No records
|
382 |
Vityadewi N., Bangun K., Budiman, Winarsih W., Fauzi A.R. |
57218771358;36902624600;57222390006;16053776500;57203133889; |
Correction to: Auricular cartilage regeneration on donor site defect with one-sided perichondrial cartilage graft in an experimental rabbit model (European Journal of Plastic Surgery, (2021), 44, 3, (307-314), 10.1007/s00238-020-01765-2) |
2021 |
European Journal of Plastic Surgery |
44 |
3 |
|
417 |
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102563175&doi=10.1007%2fs00238-021-01810-8&partnerID=40&md5=a522ad3fbe4e9f01f86ca4cc71a8915e |
Plastic, Reconstructive, and Aesthetic Surgery Division, Department of Surgery, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, 55281, Indonesia; Plastic, Reconstructive, and Aesthetic Surgery Division, Department of Surgery, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, 10430, Indonesia; Division of Plastic, Reconstructive, and Aesthetic Surgery, Department of Surgery, Gatot Subroto Army Hospital, Jakarta, Indonesia; Division of Pathology, Department of Veterinary Clinic Reproduction and Pathology, Bogor Agricultural University, Bogor, 16680, Indonesia |
Vityadewi, N., Plastic, Reconstructive, and Aesthetic Surgery Division, Department of Surgery, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, 55281, Indonesia; Bangun, K., Plastic, Reconstructive, and Aesthetic Surgery Division, Department of Surgery, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, 10430, Indonesia; Budiman, Division of Plastic, Reconstructive, and Aesthetic Surgery, Department of Surgery, Gatot Subroto Army Hospital, Jakarta, Indonesia; Winarsih, W., Division of Pathology, Department of Veterinary Clinic Reproduction and Pathology, Bogor Agricultural University, Bogor, 16680, Indonesia; Fauzi, A.R., Plastic, Reconstructive, and Aesthetic Surgery Division, Department of Surgery, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, 55281, Indonesia |
There is a leak in the name of Kristiania Bangun (The second author), and the correct name is “Kristaninta Bangun”. The original article has been corrected. © 2021, Springer-Verlag GmbH Germany, part of Springer Nature. |
|
erratum |
Springer Science and Business Media Deutschland GmbH |
0930343X |
|
|
Erratum |
Q3 |
219 |
18194 |
|
|
386 |
Oike T., Uchihara Y., Permata T.B.M., Gondhowiardjo S., Ohno T., Shibata A. |
36453136000;57221723636;57197808751;6508327402;35395665700;8323572900; |
Quantitative volumetric analysis of the Golgi apparatus following X-ray irradiation by super-resolution 3D-SIM microscopy |
2021 |
Medical Molecular Morphology |
54 |
2 |
|
166 |
172 |
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099941107&doi=10.1007%2fs00795-020-00277-z&partnerID=40&md5=67d2ba3ce4cc88d92e3e071747ee2f42 |
Department of Radiation Oncology, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma 371-8511, Japan; Gunma University Heavy Ion Medical Center, 3-39-22, Showa-machi, Maebashi, Gunma 371-8511, Japan; Signal Transduction Program, Gunma University Initiative for Advanced Research (GIAR), 3-39-22, Showa-machi, Maebashi, Gunma 371-8511, Japan; Department of Radiation Oncology, Faculty of Medicine Universitas Indonesia-Dr. Cipto Mangunkusumo Hospital, Jl. P. Diponegoro No. 71, Jakarta, 10430, Indonesia |
Oike, T., Department of Radiation Oncology, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma 371-8511, Japan, Gunma University Heavy Ion Medical Center, 3-39-22, Showa-machi, Maebashi, Gunma 371-8511, Japan; Uchihara, Y., Signal Transduction Program, Gunma University Initiative for Advanced Research (GIAR), 3-39-22, Showa-machi, Maebashi, Gunma 371-8511, Japan; Permata, T.B.M., Department of Radiation Oncology, Faculty of Medicine Universitas Indonesia-Dr. Cipto Mangunkusumo Hospital, Jl. P. Diponegoro No. 71, Jakarta, 10430, Indonesia; Gondhowiardjo, S., Department of Radiation Oncology, Faculty of Medicine Universitas Indonesia-Dr. Cipto Mangunkusumo Hospital, Jl. P. Diponegoro No. 71, Jakarta, 10430, Indonesia; Ohno, T., Department of Radiation Oncology, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma 371-8511, Japan, Gunma University Heavy Ion Medical Center, 3-39-22, Showa-machi, Maebashi, Gunma 371-8511, Japan; Shibata, A., Signal Transduction Program, Gunma University Initiative for Advanced Research (GIAR), 3-39-22, Showa-machi, Maebashi, Gunma 371-8511, Japan |
