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Riset dan Pengabdian Masyarakat Do Research Sosial Service and Innovation

Id	Authors	Author S Id	Title	Year	Source Title	Volume	Issue	Art No	Page Start	Page End	Cited By	Link	Affiliations	Authors With Affiliations	Abstract	Author Keywords	Index Keywords	Publisher	Issn	Pubmed Id	Document Type	Sjr Best Quartile	Sjr	Sjr Rank
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721	Rahyussalim A.J., Nugroho A., Zufar M.L.L., Fathurrahman I., Kurniawati T.	55212166100;57211502355;57216349850;57252957500;55213290600;	Integration of Umbilical Cord Mesenchymal Stem Cell Application in Hydroxyapatite-Based Scaffolds in the Treatment of Vertebral Bone Defect due to Spondylitis Tuberculosis: A Translational Study	2021	Stem Cells International	2021		9928379				https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114598250&doi=10.1155%2f2021%2f9928379&partnerID=40&md5=4e40b6a1b5d793e962718a6b68d67fa0	Department of Orthopaedic and Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Stem Cells and Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia	Rahyussalim, A.J., Department of Orthopaedic and Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia, Stem Cells and Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Nugroho, A., Department of Orthopaedic and Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Zufar, M.L.L., Department of Orthopaedic and Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Fathurrahman, I., Department of Orthopaedic and Traumatology, Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Kurniawati, T., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia, Stem Cells and Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia	Background. Vertebral bone defect represents one of the most commonly found skeletal problems in the spine. Progressive increase of vertebral involvement of skeletal tuberculosis (TB) is reported as the main cause, especially in developed countries. Conventional spinal fusion using bone graft has been associated with donor-site morbidity and complications. We reported the utilization of umbilical cord mesenchymal stem cells (UC-MSCs) combined with hydroxyapatite (HA) based scaffolds in treating vertebral bone defect due to spondylitis tuberculosis. Materials and Methods. Three patients with tuberculous spondylitis in the thoracic, thoracolumbar, or lumbar region with vertebral body collapse of more than 50 percent were included. The patient underwent a 2-stage surgical procedure, consisting of debridement, decompression, and posterior stabilization in the first stage followed by anterior fusion using the lumbotomy approach at the second stage. Twenty million UC-MSCs combined with HA granules in 2 cc of saline were transplanted to fill the vertebral bone defect. Postoperative alkaline phosphatase level, quality of life, and radiological healing were evaluated at one-month, three-month, and six-month follow-up. Results. The initial mean ALP level at one-month follow-up was 48.33±8.50 U/L. This value increased at the three-month follow-up but decreased at the six-month follow-up time, 97±8.19 U/L and 90.33±4.16 U/L, respectively. Bone formation of 50-75% of the defect site with minimal fracture line was found. Increased bone formation comprising 75-100% of the total bone area was reported six months postoperation. A total score of the SF-36 questionnaire showed better progression in all 8 domains during the follow-up with the mean total score at six months of 2912.5±116.67 from all patients. Conclusion. Umbilical cord mesenchymal stem cells combined with hydroxyapatite-based scaffold utilization represent a prospective alternative therapy for bone formation and regeneration of vertebral bone defect due to spondylitis tuberculosis. Further clinical investigations are needed to evaluate this new alternative. © 2021 Ahmad Jabir Rahyussalim et al.		alkaline phosphatase; hydroxyapatite; adult; Article; bone defect; bone regeneration; clinical article; female; healing; human; male; ossification; quality of life; spinal cord decompression; spine fusion; spine stabilization; surgical approach; surgical debridement; tuberculous spondylitis; umbilical cord mesenchymal stem cell; vertebral bone defect	Hindawi Limited	16879678		Article	Q2	1205	3287	View
