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154	Harzif A.K., Maidarti M., Shadrina A., Saroyo Y.B.	57191493435;56320510400;57195984988;57164888400;	Cesarean scar pregnancy management: Different approach for different situation; A case series	2021	Annals of Medicine and Surgery	70		102808			1	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115147645&doi=10.1016%2fj.amsu.2021.102808&partnerID=40&md5=0723e394f168f0efeec1c2d427f0cf19	Obstetric and Gynecology Department, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Indonesia	Harzif, A.K., Obstetric and Gynecology Department, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Indonesia; Maidarti, M., Obstetric and Gynecology Department, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Indonesia; Shadrina, A., Obstetric and Gynecology Department, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Indonesia; Saroyo, Y.B., Obstetric and Gynecology Department, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Indonesia	The incidence of caesaean scar pregnancy (CSP) increases since the cesarean delivery rate had increased as well. Diagnosing of CSP was also a challenge to identify the type of CSP which important things for choosing the right management. The CSP could be classified into two types, which are endogenous and exogenous. While the management was dependent into the types, such as suction curettage, resection, and also hysterectomy. This paper showed cases of cesarean scar pregnancy in Cipto Mangunkusumo General Hospital, in one year. © 2021 The Authors	Case series; Cesarean scar pregnancy; Cesarean section	Article; bleeding; case report; cesarean section; clinical article; conception; curettage; ectopic pregnancy; female; gestational age; human; hypovolemic shock; hysterectomy; laparotomy; pregnancy; preoperative period; scar; suction; ultrasound	Elsevier Ltd	20490801		Article	Q3	391	12334	View
156	Yoanita R., Gunardi H., Rohsiswatmo R., Setyanto D.B.	57257403000;56510252700;55533574600;57203009929;	Effect of tactile–kinesthetic stimulation on growth, neurobehavior and development among preterm neonates	2021	Journal of Bodywork and Movement Therapies	28			180	186		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114826873&doi=10.1016%2fj.jbmt.2021.06.023&partnerID=40&md5=42e65f10f1f437b31aaa9dd4fdb3559e	Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia; Developmental Behavioural & Community Pediatrics Division, Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia; Neonatology Division, Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia; Pediatric Respirology Division, Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia	Yoanita, R., Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia; Gunardi, H., Developmental Behavioural & Community Pediatrics Division, Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia; Rohsiswatmo, R., Neonatology Division, Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia; Setyanto, D.B., Pediatric Respirology Division, Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Indonesia	Background: Preterm neonates are at risk of delayed growth and development. Hence, early tactile–kinesthetic stimulation (TKS) is required to improve their growth and development. Objective: To evaluate the effect of TKS on growth, neurobehavior and development among preterm neonates. Method: An interventional study was conducted from August 2015 to July 2017 in the neonatal unit of Dr. Cipto Mangunkusumo Hospital. Preterm neonates were recruited via random sampling and divided into two groups (the intervention group and control group). TKS was performed for 15 min, three times a day, for 10 days. The anthropometric measurements, neurobehavior (Dubowitz score) and development (Capute Scale score) of neonates in both groups were assessed. Results: There were 126 preterm neonates (n = 63 in each group). During the 10-day TKS period, the intervention group had a significant increment in weight and length compared to the control group (p < 0.05) at 11–14 days, at term and 3 months. Moreover, increased tone, reflexes, and improvement in behavior based on the Dubowitz score were observed during monitoring. However, the result did not differ significantly (p > 0.05). There was no significant difference in terms of cognitive and language development in both groups (Developmental Quotient of Clinical Linguistic Adaptive Milestone Scale, Developmental Quotient of Clinical Adaptive Test and Full Scale Developmental Quotient scores, p > 0.05). Conclusion: TKS was significantly effective in promoting growth, particularly weight and length, among preterm neonates. However, it did not significantly influence neurobehavior and development at 3 months of chronological age. © 2021 Elsevier Ltd	Growth; Infant behavior; Infant development; Preterm infants; Tactile perception	human; kinesthesia; newborn; prematurity; touch; Humans; Infant, Newborn; Infant, Premature; Kinesthesis; Touch	Churchill Livingstone	13608592	34776139	Article	Q1	467	10672	View
