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236 |
Lancaster K.E., Mollan K.R., Hanscom B.S., Shook-Sa B.E., Ha T.V., Dumchev K., Djoerban Z., Rose S.M., Latkin C.A., Metzger D.S., Go V.F., Dvoriak S., Reifeis S.A., Piwowar-Manning E.M., Richardson P., Hudgens M.G., Hamilton E.L., Eshleman S.H., Susami H., Chu V.A., Djauzi S., Kiriazova T., Nhan D.T., Burns D.N., Miller W.C., Hoffman I.F. |
55503210000;26659057900;6603650318;55990940100;36988527800;8923601900;23472548200;12544917400;57235096800;35944632400;7102536801;57205192774;57193208279;35783326900;57203639655;6603567044;56450237600;7004740977;57202642757;57195576444;23495847800;55757875500;57317058700;7403171278;7406061778;7006682600; |
Engaging People Who Inject Drugs Living with HIV in Antiretroviral Treatment and Medication for Opioid Use Disorder: Extended Follow-up of HIV Prevention Trials Network (HPTN) 074 |
2021 |
Open Forum Infectious Diseases |
8 |
8 |
ofab281 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118242331&doi=10.1093%2fofid%2fofab281&partnerID=40&md5=6133eea6e10cff9e76240789c9b5b783 |
Division of Epidemiology, College of Public Health, Ohio State University, 1841 Neil Ave, 334 Cunz Hall, Columbus, OH 43210-1351, United States; Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States; Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States; Statistical Center for HIV/AIDS Research and Prevention, Fred Hutchinson Cancer Research Center, Seattle, WA, United States; UNC Vietnam, Hanoi, Viet Nam; Ukrainian Institute on Public Health Policy, Kyiv, Ukraine; Faculty of Medicine, University of Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Science Facilitation Department, FHI 360, Durham, NC, United States; Department of Health Policy and Management, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, United States; HIV Prevention Research Division, Department of Psychiatry, School of Medicine, University of Pennsylvania, Philadelphia, PA, United States; Academy of Labor, Social Relations and Tourism, Kyiv, Ukraine; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, United States; Vietnam Administration of HIV/AIDS Control, Hanoi, Viet Nam; Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States; Division of Infectious Diseases, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States |
Lancaster, K.E., Division of Epidemiology, College of Public Health, Ohio State University, 1841 Neil Ave, 334 Cunz Hall, Columbus, OH 43210-1351, United States; Mollan, K.R., Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States; Hanscom, B.S., Statistical Center for HIV/AIDS Research and Prevention, Fred Hutchinson Cancer Research Center, Seattle, WA, United States; Shook-Sa, B.E., Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States; Ha, T.V., Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States, UNC Vietnam, Hanoi, Viet Nam; Dumchev, K., Ukrainian Institute on Public Health Policy, Kyiv, Ukraine; Djoerban, Z., Faculty of Medicine, University of Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rose, S.M., Science Facilitation Department, FHI 360, Durham, NC, United States; Latkin, C.A., Department of Health Policy and Management, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, United States; Metzger, D.S., HIV Prevention Research Division, Department of Psychiatry, School of Medicine, University of Pennsylvania, Philadelphia, PA, United States; Go, V.F., Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States; Dvoriak, S., Academy of Labor, Social Relations and Tourism, Kyiv, Ukraine; Reifeis, S.A., Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States; Piwowar-Manning, E.M., Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, United States; Richardson, P., Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, United States; Hudgens, M.G., Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States; Hamilton, E.L., Science Facilitation Department, FHI 360, Durham, NC, United States; Eshleman, S.H., Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, United States; Susami, H., Faculty of Medicine, University of Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Chu, V.A., UNC Vietnam, Hanoi, Viet Nam; Djauzi, S., Faculty of Medicine, University of Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Kiriazova, T., Ukrainian Institute on Public Health Policy, Kyiv, Ukraine; Nhan, D.T., Vietnam Administration of HIV/AIDS Control, Hanoi, Viet Nam; Burns, D.N., Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States; Miller, W.C., Division of Epidemiology, College of Public Health, Ohio State University, 1841 Neil Ave, 334 Cunz Hall, Columbus, OH 43210-1351, United States; Hoffman, I.F., Division of Infectious Diseases, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States |
