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454 |
Siste K., Hanafi E., Sen L.T., Wahjoepramono P.O.P., Kurniawan A., Yudistiro R. |
55644113100;56737010600;57219034101;57216247534;56521213900;57041205200; |
Erratum: Potential correlates of internet gaming disorder among Indonesian medical students: Cross-sectional study (Journal of Medical Internet Research (2021) 23:4 (e25468) DOI: 10.2196/25468) |
2021 |
Journal of Medical Internet Research |
23 |
4 |
e29790 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105627812&doi=10.2196%2f29790&partnerID=40&md5=81d33d24852e7aee04557d088a3802cd |
Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Faculty of Medicine, Universitas Pelita Harapan, Siloam Hospitals, Tangerang, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Pelita Harapan, Siloam Hospital, Tangerang, Indonesia |
Siste, K., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Hanafi, E., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Sen, L.T., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Wahjoepramono, P.O.P., Faculty of Medicine, Universitas Pelita Harapan, Siloam Hospitals, Tangerang, Indonesia; Kurniawan, A., Department of Internal Medicine, Faculty of Medicine, Universitas Pelita Harapan, Siloam Hospital, Tangerang, Indonesia; Yudistiro, R., Faculty of Medicine, Universitas Pelita Harapan, Siloam Hospitals, Tangerang, Indonesia |
In “Potential Correlates of Internet Gaming Disorder Among Indonesian Medical Students: Cross-sectional Study” (J Med Internet Res 2021;23(4):e25468) the authors noted two errors. Due to a system error, the name of one author, Andree Kurniawan, was replaced with the name of another author on the paper, Ryan Yudistiro. In the originally published paper, the order of authors was listed as follows: Kristiana Siste; Enjeline Hanafi; Lee Thung Sen; Petra Octavian Perdana Wahjoepramono; Ryan Yudistiro; Ryan Yudistiro This has been corrected to: Kristiana Siste; Enjeline Hanafi; Lee Thung Sen; Petra Octavian Perdana Wahjoepramono; Andree Kurniawan; Ryan Yudistiro In the originally published paper, the ORCID number of author Ryan Yudistiro was incorrectly published as follows: 0000-0002-5219-9029 This has been corrected to: 0000-0003-1418-2661 The correction will appear in the online version of the paper on the JMIR Publications website on April 21, 2021, together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories. © Kristiana Siste, Enjeline Hanafi, Lee Thung Sen, Petra Octavian Perdana Wahjoepramono, Andree Kurniawan, Ryan Yudistiro. |
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erratum |
JMIR Publications Inc. |
14388871 |
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33882024 |
Erratum |
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1446 |
2408 |
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457 |
Rozaliyani A., Setianingrum F., Azahra S., Abdullah A., Fatril A.E., Rosianawati H., Burhan E., Handayani D., Arifin A.R., Zaini J., Tugiran M., Adawiyah R., Syam R., Wibowo H., Wahyuningsih R., Kosmidis C., Denning D.W. |
57203065912;57203061705;57219977463;57223138415;57223130315;57220203100;36058554600;57219413838;57223139966;57221833355;57218291154;57208658742;57218290535;57217690943;6507268400;16834840500;57223404509; |
Performance of ldbio aspergillus wb and ict antibody detection in chronic pulmonary aspergillosis |
2021 |
Journal of Fungi |
7 |
4 |
311 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105015900&doi=10.3390%2fjof7040311&partnerID=40&md5=d403a899e390ae45f6c1071eeb2d4832 |
Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, 13230, Indonesia; MH Thamrin Hospital, Jakarta, 10440, Indonesia; Department of Parasitology, Faculty of Medicine, Universitas Kristen, Jakarta, 13530, Indonesia; Manchester Academic Health Science Centre, Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, School of Biological Sciences, Medicine and Health, University of Manchester, Manchester, M23 9LT, United Kingdom |
Rozaliyani, A., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Setianingrum, F., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Azahra, S., Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Abdullah, A., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Fatril, A.E., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Rosianawati, H., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, 13230, Indonesia; Burhan, E., Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia, Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, 13230, Indonesia; Handayani, D., Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia, Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, 