157	Meilia P.D.I., Herkutanto, Atmadja D.S., Cordner S., Eriksson A., Kubat B., Kumar A., Payne-James J.J., Rubanzana W.G., Uhrenholt L., Freeman M.D., Zeegers M.P.	57204065074;57204069374;6507824506;7005870991;7202802446;6602085186;57202849040;7005419201;56514032500;14061357600;34769701500;7003691618;	The PERFORM-P (Principles of Evidence-based Reporting in FORensic Medicine-Pathology version)	2021	Forensic Science International	327		110962				https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114050611&doi=10.1016%2fj.forsciint.2021.110962&partnerID=40&md5=2f9ffc7c51b3342895994d7c7de9fde4	Care and Public Health Research Institute (CAPHRI), Maastricht University Medical Center+, Maastricht, Netherlands; Department of Forensic Medicine and Medicolegal Studies, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; The Victorian Institute of Forensic Medicine, Melbourne, Victoria, Australia; Dept of Community Medicine and Rehabilitation/Forensic Medicine, Umeå University, Umeå, Sweden; Faculty of Health, Medicine and Life Science, Maastricht University, Maastricht, Netherlands; Forensic Medicine and Toxicology, All India Institute of Medical SciencesNew Delhi, India; William Harvey Research Institute, Queen Mary University of London, London, UK, United Kingdom; Department of Epidemiology and Biostatistics, University of Rwanda College of Medicine and Health Sciences, School of Public Health, Kigali, Rwanda; Department of Forensic Medicine, Section of Forensic Pathology, Aarhus University, Aarhus, Denmark	Meilia, P.D.I., Care and Public Health Research Institute (CAPHRI), Maastricht University Medical Center+, Maastricht, Netherlands; Herkutanto, Department of Forensic Medicine and Medicolegal Studies, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Atmadja, D.S., Department of Forensic Medicine and Medicolegal Studies, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Cordner, S., The Victorian Institute of Forensic Medicine, Melbourne, Victoria, Australia; Eriksson, A., Dept of Community Medicine and Rehabilitation/Forensic Medicine, Umeå University, Umeå, Sweden; Kubat, B., Faculty of Health, Medicine and Life Science, Maastricht University, Maastricht, Netherlands; Kumar, A., Forensic Medicine and Toxicology, All India Institute of Medical SciencesNew Delhi, India; Payne-James, J.J., William Harvey Research Institute, Queen Mary University of London, London, UK, United Kingdom; Rubanzana, W.G., Department of Epidemiology and Biostatistics, University of Rwanda College of Medicine and Health Sciences, School of Public Health, Kigali, Rwanda; Uhrenholt, L., Department of Forensic Medicine, Section of Forensic Pathology, Aarhus University, Aarhus, Denmark; Freeman, M.D., Care and Public Health Research Institute (CAPHRI), Maastricht University Medical Center+, Maastricht, Netherlands; Zeegers, M.P., Care and Public Health Research Institute (CAPHRI), Maastricht University Medical Center+, Maastricht, Netherlands	Introduction: Most findings of forensic pathology examinations are presented as written reports. There are currently no internationally accepted recommendations for writing forensic pathology reports. Existing recommendations are also varied and reflect the differences in the scope and role of forensic medical services and local settings in which they are to be implemented. The legal fact-finder thus faces wide variation in the quality of forensic pathology reports, which poses a threat to the reliability of legal decision-making. To address this issue, the development of the “PERFORM-P (Principles of Evidence-based Reporting in FORensic Medicine-Pathology version)” was undertaken. The goal of the PERFORM-P is to provide common practice recommendations adaptable to local requirements to promote evidence-based practice (EBP) in forensic pathology. Methods: An international consensus study was conducted in three phases by (1) developing a long-list of items to be considered in the reporting recommendations, (2) conducting a Delphi process (an iterative survey method to transform individual opinions into group consensus) with international forensic pathologists, and (3) designing the PERFORM-P prototype and its accompanying manual. Results: With assistance from 106 forensic pathologists/forensic medical practitioners from 41 countries, the PERFORM-P was developed. The PERFORM-P consists of a list of 61 items to be included in a forensic pathology report, which is accompanied by its Explanation and Elaboration (E&E) document. Discussion: To prepare forensic pathology (postmortem) reports that incorporate principles of evidence-based practice, internationally accepted recommendations might be helpful. The PERFORM-P identifies recommendations for necessary elements to include in a forensic pathology report. PERFORM-P can be applied to a wide range