|
No records
|
|
190 |
Nugroho C.M.H., Silaen O.S.M., Kurnia R.S., Soejoedono R.D., Poetri O.N., Soebandrio A. |
57219405299;57219408428;57209271620;26424105300;45461221800;8602893200; |
Isolation and molecular characterization of the hemagglutinin gene of H9N2 avian influenza viruses from poultry in Java, Indonesia |
2021 |
Journal of Advanced Veterinary and Animal Research |
8 |
3 |
|
423 |
434 |
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117949519&doi=10.5455%2fjavar.2021.h530&partnerID=40&md5=4af241f49519b916f0bed70def7d2751 |
Doctoral Program Biomedical Science, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Animal Health Diagnostic Unit, PT Medika Satwa Laboratories, Bogor, Indonesia; Department of Animal Diseases and Public Health, Faculty of Veterinary Medicine, IPB University, Bogor, Indonesia; Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Department of Microbiology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia |
Nugroho, C.M.H., Doctoral Program Biomedical Science, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Silaen, O.S.M., Animal Health Diagnostic Unit, PT Medika Satwa Laboratories, Bogor, Indonesia; Kurnia, R.S., Doctoral Program Biomedical Science, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Soejoedono, R.D., Department of Animal Diseases and Public Health, Faculty of Veterinary Medicine, IPB University, Bogor, Indonesia; Poetri, O.N., Department of Animal Diseases and Public Health, Faculty of Veterinary Medicine, IPB University, Bogor, Indonesia; Soebandrio, A., Eijkman Institute for Molecular Biology, Jakarta, Indonesia, Department of Microbiology, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia |
Objective: The avian influenza virus (AIV) subtype H9N2 circulating in Indonesia has raised increasing concern about its impact on poultry and its public health risks. In this study, the H9N2 virus from chicken poultry farms in Java was isolated and characterized molecularly. Materials and Methods: Thirty-three pooled samples of chicken brain, cloacal swab, trachea, and oviduct were taken from multiple chickens infected with AIV in five regions of Java, Indonesia. The samples were isolated from specific pathogenic-free embryonated eggs that were 9 days old. Reverse transcription polymerase chain reaction and sequencing were used to identify H9N2 viruses. Results: This study was successful in detecting and characterizing 13 H9N2 isolates. The sequencing analysis of hemagglutinin genes revealed a 96.9%–98.8% similarity to the H9N2 AIV isolated from Vietnam in 2014 (A/muscovy duck/Vietnam/LBM719/2014). According to the phylogenetic analysis, all recent H9N2 viruses were members of the lineage Y280 and clade h9.4.2.5. Nine of the H9N2 isolates studied showed PSKSSR↓GLF motifs at the cleavage site, while four had PSKSSR↓GLF. Notably, all contemporary viruses have leucine (L) at position 216 in the receptor-binding region, indicating that the virus can interact with a human-like receptor. Conclusion: This study described the features of recent H9N2 viruses spreading in Java’s poultry industry. Additionally, H9N2 infection prevention and management must be implemented to avoid the occurrence of virus mutations in the Indonesian poultry industry. © 2021. The authors. Thisis an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0) |
Avian influenza; H9N2; HA gene; layer; phylogenetic analysis; sequencing |
|
Network for the Veterinarians of Bangladesh |
23117710 |
|
|
Article |
Q3 |
275 |
15692 |
|
|
|
204 |
Heltty H., Sitorus R., Martha E., Nusdwinuringtyas N. |
57262112500;57194329674;55841280100;56608215500; |
Experience of the patient's success in facing post-stroke urinary incontinence: The patient's perspective |
2021 |
Frontiers of Nursing |
8 |
3 |
|
291 |
301 |
|
1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115061619&doi=10.2478%2ffon-2021-0030&partnerID=40&md5=9c066e6d2b1fc65cd5adc1fc8034247d |
Faculty of Nursing, Medical Surgical, University of Indonesia, Jawa Barat, Depok, 16424, Indonesia; Faculty of Public Health, University of Indonesia, Jawa Barat, Depok, 16424, Indonesia; Faculty of Medicine, University of Indonesia, Jawa Barat, Depok, 16424, Indonesia |
Heltty, H., Faculty of Nursing, Medical Surgical, University of Indonesia, Jawa Barat, Depok, 16424, Indonesia; Sitorus, R., Faculty of Nursing, Medical Surgical, University of Indonesia, Jawa Barat, Depok, 16424, Indonesia; Martha, E., Faculty of Public Health, University of Indonesia, Jawa Barat, Depok, 16424, Indonesia; Nusdwinuringtyas, N., Faculty of Medicine, University of Indonesia, Jawa Barat, Depok, 16424, Indonesia |
Objective: Post-stroke urinary incontinence (UI) is one of the sequelae of stroke. This situation affects all aspects of the patient's life - physically, psychologically, socially, and spiritually. This study aimed to investigate the experience of patients' success in facing a post-stroke UI. Methods: A qualitative study using the Rapid Assessment Procedure (RAP) approach was used in this study. Informants were selected using purposive sampling. In-depth interviews with as many as 8 patients who had recovered from post-stroke UI and living in the greater area of Southeast Sulawesi (Indonesia) were conducted. In-depth interviews were also conducted with 8 caregivers and 2 nurses. Data were analyzed using a thematic analysis approach and interpretation of data was based on Humanbecoming theory and Self-care deficit theory of nursing. Results: Five successful things the patients experienced during post-stroke UI were identified. The five successes were as follows: they provided information to get to know and understand post-stroke UI, followed the procedures to overcome post-stroke UI, conducted self-control exercises and stayed motivated, performed daily activities independently according to ability, and made use of family support and peers' attention. Conclusions: These findings indicated that persistence, belief, independence, and social support (family and peer) made patients to successfully face their post-stroke UI and improved their quality of life. These findings also became the basis for developing a post-stroke UI management model based on Humanbecoming theory and Self-care deficit theory of nursing. © 2021 Heltty Heltty et al., published by Sciendo. |
