No records
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341 |
Rustamadji P., Wiyarta E., Bethania K.A., Kusmardi K. |
55321572200;57221521342;57226320454;56966625300; |
Potential of AKT2 expression as a predictor of lymph-node metastasis in invasive breast carcinoma of no special type |
2021 |
Journal of Pathology and Translational Medicine |
51 |
3 |
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271 |
278 |
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3 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111106383&doi=10.4132%2fjptm.2021.04.26&partnerID=40&md5=25c257f935b27c34728f8cc05fdeca15 |
Department of Anatomic Pathology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Anatomic Pathology, Drug Development Research Cluster, Human Cancer Research Center, IMERI, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Rustamadji, P., Department of Anatomic Pathology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Wiyarta, E., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Bethania, K.A., Department of Anatomic Pathology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Kusmardi, K., Department of Anatomic Pathology, Drug Development Research Cluster, Human Cancer Research Center, IMERI, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Background: Invasive breast carcinoma of no special type (IBC-NST) is the most common type of breast cancer and mainly causes regional lymph-node metastasis (LNM). We investigated the potential for AKT2 expression as a predictive biomarker for LNM in IBC-NST. Methods: Forty-eight paraffin blocks containing IBC-NST primary tumors were divided into two groups based on presence or absence of LNM. Age, tumor grade, tumor size, lymphovascular invasion (LVI), and AKT expression were assessed. AKT2 expression was assessed based on immunohistochemical staining, while other data were collected from archives. Results: Multiple logistic regression results showed that AKT2 expression and LVI were significantly associated with LNM (odds ratio [OR], 5.32; 95% confidence interval [CI], 1.42 to 19.93 and OR, 4.46; 95% CI, 1.17 to 16.97, respectively). AKT2 expression was able to discriminate against LNM (area under the receiver operating characteristic, 0.799 ± 0.063; 95% CI, 0.676 to 0.921) at an H-score cutoff of 104.62 (83.3% sensitivity, 62.5% specificity). Conclusions: AKT2 expression has potential as a predictor of LNM in IBC-NST. The H-score cutoff for AKT2 expression can be used as a classification guide in future studies. © 2021 The Korean Society of Pathologists/The Korean Society for Cytopathology. |
AKT2; Breast neoplasms; Immunohistochemistry; Metastasis |
biological marker; protein kinase B beta; adult; aged; Article; breast carcinoma; cancer grading; clinical article; confidence interval; controlled study; female; human; human tissue; immunohistochemistry; lymph vessel metastasis; multivariate logistic regression analysis; odds ratio; predictive value; protein expression; receiver operating characteristic; sensitivity and specificity; tumor invasion; tumor volume |
Seoul National University |
23837837 |
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Article |
Q2 |
684 |
7312 |
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342 |
Sparrow R., Agustina R., Bras H., Sheila G., Rieger M., Yumna A., Feskens E., Melse-Boonstra A. |
57205017055;57214141404;6701410272;57226298367;57205307158;55785938100;7005435520;6603151574; |
Adolescent Nutrition—Developing a Research Agenda for the Second Window of Opportunity in Indonesia |
2021 |
Food and Nutrition Bulletin |
42 |
1_suppl |
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S9 |
S20 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111099959&doi=10.1177%2f0379572120983668&partnerID=40&md5=69aa26692477cd183f7001a03be4e684 |
Development Economics Group, Wageningen University, Netherlands; International Institute of Social Studies, Erasmus University Rotterdam, Netherlands; Department of Nutrition, Faculty of Medicine, Universitas Indonesia - Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Human Nutrition Research Center, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Economic and Social History, University of Groningen, Netherlands; The SMERU Research Institute, Jakarta, Indonesia; Division of Human Nutrition and Health, Wageningen University, Netherlands |
Sparrow, R., Development Economics Group, Wageningen University, Netherlands, International Institute of Social Studies, Erasmus University Rotterdam, Netherlands; Agustina, R., Department of Nutrition, Faculty of Medicine, Universitas Indonesia - Dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia, Human Nutrition Research Center, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Bras, H., Economic and Social History, University of Groningen, Netherlands; Sheila, G., Human Nutrition Research Center, Indonesian Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Rieger, M., International Institute of Social Studies, Erasmus University Rotterdam, Netherlands; Yumna, A., The SMERU Research Institute, Jakarta, Indonesia; Feskens, E., Division of Human Nutrition and Health, Wageningen University, Netherlands; Melse-Boonstra, A., Division of Human Nutrition and Health, Wageningen University, Netherlands |