Background: People who inject drugs (PWID) living with HIV experience inadequate access to antiretroviral treatment (ART) and medication for opioid use disorders (MOUD). HPTN 074 showed that an integrated intervention increased ART use and viral suppression over 52 weeks. To examine durability of ART, MOUD, and HIV viral suppression, participants could re-enroll for an extended follow-up period, during which standard-of-care (SOC) participants in need of support were offered the intervention. Methods: Participants were recruited from Ukraine, Indonesia and Vietnam and randomly allocated 3:1 to SOC or intervention. Eligibility criteria included: HIV-positive; active injection drug use; 18-60 years of age; ≥1 HIV-uninfected injection partner; and viral load ≥1,000 copies/mL. Re-enrollment was offered to all available intervention and SOC arm participants, and SOC participants in need of support (off-ART or off-MOUD) were offered the intervention. Results: The intervention continuation group re-enrolled 89 participants, and from week 52 to 104, viral suppression (<40 copies/mL) declined from 41% to 29% (estimated 9.4% decrease per year, 95% CI-17.0%;-1.8%). The in need of support group re-enrolled 94 participants and had increased ART (re-enrollment: 55%, week 26: 69%) and MOUD (re-enrollment: 16%, week 26: 25%) use, and viral suppression (re-enrollment: 40%, week 26: 49%). Conclusions: Viral suppression declined in year 2 for those who initially received the HPTN 074 intervention and improved maintenance support is warranted. Viral suppression and MOUD increased among in need participants who received intervention during the study extension. Continued efforts are needed for widespread implementation of this scalable, integrated intervention. © 2021 The Author(s). |
antiretroviral therapy; HIV infection; injection drug use; methadone/therapeutic use; viral load |
antiretrovirus agent; buprenorphine; methadone; adult; Article; CD4 lymphocyte count; Consolidated Standards of Reporting Trial; controlled study; disease transmission; epidemic; evaluation and follow up; female; health care quality; health education; hepatitis C; human; Human immunodeficiency virus infection; incidence; injection drug user; integrated health care system; intervention study; interview; major clinical study; male; medication compliance; medication for opioid use disorder; medication for opioid use disorder; middle aged; opiate addiction; outcome assessment; paramedical personnel; practice guideline; psychosocial development; randomized controlled trial; telephone interview; viral suppression; virus load; World Health Organization; young adult |
Oxford University Press |
23288957 |
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Article |
Q1 |
1546 |
2161 |
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237 |
Suhaeri M., Kim Y.-M., Yunarti R.T., Song S.-C. |
56183087500;57294592700;56086215900;7403350156; |
Thermoresponsive and suspension forming cyclotriphosphazene conjugate for delivery vehicle of antitumor drug camptothecin |
2021 |
Journal of Drug Delivery Science and Technology |
64 |
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102049 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116958285&doi=10.1016%2fj.jddst.2020.102049&partnerID=40&md5=e52dca3896e5c2ec2892116e880dc19c |
Unit of Education, Research and Training, Universitas Indonesia Hospital, Universitas Indonesia, Depok, 16424, Indonesia; Medical Technology Research Cluster, Indonesia Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta Pusat, 10430, Indonesia; Biomedical Science, Faculty of Medicine, Universitas Indonesia, Jakarta Pusat, 10430, Indonesia; Center for Biomaterials, Biomedical Research Institute, Korea Institute of Science & Technology, Seoul, 02792, South Korea; Inorganic Chemistry Research Laboratory, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Kampus UI Baru, Depok, Jawa Barat 16424, Indonesia; Division of Bio-Medical Science and Technology, KIST School, Korea University of Science and Technology, Seoul, 02792, South Korea |