722	Haifa G.Z., Wardoyo S.	57249982200;57211106608;	Surgical management in tetralogy of Fallot with rare unilateral pulmonary anomalies: A literature review	2021	Asian Cardiovascular and Thoracic Annals							https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114401204&doi=10.1177%2f02184923211039732&partnerID=40&md5=777078337b7532f398e346223b7685f6	Training Program of Thoracic, Cardiac and Vascular Surgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General Hospital, Indonesia; Department of Thoracic, Cardiac and Vascular Surgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General Hospital, Indonesia	Haifa, G.Z., Training Program of Thoracic, Cardiac and Vascular Surgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General Hospital, Indonesia; Wardoyo, S., Department of Thoracic, Cardiac and Vascular Surgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General Hospital, Indonesia	Tetralogy of Fallot with unilateral pulmonary anomalies such as the unilateral absence of pulmonary artery or unilateral pulmonary agenesis is an extremely rare complex congenital heart anomaly. There is no established surgical algorithm for tetralogy of Fallot with concomitant unilateral pulmonary anomalies. This condition is still challenging, especially in the surgical field. In this review we also present our experiences in our center, Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia. This literature review aimed to discuss systematic treatment options and hoped to help the decision-making process when surgeons face these rare anomalies. © The Author(s) 2021.	Tertralogy of Fallot; unilateral absence of pulmonary artery; unilateral pulmonary agenesis; unilateral pulmonary anomalies		SAGE Publications Inc.	02184923		Review	Q3	203	19132	View
723	Rohsiswatmo R., Widodo A.D., Munasir Z., Medise B.E.	55533574600;57117722400;7801694370;57226215370;	Prebiotic supplementation supports immunity & growth-development in preterm infants: A review and expert perspectives	2021	Bali Medical Journal	10	2		785	792		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114340415&doi=10.15562%2fbmj.v10i2.2490&partnerID=40&md5=cffe54e9756788dc9eeb8ca22d1e3c5a	Department of Child Health, Faculty of Medicine, Universitas Indonesia – Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Harapan Kita National Center for Woman and Child Health Care, Jakarta, Indonesia	Rohsiswatmo, R., Department of Child Health, Faculty of Medicine, Universitas Indonesia – Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Widodo, A.D., Harapan Kita National Center for Woman and Child Health Care, Jakarta, Indonesia; Munasir, Z., Department of Child Health, Faculty of Medicine, Universitas Indonesia – Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Medise, B.E., Department of Child Health, Faculty of Medicine, Universitas Indonesia – Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia	Preterm birth still causes significant mortality and morbidity in newborns, despite modern advancements in preterm care. The gut microbiota is the most significant microbial colonization in the human body and plays a significant role in supporting a healthy body. Preterm infants are susceptible to gut dysbiosis, which is thought to contribute to the many adverse outcomes of prematurity, such as necrotizing enterocolitis (NEC), late-onset sepsis (LOS), and developmental delays. Human breast milk is considered the ideal nutrition source for newborns and can help create ideal microbiota in preterm infants. Breast milk contains human milk oligosaccharides (HMO), prebiotics that promote beneficial bacteria growth, absent in cow’s milk. Supplementation of non-milk oligosaccharides such as long-chain fructo-oligosaccharides (lcFOS) and small-chain galacto-oligosaccharides (scGOS) in formula milk for preterm infants is found to be beneficial with a favourable safety profile. This review discusses gut microbiota in preterm neonates, its role in developing immune systems, growth and development, and the benefits of prebiotic supplementation. © 2021, Sanglah General Hospital. All rights reserved.	Development; Growth; Immunity; Prebiotic; Prematurity; Preterm birth		Sanglah General Hospital	20891180		Review	#N/A	#N/A	#N/A	View
724	Gunawan H., Kamilia A., Menaldi S.L., Marissa M., Prakoeswa C.R.S., Alinda M.D., Widasmara D., Basuki S., Anum Q., Ariani T., Mamuaja E.H., Rusyati L.M.M.	55553742589;57201077194;57192918198;57210795916;57189894608;57202009260;57191841830;57221775070;57246220800;57246220900;57246221000;35724714700;	Characteristics of grade 2 disability in indonesian children with leprosy: A five-year multicenter retrospective study	2021	Clinical, Cosmetic and Investigational Dermatology	14			1149	1153		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114228929&doi=10.2147%2fCCID.S325858&partnerID=40&md5=d2179cc77df886c28de43e2ca3ed6dd3	Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran, Hasan Sadikin Hospital, Bandung, Indonesia; Indonesian Leprosy Study Group – Indonesian Society of Dermatology and Venereology, Jakarta, Indonesia; Indonesian College of Dermatology and Venereology, Jakarta, Indonesia; Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga, Soetomo Hospital, Surabaya, Indonesia; Department of Dermatology and Venereology, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia; Department of Dermatology and Venereology, Faculty of Medicine, Universitas Andalas, Padang, Indonesia; Department of Dermatology and Venereology, Faculty of Medicine, Universitas Sam Ratulangi, Prof. R. D. Kandou Hospital, Manado, Indonesia; Department of Dermatology and Venereology, Faculty of Medicine, Universitas Udayana, Bali, Indonesia	Gunawan, H., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran, Hasan Sadikin Hospital, Bandung, Indonesia, Indonesian