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866 |
Lesmana C.R.A., Herjuningtyas C., Inggriani S., Pratiwi Y.E., Lesmana L.A. |
8977683000;57222165389;35329838800;57222163306;55920139300; |
Bedside Percutaneous Approach in a Critically Ill ICU Patient with Complex Pancreatobiliary Disorder Followed by Endoscopic Approach: Lessons Learnt from a Tertiary Referral Center |
2021 |
Case Reports in Gastroenterology |
15 |
1 |
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210 |
217 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101734257&doi=10.1159%2f000513282&partnerID=40&md5=b06514b9ba8afa5ed7ce24173ab5b336 |
Hepatobiliary Division, Department of Internal Medicine, Dr. Cipto Mangunkusumo National General Hospital, Medical Faculty University of Indonesia, Jakarta, Indonesia; Digestive Disease and GI Oncology Center, Medistra Hospital, Jakarta, Indonesia; Department of Anesthesiology, Medistra Hospital, Jakarta, Indonesia; Department of Radiology, Medistra Hospital, Jakarta, Indonesia |
Lesmana, C.R.A., Hepatobiliary Division, Department of Internal Medicine, Dr. Cipto Mangunkusumo National General Hospital, Medical Faculty University of Indonesia, Jakarta, Indonesia, Digestive Disease and GI Oncology Center, Medistra Hospital, Jakarta, Indonesia; Herjuningtyas, C., Department of Anesthesiology, Medistra Hospital, Jakarta, Indonesia; Inggriani, S., Department of Radiology, Medistra Hospital, Jakarta, Indonesia; Pratiwi, Y.E., Digestive Disease and GI Oncology Center, Medistra Hospital, Jakarta, Indonesia; Lesmana, L.A., Digestive Disease and GI Oncology Center, Medistra Hospital, Jakarta, Indonesia |
Pancreatobiliary disorder is a challenging clinical condition, especially when this condition is causing severe infection or biliary sepsis, and sometimes it requires intensive care unit (ICU) treatment. Biliary drainage is the mainstay of therapy; however, the choice of the drainage method is dependent on the patient's clinical condition and the disease itself. A 79-year-old female was transferred on a ventilator to our ICU from another hospital due to biliary sepsis, a large common bile duct stone, and an infected pancreatic pseudocyst. The patient also has other comorbidities such as heart problems, hypothyroidism, and diabetes mellitus. Bedside percutaneous transhepatic biliary drainage without fluoroscopy and percutaneous cyst aspiration was successfully performed, which improved the patient's condition; this was followed by an endoscopic approach, i.e., endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic ultrasound-guided pancreatic pseudocyst drainage. The clinical improvement showed itself in the change of the patient's respiratory status and ventilator mode. In conclusion, the percutaneous approach has a big role in managing critically ill patients in the ICU setting. However, expertise, training experience, and a multidisciplinary team approach are very important for successful management and patient outcome. © 2021 The Author(s). Published by S. Karger AG, Basel. |
Biliary sepsis; Common bile duct stone; Pancreatic pseudocyst; Percutaneous approach |
amikacin; antibiotic agent; bilirubin; C reactive protein; carcinoembryonic antigen; insulin; levothyroxine; piperacillin plus tazobactam; triacylglycerol lipase; aged; Article; artificial ventilation; biliary tract drainage; biliary tract endoscopy; case report; clinical article; common bile duct stone; comorbidity; continuous positive airway pressure; critically ill patient; cyst aspiration; diabetes mellitus; echography; endoscopic retrograde cholangiopancreatography; female; fluoroscopy; human; hypothyroidism; intensive care unit; jaundice; magnetic resonance cholangiopancreatography; pancreas disease; pancreas pseudocyst; sepsis |
S. Karger AG |
16620631 |
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Article |
Q3 |
247 |
16829 |
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867 |
Ibrahim F., Sahlan M., Ginting M.J., Kartika Pratami D., Hermansyah H., Wijanarko A. |
54886001500;57189182661;57212472114;57222140683;15759436800;6506885367; |
Isolation of protein from the spine venom of pterois volitans found in the indonesian ocean, using a heating process, for anticancer, antiretroviral, antibacterial, and antioxidant assays |
2021 |
International Journal of Applied Pharmaceutics |
13 |
special issue 2 |
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53 |
58 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101657433&doi=10.22159%2fijap.2021.v13s2.10&partnerID=40&md5=7efd709314f7d32aab3f98fec52eeb8d |
Virology and Cancer Pathobiology Research Centre, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, 10320, Indonesia; Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, West Java, 16424, Indonesia; Research Centre for Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, West Java, 16424, Indonesia; Faculty of Mathematics and Natural Science, Universitas Indonesia, Depok, West Java, 16424, Indonesia; Laboratory of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Pancasila University, South Jakarta, DKI Jakarta, 12640, Indonesia |
