No records
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459 |
Muchtar N.J., Helianthi D.R., Nareswari I. |
57216550449;57194729482;57194336586; |
Effectiveness of Electroacupuncture for Management of Young Patients with Overactive Bladder at 1-Year Follow-Up |
2021 |
Medical Acupuncture |
33 |
2 |
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169 |
174 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85104703311&doi=10.1089%2facu.2020.1462&partnerID=40&md5=14af8a2c96999e7428dd5cd493b4ac4d |
Department of Medical Acupuncture, Faculty of Medicine, Universitas Indonesia, Jakarta, Daerah Khusus Ibukota Jakarta, Indonesia |
Muchtar, N.J., Department of Medical Acupuncture, Faculty of Medicine, Universitas Indonesia, Jakarta, Daerah Khusus Ibukota Jakarta, Indonesia; Helianthi, D.R., Department of Medical Acupuncture, Faculty of Medicine, Universitas Indonesia, Jakarta, Daerah Khusus Ibukota Jakarta, Indonesia; Nareswari, I., Department of Medical Acupuncture, Faculty of Medicine, Universitas Indonesia, Jakarta, Daerah Khusus Ibukota Jakarta, Indonesia |
Background: Overactive bladder (OAB) is defined as urgency (a sudden compelling desire to pass urine with or without urge incontinence) usually associated with frequency and nocturia. OAB is a chronic condition that affects quality of life (QoL) significantly in patients. Acupuncture can help in the treatment of OAB for patients who cannot take certain medications. Case: A 32-year-old a female patient was diagnosed with OAB. She came to the department of medical acupuncture with a chief complaint of frequent urination for 15 years. Urinalysis test results were normal. Before acupuncture, a bladder ultrasound (US) showed a postvoid residual volume (PVR) of 53 mL, and a uroflowmetry test showed a maximum flow rate of 20.6 mL/s, with an average flow rate of 12.1 mL/s and a voided volume of 71 mL. Her OAB Symptom Score (OABSS) was 13 and the King's Health Questionnaire result was (KHQ) was 87. She was treated with electroacupuncture (EA). Results: After 12 EA sessions, 3 times per week, this patient's bladder US showed a PVR of 3 mL; a uroflowmetry test showed a maximum flow rate of 30.5 mL/s, with an average flow rate of 15.3 mL/s and a voided volume of 120 mL. Her OABSS score was 7. Her KHQ score was 0. Conclusions: OAB can be treated with EA to improve QoL, as seen by this patient's decreasing OABSS and KHQ scores, reduced PVR, and increase the voided volume. © Copyright 2021, Mary Ann Liebert, Inc., publishers 2021. |
acupuncture; bladder hyperactivity; electroacupuncture; incontinence; nocturia; Overactive bladder |
albumin; bilirubin; glucose; ketone; urobilinogen; abdominal surgery; adult; appendicitis; Article; asepsis; case report; cesarean section; clinical article; echography; electroacupuncture; female; flow rate; follow up; human; informed consent; laboratory test; micturition; overactive bladder; patient comfort; pollakisuria; postvoid residual urine volume; priority journal; social life; urinalysis; uroflowmetry; vaginal delivery; voided volume |
Mary Ann Liebert Inc. |
19336586 |
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Article |
Q2 |
281 |
15498 |
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460 |
Darmaputra D.C., Zaman F.Y., Khu Y.L., Nagalingam V., Liew D., Aung A.K. |
57223041347;57208759841;57208757691;57215386437;7003970080;55117996600; |
Cost-analysis of opportunistic influenza vaccination in general medical inpatients |
2021 |
Internal Medicine Journal |
51 |
4 |
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591 |
595 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85104572736&doi=10.1111%2fimj.15270&partnerID=40&md5=6be726bbda46f6b4342a09dd962a3b11 |
Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; Department of General Medicine, The Alfred Hospital, Melbourne, VIC, Australia |
Darmaputra, D.C., Faculty of Medicine, University of Indonesia, Jakarta, Indonesia, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; Zaman, F.Y., Department of General Medicine, The Alfred Hospital, Melbourne, VIC, Australia; Khu, Y.L., Department of General Medicine, The Alfred Hospital, Melbourne, VIC, Australia; Nagalingam, V., Department of General Medicine, The Alfred Hospital, Melbourne, VIC, Australia; Liew, D., School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia, Department of General Medicine, The Alfred Hospital, Melbourne, VIC, Australia; Aung, A.K., School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia, Department of General Medicine, The Alfred Hospital, Melbourne, VIC, Australia |
Influenza vaccination is an important preventative health measure in the elderly and those with medical comorbidities. It has been shown to reduce hospitalisations, cardiovascular and respiratory complications. A significant proportion of patients admitted to general medicine are eligible for opportunistic inpatient influenza vaccination. This study explores the cost-effectiveness of such a strategy in reducing subsequent healthcare utilisation costs. © 2021 Royal Australasian College of Physicians |
