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858 |
Eldafira E., Prasasty V.D., Abinawanto A., Syahfirdi L., Pujianto D.A. |
57204963791;56019989700;55625129700;57222327356;8745734300; |
Polymorphisms of estrogen receptor-α and estrogen receptor-β genes and its expression in endometriosis [Östrojen reseptör-α ve östrojen reseptör-β genlerinin polimorfizmi ve endometriozisde ifadelenmeleri] |
2021 |
Turkish Journal of Pharmaceutical Sciences |
18 |
1 |
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91 |
95 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102272548&doi=10.4274%2ftjps.galenos.2019.94914&partnerID=40&md5=ca75ed564cc74a659022ab862e0096b8 |
Universitas Indonesia, Faculty of Medicine, Department of Medical Biology, Depok, Indonesia; Universitas Indonesia, Faculty of Mathematics and Natural Sciences, Department of Biology, Jakarta, Indonesia; Atma Jaya Catholic University of Indonesia, Faculty of Biotechnology, Jakarta, Indonesia |
Eldafira, E., Universitas Indonesia, Faculty of Medicine, Department of Medical Biology, Depok, Indonesia, Universitas Indonesia, Faculty of Mathematics and Natural Sciences, Department of Biology, Jakarta, Indonesia; Prasasty, V.D., Atma Jaya Catholic University of Indonesia, Faculty of Biotechnology, Jakarta, Indonesia; Abinawanto, A., Universitas Indonesia, Faculty of Mathematics and Natural Sciences, Department of Biology, Jakarta, Indonesia; Syahfirdi, L., Universitas Indonesia, Faculty of Mathematics and Natural Sciences, Department of Biology, Jakarta, Indonesia; Pujianto, D.A., Universitas Indonesia, Faculty of Medicine, Department of Medical Biology, Depok, Indonesia |
Objectives: Endometriosis is a common gynecological disorder, characterized by the presence of endometrial-like tissue in the extrauterine location. The increasing estradiol concentration can influence endometriosis risk and estrogen receptor (ER) activity. Polymorphism in ER causes gene expression alteration and influences hormone-receptor interaction. This research aims to determine ER genetic polymorphisms in endometriosis pathogenesis. Materials and Methods: This study was performed on case-control polymorphisms, which compared 83 women with endometriosis and 76 women without endometriosis. However, the samples used for ER gene expression analysis and estrogen level measurement were obtained from 18 women with endometriosis and 18 women without endometriosis. Polymerase chain reaction-restriction fragment length polymorphism was used to determine ER genetic polymorphisms. Chi-square, Mann-Whitney test, Spearman’s correlation (p), t-independent, and two-tailed tests were used to analyze the data. Results: Association between the allele ERα rs9340799 A/G and endometriosis was significantly different (p=0.012), whereas rs2234693 T/C polymorphism showed no association with endometriosis. The correlation between the genotype frequencies of allele ERβ rs4986938 G/A and endometriosis was found significantly different (p=0.015; p=0.034). Conclusion: Estradiol level and ERβ expression increases, polymorphism genotypes and alleles of ERβ rs4986938 G/A gene and allele frequency of ERα rs9340799 A/G gene have roles in endometriosis. © Turk J Pharm Sci, Published by Galenos Publishing House. |
Endometriosis; Estradiol (E2); Estrogen receptor (ERα and ERβ) |
ammonium acetate; dodecyl sulfate sodium; estradiol; estrogen; estrogen receptor alpha; estrogen receptor beta; genomic DNA; adult; agar gel electrophoresis; allele; Article; case control study; centrifugation; controlled study; DNA extraction; DNA polymorphism; endometriosis; female; gene; gene amplification; gene frequency; genotype; human; illumination; intron; major clinical study; polymerase chain reaction; receptor gene; restriction fragment length polymorphism; rs2234693 gene; rs4986938 gene; spectrophotometry |
Turkish Pharmacists Association |
1304530X |
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Article |
Q3 |
241 |
17155 |
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859 |
Gunardi W.D., Karuniawati A., Umbas R., Bardosono S., Lydia A., Soebandrio A., Safari D. |
57222314683;54886816200;6602634832;21933841000;8451287200;8602893200;23493586700; |
Biofilm-Producing Bacteria and Risk Factors (Gender and Duration of Catheterization) Characterized as Catheter-Associated Biofilm Formation |
2021 |
International Journal of Microbiology |
2021 |
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8869275 |
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5 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102259916&doi=10.1155%2f2021%2f8869275&partnerID=40&md5=2173f2f0a162e1277f45979d11bf433c |
Department of Clinical Microbiology, Faculty of Medicine, Krida Wacana Christian University, Jakarta, 1151, Indonesia; Department of Clinical Microbiology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10320, Indonesia; Department of Urology, FMUI-CMH, Jakarta, 10430, Indonesia; Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Eijkman Institute for Molecular Biology, Jakarta, 10430, Indonesia |