Ibrahim, F., Virology and Cancer Pathobiology Research Centre, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo General Hospital, Jakarta, 10320, Indonesia; Sahlan, M., Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, West Java, 16424, Indonesia, Research Centre for Biomedical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, West Java, 16424, Indonesia; Ginting, M.J., Faculty of Mathematics and Natural Science, Universitas Indonesia, Depok, West Java, 16424, Indonesia; Kartika Pratami, D., Laboratory of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Pancasila University, South Jakarta, DKI Jakarta, 12640, Indonesia; Hermansyah, H., Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, West Java, 16424, Indonesia; Wijanarko, A., Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, West Java, 16424, Indonesia |
Objective: This research investigates the antibacterial, anticancer, antioxidant, and antiretroviral activities of the lionfish spine poison extract. Methods: Isolation and purification of the phospholipase A2 (PLA2) protein obtained from the spine poison were conducted through the following stages, including, extraction of the venom by sonication, heating, and purification using gradual saturation levels of ammonium sulfate. Furthermore, the purity and concentration of PLA2 were analyzed using the Lowry test and Marinetti’s method, respectively, while its protein content was ascertained through SDS-PAGE. Toxicity was then evaluated employing the brine shrimp lethality test (BSLT), and its anticancer activity was assessed in human cervical carcinoma cells (HeLa cells). Finally, its antioxidant, antibacterial, and antiretroviral activities were analyzed using the DPPH method, agar diffusion test against Salmonella sp. and E. coli, and SRV-2 and RT-qPCR tests, respectively. Results: The protein demonstrated 37.79% inhibition for anticancer activity, IC50 1312 ppm for antioxidant activity, 98.81%, and 89.28% inhibition of E. coli and Salmonella sp. respectively for antibacterial activity and 98.13% inhibition for antiretroviral activity. Conclusion: It can be concluded that lionfish (Pterois volitans) has the potential to be developed as an antioxidant, anticancer, antibacterial, and antiretroviral agent. Furthermore, the pharmacological activity of its spine venom was determined by isolating PLA2 protein from its extract, using an optimum heating temperature of 70 °C and an ammonium sulfate saturation level of 80%. © 2021 The Authors. Published by Innovare Academic Sciences Pvt Ltd. T. |
Antibacterial; Anticancer; Antioxidant; Antiretroviral; Crude venom; Pterois volitans |
ammonium sulfate; antineoplastic agent; antioxidant; antiretrovirus agent; caspase 3; chloramphenicol; phospholipase A2; venom; agar diffusion; antibacterial activity; antineoplastic activity; antioxidant activity; antiviral activity; Article; bacterial growth; controlled study; cytotoxicity; DNA extraction; DPPH radical scavenging assay; enzyme activity; enzyme inhibition; enzyme linked immunosorbent assay; Escherichia coli; heating; HeLa cell line; human; human cell; hydroxyl radical scavenging assay; IC50; minimum inhibitory concentration; MTT assay; nonhuman; oxygen saturation; polyacrylamide gel electrophoresis; protein content; protein isolation; protein purification; Pterois volitans; Salmonella; shrimp; Staphylococcus aureus; temperature; ultrasound; ultraviolet visible spectroscop |
Innovare Academics Sciences Pvt. Ltd |
09757058 |
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Article |
Q3 |
238 |
17272 |
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868 |
Adhimulia K.J., Alfariq L., Kamal A.F. |
57222107905;57222109165;56648996700; |
Atypical telangiectatic osteosarcoma |
2021 |
Formosan Journal of Surgery |
54 |
1 |
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28 |
31 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101461287&doi=10.4103%2ffjs.fjs_63_20&partnerID=40&md5=455cb3287eb4bb8748ca09335f8c6946 |
Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Department of Orthopedic and Traumatology, Faculty of Medicine, Cipto Mangunkusumo General Hospital, University of Indonesia, Jakarta, Indonesia; Division of Orthopedic Oncology, Department of Orthopedic and Traumatology, Faculty of Medicine, Cipto Mangunkusumo General Hospital, University of Indonesia, Jakarta, Indonesia |
Adhimulia, K.J., Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Alfariq, L., Department of Orthopedic and Traumatology, Faculty of Medicine, Cipto Mangunkusumo General Hospital, University of Indonesia, Jakarta, Indonesia; Kamal, A.F., Division of Orthopedic Oncology, Department of Orthopedic and Traumatology, Faculty of Medicine, Cipto Mangunkusumo General Hospital, University of Indonesia, Jakarta, Indonesia |