experience of patient's success; patient's perspective; post-stroke urinary incontinence |
|
Sciendo |
25448994 |
|
|
Review |
Q4 |
152 |
22962 |
|
|
|
223 |
Razeghian E., Margiana R., Chupradit S., Bokov D.O., Abdelbasset W.K., Marofi F., Shariatzadeh S., Tosan F., Jarahian M. |
57223052224;56685900600;57211329338;56845561300;57208873763;57199650994;57225946579;57216155951;16241593900; |
Mesenchymal Stem/Stromal Cells as a Vehicle for Cytokine Delivery: An Emerging Approach for Tumor Immunotherapy |
2021 |
Frontiers in Medicine |
8 |
|
721174 |
|
|
|
2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114747651&doi=10.3389%2ffmed.2021.721174&partnerID=40&md5=eb488365f37edbafb0ec0a51d29dbfc9 |
Human Genetics Division, Medical Biotechnology Department, National Institute of Genetics Engineering and Biotechnology (NIGEB), Tehran, Iran; Department of Anatomy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Cipto Mangunkusumo Hospital, The National Referral Hospital, Central Jakarta, Indonesia; Master's Programme Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Occupational Therapy, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; Institute of Pharmacy, Sechenov First Moscow State Medical University, Moscow, Russian Federation; Laboratory of Food Chemistry, Federal Research Center of Nutrition, Biotechnology and Food Safety, Moscow, Russian Federation; Department of Health and Rehabilitation Sciences, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al Kharj, Saudi Arabia; Department of Physical Therapy, Kasr Al-Aini Hospital, Cairo University, Giza, Egypt; Immunology Research Center (IRC), Tabriz University of Medical Sciences, Tabriz, Iran; Department of Pharmacology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Student Research Committee, Semnan University of Medical Sciences, Semnan, Iran; Toxicology and Chemotherapy Unit (G401), German Cancer Research Center, Heidelberg, Germany |
Razeghian, E., Human Genetics Division, Medical Biotechnology Department, National Institute of Genetics Engineering and Biotechnology (NIGEB), Tehran, Iran; Margiana, R., Department of Anatomy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Cipto Mangunkusumo Hospital, The National Referral Hospital, Central Jakarta, Indonesia, Master's Programme Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Chupradit, S., Department of Occupational Therapy, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; Bokov, D.O., Institute of Pharmacy, Sechenov First Moscow State Medical University, Moscow, Russian Federation, Laboratory of Food Chemistry, Federal Research Center of Nutrition, Biotechnology and Food Safety, Moscow, Russian Federation; Abdelbasset, W.K., Department of Health and Rehabilitation Sciences, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University, Al Kharj, Saudi Arabia, Department of Physical Therapy, Kasr Al-Aini Hospital, Cairo University, Giza, Egypt; Marofi, F., Immunology Research Center (IRC), Tabriz University of Medical Sciences, Tabriz, Iran; Shariatzadeh, S., Department of Pharmacology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Tosan, F., Student Research Committee, Semnan University of Medical Sciences, Semnan, Iran; Jarahian, M., Toxicology and Chemotherapy Unit (G401), German Cancer Research Center, Heidelberg, Germany |
Pro-inflammatory cytokines can effectively be used for tumor immunotherapy, affecting every step of the tumor immunity cycle. Thereby, they can restore antigen priming, improve the effector immune cell frequencies in the tumor microenvironment (TME), and eventually strengthen their cytolytic function. A renewed interest in the anticancer competencies of cytokines has resulted in a substantial promotion in the number of trials to address the safety and efficacy of cytokine-based therapeutic options. However, low response rate along with the high toxicity associated with high-dose cytokine for reaching desired therapeutic outcomes negatively affect their clinical utility. Recently, mesenchymal stem/stromal cells (MSCs) due to their pronounced tropism to tumors and also lower immunogenicity have become a promising vehicle for cytokine delivery for human malignancies. MSC-based delivery of the cytokine can lead to the more effective immune cell-induced antitumor response and provide sustained release of target cytokines, as widely evidenced in a myriad of xenograft models. In the current review, we offer a summary of the novel trends in cytokine immunotherapy using MSCs as a potent and encouraging carrier for antitumor cytokines, focusing on the last two decades' animal reports. © Copyright © 2021 Razeghian, Margiana, Chupradit, Bokov, Abdelbasset, Marofi, Shariatzadeh, Tosan and Jarahian. |
cytokine; cytokine delivery; gene therapy; mesenchymal stem/stromal cells; tumor-immunotherapy |
|
Frontiers Media S.A. |
2296858X |
|
|
Review |
Q1 |
1388 |
2608 |
|
|
|
228 |
Reksodiputro M.H., Harahap A.R., Setiawan L., Yosia M. |
35090488800;6507325543;57053036100;57204933098; |