Gunardi, W.D., Department of Clinical Microbiology, Faculty of Medicine, Krida Wacana Christian University, Jakarta, 1151, Indonesia; Karuniawati, A., Department of Clinical Microbiology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10320, Indonesia; Umbas, R., Department of Urology, FMUI-CMH, Jakarta, 10430, Indonesia; Bardosono, S., Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Lydia, A., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Soebandrio, A., Eijkman Institute for Molecular Biology, Jakarta, 10430, Indonesia; Safari, D., Eijkman Institute for Molecular Biology, Jakarta, 10430, Indonesia |
Background. A catheter-associated urinary tract infection (CA-UTI) is preceded by biofilm formation, which is related to several risk factors such as gender, age, diabetic status, duration of catheterization, bacteriuria before catheterization, virulence gene factor, and antibiotic usage. Aims. This study aims to identify the microbial composition of catheter samples, including its corresponding comparison with urine samples, to determine the most important risk factors of biofilm formation and characterize the virulence gene factors that correlate with biofilm formation. Methods. A longitudinal cross-sectional study was conducted on 109 catheterized patients from September 2017 to January 2018. The risk factors were obtained from the patients' medical records. All catheter and urine samples were cultured after removal, followed by biomass quantification. Isolate identification and antimicrobial susceptibility testing were performed using the Vitex2 system. Biofilm-producing bacteria were identified by the Congo Red Agar (CRA) method. A PCR test characterized the virulence genes of dominant bacteria (E. coli). All data were collected and processed for statistical analysis. Results. Out of 109 catheterized patients, 78% of the catheters were culture positive, which was higher than those of the urine samples (37.62%). The most common species isolated from the catheter cultures were Escherichia coli (28.1%), Candida sp. (17.8%), Klebsiella pneumoniae (15.9%), and Enterococcus faecalis (13.1%). E. coli (83.3%) and E. faecalis (78.6%) were the main isolates with a positive CRA. A statistical analysis showed that gender and duration prior to catheterization were associated with an increased risk of biofilm formation p<0.05. Conclusion. E. coli and E. faecalis were the most common biofilm-producing bacteria isolated from the urinary catheter. Gender and duration are two risk factors associated with biofilm formation, therefore determining the risk of CAUTI. The presence of PapC as a virulence gene encoding pili correlates with the biofilm formation. Biofilm-producing bacteria, female gender, duration of catheterization (more than five days), and PapC gene presence have strong correlation with the biofilm formation. To prevent CAUTI, patients with risk factors should be monitored by urinalysis tests to detect earlier the risk of biofilm formation. © 2021 Wani Devita Gunardi et al. |
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Hindawi Limited |
1687918X |
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Article |
Q3 |
696 |
7161 |
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861 |
Umas R.A., Supriadi S., Whulanza Y., Hasan A.A.A.F., Kreshanti P. |
57222252781;16040272500;36807053500;57222257599;36192866200; |
Evaluating the Gear Stress of Novel Reverse Rotation Bit Manual Screwdriver Design for Miniscrew Implants |
2021 |
Journal of Mechanical Engineering |
18 |
1 |
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175 |
192 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102086175&partnerID=40&md5=0196752c2bad6ab9b05bb97c07712c5b |
Department of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, 16424, Indonesia; Cleft and Craniofacial Center Cipto Mangunkusumo Hospital, Plastic and Reconstructive Surgery Division, Department of Surgery, Faculty of Medicine, Universitas Indonesia, Indonesia |
Umas, R.A., Department of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, 16424, Indonesia; Supriadi, S., Department of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, 16424, Indonesia; Whulanza, Y., Department of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, 16424, Indonesia; Hasan, A.A.A.F., Department of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Kampus UI Depok, 16424, Indonesia; Kreshanti, P., Cleft and Craniofacial Center Cipto Mangunkusumo Hospital, Plastic and Reconstructive Surgery Division, Department of Surgery, Faculty of Medicine, Universitas Indonesia, Indonesia |
