Publikasi Scopus FKUI 2021 per tanggal 31 Agustus 2021 (582 artikel)

Maulani C., C Masulili S.L., Santoso W.D., Soedarsono N., Kusdhany L., Auerkari E.I.
57205060934;57226076327;6506080422;14049161500;55301180900;10139113000;
Association of subgingival Epstein-Barr virus and periodontitis
2021
F1000Research
10
414
Faculty of Dentistry, Universitas IndonesiaJakarta 10430, Indonesia; Department of Periodontology, Faculty of Dentistry, Universitas IndonesiaJakarta 10430, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas IndonesiaJakarta 10430, Indonesia; Department of Oral Biology, Faculty of Dentistry, Universitas IndonesiaJakarta 10430, Indonesia; Department of Prosthodontics, Faculty of Dentistry, Universitas IndonesiaJakarta 10430, Indonesia
Maulani, C., Faculty of Dentistry, Universitas IndonesiaJakarta 10430, Indonesia; C Masulili, S.L., Department of Periodontology, Faculty of Dentistry, Universitas IndonesiaJakarta 10430, Indonesia; Santoso, W.D., Department of Internal Medicine, Faculty of Medicine, Universitas IndonesiaJakarta 10430, Indonesia; Soedarsono, N., Department of Oral Biology, Faculty of Dentistry, Universitas IndonesiaJakarta 10430, Indonesia; Kusdhany, L., Department of Prosthodontics, Faculty of Dentistry, Universitas IndonesiaJakarta 10430, Indonesia; Auerkari, E.I., Department of Oral Biology, Faculty of Dentistry, Universitas IndonesiaJakarta 10430, Indonesia
Background: The Epstein-Barr virus (EBV) is gaining interest as a possible agent in the etiology of periodontitis. Previous studies have shown controversy on whether EBV DNA in the subgingival periodontal pockets is associated with periodontitis. The aim of the present study was to seek the potential relationship between EBV and periodontitis. Methods: Data on socio-demographics, oral health, and periodontal health were recorded, and samples were collected from gingival crevicular fluid, using sterile paper point. This case-control study of 118 participants included 59 subjects with severe periodontitis and 59 control subjects with mild periodontitis. The EBV load was determined by quantitative real-time PCR. Results: EBV DNA was detected in 37.3% of the case samples and in 18.6% of the control samples. There was no significant difference in the load of EBV DNA between severe and mild periodontitis (p>0.05). The observed load of EBV DNA was up to 4.55x10 5 copies/mL. The detected EBV DNA was significantly associated with the plaque index and the oral hygiene index (all p<0.05). Conclusions: A significant association was not found, but EBV might contribute to periodontitis. Gingival crevicular fluid is useful for monitoring the EBV load by the real-time PCR technique. Copyright: © 2021 Maulani C et al.
Epstein-Barr Virus; Gingival Crevicular Fluid; Periodontitis
virus DNA; case control study; complication; Epstein Barr virus; Epstein Barr virus infection; human; periodontitis; Case-Control Studies; DNA, Viral; Epstein-Barr Virus Infections; Herpesvirus 4, Human; Humans; Periodontitis
NLM (Medline)
20461402
34316360
Article
Q1
1099
3793