No records
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192 |
Legiawati L., Raissa, Widaty S., Kekalih A., Dorthy I., Lubis F. |
57202804484;57240272100;57208261546;55633562200;57297917600;57239954700; |
Prevalence of hair disorders and their related factors among adolescent students in public boarding school, west java, indonesia |
2021 |
Pakistan Paediatric Journal |
45 |
3 |
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357 |
362 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85117179598&partnerID=40&md5=44d7f353baa4a714054391e217fb7893 |
Department of Dermatology and Venereology Aria Kekalih Department of Community Medicine Faculty of Medicine, Universitas Indonesia dr. Cipto Mangunkusumo National Central General Hospital, Central Jakarta, Indonesia |
Legiawati, L., Department of Dermatology and Venereology Aria Kekalih Department of Community Medicine Faculty of Medicine, Universitas Indonesia dr. Cipto Mangunkusumo National Central General Hospital, Central Jakarta, Indonesia; Raissa, Department of Dermatology and Venereology Aria Kekalih Department of Community Medicine Faculty of Medicine, Universitas Indonesia dr. Cipto Mangunkusumo National Central General Hospital, Central Jakarta, Indonesia; Widaty, S., Department of Dermatology and Venereology Aria Kekalih Department of Community Medicine Faculty of Medicine, Universitas Indonesia dr. Cipto Mangunkusumo National Central General Hospital, Central Jakarta, Indonesia; Kekalih, A., Department of Dermatology and Venereology Aria Kekalih Department of Community Medicine Faculty of Medicine, Universitas Indonesia dr. Cipto Mangunkusumo National Central General Hospital, Central Jakarta, Indonesia; Dorthy, I., Department of Dermatology and Venereology Aria Kekalih Department of Community Medicine Faculty of Medicine, Universitas Indonesia dr. Cipto Mangunkusumo National Central General Hospital, Central Jakarta, Indonesia; Lubis, F., Department of Dermatology and Venereology Aria Kekalih Department of Community Medicine Faculty of Medicine, Universitas Indonesia dr. Cipto Mangunkusumo National Central General Hospital, Central Jakarta, Indonesia |
Objective: Hair disorders in children and teenagers are abnormalities that often appear and can cause complex clinical problems. It can be congenital or acquired from the environment. The aim was to observe the prevalence of hair disorders and their related factors in specific population, also to recognize their dermoscopic description. Study Design: Descriptive cross-sectional study Place and Duration of Study: The research was conducted from September 2018 to February 2019 in one public boarding school (PBS), West Java. Material and Methods: Participants were 127 students consisting of 85 boys and 42 girls, with age ranging from 11-15 years. Diagnosis was determined by history taking, physical and dermoscopic examination. Results: The most common hair disorder was pediculosis capitis, identified in 86 students (67.7%). All girl subjects were diagnosed with it, while in boy group there were 44 out of 85 students. When the pediculosis capitis group was compared with no hair disease group, the statistically significant factors were gender, frequency of washing towel and habit of using towel. Other kind of hair disorders discovered were scarring alopecia (3.2%), seborrheic dermatitis (0.8%), and nevus sebaceous (0.8%). Conclusion: Very high prevalence of pediculosis capitis in this PBS is influenced by high occupancy in one bedroom, also poor hygiene, such as longer frequency of changing towel, and habit of sharing prayer dresses. These results should be an important note for public health officer to raise awareness about this case. © 2021, Pakistan Pediatric Journal. All rights reserved. |
Adolescent; Dermoscopy; Hair diseases; Lice infestations; Prevalence |
adolescent; alopecia; Article; awareness; body mass; child; cross-sectional study; epiluminescence microscopy; female; hair disease; hair loss; health care personnel; human; hygiene; Indonesia; major clinical study; male; pediculosis capitis; Pediculus humanus capitis; prevalence; scalp pruritus; school child; sebaceous nevus; seborrheic dermatitis; student |
Pakistan Pediatric Journal |
03044904 |
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Article |
Q4 |
122 |
26784 |
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195 |
Habiburrahman M., Lesmana E., Harmen F., Gratia N., Mirtha L.T. |
57320844200;57208440285;57288593800;57288763400;57193201450; |
The impact of sleep deprivation on work performance towards night-shift healthcare workers: An evidence-based case report |