of matters requiring forensic pathological analysis, acceptable to forensic pathologists from a representative selection of jurisdictions and medico-legal systems. © 2021 The Authors	Delphi study; Evidence-based practice; Forensic medicine; Forensic pathology; Reporting guides	article; consensus; decision making; Delphi study; evidence based practice center; forensic pathology; human; pathologist; reliability; adult; consensus; evidence based practice; forensic pathology; international cooperation; middle aged; practice guideline; questionnaire; research; Adult; Consensus; Delphi Technique; Evidence-Based Practice; Forensic Pathology; Humans; Internationality; Middle Aged; Practice Guidelines as Topic; Research Report; Surveys and Questionnaires	Elsevier Ireland Ltd	03790738	34474199	Article	Q1	912	5047	View
158	Mangunatmadja I., Ismael S., Sastroasmoro S., Suyatna F.D., van Nieuwenhuizen O., Cornelis van Huffelen A.	57195717216;7003712283;6507794136;57303311300;7004334708;57226810329;	Risk factors predicting intractability in focal epilepsy in children under 3 years of age: A cohort study	2021	Epilepsy and Behavior	123		108234				https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112784416&doi=10.1016%2fj.yebeh.2021.108234&partnerID=40&md5=4d05d9ec38151cc168fae550bc699834	Department of Child Health, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Clinical Pharmacology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Child Neurology, University Medical Center Utrecht, Netherlands; Department of Clinical Neurophysiology, University Medical Center Utrecht, Netherlands	Mangunatmadja, I., Department of Child Health, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Ismael, S., Department of Child Health, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Sastroasmoro, S., Department of Child Health, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Suyatna, F.D., Department of Clinical Pharmacology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; van Nieuwenhuizen, O., Department of Child Neurology, University Medical Center Utrecht, Netherlands; Cornelis van Huffelen, A., Department of Clinical Neurophysiology, University Medical Center Utrecht, Netherlands	Background: Focal onset epilepsy carries a higher risk of intractability than generalized onset epilepsy. Knowledge of the risk factors of intractability will help guide the treatment of children with focal epilepsy. In addition to risk factors present at initial diagnosis, the evolution of clinical and electroencephalographic features may also play a role in predicting intractability. Methods: A prospective cohort study was done on children aged one month to three years with newly diagnosed focal epilepsy. Initial treatment of carbamazepine was given according to a standard protocol after assessment of clinical manifestations, neurologic and developmental status, EEG, and brain MRI. Depending on response to therapy, subjects may also receive valproic acid or phenobarbitone following the protocol. Follow-up was done in the second week and every month thereafter. At the end of the study period, seizure type was re-assessed and a repeat neurological and developmental examination and EEG was obtained to evaluate the role of clinical and EEG evolution in predicting intractability. Results: Out of 71 subjects, 21 (29.6%) had intractable epilepsy at the end of the study period. Age of onset (p = 0.216) and neurological status (p = 0.052) were not associated with intractable epilepsy. On logistic regression analysis, evolution of seizure type (p < 0.001; RR 56.45; 95%CI 6.56 to 485.85) and evolution of background EEG rhythm (p < 0.001; RR 56.51; 95%CI 2.77 to 1152.16) were significantly associated with intractable epilepsy. Conclusions: Changes in seizure type and baseline EEG rhythm may predict intractability in children one month to three years of age with focal epilepsy. © 2021	Electroencephalography; Focal epilepsy; Intractable; Seizure	carbamazepine; phenobarbital; valproic acid; anticonvulsive agent; Article; cerebral palsy; child; cohort analysis; electroencephalography; epileptic discharge; focal epilepsy; follow up; human; intractable epilepsy; major clinical study; monotherapy; nuclear magnetic resonance imaging; preschool child; risk factor; focal epilepsy; prospective study; risk factor; Anticonvulsants; Child; Child, Preschool; Cohort Studies; Electroencephalography; Epilepsies, Partial; Humans; Prospective Studies; Risk Factors	Academic Press Inc.	15255050	34416519	Article	Q2	993	4418	View