cost-analysis; elderly; influenza; inpatient; vaccination |
aged; article; cost effectiveness analysis; health care utilization; hospital patient; human; influenza vaccination; cost benefit analysis; hospital patient; hospitalization; influenza; vaccination; influenza vaccine; Aged; Cost-Benefit Analysis; Hospitalization; Humans; Influenza Vaccines; Influenza, Human; Inpatients; Vaccination |
Blackwell Publishing |
14440903 |
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33890379 |
Article |
Q3 |
596 |
8475 |
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463 |
Nurhayati F., Anggriani Y., Syahruddin E., Ramadaniati H.U., Kusumaeni T. |
57222957631;57144482600;6507688750;56380618600;57196083946; |
Cost-effectiveness analysis of tyrosine kinase inhibitors (erlotinib vs. gefitinib vs. afatinib) in non-small-cell lung cancer |
2021 |
Journal of Applied Pharmaceutical Science |
11 |
4 |
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88 |
95 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85104274393&doi=10.7324%2fJAPS.2021.110411&partnerID=40&md5=b2ac85fabd74afa9ddcab3ce12766f43 |
Pharmacy Department, Persahabatan Government Hospital, Jakarta, Indonesia; Faculty of Pharmacy, University of Pancasila, Jakarta Selatan, Indonesia; Division of Thoracic Oncology Department of Pulmonology Respiratory Medicine Faculty of Medicine, Universitas Indonesia Persahabatan National Respiratory Referral Hospital, Jakarta, Indonesia |
Nurhayati, F., Pharmacy Department, Persahabatan Government Hospital, Jakarta, Indonesia; Anggriani, Y., Faculty of Pharmacy, University of Pancasila, Jakarta Selatan, Indonesia; Syahruddin, E., Division of Thoracic Oncology Department of Pulmonology Respiratory Medicine Faculty of Medicine, Universitas Indonesia Persahabatan National Respiratory Referral Hospital, Jakarta, Indonesia; Ramadaniati, H.U., Faculty of Pharmacy, University of Pancasila, Jakarta Selatan, Indonesia; Kusumaeni, T., Pharmacy Department, Persahabatan Government Hospital, Jakarta, Indonesia |
Tyrosine kinase inhibitors (TKIs; e.g., erlotinib, gefitinib, and afatinib) are the first-line therapy for non-small-cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) (+) common mutation. The study’s objective was to analyze the cost-effectiveness of erlotinib, gefitinib, and afatinib in NSCLC patients. The subjects of the study were NSCLC patients with EGFR (+) mutation receiving either erlotinib, gefitinib, or afatinib from January 2017 to December 2019. The exclusion criteria were patients receiving the respective therapy for less than 2 months and patients unable to complete the treatment until after December 2019. The parameter of treatment effectiveness was progression-free survival (PFS), which was measured as the time from initiation of the therapy until disease progression occurred or a patient became deceased. Direct medical costs, from the hospital perspective, were calculated during the treatment. A nonparametric Kruskal-Wallis test was conducted to compare the median PFS and direct medical cost between the three treatment groups. The median PFS of patients receiving erlotinib, gefitinib, and afatinib was 8 months, 12 months, and 5 months, respectively. There were significant differences in the monthly direct medical costs between the study groups: erlotinib (IDR 13,545,116), gefitinib (IDR 14,727,887), and afatinib (IDR 12,146,834). The cost-effectiveness ratio of the study groups was as follows: erlotinib IDR 1,693,139.50/months; gefitinib IDR 1,227,323.92/months; and afatinib IDR 2,429,366.80/months. Gefitinib was the most cost-effective TKI, followed by erlotinib and afatinib. © 2021. Fitri Nurhayati et al. This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/). All rights reserved. |
afatinib; Cost-effectiveness; erlotinib; gefitinib; non-smallcell lung cancer. |
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Open Science Publishers LLP Inc. |
22313354 |
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Article |
Q2 |
286 |
15310 |
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464 |
Cahyono A.T., Louisa M., Mayang Permata T.B., Handoko, Nuryadi E., Kodrat H., Wibowo H., Hariandy Hamid A.R.A., Sekarutami S.M., Gondhowiardjo S.A. |
57222900545;41461551400;57197808751;57209984822;57197806814;57210639849;57217690943;57202054669;56576294500;6508327402; |
The potential of gallic acid as a radiosensitizer on human prostate cancer: A systematic review of preclinical studies |
2021 |
Malaysian Journal of Medicine and Health Sciences |
17 |
2 |
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246 |
254 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85104201486&partnerID=40&md5=aff7e4b57216dc4b88ee83f02823372e |
Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Integrated Laboratory, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Urology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Cahyono, A.T., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Louisa, M., Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Mayang Permata, T.B., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Handoko, Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Nuryadi, E., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Kodrat, H., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Wibowo, H., Integrated Laboratory, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Hariandy Hamid, A.R.A., Department of Urology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Sekarutami, S.M., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Gondhowiardjo, S.A., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Prostate adenocarcinoma accounts for majority of prostate cancer cases, and it was found to be highly radioresistant. Gallic acid is a phenolic acid naturally occurring in many plants, reported to exhibit biological activities in eliminating cancer cell lines and xenografts. The purpose of this study is to review gallic acid as a potential radiosensitizer agent in prostate cancer treatment. Article search was conducted in PubMed, EBSCO, and Scopus. 11 studies using different cell lines including DU145, PC-3, LNCaP, and 22Rv1 xenograft of human prostate cancer were reviewed in this paper. Gallic acid acts as a radiosensitizer mainly by increasing caspase-3 and caspase-9 activation resulting in apoptosis, while also reducing intracellular CDKs, cyclins, and cdc25 phosphatases ultimately causing G2-M cell cycle arrest. Gallic acid has a potential to be a new radiosensitizer compound in prostate cancer treatment. Additional clinical studies using gallic acid derivatives with lower hydrophilicity are needed. © 2021 UPM Press. All rights reserved. |
Apoptosis; Gallic acid; Prostate cancer; Radiobiology; Radiotherapy |
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Universiti Putra Malaysia Press |
16758544 |
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Review |
Q4 |
144 |
23823 |
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465 |
Mochtar I., Adi N.P., Hardjono A.W., Mansyur M. |
57222902121;57023786200;57222902350;37085506800; |
Return to work assessment in a radiographer assistant suffering a hemianopsia due to an ischemic stroke |
2021 |
Malaysian Journal of Medicine and Health Sciences |
17 |
2 |
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301 |
304 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85104187321&partnerID=40&md5=cad74495ef91661c388194494f7d4e58 |
Faculty of Medicine, Universitas Indonesia, Jakarta, 10320, Indonesia; Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10320, Indonesia; Occupational and Environmental Health Research Cluster, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, 10320, Indonesia; Indonesian Occupational Medicine Specialist Association, Jakarta, 10350, Indonesia |
Mochtar, I., Faculty of Medicine, Universitas Indonesia, Jakarta, 10320, Indonesia; Adi, N.P., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10320, Indonesia, Occupational and Environmental Health Research Cluster, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, 10320, Indonesia; Hardjono, A.W., Indonesian Occupational Medicine Specialist Association, Jakarta, 10350, Indonesia; Mansyur, M., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10320, Indonesia, Occupational and Environmental Health Research Cluster, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, 10320, Indonesia |
Return to work assessment (RTWA) has been performed to a radiographer assistant suffering a hemianopsia due to an ischemic stroke. Stroke occurred two months prior to the examination. The general condition of the patient was good. The systemic examination was unremarkable except the presence of a partial vision loss in the left eye and often feeling fatigue and down. Perimetry Full-field 120 Point Screening Test confirmed a left temporal hemianopsia while Patient Health Questionnaire’s score (PHQ-9) indicated a moderate depression. The two conditions were not fully compatible with the job demand of a radiographer assistant, which required a complete and clear visual field as well as a good mental status. Risk assessment indicated that the patient might encounter health and safety issues if he resumed duty without work adjustment. The clinic still wanted to employ the patient and agreed to provide support. The patient was declared ‘fit’ to resume his duty with some recommendations. © 2021 UPM Press. All rights reserved. |
Hemianopsia; Return to work; Stroke |
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Universiti Putra Malaysia Press |
16758544 |
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Article |
Q4 |
144 |
23823 |
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483 |