Background: Recently, adolescence has been identified as a second window of opportunity for the correction of nutritional inadequacies. However, there is a lack of knowledge on evidence-based integrated nutrition strategies for adolescents in Indonesia. Objective: To provide a research agenda and the prioritization of research actions to tackle outstanding knowledge gaps on adolescent nutrition in Indonesia. Methods: A preliminary set of research topics was listed based on a desk study of the academic literature and policy documents. Second, a stakeholder meeting was held to further identify and discuss research topics related to adolescent nutrition in Indonesia. Third, an online survey was conducted in which respondents were asked to indicate priority research themes for the next 3 to 5 years and to rank a total of 23 research questions. Results: Most (52%) of the respondents who returned the survey (n = 27) prioritize research on implementation and program evaluation, while 30% prefer descriptive and explanatory research, and 19% place priority with intervention and discovery research. However, when we followed up with specific topics for each of these broad research areas, a more nuanced picture emerged, with intervention and discovery research taking a more prominent standing. Conclusions: In order to support the design, implementation, and effectiveness of integrated nutrition programs for Indonesian adolescents, in-depth studies should question the best intervention strategies, modes of delivery, and long-term outcomes, while nationwide and disaggregated data should investigate associations and trends over time and identify vulnerable groups. © The Author(s) 2021. |
adolescents; Indonesia; nutrition; research agenda |
adolescence; nutrition; prioritization; stakeholder; adolescent; adolescent nutrition; article; clinical article; controlled study; female; human; Indonesia; Indonesian; male; program evaluation; Indonesia |
SAGE Publications Inc. |
03795721 |
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34282651 |
Article |
Q1 |
649 |
7743 |
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343 |
Agustina R., Meilianawati, Fenny, Atmarita, Suparmi, Susiloretni K.A., Lestari W., Pritasari K., Shankar A.H. |
57214141404;57224214324;57226280026;57191035215;57201388096;55920057100;57222081857;36490128600;7005442634; |
Psychosocial, Eating Behavior, and Lifestyle Factors Influencing Overweight and Obesity in Adolescents |
2021 |
Food and Nutrition Bulletin |
42 |
1_suppl |
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S72 |
S91 |
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3 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111017301&doi=10.1177%2f0379572121992750&partnerID=40&md5=430a97f5027110c908b0a552342f5ec8 |
Department of Nutrition, Faculty of Medicine, Universitas Indonesia —Dr. Cipto, Mangunkusumo General Hospital, Jakarta, Indonesia; Human Nutrition Research Center, Indonesian Medical Education and Research Institute (HNRC-IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; National Institute of Health Research and Development (NIHRD), Ministry of Health, Jakarta, Indonesia; Semarang Health Polytechnic Ministry of Health—Poltekkes Kemenkes Semarang, Indonesia; Directorate of Public Health, Ministry of Health, Jakarta, Indonesia; Centre for Tropical Medicine and Global Health, Oxford University, Oxford, United Kingdom |
Agustina, R., Department of Nutrition, Faculty of Medicine, Universitas Indonesia —Dr. Cipto, Mangunkusumo General Hospital, Jakarta, Indonesia, Human Nutrition Research Center, Indonesian Medical Education and Research Institute (HNRC-IMERI), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Meilianawati, Department of Nutrition, Faculty of Medicine, Universitas Indonesia —Dr. Cipto, Mangunkusumo General Hospital, Jakarta, Indonesia; Fenny, Department of Nutrition, Faculty of Medicine, Universitas Indonesia —Dr. Cipto, Mangunkusumo General Hospital, Jakarta, Indonesia; Atmarita, National Institute of Health Research and Development (NIHRD), Ministry of Health, Jakarta, Indonesia; Suparmi, National Institute of Health Research and Development (NIHRD), Ministry of Health, Jakarta, Indonesia; Susiloretni, K.A., Semarang Health Polytechnic Ministry of Health—Poltekkes Kemenkes Semarang, Indonesia; Lestari, W., Department of Nutrition, Faculty of Medicine, Universitas Indonesia —Dr. Cipto, Mangunkusumo General Hospital, Jakarta, Indonesia; Pritasari, K., Directorate of Public Health, Ministry of Health, Jakarta, Indonesia; Shankar, A.H., Centre for Tropical Medicine and Global Health, Oxford University, Oxford, United Kingdom |
