No records
|
591 |
Rahayatri T.H., Pramudito B.C., Soedibyo S. |
57188549965;57221381023;57216931706; |
Vaginal reconstruction using ileum segment and posterior sagittal anorectoplasty in a patient with Mayer–Rokitansky–Küster–Hauser syndrome with anorectal malformations: A case report |
2021 |
International Journal of Surgery Case Reports |
79 |
|
|
76 |
83 |
|
1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85098963856&doi=10.1016%2fj.ijscr.2020.12.085&partnerID=40&md5=c4c60b2bb5126615110a09f813253345 |
Faculty of Medicine, Universitas Indonesia, Department of Pediatric Surgery, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Faculty of Medicine, Universitas Indonesia, Department of Surgery, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Rahayatri, T.H., Faculty of Medicine, Universitas Indonesia, Department of Pediatric Surgery, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Pramudito, B.C., Faculty of Medicine, Universitas Indonesia, Department of Surgery, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Soedibyo, S., Faculty of Medicine, Universitas Indonesia, Department of Pediatric Surgery, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Vaginal agenesis with anorectal malformations is a complex pediatric condition that adversely affects various physiological processes in the body. It may cause disturbances in defecation and urination, abnormalities in the urinary and gastrointestinal tract, dysfunction of the genital and reproductive organs, and sexual function disorders. The complexity in the surgical management of vaginal agenesis includes the selection of a functional reconstruction technique for anal and vaginal formation, timing of the reconstruction, and management of complications in the associated organ system. Herein, we describe a patient with Mayer–Rokitansky–Küster–Hauser syndrome accompanied by a rectovesical fistula. Other abnormalities, such as microcephaly, polydactyly, long urethral abnormalities resembling the male urethra, and complications in the kidney and urinary tract, were observed in the patient. The associated complications included recurrent urinary tract infections, urinary overflow incontinence, vesicoureteric reflux, hydroureter, and left renal hydronephrosis. The patient underwent posterior sagittal anorectoplasty surgery and vaginal reconstruction. The long-term vaginal physiological development of patients with this condition remains unknown. © 2020 |
Anorectal malformation; MRKH syndrome; Vaginal agenesis |
adult; anorectal malformation; Article; case report; clinical article; female; human; hydronephrosis; hydroureter; ileum; intestine surgery; microcephaly; polydactyly; posterior sagittal anorectoplasty; priority journal; rectovesical fistula; recurrent disease; Rokitansky syndrome; urethra malformation; urinary tract infection; urine incontinence; vagina reconstruction; vesicoureteral reflux |
Elsevier Ltd |
22102612 |
|
|
Article |
Q3 |
232 |
17549 |
|
|
592 |
Pribadi R.R., Simadibrata M. |
57194732282;23499598400; |
Increased serum amylase and/or lipase in coronavirus disease 2019 (COVID-19) patients: Is it really pancreatic injury? |
2021 |
JGH Open |
5 |
2 |
|
190 |
192 |
|
2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85098140408&doi=10.1002%2fjgh3.12436&partnerID=40&md5=14da866c743f8e6c2bdfff73d45cc7a5 |
Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia |
Pribadi, R.R., Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Simadibrata, M., Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia |
Coronavirus disease 2019 (COVID-19) is a novel disorder caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although it mainly affects the respiratory system, the pancreas could also become the virus' target. The issue regarding pancreatic involvement in COVID-19 has been raised by several researchers. They found increased serum amylase and/or lipase in COVID-19 patients, which suggested pancreatic injury. We aimed to critically review the evidence to provide insights and to answer the very question of the possibility of pancreatic injury. Current evidence shows that increased amylase and/or lipase is not necessarily a pancreatic injury in COVID-19 patients. Those increased enzymes might also be found in other clinical conditions. © 2020 The Authors. JGH Open: An open access journal of gastroenterology and hepatology published by Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd. |