To obtain quantitative volumetric data for the Golgi apparatus after ionizing radiation (IR) using super-resolution three-dimensional structured illumination (3D-SIM) microscopy. Normal human retinal pigment epithelial (RPE) cells were irradiated with X-rays (10 Gy), followed by immunofluorescence staining of the Golgi marker RCAS1. 3D-SIM imaging was performed using DeltaVision OMX version 4 and SoftWoRx 6.1. Polygon rendering and spot signal identification were performed using Imaris 8.1.2. Differences between groups were assessed by Welch’s t test. RCAS1 signals in untreated cells were located adjacent to nuclei and showed a reticular morphology. Upon IR, the area of RCAS1 signals expanded while retaining the reticular morphology. Polygon rendering imaging revealed that the volume of RCAS1 at 48 h post-IR was greater than that for unirradiated cells (93.7 ± 19.0 μm3 vs. 33.0 ± 4.2 μm3, respectively; P < 0.001): a 2.8-fold increase. Spot signal imaging showed that the number of RCAS1 spot signals post-IR was greater than that for unirradiated cells [3.4 ± 0.8 (× 103) versus 1.3 ± 0.2 (× 103), respectively; P < 0.001]: a 2.7-fold increase. This is the first study to report quantitative volumetric data of the Golgi apparatus in response to IR using super-resolution 3D-SIM microscopy. © 2021, The Author(s). |
3D-SIM; Golgi; Ionizing radiation; RCAS1; Super-resolution microscopy |
article; controlled study; Golgi complex; human; human experiment; immunofluorescence; ionizing radiation; microscopy; quantitative analysis; retina pigment cell; signal transduction; vision; X irradiation; X ray; cell culture technique; epithelium cell; fluorescence microscopy; Golgi complex; procedures; radiation response; retina; three-dimensional imaging; ultrastructure; X ray; Cell Culture Techniques; Epithelial Cells; Golgi Apparatus; Humans; Imaging, Three-Dimensional; Microscopy, Fluorescence; Retina; X-Rays |
Springer Japan |
18601480 |
|
33501611 |
Article |
Q2 |
650 |
7736 |
|
|
387 |
Reksodiputro M.H., Hutauruk S.M., Widodo D.W., Fardizza F., Mutia D. |
35090488800;57205105620;56644646600;55091031700;57221630137; |
Platelet-Rich Fibrin Enhances Surgical Wound Healing in Total Laryngectomy |
2021 |
Facial Plastic Surgery |
37 |
3 |
|
325 |
332 |
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099660024&doi=10.1055%2fs-0040-1717083&partnerID=40&md5=43744ae74dd367876ae8b58289232fb6 |
Division of Facial Plastic Reconstructive, Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Dr. Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Division of Larynx Pharynx, Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Dr. Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Dr. Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia |
Reksodiputro, M.H., Division of Facial Plastic Reconstructive, Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Dr. Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Hutauruk, S.M., Division of Larynx Pharynx, Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Dr. Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Widodo, D.W., Division of Facial Plastic Reconstructive, Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Dr. Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Fardizza, F., Division of Larynx Pharynx, Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Dr. Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia; Mutia, D., Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Dr. Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta, Indonesia |
Autologous growth factor (AGF) is a cytokine that has gained medical research interest because it helps improve and accelerate the wound healing process. Platelet-rich fibrin (PRF) is the latest generation of platelet concentrate that can be obtained through a simple procedure known as AGF referencing. One of the most common complications of total laryngectomy (TL) is pharyngocutaneous fistula. To prevent this complication, health care providers must closely monitor the postoperative wound healing process.This study aimed to investigate the effectiveness of PRF application in enhancing wound healing after TL. A randomized controlled trial was conducted in the Department of Otorhinolaryngology - Head and Neck Surgery, Faculty of Medicine, Dr. Cipto Mangunkusumo Hospital Universitas Indonesia, Jakarta, Indonesia, from June 2019 to December 2019. We included 20 patients who underwent TL for laryngeal squamous cell carcinoma. They were divided into two groups (10 patients who received applied autologous PRF around the esophageal stoma during TL and another 10 patients as the control). These patients were observed for 2 weeks postoperatively. In the bivariate analysis performed using the chi-square test, the pain threshold and edema of postoperative wounds in the PRF-treated group demonstrated significant differences compared with those in the control group. PRF application in TL enhanced the postoperative wound healing process, especially with regard to edema and pain. © 2021 Thieme Medical Publishers, Inc.. All rights reserved. |
pharyngocutaneous fistula; platelet-rich fibrin; PRF; total laryngectomy |