Suhaeri, M., Unit of Education, Research and Training, Universitas Indonesia Hospital, Universitas Indonesia, Depok, 16424, Indonesia, Medical Technology Research Cluster, Indonesia Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta Pusat, 10430, Indonesia, Biomedical Science, Faculty of Medicine, Universitas Indonesia, Jakarta Pusat, 10430, Indonesia; Kim, Y.-M., Center for Biomaterials, Biomedical Research Institute, Korea Institute of Science & Technology, Seoul, 02792, South Korea, Division of Bio-Medical Science and Technology, KIST School, Korea University of Science and Technology, Seoul, 02792, South Korea; Yunarti, R.T., Inorganic Chemistry Research Laboratory, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Kampus UI Baru, Depok, Jawa Barat 16424, Indonesia; Song, S.-C., Center for Biomaterials, Biomedical Research Institute, Korea Institute of Science & Technology, Seoul, 02792, South Korea, Division of Bio-Medical Science and Technology, KIST School, Korea University of Science and Technology, Seoul, 02792, South Korea |
Camptothecin (CPT) has been used as antitumor drug against a wide range of cancer cells. However, its clinical application is greatly hindered by insolubility and instability issues under physiological condition. Therefore, an appropriate CPT administration technique directed for living system is greatly anticipated. In this study, a delivery method for CPT in the form of thermoresponsive system was prescribed. A conjugate of cyclotriphosphazene and CPT was synthesized by substituting hexachlorocyclotriphosphazene with sodium salt of methoxy-poly (ethylene glycol) (Mw = 350), 20-O-trifluoroglycinylCPT, and isoleucine ethyl ester, respectively. The resulting cyclotriphosphazene-CPT was characterized via multinuclear (1H and 31P) NMR as well as FT-IR. The current conjugate showed temperature induced phase transition (solution to suspension) with a lower critical solution temperature at 31 °C. Our result indicated that the stability issue related to the use of CPT in aqueous solution could be handled by acylation at 20-OH moiety. Additionally, antitumor activity of cyclotriphosphazene-CPT, to some extent, was found to be more profound than that of CPT alone as evaluated against human colorectal cancer cell HCT-116. Altogether, the current cyclotriphosphazene-CPT conjugate might offer a facile method in delivering CPT as a minimally invasive system for treating cancer. © 2020 Elsevier B.V. |
Antitumor; Camptothecin; Conjugate; Cyclotriphosphazene; Drug delivery; Thermoresponsive |
camptothecin; hexachlorocyclotriphosphazene; isoleucine; macrogol; polymer; sodium; unclassified drug; antineoplastic activity; Article; critical solution temperature; drug conjugation; drug delivery system; drug structure; drug synthesis; Fourier transform infrared spectroscopy; HCT 116 cell line; human; human cell; phase transition; phosphorus nuclear magnetic resonance; proton nuclear magnetic resonance; temperature |
Editions de Sante |
17732247 |
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Article |
Q2 |
663 |
7562 |
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238 |
Heltty H., Sitorus R., Nusdwinuringtyas N., Martha E. |
57262112500;57194329674;56608215500;55841280100; |
Effect of Self-Regulation and Social Support Intervention on the Life Quality in Patients with Post-Stroke Urinary Incontinence |
2021 |
Korean Journal of Adult Nursing |
33 |
4 |
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399 |
405 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115059615&doi=10.7475%2fkjan.2021.33.4.399&partnerID=40&md5=167ab64de29a0974bb46e8b9444819a3 |
Doctoral Student of Nursing Faculty, Universitas Indonesia, Depok Indonesia, Jl. Prof. Dr. Bahder Djohan, Kampus UI Depok Jawa Barat, Indonesia; Professor of Nursing, Faculty of Nursing, Universitas Indonesia, Jl. Prof. Dr. Bahder Djohan, Kampus UI Depok Jawa Barat, Indonesia; Associate Professor Ph.D, Faculty of Medicine, Universitas Indonesia, Depok, Indonesia; Associate Professor Ph.D M.Kes (health), Faculty of Public Health, Universitas Indonesia, Depok, Indonesia |
Heltty, H., Doctoral Student of Nursing Faculty, Universitas Indonesia, Depok Indonesia, Jl. Prof. Dr. Bahder Djohan, Kampus UI Depok Jawa Barat, Indonesia; Sitorus, R., Professor of Nursing, Faculty of Nursing, Universitas Indonesia, Jl. Prof. Dr. Bahder Djohan, Kampus UI Depok Jawa Barat, Indonesia; Nusdwinuringtyas, N., Associate Professor Ph.D, Faculty of Medicine, Universitas Indonesia, Depok, Indonesia; Martha, E., Associate Professor Ph.D M.Kes (health), Faculty of Public Health, Universitas Indonesia, Depok, Indonesia |
