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Medical Journal of Indonesia(10)
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121	Sutojo B., Irdam G.A.	57218247988;57194729795;	Safety of augmentation cystoplasty in patients with bladder abnormalities undergoing renal transplantation: A systematic review	2021	Medical Journal of Indonesia	30	3	198	206		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118766468&doi=10.13181%2fmji.oa.204358&partnerID=40&md5=c0ca75b4e475d11f04014befaa03201a	Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Sutojo, B., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Irdam, G.A., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia	BACKGROUND Augmentation cystoplasty (AC) has been recently proposed to improve a bladder condition before or after a renal transplantation for an optimal allograft function. Until now, AC in adults with end-stage renal disease (ESRD) is uncommon and rarely practiced. This study aimed to investigate the safety of AC in patients with bladder abnormalities who required renal transplantation. METHODS Studies of patients with ESRD and abnormal bladder who underwent AC were searched in ProQuest, PubMed, EBSCO, and Cochrane Library online databases. Only studies published in English from January 1985 to May 2020 were included. The keywords used were renal transplantation, bladder dysfunction, cystoplasty, and their synonyms. Data were extracted by two independent authors who selected, screened, and assessed the articles’ eligibility and quality. The outcomes were graft survival rate and complications of AC. RESULTS A total of 19 articles were included. AC improved an intravesical pressure, a bladder capacity, and a compliance in patients with ESRD and bladder abnormalities, allowing patients to undergo the renal transplantation. Even though AC in patients with renal transplantation resulted in a significantly higher urinary tract infection rate than patients who underwent renal transplantation only, performing AC after renal transplantation was considered safe. CONCLUSIONS AC was considered safe for patients with bladder abnormalities who underwent renal transplantation. © 2021, Faculty of Medicine, Universitas Indonesia. All rights reserved.	Cystoplasty; Efficacy; Renal transplantation; Safety	Article; bladder pressure; bladder reconstruction; bladder rupture; colonoscopy; graft survival; kidney transplantation; nephrolithiasis; nonhuman; systematic review; ureter obstruction; urinary tract infection; urodynamics; urolithiasis; vesicoureteral reflux; wound healing	Faculty of Medicine, Universitas Indonesia	08531773	Article	Q4	164	21905	View
182	Wati N.S., Wongsasuluk P., Soewondo P.	57391635900;55760632100;23475336100;	A cross-sectional study on the telemedicine usage and glycemic status of diabetic patients during the COVID-19 pandemic	2021	Medical Journal of Indonesia	30	3	215	220		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85122007380&doi=10.13181%2fmji.oa.215558&partnerID=40&md5=2c18f04217c9ac4e93032fe573c7bff2	College of Public Health Sciences, Chulalongkorn University, Bangkok, Thailand; Metabolic, Cardiovascular and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia	Wati, N.S., College of Public Health Sciences, Chulalongkorn University, Bangkok, Thailand; Wongsasuluk, P., College of Public Health Sciences, Chulalongkorn University, Bangkok, Thailand; Soewondo, P., Metabolic, Cardiovascular and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia	BACKGROUND The coronavirus disease 2019 (COVID-19) pandemic disrupts self-management in diabetic patients in Indonesia. This study aimed to determine the telemedicine usage and factors contributing to glycemic control in type 2 diabetes mellitus (T2DM) patients during the pandemic. METHODS A cross-sectional study was conducted in T2DM patients aged 25–54 years. The questionnaire included general characteristics, diabetes conditions, consultation factors, and self-care management. Glycemic status was evaluated using glycated hemoglobin (HbA1c) levels, which was categorized into poor (HbA1c≥7%) and good glycemic control (HbA1c<7%). Data were analyzed using chi-square and binary logistic regression. RESULTS Of 264 patients, only 19.2% used telemedicine and 60.2% had poor glycemic control during the pandemic. Overweight or obesity (odds ratio [OR] = 5.740 [95% confidence interval [CI] = 2.554–12.899]; p<0.001), insulin injection (OR = 3.083 [95% CI = 1.238–7.677]; p = 0.016), and frequent fried food consumption (OR = 5.204 [95% CI = 1.631–16.606]; p = 0.005) were the factors contributing to poor glycemic control. The risk is lower if exercised regularly (OR = 0.036 [95% CI = 0.007–0.195]; p<0.001) and consulted with a doctor using telemedicine (OR = 0.193 [95% CI = 0.044–0.846]; p = 0.029) or in-person visits (OR = 0.065 [95% CI = 0.016–0.260]; p<0.001). CONCLUSIONS Glycemic control was not optimal during the COVID-19 pandemic. Therefore, keeping a healthy lifestyle and staying connected with a doctor are important to ensure optimal blood glucose control and reduce the risk of diabetes-related complications. © 2021 Authors.	