Leprosy Study Group – Indonesian Society of Dermatology and Venereology, Jakarta, Indonesia, Indonesian College of Dermatology and Venereology, Jakarta, Indonesia; Kamilia, A., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran, Hasan Sadikin Hospital, Bandung, Indonesia, Indonesian Leprosy Study Group – Indonesian Society of Dermatology and Venereology, Jakarta, Indonesia; Menaldi, S.L., Indonesian Leprosy Study Group – Indonesian Society of Dermatology and Venereology, Jakarta, Indonesia, Indonesian College of Dermatology and Venereology, Jakarta, Indonesia, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Marissa, M., Indonesian Leprosy Study Group – Indonesian Society of Dermatology and Venereology, Jakarta, Indonesia, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Prakoeswa, C.R.S., Indonesian Leprosy Study Group – Indonesian Society of Dermatology and Venereology, Jakarta, Indonesia, Indonesian College of Dermatology and Venereology, Jakarta, Indonesia, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga, Soetomo Hospital, Surabaya, Indonesia; Alinda, M.D., Indonesian Leprosy Study Group – Indonesian Society of Dermatology and Venereology, Jakarta, Indonesia, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga, Soetomo Hospital, Surabaya, Indonesia; Widasmara, D., Indonesian Leprosy Study Group – Indonesian Society of Dermatology and Venereology, Jakarta, Indonesia, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia; Basuki, S., Indonesian Leprosy Study Group – Indonesian Society of Dermatology and Venereology, Jakarta, Indonesia, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia; Anum, Q., Indonesian Leprosy Study Group – Indonesian Society of Dermatology and Venereology, Jakarta, Indonesia, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Andalas, Padang, Indonesia; Ariani, T., Indonesian Leprosy Study Group – Indonesian Society of Dermatology and Venereology, Jakarta, Indonesia, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Andalas, Padang, Indonesia; Mamuaja, E.H., Indonesian Leprosy Study Group – Indonesian Society of Dermatology and Venereology, Jakarta, Indonesia, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Sam Ratulangi, Prof. R. D. Kandou Hospital, Manado, Indonesia; Rusyati, L.M.M., Indonesian Leprosy Study Group – Indonesian Society of Dermatology and Venereology, Jakarta, Indonesia, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Udayana, Bali, Indonesia	Background: One of the indicators of achieved leprosy control is lower new cases of leprosy with grade 2 disability (G2D), while zero new pediatric case with G2D is one of the targets of The Global Leprosy Strategy. This study aimed to describe the characteristics of leprosy in children with G2D from seven provincial hospitals in Indonesia, spanning a period of five years. Methods: This was a descriptive and retrospective study with cross-sectional design. Data were obtained from the medical records of leprosy-affected children in seven provincial hospitals in Indonesia between January 2014 and December 2019 using a total sampling method. Data obtained include characteristics of patients, clinical manifestations, and profile of leprosy in children with G2D. Results: From the 132 data of childhood leprosy retrieved, male (58.33%), age group of 13– 14 years (47.73%), and borderline tuberculoid leprosy (34.09%) comprised the majority of patients. Most of the patients had anesthetic macules as the initial manifestation. The results showed 20 (15.15%) children had G2D. Hands were the most common site affected (50.00%), manifested as claw hands, contractures, atrophy of thenar and hypothenar muscles, and pseudomutilation. Foot drop was seen in five (62.50%) children, and lagophthalmos was seen in one child with leprosy. Conclusion: This study shows that G2D is observed in 15.15% Indonesian children with leprosy at the time of diagnosis, which mostly occurs on the hands in the form of claw hands. Foot disabilities were also observed, most commonly as foot drop, while lagophthalmos was present with disabilities in the eyes. Disability due to leprosy in children really exists. The commitment of all health care services and related institutions is needed in order to reduce the incidence of disability due to leprosy in children. © 2021 Gunawan et al.	Children; Grade 2 disability; Leprosy	adolescent; Article; borderline leprosy; child; claw hand; contracture; cross-sectional study; disability; female; grade 2 disability; human; lagophthalmos; leprosy; major clinical study; male; medical record review; muscle atrophy; peroneus nerve paralysis; preschool child; retrospective study; school child; tuberculoid leprosy	Dove Medical Press Ltd	11787015		Article	Q2	730	6764	View