Purpose: This study aimed to determine the effect of self-regulation and social support on post-stroke patients experiencing urinary incontinence. Methods: This quasi-experimental study was conducted in Kota Kendari, Indonesia. Through consecutive sampling, 53 participants were selected: 26 in the experimental groups and 27 in the control group, studied over a period of four weeks. The self-regulation intervention included education about properly following recommended exercises to overcome urinary incontinence, focusing on goals, being optimistic, and having emotional control. The social support intervention included the provision of family and peer support during patient care. Differences in participants' quality of life was measured at three different stages during the study, using the Incontinence Quality of Life instrument. Data were analyzed using descriptive statistics, independent t-tests, and repeated measures ANOVA. Results: There was homogeneity of variance in both groups. Significant differences in quality of life were seen in the second and third measurements (p<.001). The interventions improved patients' quality of life by 6.43 times at 4 weeks, and 13 times at 8 weeks. Conclusion: Self-regulation and social support played an important role in improving the quality of life of post-stroke urinary incontinence patients. Further studies with longer intervention periods are required to validate our results and contribute to better patient experiences. © 2021. All Rights Reserved. |
Emotional regulation; Quality of life; Social support; Stroke; Urinary incontinence |
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Korean Society of Adult Nursing |
12254886 |
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Article |
Q3 |
253 |
16577 |
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239 |
Sobri F.B., Bachtiar A., Panigoro S.S., Rahmaania J.C., Yuswar P.W., Krisnuhoni E., Tandiari N. |
57217500979;56683183900;56790104300;57252632900;57253490900;35310982200;57252633000; |
Strategy for diagnosing breast cancer in Indonesia during the COVID-19 pandemic: Switching to ultrasound-guided percutaneous core needle biopsy |
2021 |
Kesmas |
16 |
3 |
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151 |
157 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114650507&doi=10.21109%2fkesmas.v16i3.4359&partnerID=40&md5=dbf4756507a59d7c2f87cc7eb69f6787 |
Faculty of Public Health, Universitas Indonesia, Depok, Indonesia; Department of Surgical Oncology, Metropolitan Medical Centre Hospital, Jakarta, Indonesia; Department of Health Policy and Administration, Faculty of Public Health, Universitas Indonesia, Depok, Indonesia; Department of Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Surgery, Metropolitan Medical Centre Hospital, Jakarta, Indonesia; Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Pathology, Metropolitan Medical Centre Hospital, Jakarta, Indonesia; Department of Radiology, Metropolitan Medical Centre Hospital, Jakarta, Indonesia |
Sobri, F.B., Faculty of Public Health, Universitas Indonesia, Depok, Indonesia, Department of Surgical Oncology, Metropolitan Medical Centre Hospital, Jakarta, Indonesia; Bachtiar, A., Department of Health Policy and Administration, Faculty of Public Health, Universitas Indonesia, Depok, Indonesia; Panigoro, S.S., Department of Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Rahmaania, J.C., Department of Surgery, Metropolitan Medical Centre Hospital, Jakarta, Indonesia; Yuswar, P.W., Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Krisnuhoni, E., Department of Pathology, Metropolitan Medical Centre Hospital, Jakarta, Indonesia; Tandiari, N., Department of Radiology, Metropolitan Medical Centre Hospital, Jakarta, Indonesia |