Sekarsari D., Amal M.Y., Napitupulu M.R., Wityaningsih Y.S. |
57193342279;57221702104;57221696697;57221685402; |
Annular pancreas mimicking hypertrophic pyloric stenosis in a female infant |
2021 |
Radiology Case Reports |
16 |
4 |
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772 |
776 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099811331&doi=10.1016%2fj.radcr.2021.01.019&partnerID=40&md5=8fd0ab9e02d41a267af411f3964c26f2 |
Department of Radiology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia |
Sekarsari, D., Department of Radiology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Amal, M.Y., Department of Radiology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Napitupulu, M.R., Department of Radiology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Wityaningsih, Y.S., Department of Radiology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia |
Annular pancreas is a rare congenital intestinal obstruction to be found in infants. It is characterized by nonbilious vomiting, abdominal distention, and feeding intolerance that share similar symptoms with other intestinal obstructions. We reported a case of 11-month-old female infant with a history of nonbilious vomiting after coughing as much as 6 times per day 1 day before admission. The patient had an incorrect provisional diagnosis of hypertrophic pyloric stenosis based on ultrasound. Later on, an upper gastrointestinal series showed dilatation of the second part of the duodenum which was successfully treated by a duodenostomy during laparotomy procedure. It is suggested that treating an intestinal obstruction needs a further investigation when the symptoms were continuously repeated. © 2021 |
Annular pancreas; Congenital abnormality; Duodenostomy; Intestinal obstruction; Upper gastrointestinal series |
hemoglobin; abdominal radiography; anemia; annular pancreas; Article; case report; chronic suppurative otitis media; clinical article; coughing; diagnostic error; diagnostic imaging; Down syndrome; duodenostomy; electrolyte disturbance; female; fever; hematocrit; human; human cell; hypertrophic pylorus stenosis; infant; intestine obstruction; laparotomy; laryngomalacia; nutritional status; obstructive airway disease; priority journal; ultrasound; vomiting |
Elsevier Inc. |
19300433 |
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Article |
Q4 |
221 |
18127 |
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484 |
Sumantri S., Rengganis I., Laksmi P.W., Hidayat R., Koesnoe S., Shatri H. |
6504606748;8449988000;8448343700;37067327300;26028015000;28767986500; |
The impact of low muscle function on health-related quality of life in Indonesian women with systemic lupus erythematosus |
2021 |
Lupus |
30 |
4 |
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680 |
686 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099752699&doi=10.1177%2f0961203320988595&partnerID=40&md5=98c96d7b7268512fcf94e7eabca204b8 |
Allergy and Clinical Immunology Division, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Depok, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Geriatric Division, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Depok, Indonesia; Rheumatology Division, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Depok, Indonesia; Psychosomatic Division, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Depok, Indonesia |
Sumantri, S., Allergy and Clinical Immunology Division, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Depok, Indonesia, Department of Internal Medicine, Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Rengganis, I., Allergy and Clinical Immunology Division, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Depok, Indonesia; Laksmi, P.W., Geriatric Division, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Depok, Indonesia; Hidayat, R., Rheumatology Division, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Depok, Indonesia; Koesnoe, S., Allergy and Clinical Immunology Division, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Depok, Indonesia; Shatri, H., Psychosomatic Division, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Depok, Indonesia |
Objective: There was no study aimed at evaluating the effect of muscle function on SLE patients' quality of life using the Sarcopenia Quality of Life (SarQoL) questionnaire. Methods: This cross-sectional study recruited 61 women with SLE consecutively, muscle function was measured with Jamar handheld-dynamometer and 6-meter walk test, HRQoL was measured with Sarcopenia Quality of Life (SarQoL) questionnaire. The cut-off point for low muscle strength (<18 kg) and low gait speed (<1.0 m/s) was according to the Asian Working Group on Sarcopenia 2019 criteria. Statistical analysis was conducted with a t-test for mean difference, and linear regression was used to adjust confounders (age, protein intake, physical exercise, and disease activity). Results: The subjects' mean muscle strength was 19.54 