Telangiectatic osteosarcoma (TOS) is a rare malignant bone tumor. The main clinical and radiological significance of the case presentation is TOS can be easily misdiagnosed as a benign lesion such as an aneurysmal bone cyst (ABC). In this case, we present 63-year-old male with a large mass in the left leg. Imaging modalities were obtained in this patient to define the diagnosis. In this atypical case of TOS, relatively old age presentation, slow-progressing lesion, well-demarcated lesion, and lack of periosteal reaction further accentuate the similarity between TOS and ABC or other benign lesion causing high rate misdiagnosis of TOS. The histopathological examination will finally differentiate TOS from ABC. © 2021 Wolters Kluwer Medknow Publications. All rights reserved. |
Aneurysmal bone cyst; atypical presentation; telangiectatic osteosarcoma |
bone cement; lactate dehydrogenase; adult; aneurysmal bone cyst; arthrodesis; Article; atypical telangiectatic osteosarcoma; bone radiography; case report; clinical article; clinical assessment; clinical feature; comparative study; computer assisted tomography; diagnostic accuracy; diagnostic error; diaphysis; disease exacerbation; epiphysis; erythrocyte sedimentation rate; histopathology; hospital admission; human; knee; laboratory test; male; medical history; metaphysis; middle aged; mitosis; multimodal imaging; neoadjuvant chemotherapy; nuclear magnetic resonance imaging; osteosarcoma; patient referral; periosteum; physical examination; priority journal; proximal tibia; skin edema; skin induration; soft tissue; stroma cell; telangiectasia; thorax radiography; tibialis anterior muscle; t |
Wolters Kluwer Medknow Publications |
1682606X |
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Article |
Q4 |
135 |
24781 |
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870 |
Prasetyo M., Rahardja R.R., Yanuar A., Prihartono J., Setiawan S.I. |
57192905252;57222100194;57222087272;6602605635;57195939543; |
Ultrasonography evaluation of the normal ulnar nerve in adult: Comparison of the cross-sectional area at elbow extension and flexion |
2021 |
European Journal of Radiology Open |
8 |
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100331 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101370509&doi=10.1016%2fj.ejro.2021.100331&partnerID=40&md5=f9e415e711bd67bbe8b7b71cf1b20376 |
Department of Radiology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Department of Neurology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Prasetyo, M., Department of Radiology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Rahardja, R.R., Department of Radiology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Yanuar, A., Department of Neurology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Prihartono, J., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Setiawan, S.I., Department of Radiology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia |
Background: Cross-sectional area (CSA) measurement of the ulnar nerve in the adult population by using ultrasonography (US) at elbow extension and flexion has previously been reported, but not much evidence showed a significant difference between elbow extension and flexion position. Purpose: To compare the ulnar nerve CSA between elbow extension and flexion position. Methods: A comparative cross-sectional study was conducted by involving 36 healthy adults with normally functioning ulnar nerve proven by Nerve Conduction Study (NCS) or Electroneurography. The ulnar nerve CSA was measured on each elbow by using US at the level of the medial epicondyle, 2 cm distal and 2 cm proximal from the medial epicondyle. Results: The average ulnar nerve CSA at the medial epicondyle, 2 cm distal and proximal to the medial epicondyle at elbow extension respectively were 5.95 ± 0.74 mm2, 6.27 ± 0.92 mm2, and 5.92 ± 0.73 mm2. At elbow flexion, the average ulnar nerve CSA at the positions was 5.70 ± 0.83 mm2, 5.23 ± 0.87 mm2, dan 5.73 ± 0.71 mm2 respectively. The CSA of the ulnar nerve at elbow extension was significantly larger compared to the flexion position in the three areas observed in this study (p < 0.001). Conclusion: The CSA of the ulnar nerve at elbow extension position was larger compared to the flexion position. Elbow position should be considered in measuring CSA of the ulnar nerve. © 2021 The Author(s) |
Cross-sectional area; Medial epicondyle; Ulnar nerve; Ultrasonography |
adult; article; clinical article; controlled study; cross-sectional study; echography; elbow flexion; electroneurography; female; human; human experiment; male; nerve conduction; ulnar nerve |
Elsevier Ltd |
23520477 |
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Article |
Q3 |
490 |
10260 |
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874 |
Gondhowiardjo S., Christina N., Ganapati N.P.D., Hawariy S., Radityamurti F., Jayalie V.F., Octavianus S., Putra A.P., Sekarutami S.M., Prajogi G.B., Giselvania A., Adham M., Hamid A.R.A.H., Widyastuti E., Prabowo Y., Aninditha T., Purwoto G., Aman R.A., Siregar T.P., Siswoyo A.D., Lisnawati, Handjari D.R., Atmakusuma D., Rajabto W., Mulansari N.A., Ratna N., Pitoyo C.W., Panigoro S.S., Kartini D., Yulian E.D., Andrisa R.S., Jeo W.S., Wardhani R.K., Tambunan T.F.U., Agianda F., Priyambodho |