amylases; COVID-19; lipase; pancreas |
|
John Wiley and Sons Inc |
23979070 |
|
|
Review |
Q3 |
546 |
9258 |
|
|
593 |
Tedjasukmana D., Triangto K., Radi B. |
57208885305;56153395600;6603494019; |
Aerobic exercise prescription in heart failure patients with cardiac resynchronization therapy |
2021 |
Journal of Arrhythmia |
37 |
1 |
|
165 |
172 |
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85097280088&doi=10.1002%2fjoa3.12475&partnerID=40&md5=9c74c529949e818075ba5b96c9268b86 |
Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Tedjasukmana, D., Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Triangto, K., Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Radi, B., Department of Cardiology and Vascular Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Exercise for heart failure patients had been shown to be beneficial in improving functional status, and was reviewed to be safe. In cases of advanced heart failure, Cardiac Resynchronization Therapy (CRT) is a promising medical option before being a heart transplant candidate. CRT itself is a biventricular pacing device, which could detect electrical aberrance in the failing heart and provide a suitable response. Studies have shown that exercise has clear benefits toward improving an overall exercise capacity of the patients. Despite its impacts, these randomized clinical trials have varying exercise regime, and until now there has not been a standardized exercise prescription for this group of patients. The nature of CRT as a pacemaker, sometimes with defibrillator, being attached to a heart failure patient, each has its own potential exercise hazards. Therefore, providing detailed exercise prescription in adjusting to the medical condition is very essential in the field of physical medicine and rehabilitation. Being classified as a high-risk patient group, exercise challenges for the complex heart failure with CRT patients will then be discussed in this literature review, with a general aim to provide a safe, effective, and targeted exercise regime. © 2020 The Authors. Journal of Arrhythmia published by John Wiley & Sons Australia, Ltd on behalf of the Japanese Heart Rhythm Society. |
aerobic exercise prescription; cardiac resynchronization therapy; functional capacity; heart failure; rehabilitation |
aerobic exercise; atrial fibrillation; breathing exercise; cardiac resynchronization therapy; cardiopulmonary exercise test; cardiovascular magnetic resonance; congestive heart failure; coronary sinus; dyspnea; echocardiography; electrocardiography; endurance training; estimated glomerular filtration rate; exercise; exercise intensity; functional status; glycemic control; heart failure; heart function; heart left ventricle ejection fraction; heart output; heart rate; heart stroke volume; heart ventricle arrhythmia; heart ventricle fibrillation; heart ventricle tachycardia; high intensity interval training; human; hypertrophic cardiomyopathy; muscle atrophy; muscle strength; myocarditis; noninvasive ventilation; oxygen consumption; oxygen saturation; pH; physical activity; postoperative com |
Wiley-Blackwell |
18804276 |
|
|
Review |
Q3 |
463 |
10757 |
|
|
594 |
Marwali E.M., Caesa P., Rayhan M., Roebiono P.S., Fakhri D., Haas N.A., Kajimoto M., Portman M.A. |
36608535400;57204921746;57219904946;57192895321;8599513100;7103216848;56202804200;7004985824; |
The effect of oral triiodothyronine supplementation on lactate and pyruvate after paediatric cardiac surgery |
2021 |
Cardiology in the Young |
31 |
2 |
|
205 |
211 |
|
1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85095997599&doi=10.1017%2fS1047951120003698&partnerID=40&md5=ec7d88033ff87cad7cdbbc609d229529 |