kg (6.94), and 44.3% (n = 27) was found to have low muscle strength. The subjects' mean gait speed was 0.77 m/s (0.20), and 90.3% (n = 55) was found to have low gait speed. The difference of total SarQoL score in subjects with normal and low muscle strength was found to be significant; 74.86 (9.48) vs. 65.49 (15.51) (p = 0.009), and still statistically significant after adjustments with age, protein intake, physical exercise level, and disease activity [B 0.56; 95% CI 0.08–1.03; p = 0.022]. The difference of total SarQoL score in subjects with normal and low physical performance was found to be not significant, 70.67 (11.08) vs. 70.72 (13.56) (p = 0.993). Conclusion: There was a significant difference in SarQoL's total score in normal compared with low muscle strength groups of Indonesian women with SLE. © The Author(s) 2021. |
health-related quality of life; Muscle function; muscle strength; physical performance; SarQoL; systemic lupus erythematosus |
corticosteroid; creatine kinase; prednisone; vitamin D; protein; adult; age; Article; corticosteroid therapy; creatine kinase blood level; cross-sectional study; disease activity; exercise; female; human; Indonesian; kidney function; low drug dose; lupus erythematosus nephritis; major clinical study; muscle function; muscle mass; muscle strength; pain severity; physical activity; physical performance; priority journal; protein intake; quality of life; quality of life assessment; Sarcopenia Quality of Life Questionnaire; six minute walk test; SLEDAI; systemic lupus erythematosus; vitamin blood level; walking speed; comparative study; epidemiology; immunology; Indonesia; muscle; pathophysiology; physiology; procedures; psychology; quality of life; questionnaire; sarcopenia; severity of illne |
SAGE Publications Ltd |
09612033 |
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33470149 |
Article |
Q2 |
1069 |
3961 |
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485 |
Simadibrata D.M., Calvin J., Wijaya A.D., Ibrahim N.A.A. |
57202134322;57221411392;57221411463;57221410260; |
Neutrophil-to-lymphocyte ratio on admission to predict the severity and mortality of COVID-19 patients: A meta-analysis |
2021 |
American Journal of Emergency Medicine |
42 |
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60 |
69 |
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22 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099401846&doi=10.1016%2fj.ajem.2021.01.006&partnerID=40&md5=9764e041c3a47b836e3ffc766efdf406 |
Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Simadibrata, D.M., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Calvin, J., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Wijaya, A.D., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Ibrahim, N.A.A., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Background: The neutrophil-to-lymphocyte ratio (NLR), an inflammatory marker, was suggested to be predictive of severity and mortality in COVID-19 patients. Here, we investigated whether NLR levels on admission could predict the severity and mortality of COVID-19 patients. Methods: A literature search was conducted on 23 July 2020 to retrieve all published articles, including grey literature and preprints, investigating the association between on-admission NLR values and severity or mortality in COVID-19 patients. A meta-analysis was performed to determine the overall standardized mean difference (SMD) in NLR values and the pooled risk ratio (RR) for severity and mortality with the 95% Confidence Interval (95%CI). Results: A total of 38 articles, including 5699 patients with severity outcomes and 6033 patients with mortality outcomes, were included. The meta-analysis showed that severe and non-survivors of COVID-19 had higher on-admission NLR levels than non-severe and survivors (SMD 0.88; 95%CI 0.72–1.04; I2 = 75.52% and 1.87; 95%CI 1.25–2.49; I2 = 97.81%, respectively). Regardless of the different NLR cut-off values, the pooled mortality RR in patients with elevated vs. normal NLR levels was 2.74 (95%CI 0.98–7.66). Conclusion: High NLR levels on admission were associated with severe COVID-19 and mortality. Further studies need to focus on determining the optimal cut-off value for NLR before clinical use. © 2021 Elsevier Inc. |
COVID-19; Meta-analysis; Mortality; Neutrophil-to-lymphocyte ratio; Severity |
Article; coronavirus disease 2019; disease association; disease severity; hospital admission; human; meta analysis; mortality; mortality risk; neutrophil lymphocyte ratio; outcome assessment; prediction; priority journal; quality control; risk assessment; sensitivity and specificity; sex ratio; survivor; systematic review; blood; diagnosis; hospitalization; lymphocyte count; neutrophil; severity of illness index; survival rate; COVID-19; Hospitalization; Humans; Lymphocyte Count; Neutrophils; Severity of Illness Index; Survival Rate |
W.B. Saunders |
07356757 |
