Publikasi Scopus FKUI Tahun 2010 s/d 2020 (data Per 3 Februari 2021)

3181

Authors_Last_Name

Arline Diana I., Gondokaryono S.P., Lestari Sugito T., Devita Lokanata M., Agustin T., Rahmayunita G., Maharani I., Shoraya N., Toyoshima H., Agung Yunaidi D.

Author S Id

57210441107;20733837500;57219652329;57219659842;57192918767;57192909174;57219659624;57219652013;57202927309;57219660989;

Title

A randomized, controlled, cross-over study of the safety and efficacy of super-absorbent diaper for babies with mild-to-moderate diaper rash

Year

2020

Source Title

Medical Journal of Indonesia

Volume

Issue

Art No

Page Start

283

Page End

289

Page Count

Cited By

Link

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85094614315&doi=10.13181%2fmji.oa.203630&partnerID=40&md5=2d58d251d797ef15953b3b66738db2e9

Affiliations

Indonesian Pediatric Dermatology Study Group, Indonesian Society of Dermatology and VenereologyJakarta, Indonesia; Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran Hasan Sadikin Hospital, Bandung, Indonesia; Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia Cipto Mangunkusumo HospitalJakarta, Indonesia; Dermatovenereology Medical Unit, Harapan Kita Women and Children HospitalJakarta, Indonesia; KAO Corporation, Tochigi, Japan; PT Equilab InternationalJakarta, Indonesia; Indonesian Society of Dermatology and Venereology (PERDOSKI), Jalan Salemba 1 No. 22, Kenari, Senen, Central Jakarta, 10430, Indonesia

Authors With Affiliations

Arline Diana, I., Indonesian Pediatric Dermatology Study Group, Indonesian Society of Dermatology and VenereologyJakarta, Indonesia, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran Hasan Sadikin Hospital, Bandung, Indonesia; Gondokaryono, S.P., Indonesian Pediatric Dermatology Study Group, Indonesian Society of Dermatology and VenereologyJakarta, Indonesia, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran Hasan Sadikin Hospital, Bandung, Indonesia, Indonesian Society of Dermatology and Venereology (PERDOSKI), Jalan Salemba 1 No. 22, Kenari, Senen, Central Jakarta, 10430, Indonesia; Lestari Sugito, T., Indonesian Pediatric Dermatology Study Group, Indonesian Society of Dermatology and VenereologyJakarta, Indonesia; Devita Lokanata, M., Indonesian Pediatric Dermatology Study Group, Indonesian Society of Dermatology and VenereologyJakarta, Indonesia; Agustin, T., Indonesian Pediatric Dermatology Study Group, Indonesian Society of Dermatology and VenereologyJakarta, Indonesia, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia Cipto Mangunkusumo HospitalJakarta, Indonesia; Rahmayunita, G., Indonesian Pediatric Dermatology Study Group, Indonesian Society of Dermatology and VenereologyJakarta, Indonesia, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia Cipto Mangunkusumo HospitalJakarta, Indonesia; Maharani, I., Indonesian Pediatric Dermatology Study Group, Indonesian Society of Dermatology and VenereologyJakarta, Indonesia; Shoraya, N., Indonesian Pediatric Dermatology Study Group, Indonesian Society of Dermatology and VenereologyJakarta, Indonesia, Dermatovenereology Medical Unit, Harapan Kita Women and Children HospitalJakarta, Indonesia; Toyoshima, H., KAO Corporation, Tochigi, Japan; Agung Yunaidi, D., PT Equilab InternationalJakarta, Indonesia

Abstract

BACKGROUND Super-absorbent diaper is a disposable diaper with new technology which has a soft-airy structure, breathable sheet, and rich absorbent core. This study aimed to compare the safety and efficacy of super-absorbent diaper with standard absorbent diaper. METHODS A single-blinded, randomized, controlled, cross-over study was performed in 3–24 months babies. A safety study was performed in 113 babies without diaper rash (group A: Super-absorbent to standard and B: Standard to super-absorbent) and efficacy study in 59 babies with mild-to-moderate diaper rash (group C: Super-absorbent to standard and D: Standard to super-absorbent). Each group used super-absorbent or standard diaper for 2 weeks. Skin assessment scores (SAS) were recorded at baseline, week-2, and week-4. Non-parametric tests were used to analyze the data. RESULTS In the safety study, there was no significant increase of SAS in group A at week-2 and -4, but in group B there was a significant increase of SAS (1.9 to 4.1, p = 0.001) at week-2 with a significant reduction at week-4 (4.1 to 2.2, p<0.001). In the efficacy study, there was a reduction of SAS at week-2 in group C (p = 0.07) and D (p = 0.05). However, SAS increased in group C (6.4 to 8.3, p = 0.2) and decreased in group D (8.6 to 6.1, p = 0.13) at week-4. Super-absorbent diaper showed a significant reduction of SAS in the pubic areas (1.43 to 0.73, p<0.011). CONCLUSIONS The new super-absorbent diaper is safe to use and may have efficacy in the improvement of skin conditions and diaper rash, especially in the pubic areas. © 2020 Authors.

Author Keywords

Efficacy; Safety; Super-absorbent diaper

Index Keywords

absorbent; soap; Article; child; comparative study; controlled study; crossover procedure; desquamation; diaper dermatitis; disease severity; edema; efficacy parameters; erosion; erythema; female; human; infant; male; papule; pustule; randomized controlled trial; safety; skin defect

Publisher

Faculty of Medicine, Universitas Indonesia

Issn

08531773

Isbn

Coden

Pubmed Id

Document Type

Article

Sjr Best Quartile

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