Pediatric Cardiac Intensive Care Division, National Cardiovascular Center Harapan Kita, Jl. Let. Jend. S. Parman Kav. 87, Jakarta, 11420, Indonesia; Department of Cardiology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Thoracic Cardiovascular Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Pediatric Cardiology and Pediatric Intensive Care, Medical Hospital of the University of Munich, Munich, Germany; Department of Pediatrics, University of Washington School of Medicine and Division of Cardiology, Seattle Children's Hospital, Seattle, WA, United States |
Marwali, E.M., Pediatric Cardiac Intensive Care Division, National Cardiovascular Center Harapan Kita, Jl. Let. Jend. S. Parman Kav. 87, Jakarta, 11420, Indonesia; Caesa, P., Pediatric Cardiac Intensive Care Division, National Cardiovascular Center Harapan Kita, Jl. Let. Jend. S. Parman Kav. 87, Jakarta, 11420, Indonesia; Rayhan, M., Pediatric Cardiac Intensive Care Division, National Cardiovascular Center Harapan Kita, Jl. Let. Jend. S. Parman Kav. 87, Jakarta, 11420, Indonesia; Roebiono, P.S., Pediatric Cardiac Intensive Care Division, National Cardiovascular Center Harapan Kita, Jl. Let. Jend. S. Parman Kav. 87, Jakarta, 11420, Indonesia, Department of Cardiology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Fakhri, D., Department of Thoracic Cardiovascular Surgery, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Haas, N.A., Department of Pediatric Cardiology and Pediatric Intensive Care, Medical Hospital of the University of Munich, Munich, Germany; Kajimoto, M., Department of Pediatrics, University of Washington School of Medicine and Division of Cardiology, Seattle Children's Hospital, Seattle, WA, United States; Portman, M.A., Department of Pediatrics, University of Washington School of Medicine and Division of Cardiology, Seattle Children's Hospital, Seattle, WA, United States |
Abstract Objective: To determine if triiodothyronine alters lactate, glucose, and pyruvate metabolism, and if serum pyruvate concentration could serve as a predictor of low cardiac output syndrome in children after cardiopulmonary bypass procedures. Methods: This study was ancillary to the Oral Triiodothyronine for Infants and Children undergoing Cardiopulmonary bypass (OTICC) trial. Serum pyruvate was measured in the first 48 patients and lactate and glucose were measured in all 208 patients enrolled in the OTICC study on the induction of anaesthesia, 1 and 24 hours post-aortic cross-clamp removal. Patients were also defined as having low cardiac output syndrome according to the OTICC trial protocol. Result: Amongst the designated patient population for pyruvate analysis, 22 received placebo, and 26 received triiodothyronine (T3). Lactate concentrations were nearly 20 times greater than pyruvate. Lactate and pyruvate levels were not significantly different between T3 and placebo group. Glucose levels were significantly higher in the placebo group mainly at 24-hour post-cross-clamp removal. Additionally, lactate and glucose levels peaked at 1-hour post-cross-clamp removal in low cardiac output syndrome and non-low cardiac output syndrome patients, but subsequently decreased at a slower rate in low cardiac output syndrome. Lactate and pyruvate concentrations correlated with glucose only prior to surgery. Conclusion: Thyroid supplementation does not alter systemic lactate/pyruvate metabolism after cardiopulmonary bypass and reperfusion. Pyruvate levels are not useful for predicting low cardiac output syndrome. Increased blood glucose may be regarded as a response to hypermetabolic stress, seen mostly in patients with low cardiac output syndrome. © 2021 Cambridge University Press. All rights reserved. |
cardiopulmonary bypass; congenital heart disease; euthyroid sick syndrome; Keywords: Lactate; low cardiac output syndrome; pyruvate; thyroid hormone replacement |
glucose; lactic acid; liothyronine; placebo; pyruvic acid; aortic clamping; Article; cardiopulmonary bypass; child; childhood; clinical article; female; forward heart failure; glucose blood level; heart muscle reperfusion; heart surgery; human; infant; lactate blood level; male; metabolism |
Cambridge University Press |
10479511 |
|
33168128 |
Article |