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33453617 |
Article |
Q1 |
725 |
6828 |
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486 |
Irdam G.A., Raharja P.A.R., Sutojo B., Situmorang G.R. |
57194729795;57201013616;57218247988;57190001213; |
Predictive Model of Ureteral Obstruction of Allograft Kidney Following Living Donor Kidney Transplantation |
2021 |
Transplantation Proceedings |
53 |
3 |
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1064 |
1069 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85097068797&doi=10.1016%2fj.transproceed.2020.10.022&partnerID=40&md5=bf23ded4b9ef76b3a0dac07ece50cf93 |
Department of Urology, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Irdam, G.A., Department of Urology, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Raharja, P.A.R., Department of Urology, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Sutojo, B., Department of Urology, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Situmorang, G.R., Department of Urology, Faculty of Medicine, University of Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Background: Ureteral obstruction is one of the most frequent urologic complications of kidney transplantation. This study aimed to analyze independent factors that contribute to ureteral obstruction following kidney transplantation and develop predictive models form those factors. Methods: As many as 545 kidney transplantations were analyzed. Patients underwent transplantation between January 2014 and December 2018. Logistic regression analysis was used to develop the predictive model. Both donor and recipient demographic characteristics and operative parameters were analyzed and presented. Results: There were 37 (6.8%) subjects who developed ureteral obstruction. The independent risk factors for ureteral obstruction were multiple allograft renal arteries, older donor ages (>38 years), and older recipient age (>60 years). From the receiver operating characteristic (ROC) curve analysis, the area under the ROC curve of the predictive model was 0.843 (P < .001). Subjects with >2 renal allograft arteries, recipient age >60 years, and donor age >38 years had 83.8% probability of developing ureteral stenosis after kidney transplantation. Conclusion: Donor age, recipient age, and multiple renal arteries were independent risk factors of graft ureteral obstruction. Probability of developing ureteral obstruction should be considered pre-operatively in our population, using the proposed predictive model. © 2020 Elsevier Inc. |
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adult; allograft; Article; demography; female; graft recipient; groups by age; human; kidney donor; kidney graft; kidney transplantation; living donor; major clinical study; male; middle aged; prediction; priority journal; retrospective study; risk factor; ureter obstruction; adverse event; age; allograft; kidney; kidney artery; kidney transplantation; living donor; postoperative complication; procedures; receiver operating characteristic; statistical model; transplantation; ureter obstruction; vascularization; Adult; Age Factors; Allografts; Clinical Decision Rules; Female; Humans; Kidney; Kidney Transplantation; Living Donors; Logistic Models; Male; Middle Aged; Postoperative Complications; Renal Artery; Retrospective Studies; Risk Factors; ROC Curve; Ureteral Obstruction |
Elsevier Inc. |
00411345 |
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33248722 |
Article |
Q3 |
373 |
12773 |
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487 |
Anacak Y., Zubizarreta E., Zaghloul M., Laskar S., Alert J., Gondhowiardjo S., Giselvania A., Correa-Villar R., Pedrosa F., Dorj B., Kamer S., Howard S.C., Quintana Y., Ribeiro R.C., Rosenblatt E., Hopkins K. |
6603635579;6603081805;7005397003;26666792500;6603284454;6508327402;57217201891;57220085641;7004231496;57220089211;6508205483;7202813210;6603342439;7202534592;15767995600;7102810539; |
The Practice of Paediatric Radiation Oncology in Low- and Middle-income Countries: Outcomes of an International Atomic Energy Agency Study |
2021 |
Clinical Oncology |
33 |
4 |
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e211 |
e220 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096826569&doi=10.1016%2fj.clon.2020.11.004&partnerID=40&md5=2878f21b666e99aa706708e55c436b4a |
Ege University School of Medicine, Izmir, Turkey; International Atomic Energy AgencyVienna, Austria; National Cancer Institute, Cairo University, Cairo, Egypt; Children's Cancer Hospital, Cairo, Egypt; Tata Memorial Hospital, Mumbai, India; Instituto de Oncología y Radiobiología, Habana, Cuba; Faculty of Medicine, University of Indonesia/Dr Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Centro Infantil Boldrini, Sao Paulo, Brazil; Instituto de Medicina Integral Prof. Fernando Figueira, Recife, Brazil; National Cancer Centre, Ulaanbaatar, Mongolia; University of Tennessee Health Science Center, Memphis, TN, United States; Harvard Medical School, Boston, MA, United States; St Jude Children's Research Hospital, Memphis, TN, United States |