Background: Adolescent overweight and obesity (AOO) is a global public health problem and risk for noncommunicable diseases. Understanding context-specific risks is crucial for interventions. Objective: Determine the prevalence of AOO in the Indonesian National Health Survey (INHS) 2013, assess the 5-year trend from 2013 to 2018, and identify risks. Methods: We selected adolescents aged 10 to 19 years (n = 174 290) from the INHS 2013 and used hierarchical logistic regression to identify gender-specific risks for those aged 15 to 19 years (n = 77 534). Change in AOO was assessed by comparison to INHS 2018 reports. Results: The national AOO prevalence increased over 5 years by 48% in young adolescents (13-15 years) and 85% in older ones (16-18 years). High prevalence areas included the urban location of Jakarta (20.9%) and the remote rural region of Papua (19.4%). Overall, AOO risks were being sedentary, male, lower education, married, younger adolescent, and school enrollment, with urban residence and higher wealth being persistent risks for all analyses. Data for depressive symptoms were available for older adolescents whose additional risks were being sedentary, depressive symptoms, and high-fat diet. Male risks were being sedentary and lower education, and female risks were being married, depressive symptoms, high-fat intake, and lower education. Higher intake of fruits and vegetables and fewer sweets did not protect against AOO if a high-fat diet was consumed. Conclusions: Adolescent overweight and obesity in Indonesia is rapidly increasing, especially in older adolescents and males, and with gender-specific risks. Customized multisectoral interventions to identify strategies for lifestyle change are urgently needed. © The Author(s) 2021. |
adolescents; depressive symptoms; nutrition; obesity; overweight |
adolescence; behavioral ecology; disease prevalence; factor analysis; health risk; lifestyle; noncommunicable disease; obesity; psychology; public health; Indonesia; Jakarta; Papua [(PRV) Indonesia] |
SAGE Publications Inc. |
03795721 |
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34282658 |
Article |
Q1 |
649 |
7743 |
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344 |
Susantiningsih T., Makkiyah F.A., Thadeus M.S., Yulianti R., Hadi S. |
57192907038;57210232162;57226238484;57201696813;26534077400; |
Progressive acute liver damage induced by repeated 2-nitropropane: Focused on obese mice |
2021 |
Biomedical and Pharmacology Journal |
14 |
2 |
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695 |
700 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110971235&doi=10.13005%2fbpj%2f2172&partnerID=40&md5=d967f0ab42728fa05df28dd316a8f615 |
Faculty of Medicine, Universitas Pembangunan Nasional Veteran, Jakarta, 12450, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Chemistry, Universitas Lampung, Bandar Lampung, 35145, Indonesia |
Susantiningsih, T., Faculty of Medicine, Universitas Pembangunan Nasional Veteran, Jakarta, 12450, Indonesia, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Makkiyah, F.A., Faculty of Medicine, Universitas Pembangunan Nasional Veteran, Jakarta, 12450, Indonesia; Thadeus, M.S., Faculty of Medicine, Universitas Pembangunan Nasional Veteran, Jakarta, 12450, Indonesia; Yulianti, R., Faculty of Medicine, Universitas Pembangunan Nasional Veteran, Jakarta, 12450, Indonesia; Hadi, S., Department of Chemistry, Universitas Lampung, Bandar Lampung, 35145, Indonesia |
Obesity is linked to more deaths worldwide. In obesity, there will be a dysregulation of growth signals such as tumorigenesis. Despite the fact that obesity is tend to progress to acute liver damage, not many study using 2-nitropropane (2NP) as a hepatoxicity agent are undertaken especially in obese mice. This study aimed to determine the regime of 2NP that causes acute liver damage. This is an experimental research using a post-test control design group only, with 3 groups of mice ie O1 (obesity), O2+2-NP 1x (induced by 2NP 100 mg/kg BW once), and O2+2-NP 2x (induced by 2NP 100 mg/kg BW twice). At 10 weeks, rats were sacrificed and 100 mg liver tissue were collected for MDA, GSH, MnSOD and CAT enzymes analysis. Analysis statistics were performed by SPSS by one-way Anova and post hoc Tukey. MDA levels of mice were found to be increased in 2NP group than control (3.768 ± 0.407 nmol/ mg) (p < 0,01). Liver GSH, MnSOD and CAT levels of both single injection 2-NP and repeated injection 2-NP groups decreased compared to those of controls (p<0,01). Repeated injection of 2-NP worsen the acute liver damage in obese mice. © 2021 Oriental Scientific Publishing Company. All rights reserved. |
