Publikasi Scopus 926 artikel (Per 14 Maret 2022)

Harimurti K., Saldi S.R.F., Dewiasty E., Alfarizi T., Dharmayuli M., Khoeri M.M., Paramaiswari W.T., Salsabila K., Tafroji W., Halim C., Jiang Q., Gamil A., Safari D.
23473513200;55201904000;55257705500;57221853325;57221841113;55994827400;57221097580;57192272141;57118271600;57221850899;36028184700;57202388319;23493586700;
Streptococcus pneumoniae carriage and antibiotic susceptibility among Indonesian pilgrims during the Hajj pilgrimage in 2015
2021
PLoS ONE
16
1 January
e0246122
Clinical Epidemiology and Evidence-Based Medicine (CEEBM) Unit, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Internal Medicine, Faculty of Medicine Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Center of Hajj Health, Ministry of Health, Jakarta, Indonesia; Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Pfizer Indonesia, Jakarta, Indonesia; Pfizer Inc., Collegeville, PA, United States; Pfizer Inc., Emerging Markets Medical and Scientific Affairs, Dubai, United Arab Emirates
Harimurti, K., Clinical Epidemiology and Evidence-Based Medicine (CEEBM) Unit, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Saldi, S.R.F., Clinical Epidemiology and Evidence-Based Medicine (CEEBM) Unit, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Dewiasty, E., Clinical Epidemiology and Evidence-Based Medicine (CEEBM) Unit, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Alfarizi, T., Center of Hajj Health, Ministry of Health, Jakarta, Indonesia; Dharmayuli, M., Center of Hajj Health, Ministry of Health, Jakarta, Indonesia; Khoeri, M.M., Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Paramaiswari, W.T., Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Salsabila, K., Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Tafroji, W., Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Halim, C., Pfizer Indonesia, Jakarta, Indonesia; Jiang, Q., Pfizer Inc., Collegeville, PA, United States; Gamil, A., Pfizer Inc., Emerging Markets Medical and Scientific Affairs, Dubai, United Arab Emirates; Safari, D., Eijkman Institute for Molecular Biology, Jakarta, Indonesia
The Hajj is an annual pilgrimage to Mecca and one of the largest gathering of people in the world. Most Indonesian pilgrims are senior adults and elderly adults, who are more prone to acquire infections during the Hajj ritual. The aims of this study are to investigate the dynamics of Streptococcus pneumoniae colonization and to investigate antibiotic susceptibility of pneumococcal strains in Indonesian pilgrims. This was a prospective multi-site longitudinal study in Indonesian hajj pilgrims aged >18 years old in the year 2015. Nasopharyngeal swabs were collected from the same subject before departure and upon arrival at the airport. S. pneumoniae was identified using conventional and molecular approach, while antibiotic susceptibility was determined using a disk diffusion method. Among 813 Hajj pilgrims who were enrolled from five sites in this study, the prevalence of S. pneumoniae carriage rates before- and after-the Hajj were 8.6% (95% CI 6.7–10.5%) and 8.2% (95% CI 6.4–10.1%), (p value: 0.844) respectively. Serotype 16F, 6A/6B, 3, 18, and 23F were the five most prevalent serotypes before Hajj, whereas serotypes 3, 34, 13, 4, and 23F were the most prevalent serotypes after Hajj. Serotype 3 was identified as most acquired serotype during Hajj in Indonesian pilgrim. There was an increase in the percentage of isolates susceptible to co-trimoxazole after Hajj (42.9% versus 57.4%). The study provided an overview of the change of dynamics of S. pneumoniae serotype acquisition in Indonesian Hajj Pilgrims. Along with data of vaccination serotypes coverage and antimicrobial susceptibility, these findings may contribute to recommendation of vaccination and treatment policies in the future. © 2021 Harimurti et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
chloramphenicol; clindamycin; cotrimoxazole; erythromycin; penicillin derivative; tetracycline; antiinfective agent; adult; airport; antibiotic sensitivity; Article; bacterial colonization; bacterial strain; bacterium isolate; controlled study; disk diffusion; female; human; Indonesian; longitudinal study; male; nasopharyngeal swab; nonhuman; prospective study; serotype; Streptococcus pneumoniae; adolescent; antibiotic resistance; clinical trial; crowding (area); growth, development and aging; heterozygote; Indonesia; isolation and purification; microbial sensitivity test; microbiology; middle aged; multicenter study; nasopharynx; pneumococcal infection; Streptococcus pneumoniae; Adolescent; Adult; Anti-Bacterial Agents; Carrier State; Crowding; Drug Resistance, Bacterial; Female; Humans;
Public Library of Science
19326203
33497410
Article
Q1
990
4434