COVID-19; Diabetes mellitus; Glycemic control; Indonesia; Telemedicine	hemoglobin A1c; insulin; adult; Article; blood glucose monitoring; body mass; consultation; coronavirus disease 2019; cross-sectional study; diabetes mellitus; diabetic patient; disease duration; education; employment status; exercise; female; food intake; glycemic control; human; income; Indonesia; major clinical study; marriage; mass communication; meal; medication compliance; non insulin dependent diabetes mellitus; obesity; pandemic; questionnaire; self care; smoking; telemedicine	Faculty of Medicine, Universitas Indonesia	08531773	Article	Q4	164	21905	View
188	Hamid A.R.A.H., Wangge G.	57202054669;36497482500;	The importance of evidence based education and policy in public health: Lessons learned from a repeated pandemic	2021	Medical Journal of Indonesia	30	3	175	176		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118807075&doi=10.13181%2fmji.ed.215821&partnerID=40&md5=9f5b4d7b96f6ec8842d115c438f55a1f	Medical Journal of Indonesia, Universitas Indonesia, Jakarta, Indonesia; Department of Urology, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Southeast Asian Ministers of Education-Regional Centre for Food and Nutrition (SEAMEO RECFON)/Pusat Kajian Gizi Regional Universitas Indonesia (PKGR UI), Jakarta, Indonesia	Hamid, A.R.A.H., Medical Journal of Indonesia, Universitas Indonesia, Jakarta, Indonesia, Department of Urology, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Wangge, G., Medical Journal of Indonesia, Universitas Indonesia, Jakarta, Indonesia, Southeast Asian Ministers of Education-Regional Centre for Food and Nutrition (SEAMEO RECFON)/Pusat Kajian Gizi Regional Universitas Indonesia (PKGR UI), Jakarta, Indonesia	[No abstract available]		coronavirus disease 2019; disease transmission; early diagnosis; Editorial; evidence based medicine; health care policy; human; Indonesia; medical education; medical research; nonhuman; pandemic; polymerase chain reaction; public health; Spanish influenza; vaccination	Faculty of Medicine, Universitas Indonesia	08531773	Editorial	Q4	164	21905	View
189	Louhenapessy N., Gantini R.S.E., Rahayu S., Lilipory E., Wibowo H., Soedarmono Y., Sutanto I.	57328098200;57328652300;57189095014;57328098300;57217690943;35729808300;6603791639;	Evaluating laboratory screening tests for malaria on blood donor candidates to reduce the risk of transfusion-transmitted malaria in an endemic area of indonesia	2021	Medical Journal of Indonesia	30	3	191	197		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118766270&doi=10.13181%2fmji.oa.215491&partnerID=40&md5=56dffb7462c5b89ab6601b6099db844e	Biomedical Science Institute, Transfusion Science Program, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Central Blood Transfusion Services, Jakarta, Indonesia; Blood Bank Technology, Indonesian Red Cross, Jakarta, Indonesia; Integrated Laboratory Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Provincial Health Office of Ambon City, Maluku, Indonesia; Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Directorate General of Health Care, Ministry of Health, Jakarta, Indonesia	Louhenapessy, N., Biomedical Science Institute, Transfusion Science Program, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Gantini, R.S.E., Biomedical Science Institute, Transfusion Science Program, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Central Blood Transfusion Services, Jakarta, Indonesia, Blood Bank Technology, Indonesian Red Cross, Jakarta, Indonesia; Rahayu, S., Integrated Laboratory Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Lilipory, E., Provincial Health Office of Ambon City, Maluku, Indonesia; Wibowo, H., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Soedarmono, Y., Directorate General of Health Care, Ministry of Health, Jakarta, Indonesia; Sutanto, I., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia	BACKGROUND Laboratory screening of blood donors for malaria has not been routinely performed in Indonesia. Current policy and practice simply exclude donors based on a history of active clinical malaria. This study was aimed to evaluate laboratory screening tests for malaria among blood donors in an endemic area of Indonesia. METHODS The study was conducted on 550 consecutive blood samples withdrawn from volunteer donors at the Red Cross Blood Transfusion Unit in Ambon city using microscopic and rapid diagnostic tests for antigen as well as for antibody. Furthermore, 248 of those 550 samples were also tested for the presence of malaria DNA using 18S rRNA marker. Statistical analysis was done descriptively using SPSS software version 15 (SPSS Inc., USA). RESULTS The overall malaria positivity rate among the donors was 4.5% (25/550). None of the specimens tested using microscopy or rapid test for malaria antigen assay were positive. However 22 (4.0%) samples were positive for malaria antibody against Plasmodium falciparum, while 3 (1.2%) were positive by PCR. CONCLUSIONS Laboratory testing for blood donors may be used to prevent transfusion-transmitted malaria in an endemic area of Indonesia. © 2021, Faculty of Medicine, Universitas Indonesia. All rights reserved.	