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284 |
Rustamadji P., Takbir M., Wuyung P.E., Kusmardi K., Wiyarta E. |
55321572200;57318063000;57192889605;56966625300;57221521342; |
Correlation between CD 34 and CD 68 expression in placental malaria with maternal anemia |
2021 |
Tropical Parasitology |
11 |
2 |
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92 |
96 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85118308075&doi=10.4103%2ftp.TP_108_20&partnerID=40&md5=a57c3187c0926ddc2e00415c87f7f7bb |
Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Anatomical Pathology, Labuha Hospital, North Maluku, South Halmahera, Indonesia |
Rustamadji, P., Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Takbir, M., Department of Anatomical Pathology, Labuha Hospital, North Maluku, South Halmahera, Indonesia; Wuyung, P.E., Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Kusmardi, K., Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Wiyarta, E., Department of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Background: Malaria is the second most life-threatening infectious disease in Indonesia, causing approximately 1-3 million deaths annually. Histopathologic studies assessing CD 68 and CD 34 protein expression in placental malaria and its association with maternal anemia are essential to determine the prognosis of malaria in pregnancy. Materials and Methods: This cross-sectional study was carried out in 2017. Thirty biopsy samples of human placental tissue were obtained from Timika and Sumba, and ten normal biopsy samples were taken from the Pathological Anatomy Department of Cipto Mangunkusumo General Hospital as comparisons. CD 34 and CD 68 protein expressions were determined using immunohistochemistry, and the resulting data were analyzed using SPSS. Results: Average hemoglobin (Hb) level was 9.5 mg/dL, 11.5 mg/dL, and 9.9 mg/dL in acute infection, chronic infection, and latent infection, respectively. A positive correlation was found between CD 68 protein expression and maternal Hb level. No correlation was found between CD34 expression and maternal anemia. Conclusions: CD 68 expression in placental tissue biopsy from Timika and Sumba residents with placental malaria was shown to be positively correlated with maternal anemia. Immunohistochemical examination of CD 68 may play a role in the early diagnosis of malaria. © 2021 Tropical Parasitology | Published by Wolters Kluwer - Medknow. |
CD 34; CD 68; Maternal anemia; Placental malaria |
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Wolters Kluwer Medknow Publications |
22295070 |
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Article |
Q3 |
418 |
11707 |
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303 |
Samara T., Wibowo H., Liem I., Prijanti A., Andrijono A. |
57208256339;57217690943;55802927800;57190863386;57208264133; |
Cullin 1 as a proangiogenic factor and its relationship with vascular endothelial growth factor and p21 are associated with the length of gestational age of pre-eclampsia |
2021 |
Journal of Natural Science, Biology and Medicine |
12 |
2 |
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140 |
144 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111296351&doi=10.4103%2fjnsbm.JNSBM-123-20&partnerID=40&md5=10efc582ba2ed72d7813100c2ebbc2d5 |
Department of Biomedical Science, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Anatomy, Faculty of Medicine, Trisakti University, Jakarta, Indonesia; Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Anatomy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Samara, T., Department of Biomedical Science, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Anatomy, Faculty of Medicine, Trisakti University, Jakarta, Indonesia; Wibowo, H., Department of Biomedical Science, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Liem, I., Department of Biomedical Science, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Anatomy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Prijanti, A., Department of Biomedical Science, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Andrijono, A., Department of Biomedical Science, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, Department of Obstetrics and Gynaecology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Background: Cullin 1 (CUL1), vascular endothelial growth factor (VEGF), and p21 are proteins that play a role in pregnancy. CUL1 and VEGF are proangiogenic factors, whereas p21 is an antiangiogenic factor. An imbalance between proangiogenic and antiangiogenic factors