2021 |
Acta Medica Philippina |
55 |
6 |
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650 |
664 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116676334&doi=10.47895%2fAMP.V55I6.3157&partnerID=40&md5=279c9c6f812ba7d9e6cf09363847268d |
Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Hospital of Universitas Indonesia, Depok, Indonesia |
Habiburrahman, M., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Lesmana, E., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Harmen, F., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Gratia, N., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Mirtha, L.T., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Hospital of Universitas Indonesia, Depok, Indonesia |
Background. Poor sleep and excessive fatigue among workers can reduce well-being and physical fitness. However, not many studies have mentioned how sleeping deprivation among night-shift healthcare workers impacted their work performance in multiple aspects. Method. We conducted an evidence-based case report (EBCR) of a night shift nurse who was worried about the impact of her sleep deprivation on her work performance in the future due to prior history of needle-stick injuries. We aimed to determine whether sleeping deprivation caused by regular night shifts leads to decreased work performance among night-shift healthcare workers by formulating a clinical question. Evidence was searched systematically using five major journal databases (Proquest, EBSCO-Host, PubMed, ScienceDirect, and Cochrane) and was assessed thoroughly using inclusion and exclusion criteria. Results. Eleven eligible studies were obtained with a medium level of evidence (III-IV), three systematic reviews with meta-analyses (SR-MA), three SR without MA, and five observational studies. All of them were analyzed and critically appraised using Oxford Evidence-Based Medicine and Joanna Briggs Institute tools. We found that reduced quantity and quality of sleep impacted all dimensions of work performance among healthcare professionals, be it in task performance (e.g., skill proficiency), contextual performance (e.g., communication skill and mental health issues), and patient and health worker safety (accident and medication error). It could also encourage counterproductive work behavior, such as absenteeism. Furthermore, sleep deprivation changes circadian rhythms, causing decreased information processing and affective recognition functions in some vital brain areas, ultimately affecting several work dimensions. Conclusion. In conclusion, stakeholders need to adjust proper shift scheduling for health care workers, practice sleep hygiene, maintain physical fitness, and consume nutritional food, positively correlated to health and productivity. © 2021 University of the Philippines Manila. All rights reserved. |
Evidence-based medicine; Healthcare worker; Night shift; Sleep deprivation; Work performance |
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University of the Philippines Manila |
00016071 |
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Article |
Q4 |
128 |
25603 |
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196 |
Alie I.R., Andriantoro H., Timan I.S., Sulistomo A.W., Illyas E.I., Mansyur M. |
57288933200;55037171500;6602793366;57024018500;57288423500;37085506800; |
Potency biomarker effect of endothelial microparticles (emps) for early prediction of cardiovascular risk in shift worker nurses |
2021 |
Acta Medica Philippina |
55 |
6 |
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616 |
620 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85116671512&doi=10.47895%2fAMP.V55I6.3142&partnerID=40&md5=10ceaf9c58aabc0ce93083d831644fe1 |
Program of Universitas Indonesia; Department of Cardiology and Vascular Faculty of Medicine, Universitas Indonesia; Department of Pathology Clinic, Faculty of Medicine, Universitas Indonesia; Department of Community Medicine, Faculty of Medicine, Universitas Indonesia; Department of Physiology, Faculty of Medicine, Universitas Indonesia |
Alie, I.R., Program of Universitas Indonesia; Andriantoro, H., Department of Cardiology and Vascular Faculty of Medicine, Universitas Indonesia; Timan, I.S., Department of Pathology Clinic, Faculty of Medicine, Universitas Indonesia; Sulistomo, A.W., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia; Illyas, E.I., Department of Physiology, Faculty of Medicine, Universitas Indonesia; Mansyur, M., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia |
