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871 |
Turana Y., Widyantoro B., Situmorang T.D., Delliana J., Roesli R.M.A., Danny S.S., Suhardjono, Sofiatin Y., Hermiawaty E., Kuncoro A.S., Barack R., Beaney T., Ster A.C., Poulter N.R., Santoso A. |
56083326000;35286148600;57202120316;57208720930;26428909500;56221848700;57205723084;56815068100;57208721982;56008103000;57202111674;55614780900;57221978746;7006154423;36905206100; |
May measurement Month 2018: An analysis of blood pressure screening results from Indonesia |
2021 |
European Heart Journal, Supplement |
22 |
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H66 |
H69 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101322980&doi=10.1093%2fEURHEARTJ%2fSUAA031&partnerID=40&md5=16a05b90991c40fdd180dd4e051eaaad |
Department of Neurology, School of Medicine and Health Science, Atma Jaya Catholic University of Indonesia, Jakarta, 14440, Indonesia; Department of Cardiology - Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia; Division of Nephrology, Department of Internal Medicine, PGI Cikini Hospital, Jakarta, 10330, Indonesia; Department of Cardiology, Directorate of Non-Communicable Disease, Ministry of Health - Republic of Indonesia, Jalan Percetakan Negara 29, Jakarta, 10560, Indonesia; Department of Internal Medicine, Faculty of Medicine, Padjadjaran University, Hasan Sadikin General Hospital, Bandung, 40161, Indonesia; Division of Nephrology and Hypertension, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto, Mangunkusumo National General Hospital, Jalan Pangeran Diponegoro No: 71, Jakarta, 10430, Indonesia; Department of Public Health, Faculty of Medicine, Padjadjaran University, Jalan Prof. Eijkman 38, Bandung, 40161, Indonesia; Department of Neurology, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia; Department of Cardiology, MMC Hospital, Jakarta, Indonesia; Imperial Clinical Trials Unit, Imperial College London, Stadium House, 68 Wood Lane, Shepherd's Bush, London, W12 7RH, United Kingdom; Department of Primary Care and Public Health, Imperial College London, St Dunstan's Road, London, W6 8RP, United Kingdom |
Turana, Y., Department of Neurology, School of Medicine and Health Science, Atma Jaya Catholic University of Indonesia, Jakarta, 14440, Indonesia; Widyantoro, B., Department of Cardiology - Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia; Situmorang, T.D., Division of Nephrology, Department of Internal Medicine, PGI Cikini Hospital, Jakarta, 10330, Indonesia; Delliana, J., Department of Cardiology, Directorate of Non-Communicable Disease, Ministry of Health - Republic of Indonesia, Jalan Percetakan Negara 29, Jakarta, 10560, Indonesia; Roesli, R.M.A., Department of Internal Medicine, Faculty of Medicine, Padjadjaran University, Hasan Sadikin General Hospital, Bandung, 40161, Indonesia; Danny, S.S., Department of Cardiology - Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia; Suhardjono, Division of Nephrology and Hypertension, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto, Mangunkusumo National General Hospital, Jalan Pangeran Diponegoro No: 71, Jakarta, 10430, Indonesia; Sofiatin, Y., Department of Public Health, Faculty of Medicine, Padjadjaran University, Jalan Prof. Eijkman 38, Bandung, 40161, Indonesia; Hermiawaty, E., Department of Neurology, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia; Kuncoro, A.S., Department of Cardiology - Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia; Barack, R., Department of Cardiology, MMC Hospital, Jakarta, Indonesia; Beaney, T., Imperial Clinical Trials Unit, Imperial College London, Stadium House, 68 Wood Lane, Shepherd's Bush, London, W12 7RH, United Kingdom, Department of Primary Care and Public Health, Imperial College London, St Dunstan's Road, London, W6 8RP, United Kingdom; Ster, A.C., Imperial Clinical Trials Unit, Imperial College London, Stadium House, 68 Wood Lane, Shepherd's Bush, London, W12 7RH, United Kingdom; Poulter, N.R., Imperial Clinical Trials Unit, Imperial College London, Stadium House, 68 Wood Lane, Shepherd's Bush, London, W12 7RH, United Kingdom; Santoso, A., Department of Cardiology - Vascular Medicine, Faculty of Medicine, Universitas Indonesia, National Cardiovascular Center, Harapan Kita Hospital, Jl. S. Parman Kav 87, Slipi, Jakarta, 11420, Indonesia |
Elevated blood pressure (BP) is a significant burden worldwide, leading to high cardiocerebro-reno-vascular morbidity and mortality. For the second year of the May Measurement Month (MMM) campaign in Indonesia in 2018, we recruited 174 sites in 31 out of 34 provinces in Indonesia and screened through convenience sampling in public areas and rural primary health centres. Hypertension was defined as systolic BP ≥140 mmHg or diastolic BP ≥90 mmHg, or both, or on the basis of receiving antihypertensive medication. Blood pressure was measured three times followed the standard global MMM protocol, multiple imputation was used to estimate the mean of the 2nd and 3rd BP readings if these were not recorded. A total of 91 222 individuals were screened, and after multiple imputations, 27 331 (30.0%) had hypertension. Of individuals not receiving antihypertensive medication, 14 367 (18.4%) were hypertensive. Among the 47.4% of hypertensive individuals on antihypertensive medication, 10 106 (78.0%) had uncontrolled BP. MMM17 and MMM18 were still the most extensive standardized screening campaigns for BP measurement in Indonesia. Compared to the previous study, the proportion with uncontrolled BP on medication was significantly higher and provided the substantial challenges in managing hypertension in the rural community. © The Author(s) 2020. |
Blood pressure; Community; Control; Hypertension; Screening |