One of the problems faced by the screwdrivers used for craniomaxillofacial implant fixation is that the maximum torque required for implant removal is significantly higher than the maximum torque needed for inserting implants. Another problem is that the hand torque produced by a right-handed person is lower in the counterclockwise direction, which is the removal direction for miniscrews. The novel design presented here of a manual screwdriver equipped with an epicyclic gear will produce a reverse bit rotation and provide the mechanical advantage of higher torque output. In this study, simulations were conducted by varying the torque input within the range of 0-1000 Nmm with an applied load in each simulation to be adapted based on the epicyclic gear set. The materials used in this study are AISI 316L and Ti6Al4V. The maximum Von Mises stress value was observed in the sun gear from the second gear set at 522.59 MPa (AISI 316L) and 430.76 MPa (Ti6Al4V) for the maximum torque input, which was followed by the planetary and ring gear from the second gear set and then the planetary gear, ring gear, and sun gear from the first gear set. The total deformation also showed the difference between the two materials; the deformation when using AISI 316L as the material was lower than when using Ti6Al4V. © 2021 Faculty of Mechanical Engineering. All Rights Reserved. |
Epicyclic Gear; Maxillofacial Implant; Surgical Screwdriver |
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UiTM Press |
18235514 |
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Article |
Q3 |
216 |
18402 |
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866 |
Lesmana C.R.A., Herjuningtyas C., Inggriani S., Pratiwi Y.E., Lesmana L.A. |
8977683000;57222165389;35329838800;57222163306;55920139300; |
Bedside Percutaneous Approach in a Critically Ill ICU Patient with Complex Pancreatobiliary Disorder Followed by Endoscopic Approach: Lessons Learnt from a Tertiary Referral Center |
2021 |
Case Reports in Gastroenterology |
15 |
1 |
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210 |
217 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101734257&doi=10.1159%2f000513282&partnerID=40&md5=b06514b9ba8afa5ed7ce24173ab5b336 |
Hepatobiliary Division, Department of Internal Medicine, Dr. Cipto Mangunkusumo National General Hospital, Medical Faculty University of Indonesia, Jakarta, Indonesia; Digestive Disease and GI Oncology Center, Medistra Hospital, Jakarta, Indonesia; Department of Anesthesiology, Medistra Hospital, Jakarta, Indonesia; Department of Radiology, Medistra Hospital, Jakarta, Indonesia |
Lesmana, C.R.A., Hepatobiliary Division, Department of Internal Medicine, Dr. Cipto Mangunkusumo National General Hospital, Medical Faculty University of Indonesia, Jakarta, Indonesia, Digestive Disease and GI Oncology Center, Medistra Hospital, Jakarta, Indonesia; Herjuningtyas, C., Department of Anesthesiology, Medistra Hospital, Jakarta, Indonesia; Inggriani, S., Department of Radiology, Medistra Hospital, Jakarta, Indonesia; Pratiwi, Y.E., Digestive Disease and GI Oncology Center, Medistra Hospital, Jakarta, Indonesia; Lesmana, L.A., Digestive Disease and GI Oncology Center, Medistra Hospital, Jakarta, Indonesia |
Pancreatobiliary disorder is a challenging clinical condition, especially when this condition is causing severe infection or biliary sepsis, and sometimes it requires intensive care unit (ICU) treatment. Biliary drainage is the mainstay of therapy; however, the choice of the drainage method is dependent on the patient's clinical condition and the disease itself. A 79-year-old female was transferred on a ventilator to our ICU from another hospital due to biliary sepsis, a large common bile duct stone, and an infected pancreatic pseudocyst. The patient also has other comorbidities such as heart problems, hypothyroidism, and diabetes mellitus. Bedside percutaneous transhepatic biliary drainage without fluoroscopy and percutaneous cyst aspiration was successfully performed, which improved the patient's condition; this was followed by an endoscopic approach, i.e., endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic ultrasound-guided pancreatic pseudocyst drainage. The clinical improvement showed itself in the change of the patient's respiratory status and ventilator mode. In conclusion, the percutaneous approach has a big role in managing critically ill patients in the ICU setting. However, expertise, training experience, and a multidisciplinary team approach are very important for successful management and patient outcome. © 2021 The Author(s). Published by S. Karger AG, Basel. |
Biliary sepsis; Common bile duct stone; Pancreatic pseudocyst; Percutaneous approach |
amikacin; antibiotic agent; bilirubin; C reactive protein; carcinoembryonic antigen; insulin; levothyroxine; piperacillin plus tazobactam; triacylglycerol lipase; aged; Article; artificial ventilation; biliary tract drainage; biliary tract endoscopy; case report; clinical article; common bile duct stone; comorbidity; continuous positive airway pressure; critically ill patient; cyst aspiration; diabetes mellitus; echography; endoscopic retrograde cholangiopancreatography; female; fluoroscopy; human; hypothyroidism; intensive care unit; jaundice; magnetic resonance cholangiopancreatography; pancreas disease; pancreas pseudocyst; sepsis |