2-NP; CAT; GSH; MDA; MnSOD; Obesity |
2 nitropropane; catalase; glutathione peroxidase; ketamine; manganese superoxide dismutase; oxygen; reactive oxygen metabolite; superoxide dismutase; triacylglycerol; xylazine; analysis of variance; animal model; animal tissue; Article; body weight; carcinogenesis; centrifugation; controlled study; data analysis software; DNA damage; enzyme activity; liver injury; liver tissue; male; mouse; nonhuman; obesity; oxidative stress; post hoc analysis; protein content; repeated drug dose |
Oriental Scientific Publishing Company |
09746242 |
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Article |
Q4 |
191 |
19920 |
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345 |
Parikesit D., Witjaksono F., Mochtar C.A., Rasyid N., Hamid A.R.A.H. |
57163830300;57070455800;6506558321;56245069300;57202054669; |
Impact of metabolic syndrome on lower urinary tract symptoms in patients with benign prostate hyperplasia |
2021 |
Medical Journal of Indonesia |
30 |
2 |
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138 |
142 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110781511&doi=10.13181%2fmji.oa.214256&partnerID=40&md5=1ca9a518c25b6145dc4dc6f550d2833e |
Urology Medical Staff Group, Universitas Indonesia Hospital, Universitas Indonesia, West Java, Depok, Indonesia; Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Parikesit, D., Urology Medical Staff Group, Universitas Indonesia Hospital, Universitas Indonesia, West Java, Depok, Indonesia; Witjaksono, F., Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Mochtar, C.A., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Rasyid, N., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Hamid, A.R.A.H., Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
BACKGROUND Studies evaluating the relationship between metabolic syndrome (MetS) and lower urinary tract symptoms (LUTS) in men with benign prostate hyperplasia (BPH) are lacking in Indonesia. This study aimed to discover the association of LUTS and MetS in men with BPH. METHODS Subjects who underwent biopsy were recruited from Cipto Mangunkusumo Hospital, Jakarta, Indonesia from January 2014 to January 2018, but only men who had biopsy-proven BPH were included. Body mass index, waist circumference, fasting blood glucose, triglyceride, high-density lipoprotein, prostate volume (PV), and international prostate symptom score (IPSS) were collected before the biopsy. MetS criteria were based on the National Cholesterol Education Program Adult Treatment Panel III. IPSS was assessed for LUTS and consisted of irritative and obstructive symptoms and quality of life (QoL). Independent t-test or Mann–Whitney test was used to analyze numerical data. RESULTS Of 227 men with biopsy-proven BPH, 87 (38.3%) were diagnosed with MetS. PV was similar in men with or without MetS (54.4 [20.3–100] versus 49.9 [19.5–100] cm3, p = 0.239). Men with MetS generally had more LUTS (15 [1–30] versus 11 [0–35], p = 0.005), more irritative symptoms (8 [0–20] versus 6 [0–20], p = 0.007), and lower QoL (4 [0–6] versus 3 [0–6], p = 0.018). CONCLUSIONS BPH patients with MetS had greater LUTS, particularly irritative symptoms and QoL score. @ 2021 Authors. |
Benign prostate hyperplasia; Lower urinary tract symptoms; Metabolic syndrome |
high density lipoprotein cholesterol; triacylglycerol; Article; body mass; cross-sectional study; glucose blood level; human; human tissue; lower urinary tract symptom; major clinical study; male; metabolic syndrome X; prostate hypertrophy; prostate volume; quality of life; questionnaire; waist circumference |
Faculty of Medicine, Universitas Indonesia |
08531773 |
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Article |
Q4 |
164 |
21905 |
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346 |
Irawati Y., Gondhowiardjo T.D., Soebono H. |
57201260313;7801650709;6508242918; |
Efficacy and safety of platinum chain and gold weight implants for paralytic lagophthalmos: A systematic review |
2021 |
Medical Journal of Indonesia |
30 |
2 |
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106 |
115 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110572321&doi=10.13181%2fmji.oa.214683&partnerID=40&md5=1e4455ed4f7b0f8707adf603031b37e0 |
Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; JEC Eye Hospitals and Clinics, Jakarta, Indonesia; Department of Dermatovenereology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Dr. Sardjito Central General Hospital, Yogyakarta, Indonesia |
Irawati, Y., Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia, JEC Eye Hospitals and Clinics, Jakarta, Indonesia; Gondhowiardjo, T.D., Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia, JEC Eye Hospitals and Clinics, Jakarta, Indonesia; Soebono, H., Department of Dermatovenereology, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Dr. Sardjito Central General Hospital, Yogyakarta, Indonesia |