Q3 |
386 |
12454 |
|
|
596 |
Dilogo I.H., Rahmatika D., Pawitan J.A., Liem I.K., Kurniawati T., Kispa T., Mujadid F. |
56161962800;57474077600;6508348067;55802927800;55213290600;56515348000;57204398571; |
Allogeneic umbilical cord-derived mesenchymal stem cells for treating critical-sized bone defects: a translational study |
2021 |
European Journal of Orthopaedic Surgery and Traumatology |
31 |
2 |
|
265 |
273 |
|
1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85089486454&doi=10.1007%2fs00590-020-02765-5&partnerID=40&md5=617ce3dfaeed87e7c027f5f3006ebb43 |
Department of Orthopaedic and Traumatology, Dr. Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine, Universitas Indonesia, CMU 2 Building 5th Floor, Jl. Diponegoro 71, Jakarta Pusat, Indonesia; Department Histology, Faculty of Medicine, Universitas Indonesia, Jl. Salemba 6, Jakarta, Indonesia; Stem Cell and Tissue Engineering Research Center, IMERI, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Anatomy, Faculty of Medicine, Universitas Indonesia, Jl. Salemba 6, Jakarta, Indonesia |
Dilogo, I.H., Department of Orthopaedic and Traumatology, Dr. Cipto Mangunkusumo General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine, Universitas Indonesia, CMU 2 Building 5th Floor, Jl. Diponegoro 71, Jakarta Pusat, Indonesia, Stem Cell and Tissue Engineering Research Center, IMERI, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Rahmatika, D., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine, Universitas Indonesia, CMU 2 Building 5th Floor, Jl. Diponegoro 71, Jakarta Pusat, Indonesia; Pawitan, J.A., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine, Universitas Indonesia, CMU 2 Building 5th Floor, Jl. Diponegoro 71, Jakarta Pusat, Indonesia, Department Histology, Faculty of Medicine, Universitas Indonesia, Jl. Salemba 6, Jakarta, Indonesia, Stem Cell and Tissue Engineering Research Center, IMERI, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Liem, I.K., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine, Universitas Indonesia, CMU 2 Building 5th Floor, Jl. Diponegoro 71, Jakarta Pusat, Indonesia, Stem Cell and Tissue Engineering Research Center, IMERI, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Anatomy, Faculty of Medicine, Universitas Indonesia, Jl. Salemba 6, Jakarta, Indonesia; Kurniawati, T., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine, Universitas Indonesia, CMU 2 Building 5th Floor, Jl. Diponegoro 71, Jakarta Pusat, Indonesia, Stem Cell and Tissue Engineering Research Center, IMERI, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Kispa, T., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine, Universitas Indonesia, CMU 2 Building 5th Floor, Jl. Diponegoro 71, Jakarta Pusat, Indonesia; Mujadid, F., Stem Cell Medical Technology Integrated Service Unit, Cipto Mangunkusumo Central Hospital, Faculty of Medicine, Universitas Indonesia, CMU 2 Building 5th Floor, Jl. Diponegoro 71, Jakarta Pusat, Indonesia |
Introduction: The current ‘gold-standard’ treatment of critical-sized bone defects (CSBDs) is autografts; however, they have drawbacks including lack of massive bone source donor site morbidity, incomplete remodeling, and the risk of infection. One potential treatment for treating CSBDs is bone marrow-derived mesenchymal stem cells (BM-MSCs). Previously, there were no studies regarding the use of human umbilical cord-mesenchymal stem cells (hUC-MSCs) for treating BDs. We aim to investigate the use of allogeneic hUC-MSCs for treating CSBDs. Method: We included subjects who were diagnosed with non-union fracture with CSBDs who agreed to undergo hUC-MSCs implantation. All patients were given allogeneic hUC-MSCs. All MSCs were obtained and cultured using the multiple-harvest explant method. Subjects were evaluated functionally using the Lower Extremity Functional Scale (LEFS) and radiologically by volume defect reduction. Result: A total of seven (3 male, 4 female) subjects were recruited for this study. The subjects age ranged from 14 to 62 years. All seven subjects had increased LEFS during the end of the follow-up period, indicating improved functional ability. The follow-up period ranged from 12 to 36 months. One subject had wound dehiscence and infection, and two subjects developed partial union. Conclusion: Umbilical cord mesenchymal stem cells are a potential new treatment for CSBDs. Additional studies with larger samples and control groups are required to further investigate the safety and efficacy of umbilical cord-derived mesenchymal stem cells for treating CSBDs. © 2020, Springer-Verlag France SAS, part of Springer Nature. |