S. Karger AG |
16620631 |
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Article |
Q3 |
247 |
16829 |
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867 |
Ibrahim F., Sahlan M., Ginting M.J., Kartika Pratami D., Hermansyah H., Wijanarko A. |
54886001500;57189182661;57212472114;57222140683;15759436800;6506885367; |
Isolation of protein from the spine venom of pterois volitans found in the indonesian ocean, using a heating process, for anticancer, antiretroviral, antibacterial, and antioxidant assays |
2021 |
International Journal of Applied Pharmaceutics |
13 |
special issue 2 |
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53 |
58 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101657433&doi=10.22159%2fijap.2021.v13s2.10&partnerID=40&md5=7efd709314f7d32aab3f98fec52eeb8d |
Virology and Cancer Pathobiology Research Centre, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, 10320, Indonesia; Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, West Java, 16424, Indonesia; Research Centre for Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, West Java, 16424, Indonesia; Faculty of Mathematics and Natural Science, Universitas Indonesia, Depok, West Java, 16424, Indonesia; Laboratory of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Pancasila University, South Jakarta, DKI Jakarta, 12640, Indonesia |
Ibrahim, F., Virology and Cancer Pathobiology Research Centre, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, 10320, Indonesia; Sahlan, M., Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, West Java, 16424, Indonesia, Research Centre for Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, West Java, 16424, Indonesia; Ginting, M.J., Faculty of Mathematics and Natural Science, Universitas Indonesia, Depok, West Java, 16424, Indonesia; Kartika Pratami, D., Laboratory of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Pancasila University, South Jakarta, DKI Jakarta, 12640, Indonesia; Hermansyah, H., Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, West Java, 16424, Indonesia; Wijanarko, A., Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, West Java, 16424, Indonesia |
Objective: This research investigates the antibacterial, anticancer, antioxidant, and antiretroviral activities of the lionfish spine poison extract. Methods: Isolation and purification of the phospholipase A2 (PLA2) protein obtained from the spine poison were conducted through the following stages, including, extraction of the venom by sonication, heating, and purification using gradual saturation levels of ammonium sulfate. Furthermore, the purity and concentration of PLA2 were analyzed using the Lowry test and Marinetti’s method, respectively, while its protein content was ascertained through SDS-PAGE. Toxicity was then evaluated employing the brine shrimp lethality test (BSLT), and its anticancer activity was assessed in human cervical carcinoma cells (HeLa cells). Finally, its antioxidant, antibacterial, and antiretroviral activities were analyzed using the DPPH method, agar diffusion test against Salmonella sp. and E. coli, and SRV-2 and RT-qPCR tests, respectively. Results: The protein demonstrated 37.79% inhibition for anticancer activity, IC50 1312 ppm for antioxidant activity, 98.81%, and 89.28% inhibition of E. coli and Salmonella sp. respectively for antibacterial activity and 98.13% inhibition for antiretroviral activity. Conclusion: It can be concluded that lionfish (Pterois volitans) has the potential to be developed as an antioxidant, anticancer, antibacterial, and antiretroviral agent. Furthermore, the pharmacological activity of its spine venom was determined by isolating PLA2 protein from its extract, using an optimum heating temperature of 70 °C and an ammonium sulfate saturation level of 80%. © 2021 The Authors. Published by Innovare Academic Sciences Pvt Ltd. T. |
Antibacterial; Anticancer; Antioxidant; Antiretroviral; Crude venom; Pterois volitans |
ammonium sulfate; antineoplastic agent; antioxidant; antiretrovirus agent; caspase 3; chloramphenicol; phospholipase A2; venom; agar diffusion; antibacterial activity; antineoplastic activity; antioxidant activity; antiviral activity; Article; bacterial growth; controlled study; cytotoxicity; DNA extraction; DPPH radical scavenging assay; enzyme activity; enzyme inhibition; enzyme linked immunosorbent assay; Escherichia coli; heating; HeLa cell line; human; human cell; hydroxyl radical scavenging assay; IC50; minimum inhibitory concentration; MTT assay; nonhuman; oxygen saturation; polyacrylamide gel electrophoresis; protein content; protein isolation; protein purification; Pterois volitans; Salmonella; shrimp; Staphylococcus aureus; temperature; ultrasound; ultraviolet visible spectroscop |