Objectives. Shift work results in changing worker's behavior, food, and sleep patterns, which can cause circadian rhythm disturbance, which is a cardiovascular risk. Until now, a biomarker of early prediction of cardiovascular risk on shift workers is still not developed. This study aimed to assess the cardiovascular risk of shift worker nurses by detecting endothelial microparticles (EMPs). Methods. This longitudinal study compared six shift nurses and five non-shift nurses by measuring the EMPs using antigen CD31+ flow cytometry. All met the inclusion criteria consisting of 28 blood samples followed in one week shift. Results. EMPs among non-shift nurses were below 200 μL. However, shift nurses' EMPs increased above 200 μL with Man-Whitney U p = 0.000 on days 4 and 7 following a one shift per week schedule. Conclusion. There was an increase in shift workers' endothelial microparticles (EMP) which was a sign of cardiovascular risk. © 2021 University of the Philippines Manila. All rights reserved. |
Cardiovascular risk; CD31+; Endothelial microparticles (EMPs); Nurse; Shift work |
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University of the Philippines Manila |
00016071 |
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Article |
Q4 |
128 |
25603 |
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197 |
Permata T.B.M., Sato H., Gu W., Kakoti S., Uchihara Y., Yoshimatsu Y., Sato I., Kato R., Yamauchi M., Suzuki K., Oike T., Tsushima Y., Gondhowiardjo S., Ohno T., Yasuhara T., Shibata A. |
57197808751;55697961900;57211574572;57197814645;57221723636;57284438600;57285097100;57204087445;8307897300;57376271900;36453136000;57284002500;6508327402;35395665700;56562637100;8323572900; |
High linear energy transfer carbon-ion irradiation upregulates PD-L1 expression more significantly than X-rays in human osteosarcoma U2OS cells |
2021 |
Journal of Radiation Research |
62 |
5 |
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773 |
781 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115918333&doi=10.1093%2fjrr%2frrab050&partnerID=40&md5=a1550b83230aa8ab90277d2716e9a556 |
Department of Radiation Oncology, Gunma University, Gunma, Maebashi, 371-8511, Japan; Department of Radiation Oncology, Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia; Gunma University Heavy IonMedical Center, Gunma, Maebashi, 371-8511, Japan; Gunma University Initiative for Advanced Research (GIAR), Gunma University, Gunma, Maebashi, 371-8511, Japan; Department of Diagnostic Radiology and Nuclear Medicine, Gunma University Graduate School OfMedicine, Gunma, Maebashi, 371-8511, Japan; Laboratory of Molecular Radiology, Center for Disease Biology and Integrative Medicine, Graduate School OfMedicine, The University OfTokyo, Bunkyo-ku, Tokyo, 113-8655, Japan; Department of Radiation Biology and Protection, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, 852-8523, Japan; Department of Radiation Medical Science, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, 852-8523, Japan |
Permata, T.B.M., Department of Radiation Oncology, Gunma University, Gunma, Maebashi, 371-8511, Japan, Department of Radiation Oncology, Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia; Sato, H., Department of Radiation Oncology, Gunma University, Gunma, Maebashi, 371-8511, Japan, Gunma University Heavy IonMedical Center, Gunma, Maebashi, 371-8511, Japan; Gu, W., Gunma University Initiative for Advanced Research (GIAR), Gunma University, Gunma, Maebashi, 371-8511, Japan, Department of Diagnostic Radiology and Nuclear Medicine, Gunma University Graduate School OfMedicine, Gunma, Maebashi, 371-8511, Japan; Kakoti, S., Department of Radiation Oncology, Gunma University, Gunma, Maebashi, 371-8511, Japan, Gunma University Initiative for Advanced Research (GIAR), Gunma University, Gunma, Maebashi, 371-8511, Japan; Uchihara, Y., Gunma University Initiative for Advanced Research (GIAR), Gunma University, Gunma, Maebashi, 371-8511, Japan; Yoshimatsu, Y., Gunma University Initiative for Advanced Research (GIAR), Gunma University, Gunma, Maebashi, 371-8511, Japan, Department of Diagnostic Radiology and Nuclear Medicine, Gunma University Graduate School OfMedicine, Gunma, Maebashi, 371-8511, Japan; Sato, I., Gunma University Initiative for Advanced Research (GIAR), Gunma University, Gunma, Maebashi, 371-8511, Japan; Kato, R., Laboratory of Molecular Radiology, Center for Disease Biology and Integrative Medicine, Graduate School OfMedicine, The University OfTokyo, Bunkyo-ku, Tokyo, 113-8655, Japan; Yamauchi, M., Department of Radiation Biology and Protection, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, 852-8523, Japan; Suzuki, K., Department of Radiation Medical Science, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, 852-8523, Japan; Oike, T., Department of Radiation Oncology, Gunma University, Gunma, Maebashi, 371-8511, Japan; Tsushima, Y., Gunma University Initiative for Advanced Research (GIAR), Gunma University, Gunma, Maebashi, 371-8511, Japan; Gondhowiardjo, S., Department of Radiation Oncology, Faculty of Medicine Universitas Indonesia - Dr. Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia; Ohno, T., Department of Radiation Oncology, Gunma University, Gunma, Maebashi, 371-8511, Japan, Gunma University Heavy IonMedical Center, Gunma, Maebashi, 371-8511, Japan; Yasuhara, T., Laboratory of Molecular Radiology, Center for Disease Biology and Integrative Medicine, Graduate School OfMedicine, The University OfTokyo, Bunkyo-ku, Tokyo, 113-8655, Japan; Shibata, A., Gunma University Initiative for Advanced Research (GIAR), Gunma University, Gunma, Maebashi, 371-8511, Japan |
Programmed death ligand 1 (PD-L1) expression on the surface of cancer cells affects the efficacy of anti-PD-1/PD-L1 immune checkpoint therapy. However, the mechanism underlying PD-L1 expression in cancer cells is not fully understood, particularly after ionizing radiation (IR). Here, we examined the impact of high linear energy transfer (LET) carbon-ion irradiation on the expression of PD-L1 in human osteosarcoma U2OS cells. We found that the upregulation of PD-L1 expression after high LET carbon-ion irradiation was greater than that induced by X-rays at the same physical and relative biological effectiveness (RBE) dose, and that the upregulation of PD-L1 induced by high LET carbon-ion irradiation was predominantly dependent on ataxia telangiectasia and Rad3-related (ATR) kinase activity. Moreover, we showed that the downstream signaling, e.g. STAT1 phosphorylation and IRF1 expression, was upregulated to a greater extent after high LET carbon-ion irradiation than X-rays, and that IRF1 upregulation was also ATR dependent. Finally, to visualize PD-L1 molecules on the cell surface in 3D, we applied immunofluorescence-based super-resolution imaging. The three-dimensional structured illumination microscopy (3D-SIM) analyses revealed substantial increases in the number of presented PD-L1 molecules on the cell surface after high LET carbon-ion irradiation compared with X-ray irradiation. © 2021 The Author(s) 2021. Published by Oxford University Press on behalf of The Japanese Radiation Research Society and Japanese Society for Radiation Oncology. |
anti-PD-1/PD-L1 therapy; DNA damage response; high linear energy transfer (LET) carbon-ion therapy; PD-L1 expression |
Carbon; Cell membranes; Cytology; Diseases; Ionizing radiation; Ions; Molecules; Oncology; Radiotherapy; Anti-PD-1/programmed death ligand 1 therapy; Carbon ion therapy; Carbon ions; DNA damage response; High linear energy transfer carbon-ion therapy; High linear energy transfers; Human osteosarcoma; Ions irradiation; Programmed death ligand 1 expression; Up-regulation; Energy transfer; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one; 3-amino-6-(4-(methylsulfonyl)phenyl)-N-phenylpyrazine-2-carboxamide; ATM protein; ATM protein, human; ATR protein, human; CD274 protein, human; interferon regulatory factor 1; IRF1 protein, human; messenger RNA; morpholine derivative; programmed death 1 ligand 1; pyrazine derivative; pyrone derivative; RNA; STAT1 protein; STAT1 protein, human; sulfone; tumor p |
Oxford University Press |
04493060 |
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34196706 |
Article |
Q2 |
643 |
7838 |
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198 |
Kartika R.W., Alwi I., Yunir E., Waspadji S., Suyatna F.D., Bardosono S., Immanuel S., Sungkar S., Rachmat J., Silalahi T., Reksodiputro M.H. |
57223447932;15055173800;36520254800;8678136400;56039633100;21933841000;57272979000;57016857300;6507225348;56275255400;35090488800; |
Efficacy of Combining Hyaluronic Acid and Platelet-Rich Fibrin in Diabetic Foot Ulcer |
2021 |
Jordan Journal of Biological Sciences |
14 |
3 |
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607 |
611 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115791952&partnerID=40&md5=76c1dc1bbdde331f901d412f6b6a83ba |