Critical-sized bone defect; Mesenchymal stem cells; Umbilical cord |
adolescent; adult; allotransplantation; Article; bone defect; clinical article; clinical outcome; critical sized bone defect; female; follow up; fracture nonunion; functional status; human; human cell; Lower Extremity Functional Scale; male; mesenchymal stem cell transplantation; middle aged; priority journal; surgical infection; time to treatment; umbilical cord mesenchymal stem cell; wound dehiscence; young adult; autotransplantation; cell culture; cell differentiation; hematopoietic stem cell transplantation; mesenchymal stem cell; mesenchymal stem cell transplantation; umbilical cord; Adolescent; Adult; Cell Differentiation; Cells, Cultured; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Middle Aged; Transpl |
Springer-Verlag Italia s.r.l. |
16338065 |
|
32804289 |
Article |
Q1 |
851 |
5541 |
|
|
597 |
Pranata R., Yonas E., Vania R., Sidipratomo P., July J. |
57201973901;57201987097;57208328436;55674568400;24080082500; |
Efficacy and safety of PulseRider for treatment of wide-necked intracranial aneurysm—A systematic review and meta-analysis |
2021 |
Interventional Neuroradiology |
27 |
1 |
|
60 |
67 |
|
6 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85087679822&doi=10.1177%2f1591019920940521&partnerID=40&md5=03cec8e157ad6f45c39b181ca201f6fb |
Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Faculty of Medicine, Universitas YARSI, Jakarta, Indonesia; Department of Radiology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Neurosurgery, Medical Faculty, Pelita Harapan University, Tangerang, Indonesia; Neuroscience Centre Siloam Hospital, Tangerang, Indonesia |
Pranata, R., Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Yonas, E., Faculty of Medicine, Universitas YARSI, Jakarta, Indonesia; Vania, R., Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Sidipratomo, P., Department of Radiology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; July, J., Department of Neurosurgery, Medical Faculty, Pelita Harapan University, Tangerang, Indonesia, Neuroscience Centre Siloam Hospital, Tangerang, Indonesia |
Objective: PulseRider is a novel self-expanding nickel-titanium (nitinol) stent for treatment of wide-necked aneurysms, which is commonly located at the arterial branches in the brain. This systematic review and meta-analysis aims to assess the efficacy and safety of PulseRider for treatment of wide-necked intracranial aneurysm. Method: We performed a systematic literature search on articles that evaluate the efficacy and safety of PulseRider-assisted coiling of the wide-necked aneurysm from several electronic databases. The primary endpoint was adequate occlusion, defined as Raymond-Roy Class I + Raymond-Roy Class II upon immediate angiography and at six-month follow-up. Results: There were a total of 157 subjects from six studies. The rate of adequate occlusion on immediate angiography was 90% (95% CI, 85%–94%) and 91% (95% CI, 85%–96%) at six-month follow-up. Of these, Raymond-Roy Class I can be observed in 48% (95% CI, 41%–56%) of aneurysms immediately after coiling, and 64% (95% CI, 55%–72%) of aneurysms on six-month follow-up. Raymond-Roy Class II was found in 30% (95% CI, 23%–37%) of aneurysms immediately after coiling, and 25% (17–33) after six-month follow-up. Complications occur in 5% (95% CI, 1%–8%) of the patients. There were three intraoperative aneurysm rupture, three thrombus formation, three procedure-related posterior cerebral artery strokes, one vessel dissection, and one delayed device thrombosis. There was no procedure/device-related death. Conclusions: PulseRider-assisted coiling for treatment of patients with wide-necked aneurysm reached 90% adequate occlusion rate that rises up to 91% at sixth month with 5% complication rate. © The Author(s) 2020. |