BACKGROUND Surgery has been proposed as a treatment of paralytic lagophthalmos. However, no consensus has been reached on the best treatment. This study was aimed to investigate the efficacy and safety between platinum chain and gold weight implants to treat paralytic lagophthalmos. METHODS This study used all randomized controlled trials or observational studies (prospective or retrospective) using platinum chain and gold weight implants for paralytic lagophthalmos surgery that were published from 1990 to 2020 in the PubMed, Cochrane, and Google Scholar databases. Efficacy was indicated by the reduction of ≥3 in lagophthalmos, and safety was measured based on complications after surgery. RESULTS The efficacy of platinum chain and gold weight implants were 60–100% and 10–93.6%, respectively. The complications of platinum chain implant were 0–2.9% of extrusion and 0–3.3% of migration. However, gold weight implant had 0–13.3% of migration. CONCLUSIONS Both platinum chain and gold weight implants have similar efficacy to treat paralytic lagophthalmos. However, gold weight implant has a higher rate of complication. © 2021 Authors. |
Paralytic lagophthalmus; Prostheses and implants; Surgical techniques |
acoustic neuroma; Article; drug efficacy; drug safety; human; lagophthalmos; lid loading technique; paralytic lagophthalmos; systematic review; visual acuity |
Faculty of Medicine, Universitas Indonesia |
08531773 |
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Article |
Q4 |
164 |
21905 |
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347 |
Moegni F., Ocsilia Wengkang I.F. |
55450456100;57226112377; |
Correlation of levator ani muscle strength measurement between Modified Oxford Grading Scale and perineometer on pelvic organ prolapse patient |
2021 |
Urogynaecologia International Journal |
33 |
1 |
268 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110513972&doi=10.4081%2fUIJ.2021.268&partnerID=40&md5=f4aa2afc9d600b8716b8e0217ad613a6 |
Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Moegni, F., Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Ocsilia Wengkang, I.F., Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Pelvic Organ Prolapse (POP) is a debilitating condition affecting about half of all women aged of more than 60 years globally. Reduced levator ani muscle strength in POP is associated with worse symptoms and prognosis. Measurement of levator ani muscle strength can be done with several tools such as perineometer and digital palpation. However, there is currently no study regarding conformity between tests. The aim of this study is to determine the correlation between tests in POP patients. An analytic observational study using cross sectional design was done to determine conformity between perineometer and digital examination using Modified Oxford Grading Scale (MOS) in Dr Cipto Mangunkusumo National General Hospital, Indonesia during the period of July, 2018 to June, 2020. Correlation between tests was determined using Spearman test. Cut-off of perineometer reading for each MOS score was also determined. A total of 110 subjects examined with both perineometer and digital palpation were recruited to the study. Positive correlation was observed between perineometer reading and Modified Oxford Grading Scale (r = 0.790, p < 0.001). According to the result, values between 0.01 – 9.64 cmH2O correspond to very weak pressure (MOS 1); 9.65 – 22.49 cmH2O represent weak pressure (MOS 2); 22.5 – 35.24 cmH2O represent moderate pressure (MOS 3); ≥ 35.25 cmH2O represent good pressure (MOS 4). There was a strong correlation between MOS and perineometer result for measuring levator ani strength in POP patients. Non ©Copyright: the Author(s), 2021 Licensee PAGEPress, Italy |
Levator ani muscle strength; Modified Oxford Grading Scale, pelvic organ prolapse; Perineometer |
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Page Press Publications |
20388314 |
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Article |
Q4 |
103 |
30394 |
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348 |
Djuardi Y., Lazarus G., Stefanie D., Fahmida U., Ariawan I., Supali T. |
6507800820;57214599425;57193121018;14420783500;8840573400;6602742029; |
Soil-transmitted helminth infection, anemia, and malnutrition among preschool-age children in nangapanda subdistrict, indonesia |
2021 |
PLoS Neglected Tropical Diseases |
15 |
6 |
e0009506 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110433985&doi=10.1371%2fjournal.pntd.0009506&partnerID=40&md5=acf6b372e3919f6422f75ae7d13a1c91 |
Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Southeast Asian Ministers of Education Organization Regional Centre for Food and Nutrition (SEAMEO RECFON), Pusat Kajian Gizi Regional Universitas Indonesia, Jakarta, Indonesia; Department of Biostatistics and Population Studies, Faculty of Public Health, Universitas Indonesia, Depok, Indonesia |