is one of the various factors that cause pre-eclampsia (PE). The aim of this study was to analyze CUL1 levels in the relationship with VEGF levels and p21 levels based on gestational age at delivery in PE. Materials and Methods: This was a cross-sectional study of 70 placentas from PE patients divided in two groups of gestational age at delivery: <34 weeks and ≥34 weeks. Levels of CUL1, VEGF, and p21 were examined by the enzyme-linked immunosorbent assay technique. Statistical analysis was assessed by Spearman correlation test and Chi-square test, with a significant P < 0.05. Results: Low levels of CUL1 and low levels of VEGF were related with <34 weeks of gestational age at delivery, whereas high levels of CUL1 and high levels VEGF were related with ≥34 weeks of gestational age at delivery. There was a negative correlation between the high ratios of p21/CUL1 and <34 weeks of gestational age at delivery in PE. Conclusions: Low levels of CUL1 and low levels VEGF and high ratios of p21/CUL1 were associated with <34 weeks of gestational age at delivery in PE. © 2021 Wolters Kluwer Medknow Publications. All rights reserved. |
Cullin 1; gestational age; p21; pre-eclampsia; vascular endothelial growth factor |
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Wolters Kluwer Medknow Publications |
09769668 |
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Article |
Q3 |
236 |
17374 |
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329 |
Ramlan A.A.W., Sugiharto A., Mutakim A. |
57195941841;57226310870;57226313039; |
Accuracy of pediatric advanced life support method for predicting the depth of endotracheal tube in indonesian children |
2021 |
Medical Journal of Indonesia |
30 |
2 |
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123 |
128 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111164254&doi=10.13181%2fmji.oa.203835&partnerID=40&md5=a6c7bb086d05bdb4faba3e211bf246af |
Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Ramlan, A.A.W., Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Sugiharto, A., Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Mutakim, A., Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
BACKGROUND The pediatric advanced life support (PALS) method can predict the depth of endotracheal tube (ETT) in pediatric patients easily, but it has limitations due to variations in the children’s characteristics, especially the racial consideration. This study compared the accuracy of ETT depth prediction based on the PALS methods in Indonesian children. METHODS Patients aged 0–12 years, who underwent elective surgery with oral intubation, were recruited consecutively based on their ages: 0–24 months and 25 months–12 years for this cross-sectional study in Cipto Mangunkusumo Hospital, Jakarta, Indonesia from June to August 2014. Bland–Altman analysis was used to compare the two measurement methods: PALS method to predict the ETT depth accuracy and auscultation method to confirm the position of the ETT. Furthermore, correlation analysis was done to examine the relationship of age, weight, height, and ETT internal diameter with ETT depth. RESULTS 50 patients were recruited in each group. Bland–Altman test of ETT depth in the 0–24 months age group showed a 1.18 cm mean difference from confirmation using the auscultation method (limits of agreement −0.71 to 3.08). The 25 months–12 years age group showed a 1.11 cm mean difference with limits of agreement were −0.95 to 3.17 from confirmation using the auscultation method. Age and weight had the strongest correlation value to ETT depth in the 25 months–12 years age group (R2 = 62.3%). CONCLUSIONS The PALS method is inaccurate for predicting ETT depth in Indonesian children aged 0–12 years old compared with the auscultation method. © 2021 Authors. |
Endotracheal tube; Pediatrics; Resuscitation |
atracurium besilate; accuracy; age; Article; body height; body weight; child; correlation analysis; cross-sectional study; elective surgery; endotracheal intubation; endotracheal tube internal diameter; female; general anesthesia; human; Indonesian; lung auscultation; major clinical study; male; pediatric advanced life support; physical parameters; racism; school child; tracheostomy |
Faculty of Medicine, Universitas Indonesia |
08531773 |
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Article |
Q4 |
164 |
21905 |
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330 |
Gondhowiardjo S., Hartanto S., Wirawan S., Jayalie V.F., Astiti I.A.P., Panigoro S.S., Sekarutami S.M., Rachman A., Bachtiar A. |
