Publikasi Scopus FKUI 2021 per tanggal 31 Agustus 2021 (582 artikel)

Rozaliyani A., Sedono R., Sjam R., Tugiran M., Adawiyah R., Setianingrum F., Jusuf A., Sungkar S., Hagen F., Meis J.F., Wahyuningsih R.
57203065912;56660590500;23398458200;57218291154;57208658742;57203061705;57205710194;57016857300;8050973500;55941779900;6507268400;
Molecular typing and antifungal susceptibility study of Aspergillus spp. In intensive care unit (ICU) patients in Indonesia
2021
Journal of Infection in Developing Countries
15
7
1014
1020
Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Anesthesiology, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia/Persahabatan Hospital, Jakarta, Indonesia; Department of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital (CWZ), Nijmegen, Netherlands; Department of Medical Mycology, Westerdijk Fungal Biodiversity Institute, Utrecht, Netherlands; Centre of Expertise in Mycology, Radboudumc/CWZ, Nijmegen, Netherlands; Department of Parasitology, Faculty of Medicine, Universitas Kristen, Jakarta, Indonesia
Rozaliyani, A., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Sedono, R., Department of Anesthesiology, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Sjam, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Tugiran, M., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Adawiyah, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Setianingrum, F., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Jusuf, A., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia/Persahabatan Hospital, Jakarta, Indonesia; Sungkar, S., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Hagen, F., Department of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital (CWZ), Nijmegen, Netherlands, Department of Medical Mycology, Westerdijk Fungal Biodiversity Institute, Utrecht, Netherlands; Meis, J.F., Department of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital (CWZ), Nijmegen, Netherlands, Centre of Expertise in Mycology, Radboudumc/CWZ, Nijmegen, Netherlands; Wahyuningsih, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Parasitology, Faculty of Medicine, Universitas Kristen, Jakarta, Indonesia
Introduction: Aspergillus exhibits a wide variation of susceptibility against antifungals according to genetic and environmental factors. Identification to the species level is necessary for appropriate treatment. Our objective was to determine the Aspergillus species involved in invasive pulmonary aspergillosis (IPA) among ICU patients in Jakarta, Indonesia. Methodology: The incidence of IPA in ICU patients at six hospitals in Jakarta from October 2012 - January 2015 was investigated. It involved a collection of endotracheal aspirates (ETA), nasal swabs and environmental samples around the hospitals, phenotypic screening, molecular characterization, and antifungal susceptibility testing. Results: Of the 405 patients investigated, 31 patients (7.7%) were diagnosed with putative IPA, from whom 45 Aspergillus isolates were collected. Aspergillus isolates were identified from pulmonary secretions in 24 patients, from nasal swabs in 7 patients and from both pulmonary secretions and nasal swabs in 7 patients. The phenotypic method showed 33 isolates of Aspergillus flavus (73.4%), nine Aspergillus fumigatus (20%), two Aspergillus niger (4.4%), and one Aspergillus nidulans (2.2%) isolate. Molecular identification showed 27 isolates of A. flavus (60.0%), eight isolates of A. fumigatus (17.8%), two isolates of A. niger (4.4%) and one isolate of A. nidulans (2.2%), while seven isolates (15.6%) were cryptic species or mixed isolates. Conclusions: Susceptibility testing showed all isolates were susceptible to amphotericin B, azoles and micafungin. Aspergillus flavus was the main causative organism in IPA cases in Jakarta, followed by A. fumigatus. © 2021 Journal of Infection in Developing Countries. All rights reserved.
Aspergillus; Molecular typing; Susceptibility
amphotericin B; internal transcribed spacer; isavuconazole; itraconazole; micafungin; microsatellite DNA; posaconazole; pyrrole; voriconazole; antifungal susceptibility; Article; Aspergillus; Aspergillus flavus; Aspergillus nidulans; Aspergillus niger; Aspergillus tamarii; cohort analysis; controlled study; fungus identification; human; incidence; Indonesia; intensive care unit; invasive aspergillosis; major clinical study; minimum effective concentration; minimum inhibitory concentration; multicenter study; nonhuman; Penicillium citrinum; phenotype; prospective study
Journal of Infection in Developing Countries
20366590
Article
Q3
322
14136