725	Dakota I., Munawar M., Pranata R., Raffaello W.M., Sukmawan R.	55796663700;57240564000;57201973901;57219975426;8651025300;	Diagnostic prediction model in subjects with low-risk unstable angina pectoris/Non-ST Segment Elevation Myocardial Infarction	2021	European Review for Medical and Pharmacological Sciences	25	16		5145	5152		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113915274&doi=10.26355%2feurrev_202108_26528&partnerID=40&md5=c20c979784718826df68abcc9a197526	Department of Cardiology and Vascular Medicine, National Cardiovascular Center Harapan Kita, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Binawaluya Cardiac Hospital, Jakarta, Indonesia; Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia	Dakota, I., Department of Cardiology and Vascular Medicine, National Cardiovascular Center Harapan Kita, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Munawar, M., Binawaluya Cardiac Hospital, Jakarta, Indonesia; Pranata, R., Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Raffaello, W.M., Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Sukmawan, R., Binawaluya Cardiac Hospital, Jakarta, Indonesia	OBJECTIVE: This study aims to construct a prediction model based on non-invasive examination and cardiovascular risk factors, to predict the presence of coronary artery disease (CAD) and its severity in patients with low-risk unstable angina pectoris (UAP)/ Non-ST Segment Elevation Myocardial Infarction (NSTEMI). PATIENTS AND METHODS: This cross-sectional study aimed to assess the association between non-invasive examinations and cardiovascular risk factors in predicting CAD. Model constructed based on non-invasive assessment and cardiovascular risk factors was compared to coronary angiography, the reference standard. RESULTS: This study included 104 patients, comprising 60 men and 44 women, who fulfilled the inclusion criteria. The mean age was 52.3 (6.8) years. Two diagnostic prediction models were constructed after series of analyses. The main model consists of NO, CIMT, history of smoking, and Age-Gender, while the alternative model consists of CIMT, history of smoking, and Age-Gender. The main model has AUC of 74.5% (95% CI: 64.9-84.1), sensitivity of 72.7% (95% CI: 57.2-85.0), specificity 65.0% (95% CI: 51.6 -76.9 for a cut-off point of 74.5. While the alternative model has 69.0% AUC (95% CI: 58.9-79.1), sensitivity of 65.9% (95%: 50.1-79, 5), a specificity of 56.7% (95% CI: 43.2-69.4) for a cut-off point of 69. The main model and the alternative model have similar diagnostic prediction performance based on the ROC comparison test (p = 0.70). CONCLUSIONS: Based on these results, we conclude that NO, CIMT, smoking history, and age-gender have a value of diagnostic validity in subjects with low-risk UAP/NSTEMI. © 2021 Verduci Editore s.r.l. All rights reserved.	Acute coronary syndrome; Coronary artery disease; Diagnosis; Non-invasive; Unstable angina pectoris	nitric oxide; adult; age distribution; Article; cardiovascular risk factor; carotid intima-media thickness; coronary angiography; coronary artery disease; cross-sectional study; diagnostic test accuracy study; diagnostic value; disease risk assessment; disease severity; female; Gensini score; human; low risk patient; major clinical study; male; non invasive measurement; non ST segment elevation myocardial infarction; prediction; receiver operating characteristic; sensitivity and specificity; sex difference; smoking; unstable angina pectoris	Verduci Editore s.r.l	11283602	34486689	Article	Q2	768	6336	View
726	Kim Y., Ahmed E., Ascher N., Danguilan R., Hooi L.S., Hustrini N.M., Kim Y.H., Kute V., Rosete-Liquete R.M.O., Ma M., Mannon R.B., Nakagawa Y., Od-Erdne L., Ramesh V., Rashid H.U., Thangaraju S., Thwin K.T., Vathsala A., West L., Win K.K., Ahn C., Wong G.	57194114108;57209626753;35394192500;56073507800;6603696990;57200424892;7410196419;36632470600;6507576169;37034386700;7003807110;57236289600;57236003300;57205980938;7102095343;57192114135;57193627441;7003714214;7103226990;57235723800;7201986669;23974794800;	Meeting Report: First State of the Art Meeting on Gender Disparity in Kidney Transplantation in the Asia-Pacific	2021	Transplantation				1888	1891		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113766902&doi=10.1097%2fTP.0000000000003841&partnerID=40&md5=9bfb17e13ffa1ac91810ab03036b4871	Department of Internal Medicine, Inje University, Busan Paik Hospital, Busan, South Korea; Department of Nephrology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan; Division of Transplant Surgery, University of California San Francisco, San Francisco, CA, United States; National Kidney and Transplant Institute, Manila, Quezon City, Philippines; Department of Nephrology and Medicine, Sultanah Aminah Hospital, Johor Bahru, Malaysia; Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Internal Medicine, Inje University, Busan Paik Hospital, Busan, South Korea; Nephrology and Transplantation, Institute of Kidney Diseases and Research Center, Dr. HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Gujarat University of Transplantation, Sciences, Ahmedabad, India; National Kidney and Transplant Institute, Philippines; Department of Medicine, Queen Mary Hospital, Hong Kong, Hong Kong; Division of Nephrology, Department of Medicine, University of Nebraska Medical Center, Omaha, NE, United