Doctoral Program in Medical Science Faculty of Medicine Universitas Indonesia, Department of Thoracic, Cardiac and Vascular Surgery, Faculty of Medicine Krida Wacana Christian University, Indonesia; Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Clinical Pharmacology, Faculty of Medicine Universitas Indonesia, Indonesia; Department of Clinical Nutrition, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Clinical Pathology, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Parasitology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Thoracic Cardiac and Vascular Surgery, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Internal Medicine, Faculty of Medicine Krida Wacana Christian University, Jakarta, Indonesia; Department of Otorhinolaryngology, Facial Plastic Reconstructive Division, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Kartika, R.W., Doctoral Program in Medical Science Faculty of Medicine Universitas Indonesia, Department of Thoracic, Cardiac and Vascular Surgery, Faculty of Medicine Krida Wacana Christian University, Indonesia; Alwi, I., Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Yunir, E., Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Waspadji, S., Department of Internal Medicine, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Suyatna, F.D., Department of Clinical Pharmacology, Faculty of Medicine Universitas Indonesia, Indonesia; Bardosono, S., Department of Clinical Nutrition, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Immanuel, S., Department of Clinical Pathology, Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Sungkar, S., Department of Parasitology, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Rachmat, J., Department of Thoracic Cardiac and Vascular Surgery, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Silalahi, T., Department of Internal Medicine, Faculty of Medicine Krida Wacana Christian University, Jakarta, Indonesia; Reksodiputro, M.H., Department of Otorhinolaryngology, Facial Plastic Reconstructive Division, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Objectives: A chronic complication of type-2 diabetes mellitus (DMT-2) is Diabetic Foot Ulcer (DFU). The main treatment used in DFU is wound cleansing, followed by dressing the wound as a local control to increase tissue granulation and epithelialization. This study aims to compare the efficacy of the combination of Hyaluronic Acid with Platelet Rich Fibrin (HAPRF) and Platelet Rich Fibrin alone in DFU. Methods: We conducted a randomized controlled trial from July 2019 to April 2020. The study was approved by the Ethics Committee of the Faculty of Medicine of Universitas Indonesia ID 0855 / UN2.F1 / ETIK / 2018. Informed consent was obtained from the patients. This was a randomized clinical study to compare the efficacy of HAPRF and PRF in DFU one week post debridement. Twenty DFU samples were collected divided into 2 treatment groups: topical treatment using HAPRF compare with PRF alone. Assessment for wounds improvement was recorded using a digital camera 48 mega pixel with an accuracy of 0.1% on day-0, 3, 7, and 14. The results of the wound photographs were processed using ImageJ software. The granulation area (GA) and wound area (WA) were evaluated by IBM SPSS software v.20. The general data description was presented in median (range) value and parameter’s differences were conducted using Mann–Whitney test Results: The two treatment groups showed insignificant difference in characteristics between both group before intervention. The mean granulation width after two weeks of use HAPRF was 97.4% and PRF was 81.9%. Statistical analysis using Mann Whitney test showed granulation area of HAPRF group was significantly different compared with PRF group on day-3(p=0.047), day-7 ( p = 0.004) and day-14 ( p < 0.001). At the end of the wound healing process, the HAPRF group was significantly different compared with PRF group on Δ day 0−3 ( p=0.048), Δ day 0−7 ( p = 0.039), and Δ day 0−14 ( p = 0.023). Conclusions: HAPRF improves wound healing rate through increasing granulation tissue and epithelialization compared with PRF only in diabetic foot ulcer after 2 weeks post debridement compared to PRF. © 2021, Jordan Journal of Biological Sciences. All Rights Reserved. |
Delta Wound Area; Diabetic ulcer; Granulation Area; Hyaluronic Acid; Platelet Rich Fibrin |
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Hashemite University |
19956673 |
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Article |
Q3 |
216 |
18398 |
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199 |
Tunjungputri R.N., Tetrasiwi E.N., Veronica M., Pandelaki J., Ibrahim F., Nelwan E.J. |
56342194400;57267704700;57268337000;35759266900;57226400046;14527452900; |
Vaccine-associated disease enhancement: a case report of post-vaccination COVID-19 |
2021 |