A Modified Preparation Method of Ideal Platelet-Rich Fibrin Matrix From Whole Blood |
2021 |
Frontiers in Medicine |
8 |
|
724488 |
|
|
|
1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114628863&doi=10.3389%2ffmed.2021.724488&partnerID=40&md5=2a784dc8d442d97efac9d34d1c6769cc |
Division of Facial Plastic & Reconstructive Surgery, Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Clinical Pathology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Clinical Pathology, Rumah Sakit Dharmais Pusat Kanker Nasional, Jakarta, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Reksodiputro, M.H., Division of Facial Plastic & Reconstructive Surgery, Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Harahap, A.R., Department of Clinical Pathology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Setiawan, L., Department of Clinical Pathology, Rumah Sakit Dharmais Pusat Kanker Nasional, Jakarta, Indonesia; Yosia, M., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
One bioproduct that is widely used in the wound healing process is platelet-rich plasma (PRP). PRP is a liquid solution with high autologous platelet concentration, making it a good source of growth factors to accelerate wound healing. Recent development in PRP had created a new product called platelet-rich fibrin matrix (PRFM), which has a denser and more flexible structure. PRFM is the newest generation of platelet concentrate with a fibrin matrix that holds platelet in it. The key concept in creating PRFM from PRP is the addition of CaCl2 followed by centrifugation, which converts fibrinogen to fibrin, and the fibrin cross-links to form a matrix that contains viable platelets. There are many commercially available kits to create PRFM, but they are often expensive and uneconomical. This research will test a modified method of making ideal PRFM from PRP without any commercial kits. The modified method will include determining the minimum level of CaCl2 used, the type of centrifuge, and the speed and duration of centrifugation. By performing a modified preparation method on five samples of whole blood, it was found that the ideal PRFM could be made by mixing PRP with 25 mM CaCl2 and centrifuging it at a speed of 2,264 × g for 25 min at room temperature. The PRP and PRFM platelet counts of this method tend to be lower than the platelet counts found in other studies. Although visually comparable, further study is needed to compare the performance of PRFMs made with this method and PRFMs made with commercial kits. © Copyright © 2021 Reksodiputro, Harahap, Setiawan and Yosia. |
CaCl2; centrifugation; fibrin matrix; platelet concentrate; platelet rich fibrin matrix; platelet rich plasma |
|
Frontiers Media S.A. |
2296858X |
|
|
Article |
Q1 |
1388 |
2608 |
|
|
|
236 |
Lancaster K.E., Mollan K.R., Hanscom B.S., Shook-Sa B.E., Ha T.V., Dumchev K., Djoerban Z., Rose S.M., Latkin C.A., Metzger D.S., Go V.F., Dvoriak S., Reifeis S.A., Piwowar-Manning E.M., Richardson P., Hudgens M.G., Hamilton E.L., Eshleman S.H., Susami H., Chu V.A., Djauzi S., Kiriazova T., Nhan D.T., Burns D.N., Miller W.C., Hoffman I.F. |
55503210000;26659057900;6603650318;55990940100;36988527800;8923601900;23472548200;12544917400;57235096800;35944632400;7102536801;57205192774;57193208279;35783326900;57203639655;6603567044;56450237600;7004740977;57202642757;57195576444;23495847800;55757875500;57317058700;7403171278;7406061778;7006682600; |
Engaging People Who Inject Drugs Living with HIV in Antiretroviral Treatment and Medication for Opioid Use Disorder: Extended Follow-up of HIV Prevention Trials Network (HPTN) 074 |
2021 |
Open Forum Infectious Diseases |
8 |
8 |
ofab281 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118242331&doi=10.1093%2fofid%2fofab281&partnerID=40&md5=6133eea6e10cff9e76240789c9b5b783 |
Division of Epidemiology, College of Public Health, Ohio State University, 1841 Neil Ave, 334 Cunz Hall, Columbus, OH 43210-1351, United States; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States; Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States; Statistical Center for HIV/AIDS Research and Prevention, Fred Hutchinson Cancer Research Center, Seattle, WA, United States; UNC Vietnam, Hanoi, Viet Nam; Ukrainian Institute on Public Health Policy, Kyiv, Ukraine; Faculty of Medicine, University of Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Science Facilitation Department, FHI 360, Durham, NC, United States; Department of Health Policy and Management, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, United States; HIV Prevention Research Division, Department of Psychiatry, School of Medicine, University of Pennsylvania, Philadelphia, PA, United States; Academy of Labor, Social Relations and Tourism, Kyiv, Ukraine; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, United States; Vietnam Administration of HIV/AIDS Control, Hanoi, Viet Nam; Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States; Division of Infectious Diseases, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States |