Innovare Academics Sciences Pvt. Ltd |
09757058 |
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Article |
Q3 |
238 |
17272 |
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870 |
Prasetyo M., Rahardja R.R., Yanuar A., Prihartono J., Setiawan S.I. |
57192905252;57222100194;57222087272;6602605635;57195939543; |
Ultrasonography evaluation of the normal ulnar nerve in adult: Comparison of the cross-sectional area at elbow extension and flexion |
2021 |
European Journal of Radiology Open |
8 |
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100331 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101370509&doi=10.1016%2fj.ejro.2021.100331&partnerID=40&md5=f9e415e711bd67bbe8b7b71cf1b20376 |
Department of Radiology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Department of Neurology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Prasetyo, M., Department of Radiology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Rahardja, R.R., Department of Radiology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Yanuar, A., Department of Neurology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Prihartono, J., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Setiawan, S.I., Department of Radiology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia |
Background: Cross-sectional area (CSA) measurement of the ulnar nerve in the adult population by using ultrasonography (US) at elbow extension and flexion has previously been reported, but not much evidence showed a significant difference between elbow extension and flexion position. Purpose: To compare the ulnar nerve CSA between elbow extension and flexion position. Methods: A comparative cross-sectional study was conducted by involving 36 healthy adults with normally functioning ulnar nerve proven by Nerve Conduction Study (NCS) or Electroneurography. The ulnar nerve CSA was measured on each elbow by using US at the level of the medial epicondyle, 2 cm distal and 2 cm proximal from the medial epicondyle. Results: The average ulnar nerve CSA at the medial epicondyle, 2 cm distal and proximal to the medial epicondyle at elbow extension respectively were 5.95 ± 0.74 mm2, 6.27 ± 0.92 mm2, and 5.92 ± 0.73 mm2. At elbow flexion, the average ulnar nerve CSA at the positions was 5.70 ± 0.83 mm2, 5.23 ± 0.87 mm2, dan 5.73 ± 0.71 mm2 respectively. The CSA of the ulnar nerve at elbow extension was significantly larger compared to the flexion position in the three areas observed in this study (p < 0.001). Conclusion: The CSA of the ulnar nerve at elbow extension position was larger compared to the flexion position. Elbow position should be considered in measuring CSA of the ulnar nerve. © 2021 The Author(s) |
Cross-sectional area; Medial epicondyle; Ulnar nerve; Ultrasonography |
adult; article; clinical article; controlled study; cross-sectional study; echography; elbow flexion; electroneurography; female; human; human experiment; male; nerve conduction; ulnar nerve |
Elsevier Ltd |
23520477 |
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Article |
Q3 |
490 |
10260 |
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871 |
Turana Y., Widyantoro B., Situmorang T.D., Delliana J., Roesli R.M.A., Danny S.S., Suhardjono, Sofiatin Y., Hermiawaty E., Kuncoro A.S., Barack R., Beaney T., Ster A.C., Poulter N.R., Santoso A. |
56083326000;35286148600;57202120316;57208720930;26428909500;56221848700;57205723084;56815068100;57208721982;56008103000;57202111674;55614780900;57221978746;7006154423;36905206100; |
May measurement Month 2018: An analysis of blood pressure screening results from Indonesia |
2021 |
European Heart Journal, Supplement |
22 |
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H66 |
H69 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101322980&doi=10.1093%2fEURHEARTJ%2fSUAA031&partnerID=40&md5=16a05b90991c40fdd180dd4e051eaaad |
Department of Neurology, School of Medicine and Health Science, Atma Jaya Catholic University of Indonesia, Jakarta, 14440, Indonesia; Department of Cardiology - Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia; Division of Nephrology, Department of Internal Medicine, PGI Cikini Hospital, Jakarta, 10330, Indonesia; Department of Cardiology, Directorate of Non-Communicable Disease, Ministry of Health - Republic of Indonesia, Jalan Percetakan Negara 29, Jakarta, 10560, Indonesia; Department of Internal Medicine, Faculty of Medicine, Padjadjaran University, Hasan Sadikin General Hospital, Bandung, 40161, Indonesia; Division of Nephrology and Hypertension, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto, Mangunkusumo National General Hospital, Jalan Pangeran Diponegoro No: 71, Jakarta, 10430, Indonesia; Department of Public Health, Faculty of Medicine, Padjadjaran University, Jalan Prof. Eijkman 38, Bandung, 40161, Indonesia; Department of Neurology, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia; Department of Cardiology, MMC Hospital, Jakarta, Indonesia; Imperial Clinical Trials Unit, Imperial College London, Stadium House, 68 Wood Lane, Shepherd's Bush, London, W12 7RH, United Kingdom; Department of Primary Care and Public Health, Imperial College London, St Dunstan's Road, London, W6 8RP, United Kingdom |