platelet-rich fibrin; controlled study; human; laryngectomy; randomized controlled trial; surgical wound; wound healing; Humans; Laryngectomy; Platelet-Rich Fibrin; Surgical Wound; Wound Healing |
Thieme Medical Publishers, Inc. |
07366825 |
|
33445196 |
Article |
Q3 |
435 |
11329 |
|
|
388 |
Vityadewi N., Bangun K., Budiman, Winarsih W., Fauzi A.R. |
57218771358;36902624600;57222390006;16053776500;57203133889; |
Auricular cartilage regeneration on donor site defect with one-sided perichondrial cartilage graft in an experimental rabbit model |
2021 |
European Journal of Plastic Surgery |
44 |
3 |
|
307 |
314 |
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099103344&doi=10.1007%2fs00238-020-01765-2&partnerID=40&md5=584c9d67f1904c8e4053cf3ba2855fbe |
Plastic, Reconstructive and Aesthetic Surgery Division, Department of Surgery, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, 55281, Indonesia; Plastic Surgery Reconstruction and Aesthetics Division, Department of Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Division of Plastic Reconstructive Aesthetic Surgery, Department of Surgery, Gatot Subroto Army Hospital, Jakarta, Indonesia; Division of Pathology, Department of Veterinary Clinic Reproduction and Pathology, Bogor Agricultural University, Bogor, 16680, Indonesia |
Vityadewi, N., Plastic, Reconstructive and Aesthetic Surgery Division, Department of Surgery, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, 55281, Indonesia; Bangun, K., Plastic Surgery Reconstruction and Aesthetics Division, Department of Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Budiman, Division of Plastic Reconstructive Aesthetic Surgery, Department of Surgery, Gatot Subroto Army Hospital, Jakarta, Indonesia; Winarsih, W., Division of Pathology, Department of Veterinary Clinic Reproduction and Pathology, Bogor Agricultural University, Bogor, 16680, Indonesia; Fauzi, A.R., Plastic, Reconstructive and Aesthetic Surgery Division, Department of Surgery, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, 55281, Indonesia |
Background: Auricular cartilage is considered the source for cartilage grafts with good esthetic results and is often used in augmentation rhinoplasty. Most revision procedures require grafting, and the auricular cartilage can be the source for secondary rhinoplasty. Due to limited donor locations, donor site optimization of graft material is very important. We aimed to evaluate the healing process from the donor site, including the regeneration of cartilage from the donor site in an experimental animal model. Methods: Six New Zealand white rabbits were used for the investigation of cartilage regeneration from donor defects with one-sided perichondrium. Cartilage defect measuring 0.5 × 3 cm was made in rabbit ears. Two trial groups with 12 ears in each group were formed (one-sided perichondrium vs without perichondrium). Macroscopic and microscopic evaluation examinations were performed at week 4. The gap and thickness of the donor defect were measured with a centimeter grinder for macroscopic evaluation. Results: While macroscopic evaluation of wound thickness and the gap was not significant between groups (p = 1.00, p = 0.053, respectively), microscopic evaluation showed immature cartilage formation at week 4 of the donor defect with one-sided perichondrium (p = 0.004). Conclusions: The donor defect with one-sided perichondrium showed new cartilage formation within the area of the perichondrium. These findings showed the regeneration of cartilage was developed at the donor defects with one-sided perichondrium in the fourth week. Level of evidence: Not ratable. © 2021, Springer-Verlag GmbH Germany, part of Springer Nature. |
Auricular cartilage graft; Cartilage healing; Cartilage regeneration; Donor defect |
|
Springer Science and Business Media Deutschland GmbH |
0930343X |
|
|
Article |
Q3 |
219 |
18194 |
|
|
389 |
Bangun K., Sukasah C.L., Dilogo I.H., Indrani D.J., Siregar N.C., Pandelaki J., Iskandriati D., Kekalih A., Halim J. |
36902624600;57218391534;56161962800;6602774472;6508087790;35759266900;6507742011;55633562200;57219398869; |
Bone Growth Capacity of Human Umbilical Cord Mesenchymal Stem Cells and BMP-2 Seeded Into Hydroxyapatite/Chitosan/Gelatin Scaffold in Alveolar Cleft Defects: An Experimental Study in Goat |
2021 |
Cleft Palate-Craniofacial Journal |
58 |
6 |
|
707 |
717 |
|
1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85092575595&doi=10.1177%2f1055665620962360&partnerID=40&md5=a3280d360d1de28c8353dffc23d716b3 |
