National Key Research and Development Program of China, NKRDPC; Ministry of Science and Technology, China Medical University; Conselho Nacional de Desenvolvimento Científico e Tecnológico, CNPq; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, CAPES; Xinjiang Science and Technology Supported; Hebei University of Chinese Medicine, HUCM; China Medical University, CMU; Asian University; Ministry of Higher Education, Malaysia, MOHE; National Natural Science Foundation of China, NSFC; Uni