Blood donors; Indonesia; Malaria	hemoglobin; immunoglobulin A antibody; immunoglobulin G antibody; immunoglobulin M antibody; RNA 18S; adolescent; adult; Article; blood donor; blood transmission; body weight; endemic disease; female; Giemsa stain; human; Indonesia; laboratory test; major clinical study; malaria; male; microscopy; nonhuman; Plasmodium falciparum; Plasmodium malariae; Plasmodium vivax; polymerase chain reaction; risk reduction; screening test	Faculty of Medicine, Universitas Indonesia	08531773	Article	Q4	164	21905	View
329	Ramlan A.A.W., Sugiharto A., Mutakim A.	57195941841;57226310870;57226313039;	Accuracy of pediatric advanced life support method for predicting the depth of endotracheal tube in indonesian children	2021	Medical Journal of Indonesia	30	2	123	128		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111164254&doi=10.13181%2fmji.oa.203835&partnerID=40&md5=a6c7bb086d05bdb4faba3e211bf246af	Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia	Ramlan, A.A.W., Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Sugiharto, A., Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Mutakim, A., Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia	BACKGROUND The pediatric advanced life support (PALS) method can predict the depth of endotracheal tube (ETT) in pediatric patients easily, but it has limitations due to variations in the children’s characteristics, especially the racial consideration. This study compared the accuracy of ETT depth prediction based on the PALS methods in Indonesian children. METHODS Patients aged 0–12 years, who underwent elective surgery with oral intubation, were recruited consecutively based on their ages: 0–24 months and 25 months–12 years for this cross-sectional study in Cipto Mangunkusumo Hospital, Jakarta, Indonesia from June to August 2014. Bland–Altman analysis was used to compare the two measurement methods: PALS method to predict the ETT depth accuracy and auscultation method to confirm the position of the ETT. Furthermore, correlation analysis was done to examine the relationship of age, weight, height, and ETT internal diameter with ETT depth. RESULTS 50 patients were recruited in each group. Bland–Altman test of ETT depth in the 0–24 months age group showed a 1.18 cm mean difference from confirmation using the auscultation method (limits of agreement −0.71 to 3.08). The 25 months–12 years age group showed a 1.11 cm mean difference with limits of agreement were −0.95 to 3.17 from confirmation using the auscultation method. Age and weight had the strongest correlation value to ETT depth in the 25 months–12 years age group (R2 = 62.3%). CONCLUSIONS The PALS method is inaccurate for predicting ETT depth in Indonesian children aged 0–12 years old compared with the auscultation method. © 2021 Authors.	Endotracheal tube; Pediatrics; Resuscitation	atracurium besilate; accuracy; age; Article; body height; body weight; child; correlation analysis; cross-sectional study; elective surgery; endotracheal intubation; endotracheal tube internal diameter; female; general anesthesia; human; Indonesian; lung auscultation; major clinical study; male; pediatric advanced life support; physical parameters; racism; school child; tracheostomy	Faculty of Medicine, Universitas Indonesia	08531773	Article	Q4	164	21905	View
330	Gondhowiardjo S., Hartanto S., Wirawan S., Jayalie V.F., Astiti I.A.P., Panigoro S.S., Sekarutami S.M., Rachman A., Bachtiar A.	6508327402;57217201121;57226152890;57195939736;57226145786;56790104300;56576294500;15056701600;56683183900;	Treatment delay of cancer patients in Indonesia: A reflection from a national referral hospital	2021	Medical Journal of Indonesia	30	2	129	137		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110729832&doi=10.13181%2fmji.oa.204296&partnerID=40&md5=0ead2a2c9a147a42c0b4b82c1186bd1e	Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Surgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Administration and Health Policy, Faculty of Public Health, Universitas Indonesia, Depok, Indonesia	Gondhowiardjo, S., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Hartanto, S., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Wirawan, S., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Jayalie, V.F., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Astiti, I.A.P., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Panigoro, S.S., Department of Surgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Sekarutami, S.M., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rachman, A., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Bachtiar, A., Department of Administration and Health Policy, Faculty of Public Health, Universitas Indonesia, Depok, Indonesia	BACKGROUND Cancer is a complex disease requiring a multidisciplinary approach in establishing prompt diagnosis and treatment. Treatment in a timely manner is crucial for the outcomes. Hence, this study aimed to provide information on treatment delay including patient and provider delays and its associated factors. METHODS Cancer patients were recruited conveniently in the outpatient clinic of Department of Radiation Oncology, Cipto Mangunkusumo Hospital, Indonesia between May and August 2015. All patients were asked to fill a questionnaire and interviewed in this cross-sectional study. Treatment delay was explored and categorized into patient delay and provider delay. Patient delay could be happened before (patient-delay-1) or after (patient-delay-2) the patient was diagnosed with cancer. Provider delay could be due to physician, system-diagnosis, and system-treatment delays. RESULTS Among 294 patients, 86% patient had treatment delay. Patient delay was observed in 153 patients, and 43% of them had a history of alternative treatment. An older age (p = 0.047), lower educational level (p = 0.047), and history of alternative treatment (p<0.001) were associated with patient delay. Meanwhile, 214 patients had provider delay, and 9%, 36%, and 80% of them experienced physician, system-diagnosis, and system-treatment delays, respectively. All types of provider delay were associated with patient delay (p<0.001). CONCLUSIONS Most of the patient had treatment delay caused by either patient or provider. © 2021 Authors.	Cancer; Indonesia; Treatment delay	adolescent; adult; aged; Article; breast cancer; cancer patient; cancer radiotherapy; cross-sectional study; educational status; female; human; Indonesia; major clinical study; male; nasopharynx cancer; outpatient department; patient referral; physiotherapy; prevalence; questionnaire; radiation oncology; risk factor; therapy delay; uterine cervix cancer	Faculty of Medicine, Universitas Indonesia	08531773	Article	Q4	164	21905	View
331	Irdam G.A., Febriyani, Rasyid N., Taher A.	57194729795;57226319849;56245069300;7005269743;	A systematic review of intracavernosal injection of mesenchymal stem cells for diabetic erectile dysfunction	2021	Medical Journal of Indonesia	30	2	96	105	1	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110674329&doi=10.13181%2fmji.oa.204475&partnerID=40&md5=41f468eff0f07099de19a39da32f2a41	Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Irdam, G.A., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Febriyani, Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rasyid, N., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Taher, A., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia	BACKGROUND As current erectile dysfunction (ED) treatments are limited, other treatment such as stem cells should be explored. Hence, this study aimed to review the sources, method of administration, and therapeutic effect of mesenchymal stem cells (MSCs) for diabetic ED treatment. METHODS All relevant articles regarding the use of MSCs for diabetic ED were searched in PubMed and Google Scholar databases from December 15, 2019 to January 1, 2020 published in the past 10 years. The keywords were “mesenchymal stem cells” and “diabetic ED”. The selection and critical appraisal of the studies were discussed. Diabetic ED was evaluated for functional and structural outcome. Functional outcome in animal studies was assessed by intracavernosal pressure/mean arterial pressure (ICP/ MAP) ratio, meanwhile the structural outcome was done microscopically. In human study, the assessments were done using international index of erectile function score (IIEF-5) to erection hardness score and penile Doppler ultrasonography. RESULTS There were 10 animal studies and 3 human studies. The studies used MSCs from adipose (n = 6), bone marrow (n = 4), placenta (n = 1), umbilical cord (n = 1), and muscle tissue (n = 1). The MSCs were administrated through intracavernosal injection in all studies. In all animal studies, functional outcome was improved, shown in higher ICP/MAP ratio. Microscopically, there were an increase of cavernosal endothelial cells, vascular endothelial growth factor, nitric oxide synthase, and smooth muscle cells. In human studies, IIEF-5 and erection hardness score were improved. Peak systolic velocity was also higher. CONCLUSIONS MSCs may be a promising therapy for diabetic ED; however, long-term safety concerns still need further investigations. © 2021, Faculty of Medicine, Universitas Indonesia. All rights reserved.	