6508327402;57217201121;57226152890;57195939736;57226145786;56790104300;56576294500;15056701600;56683183900; |
Treatment delay of cancer patients in Indonesia: A reflection from a national referral hospital |
2021 |
Medical Journal of Indonesia |
30 |
2 |
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129 |
137 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110729832&doi=10.13181%2fmji.oa.204296&partnerID=40&md5=0ead2a2c9a147a42c0b4b82c1186bd1e |
Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Surgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Administration and Health Policy, Faculty of Public Health, Universitas Indonesia, Depok, Indonesia |
Gondhowiardjo, S., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Hartanto, S., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Wirawan, S., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Jayalie, V.F., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Astiti, I.A.P., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Panigoro, S.S., Department of Surgery, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Sekarutami, S.M., Department of Radiation Oncology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rachman, A., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Bachtiar, A., Department of Administration and Health Policy, Faculty of Public Health, Universitas Indonesia, Depok, Indonesia |
BACKGROUND Cancer is a complex disease requiring a multidisciplinary approach in establishing prompt diagnosis and treatment. Treatment in a timely manner is crucial for the outcomes. Hence, this study aimed to provide information on treatment delay including patient and provider delays and its associated factors. METHODS Cancer patients were recruited conveniently in the outpatient clinic of Department of Radiation Oncology, Cipto Mangunkusumo Hospital, Indonesia between May and August 2015. All patients were asked to fill a questionnaire and interviewed in this cross-sectional study. Treatment delay was explored and categorized into patient delay and provider delay. Patient delay could be happened before (patient-delay-1) or after (patient-delay-2) the patient was diagnosed with cancer. Provider delay could be due to physician, system-diagnosis, and system-treatment delays. RESULTS Among 294 patients, 86% patient had treatment delay. Patient delay was observed in 153 patients, and 43% of them had a history of alternative treatment. An older age (p = 0.047), lower educational level (p = 0.047), and history of alternative treatment (p<0.001) were associated with patient delay. Meanwhile, 214 patients had provider delay, and 9%, 36%, and 80% of them experienced physician, system-diagnosis, and system-treatment delays, respectively. All types of provider delay were associated with patient delay (p<0.001). CONCLUSIONS Most of the patient had treatment delay caused by either patient or provider. © 2021 Authors. |
Cancer; Indonesia; Treatment delay |
adolescent; adult; aged; Article; breast cancer; cancer patient; cancer radiotherapy; cross-sectional study; educational status; female; human; Indonesia; major clinical study; male; nasopharynx cancer; outpatient department; patient referral; physiotherapy; prevalence; questionnaire; radiation oncology; risk factor; therapy delay; uterine cervix cancer |
Faculty of Medicine, Universitas Indonesia |
08531773 |
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Article |
Q4 |
164 |
21905 |
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331 |
Irdam G.A., Febriyani, Rasyid N., Taher A. |
57194729795;57226319849;56245069300;7005269743; |
A systematic review of intracavernosal injection of mesenchymal stem cells for diabetic erectile dysfunction |
2021 |
Medical Journal of Indonesia |
30 |
2 |
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96 |
105 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110674329&doi=10.13181%2fmji.oa.204475&partnerID=40&md5=41f468eff0f07099de19a39da32f2a41 |
Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Irdam, G.A., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Febriyani, Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rasyid, N., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Taher, A., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