Department of Plastic and Reconstructive Surgery, Cleft and Craniofacial Center, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Unit Pelayanan Terpadu Teknologi Kedokteran Sel Punca (Stem Cell Research Center), Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Department of Dental Material Science and Technology, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia; Anatomical Pathology Department, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Radiology Department of Cipto, Mangunkusumo General Hospital, Jakarta, Indonesia; Primate Research Center of Bogor Agricultural Institute, Bogor, Indonesia; Community Medicine Department, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Bangun, K., Department of Plastic and Reconstructive Surgery, Cleft and Craniofacial Center, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Sukasah, C.L., Department of Plastic and Reconstructive Surgery, Cleft and Craniofacial Center, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Dilogo, I.H., Unit Pelayanan Terpadu Teknologi Kedokteran Sel Punca (Stem Cell Research Center), Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Indrani, D.J., Department of Dental Material Science and Technology, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia; Siregar, N.C., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Anatomical Pathology Department, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Pandelaki, J., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Radiology Department of Cipto, Mangunkusumo General Hospital, Jakarta, Indonesia; Iskandriati, D., Primate Research Center of Bogor Agricultural Institute, Bogor, Indonesia; Kekalih, A., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Community Medicine Department, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Halim, J., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Objective: To evaluate bone regeneration in alveolar defects treated with human umbilical cord–derived mesenchymal stem cells (hUCMSCs), hydroxyapatite/chitosan/gelatin (HA/CS/Gel) scaffold, and bone morphogenic protein-2 (BMP-2) in Capra hircus models. Design: Randomized posttest-only control group design. Setting: Animal Hospital at Bogor Agricultural Institute. Participants: Healthy and equally treated 24 female Capra hircus/goats. Intervention: Animals were randomly assigned to 3 experimental group design (iliac crest alveolar bone graft/ICABG [control], HA/Cs/Gel+BMP-2 [Novosys], and HA/Cs/Gel+BMP-2+UCMSCs). Graft materials were implanted in surgically made alveolar defects. Main Outcome Measures: Postoperative functional score and operating time were assessed. New bone growth, bone density, inflammatory cells recruitment, and neoangiogenesis were evaluated based on radiological and histological approach at 2 time points, week 4 and 12. Statistical analysis was done between treatment groups. Results: Operating time was 34% faster and functional score 94.5% more superior in HA/Cs/Gel+BMP-2+hUCMSC group. Bone growth capacity in HA/Cs/Gel+BMP-2+UCMSCs mimicked ICABG, but ICABG showed possibility of bone loss between week 4 and 12. The HA/Cs/Gel+BMP-2+UCMSCs showed early bone repopulation and unseen inflammatory cells and angiogenesis on week 12. Discussion and Conclusion: The HA/Cs/Gel+BMP-2+hUCMSCs were superior in enhancing new bone growth without donor site morbidity compared to ICABG. The presence of hUCMSCs in tissue-engineered alveolar bone graft (ABG), supported with paracrine activity of the resident stem cells, initiated earlier new bone repopulation, and completed faster bone regeneration. The HA/Cs/Gel scaffold seeded with UCMSCs+BMP-2 is a safe substitute of ICABG to close alveolar bone defects suitable for patients with cleft lip, alveolus, and palate. © American Cleft Palate-Craniofacial Association. All rights reserved 2020. |
alveolar bone grafts; bone regeneration; hydroxyapatite/chitosan/gelatin scaffold; iliac crest bone graft; mesenchymal stem cells; tissue engineering |
bone morphogenetic protein 2; chitosan; gelatin; hydroxyapatite; gelatin; hydroxyapatite; adult; alveolar bone; alveolar bone grafting; angiogenesis; animal experiment; animal model; animal tissue; Article; bone density; bone graft; bone growth; bone regeneration; controlled study; domestic goat; donor site; female; histology; human; human cell; iliac crest; inflammatory cell; jaw malformation; morbidity; nonhuman; operation duration; osteolysis; outcome assessment; paracrine signaling; umbilical cord mesenchymal stem cell; animal; bone development; goat; mesenchymal stem cell; tissue scaffold; umbilical cord; Animals; Bone Development; Bone Regeneration; Chitosan; Durapatite; Female; Gelatin; Goats; Humans; Mesenchymal Stem Cells; Tissue Scaffolds; Umbilical Cord |
SAGE Publications Ltd |
10556656 |
|
34047209 |
Article |
Q2 |
641 |
7859 |
|
|
390 |
Umbarawan Y., Enoura A., Ogura H., Sato T., Horikawa M., Ishii T., Sunaga H., Matsui H., Yokoyama T., Kawakami R., Maeno T., Setou M., Kurabayashi M., Iso T. |