In this era of COVID-19, suspected breast cancer patients experience delay in diagnosis due to the fear of contracting the virus and reduction of non-COVID-19 health services. Furthermore, it may lead to potential increase in the incidence of advanced cancers in the future. Ultrasound-guided (US-guided) percutaneous core needle biopsy (CNB) is a great option for the diagnosis of cancer but it is poorly utilized. This study aimed to prove that the US-guided CNB is accurate when performed in a local setting and a potential solution for diagnosing breast cancer patients in this pandemic. In addition, it was a single health center cross-sectional study, and the participants were all breast cancer patients that had US-guided CNB from 2013-2019. The pathology results from US-guided CNB were compared to specimens from post-CNB surgeries. The data were collected from medical records and the immunohistochemistry (IHC) examinations were carried out for malignancy. There were 163 patients who were included in this study, 86 had malignancies and 77 had benign tumor reported in their CNB results. The US-guided CNB had 100% sensitivity and specificity compared to surgery. With its lower cost, time usage, and patient exposure to the hospital environment, US-guided CNB should replace open surgery biopsy for diagnosing suspicious breast cancers during the pandemic in Indonesia. Copyright © 2021, Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal). |
Breast cancer; Core needle biopsy; COVID-19; Health cost; Resources |
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Universitas Indonesia, Faculty of public health |
19077505 |
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Article |
Q4 |
146 |
23606 |
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240 |
Nathania M., Sunardi D. |
57245860300;57192075078; |
The importance of balanced nutrition to fortify the immune system during the covid-19 outbreak [La importancia de una nutrición equilibrada para aumentar el sistema inmunológico durante el brote de covid-19] |
2021 |
Revista Chilena de Nutricion |
48 |
4 |
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620 |
629 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114246311&doi=10.4067%2fS0717-75182021000400620&partnerID=40&md5=c999acae5c75b659b516d0fbb8b1815b |
Department of Nutrition, Faculty of Medicine, University of Indonesia-Ciptomangunkusumo National Hospital, Jakarta Pusat, 10430, Indonesia |
Nathania, M., Department of Nutrition, Faculty of Medicine, University of Indonesia-Ciptomangunkusumo National Hospital, Jakarta Pusat, 10430, Indonesia; Sunardi, D., Department of Nutrition, Faculty of Medicine, University of Indonesia-Ciptomangunkusumo National Hospital, Jakarta Pusat, 10430, Indonesia |
COVID-19, first reported in December 2019 in Wuhan, China, quickly spread worldwide and was announced as a pandemic in March 2020. As symptoms and outcomes are varied, the elderly and those who have at least one comorbidity (diabetes, cardiovascular disorders or other chronic diseases) are considered to be at high risk and are generally have lower immunity. An optimal immune system is critical for survival, as it protects the body against infectious agents. Nutrition is an essential factor in the immune system, contributing to components in physical barriers, biochemical, innate and adaptive immunity. Research advances show that nutritional deficiencies, namely the inadequacy of energy, macronutrients and micronutrients, affect the immune system and increase infection risk. The following discussion explains the comprehensive role of nutrition in the immune system, nutrition recommendations that can be used as precautions and the need for supplementation during this outbreak. © 2021, Sociedad Chilena de Nutricion Bromatologia y Toxilogica. All rights reserved. |
COVID-19; Immune; Nutrition; Pandemic; Supplementation |
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Sociedad Chilena de Nutricion Bromatologia y Toxilogica |
07177518 |
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Review |
Q4 |
182 |
20570 |
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242 |
Bintoro D.A., Nareswari I. |
57237633100;57194336586; |
The Role of Electroacupuncture in the Regulation of Appetite-Controlling Hormone and Inflammatory Response in Obesity |
2021 |
Medical Acupuncture |
33 |
4 |
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264 |
268 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113821541&doi=10.1089%2facu.2020.1500&partnerID=40&md5=b4a919cddf828d9f0978d90ea651ac42 |
Department of Medical Acupuncture, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central Public Hospital, Central Jakarta, Jakarta, Indonesia |