6508327402;57217200193;57222017707;57222032883;57222015964;57195939736;57217198334;57222391312;56576294500;57221911632;57217201891;14024202100;57202054669;57222381718;56682042400;57189611205;14720170400;36848942500;57222017915;57210639278;24449072000;56160657900;23472246000;36519576100;36519326000;57222024187;26022606900;56790104300;57215490523;55983956600;57222018745;57201257973;57222033979;57222024180;57222019146;57222384319; |
Five-year cancer epidemiology at the nationa referral hospital: Hospital-based cancer registry data in Indonesia |
2021 |
JCO Global Oncology |
7 |
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190 |
203 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101027387&doi=10.1200%2fGO.20.00155&partnerID=40&md5=60ffa9d74a039cb3543813b399bd6492 |
Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Otorhinolaryngology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Urology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Hemato-Oncology, Department of Pediatrics, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Orthopedics, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Neuro-Oncology, Department of Neurology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Radiology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Hematology-Oncology Medicine, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Nutrition Science Clinic, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Respirology and Critical Illness, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Oncology Surgery, Department of Surgery, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Eye Oncology, Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Digestive Surgery Division, Department of Surgery, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Medical Rehabilitation, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Psychiatry, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Gondhowiardjo, S., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Christina, N., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Ganapati, N.P.D., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Hawariy, S., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Radityamurti, F., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Jayalie, V.F., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Octavianus, S., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Putra, A.P., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Sekarutami, S.M., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Prajogi, G.B., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Giselvania, A., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Adham, M., Department of Otorhinolaryngology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Hamid, A.R.A.H., Department of Urology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Widyastuti, E., Division of Hemato-Oncology, Department of Pediatrics, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Prabowo, Y., Department of Orthopedics, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Aninditha, T., Division of Neuro-Oncology, Department of Neurology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Purwoto, G., Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Aman, R.A., Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Siregar, T.P., Department of Radiology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Siswoyo, A.D., Department of Radiology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Lisnawati, Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Handjari, D.R., Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Atmakusuma, D., Division of Hematology-Oncology Medicine, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rajabto, W., Division of Hematology-Oncology Medicine, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Mulansari, N.A., Division of Hematology-Oncology Medicine, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Ratna, N., Department of Nutrition Science Clinic, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Pitoyo, C.W., Division of Respirology and Critical Illness, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Panigoro, S.S., Division of Oncology Surgery, Department of Surgery, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Kartini, D., Division of Oncology Surgery, Department of Surgery, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Yulian, E.D., Division of Oncology Surgery, Department of Surgery, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Andrisa, R.S., Division of Eye Oncology, Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Jeo, W.S., Digestive Surgery Division, Department of Surgery, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Wardhani, R.K., Department of Medical Rehabilitation, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Tambunan, T.F.U., Department of Medical Rehabilitation, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Agianda, F., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Priyambodho, Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