57196077830;57224226756;57224226814;57202946030;57195494134;57224227073;55061468300;57212330485;7403358134;57210447153;35407637300;14326068500;7103371684;7003498756; |
Fabp5 is a sensitive marker for lipid-rich macrophages in the luminal side of atherosclerotic lesions |
2021 |
International Heart Journal |
62 |
3 |
|
666 |
676 |
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107318921&doi=10.1536%2fihj.20-676&partnerID=40&md5=50711618426db51f56d9cb4d728fc9ca |
Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan; Department of Internal Medicine, Faculty of Medicine Universitas IndonesiaJakarta, Indonesia; Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences, Maebashi, Japan; Department of Cellular and Molecular Anatomy, Hamamatsu University School of Medicine, Hamamatsu, Japan; International Mass Imaging Center, Hamamatsu University School of Medicine, Hamamatsu, Japan; Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, Hiroshima, Japan; Center for Liberal Arts and Sciences, Ashikaga University, Ashikaga, Japan; Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan; Department of Systems Molecular Anatomy, Institute for Medical Photonics Research, Preeminent Medical Photonics Education & Research Center, Hamamatsu, Japan |
Umbarawan, Y., Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan, Department of Internal Medicine, Faculty of Medicine Universitas IndonesiaJakarta, Indonesia; Enoura, A., Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences, Maebashi, Japan; Ogura, H., Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences, Maebashi, Japan; Sato, T., Department of Cellular and Molecular Anatomy, Hamamatsu University School of Medicine, Hamamatsu, Japan, International Mass Imaging Center, Hamamatsu University School of Medicine, Hamamatsu, Japan; Horikawa, M., Department of Cellular and Molecular Anatomy, Hamamatsu University School of Medicine, Hamamatsu, Japan, International Mass Imaging Center, Hamamatsu University School of Medicine, Hamamatsu, Japan, Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, Hiroshima, Japan; Ishii, T., Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences, Maebashi, Japan; Sunaga, H., Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan, Center for Liberal Arts and Sciences, Ashikaga University, Ashikaga, Japan; Matsui, H., Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences, Maebashi, Japan; Yokoyama, T., Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences, Maebashi, Japan; Kawakami, R., Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan; Maeno, T., Department of Allergy and Respiratory Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan; Setou, M., Department of Cellular and Molecular Anatomy, Hamamatsu University School of Medicine, Hamamatsu, Japan, International Mass Imaging Center, Hamamatsu University School of Medicine, Hamamatsu, Japan, Department of Systems Molecular Anatomy, Institute for Medical Photonics Research, Preeminent Medical Photonics Education & Research Center, Hamamatsu, Japan; Kurabayashi, M., Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan; Iso, T., Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan |
Lipid-rich macrophages in atherosclerotic lesions are thought to be derived from myeloid and vascular smooth muscle cells. A series of studies with genetic and pharmacological inhibition of fatty acid binding protein 4 (FABP4) and FABP5 and bone marrow transplant experiments with FABP4/5 deficient cells in mice have demonstrated that these play an important role in the development of atherosclerosis. However, it is still uncertain about the differential cell-type specificity and distribution between FABP4- and FABP5-expressing cells in early- and late-stage atherosclerotic lesions. In this study, we first explored spatial distribution of FABP4/5 in atherosclerotic lesions in apolipoprotein E deficient (ApoE-/-) mice. FABP4 was only marginally detected in early and advanced lesions, whereas FABP5 was abundantly expressed in these lesions. In advanced lesions, the FABP5-positive area was mostly restricted to the foam cell layer adjacent to the lumen above collagen and elastic fibers with a high signal/noise ratio. Oil red O (ORO) staining revealed that FABP5-positive cells were lipidrich in early and advanced lesions. Together, most of lipid-rich FABP5-positive cells reside adjacent to the lumen above collagen and elastic fibers. We next studied involvement of FABP5 in lesion formation of atherosclerosis using ApoE-/- FABP5-/- mice. However, deletion of FABP5 did not affect the development of atherosclerosis. These findings, along with previous reports, suggest a novel notion that FABP5 is a sensitive marker for bone marrow-derived lipid-rich macrophages in the luminal side of atherosclerotic lesions, although its functional significance remains elusive. © 2021, International Heart Journal Association. All rights reserved. |
