Publikasi Scopus 2023 per tanggal 31 Januari 2023 (41 artikel)

Authors

Giantini A., Suhaeri M., Kusumaningrum A., Prasetyo D.S., Sahar W., Hidayat R., Putra M.A., Hermawan

Author S Id

12776781400;56183087500;57211641695;57465206900;57224929934;57225289998;57215605850;58021815500;

Title

Evaluation of loop-mediated isothermal amplification for detecting COVID-19

Year

2023

Source Title

Journal of Clinical Virology Plus

Volume

Issue

Art No

100132

Page Start

Page End

Page Count

Cited By

Link

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85146022198&doi=10.1016%2fj.jcvp.2022.100132&partnerID=40&md5=39d2af0cec0ec37e6c1b38129cb761c5

Affiliations

Universitas Indonesia Hospital, Universitas Indonesia, Depok, 16424, Indonesia; Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Unit of Education, Research, and Training, Universitas Indonesia Hospital, Universitas Indonesia, Depok, 16424, Indonesia; Biomolecular Laboratory, Universitas Indonesia Hospital, Universitas Indonesia, Depok, 16424, Indonesia; Medical Service Unit, Universitas Indonesia Hospital, Universitas Indonesia, Depok, 16424, Indonesia

Authors With Affiliations

Giantini, A., Universitas Indonesia Hospital, Universitas Indonesia, Depok, 16424, Indonesia, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Suhaeri, M., Unit of Education, Research, and Training, Universitas Indonesia Hospital, Universitas Indonesia, Depok, 16424, Indonesia; Kusumaningrum, A., Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Biomolecular Laboratory, Universitas Indonesia Hospital, Universitas Indonesia, Depok, 16424, Indonesia; Prasetyo, D.S., Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Biomolecular Laboratory, Universitas Indonesia Hospital, Universitas Indonesia, Depok, 16424, Indonesia, ; Sahar, W., Unit of Education, Research, and Training, Universitas Indonesia Hospital, Universitas Indonesia, Depok, 16424, Indonesia; Hidayat, R., Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Medical Service Unit, Universitas Indonesia Hospital, Universitas Indonesia, Depok, 16424, Indonesia; Putra, M.A., Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Medical Service Unit, Universitas Indonesia Hospital, Universitas Indonesia, Depok, 16424, Indonesia; Hermawan, Medical Service Unit, Universitas Indonesia Hospital, Universitas Indonesia, Depok, 16424, Indonesia

Abstract

The emergence of SARS-CoV-2 has caused worldwide pandemic of COVID-19. Infection is difficult to diagnose early as some patients remain asymptomatic and may carry this virus to other people. Currently, qRT-PCR is the widely accepted mode for detection. However, the need for sophisticated instrument and trained personnel may hinder its application, especially in remote and facility-lacking areas. Reverse transcription loop-mediated isothermal amplification (RT-LAMP) may serve as a potential approach for detection of SARS-CoV-2 as the resources needed in its application is far less complex than those of qRT-PCR. Herein, we evaluated RT-LAMP based analytical method (COVIDNow), relative to qRT-PCR, in detecting SARS-CoV-2 by using 63 clinical respiratory samples. Based on our finding, COVIDNow exhibited sensitivity and specificity values of 87.5% and 80.6%, respectively. Taken together, RT-LAMP based detection of SARS-CoV-2 by utilizing COVIDNow might serves as a valuable diagnostic tool in the management of global COVID-19 pandemic condition. © 2022 The Author(s)

Author Keywords

COVID-19; Diagnosis; qRT-PCR; RT-LAMP; SARS-CoV-2

Index Keywords

Funding Details

Funding Text 1

We thank PT Nusantara Berkat Cipta in providing this work with the COVIDNow diagnostic tool. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

Funding Text 2

Funding Text 3

Publisher

Elsevier Ltd

Issn

26670380

Isbn

Pubmed Id

Document Type

Article

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