PURPOSE In 2016, there were 1,308,061 cases of cancer being treated in Indonesia, with 2.2 trillion rupiahs spent, amounting to $486,960,633 in US dollars (purchasing power parity 2016). The high burden of cancers in Indonesia requires a valid data collection to inform future cancer-related policies. The purpose of this study is to report cancer epidemiological data from 2008 to 2012 based on Hospital-Based Cancer Registry (HBCR) data from Cipto Mangunkusumo Hospital, Indonesia. METHODS This was a descriptive study with cross-sectional design. Data were collected from Cipto Mangunkusumo Hospital HBCR 2008-2012. Demographical, diagnostic, stages of cancer, and histopathological types of cancer data were extracted. RESULTS After screening, 18,216 cases were included. A total of 12,438 patients were older than 39 years of age (68.3%), with a female-to-male ratio of 9:5. Most patients have cancers at advanced stages (stages III and IV, 10.2%). The most common sites of cancer were cervix uteri (2,878 cases, 15.8%), breast (2,459 cases, 13.5%), hematopoietic and reticuloendothelial systems (1,422 cases, 7.8%), nasopharynx (1,338 cases, 7.4%), and lymph nodes (1,104 cases, 6.1%). CONCLUSION From this HBCR, cancer incidence in female was almost twice the incidence in male, largely because of the burden of cervical and breast cancers. The cervix uteri as one of the top five cancer sites based on this HBCR, 2008-2012, are still approximately consistent with Global Cancer Incidence, Mortality and Prevalence 2018, which portrayed that Indonesia has been severely afflicted by cervical cancer cases more than any other Association of Southeast Asian Nations countries. The HBCR could serve as a robust database of epidemiological data for cancer cases in Indonesia. © 2021 by American Society of Clinical Oncology |
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adrenal cancer; adult; anus cancer; Article; articular cartilage; autonomic nervous system; bile duct cancer; bladder cancer; bone cancer; brain cancer; breast cancer; bronchus cancer; cancer diagnosis; cancer epidemiology; cancer incidence; cancer localization; cancer mortality; cancer of unknown primary site; cancer registry; cancer staging; cartilage cancer; central nervous system cancer; clinical examination; colon cancer; connective tissue cancer; cranial nerve cancer; cross-sectional study; demography; descriptive research; endocrine cancer; esophagus cancer; eye cancer; female; female genital tract cancer; gallbladder cancer; gingiva tumor; heart cancer; hematologic malignancy; hepatobiliary system cancer; histopathology; human; hypopharynx cancer; Indonesia; intrahepatic bile duct; |
American Society of Clinical Oncology |
26878941 |
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33539173 |
Article |
- |
0 |
32782 |
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877 |
Negara J.D.K., Mudjianto S., Budikayanti A., Adhitya Nugraha P.P. |
57221389254;57193794731;57194713932;57221981778; |
The effect of gamma wave optimization and attention on hitting skills in softball |
2021 |
International Journal of Human Movement and Sports Sciences |
9 |
1 |
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103 |
109 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100846277&doi=10.13189%2fsaj.2021.090114&partnerID=40&md5=572b9a6bf2d4f86222486dfb5b12188a |
Department of Sport Education, Faculty of Sport Education and Health, Universitas Pendidikan Indonesia, Bandung, West Java, 40154, Indonesia; Department of Neurology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10440, Indonesia |
Negara, J.D.K., Department of Sport Education, Faculty of Sport Education and Health, Universitas Pendidikan Indonesia, Bandung, West Java, 40154, Indonesia; Mudjianto, S., Department of Sport Education, Faculty of Sport Education and Health, Universitas Pendidikan Indonesia, Bandung, West Java, 40154, Indonesia; Budikayanti, A., Department of Neurology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10440, Indonesia; Adhitya Nugraha, P.P., Department of Sport Education, Faculty of Sport Education and Health, Universitas Pendidikan Indonesia, Bandung, West Java, 40154, Indonesia |
Hitting the ball is a complicated ability in softball academicie, because in appreciation to prioritizing movement skills, cognitive appearances additionally need to be investigated, one of which is attention. Meanwhile, going to hit the ball requires excellent attention for an individual student. Exhibiting gamma waves further influence arrangements of hitting performance. The objectives of this study were first, to determine the negative functional correlation between gamma brain waves and hitting skills, then second to know the positive functional correlation between attention and hitting skills and third to determine the effect of attention on increasing hitting skills. The method used in this research is an experimental method with a one-group pretest-posttest design research design. The sampling technique in this study was using a saturated sampling technique. This investigation amounted to 20 subjects, in the calculation of the Pearson product-moment correlation test using SPSS v.23. The first results collected were p-value 0.026 with an r square value of 0.25, so there is a significant negative functional correlation between gamma brain waves and hitting skills in softball learning of 25%. The second issue obtained p-value 0.017 with an r square value of 0.28, so there is a significant positive functional correlation between attention and hitting skills in softball learning by 28%. Furthermore, thirdly, the results obtained p-value 0.0001 between pre-test and post-test, with a significant increase in skills of 70.17%, so there is a significant influence between attention and hitting skills. © 2021 by authors, all rights reserved. |