Apolipoprotein E knockout mice; Atherosclerosis; Foam cell; Oil red O staining |
apolipoprotein E; CD68 antigen; collagen; fatty acid binding protein 4; fatty acid binding protein 5; Ki 67 antigen; Mac 3; smooth muscle actin; unclassified drug; Fabp4 protein, mouse; Fabp5 protein, mouse; fatty acid binding protein; tumor protein; adipogenesis; animal cell; animal experiment; animal model; animal tissue; apolipoprotein E knockout mouse; Article; atherosclerotic plaque; blood vessel wall; bone marrow transplantation; electrospray mass spectrometry; foam cell; image analysis; immunohistochemistry; lipid rich macrophage; lipid storage; macrophage; mouse; nonhuman; oil red O staining; signal noise ratio; staining; tissue preparation; vascular smooth muscle cell; animal; atherosclerosis; immunology; metabolism; Animals; Atherosclerosis; Fatty Acid-Binding Proteins; Foam Cell |
International Heart Journal Association |
13492365 |
|
33994513 |
Article |
Q2 |
555 |
9100 |
|
|
395 |
Dilogo I.H., Pawitan J.A., Tobing J.F.L., Fiolin J., Luviah E. |
56161962800;6508348067;36167767600;57194498274;56114966200; |
Amount of bone morphogenetic protein-2, epidermal growth factor, and vascular endothelial growth factor in adipose tissue, umbilical cord, and bone marrow mesenchymal stem cell derived secretome: An in-vitro study |
2021 |
Stem Cells in Disease Pathogenesis |
|
|
|
187 |
206 |
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114959444&partnerID=40&md5=456465470c35e0929cc2d9166da2405e |
Department of Orthopaedic and Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Indonesia; Department of Histology, Faculty of Medicine Universitas Indonesia, Indonesia; Stem Cell and Tissue Engineering Research Center, Indonesian Medical Education and Research Institute (IMERI), Universitas Indonesia, Indonesia |
Dilogo, I.H., Department of Orthopaedic and Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Indonesia; Pawitan, J.A., Department of Histology, Faculty of Medicine Universitas Indonesia, Indonesia; Tobing, J.F.L., Department of Orthopaedic and Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Indonesia; Fiolin, J., Department of Orthopaedic and Traumatology, Cipto Mangunkusumo Hospital, Faculty of Medicine Universitas Indonesia, Indonesia; Luviah, E., Stem Cell and Tissue Engineering Research Center, Indonesian Medical Education and Research Institute (IMERI), Universitas Indonesia, Indonesia |
[No abstract available] |
|
|
Nova Science Publishers, Inc. |
|
9781536196580; 9781536196306 |
|
Book Chapter |
#N/A |
#N/A |
#N/A |
|
|
396 |
Raharjo S.B., Chandranegara A.F., Hanafy D.A., Yamin M., Rasyid H.E., Haryadi, Rizal A., Ardhianto P., Hermanto D.Y., Yuniadi Y., OneAF Investigators |
57017880700;57224571328;55431326800;23475706300;57224560676;57224559936;57218771291;57208782791;57223816091;57155066100; |
Indonesian registry on atrial fibrillation (OneAF) |
2021 |
Medicine |
100 |
19 |
|
e25725 |
|
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107981983&doi=10.1097%2fMD.0000000000025725&partnerID=40&md5=c16e93c69fd23a59227c9462d518a9c8 |
Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center Harapan Kita; Pasar Rebo General Hospital; Department of Internal Medicine Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General HospitalJakarta, Indonesia; Department of Cardiology, Faculty of Medicine, alas University, Djamil General Hospital, Padang, West Sumatra, Indonesia; Eka Hospital, Pekanbaru, Riau, Indonesia; Department of Cardiology, Faculty of Medicine, Brawijaya University, Syaiful Anwar General Hospital, Malang, Indonesia; Department of Cardiology, Faculty of Medicine, Diponegoro University, Kariadi General Hospital, Semarang, Indonesia; Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center Harapan KitaJakarta, Indonesia |
Raharjo, S.B., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center Harapan Kita; Chandranegara, A.F., Pasar Rebo General Hospital; Hanafy, D.A., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center Harapan Kita; Yamin, M., Department of Internal Medicine Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General HospitalJakarta, Indonesia; Rasyid, H.E., Department of Cardiology, Faculty of Medicine, alas University, Djamil General Hospital, Padang, West Sumatra, Indonesia; Haryadi, Eka Hospital, Pekanbaru, Riau, Indonesia; Rizal, A., Department of Cardiology, Faculty of Medicine, Brawijaya University, Syaiful Anwar General Hospital, Malang, Indonesia; Ardhianto, P., Department of Cardiology, Faculty of Medicine, Diponegoro University, Kariadi General Hospital, Semarang, Indonesia; Hermanto, D.Y., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center Harapan KitaJakarta, Indonesia; Yuniadi, Y., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center Harapan KitaJakarta, Indonesia; OneAF Investigators |