antihypertensive agent; adult; antihypertensive therapy; Article; blood pressure measurement; controlled study; cross-sectional study; female; human; hypertension; hypertensive patient; Indonesia; major clinical study; male; primary health care; priority journal; rural population |
Oxford University Press |
1520765X |
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Article |
Q3 |
389 |
12388 |
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873 |
Rosdiana D.S., Setiabudy R., Andalusia R., Gatot D., Louisa M., Bardosono S., Instiaty I. |
56955579800;6602316235;57191278723;6508292159;41461551400;21933841000;55703138400; |
Tpmt genetic variability and its association with hematotoxicity in indonesian children with acute lymphoblastic leukemia in maintenance therapy |
2021 |
Pharmacogenomics and Personalized Medicine |
14 |
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199 |
210 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101168492&doi=10.2147%2fPGPM.S288988&partnerID=40&md5=45069dfc59e995d12723c15428e48bcd |
Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Dharmais National Cancer Hospital, Jakarta, Indonesia; Drug Registration Directorate, National Agency for Drug and Food Control, Jakarta, Indonesia; Division of Hematology-Oncology, Department of Pediatrics, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Nutrition, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia |
Rosdiana, D.S., Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Setiabudy, R., Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Andalusia, R., Dharmais National Cancer Hospital, Jakarta, Indonesia, Drug Registration Directorate, National Agency for Drug and Food Control, Jakarta, Indonesia; Gatot, D., Division of Hematology-Oncology, Department of Pediatrics, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Louisa, M., Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Bardosono, S., Department of Nutrition, Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Instiaty, I., Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Purpose: Hematotoxicity monitoring in children with acute lymphoblastic leukemia (ALL) is critical to preventing life-threatening infections and drug discontinuation. The primary drug that causes hematotoxicity in ALL children is 6-mercaptopurine (6-MP). Genetic variability of the drug-metabolizing enzymes of 6-MP, thiopurine S-methyltransferase (TPMT), is one factor that might increase the susceptibility of children to hematotoxicity. The present study aimed to determine the variability in TPMT genotypes and phenotypes and its association with the occurrence of hematotoxicity in ALL children in maintenance therapy. Patients and Methods: A cross-sectional study was conducted at Cipto Mangunkusumo and Dharmais National Cancer Hospital, Jakarta, Indonesia, from June 2017 to October 2018. We included ALL patients, 1–18 years, who were receiving at least one month of 6-MP during maintenance therapy according to the Indonesian protocol for ALL 2013. Direct sequencing was used to determine TPMT*3A, *3B, and *3C genotypes, and LCMS/MS analysis was performed to measure the plasma concentrations of 6-MP and its metabolites. Association analysis between the TPMT genotype and hematotoxicity was evaluated using the unpaired t-test or Mann–Whitney’s test. Results: The prevalence of neutropenia, anemia, and thrombocytopenia in ALL children during maintenance therapy was 51.9%, 44.3%, and 6.6%, respectively. We found a low frequency of TPMT*3C, which is 0.95%. No association was found between hematotoxicity and TPMT genotypes or age, nutritional status, serum albumin levels, risk stratification, the daily dose of 6-MP, and cotrimoxazole co-administration. However, hematotoxicity was associated with 6-methylmercaptopurine (6-MeMP) plasma concentrations and the ratio 6-MeMP/6-thioguanine (6-TGN). We also found no association between TPMT genotypes and TPMT phenotypes. Conclusion: The 6-MeMP/6-TGN ratio is associated with hematotoxicity in ALL children during maintenance therapy but is not strong enough to predict hematotoxicity. © 2021 Rosdiana et al. |
Mercaptopurine; Methylmercaptopurine; Neutropenia; Thioguanine; Thiopurine methyltransferase |
6 methylthioinosine; albumin; cotrimoxazole; dexamethasone; methotrexate; thiopurine methyltransferase; tioguanine; vincristine; acute lymphoblastic leukemia; adolescent; adult; albumin blood level; anemia; Article; blood toxicity; child; cross-sectional study; drug blood level; drug safety; female; gene sequence; genetic variability; groups by age; human; human cell; Indonesia; Indonesian; liquid chromatography-mass spectrometry; maintenance therapy; major clinical study; male; neutropenia; nutritional status; prevalence; risk factor; thrombocytopenia; TPMT gene |
Dove Medical Press Ltd |
11787066 |
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Article |
Q2 |
845 |
5609 |
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874 |
Gondhowiardjo S., Christina N., Ganapati N.P.D., Hawariy S., Radityamurti F., Jayalie V.F., Octavianus S., Putra A.P., Sekarutami S.M., Prajogi G.B., Giselvania A., Adham M., Hamid A.R.A.H., Widyastuti E., Prabowo Y., Aninditha T., Purwoto G., Aman R.A., Siregar T.P., Siswoyo A.D., Lisnawati, Handjari D.R., Atmakusuma D., Rajabto W., Mulansari N.A., Ratna N., Pitoyo C.W., Panigoro S.S., Kartini D., Yulian E.D., Andrisa R.S., Jeo W.S., Wardhani R.K., Tambunan T.F.U., Agianda F., Priyambodho |
6508327402;57217200193;57222017707;57222032883;57222015964;57195939736;57217198334;57222391312;56576294500;57221911632;57217201891;14024202100;57202054669;57222381718;56682042400;57189611205;14720170400;36848942500;57222017915;57210639278;24449072000;56160657900;23472246000;36519576100;36519326000;57222024187;26022606900;56790104300;57215490523;55983956600;57222018745;57201257973;57222033979;57222024180;57222019146;57222384319; |