International Journal of Antimicrobial Agents |
58 |
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21003575 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115401929&doi=10.1016%2fj.ijantimicag.2021.106421.86&partnerID=40&md5=46457ba71f5610aae7b204755fcef50d |
Department of Internal Medicine, Faculty of Medicine Universitas Indonesia and Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Department of Radiology, Faculty of Medicine Universitas Indonesia and Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Microbiology Department, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Division of Tropical and Infectious Diseases, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia and Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Infectious Disease and Immunology Research Center—IMERI, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Tunjungputri, R.N., Department of Internal Medicine, Faculty of Medicine Universitas Indonesia and Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Tetrasiwi, E.N., Department of Internal Medicine, Faculty of Medicine Universitas Indonesia and Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Veronica, M., Department of Internal Medicine, Faculty of Medicine Universitas Indonesia and Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Pandelaki, J., Department of Radiology, Faculty of Medicine Universitas Indonesia and Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Ibrahim, F., Microbiology Department, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Nelwan, E.J., Department of Internal Medicine, Faculty of Medicine Universitas Indonesia and Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia, Division of Tropical and Infectious Diseases, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia and Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia, Infectious Disease and Immunology Research Center—IMERI, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
[No abstract available] |
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Elsevier B.V. |
09248579 |
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Article |
Q1 |
1454 |
2387 |
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200 |
Fadrian F., Nelwan E.J., Kurniawan J., Pohan H.T. |
57268114000;14527452900;57193251655;23474782900; |
Risk of infection with multiple pathogen in post liver transplantation patient in referral centre in Jakarta, Indonesia |
2021 |
International Journal of Antimicrobial Agents |
58 |
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21003320 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115366248&doi=10.1016%2fj.ijantimicag.2021.106421.61&partnerID=40&md5=e23afb1d78408e73580d689f6327bb02 |
Department of Internal Medicine;; Division of Tropical and Infectious Disease;; Division of Hepatology Faculty of Medicine Universitas Indonesia, Ciptomangunkusumo Hospital, Jakarta, Indonesia |
Fadrian, F., Department of Internal Medicine;; Nelwan, E.J., Department of Internal Medicine;, Division of Tropical and Infectious Disease;; Kurniawan, J., Department of Internal Medicine;, Division of Hepatology Faculty of Medicine Universitas Indonesia, Ciptomangunkusumo Hospital, Jakarta, Indonesia; Pohan, H.T., Department of Internal Medicine;, Division of Tropical and Infectious Disease; |
[No abstract available] |
aspergillosis.; biloma; CMV; post liver transplantation infection |
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Elsevier B.V. |
09248579 |
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Article |
Q1 |
1454 |
2387 |
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201 |
Tunjungputri R.N., Tetrasiwi E.N., Rizqa T., Mulansari N.A., Harimurti K. |
56342194400;57267704700;57268337300;36519326000;23473513200; |
Parenteral and oral anticoagulant treatment for hospitalized and post-discharge patients with COVID-19: A systematic review |
2021 |
International Journal of Antimicrobial Agents |
58 |
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21003587 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115349747&doi=10.1016%2fj.ijantimicag.2021.106421.87&partnerID=40&md5=c258c13fa4bd248528cd36e04d4d4fd4 |
Department of Internal Medicine, Universitas Indonesia, Faculty of Medicine and Cipto Mangunkusumo National Centre General Hospital;; Division of Hematology and Medical Oncology, Department of Internal Medicine, Universitas Indonesia, Faculty of Medicine and Cipto Mangunkusumo National Centre General Hospital |