Djuardi, Y., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Lazarus, G., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Stefanie, D., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Fahmida, U., Southeast Asian Ministers of Education Organization Regional Centre for Food and Nutrition (SEAMEO RECFON), Pusat Kajian Gizi Regional Universitas Indonesia, Jakarta, Indonesia; Ariawan, I., Department of Biostatistics and Population Studies, Faculty of Public Health, Universitas Indonesia, Depok, Indonesia; Supali, T., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Background Soil-transmitted helminth (STH) infections are still prevalent in Indonesia, with roughly one-third of infected population being preschool-age children (PSC), which are generally at higher risk of morbidity such as malnutrition and anemia. This study aimed to investigate the association of STH infections with nutritional status and anemia among PSC in Nangapanda subdistrict, Ende, East Nusa Tenggara. Methods A cross-sectional survey involving PSC ranging from 12 to 59 months old from Nangapanda subdistrict, Ende district, East Nusa Tenggara was performed. Socio-demographic, breastfeeding, and complementary feeding information was obtained from structured questionnaires, while nutritional and anemia status was determined from anthropometry and hemoglobin measurements, respectively. Anthropometric z-scores were calculated based on the World Health Organization 2006 standards and stool samples were examined using Kato-Katz method. Results A total of 393 PSC randomly selected from 22 villages were examined. The prevalence of underweight, stunting, wasting, and anemia were 33.1%, 40.2%, 17.1%, and 60.3%, respectively. STH infection, predominated by Ascaris lumbricoides, was found in 160 (58.8%) PSC. Single STH infection, but not multiple infection, was independently associated with a lower risk of anemia (odds ratio [OR] 0.320, 95% confidence interval [CI]: 0.126– 0.809, p = 0.016). Similar association with anemia was also found on mild STH infection (OR 0.318 [95% CI: 0.114–0.887], p = 0.029). On the other hand, younger children were found to have a higher risk of anemia and stunting. None of the examined variables were independently associated with underweight and wasting. Conclusion STH infection as well as anemia and malnutrition were prevalent in this region. However in this study, current STH infections seemed to have minimal negative impact on children’s nutritional status. © 2021 Djuardi et al. |
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edetic acid; hemoglobin; hemoglobin; anemia; anthropometry; antiretroviral therapy; Article; body mass; breast feeding; child; complementary feeding; controlled study; cross-sectional study; disorder of sex development; endoscopic retrograde cholangiopancreatography; feces analysis; female; flotation; food frequency questionnaire; food intake; helminthiasis; human; major clinical study; male; malnutrition; mass spectrometry; morbidity; nutritional status; obesity; preschool child; questionnaire; randomized controlled trial; risk factor; Strongyloides stercoralis; structured questionnaire; stunting; underweight; vitamin intake; vitamin supplementation; World Health Organization; anemia; animal; Ascaris lumbricoides; growth disorder; helminthiasis; Indonesia; infant; malnutrition; parasitolo |
Public Library of Science |
19352727 |
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34138863 |
Article |
Q1 |
1990 |
1322 |
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349 |
Shukla A., Shreshtha A., Mukund A., Bihari C., Eapen C.E., Han G., Deshmukh H., Cua I.H.Y., Lesmana C.R.A., Al Meshtab M., Kage M., Chaiteeraki R., Treeprasertsuk S., Giri S., Punamiya S., Paradis V., Qi X., Sugawara Y., Abbas Z., Sarin S.K. |
36652088000;57225888142;15071187800;49860931800;7003684081;24741087200;7003527959;7801457234;8977683000;57225918379;57225886245;57225920095;57077082800;57221051314;23670642900;57195572516;35339923000;57197741618;35572268700;57220191468; |
Budd-Chiari syndrome: consensus guidance of the Asian Pacific Association for the study of the liver (APASL) |
2021 |
Hepatology International |
15 |
3 |
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531 |
567 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109622410&doi=10.1007%2fs12072-021-10189-4&partnerID=40&md5=727d2318980fa73306867439390cc762 |