Five-year cancer epidemiology at the nationa referral hospital: Hospital-based cancer registry data in Indonesia |
2021 |
JCO Global Oncology |
7 |
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190 |
203 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101027387&doi=10.1200%2fGO.20.00155&partnerID=40&md5=60ffa9d74a039cb3543813b399bd6492 |
Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Otorhinolaryngology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Urology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Hemato-Oncology, Department of Pediatrics, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Orthopedics, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Neuro-Oncology, Department of Neurology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Radiology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Hematology-Oncology Medicine, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Nutrition Science Clinic, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Respirology and Critical Illness, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Oncology Surgery, Department of Surgery, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Division of Eye Oncology, Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Digestive Surgery Division, Department of Surgery, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Medical Rehabilitation, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Psychiatry, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Gondhowiardjo, S., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Christina, N., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Ganapati, N.P.D., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Hawariy, S., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Radityamurti, F., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Jayalie, V.F., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Octavianus, S., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Putra, A.P., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Sekarutami, S.M., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Prajogi, G.B., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Giselvania, A., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Adham, M., Department of Otorhinolaryngology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Hamid, A.R.A.H., Department of Urology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Widyastuti, E., Division of Hemato-Oncology, Department of Pediatrics, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Prabowo, Y., Department of Orthopedics, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Aninditha, T., Division of Neuro-Oncology, Department of Neurology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Purwoto, G., Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Aman, R.A., Department of Neurosurgery, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Siregar, T.P., Department of Radiology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Siswoyo, A.D., Department of Radiology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Lisnawati, Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Handjari, D.R., Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Atmakusuma, D., Division of Hematology-Oncology Medicine, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rajabto, W., Division of Hematology-Oncology Medicine, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Mulansari, N.A., Division of Hematology-Oncology Medicine, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Ratna, N., Department of Nutrition Science Clinic, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Pitoyo, C.W., Division of Respirology and Critical Illness, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Panigoro, S.S., Division of Oncology Surgery, Department of Surgery, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Kartini, D., Division of Oncology Surgery, Department of Surgery, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Yulian, E.D., Division of Oncology Surgery, Department of Surgery, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Andrisa, R.S., Division of Eye Oncology, Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Jeo, W.S., Digestive Surgery Division, Department of Surgery, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Wardhani, R.K., Department of Medical Rehabilitation, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Tambunan, T.F.U., Department of Medical Rehabilitation, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Agianda, F., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Priyambodho, Department of Anesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
PURPOSE In 2016, there were 1,308,061 cases of cancer being treated in Indonesia, with 2.2 trillion rupiahs spent, amounting to $486,960,633 in US dollars (purchasing power parity 2016). The high burden of cancers in Indonesia requires a valid data collection to inform future cancer-related policies. The purpose of this study is to report cancer epidemiological data from 2008 to 2012 based on Hospital-Based Cancer Registry (HBCR) data from Cipto Mangunkusumo Hospital, Indonesia. METHODS This was a descriptive study with cross-sectional design. Data were collected from Cipto Mangunkusumo Hospital HBCR 2008-2012. Demographical, diagnostic, stages of cancer, and histopathological types of cancer data were extracted. RESULTS After screening, 18,216 cases were included. A total of 12,438 patients were older than 39 years of age (68.3%), with a female-to-male ratio of 9:5. Most patients have cancers at advanced stages (stages III and IV, 10.2%). The most common sites of cancer were cervix uteri (2,878 cases, 15.8%), breast (2,459 cases, 13.5%), hematopoietic and reticuloendothelial systems (1,422 cases, 7.8%), nasopharynx (1,338 cases, 7.4%), and lymph nodes (1,104 cases, 6.1%). CONCLUSION From this HBCR, cancer incidence in female was almost twice the incidence in male, largely because of the burden of cervical and breast cancers. The cervix uteri as one of the top five cancer sites based on this HBCR, 2008-2012, are still approximately consistent with Global Cancer Incidence, Mortality and Prevalence 2018, which portrayed that Indonesia has been severely afflicted by cervical cancer cases more than any other Association of Southeast Asian Nations countries. The HBCR could serve as a robust database of epidemiological data for cancer cases in Indonesia. © 2021 by American Society of Clinical Oncology |