Anacak, Y., Ege University School of Medicine, Izmir, Turkey; Zubizarreta, E., International Atomic Energy AgencyVienna, Austria; Zaghloul, M., National Cancer Institute, Cairo University, Cairo, Egypt, Children's Cancer Hospital, Cairo, Egypt; Laskar, S., Tata Memorial Hospital, Mumbai, India; Alert, J., Instituto de Oncología y Radiobiología, Habana, Cuba; Gondhowiardjo, S., Faculty of Medicine, University of Indonesia/Dr Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Giselvania, A., Faculty of Medicine, University of Indonesia/Dr Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Correa-Villar, R., Centro Infantil Boldrini, Sao Paulo, Brazil; Pedrosa, F., Instituto de Medicina Integral Prof. Fernando Figueira, Recife, Brazil; Dorj, B., National Cancer Centre, Ulaanbaatar, Mongolia; Kamer, S., Ege University School of Medicine, Izmir, Turkey; Howard, S.C., University of Tennessee Health Science Center, Memphis, TN, United States; Quintana, Y., Harvard Medical School, Boston, MA, United States; Ribeiro, R.C., St Jude Children's Research Hospital, Memphis, TN, United States; Rosenblatt, E., International Atomic Energy AgencyVienna, Austria; Hopkins, K., International Atomic Energy AgencyVienna, Austria |
Aims: Childhood cancer survival is suboptimal in most low- and middle-income countries (LMICs). Radiotherapy plays a significant role in the standard care of many patients. To assess the current status of paediatric radiotherapy, the International Atomic Energy Agency (IAEA) undertook a global survey and a review of practice in eight leading treatment centres in middle-income countries (MICs) under Coordinated Research Project E3.30.31; ‘Paediatric radiation oncology practice in low and middle income countries: a patterns-of-care study by the International Atomic Energy Agency.’ Materials and methods: A survey of paediatric radiotherapy practices was distributed to 189 centres worldwide. Eight leading radiotherapy centres in MICs treating a significant number of children were selected and developed a database of individual patients treated in their centres comprising 46 variables related to radiotherapy technique. Results: Data were received from 134 radiotherapy centres in 42 countries. The percentage of children treated with curative intent fell sequentially from high-income countries (HICs; 82%) to low-income countries (53%). Increasing deficiencies were identified in diagnostic imaging, radiation staff numbers, radiotherapy technology and supportive care. More than 92.3% of centres in HICs practice multidisciplinary tumour board decision making, whereas only 65.5% of centres in LMICs use this process. Clinical guidelines were used in most centres. Practice in the eight specialist centres in MICs approximated more closely to that in HICs, but only 52% of patients were treated according to national/international protocols whereas institution-based protocols were used in 41%. Conclusions: Quality levels in paediatric radiotherapy differ among countries but also between centres within countries. In many LMICs, resources are scarce, coordination with paediatric oncology is poor or non-existent and access to supportive care is limited. Multidisciplinary treatment planning enhances care and development may represent an area where external partners can help. Commitment to the use of protocols is evident, but current international guidelines may lack relevance; the development of resources that reflect the capacity and needs of LMICs is required. In some LMICs, there are already leading centres experienced in paediatric radiotherapy where patient care approximates to that in HICs. These centres have the potential to drive improvements in service, training, mentorship and research in their regions and ultimately to improve the care and outcomes for paediatric cancer patients. © 2020 The Royal College of Radiologists |
Developing countries; paediatric cancer; radiation oncology; radiotherapy |
Article; cancer patient; cancer radiotherapy; cancer survival; child; childhood cancer; clinical decision making; clinical practice; clinical protocol; controlled study; diagnostic imaging; female; health care personnel; health care planning; high income country; human; low income country; major clinical study; male; middle income country; overall survival; pediatrics; practice guideline; quality of life; radiation oncology; social support; developing country; international cooperation; neoplasm; nuclear energy; oncology; Child; Developing Countries; Humans; International Agencies; Medical Oncology; Neoplasms; Nuclear Energy; Radiation Oncology |
Elsevier Ltd |
09366555 |
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33250288 |
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1037 |
4156 |
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