Turana, Y., Department of Neurology, School of Medicine and Health Science, Atma Jaya Catholic University of Indonesia, Jakarta, 14440, Indonesia; Widyantoro, B., Department of Cardiology - Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia; Situmorang, T.D., Division of Nephrology, Department of Internal Medicine, PGI Cikini Hospital, Jakarta, 10330, Indonesia; Delliana, J., Department of Cardiology, Directorate of Non-Communicable Disease, Ministry of Health - Republic of Indonesia, Jalan Percetakan Negara 29, Jakarta, 10560, Indonesia; Roesli, R.M.A., Department of Internal Medicine, Faculty of Medicine, Padjadjaran University, Hasan Sadikin General Hospital, Bandung, 40161, Indonesia; Danny, S.S., Department of Cardiology - Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia; Suhardjono, Division of Nephrology and Hypertension, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto, Mangunkusumo National General Hospital, Jalan Pangeran Diponegoro No: 71, Jakarta, 10430, Indonesia; Sofiatin, Y., Department of Public Health, Faculty of Medicine, Padjadjaran University, Jalan Prof. Eijkman 38, Bandung, 40161, Indonesia; Hermiawaty, E., Department of Neurology, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia; Kuncoro, A.S., Department of Cardiology - Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia; Barack, R., Department of Cardiology, MMC Hospital, Jakarta, Indonesia; Beaney, T., Imperial Clinical Trials Unit, Imperial College London, Stadium House, 68 Wood Lane, Shepherd's Bush, London, W12 7RH, United Kingdom, Department of Primary Care and Public Health, Imperial College London, St Dunstan's Road, London, W6 8RP, United Kingdom; Ster, A.C., Imperial Clinical Trials Unit, Imperial College London, Stadium House, 68 Wood Lane, Shepherd's Bush, London, W12 7RH, United Kingdom; Poulter, N.R., Imperial Clinical Trials Unit, Imperial College London, Stadium House, 68 Wood Lane, Shepherd's Bush, London, W12 7RH, United Kingdom; Santoso, A., Department of Cardiology - Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia |
Elevated blood pressure (BP) is a significant burden worldwide, leading to high cardiocerebro-reno-vascular morbidity and mortality. For the second year of the May Measurement Month (MMM) campaign in Indonesia in 2018, we recruited 174 sites in 31 out of 34 provinces in Indonesia and screened through convenience sampling in public areas and rural primary health centres. Hypertension was defined as systolic BP ≥140 mmHg or diastolic BP ≥90 mmHg, or both, or on the basis of receiving antihypertensive medication. Blood pressure was measured three times followed the standard global MMM protocol, multiple imputation was used to estimate the mean of the 2nd and 3rd BP readings if these were not recorded. A total of 91 222 individuals were screened, and after multiple imputations, 27 331 (30.0%) had hypertension. Of individuals not receiving antihypertensive medication, 14 367 (18.4%) were hypertensive. Among the 47.4% of hypertensive individuals on antihypertensive medication, 10 106 (78.0%) had uncontrolled BP. MMM17 and MMM18 were still the most extensive standardized screening campaigns for BP measurement in Indonesia. Compared to the previous study, the proportion with uncontrolled BP on medication was significantly higher and provided the substantial challenges in managing hypertension in the rural community. © The Author(s) 2020. |
Blood pressure; Community; Control; Hypertension; Screening |
antihypertensive agent; adult; antihypertensive therapy; Article; blood pressure measurement; controlled study; cross-sectional study; female; human; hypertension; hypertensive patient; Indonesia; major clinical study; male; primary health care; priority journal; rural population |
Oxford University Press |
1520765X |
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Article |
Q3 |
389 |
12388 |
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872 |
Irawati Y., Priscilia F., Zakiyah H. |
57201260313;57222057383;57222068709; |
Orbital compressed air and diesel explosion injury resembling orbital cellulitis: An unusual case |
2021 |
American Journal of Case Reports |
22 |
1 |
e929671 |
1 |
5 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101275391&doi=10.12659%2fAJCR.929671&partnerID=40&md5=80fd24f7f41fb31a24ce6feb9c9c1db4 |