159	Sun X., Li R., Cai Y., Al-Herz A., Lahiri M., Choudhury M.R., Hidayat R., Suryana B.P.P., Kaneko Y., Fujio K., Van Hung N., Pandya S., Pang L.K., Katchamart W., Sigdel K.R., Paudyal B., Narongroeknawin P., Chevaisrakul P., Sun F., Lu Y., Ho C., Yeap S.S., Li Z., on behalf of APLAR RA SIG group	57211390694;57026629100;56599490900;6508020635;26039213500;55408508400;37067327300;15728721800;8409247100;55029631300;57226144210;7103287746;57226150004;26654177400;56123182100;9244632800;35099091000;57191876780;57201927847;57226146642;57226138308;6701698220;57202324922;	Clinical remission of rheumatoid arthritis in a multicenter real-world study in Asia-Pacific region	2021	The Lancet Regional Health - Western Pacific	15		100240				https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112352039&doi=10.1016%2fj.lanwpc.2021.100240&partnerID=40&md5=ef847be2cdf076f3416d77f746dcd1cd	Department of Rheumatology & Immunology, Peking University People's Hospital, 11 Xizhimen South St.Beijing 100044, China; Department of Rheumatology & Immunology, Peking University Shenzhen Hospital, Shenzhen, China; Rheumatology Unit, Department of Internal Medicine, Al-Amiri Hospital, Kuwait City, Kuwait; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Department of Rheumatology, Bangabandhu Sheikh Mujib Medical UniversityDhaka, Bangladesh; Department of Internal Medicine, Cipto Mangunkusumo National Hospital Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Rheumatology Division, Internal Medicine Department, Brawijaya University - Saiful Anwar Hospital, Indonesia; Division of Rheumatology, Department of Internal Medicine, Keio University School of MedicineTokyo, Japan; Department of Allergy and Rheumatology, Graduate School of Medicine, The University of TokyoTokyo, Japan; Department of Rheumatology, Bach Mai Hospital, Giai Phong Road, Dong Da DistrictHanoi, Viet Nam; Vedanta institute of medical sciences and VS hospital, Ahmedabad, India; Department of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore; Division of Rheumatology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol UniversityBangkok, Thailand; Department of Internal Medicine, Patan Academy of Health Sciences, Kathmandu, Nepal; Division of Rheumatology, Department of Medicine, Phramongkutklao Hospital and College of MedicineBangkok, Thailand; Division of Allergy, Immunology and Rheumatology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol UniversityBangkok, Thailand; Department of Epidemiology and Biostatistics, School of Public Health, Peking University, 38 Xueyuan Road, Haidian DistrictBeijing 100191, China; School of Mathematical Science, Nankai University, No. 94 Weijin Road, Nankai DistrictTianjin 300071, China; Division of Rheumatology, Dept of Medicine, The University of Hong Kong, Hong Kong SAR, Hong Kong; Department of Medicine, Subang Jaya Medical Centre, Selangor, Malaysia	Sun, X., Department of Rheumatology & Immunology, Peking University People's Hospital, 11 Xizhimen South St.Beijing 100044, China; Li, R., Department of Rheumatology & Immunology, Peking University People's Hospital, 11 Xizhimen South St.Beijing 100044, China; Cai, Y., Department of Rheumatology & Immunology, Peking University Shenzhen Hospital, Shenzhen, China; Al-Herz, A., Rheumatology Unit, Department of Internal Medicine, Al-Amiri Hospital, Kuwait City, Kuwait; Lahiri, M., Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Choudhury, M.R., Department of Rheumatology, Bangabandhu Sheikh Mujib Medical UniversityDhaka, Bangladesh; Hidayat, R., Department of Internal Medicine, Cipto Mangunkusumo National Hospital Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Suryana, B.P.P., Rheumatology Division, Internal Medicine Department, Brawijaya University - Saiful Anwar Hospital, Indonesia; Kaneko, Y., Division of Rheumatology, Department of Internal Medicine, Keio University School of MedicineTokyo, Japan; Fujio, K., Department of Allergy and Rheumatology, Graduate School of Medicine, The University of TokyoTokyo, Japan; Van Hung, N., Department of Rheumatology, Bach Mai Hospital, Giai Phong Road, Dong Da DistrictHanoi, Viet Nam; Pandya, S., Vedanta institute of medical sciences and VS hospital, Ahmedabad, India; Pang, L.K., Department of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore; Katchamart, W., Division of Rheumatology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol UniversityBangkok, Thailand; Sigdel, K.R., Department of Internal Medicine, Patan Academy of Health Sciences, Kathmandu, Nepal; Paudyal, B., Department of Internal Medicine, Patan Academy of Health Sciences, Kathmandu, Nepal; Narongroeknawin, P., Division of Rheumatology, Department of Medicine, Phramongkutklao Hospital and College of MedicineBangkok, Thailand; Chevaisrakul, P., Division of Allergy, Immunology and Rheumatology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol UniversityBangkok, Thailand; Sun, F., Department of Epidemiology and Biostatistics, School of Public Health, Peking University, 38 Xueyuan Road, Haidian DistrictBeijing 100191, China; Lu, Y., School of Mathematical Science, Nankai University, No. 94 Weijin Road, Nankai DistrictTianjin 300071, China; Ho, C., Division of Rheumatology, Dept of Medicine, The University of Hong Kong, Hong Kong SAR, Hong Kong; Yeap, S.S., Department