Diabetes mellitus; Erectile dysfunction; Mesenchymal stem cells	arterial pressure; Article; body mass; bone marrow; data extraction; DNA damage; Doppler ultrasonography; echography; erectile dysfunction; genomic instability; hardness; histochemistry; human; insulin sensitivity; International Index of Erectile Function; intracavernous pressure; mesenchymal stem cell; nonhuman; peak systolic velocity; placenta; questionnaire; shock wave therapy; smooth muscle cell; systematic review; umbilical cord	Faculty of Medicine, Universitas Indonesia	08531773	Article	Q4	164	21905	View
345	Parikesit D., Witjaksono F., Mochtar C.A., Rasyid N., Hamid A.R.A.H.	57163830300;57070455800;6506558321;56245069300;57202054669;	Impact of metabolic syndrome on lower urinary tract symptoms in patients with benign prostate hyperplasia	2021	Medical Journal of Indonesia	30	2	138	142		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110781511&doi=10.13181%2fmji.oa.214256&partnerID=40&md5=1ca9a518c25b6145dc4dc6f550d2833e	Urology Medical Staff Group, Universitas Indonesia Hospital, Universitas Indonesia, West Java, Depok, Indonesia; Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Parikesit, D., Urology Medical Staff Group, Universitas Indonesia Hospital, Universitas Indonesia, West Java, Depok, Indonesia; Witjaksono, F., Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Mochtar, C.A., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rasyid, N., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Hamid, A.R.A.H., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia	BACKGROUND Studies evaluating the relationship between metabolic syndrome (MetS) and lower urinary tract symptoms (LUTS) in men with benign prostate hyperplasia (BPH) are lacking in Indonesia. This study aimed to discover the association of LUTS and MetS in men with BPH. METHODS Subjects who underwent biopsy were recruited from Cipto Mangunkusumo Hospital, Jakarta, Indonesia from January 2014 to January 2018, but only men who had biopsy-proven BPH were included. Body mass index, waist circumference, fasting blood glucose, triglyceride, high-density lipoprotein, prostate volume (PV), and international prostate symptom score (IPSS) were collected before the biopsy. MetS criteria were based on the National Cholesterol Education Program Adult Treatment Panel III. IPSS was assessed for LUTS and consisted of irritative and obstructive symptoms and quality of life (QoL). Independent t-test or Mann–Whitney test was used to analyze numerical data. RESULTS Of 227 men with biopsy-proven BPH, 87 (38.3%) were diagnosed with MetS. PV was similar in men with or without MetS (54.4 [20.3–100] versus 49.9 [19.5–100] cm3, p = 0.239). Men with MetS generally had more LUTS (15 [1–30] versus 11 [0–35], p = 0.005), more irritative symptoms (8 [0–20] versus 6 [0–20], p = 0.007), and lower QoL (4 [0–6] versus 3 [0–6], p = 0.018). CONCLUSIONS BPH patients with MetS had greater LUTS, particularly irritative symptoms and QoL score. @ 2021 Authors.	Benign prostate hyperplasia; Lower urinary tract symptoms; Metabolic syndrome	high density lipoprotein cholesterol; triacylglycerol; Article; body mass; cross-sectional study; glucose blood level; human; human tissue; lower urinary tract symptom; major clinical study; male; metabolic syndrome X; prostate hypertrophy; prostate volume; quality of life; questionnaire; waist circumference	Faculty of Medicine, Universitas Indonesia	08531773	Article	Q4	164	21905	View
346	Irawati Y., Gondhowiardjo T.D., Soebono H.	57201260313;7801650709;6508242918;	Efficacy and safety of platinum chain and gold weight implants for paralytic lagophthalmos: A systematic review	2021	Medical Journal of Indonesia	30	2	106	115	1	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110572321&doi=10.13181%2fmji.oa.214683&partnerID=40&md5=1e4455ed4f7b0f8707adf603031b37e0	Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; JEC Eye Hospitals and Clinics, Jakarta, Indonesia; Department of Dermatovenereology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Dr. Sardjito Central General Hospital, Yogyakarta, Indonesia	Irawati, Y., Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia, JEC Eye Hospitals and Clinics, Jakarta, Indonesia; Gondhowiardjo, T.D., Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia, JEC Eye Hospitals and Clinics, Jakarta, Indonesia; Soebono, H., Department of Dermatovenereology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Dr. Sardjito Central General Hospital, Yogyakarta, Indonesia	BACKGROUND Surgery has been proposed as a treatment of paralytic lagophthalmos. However, no consensus has been reached on the best treatment. This study was aimed to investigate the