Coiling; endovascular; intracranial aneurysm; PulseRider; wide-necked aneurysm |
antithrombocytic agent; adult; aneurysm rupture; angiography; arterial spin labeling; Article; blood clotting; cerebral artery disease; coil embolization; comparative effectiveness; dissection; drug safety; female; human; intracranial aneurysm; magnetic resonance angiography; male; metastasis; nuclear magnetic resonance imaging; occlusion; systematic review; thrombosis |
SAGE Publications Inc. |
15910199 |
|
32635777 |
Article |
Q2 |
574 |
8811 |
|
|
598 |
Lisnawati Y., Marianna Y., Rohsiswatmo R. |
57196459289;57267984800;55533574600; |
Increased levels of umbilical cord blood interleukin-6 (IL-6) and Serum C-Reactive Protein (CRP) in premature infants of Vitamin D deficient mothers [Peningkatan Kadar Interleukin-6 (IL-6) Darah Tali Pusat dan Serum C-Reactive Protein (CRP) pada Bayi Prematur Dari Ibu dengan Defisiensi Vitamin D] |
2021 |
Indonesian Journal of Obstetrics and Gynecology |
9 |
1 |
|
21 |
25 |
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115413252&doi=10.32771%2finajog.v9i1.1397&partnerID=40&md5=15a9474083b536a9bdea004cadbfbb69 |
Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia Persahabatan Hospital; Department of Pediatric, Faculty of Medicine, Universitas Indonesia Dr., Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Lisnawati, Y., Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia Persahabatan Hospital; Marianna, Y., Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia Persahabatan Hospital; Rohsiswatmo, R., Department of Pediatric, Faculty of Medicine, Universitas Indonesia Dr., Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Objective: Increased levels of inflammatory factors in newborns are often associated with lower maternal vitamin D levels. This study aimed to find out the relationship between maternal and umbilical cord vitamin D serum levels on umbilical cord Interleukin-6 (IL-6) and serum C-Reactive Protein (CRP) levels in premature infants. Methods: The study was an observational analytic, cross-sectional design in mothers who underwent preterm birth at 28-34 weeks' gestation due to premature rupture of membranes (PROM) and their infants at Dr. Cipto Mangunkusumo General Hospital (RSCM), Jakarta and Persahabatan General Hospital, Jakarta, from January 2017 to August 2018. Levels of serum vitamin D of the maternal and umbilical cord, umbilical cord IL-6 and serum CRP in premature infants were recorded. Vitamin D level was divided into deficiency (<10 ng/mL), insufficiency (10-29 ng/mL), and normal (≥30 ng/mL) groups. The relationship of vitamin D levels with IL-6 and CRP was carried out using Kruskal Wallis test. Results: A total of 70 subjects met the research criteria. Umbilical cord IL-6 and serum CRP levels in premature infants of vitamin D deficient mothers were higher (20.31 pg/mL and 0.50 mg/L) compared to insufficient (3.34 pg/mL and 0.45 mg/L) and normal mothers (3.29 pg/mL and 0.30 mg/L), although not statistically significant (IL-6 p = 0.665, CRP p = 0.89). Referring to the umbilical cord blood vitamin D levels, the results were different and not as expected, in which the umbilical cord IL-6 and serum CRP levels of preterm infants in the deficiency (3.76 pg/mL and 0.35 mg/L) and insufficiency (3.37 pg/mL and 0.40 mg/L) groups were lower (IL-6) and not different (CRP) than the normal group (9.41 pg/mL and 0.40 mg/L). Conclusions: There were atendency for an increase in umbbilical cord IL-6 and serum CRP level in premature infants of Vitamin D deficient mother although these were not statistically significant. Based on the levels of vitamin D umbilical cord blood, the CRP levels in the serum of premature infants were not different, while the IL-6 levels in the deficiency and insufficiency group were lower than in the normal group. © Creative Commons Atribuição-Não Comercial 4.0 Internacional |