of Medicine, Subang Jaya Medical Centre, Selangor, Malaysia; Li, Z., Department of Rheumatology & Immunology, Peking University People's Hospital, 11 Xizhimen South St.Beijing 100044, China; on behalf of APLAR RA SIG group	Background: Clinical remission is an attainable goal for Rheumatoid Arthritis (RA). However, data on RA remission rates from multinational studies in the Asia-Pacific region are limited. We conducted a cross-sectional multicentric study to evaluate the clinical remission status and the related factors in RA patients in the Asia-Pacific region. Methods: RA patients receiving standard care were enrolled consecutively from 17 sites in 11 countries from APLAR RA SIG group. Data were collected on-site by rheumatologists with a standardized case-report form. Remission was analyzed by different definitions including disease activity score using 28 joints (DAS28) based on ESR and CRP, clinical disease activity index (CDAI), simplified disease activity index (SDAI), Boolean remission definition, and clinical deep remission (CliDR). Logistic regression was used to determine related factors of remission. Findings: A total of 2010 RA patients was included in the study, the overall remission rates were 62•3% (DAS28-CRP), 35•5% (DAS28-ESR), 30•8% (CDAI), 26•5% (SDAI), 24•7% (Boolean), and 17•1% (CliDR), respectively, and varied from countries to countries in the Asia-Pacific region. Biological and targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs) prescription rate was low (17•9%). Compared to patients in non-remission, patients in remission had higher rates of b/tsDMARDs usage and lower rates of GC usage. The favorable related factors were male sex, younger age, fewer comorbidities, fewer extra-articular manifestations (EAM), and use of b/tsDMARDs, while treatment with GC was negatively related to remission. Interpretation: Remission rates were low and varied in the Asia-Pacific region. Treatment with b/tsDMARDs and less GC usage were related to higher remission rate. There is an unmet need for RA remission in the Asia-Pacific region. © 2021			Elsevier Ltd	26666065		Article	#N/A	#N/A	#N/A	View
160	Yulian E.D., Siregar N.C., Bajuadji	55983956600;6508087790;57318007000;	Combination of Simvastatin and FAC Improves Response to Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer	2021	Cancer Research and Treatment	53	4		1072	1083	2	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111269220&doi=10.4143%2fcrt.2020.1024&partnerID=40&md5=fe14ed1b791ebc2592f487892c429602	Division of Surgical Oncology, Department of Surgery; Department of Pathology, Dr. Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Surgery, Koja General Hospital, Jakarta, Indonesia	Yulian, E.D., Division of Surgical Oncology, Department of Surgery; Siregar, N.C., Department of Pathology, Dr. Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Bajuadji, Department of Surgery, Koja General Hospital, Jakarta, Indonesia	Purpose The efficacy of neoadjuvant chemotherapy for locally advanced breast cancer (LABC) is limited due to drug resistance and cardiotoxic effects. Preclinical studies have shown that statin induces apoptosis and decreases breast cancer cell growth. This study aims to evaluate the role of statin in combination with fluorouracil, adriamycin, and cyclophosphamide (FAC) therapy in LABC patients. Materials and Methods We undertook a randomized, double-blinded, placebo-controlled trial in two centers of Indonesia. Patients were randomly assigned to FAC plus simvastatin (40 mg/day orally) or FAC plus placebo (40 mg/day) for 21 days. The FAC regimen was repeated every 3 weeks. We evaluated the clinical response, pathological response, and toxicities. Results The objective response rate (ORR) for FAC plus simvastatin was 90% (95% confidence interval [CI], 0.99 to 1.67) by per-protocol analysis. No complete responses (CR) were recorded, but there were 48 partial responses. No significant difference was observed between the two groups with the ORR (p=0.103). The pathological CR rate was 6.25% (2 in simvastatin group and 1 in placebo group). Adverse events in both arms were generally mild, mainly consisted of myotoxicity. Human epidermal growth factor receptor 2 (HER2) expression was a factor related to the success of therapeutic response (odds ratio, 4.2; 95% CI, 1.121 to 15.731; p=0.033). Conclusion This study suggests that simvastatin combined with FAC shows improvements in ORR and pathological response in patients with LABC. Although no statistically significant difference was documented, there was a trend for better activity and tolerability. The addition of 40 mg simvastatin may improve the efficacy of FAC in LABC patients with HER2 overexpression. Copyright 2021by theKoreanCancerAssociation	Breast neoplasms; FAC; Neoadjuvant therapy; Simvastatin	creatine kinase; cyclophosphamide; doxorubicin; epidermal growth factor receptor 2; fluorouracil; simvastatin; antineoplastic