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adrenal cancer; adult; anus cancer; Article; articular cartilage; autonomic nervous system; bile duct cancer; bladder cancer; bone cancer; brain cancer; breast cancer; bronchus cancer; cancer diagnosis; cancer epidemiology; cancer incidence; cancer localization; cancer mortality; cancer of unknown primary site; cancer registry; cancer staging; cartilage cancer; central nervous system cancer; clinical examination; colon cancer; connective tissue cancer; cranial nerve cancer; cross-sectional study; demography; descriptive research; endocrine cancer; esophagus cancer; eye cancer; female; female genital tract cancer; gallbladder cancer; gingiva tumor; heart cancer; hematologic malignancy; hepatobiliary system cancer; histopathology; human; hypopharynx cancer; Indonesia; intrahepatic bile duct; |
American Society of Clinical Oncology |
26878941 |
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33539173 |
Article |
- |
0 |
32782 |
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875 |
Lim M.A., Kurniawan A.A. |
57216039756;57222011563; |
Dreadful Consequences of Sarcopenia and Osteoporosis due to COVID-19 Containment |
2021 |
Geriatric Orthopaedic Surgery and Rehabilitation |
12 |
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3 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101012807&doi=10.1177%2f2151459321992746&partnerID=40&md5=a0f3b09ec242d45be8f989650cec89a9 |
Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Eminence Sports Medicine and Human Performance Center, Jakarta, Indonesia; Department of Sports Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Lim, M.A., Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia, Eminence Sports Medicine and Human Performance Center, Jakarta, Indonesia; Kurniawan, A.A., Eminence Sports Medicine and Human Performance Center, Jakarta, Indonesia, Department of Sports Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
[No abstract available] |
Fragility Fractures; Geriatric Trauma; Metabolic Bone disorders; Osteoporosis; Sarcopenia |
vitamin D; absorptiometry; anthropometry; bone density; bone fragility; coronavirus disease 2019; dietary intake; dual energy X ray absorptiometry; fracture nonunion; fracture risk assessment; fragility fracture; health care personnel; hip fracture; Letter; lifestyle modification; musculoskeletal injury; osteomyelitis; osteopenia; osteoporosis; physical activity; physical performance; quality of life; sarcopenia; vitamin supplementation |
SAGE Publications Inc. |
21514585 |
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Letter |
- |
0 |
32716 |
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884 |
Pranata R., Lim M.A., Yonas E., Huang I., Nasution S.A., Setiati S., Alwi I., Kuswardhani R.A.T. |
57201973901;57216039756;57201987097;57208576645;57189373134;14325991900;15055173800;36863900500; |
Thrombocytopenia as a prognostic marker in COVID-19 patients: Diagnostic test accuracy meta-analysis |
2021 |
Epidemiology and Infection |
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11 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100393000&doi=10.1017%2fS0950268821000236&partnerID=40&md5=d8fa1ea1b15a19b5d451c4922b96ed06 |
Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Faculty of Medicine, Universitas YARSI, Jakarta, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran, Hasan Sadikin General Hospital, Bandung, Indonesia; Division of Cardiology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Department of Internal Medicine, Faculty of Medicine, Udayana University, Sanglah Teaching Hospital, Denpasar-Bali, Indonesia |
Pranata, R., Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Lim, M.A., Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Yonas, E., Faculty of Medicine, Universitas YARSI, Jakarta, Indonesia; Huang, I., Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia, Department of Internal Medicine, Faculty of Medicine, Universitas Padjadjaran, Hasan Sadikin General Hospital, Bandung, Indonesia; Nasution, S.A., Division of Cardiology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Setiati, S., Division of Geriatrics, Department of Internal Medicine, Faculty of Medicine, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Alwi, I., Division of Cardiology, Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Kuswardhani, R.A.T., Department of Internal Medicine, Faculty of Medicine, Udayana University, Sanglah Teaching Hospital, Denpasar-Bali, Indonesia |