Division of Plastic and Reconstructive Surgery, Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Ophthalmology, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Irawati, Y., Division of Plastic and Reconstructive Surgery, Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Priscilia, F., Department of Ophthalmology, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Zakiyah, H., Department of Ophthalmology, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Objective: Background: Case Report: Conclusions: Unusual clinical course In this observational case report, we describe a case of orbital cellulitis caused by blunt trauma from an orbital compressed air and diesel explosion injury. A 44-year-old man presented to our emergency department with a marked clinical worsening of right upper eyelid swelling, accompanied by pain, fever, and redness. Four days prior, the patient’s right eye was struck by a pressurized diesel engine explosion. He sought treatment at another hospital, where an initial examination was conducted and a small laceration was found and immediately treated with irrigation and medication. The wound became progressively worse, and on examination at our hospital, we diagnosed orbital cellulitis, multiple abscesses, and pneumo-orbital formations. There was no indication of infection from the ears, nose, throat, and oral cavity, which usually causes orbital cellulitis. Drainage, debridement, incision, and necrotomy with orbital decompression (canthotomy and cantholysis procedure) was then performed on the patient. Diesel explosion injury can cause orbital cellulitis which can appear to be a simple case at first but has a poor prognosis. Therefore, evaluating the patient’s trauma history, computed tomography scan, and histopathological examination are essential in establishing the diagnosis. As early as possible, a diagnosis should be made to prevent tissue damage due to inflammation. Surgical debridement and the administration of a corticosteroid and antibiotic were key to managing the presented case. © Am J Case Rep, 2021. |
Compressed Air; Explosions; Orbital Diseases |
amoxicillin plus clavulanic acid; artificial tear; C reactive protein; chloramphenicol; diclofenac; diesel fuel; eye drops; levofloxacin; methylprednisolone; metronidazole; omeprazole; potassium hydroxide; prednisolone acetate; sodium chloride; sultamicillin; thymol; abscess; adult; antibiotic sensitivity; Article; bacterium culture; blast injury; cantholysis; canthotomy; case report; chemosis; clinical article; clinical feature; compressed air; computer assisted tomography; conjunctival hemorrhage; conjunctival hyperemia; debridement; decompression surgery; diesel engine; disease exacerbation; disease severity; emergency ward; exophthalmos; eye edema; eye examination; eye lavage; eye pain; eye redness; eye surgery; eye swelling; eyelid disease; fever; follow up; Gram positive bacterium; h |
International Scientific Information, Inc. |
19415923 |
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33611333 |
Article |
Q3 |
247 |
16822 |
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876 |
Sari I.P., Audindra S., Zhafira A.S., Rahma A.A., Syarira C.V., Wahdini S. |
57197543698;57222006228;57205515532;57222005612;57222010715;57203684068; |
Nutritional status of school-aged children with intestinal parasite infection in South Jakarta, Indonesia |
2021 |
Open Access Macedonian Journal of Medical Sciences |
9 |
E |
|
95 |
100 |
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3 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100938719&doi=10.3889%2foamjms.2021.5711&partnerID=40&md5=1772780d39afba8ba66dd65e8997f0b4 |
Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Undergraduate Program in Medical Doctor, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Sari, I.P., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Audindra, S., Undergraduate Program in Medical Doctor, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Zhafira, A.S., Undergraduate Program in Medical Doctor, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Rahma, A.A., Undergraduate Program in Medical Doctor, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Syarira, C.V., Undergraduate Program in Medical Doctor, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Wahdini, S., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
BACKGROUND: The prevalence of intestinal parasitic infection still high in Indonesia and lead to nutritional disorder, especially in the school-aged children. AIM: This research conducted to find the association of intestinal parasitic infection to the nutritional status of the children. METHODS: This was a cross sectional study, conducted in January 2016 in one primary school in South Jakarta, Jakarta, Indonesia, by collecting the children’s stool from 1st to 5th grade. Direct examination of the stool was conducted in the Parasitology Department, Faculty of Medicine, Universitas Indonesia, by Lugol and eosin staining. Nutritional status categorized using BMI chart. Data were analyzed using Chi-square test, Statistical Product, and