States; Division of Urology, Juntendo University, Tokyo, Japan; Department of Nephrology, First Central Hospital of Mongolia, Organ Transplantation Center, Ulaanbaatar, Mongolia; National Organ and Tissue Transplant Organisation, DGHS, Ministry of Health and Family Welfare, Vardhman Mahavir Medical College, Safdarjung Hospital, New Delhi, India; Department of Nephrology, Kidney Foundation Hospital and Research Institute, Dhaka, Bangladesh; Department of Renal Medicine, Singapore General Hospital, Singapore, Singapore; Department of Renal Medicine, University of Medicine (I), Yangon, Myanmar; Division of Nephrology, National University of Singapore, Singapore, Singapore; Department of Pediatrics, University of Alberta, Edmonton, AB, Canada; Department of Nephrology, Specialty Hospital, Yangon, Myanmar; Division of Nephrology, National Medical Center, Seoul, South Korea; Sydney School of Public Health, University of Sydney, Sydney, NSW, Australia; Centre for Renal and Transplant Research, Westmead Hospital, Sydney, NSW, Australia	Kim, Y., Department of Internal Medicine, Inje University, Busan Paik Hospital, Busan, South Korea; Ahmed, E., Department of Nephrology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan; Ascher, N., Division of Transplant Surgery, University of California San Francisco, San Francisco, CA, United States; Danguilan, R., National Kidney and Transplant Institute, Manila, Quezon City, Philippines; Hooi, L.S., Department of Nephrology and Medicine, Sultanah Aminah Hospital, Johor Bahru, Malaysia; Hustrini, N.M., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Kim, Y.H., Department of Internal Medicine, Inje University, Busan Paik Hospital, Busan, South Korea; Kute, V., Nephrology and Transplantation, Institute of Kidney Diseases and Research Center, Dr. HL Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Gujarat University of Transplantation, Sciences, Ahmedabad, India; Rosete-Liquete, R.M.O., National Kidney and Transplant Institute, Philippines; Ma, M., Department of Medicine, Queen Mary Hospital, Hong Kong, Hong Kong; Mannon, R.B., Division of Nephrology, Department of Medicine, University of Nebraska Medical Center, Omaha, NE, United States; Nakagawa, Y., Division of Urology, Juntendo University, Tokyo, Japan; Od-Erdne, L., Department of Nephrology, First Central Hospital of Mongolia, Organ Transplantation Center, Ulaanbaatar, Mongolia; Ramesh, V., National Organ and Tissue Transplant Organisation, DGHS, Ministry of Health and Family Welfare, Vardhman Mahavir Medical College, Safdarjung Hospital, New Delhi, India; Rashid, H.U., Department of Nephrology, Kidney Foundation Hospital and Research Institute, Dhaka, Bangladesh; Thangaraju, S., Department of Renal Medicine, Singapore General Hospital, Singapore, Singapore; Thwin, K.T., Department of Renal Medicine, University of Medicine (I), Yangon, Myanmar; Vathsala, A., Division of Nephrology, National University of Singapore, Singapore, Singapore; West, L., Department of Pediatrics, University of Alberta, Edmonton, AB, Canada; Win, K.K., Department of Nephrology, Specialty Hospital, Yangon, Myanmar; Ahn, C., Division of Nephrology, National Medical Center, Seoul, South Korea; Wong, G., Sydney School of Public Health, University of Sydney, Sydney, NSW, Australia, Centre for Renal and Transplant Research, Westmead Hospital, Sydney, NSW, Australia	[No abstract available]			Lippincott Williams and Wilkins	00411337	34416749	Article	Q1	1450	2398	View
727	Pratomo I.P., Noor D.R., Kusmardi K., Rukmana A., Paramita R.I., Erlina L., Fadilah F., Gayatri A., Fitriani M., Purnomo T.T.H., Ariane A., Heryanto R., Tedjo A.	57192904477;57214096801;56966625300;35491487100;54882436900;57190181680;56966708600;57204275086;57233517300;57234248500;57210643323;23392757600;57189320451;	Xanthine Oxidase-Induced Inflammatory Responses in Respiratory Epithelial Cells: A Review in Immunopathology of COVID-19	2021	International Journal of Inflammation	2021		1653392			1	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113632856&doi=10.1155%2f2021%2f1653392&partnerID=40&md5=37c46cd8f6ff191ba785fa8abb7052a3	Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; COVID-19 Task Force-Pulmonology and Respiratory Medicine Unit, Universitas Indonesia University Hospital, Universitas Indonesia, Depok, Indonesia; Bioinformatics Core Facilities, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Human Cancer Research Center, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Pathology Anatomy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Drug Development Research Cluster, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Microbiology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Medical Chemistry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Master's Programme in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Dki Jakarta, Depok, Indonesia; Department of Pharmacology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Universitas Indonesia University Hospital, Universitas