Lancaster, K.E., Division of Epidemiology, College of Public Health, Ohio State University, 1841 Neil Ave, 334 Cunz Hall, Columbus, OH 43210-1351, United States; Mollan, K.R., Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States; Hanscom, B.S., Statistical Center for HIV/AIDS Research and Prevention, Fred Hutchinson Cancer Research Center, Seattle, WA, United States; Shook-Sa, B.E., Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States; Ha, T.V., Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States, UNC Vietnam, Hanoi, Viet Nam; Dumchev, K., Ukrainian Institute on Public Health Policy, Kyiv, Ukraine; Djoerban, Z., Faculty of Medicine, University of Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rose, S.M., Science Facilitation Department, FHI 360, Durham, NC, United States; Latkin, C.A., Department of Health Policy and Management, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, United States; Metzger, D.S., HIV Prevention Research Division, Department of Psychiatry, School of Medicine, University of Pennsylvania, Philadelphia, PA, United States; Go, V.F., Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States; Dvoriak, S., Academy of Labor, Social Relations and Tourism, Kyiv, Ukraine; Reifeis, S.A., Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States; Piwowar-Manning, E.M., Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, United States; Richardson, P., Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, United States; Hudgens, M.G., Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States; Hamilton, E.L., Science Facilitation Department, FHI 360, Durham, NC, United States; Eshleman, S.H., Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, United States; Susami, H., Faculty of Medicine, University of Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Chu, V.A., UNC Vietnam, Hanoi, Viet Nam; Djauzi, S., Faculty of Medicine, University of Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Kiriazova, T., Ukrainian Institute on Public Health Policy, Kyiv, Ukraine; Nhan, D.T., Vietnam Administration of HIV/AIDS Control, Hanoi, Viet Nam; Burns, D.N., Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States; Miller, W.C., Division of Epidemiology, College of Public Health, Ohio State University, 1841 Neil Ave, 334 Cunz Hall, Columbus, OH 43210-1351, United States; Hoffman, I.F., Division of Infectious Diseases, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States |
Background: People who inject drugs (PWID) living with HIV experience inadequate access to antiretroviral treatment (ART) and medication for opioid use disorders (MOUD). HPTN 074 showed that an integrated intervention increased ART use and viral suppression over 52 weeks. To examine durability of ART, MOUD, and HIV viral suppression, participants could re-enroll for an extended follow-up period, during which standard-of-care (SOC) participants in need of support were offered the intervention. Methods: Participants were recruited from Ukraine, Indonesia and Vietnam and randomly allocated 3:1 to SOC or intervention. Eligibility criteria included: HIV-positive; active injection drug use; 18-60 years of age; ≥1 HIV-uninfected injection partner; and viral load ≥1,000 copies/mL. Re-enrollment was offered to all available intervention and SOC arm participants, and SOC participants in need of support (off-ART or off-MOUD) were offered the intervention. Results: The intervention continuation group re-enrolled 89 participants, and from week 52 to 104, viral suppression (<40 copies/mL) declined from 41% to 29% (estimated 9.4% decrease per year, 95% CI-17.0%;-1.8%). The in need of support group re-enrolled 94 participants and had increased ART (re-enrollment: 55%, week 26: 69%) and MOUD (re-enrollment: 16%, week 26: 25%) use, and viral suppression (re-enrollment: 40%, week 26: 49%). Conclusions: Viral suppression declined in year 2 for those who initially received the HPTN 074 intervention and improved maintenance support is warranted. Viral suppression and MOUD increased among in need participants who received intervention during the study extension. Continued efforts are needed for widespread implementation of this scalable, integrated intervention. © 2021 The Author(s). |
antiretroviral therapy; HIV infection; injection drug use; methadone/therapeutic use; viral load |
antiretrovirus agent; buprenorphine; methadone; adult; Article; CD4 lymphocyte count; Consolidated Standards of Reporting Trial; controlled study; disease transmission; epidemic; evaluation and follow up; female; health care quality; health education; hepatitis C; human; Human immunodeficiency virus infection; incidence; injection drug user; integrated health care system; intervention study; interview; major clinical study; male; medication compliance; medication for opioid use disorder; medication for opioid use disorder; middle aged; opiate addiction; outcome assessment; paramedical personnel; practice guideline; psychosocial development; randomized controlled trial; telephone interview; viral suppression; virus load; World Health Organization; young adult |
Oxford University Press |
23288957 |
|
|
Article |
Q1 |
1546 |
2161 |
|
|
|
394 |
Abdullah M., Sudrajat D.G., Muzellina V.N., Kurniawan J., Rizka A., Utari A.P., Pribadi R.R., Idrus M.F., Yusra Y., Meilany S., Surandy A., Shatri H., Rinaldi I., Pitoyo C.W., Renaldi K. |
7103393434;54893136100;57223968527;57193251655;57203243658;57113585900;57194732282;57223976376;57220998367;57193709281;57223964417;28767986500;23475122400;26022606900;57190963547; |
The value of anal swab RT-PCR for COVID-19 diagnosis in adult Indonesian patients |
2021 |
BMJ Open Gastroenterology |
8 |
1 |
e000590 |
|
|
|
3 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85106611204&doi=10.1136%2fbmjgast-2020-000590&partnerID=40&md5=cc17ce689ac73f1e46021151c9319871 |