efficacy and safety between platinum chain and gold weight implants to treat paralytic lagophthalmos. METHODS This study used all randomized controlled trials or observational studies (prospective or retrospective) using platinum chain and gold weight implants for paralytic lagophthalmos surgery that were published from 1990 to 2020 in the PubMed, Cochrane, and Google Scholar databases. Efficacy was indicated by the reduction of ≥3 in lagophthalmos, and safety was measured based on complications after surgery. RESULTS The efficacy of platinum chain and gold weight implants were 60–100% and 10–93.6%, respectively. The complications of platinum chain implant were 0–2.9% of extrusion and 0–3.3% of migration. However, gold weight implant had 0–13.3% of migration. CONCLUSIONS Both platinum chain and gold weight implants have similar efficacy to treat paralytic lagophthalmos. However, gold weight implant has a higher rate of complication. © 2021 Authors.	Paralytic lagophthalmus; Prostheses and implants; Surgical techniques	acoustic neuroma; Article; drug efficacy; drug safety; human; lagophthalmos; lid loading technique; paralytic lagophthalmos; systematic review; visual acuity	Faculty of Medicine, Universitas Indonesia	08531773	Article	Q4	164	21905	View
622	Budianto I.R., Firmansyah A., Moenadjat Y., Jusuf A.A., Soetikno V.	56072591000;57430911900;57190371576;57192275719;36769252100;	In vivo model of Hirschsprung-associated enterocolitis using benzalkonium chloride	2021	Medical Journal of Indonesia	30	4	239	244		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123725324&doi=10.13181%2fmji.oa.215339&partnerID=40&md5=0d7ad27ed35c326eece4ebc9bb2d637b	Biomedical Doctoral Program, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Surgery, School of Medicine and Health Sciences, Universitas Katolik Indonesia Atma Jaya, Jakarta, Indonesia; Department of Pediatric, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Histology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Pharmacology and Therapeutic, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia	Budianto, I.R., Biomedical Doctoral Program, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Surgery, School of Medicine and Health Sciences, Universitas Katolik Indonesia Atma Jaya, Jakarta, Indonesia; Firmansyah, A., Department of Pediatric, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Moenadjat, Y., Department of Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Jusuf, A.A., Department of Histology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Soetikno, V., Department of Pharmacology and Therapeutic, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia	BACKGROUND Hirschsprung-associated enterocolitis (HAEC) is a life-threatening complication of Hirschsprung’s disease. Studies using animal models on the pathogenesis of HAEC are limited. Thus, this study aimed to establish a rat model of HAEC using topical application of 0.1% benzalkonium chloride (BAC) in the sigmoid colon. METHODS 55 male Sprague Dawley rats aged 10−12 weeks old were separated into 11 groups. The control group (n = 5) was euthanized on day-7, and the other 10 groups (n = 5 in each group) treated with 0.1% BAC in the sigmoid colon for 15 min to induce Hirschsprung’s disease were euthanized on day-7,-10,-12,-14,-17,-19,-21,-23,-25, and-28. The sigmoid colon was excised, fixed in formalin, and sectioned for histological examinations with hematoxylin and eosin staining. The degree of HAEC was compared within all groups. RESULTS Rats that were sacrificed on day-7 to-12 showed the 1st degree or early HAEC, which was most likely caused by BAC application. The 2nd degree of HAEC occurred in rats that were sacrificed on day-14 that showed a macrophage infiltration in the sigmoid colon, thus fulfilled the initial criteria for HAEC (p = 0.0025 versus control). The degree of enterocolitis increased with time, and the highest degree was found in rats that were sacrificed on day-28 (p<0.001 versus control). CONCLUSIONS Topical application of 0.1% BAC for 15 min was successfully produced HAEC model in rats, which was occurred on day-14 after the application. This model provides a useful resource for further research on the pathogenesis of HAEC. © 2021 Authors.	Animal model; Colitis; Ganglions; Hirschsprung’s disease	benzalkonium chloride; eosin; hematoxylin; isoflurane; ketamine; xylazine; aganglionosis; animal model; animal tissue; anorexia; Article; autopsy; cell proliferation; cervical spine dislocation; controlled study; crypt cell; enterocolitis; Hirschsprung disease; in vivo study; laparotomy; macrophage; male; mucosa ulceration; necrosis; neutrophil chemotaxis; nonhuman; rat; sham procedure; sigmoid; Sprague Dawley rat; ulcer	Faculty of Medicine, Universitas Indonesia	08531773	Article	Q4	164	21905	View

Publikasi Scopus 926 artikel (Per 14 Maret 2022)