Indonesia, Depok, Indonesia; Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Dr. Cipto Mangunkusumo Hospital, Indonesia; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Ipb University, Bogor, Indonesia; Tropical Biopharmaca Research Center, Ipb University, Bogor, Indonesia	Pratomo, I.P., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, COVID-19 Task Force-Pulmonology and Respiratory Medicine Unit, Universitas Indonesia University Hospital, Universitas Indonesia, Depok, Indonesia, Bioinformatics Core Facilities, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Noor, D.R., Human Cancer Research Center, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Kusmardi, K., Human Cancer Research Center, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Pathology Anatomy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Drug Development Research Cluster, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Rukmana, A., Department of Microbiology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Paramita, R.I., Bioinformatics Core Facilities, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Medical Chemistry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Master's Programme in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Dki Jakarta, Depok, Indonesia; Erlina, L., Bioinformatics Core Facilities, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Medical Chemistry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Master's Programme in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Dki Jakarta, Depok, Indonesia; Fadilah, F., Bioinformatics Core Facilities, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Medical Chemistry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Master's Programme in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Dki Jakarta, Depok, Indonesia; Gayatri, A., Department of Pharmacology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Fitriani, M., Universitas Indonesia University Hospital, Universitas Indonesia, Depok, Indonesia; Purnomo, T.T.H., Universitas Indonesia University Hospital, Universitas Indonesia, Depok, Indonesia; Ariane, A., Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Dr. Cipto Mangunkusumo Hospital, Indonesia; Heryanto, R., Department of Chemistry, Faculty of Mathematics and Natural Sciences, Ipb University, Bogor, Indonesia, Tropical Biopharmaca Research Center, Ipb University, Bogor, Indonesia; Tedjo, A., Drug Development Research Cluster, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Medical Chemistry, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Master's Programme in Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Dki Jakarta, Depok, Indonesia	Xanthine oxidase (XO) is an enzyme that catalyzes the production of uric acid and superoxide radicals from purine bases: hypoxanthine and xanthine and is also expressed in respiratory epithelial cells. Uric acid, which is also considered a danger associated molecule pattern (DAMP), could trigger a series of inflammatory responses by activating the inflammasome complex path and NF-B within the endothelial cells and by inducing proinflammatory cytokine release. Concurrently, XO also converts the superoxide radicals into hydroxyl radicals that further induce inflammatory responses. These conditions will ultimately sum up a hyperinflammation condition commonly dubbed as cytokine storm syndrome (CSS). The expression of proinflammatory cytokines and neutrophil chemokines may be reduced by XO inhibitor, as observed in human respiratory syncytial virus (HRSV)-infected A549 cells. Our review emphasizes that XO may have an essential role as an anti-inflammation therapy for respiratory viral infection, including coronavirus disease 2019 (COVID-19). © 2021 Irandi Putra Pratomo et al.		allopurinol; uric acid; xanthine oxidase; airway epithelium cell; antiinflammatory activity; catalysis; coronavirus disease 2019; cytokine release; enzyme activity; human; hypoxia; immunopathology; inflammation; neutrophil; nonhuman; pathogenesis; protein function; protein targeting; Review; RNA virus infection	Hindawi Limited	20908040		Review	Q2	1106	3761	View
728	Amin L.Z., Amin H.Z., Amin Z.	57193005548;56217714300;16309125900;	Beta-blocker attenuates cardiotoxicity related anthracycline usage	2021	Journal of the Medical Association of Thailand	104	8		1389	1392		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113310208&doi=10.35755%2fjmedassocthai.2021.08.9268&partnerID=40&md5=ee18aa74520b3a2ce8f163a390c84499	Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Indonesia	Amin, L.Z., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Indonesia; Amin, H.Z., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Indonesia; Amin, Z., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Indonesia	To summarize the recent trials and studies of the role of beta-blocker on the treatment for cancer patients treated with anthracycline to decrease morbidity and mortality rate. Good management of cancer will result in large numbers of cancer survivors. On the other hand, cancer therapy also has side effects, one of which is cardiotoxicity. Cardiotoxicity could reduce therapy effectiveness, hence, increase disease progression and mortality rate. Anthracyclines is one of the chemotherapy agents with cardiotoxicity as a side effect. Beta-blocker has the ability to reduce cardiotoxicity due to anthracyclines usage. © JOURNAL OF THE MEDICAL ASSOCIATION OF THAILAND.	