Gastroenterology, Pancreatobilliary, and Endoscopy Division, Internal Medicine Department, Rumah Sakit Umum Pusat Nasional Dr Cipto Mangunkusumo, Central Jakarta, Special Capital Region of Jakarta, Indonesia; Indonesia Medical Education and Research Institute - Human Cancer Research Center, University of Indonesia Faculty of Medicine, Central Jakarta, Special Capital Region of Jakarta, Indonesia; Hepatobilliary Division, Internal Medicine Department, Rumah Sakit Umum Pusat Nasional Dr Cipto Mangunkusumo, Central Jakarta, Special Capital Region of Jakarta, Indonesia; Geriatric Division, Internal Medicine Department, Rumah Sakit Umum Pusat Nasional Dr Cipto Mangunkusumo, Central Jakarta, Special Capital Region of Jakarta, Indonesia; Department of Clinical Pathology, Rumah Sakit Umum Pusat Nasional Dr Cipto Mangunkusumo, Central Jakarta, Special Capital Region Jakarta, Indonesia; Research Center for Virology and Cancer Pathobiology, University of Indonesia Faculty of Medicine, Jakarta, Special Capital Region of Jakarta, Indonesia; Psychosomatic and Palliative Care Division, Internal Medicine Department, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Rumah Sakit Umum Pusat Nasional Dr Cipto Mangunkusumo, Special Capital Region of Jakarta, Central Jakarta, Indonesia; Hematology and Medical Oncology Division, Internal Medicine Department, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Rumah Sakit Umum Pusat Nasional Dr Cipto Mangunkusumo, Central Jakarta, Special Capital Region of Jakarta, Indonesia; Respirology and Critical Care Division, Internal Medicine Department, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Rumah Sakit Umum Pusat Nasional Dr Cipto Mangunkusumo, Central Jakarta, Special Capital Region of Jakarta, Indonesia |
Abdullah, M., Gastroenterology, Pancreatobilliary, and Endoscopy Division, Internal Medicine Department, Rumah Sakit Umum Pusat Nasional Dr Cipto Mangunkusumo, Central Jakarta, Special Capital Region of Jakarta, Indonesia, Indonesia Medical Education and Research Institute - Human Cancer Research Center, University of Indonesia Faculty of Medicine, Central Jakarta, Special Capital Region of Jakarta, Indonesia; Sudrajat, D.G., Gastroenterology, Pancreatobilliary, and Endoscopy Division, Internal Medicine Department, Rumah Sakit Umum Pusat Nasional Dr Cipto Mangunkusumo, Central Jakarta, Special Capital Region of Jakarta, Indonesia; Muzellina, V.N., Gastroenterology, Pancreatobilliary, and Endoscopy Division, Internal Medicine Department, Rumah Sakit Umum Pusat Nasional Dr Cipto Mangunkusumo, Central Jakarta, Special Capital Region of Jakarta, Indonesia; Kurniawan, J., Hepatobilliary Division, Internal Medicine Department, Rumah Sakit Umum Pusat Nasional Dr Cipto Mangunkusumo, Central Jakarta, Special Capital Region of Jakarta, Indonesia; Rizka, A., Geriatric Division, Internal Medicine Department, Rumah Sakit Umum Pusat Nasional Dr Cipto Mangunkusumo, Central Jakarta, Special Capital Region of Jakarta, Indonesia; Utari, A.P., Gastroenterology, Pancreatobilliary, and Endoscopy Division, Internal Medicine Department, Rumah Sakit Umum Pusat Nasional Dr Cipto Mangunkusumo, Central Jakarta, Special Capital Region of Jakarta, Indonesia; Pribadi, R.R., Gastroenterology, Pancreatobilliary, and Endoscopy Division, Internal Medicine Department, Rumah Sakit Umum Pusat Nasional Dr Cipto Mangunkusumo, Central Jakarta, Special Capital Region of Jakarta, Indonesia; Idrus, M.F., Gastroenterology, Pancreatobilliary, and Endoscopy Division, Internal Medicine Department, Rumah Sakit Umum Pusat Nasional Dr Cipto Mangunkusumo, Central Jakarta, Special Capital Region of Jakarta, Indonesia; Yusra, Y., Department of Clinical Pathology, Rumah Sakit Umum Pusat Nasional Dr Cipto Mangunkusumo, Central Jakarta, Special Capital Region Jakarta, Indonesia; Meilany, S., Research Center for Virology and Cancer Pathobiology, University of Indonesia Faculty of Medicine, Jakarta, Special Capital Region of Jakarta, Indonesia; Surandy, A., Gastroenterology, Pancreatobilliary, and Endoscopy Division, Internal Medicine Department, Rumah Sakit Umum Pusat Nasional Dr Cipto Mangunkusumo, Central Jakarta, Special Capital Region of Jakarta, Indonesia; Shatri, H., Psychosomatic and Palliative Care Division, Internal Medicine Department, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Rumah Sakit Umum Pusat Nasional Dr Cipto Mangunkusumo, Special Capital Region of Jakarta, Central Jakarta, Indonesia; Rinaldi, I., Hematology and Medical Oncology Division, Internal Medicine Department, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Rumah Sakit Umum Pusat Nasional Dr Cipto Mangunkusumo, Central Jakarta, Special Capital Region of Jakarta, Indonesia; Pitoyo, C.W., Respirology and Critical Care Division, Internal Medicine Department, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Rumah Sakit Umum Pusat Nasional Dr Cipto Mangunkusumo, Central Jakarta, Special Capital Region of Jakarta, Indonesia; Renaldi, K., Gastroenterology, Pancreatobilliary, and Endoscopy Division, Internal Medicine Department, Rumah Sakit Umum Pusat Nasional Dr Cipto Mangunkusumo, Central Jakarta, Special Capital Region of Jakarta, Indonesia |