BACKGROUND As current erectile dysfunction (ED) treatments are limited, other treatment such as stem cells should be explored. Hence, this study aimed to review the sources, method of administration, and therapeutic effect of mesenchymal stem cells (MSCs) for diabetic ED treatment. METHODS All relevant articles regarding the use of MSCs for diabetic ED were searched in PubMed and Google Scholar databases from December 15, 2019 to January 1, 2020 published in the past 10 years. The keywords were “mesenchymal stem cells” and “diabetic ED”. The selection and critical appraisal of the studies were discussed. Diabetic ED was evaluated for functional and structural outcome. Functional outcome in animal studies was assessed by intracavernosal pressure/mean arterial pressure (ICP/ MAP) ratio, meanwhile the structural outcome was done microscopically. In human study, the assessments were done using international index of erectile function score (IIEF-5) to erection hardness score and penile Doppler ultrasonography. RESULTS There were 10 animal studies and 3 human studies. The studies used MSCs from adipose (n = 6), bone marrow (n = 4), placenta (n = 1), umbilical cord (n = 1), and muscle tissue (n = 1). The MSCs were administrated through intracavernosal injection in all studies. In all animal studies, functional outcome was improved, shown in higher ICP/MAP ratio. Microscopically, there were an increase of cavernosal endothelial cells, vascular endothelial growth factor, nitric oxide synthase, and smooth muscle cells. In human studies, IIEF-5 and erection hardness score were improved. Peak systolic velocity was also higher. CONCLUSIONS MSCs may be a promising therapy for diabetic ED; however, long-term safety concerns still need further investigations. © 2021, Faculty of Medicine, Universitas Indonesia. All rights reserved. |
Diabetes mellitus; Erectile dysfunction; Mesenchymal stem cells |
arterial pressure; Article; body mass; bone marrow; data extraction; DNA damage; Doppler ultrasonography; echography; erectile dysfunction; genomic instability; hardness; histochemistry; human; insulin sensitivity; International Index of Erectile Function; intracavernous pressure; mesenchymal stem cell; nonhuman; peak systolic velocity; placenta; questionnaire; shock wave therapy; smooth muscle cell; systematic review; umbilical cord |
Faculty of Medicine, Universitas Indonesia |
08531773 |
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Article |
Q4 |
164 |
21905 |
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344 |
Susantiningsih T., Makkiyah F.A., Thadeus M.S., Yulianti R., Hadi S. |
57192907038;57210232162;57226238484;57201696813;26534077400; |
Progressive acute liver damage induced by repeated 2-nitropropane: Focused on obese mice |
2021 |
Biomedical and Pharmacology Journal |
14 |
2 |
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695 |
700 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110971235&doi=10.13005%2fbpj%2f2172&partnerID=40&md5=d967f0ab42728fa05df28dd316a8f615 |
Faculty of Medicine, Universitas Pembangunan Nasional Veteran, Jakarta, 12450, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Chemistry, Universitas Lampung, Bandar Lampung, 35145, Indonesia |
Susantiningsih, T., Faculty of Medicine, Universitas Pembangunan Nasional Veteran, Jakarta, 12450, Indonesia, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Makkiyah, F.A., Faculty of Medicine, Universitas Pembangunan Nasional Veteran, Jakarta, 12450, Indonesia; Thadeus, M.S., Faculty of Medicine, Universitas Pembangunan Nasional Veteran, Jakarta, 12450, Indonesia; Yulianti, R., Faculty of Medicine, Universitas Pembangunan Nasional Veteran, Jakarta, 12450, Indonesia; Hadi, S., Department of Chemistry, Universitas Lampung, Bandar Lampung, 35145, Indonesia |
Obesity is linked to more deaths worldwide. In obesity, there will be a dysregulation of growth signals such as tumorigenesis. Despite the fact that obesity is tend to progress to acute liver damage, not many study using 2-nitropropane (2NP) as a hepatoxicity agent are undertaken especially in obese mice. This study aimed to determine the regime of 2NP that causes acute liver damage. This is an experimental research using a post-test control design group only, with 3 groups of mice ie O1 (obesity), O2+2-NP 1x (induced by 2NP 100 mg/kg BW once), and O2+2-NP 2x (induced by 2NP 100 mg/kg BW twice). At 10 weeks, rats were sacrificed and 100 mg liver tissue were collected for MDA, GSH, MnSOD and CAT enzymes analysis. Analysis statistics were performed by SPSS by one-way Anova and post hoc Tukey. MDA levels of mice were found to be increased in 2NP group than control (3.768 ± 0.407 nmol/ mg) (p < 0,01). Liver GSH, MnSOD and CAT levels of both single injection 2-NP and repeated injection 2-NP groups decreased compared to those of controls (p<0,01). Repeated injection of 2-NP worsen the acute liver damage in obese mice. © 2021 Oriental Scientific Publishing Company. All rights reserved. |