This systematic review and meta-analysis aimed to evaluate thrombocytopenia as a prognostic biomarker in patients with COVID-19. We performed a systematic literature search using PubMed, Embase, and EuropePMC. The main outcome was composite poor outcome, a composite of mortality, severity, need for intensive care unit care, and invasive mechanical ventilation. There were 8963 patients from 23 studies. Thrombocytopenia occurred in 18% of the patients. Male gender (p=0.037) significantly reduce the incidence. Thrombocytopenia was associated with composite poor outcome (RR 1.90 [1.43, 2.52], p<0.001; I2: 92.3%). Subgroup analysis showed that thrombocytopenia was associated with mortality (RR 2.34 [1.23, 4.45], p<0.001; I2: 96.8%) and severity (RR 1.61 [1.33, 1.96], p<0.001; I2: 62.4%). Subgroup analysis for cut-off <100 × 109/L showed RR of 1.93 [1.37, 2.72], p<0.001; I2: 83.2%). Thrombocytopenia had a sensitivity of 0.26 (0.18, 0.36), specificity of 0.89 (0.84, 0.92), positive likelihood ratio of 2.3 (1.6, 3.2), negative likelihood ratio of 0.83 (0.75, 0.93), diagnostic odds ratio of 3 (2, 4), and area under curve of 0.70 (0.66 - 0.74) for composite poor outcome. Meta-regression analysis showed that the association between thrombocytopenia and poor outcome did not vary significantly with age, male, lymphocyte, d-dimer, hypertension, diabetes, and CKD. Fagan's nomogram showed that the posterior probability of poor outcome was 50% in patients with thrombocytopenia, and 26% in those without thrombocytopenia. The Deek's funnel plot was relatively symmetrical and the quantitative asymmetry test was non-significant (p = 0.14). This study indicates that thrombocytopenia was associated with poor outcome in patients with COVID-19. © 2021 Cambridge University Press. All rights reserved. |
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aged; artificial ventilation; diagnostic test; female; human; intensive care unit; male; meta analysis; middle aged; mortality; odds ratio; pathology; prognosis; sensitivity and specificity; severity of illness index; thrombocytopenia; Aged; COVID-19; Diagnostic Tests, Routine; Female; Humans; Intensive Care Units; Male; Middle Aged; Odds Ratio; Prognosis; Respiration, Artificial; SARS-CoV-2; Sensitivity and Specificity; Severity of Illness Index; Thrombocytopenia |
Cambridge University Press |
09502688 |
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33509306 |
Article |
Q2 |
992 |
4419 |
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889 |
Irdam G.A., Sutojo B., Raharja P.A.R. |
57194729795;57218247988;57201013616; |
Risk Factors of Ureteral Stenosis in Kidney Transplant Recipients: A Retrospective Study in National Referral Hospital in Indonesia |
2021 |
Advances in Urology |
2021 |
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2410951 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100218047&doi=10.1155%2f2021%2f2410951&partnerID=40&md5=8c80f4380c17c32aba39dc8572cc7807 |
Department of Urology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia |
Irdam, G.A., Department of Urology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia; Sutojo, B., Department of Urology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia; Raharja, P.A.R., Department of Urology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia |
Ureteral stenosis is one of the most common urological complications following kidney transplantations. It is occurred in 2-10% of patients and poses a significant problem to the patients as it may lead to permanent damage to renal damage. Identification of risk factors is important to prevent the incidence of ureteral stenosis. Thus, we aim to determine the risk factors of ureteral stenosis in the Indonesian population. This is a retrospective analysis of 487 kidney transplant patients performed in Cipto Mangunkusumo Hospital between 2014 and 2018. We collected and compared donor and recipient demography data in recipients who developed ureteral stenosis and recipients who did not develop ureteral stenosis. Ureteral stenosis was defined as the presence of hydronephrosis from ultrasound and increased number of serum creatinine. The overall incidence of ureteral stenosis post-kidney transplantation in our center is 6.6% (32 from 487 patients) from January 2014 until June 2018. We found that older donor and recipient age more frequent in developing ureteral stenosis post-kidney transplantation (p < 0.001). We also found that donors with number of arteries more than 2 (p < 0.001) and prolonged warm ischemic time (p < 0.05) are more frequently to develop ureteral stenosis post-kidney transplantation. There is no association between type II diabetes mellitus and hypertension with ureteral stenosis in this study. Donor age, recipient age, donor number of arteries more than 2, and prolonged warm ischemia time are associated with ureteral stenosis after kidney transplantation. © 2021 Gampo A. Irdam et al. |
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creatinine; adolescent; adult; age; aged; allograft; Article; child; creatinine blood level; disease association; female; graft recipient; human; hydronephrosis; hypertension; Indonesia; ischemia time; kidney donor; kidney graft; kidney transplantation; major clinical study; male; medical history; neurogenic bladder; non insulin dependent diabetes mellitus; postoperative period; retrospective study; risk factor; ureter obstruction; warm ischemia time |
Hindawi Limited |
16876369 |
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Article |
Q1 |
1180 |
3392 |
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893 |
Alkaff F.F., Illavi F., Salamah S., Setiyawati W., Ramadhani R., Purwantini E., Tahapary D.L. |
57208781930;57221732812;57217109015;57221720254;57219870814;57221736394;55944492500; |
The Impact of the Indonesian Chronic Disease Management Program (PROLANIS) on Metabolic Control and Renal Function of Type 2 Diabetes Mellitus Patients in Primary Care Setting |
2021 |
Journal of Primary Care and Community Health |
12 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099918670&doi=10.1177%2f2150132720984409&partnerID=40&md5=6ba221c547d10bfc27fa5120aa56a223 |