Attention; Gamma Brain Waves; Hitting Skills; Softball Games |
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Horizon Research Publishing |
23814381 |
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Article |
Q4 |
132 |
25155 |
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878 |
Sitohang I.B.S., Rheza A.M., Sirait S.P., Fitri E.M., Suseno L.S. |
56734569200;57221927642;56426927400;57221929310;57202804092; |
Acne Vulgaris Mimicking Cutaneous Lupus Erythematosus in an Adolescent: Report of a Rare Case |
2021 |
Case Reports in Dermatology |
13 |
1 |
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69 |
74 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100667271&doi=10.1159%2f000511530&partnerID=40&md5=e670f0805c017b254cadf2cd24514e56 |
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia |
Sitohang, I.B.S., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Rheza, A.M., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Sirait, S.P., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Fitri, E.M., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Suseno, L.S., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia |
Acne vulgaris is a chronic and self-limiting disorder of the pilosebaceous unit which is primarily seen in adolescents. Acne vulgaris presents as polymorphic lesions, consisting of comedones, papules, pustules, cysts, nodules, scarring, and dyspigmentation. Acneiform presentation of cutaneous lupus erythematosus (CLE) is extremely rare. The presentation of CLE is notoriously diverse and often mimics a broad range of unrelated skin disorders. We present a case by referring to American College of Rheumatology (ACR) criteria for systemic lupus erythematosus (SLE); our patient's conditions did not meet any of the clinical criteria of the Systemic Lupus International Collaborating Clinics (SLICC) for SLE. Subsequent to thorough history-taking, physical examination, and laboratory evaluations, the diagnosis of acne vulgaris was established, and a diagnosis of CLE was excluded. As acneiform presentation of CLE is rare, we here present a case which resembled both acne vulgaris and CLE. We describe our experience in establishing the diagnosis of severe acne vulgaris accompanied by scars in a 12-year-old boy with a malar rash and scars on his frontal and malar area who had initially been misdiagnosed as having CLE. This unusual case highlights the broad spectrum of adolescent acne and the importance of clinical identification of the disease so that unnecessary workups might be avoided. © 2021 |
Adolescent; Cutaneous lupus erythematosus; Severe acne vulgaris |
2 hydroxyacid; antinuclear antibody; benzoyl peroxide; clindamycin; complement component C3; glycolic acid; retinoic acid; triamcinolone acetonide; acne; acne vulgaris; adolescent; Article; brain spongiosis; case report; child; clinical article; comedo; diagnostic error; epiluminescence microscopy; erythema; follow up; histopathology; human; human tissue; hyperpigmentation; hypertrophic scar; immunofluorescence; male; papule; physical examination; pustule; rash; scar; school child; skin biopsy; skin defect; skin lupus erythematosus; systemic lupus erythematosus; urinalysis |
S. Karger AG |
16626567 |
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Article |
Q3 |
338 |
13690 |
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879 |
Sitohang I.B.S., Parrol F., Fitri E.M., Nora R.L.D. |
56734569200;57221938934;57221929310;57216253806; |
Papulopustular and Ocular Rosacea with an Alleged Coincidence of Cutaneous Lupus Erythematosus: A Case Report |
2021 |
Case Reports in Dermatology |
13 |
1 |
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62 |
68 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100608017&doi=10.1159%2f000511495&partnerID=40&md5=d9521d968dd743848325d6f5df3a4bf9 |