2-NP; CAT; GSH; MDA; MnSOD; Obesity |
2 nitropropane; catalase; glutathione peroxidase; ketamine; manganese superoxide dismutase; oxygen; reactive oxygen metabolite; superoxide dismutase; triacylglycerol; xylazine; analysis of variance; animal model; animal tissue; Article; body weight; carcinogenesis; centrifugation; controlled study; data analysis software; DNA damage; enzyme activity; liver injury; liver tissue; male; mouse; nonhuman; obesity; oxidative stress; post hoc analysis; protein content; repeated drug dose |
Oriental Scientific Publishing Company |
09746242 |
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Article |
Q4 |
191 |
19920 |
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345 |
Parikesit D., Witjaksono F., Mochtar C.A., Rasyid N., Hamid A.R.A.H. |
57163830300;57070455800;6506558321;56245069300;57202054669; |
Impact of metabolic syndrome on lower urinary tract symptoms in patients with benign prostate hyperplasia |
2021 |
Medical Journal of Indonesia |
30 |
2 |
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138 |
142 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110781511&doi=10.13181%2fmji.oa.214256&partnerID=40&md5=1ca9a518c25b6145dc4dc6f550d2833e |
Urology Medical Staff Group, Universitas Indonesia Hospital, Universitas Indonesia, West Java, Depok, Indonesia; Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Parikesit, D., Urology Medical Staff Group, Universitas Indonesia Hospital, Universitas Indonesia, West Java, Depok, Indonesia; Witjaksono, F., Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Mochtar, C.A., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rasyid, N., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Hamid, A.R.A.H., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
BACKGROUND Studies evaluating the relationship between metabolic syndrome (MetS) and lower urinary tract symptoms (LUTS) in men with benign prostate hyperplasia (BPH) are lacking in Indonesia. This study aimed to discover the association of LUTS and MetS in men with BPH. METHODS Subjects who underwent biopsy were recruited from Cipto Mangunkusumo Hospital, Jakarta, Indonesia from January 2014 to January 2018, but only men who had biopsy-proven BPH were included. Body mass index, waist circumference, fasting blood glucose, triglyceride, high-density lipoprotein, prostate volume (PV), and international prostate symptom score (IPSS) were collected before the biopsy. MetS criteria were based on the National Cholesterol Education Program Adult Treatment Panel III. IPSS was assessed for LUTS and consisted of irritative and obstructive symptoms and quality of life (QoL). Independent t-test or Mann–Whitney test was used to analyze numerical data. RESULTS Of 227 men with biopsy-proven BPH, 87 (38.3%) were diagnosed with MetS. PV was similar in men with or without MetS (54.4 [20.3–100] versus 49.9 [19.5–100] cm3, p = 0.239). Men with MetS generally had more LUTS (15 [1–30] versus 11 [0–35], p = 0.005), more irritative symptoms (8 [0–20] versus 6 [0–20], p = 0.007), and lower QoL (4 [0–6] versus 3 [0–6], p = 0.018). CONCLUSIONS BPH patients with MetS had greater LUTS, particularly irritative symptoms and QoL score. @ 2021 Authors. |
Benign prostate hyperplasia; Lower urinary tract symptoms; Metabolic syndrome |
high density lipoprotein cholesterol; triacylglycerol; Article; body mass; cross-sectional study; glucose blood level; human; human tissue; lower urinary tract symptom; major clinical study; male; metabolic syndrome X; prostate hypertrophy; prostate volume; quality of life; questionnaire; waist circumference |
Faculty of Medicine, Universitas Indonesia |
08531773 |
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Article |
Q4 |
164 |
21905 |
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346 |
Irawati Y., Gondhowiardjo T.D., Soebono H. |
57201260313;7801650709;6508242918; |
Efficacy and safety of platinum chain and gold weight implants for paralytic lagophthalmos: A systematic review |
2021 |
Medical Journal of Indonesia |
30 |
2 |
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106 |
115 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110572321&doi=10.13181%2fmji.oa.214683&partnerID=40&md5=1e4455ed4f7b0f8707adf603031b37e0 |
Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; JEC Eye Hospitals and Clinics, Jakarta, Indonesia; Department of Dermatovenereology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Dr. Sardjito Central General Hospital, Yogyakarta, Indonesia |
