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Publikasi Scopus 2024 per tanggal 31 Agustus 2024 (707 artikel)
Publikasi Scopus 2024 per tanggal 31 Agustus 2024 (707 artikel)
Gach, Michael W. (57675752100); Lazarus, Gilbert (57214599425); Simadibrata, Daniel Martin (57202134322); Sinto, Robert (36099377100); Saharman, Yulia Rosa (55980934300); Limato, Ralalicia (57196224631); Nelwan, Erni J. (14527452900); van Doorn, H. Rogier (56941604800); Karuniawati, Anis (54886816200); Hamers, Raph L. (23034345900)
Antimicrobial resistance among common bacterial pathogens in Indonesia: a systematic review
2024
The Lancet Regional Health - Southeast Asia
26
100414
0
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85192810137&doi=10.1016%2fj.lansea.2024.100414&partnerID=40&md5=8b7941694224b5ac273f8fd664e75b48
Oxford University Clinical Research Unit Indonesia, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, United States; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Department of Internal Medicine, Division of Tropical Medicine and Infectious Diseases, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Clinical Microbiology, Dr. Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Oxford University Clinical Research Unit, Hanoi, Viet Nam
Background: The WHO Global Antimicrobial Resistance Surveillance System (GLASS) aims to describe antimicrobial resistance (AMR) patterns and trends in common bacterial pathogens, but data remain limited in many low and middle-income countries including Indonesia. Methods: We systematically searched Embase, PubMed and Global Health Database and three Indonesian databases for original peer-reviewed articles in English and Indonesian, published between January 1, 2000 and May 25, 2023, that reported antimicrobial susceptibility for the 12 GLASS target pathogens from human samples. Pooled AMR prevalence estimates were calculated for relevant pathogen-antimicrobial combinations accounting for the sampling weights of the studies (PROSPERO: CRD42019155379). Findings: Of 2182 search hits, we included 102 papers, comprising 19,517 bacterial isolates from hospitals (13,647) and communities (5870). In hospital settings, 21.6% of Klebsiella pneumoniae isolates, 18.3% of Escherichia coli isolates, 35.8% of Pseudomonas aeruginosa isolates and 70.7% of Acinetobacter baumannii isolates were carbapenem-resistant; 29.9% of Streptococcus pneumoniae isolates were penicillin-resistant; and 22.2% of Staphylococcus aureus isolates were methicillin-resistant. Hospital prevalence of carbapenem-resistant K. pneumoniae and E. coli, and penicillin-resistant S. pneumoniae increased over time. In communities, 28.3% of K. pneumoniae isolates and 15.7% of E. coli isolates were carbapenem-resistant, 23.9% of S. pneumoniae isolates were penicillin-resistant, and 11.1% of S. aureus isolates were methicillin-resistant. Data were limited for the other pathogens. Interpretation: AMR prevalence estimates were high for critical gram-negative bacteria. However, data were insufficient to draw robust conclusions about the full contemporary AMR situation in Indonesia. Implementation of national AMR surveillance is a priority to address these gaps and inform context-specific interventions. Funding: Wellcome Africa Asia Programme Vietnam. © 2024 The Author(s)
amikacin; cefepime; cefoxitin; ceftazidime; cephalosporin; colistin; cotrimoxazole; doripenem; extended spectrum beta lactamase; fosfomycin; gentamicin; imipenem; meropenem; nitrofurantoin; oxacillin; piperacillin plus tazobactam; quinoline derived antiinfective agent; tigecycline; tobramycin; Acinetobacter baumannii; antibacterial activity; antibiotic resistance; antibiotic sensitivity; Article; bacterial load; bacterium isolation; carbapenem resistance; community acquired infection; disk diffusion; epsilometer test; Escherichia coli; geographic distribution; Haemophilus influenzae; hospital infection; human; Indonesia; infection risk; Klebsiella pneumoniae; matrix assisted laser desorption ionization time of flight mass spectrometry; meta analysis; methicillin resistance; methicillin res
Kementerian Pendidikan, Kebudayaan, Riset, dan Teknologi, MECRT; Oxford University Clinical Academic Graduate School, OUCAGS; OUCRU; JPT Family Trust; Ministry of Education, Culture, Research, and Technology Republic of Indonesia; Wellcome Africa Asia Programme Vietnam, (106680/Z/14/Z); Lembaga Pengelola Dana Pendidikan, LPDP, (202101182688); Lembaga Pengelola Dana Pendidikan, LPDP
Funding text 1: Wellcome Africa Asia Programme Vietnam.None. Funding statement: This work was funded by the Wellcome Africa Asia Programme Vietnam (106680/Z/14/Z), which also supports RLH and HRVD. MG was supported by the JPT Family Trust award and Oxford University Clinical Academic Graduate School. RL was supported by an OUCRU Prize Studentship and a Nuffield Dept of Medicine Tropical Network Fu
Elsevier Ltd
27723682
Article
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