Publikasi Scopus 926 artikel (Per 14 Maret 2022)

Ramlan A.A.W., Ratnaningrum A., Marsaban A.H.M.
57195941841;57223018172;57195383833;
A randomized controlled trial of infraorbital block using ketamine 1% for intra-and postoperative analgesia in children for ambulatory cleft lip correction
2021
Medical Journal of Indonesia
30
1
33
38
Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Anesthesiology, Fatmawati General Hospital, Jakarta, Indonesia
Ramlan, A.A.W., Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Ratnaningrum, A., Department of Anesthesiology, Fatmawati General Hospital, Jakarta, Indonesia; Marsaban, A.H.M., Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia
BACKGROUND In Indonesia, cleft lip correction surgery is often done as a social program in remote areas with limited resources. This study aimed to assess the effectiveness of ketamine, a cheaper and more accessible alternative, as a local analgesia in infraorbital block and to determine the possibility of ketamine as an alternative local analgesic drug for intraoperative and postoperative periods. METHODS This was a randomized controlled trial in children aged 2 months to 5 years who underwent cleft lip correction surgery at Cipto Mangunkusumo Hospital in 2016. Subjects were randomly divided into two groups: ketamine and bupivacaine. Standard general anesthesia with endotracheal intubation was performed in each group. Bilateral intraoral infraorbital block was performed using ketamine 1% 0.5 ml or bupivacaine 0.25% 0.5 ml. Postoperative evaluation includes pain scores based on the face, leg, activity, cry, and consolability (FLACC) scale and analgesic duration. RESULTS A total of 36 subjects were enrolled in this study, with 18 in each group. Both groups received the same total amount of fentanyl addition intraoperatively (p = 1). The postoperative FLACC pain scale scores between the two groups were not different, with p>0.05 in every measurement. The mean duration of postoperative analgesia in the ketamine group was longer than the bupivacaine group (15–13.49 hours, p = 0.031). CONCLUSIONS Infraorbital block with 1% ketamine 0.5 mg/kg was similarly effective for intraoperative and postoperative analgesia but had a longer duration than that with 0.25% bupivacaine 0.5 ml in ambulatory cleft lip correction. © 2021 Authors.
Cleft lip; Ketamine; Postoperative pain
bupivacaine; epinephrine; fentanyl; ketamine; paracetamol; sevoflurane; Article; breathing rate; child; cleft lip; cleft palate; clinical article; controlled study; endotracheal intubation; female; FLACC scale; follow up; general anesthesia; hemodynamics; human; infant; infraorbital nerve; infraorbital nerve block; intraoperative period; male; nerve block; pain assessment; postoperative analgesia; postoperative pain; pulse rate; randomized controlled trial; single blind procedure; telephone interview; visual analog scale
Faculty of Medicine, Universitas Indonesia
08531773
Article
Q4
164
21905