Bintoro, D.A., Department of Medical Acupuncture, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central Public Hospital, Central Jakarta, Jakarta, Indonesia; Nareswari, I., Department of Medical Acupuncture, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central Public Hospital, Central Jakarta, Jakarta, Indonesia |
Objective: Obesity, a condition with serious complications, needs special attention. It is a complex and multifactorial problem and regulation of calorie balance involving various humoral and central factors is the main key for managing obesity. In addition, there is an increase in various proinflammatory cytokines and an increase in oxidative stress. There is a need to discover a useful therapy for obesity management. The goal of this review was to examine the literature on electroacupuncture (EA) as a potential therapy. Methods: This review explores the literature on EA, which has proven to be effective for inducing weight loss in experimental human and animal studies. Both continuous and dense-disperse EA waves have their own roles in hormone regulation of obesity using ST 25, CV 9, CV 12, CV 4, SP 6, ST 36, and ST 44; this is discussed the associated mechanism related to this is through suppression of various orexigenic peptides, enhancement of anorexigenic peptides, suppression of inflammatory factors, and improvement in the balance of pro-oxidants and antioxidants. Conclusions: The absence of another definitive therapy for obesity and EA's minimal side-effects make it a potential therapy for managing obesity. © Copyright 2021, Mary Ann Liebert, Inc., publishers 2021. |
electroacupuncture; inflammation; obesity; oxidative stress |
ghrelin; acupuncture; appetite; body weight loss; electroacupuncture; food intake; human; inflammation; nonhuman; obesity; oxidative stress; pathophysiology; Review |
Mary Ann Liebert Inc. |
19336586 |
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Review |
Q2 |
281 |
15498 |
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243 |
Nareswari I., Lestari S.W., Notonegoro C. |
57194336586;55980501200;57224857889; |
Acupuncture Therapy for Severe Oligoasthenoteratozoospermia |
2021 |
Medical Acupuncture |
33 |
4 |
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302 |
305 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113775889&doi=10.1089%2facu.2020.1513&partnerID=40&md5=04fcbc629e9b71da58c0b69ee5116b7c |
Department of Medical Acupuncture, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Anna Hospital, Pekayon, Indonesia; Medical Acupuncture Specialist Program, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Medical Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Nareswari, I., Department of Medical Acupuncture, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Anna Hospital, Pekayon, Indonesia, Medical Acupuncture Specialist Program, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Lestari, S.W., Anna Hospital, Pekayon, Indonesia, Department of Medical Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Notonegoro, C., Department of Medical Acupuncture, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia, Medical Acupuncture Specialist Program, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Background: Infertility affects ∼15%-20% of couples. Of the 16.7% infertility rate reported based on Word Health Organisation questionnaire data, 6.4% of cases are associated with male factors. Male infertility can result from abnormal semen parameters; oligoasthenoteratozoospermia (OAT) is the most common diagnosis. Acupuncture is an ancient method that has been used for centuries to treat and prevent various conditions. In modern medicine, it is gaining popularity as a complementary infertility therapy. Case: A 41-year-old male presented to the Medical Acupuncture Department of Dr. Cipto Mangunkusumo Hospital (in Jakarta, Indonesia) because he wanted to have a child. His semen was analyzed, and he was diagnosed with severe OAT. Manual acupuncture therapy was performed at CV 3, CV 4, CV 5, CV 6, CV 7, ST 29, SP 6, SP 3, ST 36, and KI 3, alternating with KI 7 5 days per week and at LR 8 once per week, for a total of 28 sessions. Results: Semen analysis after 2 series of manual acupuncture treatments revealed improvement, especially in sperm motility, from 25% to 33% and then to 67% after the first and second serial therapies, respectively, changing the diagnosis from severe OAT to severe oligoteratozoospermia. Conclusions: Manual acupuncture combined with medication improves male fertility, especially sperm motility. © Copyright 2021, Mary Ann Liebert, Inc., publishers 2021. |
