Publikasi Scopus 926 artikel (Per 14 Maret 2022)

Sepsis contributes to significant mortality and morbidity in children. Despite rigorous resusci-tation effort, adequate antibiotics and advanced medical support, a significant proportion still face mortality due to multiple organ failure. Re-. cent hypothesis suggests host’s immune response pathology in the form of compensatory anti-in-flammatory response syndrome (CARS). This review aims to elucidate the pathophysiology of immune paralysis, both affecting innate and acquired immunity. © 2021, The Indonesian Foundation of Critical Care Medicine. All rights reserved.