Department of Pharmacology and Therapy, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia; Department of Internal Medicine, Dr.Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Central Jakarta, Jakarta, Indonesia; Department of Public Health and Preventive Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia; Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia; Politeknik Elektronika Negeri Surabaya, Surabaya, East Java, Indonesia; Metabolic, Cardiovascular, and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Central Jakarta, Jakarta, Indonesia |
Alkaff, F.F., Department of Pharmacology and Therapy, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia; Illavi, F., Department of Internal Medicine, Dr.Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Central Jakarta, Jakarta, Indonesia; Salamah, S., Department of Public Health and Preventive Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia; Setiyawati, W., Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia; Ramadhani, R., Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia; Purwantini, E., Politeknik Elektronika Negeri Surabaya, Surabaya, East Java, Indonesia; Tahapary, D.L., Department of Internal Medicine, Dr.Cipto Mangunkusumo General Hospital, Faculty of Medicine Universitas Indonesia, Central Jakarta, Jakarta, Indonesia, Metabolic, Cardiovascular, and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Central Jakarta, Jakarta, Indonesia |
Background: Indonesia through its government National Health Insurance System has launched a non-communicable and chronic disease management program named Indonesian Chronic Disease Management Program (PROLANIS), with Type 2 Diabetes Mellitus (T2DM) and hypertension as the main focus. However, study that evaluates the clinical impact of PROLANIS in patients with T2DM is still scarce to this date. This study aims to evaluate the metabolic control and renal function of PROLANIS participants with T2DM every six month within the first 18-months of implementation. Methods: This study was a retrospective cohort study conducted at Wates sub-district, East Java using secondary data from PROLANIS group report from April 2018 to October 2019. The study population was T2DM patients who voluntarily joined the PROLANIS group in April 2018. The six-month-evaluation included metabolic parameters [body mass index (BMI), blood pressure, hemoglobin A1C, total cholesterol, high-density lipid, low-density lipid, and triglyceride (TG)] and renal parameters [blood urea nitrogen (BUN), creatinine serum, and urinary microalbumin]. Paired t-test and wilcoxon signed-rank test was used for the analysis, and the P-value was adjusted using Bonferroni correction. A P-value <.0015 was considered statistically significant, while a P-value between.0015 and.003 was considered as marginally significant. Results: A total of 30 participants were included in the analysis. Following the PROLANIS implementation, the only parameter of metabolic control that showed significant improvement was TG serum level (P <.001). Despite the worsening status of other metabolic parameters, the changes were not statistically significant except for BMI that was marginally significant (P =.002). From renal function, only BUN serum level was significantly deteriorated (P <.001), while the others did not significantly change. Conclusion: PROLANIS implementation in our study population seems to be ineffective. Future study with more primary healthcare centers needs to be done to scrutinize the clinical impact of this program nationwide. © The Author(s) 2021. |
government program; Indonesia; primary healthcare; PROLANIS; type 2 diabetes mellitus |
glycosylated hemoglobin; disease management; human; Indonesia; non insulin dependent diabetes mellitus; primary health care; retrospective study; Diabetes Mellitus, Type 2; Disease Management; Glycated Hemoglobin A; Humans; Indonesia; Primary Health Care; Retrospective Studies |
SAGE Publications Inc. |
21501319 |
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33472499 |
Article |
Q2 |
550 |
9179 |
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895 |
Tarigan T.J.E., Dwijayanti A., Setyowati S., Louisa M. |
36057746500;55743787900;54893136300;41461551400; |
Immunogenicity and efficacy of insulin glargine biosimilar ezelin versus originator insulin glargine in patients with type 2 diabetes |
2021 |
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy |
14 |
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107 |
116 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099828801&doi=10.2147%2fDMSO.S279385&partnerID=40&md5=4adefbb901a3483328866d6334ab8e3d |
Division of Endocrinology and Metabolism, Department of Internal Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Medical Pharmacy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Division of Endocrinology, Department of Internal Medicine, Gatot Soebroto Presidential Hospital, Jakarta, Indonesia; Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Tarigan, T.J.E., Division of Endocrinology and Metabolism, Department of Internal Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Dwijayanti, A., Department of Medical Pharmacy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Setyowati, S., Division of Endocrinology, Department of Internal Medicine, Gatot Soebroto Presidential Hospital, Jakarta, Indonesia; Louisa, M., Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Purpose: To compare the immunogenicity and efficacy of insulin glargine biosimilar Ezelin (EZL) versus originator insulin glargine Lantus (LAN) as a reference basal insulin in patients with type 2 diabetes (T2D). Patients and Methods: This was a randomized, multicenter, open-label, 24-week study in insulin-naïve