CRP; IL-6; Maternal Vitamin D; Umbilical cord Vitamin D |
|
Indonesian Society of Obstetrics and Gynecology |
23386401 |
|
|
Article |
#N/A |
#N/A |
#N/A |
|
|
599 |
Witjaksono J., Witjaksono F., Perdana A.A. |
6508217612;57070455800;57267346600; |
Role of lifestyle modification through dietary changes to endometrial receptivity on infertility women and obesity with polycystic ovary syndrome [Peran Perubahan Gaya Hidup melalui Perubahan Pola Diet terhadap Reseptivitas Endometrium Perempuan Infertil dan Obesitas dengan Sindrom Ovarium Polikistik] |
2021 |
Indonesian Journal of Obstetrics and Gynecology |
9 |
1 |
|
49 |
54 |
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115407296&doi=10.32771%2finajog.v9i1.1415&partnerID=40&md5=e89d3e78b19a2a91949fb5c93e148d3b |
Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo General Hospital Indonesia, Jakarta, Indonesia; Department of Clinical Nutrition, Faculty of Medicine, Universitas Indonesia Dr. Cipto Mangunkusumo General Hospital Indonesia, Jakarta, Indonesia |
Witjaksono, J., Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo General Hospital Indonesia, Jakarta, Indonesia; Witjaksono, F., Department of Clinical Nutrition, Faculty of Medicine, Universitas Indonesia Dr. Cipto Mangunkusumo General Hospital Indonesia, Jakarta, Indonesia; Perdana, A.A., Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo General Hospital Indonesia, Jakarta, Indonesia |
Objective: To investigate the effect of lifestyle modification on endometrial receptivity of obese women with polycystic ovary syndrome using ultrasonography. Methods: This observational study was conducted at Dr. Cipto Mangunkusumo General Hospital Jakarta from August 2019 to May 2020. A total of 14 subjects were participated in this study. The subjects were advised to get nutrition counseling by nutritionist and then followed up the endometrial profiles for 6 months by ultrasonography. Results: A total 19 subjects were received nutrition counseling by Clinical nutritionist, but then, only 14 subjects were evaluated the endometrial study by Ultrasonography. There were several significant result between before and after treatment some subjects such as calories, body weight, body mass index, waist circumference (p<0.05) and type of the endometrial vascular zone, endometrium volume, and vascular flow index by ultrasonography (p<0.05). In this study, no significant results have been found on the correlation between dietary changes and changes in endometrial receptivity profiles. Conclusions: No significant correlation was observed between changes in anthropometrics and daily calorie intake with changes in endometrial vascular zones. © Indonesian Journal of Obstetrics and Gynecology 2021. |
Endometrial receptivity; Obese; Polycystic ovary syndrome; Ultrasonography |
|
Indonesian Society of Obstetrics and Gynecology |
23386401 |
|
|
Article |
#N/A |
#N/A |
#N/A |
|
|
600 |
Kusuma F., Matondang S.B., Nuranna L., Purwoto G., Khonsa O., Hyaswicaksono P. |
57192911548;57192085914;55301184300;14720170400;57268401500;57221907604; |
Postradiotherapy outcome on cervical cancer stage IIIB patients with and without paraaortic lymph nodes enlargement [Hasil Pascaradioterapi pada Pasien Kanker Serviks Stadium IIIB dengan dan tanpa Pembesaran Nodus Paraaorta] |
2021 |
Indonesian Journal of Obstetrics and Gynecology |
9 |
1 |
|
55 |
58 |
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85115385362&doi=10.32771%2finajog.v9i1.1438&partnerID=40&md5=4fe5c698192ed33c7d6916029327fcbf |
Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Department of Radiology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Kusuma, F., Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Matondang, S.B., Department of Radiology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Nuranna, L., Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Purwoto, G., Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Khonsa, O., Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Hyaswicaksono, P., Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Objective: To determine whether there are differences in clinical response after radiotherapy and 1 year survival in patients with advanced cervical cancer with and without enlargement of PALN. Methods: An observational analytic study using a retrospective cohort method was done using consecutive sampling. The subjects of this study were all women with a primary diagnosis of stages IIB to IVB cervical cancer who came to the gynecological oncology clinic of Dr. Cipto Mangunkusumo National General Hospital and underwent MRI examination before undergoing treatment in January 2016 to May 2017. Results: Among 76 subjects studied, there were 4 (5.1%) subjects who had enlarged PALN. There were no significant differences between the enlargement status of PALN and age (p = 0.829), age of first sexual intercourse (p = 0.33), parity (p = 0.642), mass diameter (p = 0.777). Patients with PALN enlargement have 2.13 times risk of having negative radiotherapy outcome (p = 0.02, OR 2.13, CI95% 1.12 - 4.07). There was no difference in 1-year survival between patients with and without enlargement of PALN (median 201 vs. 293, p = 0.072). Conclusions: Patients with PALN enlargement have increased risk of having negative radiotherapy outcome (p < 0.05). There were no differences in 1 year survival between patients with advanced cervical cancer with enlargement PALN. © Indonesian Journal of Obstetrics and Gynecology 2021. |
Cervical cancer; Lymph node enlargement; Paraaortic; Radiotherapy |
|
Indonesian Society of Obstetrics and Gynecology |
23386401 |
|
|
Article |
#N/A |
#N/A |
#N/A |
|
|
603 |
Clarissa A., Sutandi N., Fath A.A. |
57201653912;57201654034;57257442900; |
Stem-Cell Therapy Following High-Dose Chemotherapy in Advanced Retinoblastoma: A Systematic Review |
2021 |
Asia-Pacific journal of ophthalmology (Philadelphia, Pa.) |
10 |
4 |
|
397 |
407 |
|
|
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85114846321&doi=10.1097%2fAPO.0000000000000372&partnerID=40&md5=bd9b021766dfa6bd6c9f108c62bd4c7c |
Faculty of Medicine, Universitas IndonesiaJakarta, Indonesia |
Clarissa, A., Faculty of Medicine, Universitas IndonesiaJakarta, Indonesia; Sutandi, N.; Fath, A.A. |
PURPOSE: To analyze the risk and benefit of high-dose chemotherapy followed by stem cell transplantation (HDCT-SCT) treatment in patients with advanced retinoblastoma. DESIGN: Systematic review. METHODS: A comprehensive literature search from 4 online databases, including PubMed, Scopus, EBSCO, and Cochrane was done for original studies evaluating the use of HDCT followed by SCT in the treatment of patients with advanced retinoblastoma. The last search was performed on April 15, 2020. RESULTS: A total of 35 studies consisting of 160 patients were considered suitable for inclusion. After HDCT-SCT treatment, 108/160 (67.5%) patients were alive with no evidence of disease at the last follow-up. The incidence of secondary malignancy in our data was also relatively low, which was 16/160 (10%) patients. The side effects were mainly hematological and gastrointestinal toxicities. The prognosis for metastatic cases especially the one to the central nervous system (CNS) remains poor, as shown in our data that 22 of 44 (50%) patients died due to the evidence of disease, and 12 of 44 (27%) patients acquired CNS relapse and died. CONCLUSIONS: HDCT-SCT is a promising treatment option in patients with advanced retinoblastoma. The use of HDCT-SCT in CNS metastases needs to be carefully considered, possibly by adding thiotepa or topotecan to improve tumor control. Further randomized clinical trials are needed to draw firm conclusion regarding its safety and efficacy. Copyright © 2021 Asia-Pacific Academy of Ophthalmology. Published by Wolters Kluwer Health, Inc. on behalf of the Asia-Pacific Academy of Ophthalmology. |
|
antineoplastic agent; human; multimodality cancer therapy; retina tumor; retinoblastoma; stem cell transplantation; tumor recurrence; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Humans; Neoplasm Recurrence, Local; Retinal Neoplasms; Retinoblastoma; Stem Cell Transplantation |
NLM (Medline) |
21620989 |
|
33481395 |
Article |
#N/A |
#N/A |
#N/A |
|
|