agent; cyclophosphamide; doxorubicin; epidermal growth factor receptor 2; ERBB2 protein, human; fluorouracil; simvastatin; adjuvant therapy; adult; advanced breast cancer; aged; alopecia; anemia; Article; blood toxicity; cancer combination chemotherapy; cancer surgery; clinical outcome; constipation; controlled study; creatine kinase blood level; diarrhea; double blind procedure; drug safety; drug tolerability; fatigue; female; gene overexpression; heart ejection fraction; histopathology; human; hypertransaminasemia; immunohistochemistry; Indonesia; invasive lobular breast carcinoma; leukopenia; lung metastasis; major clinical study; modified radical mastectomy; muc	Korean Cancer Association	15982998	33705623	Article	Q1	1668	1870	View
161	Ramlan A.A., Lestari M.I., Banadji Y., Arif S.K.	57195941841;57219312983;57225895278;57189846423;	A national survey of capnography utilization among anaesthesiologists in Indonesia	2021	Trends in Anaesthesia and Critical Care	40			9	13		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109639916&doi=10.1016%2fj.tacc.2021.06.004&partnerID=40&md5=b17959a3c3b317991ee9e2a914ec9547	Department of Anaesthesiology and Intensive Care, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National HospitalJakarta, Indonesia; Department of Anaesthesiology and Intensive Care, Faculty of Medicine Universitas Sriwijaya, Palembang, Indonesia; Department of Anaesthesiology and Intensive Care, Faculty of Medicine Universitas Hasanuddin, Makassar, Indonesia; Indonesian Society of Anaesthesiology and Intensive CareJakarta, Indonesia	Ramlan, A.A., Department of Anaesthesiology and Intensive Care, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National HospitalJakarta, Indonesia, Indonesian Society of Anaesthesiology and Intensive CareJakarta, Indonesia; Lestari, M.I., Department of Anaesthesiology and Intensive Care, Faculty of Medicine Universitas Sriwijaya, Palembang, Indonesia, Indonesian Society of Anaesthesiology and Intensive CareJakarta, Indonesia; Banadji, Y., Indonesian Society of Anaesthesiology and Intensive CareJakarta, Indonesia; Arif, S.K., Department of Anaesthesiology and Intensive Care, Faculty of Medicine Universitas Hasanuddin, Makassar, Indonesia, Indonesian Society of Anaesthesiology and Intensive CareJakarta, Indonesia	Background: Capnography allows health-care providers to continuously monitor the concentration or partial pressure of carbon dioxide in respiratory gas. The American Society of Anaesthesiologists includes end-tidal carbon dioxide monitoring as mandatory monitoring for patients under sedation and anaesthesia. However, capnography is not widely considered for standard patient monitoring in Indonesia. We aim to investigate the utilization of capnography and reasons for lack of use among anaesthesiologists in Indonesia. Methods: An internet-based questionnaire was distributed to participants of an online anaesthesiology national meeting. Data was collected and managed using REDCap electronic data capture tools hosted at Faculty of Medicine Universitas Indonesia. Results: We received 421 respondents' replies nationwide. Replies from anaesthesiologists (n = 367) was used for data analysis. 55.3% (n = 203) reported the availability of capnography in their hospitals. Approximately 77 (21%) of respondents utilize capnography routinely for intraoperative monitoring, 132 (36%) never use capnography. Only 59 (16%) routinely use capnography for intubation confirmation. The utilization of capnography outside the operating theatre was even lower. As many of 249 (67.9%) never use capnography for monitoring during procedural sedation, while 278 (75.8%) do not utilize capnography during patient transfer. Conclusion: The utilization of capnography for intraoperative monitoring is adopted only by half of anaesthesiologists in Indonesia. Outside the operating theatre capnography use is still limited. Capnography as a standard of care should be implemented in all health care institutions in Indonesia. © 2021 Elsevier Ltd	Capnography; Intra-operative monitoring; Standard monitoring	anesthesiologist; Article; capnometry; controlled study; health care quality; health care utilization; human; Indonesia; Internet; intraoperative monitoring; patient safety; patient transport; sedation	Churchill Livingstone	22108440		Article	Q3	213	18603	View