Objective This study will test the performance of the anal swab PCR test when compared with the nasopharyngeal swab PCR test as a diagnostic tool for COVID-19. Design An observational descriptive study which included hospitalised suspected, or probable cases of hopitalised COVID-19 patients, conducted in Dr. Cipto Mangunkusumo National Hospital, Ciputra Hospital, Mitra Keluarga Depok Hospital and Mitra Keluarga Kelapa Gading Hospital, Indonesia. Epidemiological, clinical, laboratory and radiology data were obtained. Nasopharyngeal and anal swabs specimens were collected for SARS-CoV-2 RNA detection. Results We analysed 136 subjects as part of this study. The clinical spectrum of COVID-19 manifesation in this study was typical of hospitalised patients, with 25% classified as mild cases, 14.7% in severe condition and 12.5% of subjects classified as having acute respiratory distress syndrome. When compared with nasopharyngeal swab as the standard specimen for reverse transcription polymerase chain reaction (RT-PCR) detection of SARS-CoV-2 antigen, the sensitivity and specificity of the anal swab was 36.7% and 93.8%, respectively. The positive and negative predictive value were 97.8% and 16.5 %, respectively. The performance of the anal swab remained similar when only the subgroup of patients with gastrointestinal symptoms (n=92, 67.6%) was analysed (sensitivity 40% and specificity 91.7%). Out of all the subjects included in analysis, 67.6% had gastrointestinal symptoms. Similarly, 73.3% of patients in the anal swab-positive group had gastrointestinal symptoms. The two most common gastrointestinal symptoms in the subjects' population were nausea and anorexia. Conclusion Anal swab specimen has low sensitivity (36.7%) but high specificity (93.8%) for detecting SARS-CoV-2 antigen by RT-PCR. Only one additional positive result was found by anal swab among the nasopharyngeal swab-negative group. Anal swab may not be needed as an additional test at the beginning of a patient's diagnostic investigation and nasopharyngeal swab RT-PCR remains as the standard diagnostic test for COVID-19. © 2020 American Society of Mechanical Engineers (ASME). All rights reserved. |
anal; COVID-19; diagnostic virology |
abdominal pain; adult; adult respiratory distress syndrome; anal swab; anorexia; Article; body mass; clinical laboratory; controlled study; coronavirus disease 2019; coughing; COVID-19 testing; current smoker; diagnostic test accuracy study; diarrhea; ex-smoker; female; fever; gastrointestinal symptom; headache; heart disease; hospital patient; human; hypertension; Indonesian; lung disease; major clinical study; malaise; male; mortality rate; nasopharyngeal swab; nausea; non insulin dependent diabetes mellitus; practice guideline; predictive value; priority journal; respiratory tract infection; reverse transcription polymerase chain reaction; sensitivity and specificity; sore throat |
BMJ Publishing Group |
20544774 |
|
|
Article |
Q1 |
1240 |
3126 |
|
|
|
427 |
Setiati S., Soejono C.H., Harimurti K., Dwimartutie N., Aryana I.G.P.S., Sunarti S., Budiningsih F., Mulyana R., Dwipa L., Sudarso A., Rensa R., Istanti R., Azwar M.K., Marsigit J. |
14325991900;24472241900;23473513200;37067234900;37062993600;57215563311;56483278600;57203246879;55321762700;57223602321;6504343309;23496653300;57202798959;57218912589; |
Frailty and Its Associated Risk Factors: First Phase Analysis of Multicentre Indonesia Longitudinal Aging Study |
2021 |
Frontiers in Medicine |
8 |
|
658580 |
|
|
|
2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105939470&doi=10.3389%2ffmed.2021.658580&partnerID=40&md5=b2d32afefa94ab6754eec53482b82d31 |
Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Clinical Epidemiology and Evidence-Based Medicine Unit, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Udayana, Bali, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Sebelas Maret, Solo, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Andalas, Padang, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Padjajaran, Bandung, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Hasanuddin, Makasar, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Atma Jaya, Jakarta, Indonesia |
Setiati, S., Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia, Clinical Epidemiology and Evidence-Based Medicine Unit, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Soejono, C.H., Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Harimurti, K., Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia, Clinical Epidemiology and Evidence-Based Medicine Unit, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Dwimartutie, N., Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Aryana, I.G.P.S., Department of Internal Medicine, Faculty of Medicine, Universitas Udayana, Bali, Indonesia; Sunarti, S., Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia; Budiningsih, F., Department of Internal Medicine, Faculty of Medicine, Universitas Sebelas Maret, Solo, Indonesia; Mulyana, R., Department of Internal Medicine, Faculty of Medicine, Universitas Andalas, Padang, Indonesia; Dwipa, L., Department of Internal Medicine, Faculty of Medicine, Universitas Padjajaran, Bandung, Indonesia; Sudarso, A., Department of Internal Medicine, Faculty of Medicine, Universitas Hasanuddin, Makasar, Indonesia; Rensa, R., Department of Internal Medicine, Faculty of Medicine, Universitas Atma Jaya, Jakarta, Indonesia; Istanti, R., Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Azwar, M.K., Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Marsigit, J., Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia |
Background: National long-term care development requires updated epidemiological data related to frailty. We aimed to find the prevalence of frailty and its associated factors among Indonesian elderly. Methods: We conducted first-phase cross-sectional analysis of Indonesia Longitudinal Aging Study (INALAS) data collected from community-dwelling outpatients aged 60 years and older without acute illness in nine geriatric service care centres. Descriptive, bivariate and multivariate analyses were conducted. Results: Among 908 elderly in this study, 15.10% were robust, 66.20% were pre-frail, and 18.70% were frail. Functional dependence was associated with frailty among Indonesian elderly (OR 5.97, 95% CI 4.04–8.80). Being depressed and at risk for malnutrition were also associated with frailty with OR 2.54, 95% CI 1.56–4.12, and OR 2.56, 95% CI 