Acupuncture; Male Infertility; Oligoasthenoteratozoospermia |
alpha tocopherol; ascorbic acid; beta carotene; clomifene citrate; glutathione; lycopene; mineral; selenium; ubidecarenone; zinc; acupuncture; acupuncture point; adult; Article; case report; clinical article; follow up; high fiber diet; human; Indonesia; male; male infertility; oligoasthenoteratozoospermia; semen analysis; spermatozoon motility; Tribulus terrestris |
Mary Ann Liebert Inc. |
19336586 |
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Article |
Q2 |
281 |
15498 |
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244 |
Djaali W. |
57212479564; |
How Do You Treat Non-Insulin Dependent Diabetes in Your Practice? |
2021 |
Medical Acupuncture |
33 |
4 |
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306 |
308 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113733355&doi=10.1089%2facu.2021.29182.cpl&partnerID=40&md5=d5215d516a5077a554bb640392817b63 |
Universitas Negeri Jakarta Jl. Rawamangun Muka East Jakarta, Jakarta, 13220, Indonesia; Department of Medical Acupuncture, Faculty of Medicine, Universitas Indonesia, RSUPN Dr. Cipto Mangunkusumo Central Jakarta, Jakarta, Indonesia |
Djaali, W., Universitas Negeri Jakarta Jl. Rawamangun Muka East Jakarta, Jakarta, 13220, Indonesia, Department of Medical Acupuncture, Faculty of Medicine, Universitas Indonesia, RSUPN Dr. Cipto Mangunkusumo Central Jakarta, Jakarta, Indonesia |
[No abstract available] |
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hemoglobin A1c; acupuncture; acupuncture point; adult; Article; case report; clinical article; evaluation study; evidence based practice; fatigue; glucose blood level; histology; human; male; middle aged; non insulin dependent diabetes mellitus; Research Diagnostic Criteria; signal transduction; somnolence; treatment planning |
Mary Ann Liebert Inc. |
19336586 |
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Article |
Q2 |
281 |
15498 |
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246 |
Ichwan S., Ningsih H.L., Aman R.A., Tandian D., Ashari S., Gunawan K., Nugroho S.W. |
57192906639;57226696258;36848942500;57192891173;57195942105;57195935319;57460519700; |
O6-methylguanine-dna methyltransferase (Mgmt) promoter methylation status of high-grade and low-grade gliomas |
2021 |
Bali Medical Journal |
10 |
2 |
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644 |
647 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112380308&doi=10.15562%2fbmj.v10i2.2316&partnerID=40&md5=c8e8a17690a11b9cc2f1729ff7a40de8 |
Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia |
Ichwan, S., Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Ningsih, H.L., Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Aman, R.A., Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Tandian, D., Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Ashari, S., Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Gunawan, K., Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Nugroho, S.W., Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia |
Background: O6-methylguanine-DNA methyltransferase (MGMT) is a DNA-repair enzyme that correlates with tumor resistance mechanism to chemotherapy. Methylation of the MGMT promoter inhibits the cells from producing MGMT and is useful to predict chemotherapy’s effectiveness with alkylating agents. This study aims to evaluate the MGMT promoter methylation of low-grade and high-grade glioma in the Neurosurgery Department of Cipto Mangunkusumo National General Hospital. Methods: We evaluated MGMT promoter methylation status using methylation-specific polymerase chain reaction in low and high-grade glioma patients who underwent surgical resection in the Neurosurgery Department of Cipto Mangunkusomo Hospital Jakarta. The result then correlated with age, sex, Karnofsky Performance Scale (KPS), and glioma grading. Data were analyzed using SPSS version 20 for Windows. Results: MGMT promoter methylation was observed more often in patients diagnosed with age more than 40 years old than in patients less than 40 years old (85.7% vs. 50.0%), also more in men than women (77.7% vs. 50.0%). In patients with KPS more than 70 and KPS 70 or less, methylation of MGMT promoter was observed in 70.0% and 57.1%, respectively. Based