patients with T2D, with HbA1c of >7.0%. We randomly assigned 133 eligible patients to receive either EZL or LAN. Baseline characteristics, including insulin autoantibody (IAA), zinc transporter 8 (ZnT8) antibody, HbA1C, fasting plasma glucose (FPG), 2-hour postprandial plasma glucose (2hPPG), AST, ALT, BUN, eGFR, and oral antidiabetic drugs, were obtained before starting insulin treatment. After starting treatment, insulin dose was titrated to achieve FPG target along with oral antidiabetic drugs. Patients were given home glucometer and assisted to record plasma glucose measurement and adverse event (AE). Every month, patients came to the diabetes clinic and performed a regular physical examination and intensifying treatment if needed. Out of the 133 randomized patients, only 122 completed the study and can be examined for their IAA and ZnT8 after 6 months of treatment. The study was registered in clinicaltrials.gov, NCT03352674. Results: There is a similar proportion of patients with changes of IAA from baseline: 1 out of 58 (1.7%) patients receiving EZL versus 1 out of 64 (1.6%) patients receiving LAN (p = 1.000). One patient in the EZL group (1.7%) versus none in the LAN group experienced a change of ZnT8 antibody from baseline. Similar glucose control in EZL versus LAN was determined by the change in HbA1c, FPG, and 2hPPG (−2.0%, −67.46 mg/dL, and −76.51 mg/dL in the EZL group versus −1.7%, −58.11 mg/dL, and −70.03 mg/dL in the LAN group). There were six events of documented hypoglycemia in the EZL group versus five events in the LAN group. No patients experienced diabetic ketoacidosis during the study. Conclusion: Overall, insulin glargine biosimilar EZL and originator insulin glargine LAN have shown a similar immunogenicity profile, as well as efficacy in providing glucose control and safety findings in T2D populations. © 2021 Tarigan et al. |
Biosimilar; Hyperglycemia; Insulin autoantibody; Zinc transporter 8 antibody |
acarbose; alanine aminotransferase; aspartate aminotransferase; ezelin; glucose; hemoglobin A1c; insulin antibody; insulin glargine; metformin; pioglitazone; protein antibody; sulfonylurea; unclassified drug; urea; zinc transporter 8; zinc transporter 8 antibody; acute gastroenteritis; acute kidney failure; adult; alanine aminotransferase blood level; Article; aspartate aminotransferase blood level; Bell palsy; cardiovascular disease; cerebrovascular accident; cervical spine fracture; controlled study; coughing; dermatitis; diabetic ketoacidosis; diabetic patient; diabetic ulcer; diarrhea; drug dose titration; drug efficacy; drug safety; dyspepsia; dyspnea; estimated glomerular filtration rate; fasting; female; gangrene; gastritis; gastroesophageal reflux; gastrointestinal symptom; glucose |
Dove Medical Press Ltd |
11787007 |
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Article |
Q2 |
853 |
5525 |
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896 |
Suraya A., Nowak D., Sulistomo A.W., Icksan A.G., Berger U., Syahruddin E., Bose-O’reilly S. |
57214135787;7201764407;57024018500;57194332884;7101876991;6507688750;55933417800; |
Excess risk of lung cancer among agriculture and construction workers in Indonesia |
2021 |
Annals of Global Health |
87 |
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1 |
14 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099767907&doi=10.5334%2faogh.3155&partnerID=40&md5=01b5a6cafe172bcea089864226c539b6 |
CIHLMU Center for International Health, University Hospital, LMU, Munich, Germany; Universitas Binawan, Jakarta, Indonesia; Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, LMU University Hospital, Munich, Germany; Comprehensive Pneumology Center Munich (CPC-M), Member, German Center for Lung Research (DZL), Germany; Department of Radiology, Persahabatan Hospital, National Respiratory Referral Hospital, Jakarta, Indonesia; Faculty of Medicine UPN Veteran, Jakarta, Indonesia; IBE – Institute for Medical Information Processing, Biometry and Epidemiology, LMU, Munich, Germany; Division of Thoracic Oncology Department of Pulmonology Faculty of Medicine, Universitas Indonesia Persahabatan hospital, Jakarta, Indonesia; Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, LMU University Hospital, Munich, Germany; Institute of Public Health, Medical Decision Making and Health Technology Assessment, Department of Public Health, Health Services Research and Health Technology Assessment, UMIT–Private University for Health Sciences, Medical Informatics and Technology, Austria |
Suraya, A., CIHLMU Center for International Health, University Hospital, LMU, Munich, Germany, Universitas Binawan, Jakarta, Indonesia; Nowak, D., Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, LMU University Hospital, Munich, Germany, Comprehensive Pneumology Center Munich (CPC-M), Member, German Center for Lung Research (DZL), Germany; Sulistomo, A.W., Universitas Binawan, Jakarta, Indonesia; Icksan, A.G., Department of Radiology, Persahabatan Hospital, National Respiratory Referral Hospital, Jakarta, Indonesia, Faculty of Medicine UPN Veteran, Jakarta, Indonesia; Berger, U., IBE – Institute for Medical Information Processing, Biometry and Epidemiology, LMU, Munich, Germany; Syahruddin, E., Division of Thoracic Oncology Department of Pulmonology Faculty of Medicine, Universitas Indonesia Persahabatan hospital, Jakarta, Indonesia; Bose-O’reilly, S., Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, LMU University Hospital, Munich, Germany, Institute of Public Health, Medical Decision Making and Health Technology Assessment, Department of Public Health, Health Services Research and Health Technology Assessment, UMIT–Private University for Health Sciences, Medical Informatics and Technology, Austria |