Tunjungputri, R.N., Department of Internal Medicine, Universitas Indonesia, Faculty of Medicine and Cipto Mangunkusumo National Centre General Hospital;; Tetrasiwi, E.N., Department of Internal Medicine, Universitas Indonesia, Faculty of Medicine and Cipto Mangunkusumo National Centre General Hospital;; Rizqa, T., Department of Internal Medicine, Universitas Indonesia, Faculty of Medicine and Cipto Mangunkusumo National Centre General Hospital;; Mulansari, N.A., Division of Hematology and Medical Oncology, Department of Internal Medicine, Universitas Indonesia, Faculty of Medicine and Cipto Mangunkusumo National Centre General Hospital; Harimurti, K., Department of Internal Medicine, Universitas Indonesia, Faculty of Medicine and Cipto Mangunkusumo National Centre General Hospital; |
[No abstract available] |
anticoagulant; COVID-19; thromboprophylaxis.; VTE |
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Elsevier B.V. |
09248579 |
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Article |
Q1 |
1454 |
2387 |
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202 |
Rusdi N.K., Purwaningsih E.H., Hestiantoro A., Elya B., Kusmardi K. |
57211475250;57186723500;8743255100;14014224500;56966625300; |
In vivo antimammary tumor effects of soybean extract with targeted lunasin (ET-Lun) |
2021 |
Pharmacognosy Journal |
13 |
5 |
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1269 |
1276 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115297490&doi=10.5530%2fpj.2021.13.160&partnerID=40&md5=d96a1538654afeda0377ba6b0d8a5e38 |
Doctoral Program for Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Faculty of Pharmacy and Sciences, Universitas Muhammadiyah Prof. DR. Hamka, Jakarta, Indonesia; Department of Pharmacy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department Obstetrics and Gynaecology, School of Medicine, Universitas Indonesia, Dr Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Phytochemistry, Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia; Department of Anatomic Pathology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Drug Development Research Cluster, Indonesian Medical Education and Reseach Institute, Universitas INDONESIA, Indonesia; Human Cancer Research Cluster, Indonesian Medical Education and Research Institute, Universitas INDONESIA, Indonesia |
Rusdi, N.K., Doctoral Program for Biomedical Sciences, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Faculty of Pharmacy and Sciences, Universitas Muhammadiyah Prof. DR. Hamka, Jakarta, Indonesia; Purwaningsih, E.H., Department of Pharmacy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Drug Development Research Cluster, Indonesian Medical Education and Reseach Institute, Universitas INDONESIA, Indonesia; Hestiantoro, A., Department Obstetrics and Gynaecology, School of Medicine, Universitas Indonesia, Dr Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Elya, B., Department of Phytochemistry, Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia; Kusmardi, K., Department of Anatomic Pathology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Drug Development Research Cluster, Indonesian Medical Education and Reseach Institute, Universitas INDONESIA, Indonesia, Human Cancer Research Cluster, Indonesian Medical Education and Research Institute, Universitas INDONESIA, Indonesia |
Background/Objective: Lunasin is a peptide, consist of 44 amino acids which have anti-cancer, antioxidant, and anti-inflammatory activity. The price of commercial Lunasin was very expensive due to the high cost of lunasin synthesis and the lack of methods to obtain the pure lunasin weight from plant sources, involving time-consuming analytical instruments. To overcome these problems, the soybean extract with targeted Lunasin (ET-Lun) was made. The aim of this study was to investigate anti-cancer properties of ET-Lun in breast cancer models in vivo. Methods: Effect of ET-Lun was evaluated in 7,12-Dimetilbenz[a]antrasen (DMBA) induced breast cancer rat model. Tumor Mass, volume, and number were measured. The expression of HER2 and EGFR from each treatment group in DMBA-induced rat was evaluated using immunohistochemistry. Results: The results shown that ET-Lun could reduced tumor volume (p=0,021). ET-Lun decreased EGFR expression compared to negative control DMBA (p=0,012). Conclusions: These results indicated that the ET-Lun has anti-breast cancer activity in vivo. © 2021 Phcogj.Com. |
Breast cancer; EGFR; HER2; In-vivo; Soybean |
dimethylbenz[a]anthracene; epidermal growth factor receptor; epidermal growth factor receptor 2; lunasin; peptide; soybean extract; tamoxifen; unclassified drug; aged; animal experiment; animal model; animal tissue; antineoplastic activity; Article; breast cancer; controlled study; female; immunohistochemistry; in vivo study; nonhuman; protein expression; rat; soybean; tumor number; tumor volume |