Department of Gastroenterology, King Edward Memorial Hospital and Seth Gordhandas Sunderdas Medical College, Mumbai, India; Alka Hospital, Kathmandu, Nepal; Institute of Liver and Biliary Sciences, New Delhi, India; Christian Medical College, Vellore, India; Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xian, China; Dean and Head of Radiology, King Edward Memorial Hospital and Seth Gordhandas Sunderdas Medical College, Mumbai, India; Institute of Digestive and Liver Diseases, St Lukes Medical Center, Global City, Philippines; Dr. Cipto Mangunkusumo National General Hospital, Universitas Indonesia, Jakarta, Indonesia; Digestive Disease & GI Oncology Center, Medistra Hospital, Jakarta, Indonesia; Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh; Center for Innovative Cancer Therapy, Kurume University Research, 67 Asahi-machi, Kurume, 830-0011, Japan; Division of Gastroenterology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; Vascular and Interventional Radiology, Tan Tock Seng Hospital, Singapore, Singapore; Dpt dAnatomie Pathologique, Hôpital Beaujon, 100 bd du Gal Leclerc, Clichy, 92110, France; General Hospital of Northern Theater Command (formerly General Hospital of Shenyang Military Area), No. 83 Wenhua Road, Shenyang, China; Department of Transplantation and Pediatric Surgery, Kumamoto University, Kumamoto, Japan; Department of Hepatogastroenterology, Dr. Ziauddin University Hospital Clifton, Karachi, Pakistan |
Shukla, A., Department of Gastroenterology, King Edward Memorial Hospital and Seth Gordhandas Sunderdas Medical College, Mumbai, India; Shreshtha, A., Alka Hospital, Kathmandu, Nepal; Mukund, A., Institute of Liver and Biliary Sciences, New Delhi, India; Bihari, C., Institute of Liver and Biliary Sciences, New Delhi, India; Eapen, C.E., Christian Medical College, Vellore, India; Han, G., Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xian, China; Deshmukh, H., Dean and Head of Radiology, King Edward Memorial Hospital and Seth Gordhandas Sunderdas Medical College, Mumbai, India; Cua, I.H.Y., Institute of Digestive and Liver Diseases, St Lukes Medical Center, Global City, Philippines; Lesmana, C.R.A., Dr. Cipto Mangunkusumo National General Hospital, Universitas Indonesia, Jakarta, Indonesia, Digestive Disease & GI Oncology Center, Medistra Hospital, Jakarta, Indonesia; Al Meshtab, M., Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh, Center for Innovative Cancer Therapy, Kurume University Research, 67 Asahi-machi, Kurume, 830-0011, Japan; Kage, M., Department of Gastroenterology, King Edward Memorial Hospital and Seth Gordhandas Sunderdas Medical College, Mumbai, India; Chaiteeraki, R., Division of Gastroenterology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; Treeprasertsuk, S., Division of Gastroenterology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; Giri, S., Department of Gastroenterology, King Edward Memorial Hospital and Seth Gordhandas Sunderdas Medical College, Mumbai, India; Punamiya, S., Vascular and Interventional Radiology, Tan Tock Seng Hospital, Singapore, Singapore; Paradis, V., Dpt dAnatomie Pathologique, Hôpital Beaujon, 100 bd du Gal Leclerc, Clichy, 92110, France; Qi, X., General Hospital of Northern Theater Command (formerly General Hospital of Shenyang Military Area), No. 83 Wenhua Road, Shenyang, China; Sugawara, Y., Department of Transplantation and Pediatric Surgery, Kumamoto University, Kumamoto, Japan; Abbas, Z., Department of Hepatogastroenterology, Dr. Ziauddin University Hospital Clifton, Karachi, Pakistan; Sarin, S.K., Institute of Liver and Biliary Sciences, New Delhi, India |
Budd Chiari syndrome (BCS) is a diverse disease with regard to the site of obstruction, the predisposing thrombophilic disorders and clinical presentation across the Asia-Pacific region. The hepatic vein ostial stenosis and short segment thrombosis are common in some parts of Asia-Pacific region, while membranous obstruction of the vena cava is common in some and complete thrombosis of hepatic veins in others. Prevalence of myeloproliferative neoplasms and other thrombophilic disorders in BCS varies from region to region and with different sites of obstruction. This heterogeneity also raises several issues and dilemmas in evaluation and approach to management of a patient with BCS. The opportunity to recanalize hepatic vein in patients with hepatic vein ostial stenosis or inferior vena cava stenting or pasty among those membranous obstruction of the vena cava is a unique opportunity in the Asia–Pacific region to restore hepatic outflow closely mimicking physiology. In order to address these issues arising out of the diversity as well as the unique features in the region, the Asia Pacific Association for Study of Liver has formulated these guidelines for clinicians. © 2021, Asian Pacific Association for the Study of the Liver. |
Ascites; Budd Chiari syndrome; Hepatic vein stenting; Hepatocellular carcinoma; HVOTO; Liver biopsy; Liver transplant; MOVC; Portal hypertension; TIPS |