1.68–3.90, respectively. Prior history of fall (OR 1.77, 95% CI 1.16–2.72) and hospitalization (OR 1.46, 95% CI 0.97–2.20) in the previous 12 months were associated with frailty. There is also significant association between poly pharmacy and frailty (OR 2.42, 95% CI 1.50–3.91). Conclusion: Approximately one in five Indonesian community-dwelling elderly was frail. Frailty is associated with functional dependence, being at risk for malnutrition or being malnourished, depression, history of fall, history of hospitalization, and poly pharmacy. There may be bidirectional relationships between the risk factors and frailty. The development of long-term care in Indonesia should be considered, without forcing the elderly who need it. © Copyright © 2021 Setiati, Soejono, Harimurti, Dwimartutie, Aryana, Sunarti, Budiningsih, Mulyana, Dwipa, Sudarso, Rensa, Istanti, Azwar and Marsigit. |
community-dwelling elderly; frailty; Indonesia; long-term care; prevalence; risk factors |
adult; aged; aging; Article; community dwelling person; cross-sectional study; depression; falling; female; frailty; functional status; high risk population; hospitalization; human; Indonesian; longitudinal study; major clinical study; male; malnutrition; medical history; outpatient; polypharmacy; prevalence; risk factor |
Frontiers Media S.A. |
2296858X |
|
|
Article |
Q1 |
1388 |
2608 |
|
|
|
808 |
Ambarsari C.G., Hidayati E.L., Tridjaja B., Mochtar C.A., Wulandari H.F., Harahap A.S., Grace A. |
57211850895;57200542624;6504507193;6506558321;57223434925;57218511857;57217085273; |
Silent Hypertensive Crisis in an Adolescent: First Case Report of Pediatric Pheochromocytoma from Indonesia |
2021 |
Global Pediatric Health |
8 |
|
|
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105884851&doi=10.1177%2f2333794X211015484&partnerID=40&md5=51b6ae929a36713aa5a073baeb034198 |
Faculty of Medicine, Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Ambarsari, C.G., Faculty of Medicine, Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Hidayati, E.L., Faculty of Medicine, Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Tridjaja, B., Faculty of Medicine, Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Mochtar, C.A., Faculty of Medicine, Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Wulandari, H.F., Faculty of Medicine, Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Harahap, A.S., Faculty of Medicine, Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Grace, A., Faculty of Medicine, Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Secondary hypertension in children, to the rare extent, can be caused by endocrine factors such as pheochromocytoma, an adrenal tumor that secretes catecholamine. Only a few cases have been reported in the past 3 decades. To the best of our knowledge, this is the first case report of pediatric pheochromocytoma from Indonesia. We reviewed a case of a 16-year-old Indonesian boy with history of silent hypertensive crisis who was referred from a remote area in an island to the pediatric nephrology clinic at Cipto Mangunkusumo Hospital, Jakarta, Indonesia. Despite medications, his symptoms persisted for 14 months. At the pediatric nephrology clinic, pheochromocytoma was suspected due to symptoms of catecholamine secretion presented, which was palpitation, diaphoresis, and weight loss. However, as the urine catecholamine test was unavailable in Indonesia, the urine sample was sent to a laboratory outside the country. The elevated level of urine metanephrine, focal pathological uptake in the right adrenal mass seen on 131I-MIBG, and histopathology examination confirmed the suspicion of pheochromocytoma. Following the tumor resection, he has been living with normal blood pressure without antihypertensive medications. This case highlights that pheochromocytoma should always be included in the differential diagnoses of any atypical presentation of hypertension. In limited resources setting, high clinical awareness of pheochromocytoma is required to facilitate prompt referral. Suspicion of pheochromocytoma should be followed by measurement of urine metanephrine levels. Early diagnosis of pheochromocytoma would fasten the optimal cure, alleviate the symptoms of catecholamine release, and reverse hypertension. © The Author(s) 2021. |
adrenal glands; blood pressure; epinephrine; metanephrine; MIBG; norepinephrine |
bisoprolol; captopril; catecholamine; creatinine; furosemide; liothyronine; nebivolol; nifedipine; telmisartan; terazosin; vitamin D; adolescent; adrenalectomy; Article; case report; clinical article; diaphoresis; Doppler flowmetry; free thyroxine index; heart palpitation; human; hypertension; hypertensive crisis; Indonesian; kidney artery stenosis; male; nuclear magnetic resonance imaging; pheochromocytoma; scintigraphy; tachycardia |
SAGE Publications Inc. |
2333794X |
|
|
Article |
Q2 |
354 |
13264 |
|
|
|
840 |
Sihombing A.T., Taher A., Rodjani A., Mochtar C.A., Hakim L., Daryanto B., Danarto H.R., Umbas R. |
57218510635;7005269743;6504653529;6506558321;57200406177;57208512904;57222667970;6602634832; |
Assessing the online objective structured clinical examinations in urology qualifying exam for urology residents in Indonesia during COVID-19 time |
2021 |
MethodsX |
8 |
|
101316 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103707591&doi=10.1016%2fj.mex.2021.101316&partnerID=40&md5=493809572dae72b1fbf5b2b8e4d8bf25 |
Department of Urology, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia; Department of Urology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Urology, Faculty of Medicine, Airlangga University, Surabaya, Indonesia; Department of Urology, Faculty of Medicine, Brawijaya University, Malang, Indonesia; Department of Urology, Faculty of Medicine, Gadjah Mada University, Yogyakarta, Indonesia |