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Sitohang, I.B.S., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Parrol, F., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Fitri, E.M., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Nora, R.L.D., Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Rosacea is a chronic inflammatory skin disease characterized by central facial erythema with or without ocular involvement. It is often difficult to distinguish rosacea from other malar rashes, one of which is acute cutaneous lupus erythematosus (CLE), particularly when there is an increase in antinuclear antibody (ANA) level. We report the case of a 16-year old woman with facial erythematous plaque accompanied by papules and pustules, reddened eyes, and swollen eyelids since the last one year. Dermoscopic examination revealed telangiectasia, and skin scraping examination with 20% potassium hydroxide identified the presence of Demodex folliculorum. Further ocular examination also revealed blepharitis, dysfunction of Meibomian gland, cicatrix, and corneal neovascularization. The ANA titer was positive (1:320), while the anti-dsDNA was negative. The patient was treated according to standard treatment for rosacea. The patient showed a satisfactory response following 2 weeks of therapy. Signs of recurring red patches with papules, pustules, telangiectasia, and identification of D. folliculorum on skin scraping examination led to the diagnosis of papulopustular rosacea. A positive ANA test may also be present in other diseases, e.g. acute CLE. Therefore, the diagnosis of rosacea remains a challenge. Thorough observation and examination must be done in order to yield an accurate diagnosis of rosacea. © 2021 |
Case report; Cutaneous lupus erythematosus; Ocular rosacea; Papulopustular rosacea |
adapalene; antinuclear antibody; doxycycline; hydroxychloroquine; metronidazole; nitric oxide; potassium hydroxide; rheumatoid factor; abdominal pain; adolescent; anemia; arthralgia; Article; blepharitis; case report; clinical article; conjunctival hyperemia; conjunctivitis; cornea neovascularization; Demodex; Demodex folliculorum; dermatitis; dyspnea; eye examination; face erythema; female; food intake; hair loss; headache; histopathology; human; meibomian gland; oxidative stress; papule; periorbital edema; psoriasis; psoriatic arthritis; pustule; rosacea; scar; skin biopsy; skin defect; sun exposure; systemic lupus erythematosus; telangiectasia |
S. Karger AG |
16626567 |
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Article |
Q3 |
338 |
13690 |
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880 |
Putri T.P., Dewi I.A.T.K., Permata T.B.M., Nuryadi E., Kodrat H., Wibowo H., Louisa M., Gondhowiardjo S.A. |
57221919322;57221917792;57197808751;57197806814;57210639849;57217690943;41461551400;6508327402; |
A mini systematic review: Eucheuma cottonii, a red algae, as a radiosensitizer? |
2021 |
Tropical Journal of Natural Product Research |
5 |
1 |
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7 |
15 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100549316&doi=10.26538%2ftjnpr%2fv5i1.2&partnerID=40&md5=0849f73cb51c327672dca7dbaca3460f |
Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Diagnostic and Research Center, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Pharmacology and Therapeutic, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Putri, T.P., Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Dewi, I.A.T.K., Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Permata, T.B.M., Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Nuryadi, E., Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Kodrat, H., Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Wibowo, H., Diagnostic and Research Center, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Louisa, M., Department of Pharmacology and Therapeutic, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Gondhowiardjo, S.A., Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Radiosensitizers assist radiotherapy in providing greater tumor inactivation. Currently there is a search for natural radiosensitizer components which are expected to provide lesser side effects than chemical radiosensitizers. Eucheuma cottonii is a plant with antioxidant and anti-tumor effects. This review aims to search for the potential use of Eucheuma cottonii as a radiosensitizer. This is a mixed review study, where the main component is a systematic review and then followed by a narrative review. This review suggests that Eucheuma cottonii has the potential to become a radiosensitizer, by interfering with the cell cycle control mechanisms and reactivation of p53. Further research is needed to explore the synergistic effect of the combined use of radiotherapy and Eucheuma cottonii. © 2021 Putri et al. |
Anti-tumour; Eucheuma cottonii; Immunomodulator; Radiosensitizer |
antineoplastic agent; birc5 protein; carrageenan; CD4 antigen; CD8 antigen; checkpoint kinase 1; cyclin dependent kinase inhibitor; Eucheuma cottonii extract; gamma interferon; immunomodulating agent; interleukin 4; mouse double minute 2 homolog; plant extract; programmed death 1 ligand 1; protein bcl 2; protein p21; protein p53; radiosensitizing agent; survivin; unclassified drug; antiapoptotic activity; antineoplastic activity; antioxidant activity; antiproliferative activity; apoptosis; cancer cell line; cell cycle regulation; cytotoxicity; gene expression; human; IC50; in vitro study; in vivo study; Kappaphycus alvarezii; MTT assay; neoplasm; nonhuman; phagocytosis; protein expression; radiosensitization; randomized controlled trial (topic); Review; synergistic effect; systematic revie |