162	Sylvawani M., Setyohadi B., Purnamasari D., Abdullah M., Kurniawan M.R.	57225078775;6504721711;36519537700;7103393434;57192808936;	Comparison of insulin-like growth factor-1 and sclerostin levels between premenopausal women with and without diabetes mellitus	2021	Journal of Taibah University Medical Sciences	16	5		719	723		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109109686&doi=10.1016%2fj.jtumed.2021.05.007&partnerID=40&md5=4f913f9e9865492b0cdd9860adfea935	Division of Rheumatology, Department of Internal Medicine, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia; Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Metabolism and Endocrinology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Sylvawani, M., Division of Rheumatology, Department of Internal Medicine, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia; Setyohadi, B., Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Purnamasari, D., Division of Metabolism and Endocrinology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Abdullah, M., Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Kurniawan, M.R., Division of Rheumatology, Department of Internal Medicine, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia	Objectives: This study assesses the serum levels of insulin-like growth factor-1 (IGF-1) and sclerostin as markers of decreased bone formation in premenopausal women with type 2 diabetes mellitus. Methods: A cross-sectional study was conducted to measure serum levels of IGF-1 and sclerostin in 40 premenopausal women with and without diabetes mellitus using an enzyme-linked immunosorbent assay. The levels of IGF-1 and sclerostin were compared between the groups using the Mann Whitney test and unpaired t-test, respectively. Results: The median IGF-1 serum levels were 40.60 ng/mL and 42.7 ng/mL in the diabetic and non-diabetic groups, respectively, with no significant difference. The serum levels of sclerostin were significantly higher in the diabetic group than in the non-diabetic group (132.1 pg/mL and 96.0 pg/mL, respectively; p < 0.001). Conclusion: The levels of sclerostin were significantly higher in premenopausal women with diabetes mellitus than in the non-diabetic group. Since sclerostin influences the differentiation and maturation of osteoblasts, serum sclerostin might potentially be useful as a marker of decreased bone formation in premenopausal women with diabetes. © 2021 The Authors	Diabetes mellitus; IGF-1; Osteoblasts; Premenopause; Sclerostin	alanine aminotransferase; collagen type 1; creatinine; hemoglobin A1c; insulin; oral antidiabetic agent; sclerostin; somatomedin C; adult; aged; Article; body mass; bone metabolism; cell differentiation; cell maturation; civil servant; comparative study; controlled study; cross-sectional study; diabetic patient; enzyme linked immunosorbent assay; estimated glomerular filtration rate; female; housewife; human; major clinical study; non insulin dependent diabetes mellitus; obesity; ossification; osteoblast; premenopause; private sector; protein blood level	Elsevier B.V.	16583612		Article	Q3	269	15910	View
163	Wahyuningsih R., Adawiyah R., Sjam R., Prihartono J., Ayu Tri Wulandari E., Rozaliyani A., Ronny R., Imran D., Tugiran M., Siagian F.E., Denning D.W.	6507268400;57208658742;23398458200;6602605635;57224979940;57203065912;57224981604;57203976849;57218291154;57205685972;57223404509;	Serious fungal disease incidence and prevalence in Indonesia	2021	Mycoses	64	10		1203	1212	1	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85108784112&doi=10.1111%2fmyc.13304&partnerID=40&md5=5f442b4c8248caad9f19e8d0d684dd18	Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Parasitology, Universitas Kristen Indonesia, School of Medicine, Jakarta, Indonesia; Department of Community Medicine Universitas Indonesia, Faculty of Medicine, Jakarta, Indonesia; Department of Dentistry, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Neurology, Universitas Indonesia, Faculty of Medicine/Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Manchester Fungal Infection Group, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom	Wahyuningsih, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Parasitology, Universitas Kristen Indonesia, School of Medicine, Jakarta, Indonesia; Adawiyah, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Sjam, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Prihartono, J., Department of Community Medicine Universitas Indonesia, Faculty of Medicine, Jakarta, Indonesia; Ayu Tri Wulandari, E., Department of Dentistry, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rozaliyani, A., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Ronny, R., Department of Parasitology, Universitas Kristen Indonesia, School of Medicine, Jakarta, Indonesia; Imran, D., Department of Neurology, Universitas Indonesia, Faculty of Medicine/Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Tugiran, M., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Siagian, F.E., Department of Parasitology, Universitas Kristen Indonesia, School of Medicine, Jakarta, Indonesia; Denning, D.W., Manchester Fungal Infection Group, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, United Kingdom	Background: Indonesia is a tropical country, warm and humid, with numerous environmental fungi. Data on fungal disease burden help policymakers and clinicians. Objectives: We have estimated the incidence and prevalence of serious fungal diseases. Methods: We found all