Irawati, Y., Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia, JEC Eye Hospitals and Clinics, Jakarta, Indonesia; Gondhowiardjo, T.D., Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia, JEC Eye Hospitals and Clinics, Jakarta, Indonesia; Soebono, H., Department of Dermatovenereology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Dr. Sardjito Central General Hospital, Yogyakarta, Indonesia |
BACKGROUND Surgery has been proposed as a treatment of paralytic lagophthalmos. However, no consensus has been reached on the best treatment. This study was aimed to investigate the efficacy and safety between platinum chain and gold weight implants to treat paralytic lagophthalmos. METHODS This study used all randomized controlled trials or observational studies (prospective or retrospective) using platinum chain and gold weight implants for paralytic lagophthalmos surgery that were published from 1990 to 2020 in the PubMed, Cochrane, and Google Scholar databases. Efficacy was indicated by the reduction of ≥3 in lagophthalmos, and safety was measured based on complications after surgery. RESULTS The efficacy of platinum chain and gold weight implants were 60–100% and 10–93.6%, respectively. The complications of platinum chain implant were 0–2.9% of extrusion and 0–3.3% of migration. However, gold weight implant had 0–13.3% of migration. CONCLUSIONS Both platinum chain and gold weight implants have similar efficacy to treat paralytic lagophthalmos. However, gold weight implant has a higher rate of complication. © 2021 Authors. |
Paralytic lagophthalmus; Prostheses and implants; Surgical techniques |
acoustic neuroma; Article; drug efficacy; drug safety; human; lagophthalmos; lid loading technique; paralytic lagophthalmos; systematic review; visual acuity |
Faculty of Medicine, Universitas Indonesia |
08531773 |
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Article |
Q4 |
164 |
21905 |
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351 |
Wijaya A.N., Margiana R., Kusumaningtyas S., Furqonita D. |
57225105688;56685900600;57193925307;57191057597; |
Comparison of decomposition rate of hind limbs of preserved mice with ethanol-glycerin and formaldehyde of advanced fixative solution |
2021 |
Anatomy and Cell Biology |
54 |
2 |
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225 |
231 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109181614&doi=10.5115%2facb.20.314&partnerID=40&md5=b084cc2abbf0ad3096da22401b79fe9b |
Undergraduate Program of Medical Education, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Anatomy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Wijaya, A.N., Undergraduate Program of Medical Education, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Margiana, R., Department of Anatomy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Kusumaningtyas, S., Department of Anatomy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Furqonita, D., Department of Anatomy, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Learning anatomy in medical school is still closely based on the use of cadavers. The burial of preserved cadaver poses a problem, specifically, it contaminates the soil with formalin. Many studies have been conducted to find an alternative fixative to update or modify formalin usage. One of them is ethanol-glycerin (EG), which suggests promising results. Despite that fact, there has yet to be any research comparing the decomposition rate between EG and formalin. This study is conducted to compare the rate of decomposition between the two fixative solutions, EG and 4% formalin on the hind limb of mice. The mice were first preserved using a standard primary fixative solution which is 10% formalin, following that procedure is preservation using advanced fixative solution, EG or 4% formalin. Upon completing the preservation steps, the mice were buried for 6 weeks and observed weekly. The stages of decomposition were assessed semi-quantitatively depending on its appearance. The hind limbs of mice that were fixed with EG solution managed to reach the last stage of decomposition, dry & remains, while the 4% formalin group of mice still remained in the previous stage, advanced decay. It is concluded that the mice hind limbs that have been previously preserved with EG advanced fixative solution has a faster decomposition rate compared to 4% formalin. Copyright © 2021. Anatomy & Cell Biology |
Burial; Glycerol; Mice; Preservation |
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Korean Association of Anatomists |
