Publikasi Scopus FKUI 2021 per tanggal 31 Agustus 2021 (582 artikel)

Loho T., Widodo D.
55624513300;8231822900;
Rapid Antigen Detection Test for Severe Acute Respiratory Syndrome Coronavirus 2: How to Use It Properly?
2021
Acta medica Indonesiana
53
1
119
131
Department of Clinical Pathology, Faculty of Medicine, Universitas IndonesiaJakarta, Indonesia
Loho, T., Department of Clinical Pathology, Faculty of Medicine, Universitas IndonesiaJakarta, Indonesia; Widodo, D.
Cases of coronavirus disease 2019 (COVID-19) in Indonesia are still increasing and even higher in the last few weeks. Contact tracing and surveillance are important to locate cases in the community, including asymptomatic individuals. Diagnosis of COVID-19 depends on the detection of viral RNA, viral antigen, or indirectly, viral antibodies. Molecular diagnosis, using real time, reverse transcriptase polymerase chain reaction (RT-PCR), is the common standard method; however, it is not widely available in Indonesia and requires a high standard laboratory. Rapid, point-of-care antibody testing has been widely used as an alternative; however, interpretation of the results is not simple and now it is no longer used by the Indonesian government as a screening test for people travelling between locations. Thus, the rapid antigen detection test (Ag-RDT) is used by the Indonesian government as a screening test for travellers. As a result, many people buy the kit online and perform self-Ag-RDT at home. This raises the question of how safe and accurate it is to perform self-Ag-RDT at home. Before a test is applied, it is suggested to research its sensitivity and specificity, as compared to gold standard, and its limitations. In this article, laboratory diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is discussed, with an emphasis on Ag-RDT and the recommendation to use it properly in daily practice.
antigen testing; COVID-19; SARS-CoV-2
virus antibody; virus RNA; diagnosis; epidemiology; human; immunology; isolation and purification; physiology; prevention and control; procedures; reproducibility; sensitivity and specificity; Antibodies, Viral; COVID-19; COVID-19 Nucleic Acid Testing; COVID-19 Serological Testing; Humans; Reproducibility of Results; RNA, Viral; SARS-CoV-2; Sensitivity and Specificity
NLM (Medline)
1259326
33818415
Article
Q3
321
14162