Background: In Indonesia, many occupations and industries involve a variety of hazardous and toxic materials. The ILO estimates that about 21.1% of the tracheal, bronchial, and lung cancer deaths among men were attributable to workplace hazardous substances. This study investigated the relationship between occupations or workplace exposure and the risk of lung cancer in the country. The results will help determine how Indonesia can best mitigate the risk for its workers. Objectives: This case-control study utilizes the Indonesian Standard of Industrial Classification (IndSIC) 2015 with the aim of exploring the risk of lung cancer among Indonesian workers. Methods: The study included patients aged 35 years old or older receiving thoracic CT at the radiology department of Persahabatan Hospital. The cases were histologicalconfirmed primary lung cancers, while the controls were negative thoracic CT scan for lung cancer. The subjects’ job titles and industries were classified according to IndSIC 2015 and blind to the patient’s grouping as a case or control. Logistic regression was used to determine the odds ratios for lung cancer among all sections and some divisions or groups of IndSIC 2015. Findings: The mean age was 58.1 (±10.23) years for lung cancer patients and 54.5 (±10.23) years for controls. The majority of subjects (19.6%) worked in Section G (Wholesale and retail trade; repair of motor vehicles and motorcycle). After adjusting for age, gender, level of education, and smoking habit, the risk of lung cancer was nearly three-times higher (OR = 2.8, 95% CI = 1.11–7.02) in workers of Division A01 (crop, animal production, and hunting) and two-times higher (OR = 1.9, 95% CI = 1.05–3.46) in workers of Section F (construction) compared to the workers in other sections or divisions. Conclusions: The excess risk of lung cancer among certain categories of workers confirms the need for improved policy, monitoring, and control of occupational exposure for primary cancer prevention and workers’ compensation purposes. © 2021 The Author(s). |
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adult; aged; agricultural worker; Article; cancer prevention; cancer risk; case control study; construction worker; controlled study; educational status; female; human; human tissue; Indonesia; lung cancer; major clinical study; male; medical information; motor vehicle; motorcycle; occupational exposure; occupational health; smoking habit; x-ray computed tomography; adverse event; agriculture; building industry; lung tumor; middle aged; occupation; occupational disease; occupational exposure; risk factor; very elderly; Adult; Aged; Aged, 80 and over; Agriculture; Case-Control Studies; Construction Industry; Female; Humans; Indonesia; Lung Neoplasms; Male; Middle Aged; Occupational Diseases; Occupational Exposure; Occupations; Risk Factors |
Ubiquity Press |
22149996 |
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33505867 |
Article |
Q2 |
602 |
8385 |
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899 |
Tanto I.V., Dharma S., Juzar D.A., Bono A.A.H. |
57221612652;55101301700;55358712500;57208146721; |
Ventricular Septal Rupture Complicating an Acute ST-Segment Elevation Myocardial Infarction during the COVID-19 Pandemic |
2021 |
International Journal of Angiology |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099596441&doi=10.1055%2fs-0040-1720971&partnerID=40&md5=aab866db219c647750534315d55f3fdf |
Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, Indonesian Cardiovascular Research Center, National Cardiovascular Center Harapan Kita, Jl S Parman Kav 87, Slipi, Jakarta Barat, Jakarta, 11420, Indonesia; Division of Cardiothoracic and Vascular Surgery, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia |
Tanto, I.V., Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, Indonesian Cardiovascular Research Center, National Cardiovascular Center Harapan Kita, Jl S Parman Kav 87, Slipi, Jakarta Barat, Jakarta, 11420, Indonesia; Dharma, S., Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, Indonesian Cardiovascular Research Center, National Cardiovascular Center Harapan Kita, Jl S Parman Kav 87, Slipi, Jakarta Barat, Jakarta, 11420, Indonesia; Juzar, D.A., Department of Cardiology and Vascular Medicine, Faculty of Medicine, University of Indonesia, Indonesian Cardiovascular Research Center, National Cardiovascular Center Harapan Kita, Jl S Parman Kav 87, Slipi, Jakarta Barat, Jakarta, 11420, Indonesia; Bono, A.A.H., Division of Cardiothoracic and Vascular Surgery, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia |
Ventricular septal rupture (VSR) is rare but a lethal complication of acute myocardial infarction (MI). Definite treatment requires the surgical closure of the VSR and coronary artery bypass grafting (CABG). However, the optimal timing for surgery is still controversial, particularly during the novel coronavirus disease 2019 (COVID-19) pandemic where medical procedures should be performed within the safest environment. Before surgery, a proper management in the intensive cardiovascular care unit is essential to maintain the stability of the hemodynamic profile related with VSR and determines the prognosis of the patient. We described a case of VSR complicating an anterior wall MI in a patient who admitted to our hospital during the COVID-19 pandemic that was treated successfully by surgical closure of the VSR and CABG. © 2021 BMJ Publishing Group. All rights reserved. |
bypass grafting; myocardial infarction; surgical repair; ventricular septal rupture |
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Thieme Medical Publishers, Inc. |
10611711 |
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Article |
Q3 |
293 |
15070 |
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