Sihombing, A.T., Department of Urology, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia; Taher, A., Department of Urology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Rodjani, A., Department of Urology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Mochtar, C.A., Department of Urology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Hakim, L., Department of Urology, Faculty of Medicine, Airlangga University, Surabaya, Indonesia; Daryanto, B., Department of Urology, Faculty of Medicine, Brawijaya University, Malang, Indonesia; Danarto, H.R., Department of Urology, Faculty of Medicine, Gadjah Mada University, Yogyakarta, Indonesia; Umbas, R., Department of Urology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
This project aimed to assess the Online National Board of Urology Objective Structured Clinical Examination (OSCE) feasibility in evaluating candidates simultaneously from five urology training centers in Indonesia during the COVID-19 pandemic. Data were collected from two online OSCE simulation trials and the Online National Board of Urology OSCE. A self-administered questionnaire was used to assess examiners and candidates’ perception. The average final score of the Online OSCE was compared to previous face-to-face OSCE results. All candidates and examiners (100%) heard and saw clearly the audio-visual in both OSCE simulation trials. None of the candidates had a failing score on the mock exam from all stations. There was a statistically significant difference between the online OSCE and December 2019 face-to-face OSCE. The Online National Board Urology OSCE was feasible and comparable to face-to-face OSCE in evaluating urology candidates. It may be beneficial for the future OSCE method in the medical education system. • Objective Structured Clinical Examination (OSCE) which assesses a broad range of urology candidates’ high-level clinical skills, is a more valid and reliable assessment instrument than the traditional oral examination • The Online National Board of Urology OSCE method can help evaluate urology candidates, especially during the unprecedented COVID-19 pandemic © 2021 |
COVID-19 Pandemic; Online Examination; Online National Board Examination; Online National Board of Urology Objective Structured Clinical Examination (OSCE); OSCE method; Urology Examination |
academic failure; Article; audiovisual aid; clinical examination; coronavirus disease 2019; e-learning; feasibility study; human; Indonesia; medical education; objective structured clinical examination; pandemic; priority journal; resident; simulation; urology |
Elsevier B.V. |
22150161 |
|
|
Article |
Q2 |
356 |
13209 |
|
|
|
870 |
Prasetyo M., Rahardja R.R., Yanuar A., Prihartono J., Setiawan S.I. |
57192905252;57222100194;57222087272;6602605635;57195939543; |
Ultrasonography evaluation of the normal ulnar nerve in adult: Comparison of the cross-sectional area at elbow extension and flexion |
2021 |
European Journal of Radiology Open |
8 |
|
100331 |
|
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101370509&doi=10.1016%2fj.ejro.2021.100331&partnerID=40&md5=f9e415e711bd67bbe8b7b71cf1b20376 |
Department of Radiology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Department of Neurology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Prasetyo, M., Department of Radiology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Rahardja, R.R., Department of Radiology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Yanuar, A., Department of Neurology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Prihartono, J., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Setiawan, S.I., Department of Radiology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia |
Background: Cross-sectional area (CSA) measurement of the ulnar nerve in the adult population by using ultrasonography (US) at elbow extension and flexion has previously been reported, but not much evidence showed a significant difference between elbow extension and flexion position. Purpose: To compare the ulnar nerve CSA between elbow extension and flexion position. Methods: A comparative cross-sectional study was conducted by involving 36 healthy adults with normally functioning ulnar nerve proven by Nerve Conduction Study (NCS) or Electroneurography. The ulnar nerve CSA was measured on each elbow by using US at the level of the medial epicondyle, 2 cm distal and 2 cm proximal from the medial epicondyle. Results: The average ulnar nerve CSA at the medial epicondyle, 2 cm distal and proximal to the medial epicondyle at elbow extension respectively were 5.95 ± 0.74 mm2, 6.27 ± 0.92 mm2, and 5.92 ± 0.73 mm2. At elbow flexion, the average ulnar nerve CSA at the positions was 5.70 ± 0.83 mm2, 5.23 ± 0.87 mm2, dan 5.73 ± 0.71 mm2 respectively. The CSA of the ulnar nerve at elbow extension was significantly larger compared to the flexion position in the three areas observed in this study (p < 0.001). Conclusion: The CSA of the ulnar nerve at elbow extension position was larger compared to the flexion position. Elbow position should be considered in measuring CSA of the ulnar nerve. © 2021 The Author(s) |
Cross-sectional area; Medial epicondyle; Ulnar nerve; Ultrasonography |
adult; article; clinical article; controlled study; cross-sectional study; echography; elbow flexion; electroneurography; female; human; human experiment; male; nerve conduction; ulnar nerve |
Elsevier Ltd |
23520477 |
|
|
Article |
Q3 |
490 |
10260 |
|
|