BACKGROUND: Data on the optimal therapeutic international normalized ratio (INR) for non-valvular and valvular atrial fibrillation (AF) in Indonesia is currently unavailable. Therefore, we designed the Indonesian Registry on Atrial Fibrillation (OneAF) registry in order to seek a safe and beneficial range of INR in Indonesian patients with non-valvular and valvular AF. METHODS/DESIGN: The OneAF registry is a nationwide collaboration of the Indonesian Heart Rhythm Society (InaHRS) enrolling all hospitals with cardiac electrophysiologists in Indonesia. It is a prospective, multicentre, nationwide, observational study aiming to recruit non-valvular and valvular AF patients in Indonesia. The registry was started in January 2020 with a planned 2 years of recruitment. There are 2 respondents for this registry: non-cohort and cohort respondents. Non-cohort registry respondents are AF patients at hospitals who fulfill inclusion and exclusion criteria but did not consent for a 24 month follow up. Whereas patients who consented for a 24 month follow up were included as cohort registry respondents. Key data collected includes basic sociodemographic information, symptoms and signs, medical history, results of physical examination and laboratory test, details of diagnostics and treatment measures and events. RESULTS: Currently, a total of 1568 respondents have been enrolled in the non-cohort registry, including 1065 respondents with non-valvular AF (67.8%) and 503 respondents with valvular AF (32.2%). We believe that the OneAF registry will provide insight into the regional variability of anticoagulant treatment for AF, the implementation of rhythm/rate control approaches, and the clinical outcomes concerning cardiocerebrovascular events. TRIAL REGISTRATION: Registered at clinicaltrials.gov (NCT04222868). Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. |
|
adolescent; adult; aged; atrial fibrillation; clinical trial; female; human; Indonesia; male; middle aged; multicenter study; prospective study; register; very elderly; young adult; Adolescent; Adult; Aged; Aged, 80 and over; Atrial Fibrillation; Female; Humans; Indonesia; Male; Middle Aged; Prospective Studies; Registries; Young Adult |
NLM (Medline) |
15365964 |
|
34106597 |
Article |
Q4 |
204 |
19087 |
|
|
398 |
Setiabudiawan B., Sitaresmi M.N., Sapartini G., Sumadiono S., Citraresmi E., Sekartini R., Putra A.M., Jo J. |
57189310070;16040647800;57203168733;55581650500;57224512641;50162572300;57224522586;55345586200; |
Growth Patterns of Indonesian Infants with Cow's Milk Allergy and Fed with Soy-Based Infant Formula |
2021 |
Pediatric Gastroenterology, Hepatology and Nutrition |
24 |
3 |
|
316 |
324 |
|
1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107767665&doi=10.5223%2fPGHN.2021.24.3.316&partnerID=40&md5=426ce2a647c7efc4e412e462e9a020a5 |
Department of Child Health, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia; Department of Child Health, Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia; Department of Child Health, Harapan Kita Child and Mother Hospital, Jakarta, Indonesia; Department of Child Health, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Child Health, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Danone Nutricia Research, Singapore |
Setiabudiawan, B., Department of Child Health, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia; Sitaresmi, M.N., Department of Child Health, Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia; Sapartini, G., Department of Child Health, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia; Sumadiono, S., Department of Child Health, Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia; Citraresmi, E., Department of Child Health, Harapan Kita Child and Mother Hospital, Jakarta, Indonesia; Sekartini, R., Department of Child Health, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Putra, A.M., Department of Child Health, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Jo, J., Danone Nutricia Research, Singapore |