Service Solutions version 20. RESULTS: From the total 157 stool examined in the laboratory, there were 60 (38.2%) children positively infected with various kinds of intestinal parasites. Mostly the infection is caused by Blastocystis hominis, which infects 44 children (69.4%). The other infection is caused by Giardia lamblia (15.3%), Trichuris trichiura (1.4%), and hookworm (1.4%), and mixed infection of B. hominis and Escherichia coli (4.2%) and B. hominis with G. lamblia (4.2%). From the total of infected children, 17 children (28.3%) have BMI below 5th percentile, and it was considered as malnourished. Moreover, 67 uninfected children have normal nutritional status. Statistically, there is an association between intestinal parasitic infection and nutritional status in school-aged children in South Jakarta (P < 0.05). CONCLUSION: The incidence of intestinal parasitic infection in school-aged children is 38.2%. Moreover, 28.3% of the infected children were malnourished and it is suggested that children with intestinal parasite infection have low nutritional status. © 2021 Ika Puspa Sari, Sacha Audindra, Aqila S. Zhafira, Arin A. Rahma, Cut V. Syarira, Sri Wahdini. |
Malnourish; Parasitic Infection; Primary Schools; South Jakarta |
Article; Blastocystis hominis; body mass; child; cross-sectional study; disease association; Escherichia coli; feces analysis; female; Giardia intestinalis; human; Indonesia; intestine parasite; major clinical study; male; malnutrition; mixed infection; nutritional status; obesity; parasitosis; prevalence; primary school; questionnaire; seasonal variation; Trichuris trichiura; underweight |
Open Access Macedonian Journal of Medical Sciences |
18579655 |
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Article |
Q3 |
288 |
15252 |
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878 |
Sitohang I.B.S., Rheza A.M., Sirait S.P., Fitri E.M., Suseno L.S. |
56734569200;57221927642;56426927400;57221929310;57202804092; |
Acne Vulgaris Mimicking Cutaneous Lupus Erythematosus in an Adolescent: Report of a Rare Case |
2021 |
Case Reports in Dermatology |
13 |
1 |
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69 |
74 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100667271&doi=10.1159%2f000511530&partnerID=40&md5=e670f0805c017b254cadf2cd24514e56 |
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia |
Sitohang, I.B.S., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Rheza, A.M., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Sirait, S.P., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Fitri, E.M., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Suseno, L.S., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia |
Acne vulgaris is a chronic and self-limiting disorder of the pilosebaceous unit which is primarily seen in adolescents. Acne vulgaris presents as polymorphic lesions, consisting of comedones, papules, pustules, cysts, nodules, scarring, and dyspigmentation. Acneiform presentation of cutaneous lupus erythematosus (CLE) is extremely rare. The presentation of CLE is notoriously diverse and often mimics a broad range of unrelated skin disorders. We present a case by referring to American College of Rheumatology (ACR) criteria for systemic lupus erythematosus (SLE); our patient's conditions did not meet any of the clinical criteria of the Systemic Lupus International Collaborating Clinics (SLICC) for SLE. Subsequent to thorough history-taking, physical examination, and laboratory evaluations, the diagnosis of acne vulgaris was established, and a diagnosis of CLE was excluded. As acneiform presentation of CLE is rare, we here present a case which resembled both acne vulgaris and CLE. We describe our experience in establishing the diagnosis of severe acne vulgaris accompanied by scars in a 12-year-old boy with a malar rash and scars on his frontal and malar area who had initially been misdiagnosed as having CLE. This unusual case highlights the broad spectrum of adolescent acne and the importance of clinical identification of the disease so that unnecessary workups might be avoided. © 2021 |
Adolescent; Cutaneous lupus erythematosus; Severe acne vulgaris |
2 hydroxyacid; antinuclear antibody; benzoyl peroxide; clindamycin; complement component C3; glycolic acid; retinoic acid; triamcinolone acetonide; acne; acne vulgaris; adolescent; Article; brain spongiosis; case report; child; clinical article; comedo; diagnostic error; epiluminescence microscopy; erythema; follow up; histopathology; human; human tissue; hyperpigmentation; hypertrophic scar; immunofluorescence; male; papule; physical examination; pustule; rash; scar; school child; skin biopsy; skin defect; skin lupus erythematosus; systemic lupus erythematosus; urinalysis |
S. Karger AG |
16626567 |
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Article |
Q3 |
338 |
13690 |
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