published and unpublished data and estimated the incidence and prevalence of fungal diseases based on populations at risk. HIV data were derived from UNAIDS (2017), pulmonary tuberculosis (PTB) data from 2013–2019, data on chronic pulmonary aspergillosis (CPA) were used to estimate CPA prevalence and likely deaths, COPD data from Hammond (2020), lung cancer incidence was from Globocan 2018, and fungal rhinosinusitis was estimated using community data from India. Results: Overall ~7.7 million Indonesians (2.89%) have a serious fungal infection each year. The annual incidence of cryptococcosis in AIDS was 7,540. Pneumocystis pneumonia incidence was estimated at 15,400 in HIV and an equal number in non-HIV patients. An estimated 1% and 0.2% of new AIDS patients have disseminated histoplasmosis or Talaromyces marneffei infection. The incidence of candidaemia is 26,710. The annual incidence of invasive aspergillosis was estimated at 49,500 and the prevalence of CPA is at 378,700 cases. Allergic bronchopulmonary aspergillosis prevalence in adults is estimated at 336,200, severe asthma with fungal sensitisation at 443,800, and fungal rhinosinusitis at 294,000. Recurrent vulvovaginal candidiasis is estimated at 5 million/year (15–50 years old). The incidence of fungal keratitis around 40,050. Tinea capitis prevalence in schoolchildren about 729,000. Conclusions: Indonesia has a high burden of fungal infections. © 2021 Wiley-VCH GmbH.	aspergillosis; candidaemia; epidemiology	acquired immune deficiency syndrome; adolescent; adult; AIDS patient; allergic bronchopulmonary aspergillosis; Article; atypical mycobacteriosis; candidemia; chronic infection; cryptococcosis; diabetic patient; disease association; disease burden; eye infection; female; fungal sinusitis; histoplasmosis; human; immunocompromised patient; incidence; Indonesia; invasive aspergillosis; keratomycosis; major clinical study; male; mycosis; nonhuman; Pneumocystis pneumonia; prevalence; recurrent infection; respiratory tract disease; severe asthma; skin infection; Talaromyces marneffei; tinea capitis; vagina candidiasis; acquired immune deficiency syndrome; AIDS related complex; candidemia; child; fungus; incidence; lung aspergillosis; middle aged; prevalence; young adult; mycosis; Acquired Immunod	John Wiley and Sons Inc	09337407	33971053	Article	Q1	1130	3649	View
166	Sitohang I.B.S., Sirait S.A.P., Suryanegara J.	56734569200;24482203600;57204535485;	Microneedling in the treatment of atrophic scars: A systematic review of randomised controlled trials	2021	International Wound Journal	18	5		577	585		https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100333569&doi=10.1111%2fiwj.13559&partnerID=40&md5=53a0daf4a5ed46e9fefa3f5918f68c9b	Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia	Sitohang, I.B.S., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Sirait, S.A.P., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Suryanegara, J., Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia	To date, treatment of atrophic acne scars remains a therapeutic challenge for dermatologists, yet there is no standard option on the most effective treatment. Microneedling (MN) is a minimally invasive technology that involves repetitive skin puncture using sterile microneedles to disrupt dermal collagen that connects the scar tissue. Recent studies have demonstrated the potency of MN, such as dermaroller and fractionated microneedle radiofrequency, in the treatment of atrophic scars. The objective of this review is to evaluate systematically the current literature on MN for atrophic acne scars. A systematic search of literature was performed from PubMed, Medline, Cochrane Central, and Google Scholar databases for articles published during the last 20 years. Only randomised controlled trials (RCTs) with full-text version of the manuscript available were included in our study. Nine RCTs were included in this review. All treatment modalities demonstrated consistent results that MN was efficacious in treating atrophic acne scars as a monotherapy or in combination with other treatments. Moreover, no serious adverse effects were reported in all studies after MN treatment. MN is a well-tolerated and effective therapeutic modality in treating atrophic acne scars. Further research is required to validate the efficacy of MN with a larger sample size and lengthy follow-up. © 2021 The Authors. International Wound Journal published by Medicalhelplines.com Inc (3M) and John Wiley & Sons Ltd.	atrophic acne scar; microneedling	acne vulgaris; atrophy; complication; esthetic surgery; human; needle; pathology; randomized controlled trial (topic); scar; treatment outcome; Acne Vulgaris; Atrophy; Cicatrix; Cosmetic Techniques; Humans; Needles; Randomized Controlled Trials as Topic; Treatment Outcome	John Wiley and Sons Inc	17424801	33538106	Article	Q1	867	5385	View

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