Anthracyclines; Beta-blocker; Cardiotoxicity	alprenolol; amino terminal pro brain natriuretic peptide; anthracycline; beta adrenergic receptor; beta adrenergic receptor blocking agent; beta arrestin; carvedilol; deubiquitinase; DNA topoisomerase (ATP hydrolysing); doxorubicin; epidermal growth factor receptor; epirubicin; G protein coupled receptor; guanosine triphosphatase; histone deacetylase; hydroxyl radical; nebivolol; peroxisome proliferator; protein p53; reactive nitrogen species; reactive oxygen metabolite; reduced nicotinamide adenine dinucleotide phosphate oxidase; sodium chloride; apoptosis; autophagy (cellular); blood pressure; breast cancer; cancer therapy; cancer tissue; cardiac muscle cell; cardiac stem cell; cardiomyopathy; cardiotoxicity; cardiovascular disease; cardiovascular risk factor; cell death; cell membrane;	Medical Association of Thailand	01252208		Review	#N/A	#N/A	#N/A	View
729	Raharjo S.B., Mustika R., Lydia A., Yanni M., Sulastomo H., Zhuhra R.T., Atmadikoesoemah C.A.	57017880700;57220273147;8451287200;57216309765;57204924380;57220591134;57212145127;	Trainees' perceptions and expectations of formal academic mentoring during the COVID-19 pandemic in Indonesian cardiology residency programs	2021	Journal of Educational Evaluation for Health Professions	18		19				https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113295810&doi=10.3352%2fJEEHP.2021.18.19&partnerID=40&md5=7733f412708826aa1df71dcc04d870df	Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Medical Education Collaboration Cluster, Indonesian Medical Education and Research Institute, Universitas Indonesia, Jakarta, Indonesia; Department of Medical Education, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Kidney and Hypertension Division, Department of Internal Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Cardiology and Vascular Medicine, Faculty of Medicine, Andalas University, Padang, Indonesia; Department of Cardiology and Vascular Medicine, Faculty of Medicine, Sebelas Maret University, Surakarta, Indonesia	Raharjo, S.B., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Medical Education Collaboration Cluster, Indonesian Medical Education and Research Institute, Universitas Indonesia, Jakarta, Indonesia; Mustika, R., Medical Education Collaboration Cluster, Indonesian Medical Education and Research Institute, Universitas Indonesia, Jakarta, Indonesia, Department of Medical Education, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Lydia, A., Medical Education Collaboration Cluster, Indonesian Medical Education and Research Institute, Universitas Indonesia, Jakarta, Indonesia, Kidney and Hypertension Division, Department of Internal Medicine, Universitas Indonesia, Jakarta, Indonesia; Yanni, M., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Andalas University, Padang, Indonesia; Sulastomo, H., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Sebelas Maret University, Surakarta, Indonesia; Zhuhra, R.T., Medical Education Collaboration Cluster, Indonesian Medical Education and Research Institute, Universitas Indonesia, Jakarta, Indonesia; Atmadikoesoemah, C.A., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia	Purpose: During medical residency programs, physicians develop their professional identities as specialists and encounter high expectations in terms of achieving competencies. The responsibilities of medical trainees include caring for patients, balancing work with personal life, and weathering stress, depression, and burnout. Formal academic mentoring programs strive to ease these burdens. The coronavirus disease 2019 (COVID-19) pandemic has altered the trainee-academic mentor relationship, and solutions are needed to address these challenges. The present study aimed to evaluate the formal academic mentoring process through trainees' perceptions and expectations of formal mentoring programs during COVID-19 in Indonesian cardiology residency programs. Methods: This cross-sectional study used a self-administered online questionnaire to capture trainees' perceptions and expectations regarding academic mentoring programs in 3 cardiology residency programs in Indonesia from October to November 2020. The questionnaire was developed before data collection. Perceptions of the existing mentoring programs were compared with expectations. Results: Responses were gathered from 169 out of 174 residents (response rate, 97.3%). Most trainees reported having direct contact with COVID-19 patients (88.82%). They stated that changes had taken place in the mode and frequency of communication with their academic advisors during the pandemic. Significant differences were found between trainees' perceptions of the existing mentoring programs and their expectations for academic mentoring programs (P<0.001). Conclusion: Despite the challenges of interacting with their academic mentors, trainees still perceived academic mentors as a vital resource. Study programs need to consider trainees' expectations when designing academic mentoring programs. © 2021, Korea Health Personnel Licensing Examination Institute (cc) This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.	