calreticulin; low molecular weight heparin; acute liver failure; acute on chronic liver failure; angioplasty; anticoagulant therapy; Article; Asia; blood clot lysis; blood clotting; Budd Chiari syndrome; cancer chemotherapy; chemoembolization; clinical feature; computer assisted tomography; Doppler flowmetry; female fertility; follow up; groups by age; hepatocellular adenoma; human; hyperhomocysteinemia; incidence; inferior cava vein; liver adenoma; liver cell carcinoma; liver nodule; liver transplantation; liver vein; nodular hyperplasia; nuclear magnetic resonance imaging; pathogenesis; postoperative complication; practice guideline; pregnancy; preoperative evaluation; prognosis; recanalization; risk factor; stent thrombosis; survival factor; thrombophilia; transjugular intrahepatic port |
Springer |
19360533 |
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34240318 |
Article |
Q2 |
1304 |
2874 |
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350 |
Herawati F., Jaelani A.K., Wijono H., Rahem A., Setiasih, Yulia R., Andrajati R., Soemantri D. |
57194722742;57372559200;57222260570;57204655643;57209025002;56768083700;9940247700;36640659100; |
Antibiotic stewardship knowledge and belief differences among healthcare professionals in hospitals: A survey study |
2021 |
Heliyon |
7 |
6 |
e07377 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109492428&doi=10.1016%2fj.heliyon.2021.e07377&partnerID=40&md5=5c399c28320a996c1e4e405a6c2d8169 |
Department of Clinical and Community Pharmacy, Faculty of Pharmacy, Universitas Surabaya, Surabaya, 60293, Indonesia; Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia; Department of Pharmacy, RSUD Bangil, Pasuruan, 67153, Indonesia; Faculty of Medicine, Universitas Surabaya, Surabaya, 60293, Indonesia; Community Pharmacy Department, Faculty of Pharmacy, Airlangga University, Surabaya, 60115, Indonesia; Laboratory for Developmental Psychology, Faculty of Psychology, Universitas Surabaya, Surabaya, 60293, Indonesia; Department of Medical Education, Faculty of Medicine, Universitas Indonesia, Depok, 16424, Indonesia |
Herawati, F., Department of Clinical and Community Pharmacy, Faculty of Pharmacy, Universitas Surabaya, Surabaya, 60293, Indonesia, Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia; Jaelani, A.K., Department of Pharmacy, RSUD Bangil, Pasuruan, 67153, Indonesia; Wijono, H., Faculty of Medicine, Universitas Surabaya, Surabaya, 60293, Indonesia; Rahem, A., Community Pharmacy Department, Faculty of Pharmacy, Airlangga University, Surabaya, 60115, Indonesia; Setiasih, Laboratory for Developmental Psychology, Faculty of Psychology, Universitas Surabaya, Surabaya, 60293, Indonesia; Yulia, R., Department of Clinical and Community Pharmacy, Faculty of Pharmacy, Universitas Surabaya, Surabaya, 60293, Indonesia; Andrajati, R., Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia; Soemantri, D., Department of Medical Education, Faculty of Medicine, Universitas Indonesia, Depok, 16424, Indonesia |
Background: Collaborative practice in healthcare has been recommended to improve the quality of antimicrobial stewardship interventions, a behavioral change in antimicrobial use. Insufficient knowledge regarding antibiotic resistance, the fear of complications from infections, and how providers perceive antibiotic use and resistance are likely to influence prescribing behavior. This study's objective was to identify the knowledge and belief healthcare professionals' differences about antibiotic stewardship. Methods: This cross-sectional survey study of three hospitals in the East Java province, Indonesia utilized a 43-item questionnaire to assess antimicrobial stewardship knowledge and belief. There were 12 knowledge questions (total possible score: 12) and 31 belief questions (total possible score: 155). The Kuder Richardson 20 (KR-20) and Cronbach alpha values of the questionnaire were 0.54 and 0.92, respectively. Results: Out of the 257 respondents, 19% (48/257) had a low scores of knowledge, and 39% (101/257) had low scores on belief about antibiotic stewardship (101/257). Most midwives had a low scores on knowledge (25/61) and low scores on belief (46/61). Respondents with high scores on belief were 17% (10/59) physicians, 15% (4/27) pharmacists, 8% (5/65) nurses, and 3% (2/61) midwives. Conclusion: Among healthcare professionals, knowledge and belief differences concerning antibiotic stewardship vary widely. These differences will affect their capability, behavior, and contribution to the healthcare team collaboration and performance. Further studies are needed to evaluate the correlation between the level of inter-professional collaboration and the quality of the antibiotic stewardship implementation. © 2021 The Author(s) |
Antibiotic stewardship; Belief; Knowledge |
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Elsevier Ltd |
24058440 |
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Article |
Q1 |
455 |
10919 |
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