Publikasi Scopus FKUI Terkait Covid-19 Update 13 Desember 2021

Simadibrata D.M., Pandhita B.A.W., Ananta M.E., Tango T.
57202134322;57202730391;57219709130;57216890262;
Platelet-to-lymphocyte ratio, a novel biomarker to predict the severity of COVID-19 patients: A systematic review and meta-analysis
2022
Journal of the Intensive Care Society
23
1
20
26
4
Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia
Simadibrata, D.M., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Pandhita, B.A.W., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Ananta, M.E., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Tango, T., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia
Platelet-to-lymphocyte ratio (PLR), a novel inflammatory marker, has been suggested to predict the severity of COVID-19 patients. This systematic review aims to evaluate the association between PLR levels on admission and the severity of COVID-19 patients. A systematic literature search was done on 23 July 2020 to identify peer-reviewed studies, preprints, and grey literatures. Research articles comparing the PLR value on admission in adult patients with COVID-19 with varying degrees of severity were included in the analysis. The following keywords were used for the search: “COVID-19”, “PLR”, “severity”, and “mortality”. A total of seven studies were included in the meta-analysis, six of which were conducted in China. From a total of 998 participants included, 316 (31.7%) had severe diseases; and those in the severe group were generally older and had underlying diseases compared to the non-severe group. In comparison to non-severe patients, the meta-analysis showed that severe COVID-19 patients had higher PLR levels on admission (SMD 0.68; 95%CI 0.43-0.93; I2 =58%). High PLR levels on admission were associated with severe COVID-19 cases. Therefore, the on-admission PLR level is a novel, cost-effective, and readily available biomarker with a promising prognostic role for determining the severity of COVID-19 patients. © The Intensive Care Society 2020.
coronavirus; COVID-19; Platelet-to-lymphocyte ratio; SARS-CoV-2; severity
SAGE Publications Inc.
17511437
Article
Q2
551
9167