EManuscript Technologies |
09753575 |
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Article |
Q3 |
268 |
15961 |
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206 |
Findyartini A., Greviana N., Hanum C., Husin J.M., Sudarsono N.C., Krisnamurti D.G.B., Rahadiani P. |
56543777300;57197709749;57257072300;57221607411;57201862518;55934951600;55524183700; |
Supporting newly graduated medical doctors in managing COVID-19: An evaluation of a Massive Open Online Course in a limitedresource setting |
2021 |
PLoS ONE |
16 |
9 September |
e0257039 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114841740&doi=10.1371%2fjournal.pone.0257039&partnerID=40&md5=d823d8aaf9a69d130347230f477800d5 |
Medical Education Center, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Medical Education, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Sports and Exercise Study, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Community Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Center for E-learning, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Pharmacy, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Findyartini, A., Medical Education Center, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Department of Medical Education, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Greviana, N., Medical Education Center, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Department of Medical Education, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Hanum, C., Medical Education Center, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Husin, J.M., Medical Education Center, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Sudarsono, N.C., Sports and Exercise Study, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Department of Community Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Krisnamurti, D.G.B., Center for E-learning, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Department of Pharmacy, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Rahadiani, P., Center for E-learning, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Introduction Newly graduated medical doctors in their internships are positioned to strengthen the front line in combating COVID-19. We developed a Massive Open Online Course (MOOC) to equip them with adequate knowledge for COVID-19 management. This paper aims to analyze the MOOC and evaluate participant satisfaction and increase in knowledge after completing the course. Methods An observational study was conducted. Quantitative data were obtained from questionnaires and pre-and post-Tests. Responses to open-ended questions of the questionnaires were collected. Analysis using the Quality Reference Framework was also completed. Results The MOOC consisted of fundamental knowledge of COVID-19 (Part A) and further enrichment (Part B), and the content was written in the Indonesian language. A total of 3,424 and 2,462 participants completed the course in August and November 2020, respectively. Most participants agreed that the platform was easy to navigate, the design was interesting, and the content was aligned with their needs. Pre-and post-Test scores in Part A s subjects increased significantly. Factors contributing to and inhibiting usability and areas for improvement were further highlighted. Discussion The use of a specific quality framework facilitated a comprehensive evaluation of the MOOC s strengths, weaknesses, and areas for future improvements. The participants satisfaction and pre-and post-Test results showed that the current MOOC holds great potential benefit for continuing education for medical interns joining the frontliners during the pandemic. Future implementation should consider increasing the quality of learning resources, scaling up the platform and its technical supports, and enhancing organizational supports. © 2021 Public Library of Science. All rights reserved. |
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education; epidemiology; human; Indonesia; medical education; procedures; program evaluation; questionnaire; COVID-19; Education, Distance; Education, Medical, Graduate; Educational Measurement; Humans; Indonesia; Program Evaluation; Surveys and Questionnaires |
Public Library of Science |
19326203 |
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34506524 |
Article |
Q1 |
990 |
4434 |
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