Faculty of Pharmacy, University of Benin |
26160684 |
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Review |
Q4 |
127 |
25832 |
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882 |
Siregar A.S., Werdhani R.A., Ascobat P., Nafrialdi N., Syam A.F., Hidayat R., Wangge G. |
57221874281;57189088848;55795863600;8521176100;8443384400;37067327300;36497482500; |
Development of a module for the prevention of nonsteroidal anti-inflammatory drugs-associated gastrointestinal adverse reactions in the elderly at a primary health center |
2021 |
International Journal of Risk and Safety in Medicine |
32 |
1 |
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61 |
73 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100509044&doi=10.3233%2fJRS-200008&partnerID=40&md5=54ae75564e4436f8e65f2444aa1a5e10 |
Doctoral Program in Medical Sciences, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Department of Pharmacology, Faculty of Medicine, State Islamic University Syarif Hidayatullah Jakarta, Jakarta, Indonesia; Department of Community Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Department of Pharmacology and Therapeutics, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Department of Internal Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; South East Asian Ministers of Education Organization - Regional Center for Food and Nutrition, Pusat Kajian Gizi Regional University of Indonesia (PKGR UI), Jakarta, Indonesia |
Siregar, A.S., Doctoral Program in Medical Sciences, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia, Department of Pharmacology, Faculty of Medicine, State Islamic University Syarif Hidayatullah Jakarta, Jakarta, Indonesia; Werdhani, R.A., Department of Community Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Ascobat, P., Department of Pharmacology and Therapeutics, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Nafrialdi, N., Department of Pharmacology and Therapeutics, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Syam, A.F., Department of Internal Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Hidayat, R., Department of Internal Medicine, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Wangge, G., South East Asian Ministers of Education Organization - Regional Center for Food and Nutrition, Pusat Kajian Gizi Regional University of Indonesia (PKGR UI), Jakarta, Indonesia |
BACKGROUND: The prevention of nonsteroidal anti-inflammatory drugs (NSAIDs) adverse reactions should start from the primary health center (PHC), as the first gatekeeper in community health services. However, there is no specific module available for health care professionals (HCPs) in Indonesia for the prevention of adverse drug reactions (ADR) at PHCs. NSAID is commonly used for the elderly treated at PHC in Indonesia, even though the ADR risk is well-known. OBJECTIVE: We aimed to develop a module to be used in PHC for preventing NSAID-associated upper gastrointestinal (GI) ADRs in elderly patients treated for musculoskeletal diseases. METHODS: The module was developed based on inputs from focus group discussions (FGD) among government health officers, PHC representatives, clinical pharmacologists, internal medicine and community medicine clinicians, pharmacovigilance experts, and professional organizations. A pilot implementation was conducted to test its feasibility and its effect on the HCPs' knowledge. RESULTS: Capacity building of HCPs, development of intra-HCP cooperation, as well as standard operating procedure (SOP) for the prescription of NSAID constituted important components of the module. A pilot study of the module in two PHCs showed that it was applicable with some recommendations for improvement in duration, number of participants, room space, presentation, and use of credit points as compliments. The HCPs' knowledge was improved after following the module. CONCLUSIONS: Our study showed that the module is feasible in PHC in Indonesia and useful in improving knowledge of HPC. © 2021 - IOS Press. All rights reserved. |
adverse drug reactions; elderly; health care professional; Indonesia; NSAIDs; primary health center |
nonsteroid antiinflammatory agent; antiinflammatory agent; drug; nonsteroid antiinflammatory agent; accreditation; aged; Article; capacity building; clinician; community medicine; continuing education; controlled study; dentist; feedback system; female; gastrointestinal symptom; geriatric patient; government; health care personnel; health center; human; Indonesia; internal medicine; major clinical study; male; medical society; midwife; musculoskeletal disease; nurse; pharmacist; pharmacologist; pharmacovigilance; physician; pilot study; prescription; primary health care; professional knowledge; program feasibility; questionnaire; teamwork; workflow; adverse drug reaction; drug surveillance program; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Drug-Related Side E |
IOS Press BV |
09246479 |
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32894252 |
Article |
Q3 |
306 |
14617 |
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