20933665 |
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Article |
Q2 |
366 |
12934 |
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363 |
Yo E.C., Witjaksono A.N., Fitriani D.Y., Werdhani R.A., Parikesit D. |
57213188908;57224351398;57224589606;57189088848;57163830300; |
Assessing webinar outcomes for health professionals: A perspective from Indonesia during coronavirus disease 2019 pandemic |
2021 |
Korean Journal of Medical Education |
33 |
2 |
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87 |
96 |
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3 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85107416703&doi=10.3946%2fKJME.2021.190&partnerID=40&md5=0cbaa0d20d5fdaa64a279a62d1943b06 |
Faculty of Medicine, Universitas Indonesia, Indonesia; Ophthalmology Medical Staff Group, Universitas Indonesia Hospital, Universitas Indonesia, Indonesia; Occupational Medicine Staff Group, Universitas Indonesia Hospital, Universita Indonesia, Depok, Indonesia; Department of Community Medicine, Faculty of Medicine, Jakarta, Indonesia; Urology Medical Staff Group, Universitas Indonesia Hospital, Universitas Indonesia, Depok, Indonesia; Universitas Indonesia Hospital, Pondok Cina, Beji, Depok City, West Java, 16424, Indonesia |
Yo, E.C., Faculty of Medicine, Universitas Indonesia, Indonesia; Witjaksono, A.N., Ophthalmology Medical Staff Group, Universitas Indonesia Hospital, Universitas Indonesia, Indonesia; Fitriani, D.Y., Occupational Medicine Staff Group, Universitas Indonesia Hospital, Universita Indonesia, Depok, Indonesia, Department of Community Medicine, Faculty of Medicine, Jakarta, Indonesia; Werdhani, R.A., Department of Community Medicine, Faculty of Medicine, Jakarta, Indonesia, Universitas Indonesia Hospital, Pondok Cina, Beji, Depok City, West Java, 16424, Indonesia; Parikesit, D., Urology Medical Staff Group, Universitas Indonesia Hospital, Universitas Indonesia, Depok, Indonesia |
Purpose: With the ongoing coronavirus disease 2019 (COVID-19) pandemic, health institutions and hospitals are increasingly relying on e-learning for continuing education. However, in many countries there is still limited data on the effectiveness of online learning particularly in the healthcare field. This study aims to evaluate whether webinar as a form of online educational intervention is satisfactory and effective for the continuing education of health professionals in Indonesia. Methods: We collected participants' demographic information including health profession, place of work, work unit, and year of graduation. There were six independent webinars included in this study. Webinar outcomes included satisfaction and learning scores. Regarding satisfaction, participants were told to complete a satisfaction survey and asked whether they would recommend the webinar to their colleagues. Regarding learning, information on their mean pre-test and post-test scores was collected. Results: A total of 3,607 health professionals were enrolled, with the highest participation in webinars about emergency cases and COVID-19 management. The response towards satisfaction was overwhelmingly positive. In all six webinars, post-test scores were statistically significantly higher than pre-test scores. Recently graduated physicians scored higher in learning than senior physicians, while place of work and work unit did not significantly affect the scores. Conclusion: The use of webinar for health professionals training in Indonesia was well-received amid the ongoing pandemic. In the future, health institutions and teaching hospitals should optimize the implementation of webinar training as it is associated with low cost, high flexibility, and less time commuting. © 2021 Korean Journal of Medical Education. All Rights Reserved. |
Continuing education; Covid-19; Health occupations; Online learning; Videoconferencing |
continuing education; cost benefit analysis; disease management; education; health care personnel; human; Indonesia; learning; pandemic; physician; procedures; satisfaction; teaching; teaching hospital; Cost-Benefit Analysis; COVID-19; Disease Management; Education, Continuing; Education, Distance; Educational Measurement; Health Personnel; Hospitals, Teaching; Humans; Indonesia; Learning; Pandemics; Personal Satisfaction; Physicians; SARS-CoV-2; Teaching |
Korean Society of Medical Education |
2005727X |
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34062640 |
Article |
Q4 |
175 |
21057 |
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