Purpose: The use of soy-based infant formula has increased widely in infants with cow's milk allergy (CMA). This study aimed to provide evidence on the growth pattern of CMA infants fed with soy-based infant formula in an Indonesian setting. Methods: A multi-site, intervention study was conducted among full-term and normal birth weight CMA infants. Within six months, the subjects were provided with a soy-based infant formula. Weight, height, and head circumference were measured at baseline, weeks 4, 8, 12, 16, 20, and 24. Adverse events were recorded by scoring atopic dermatitis and symptom-based clinical scores. Results: Based on the World Health Organization growth chart, we found that most of subjects had normal nutritional status for weight-for-age, length-for-age, weight-for-length, and head-circumference-for-age. There were statistically significant differences between baseline and end-line for weight-for-age, length-for-age, weight-for-length, and head circumference-for-age nutritional status. No allergic symptoms or intolerance toward soy formula were observed at the end of the intervention period. Conclusion: These results show that infants fed with soy-based infant formula have a normal pattern of growth. Copyright © 2021 by The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
Body height; Body weight; Milk hypersensitivity; Soy milk |
|
Korean Society of Pediartic Gastroenterology, Hepatology and Nutrition |
22348646 |
|
|
Article |
Q3 |
440 |
11229 |
|
|
399 |
Zein A.F.M.Z., Pribadi R.R., Khasanah U., Bestari M.B., Syam A.F. |
57213220528;57194732282;57003497900;36098747800;8443384400; |
Clinical gastroenterology and gastrointestinal endoscopy practices during the coronavirus disease 2019 pandemic in Indonesia: An online nationwide survey |
2021 |
Clinical Endoscopy |
54 |
3 |
|
348 |
355 |
|
1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107405434&doi=10.5946%2fce.2020.216&partnerID=40&md5=e370aa84b3897533db44d1a14f2b8918 |
Department of Internal Medicine, Faculty of Medicine, Universitas Swadaya Gunung Jati-Waled General Hospital, Jalan Taman Pemuda 2 Kompleks Stadion Bima, Kesambi, Kota Cirebon, West Java, 45132, Indonesia; Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Department of Biostatistics and Epidemiology, Faculty of Medicine, Universitas Swadaya Gunung Jati, Cirebon, Indonesia; Division of Gastroenterohepatology, Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran-Hasan Sadikin Hospital, Bandung, Indonesia |
Zein, A.F.M.Z., Department of Internal Medicine, Faculty of Medicine, Universitas Swadaya Gunung Jati-Waled General Hospital, Jalan Taman Pemuda 2 Kompleks Stadion Bima, Kesambi, Kota Cirebon, West Java, 45132, Indonesia; Pribadi, R.R., Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Khasanah, U., Department of Biostatistics and Epidemiology, Faculty of Medicine, Universitas Swadaya Gunung Jati, Cirebon, Indonesia; Bestari, M.B., Division of Gastroenterohepatology, Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran-Hasan Sadikin Hospital, Bandung, Indonesia; Syam, A.F., Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia |
Background/Aims: The coronavirus disease 2019 (COVID-19) pandemic has necessitated modifications to allow the safe practice of clinical gastroenterology and gastrointestinal endoscopy. This study aimed to investigate the characteristics of clinical gastroenterology and gastrointestinal endoscopy practices during the COVID-19 pandemic in Indonesia. Methods: This cross-sectional study enrolled physician members of the Indonesian Society for Digestive Endoscopy. We used an online self-administered questionnaire disseminated via social media. The 32-item survey determined the baseline characteristics of the participants, characteristics of clinical gastroenterology and gastrointestinal endoscopy practices, involvement of the physicians in the management of COVID-19, and overall impact of the pandemic on practice. All collected data were analyzed using descriptive statistics. Results: The 200 participants in this study had a median age of 50 (34-76) years. Modifications in clinical gastroenterology practice were frequently reported in the outpatient (95.5%) and inpatient (100%) settings. All participants reported changes in the gastrointestinal endoscopy practice patterns. Of the participants, 86.0% were working in high-risk zones, and several of them reported inadequate protective personal equipment (34.0%). The median overall impact score of the pandemic on practice was 9 (2-10). Conclusions: Physicians practicing clinical gastroenterology and gastrointestinal endoscopy in Indonesia work in high-risk settings. Modifications in clinical gastroenterology and gastrointestinal endoscopy practices are prevalent during the COVID-19 pandemic. © 2021 Korean Society of Gastrointestinal Endoscopy. |
Clinical; COVID-19; Gastroenterology; Gastrointestinal endoscopy; Practice |
adult; aged; coronavirus disease 2019; cross-sectional study; female; gastroenterology; gastrointestinal endoscopy; health survey; hospital patient; human; Indonesia; male; medical society; outpatient; pandemic; physician; professional practice; protective equipment shortage; questionnaire; Review; social media |
Korean Society of Gastrointestinal Endoscopy |
22342400 |
|
|
Review |
Q2 |
612 |
8256 |
|
|