Communication; COVID-19; Indonesia; Internship and residency; Mentoring	cardiology; cross-sectional study; human; Indonesia; medical education; mentor; mentoring; motivation; pandemic; perception; questionnaire; Cardiology; COVID-19; Cross-Sectional Studies; Humans; Indonesia; Internship and Residency; Mentoring; Mentors; Motivation; Pandemics; Perception; SARS-CoV-2; Surveys and Questionnaires	Korea Health Personnel Licensing Examination Institute	19755937	34399567	Article	Q2	397	12204	View
730	Atmakusuma T.D., Hasibuan F.D., Purnamasari D.	57216961785;57227028400;36519537700;	The correlation between iron overload and endocrine function in adult transfusion-dependent beta-thalassemia patients with growth retardation	2021	Journal of Blood Medicine	12			749	753		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113290577&doi=10.2147%2fJBM.S325096&partnerID=40&md5=dd85b4afdd08b0c54b3857a4d69f80f1	Division of Hematology-Medical Oncology, Department of Internal Medicine, Dr. Cipto Mangunkusumo General Hospital/Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Division of Hematology-Medical Oncology, Department of Internal Medicine, Yarsi Hospital, Jakarta, Indonesia; Endocrine and Metabolic Division, Department of Internal Medicine, Dr. Cipto Mangunkusumo General Hospital/Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia	Atmakusuma, T.D., Division of Hematology-Medical Oncology, Department of Internal Medicine, Dr. Cipto Mangunkusumo General Hospital/Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Hasibuan, F.D., Division of Hematology-Medical Oncology, Department of Internal Medicine, Yarsi Hospital, Jakarta, Indonesia; Purnamasari, D., Endocrine and Metabolic Division, Department of Internal Medicine, Dr. Cipto Mangunkusumo General Hospital/Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia	Background: Iron overload is a major problem in patients with transfusion-dependent beta-thalassemia (TDT). Reports on the correlation between iron overload and endocrine function with growth retardation in such a population in Indonesia have not been established. Therefore, this study aims to obtain a profile of iron load and endocrine function of adult transfusion dependent beta-thalassemia patients and their correlation with growth retardation. Methods: A cross-sectional study was performed, involving adult homozygous and HbE beta-thalassemia patients receiving blood transfusions at the Cipto Mangunkusumo Hospital, Jakarta. Iron overload was represented by serum ferritin (FS) and transferrin saturation (TS), while the endocrine function was examined by the Thyroid Stimulating Hormone-sensitive (TSHs), free T4 (fT4), and insulin-like growth factor-1 (IGF-1). The results were analyzed using bivariate analysis plus Pearson and Spearman correlation tests. Results: In general, 58 subjects were selected from 224 adult transfusion dependent beta-thalassemia patients, consisting of 31 males (53.4%) and 27 females (46.6%). Furthermore, their median age was 21 (18–24) years, while the subclinical hypothyroid proportion was 32.7% and low IGF-1 levels were detected in 79.3% of the total population. There was a weak negative correlation between FS and fT4 (Spearman rho=−0.361; p=0.003), as well as IGF-1 (Spearman rho=−0.313; p=0.008), but FS and TSHs had no correlation (Spearman rho=0.074; p=0.29). Also, there was no correlation between ST with TSHs (Spearman rho=0.003; p=0.492), fT4 (Spearman rho=0.018; p=0.448), and IGF-1 (Spearman rho= −0.142; p=0.143). Conclusion: Based on serum ferritin, iron overload is discovered to have a negative correlation with free T4 and insulin-like growth factor-1. © 2021 Atmakusuma et al.	FT4; IGF-1; Serum ferritin; Transferrin saturation; Transfusion-dependent thalassemia; TSHs	ferritin; hemoglobin; somatomedin C; thyroid antibody; thyroid stimulating immunoglobulin; thyrotropin; transferrin; adult; Article; body mass; chemiluminescence immunoassay; controlled study; correlation analysis; cross-sectional study; endocrine disease; endocrine function; female; ferritin blood level; free thyroxine index; gene expression; hemoglobin E-beta thalassemia; high performance liquid chromatography; human; human tissue; hypothyroidism; iron binding capacity; iron load; iron overload; major clinical study; male; nuclear magnetic resonance imaging; prevalence; protein expression; subclinical hypothyroidism; thyroid function; transferrin saturation; transfusion dependent thalassemia	Dove Medical Press Ltd	11792736		Article	Q3	676	7401	View

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