribution and fewer comorbidities. Deaths occurred across all ages, with >10% mortality among children <5 years and adults >50 years. © 2021 |
children; coronavirus; COVID-19; Indonesia; Mortality; SARS-CoV-2 |
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Elsevier Ltd |
26666065 |
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522 |
Purwati N.H., Rustina Y., Supriyatno B. |
57224632280;55387850300;37068046400; |
Knowledge and healthcare-seeking behavior of family caregivers of children with pneumonia: A qualitative study in an urban community in Indonesia |
2021 |
Belitung Nursing Journal |
7 |
2 |
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107 |
112 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85108107503&doi=10.33546%2fbnj.1268&partnerID=40&md5=a367278f4ff9f46d380f198e1e3929ee |
Faculty of Nursing, Universitas Muhammadiyah Jakarta, Jakarta, Indonesia; Faculty of Nursing, Universitas Indonesia, Jakarta, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Purwati, N.H., Faculty of Nursing, Universitas Muhammadiyah Jakarta, Jakarta, Indonesia; Rustina, Y., Faculty of Nursing, Universitas Indonesia, Jakarta, Indonesia; Supriyatno, B., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Background: Childhood pneumonia is the leading cause of death. Family caregivers may have a poor understanding of pneumonia, especially related to prevention and treatment. It is crucial to understand country-specific knowledge and healthcare-seeking behaviors of caregivers of children with pneumonia before planning programmatic responses, particularly in an urban community where the culture-social economic status is diverse. Objective: This study aimed to describe the knowledge and healthcare-seeking behavior of family caregivers of children with pneumonia in Indonesia's urban community. Methods: A descriptive qualitative study was conducted at a public hospital in Jakarta, Indonesia, from 10 December 2019 to 28 January 2020. Ten family caregivers of children with pneumonia were included, and a semi-structured interview was conducted for data collection. The audio recording was transcribed verbatim, and the data were analyzed using content analysis. Results: The emerged data indicated low knowledge of the family caregivers, especially mothers, which considered pneumonia a common cold only, and they failed to understand the risk of its transmission. Using traditional medicines was the first stage of healthcare-seeking behavior. If the symptoms worsened, the caregivers brought their children to the nearest health center. If there was no change in the symptoms, they headed to the hospital. The health center's location, condition, services, and staff attitude were considered factors to choose the services. Conclusion: Living in an urban area does not guarantee the family caregivers have better knowledge and good healthcare-seeking behavior. Therefore, nurses should provide comprehensive education about pneumonia, its symptoms, and treatment management to improve family care and prevent pneumonia-related deaths. Integrated management of children with illness is recommended to help the family caregivers of children with pneumonia receive treatment as quickly as possible. © The Author(s) 2021 |
Caregivers; Common cold; Healthcare-seeking behavior; Indonesia; Knowledge; Mothers; Nursing; Pneumonia |
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Belitung Raya Publisher - Belitung Raya Foundation |
24774073 |
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598 |
Lisnawati Y., Marianna Y., Rohsiswatmo R. |
57196459289;57267984800;55533574600; |
Increased levels of umbilical cord blood interleukin-6 (IL-6) and Serum C-Reactive Protein (CRP) in premature infants of Vitamin D deficient mothers [Peningkatan Kadar Interleukin-6 (IL-6) Darah Tali Pusat dan Serum C-Reactive Protein (CRP) pada Bayi Prematur Dari Ibu dengan Defisiensi Vitamin D] |
2021 |
Indonesian Journal of Obstetrics and Gynecology |
9 |
1 |
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21 |
25 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115413252&doi=10.32771%2finajog.v9i1.1397&partnerID=40&md5=15a9474083b536a9bdea004cadbfbb69 |
Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia Persahabatan Hospital; Department of Pediatric, Faculty of Medicine, Universitas Indonesia Dr., Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Lisnawati, Y., Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia Persahabatan Hospital; Marianna, Y., Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia Persahabatan Hospital; Rohsiswatmo, R., Department of Pediatric, Faculty of Medicine, Universitas Indonesia Dr., Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Objective: Increased levels of inflammatory factors in newborns are often associated with lower maternal vitamin D levels. This study aimed to find out the relationship between maternal and umbilical cord vitamin D serum levels on umbilical cord Interleukin-6 (IL-6) and serum C-Reactive Protein (CRP) levels in premature infants. Methods: The study was an observational analytic, cross-sectional design in mothers who underwent preterm birth at 28-34 weeks' gestation due to premature rupture of membranes (PROM) and their infants at Dr. Cipto Mangunkusumo General Hospital (RSCM), Jakarta and Persahabatan General Hospital, Jakarta, from January 2017 to August 2018. Levels of serum vitamin D of the maternal and umbilical cord, umbilical cord IL-6 and serum CRP in premature infants were recorded. Vitamin D level was divided into deficiency (<10 ng/mL), insufficiency (10-29 ng/mL), and normal (≥30 ng/mL) groups. The relationship of vitamin D levels with IL-6 and CRP was carried out using Kruskal Wallis test. Results: A total of 70 subjects met the research criteria. Umbilical cord IL-6 and serum CRP levels in premature infants of vitamin D deficient mothers were higher (20.31 pg/mL and 0.50 mg/L) compared to insufficient (3.34 pg/mL and 0.45 mg/L) and normal mothers (3.29 pg/mL and 0.30 mg/L), although not statistically significant (IL-6 p = 0.665, CRP p = 0.89). Referring to the umbilical cord blood vitamin D levels, the results were different and not as expected, in which the umbilical cord IL-6 and serum CRP levels of preterm infants in the deficiency (3.76 pg/mL and 0.35 mg/L) and insufficiency (3.37 pg/mL and 0.40 mg/L) groups were lower (IL-6) and not different (CRP) than the normal group (9.41 pg/mL and 0.40 mg/L). Conclusions: There were atendency for an increase in umbbilical cord IL-6 and serum CRP level in premature infants of Vitamin D deficient mother although these were not statistically significant. Based on the levels of vitamin D umbilical cord blood, the CRP levels in the serum of premature infants were not different, while the IL-6 levels in the deficiency and insufficiency group were lower than in the normal group. © Creative Commons Atribuição-Não Comercial 4.0 Internacional |
CRP; IL-6; Maternal Vitamin D; Umbilical cord Vitamin D |
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Indonesian Society of Obstetrics and Gynecology |
23386401 |
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Witjaksono J., Witjaksono F., Perdana A.A. |
6508217612;57070455800;57267346600; |
Role of lifestyle modification through dietary changes to endometrial receptivity on infertility women and obesity with polycystic ovary syndrome [Peran Perubahan Gaya Hidup melalui Perubahan Pola Diet terhadap Reseptivitas Endometrium Perempuan Infertil dan Obesitas dengan Sindrom Ovarium Polikistik] |
2021 |
Indonesian Journal of Obstetrics and Gynecology |
9 |
1 |
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49 |
54 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115407296&doi=10.32771%2finajog.v9i1.1415&partnerID=40&md5=e89d3e78b19a2a91949fb5c93e148d3b |
Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo General Hospital Indonesia, Jakarta, Indonesia; Department of Clinical Nutrition, Faculty of Medicine, Universitas Indonesia Dr. Cipto Mangunkusumo General Hospital Indonesia, Jakarta, Indonesia |
Witjaksono, J., Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo General Hospital Indonesia, Jakarta, Indonesia; Witjaksono, F., Department of Clinical Nutrition, Faculty of Medicine, Universitas Indonesia Dr. Cipto Mangunkusumo General Hospital Indonesia, Jakarta, Indonesia; Perdana, A.A., Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo General Hospital Indonesia, Jakarta, Indonesia |
Objective: To investigate the effect of lifestyle modification on endometrial receptivity of obese women with polycystic ovary syndrome using ultrasonography. Methods: This observational study was conducted at Dr. Cipto Mangunkusumo General Hospital Jakarta from August 2019 to May 2020. A total of 14 subjects were participated in this study. The subjects were advised to get nutrition counseling by nutritionist and then followed up the endometrial profiles for 6 months by ultrasonography. Results: A total 19 subjects were received nutrition counseling by Clinical nutritionist, but then, only 14 subjects were evaluated the endometrial study by Ultrasonography. There were several significant result between before and after treatment some subjects such as calories, body weight, body mass index, waist circumference (p<0.05) and type of the endometrial vascular zone, endometrium volume, and vascular flow index by ultrasonography (p<0.05). In this study, no significant results have been found on the correlation between dietary changes and changes in endometrial receptivity profiles. Conclusions: No significant correlation was observed between changes in anthropometrics and daily calorie intake with changes in endometrial vascular zones. © Indonesian Journal of Obstetrics and Gynecology 2021. |
Endometrial receptivity; Obese; Polycystic ovary syndrome; Ultrasonography |
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Indonesian Society of Obstetrics and Gynecology |
23386401 |
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