on tumor grading, MGMT promoter methylation was observed more often in low-grade gliomas (WHO grade II) than high-grade gliomas (WHO grade II and IV) (85.7% vs. 50.0%). There was no significant relationship between gender, age, KPS, malignancy degree, and Overall Survival (OS) to the MGMT promoter methylation (p>0.05). Conclusion: MGMT promoter methylation was observed less in the higher grade of tumors (grade IV), lower KPS, younger age at the time of diagnosis, and female patients, although the differences were not statistically significant. MGMT promoter methylation was observed more often in gliomas with oligodendroglioma components. © 2021, Sanglah General Hospital. All rights reserved. |
High-grade glioma; Low-grade glioma; Methylation; MGMT; Promoter |
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Sanglah General Hospital |
20891180 |
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Isa M.M., Thayeb A., Meildi M., Hutagalung M.B.Z. |
57218775163;57219243978;57226686555;57210153230; |
Complete tubular duplication of colon presenting as rectovestibular fistula: A case report |
2021 |
Bali Medical Journal |
10 |
2 |
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526 |
528 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112379837&doi=10.15562%2fbmj.v10i2.2386&partnerID=40&md5=d43bedd4e25f7ac4c1c60fafddc9df64 |
Pediatric Surgery Division, Department of Surgery, Faculty of Medicine, Universitas Syiah Kuala/Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia; Pediatric Surgery Division, Department of Surgery, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Surgery, Faculty of Medicine, Universitas Syiah Kuala/Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia |
Isa, M.M., Pediatric Surgery Division, Department of Surgery, Faculty of Medicine, Universitas Syiah Kuala/Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia; Thayeb, A., Pediatric Surgery Division, Department of Surgery, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Meildi, M., Department of Surgery, Faculty of Medicine, Universitas Syiah Kuala/Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia; Hutagalung, M.B.Z., Department of Surgery, Faculty of Medicine, Universitas Syiah Kuala/Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia |
Background: Duplication of the gastrointestinal tract is a rare congenital disorder in pediatric patients. Complete resection in case of a total tubular duplication that requires total or subtotal colectomy is undesirable in children. Case Presentation: This case presented a simple surgical technique for treating complete colonic duplication without colonic resection. A 2 months old female baby with abdominal distention and stool complaint came out from her vaginal vestibular and normal anus. A digital rectal exam showed a palpable mass in the posterior region. Abdominal CT Scan showed a rounded mass with size 2x2 cm in the left posterolateral of rectum region. The initial diagnosis was suspected sacrococcygeal tumor type 4 with rectovestibular fistula. Intraoperative findings showed duplication of the caecum, appendix, total colon (ascending to sigmoid) and rectum (one directed to the vagina and the other to anus). The ileostomy was done 20 cm from the ileocaecal junction as a temporary treatment to relieving distention with definitive repair planned in the following months. The second stage repair was performed after 1-year-old with posterosagital anorectoplasty followed by distal separation of the duplicated colon using a 12 cm linear stapler. For this case, the third stage repair was done one year after the previous surgery to close the remaining ileostomy. The patient’s outcome showed good results with normal defecating function and no complication. Conclusion: Complete tubular duplication is a rare case without specific clinical symptoms, but the assessment of the diagnosis can be assisted by radiology such as abdominal CT and barium enema. We hope this article could illustrate management for complete tubular duplication of colon presenting as rectovestibular fistula, thus reflect how important clinical judgment and initial diagnostic in our health care system. © 2021, Sanglah General Hospital. All rights reserved. |
Colon Duplication; Repair; Surgery |
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Sanglah General Hospital |
20891180 |
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