13230, Indonesia; Arifin, A.R., Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia, MH Thamrin Hospital, Jakarta, 10440, Indonesia; Zaini, J., Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia, Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, 13230, Indonesia; Tugiran, M., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Adawiyah, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Syam, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Wibowo, H., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Wahyuningsih, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia, Department of Parasitology, Faculty of Medicine, Universitas Kristen, Jakarta, 13530, Indonesia; Kosmidis, C., Manchester Academic Health Science Centre, Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, School of Biological Sciences, Medicine and Health, University of Manchester, Manchester, M23 9LT, United Kingdom; Denning, D.W., Manchester Academic Health Science Centre, Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, School of Biological Sciences, Medicine and Health, University of Manchester, Manchester, M23 9LT, United Kingdom |
The detection of Aspergillus antibody has a key role in the diagnosis of chronic pulmonary as-pergillosis. Western blot (WB) and immunochromatography (ICT) lateral flow detection of Aspergillus antibody can be used as confirmatory and screening assays but their comparative performance in TB patients is not known. This study investigated the performance of these assays among 88 post-tuberculosis patients with suspected CPA. Sensitivity, specificity, receiver operating curve (ROC), area under-curve (AUC) and the agreement between two assays were evaluated. Both WB and ICT showed good sensitivity (80% and 85%, respectively) for detection of Aspergillus antibodies. Substantial agreement (0.716) between these assays was also obtained. The highest AUC result (0.804) was achieved with the combination of WB and ICT. The global intensity of WB correlated with the severity of symptoms in CPA group (p = 0.001). The combination of WB and ICT may increase specificity in CPA diagnosis. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Chronic pulmonary aspergillosis; Immunochromatography; Western blot |
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MDPI AG |
2309608X |
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Article |
Q1 |
1702 |
1800 |
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461 |
Prasetyo M., Adistana I.M., Setiawan S.I. |
57192905252;57223019188;57195939543; |
Tuberculous septic arthritis of the hip with large abscess formation mimicking soft tissue tumors: A case report |
2021 |
Heliyon |
7 |
4 |
e06815 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85104438407&doi=10.1016%2fj.heliyon.2021.e06815&partnerID=40&md5=e543449bd0c6c3d5e0c816cffc92a0e4 |
Department of Radiology, Faculty of Medicine Universitas Indonesia – Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia |
Prasetyo, M., Department of Radiology, Faculty of Medicine Universitas Indonesia – Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Adistana, I.M., Department of Radiology, Faculty of Medicine Universitas Indonesia – Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Setiawan, S.I., Department of Radiology, Faculty of Medicine Universitas Indonesia – Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia |
Background: Tuberculous septic arthritis is an infection that occurs inside the joint or synovial fluid and joint tissues caused by Mycobacterium tuberculosis. It may show wide variability of clinical symptoms and imaging appearance, ranging from asymptomatic with a normal radiographic examination to severe joint pain along with joint destruction, osteomyelitis, and abscess formation. This article presents radiographic and MR imaging appearance from a case of tuberculous septic arthritis with large abscess formation mimicking soft tissue tumor. Case presentation: We reported a 32-year-old female with a slowly enlarging lump on her right proximal thigh within the last 4 months along with slowly progressing joint pain. Both radiographic and MR images showed destruction of the femoral head and acetabular roof, with a formation of large rim-enhanced abscess that extending superficially and distally until mid-thigh. The patient underwent open drainage surgery and excisional biopsy. Histopathological examination showed chronic granulomatous inflammation caused by tuberculous infection. Conclusion: MR imaging combined with radiographic and clinical information played a very important role in the diagnosis of tuberculous septic arthritis with abscess, and to differentiate it from soft tissue neoplasms. © 2021 The Author(s) |
Abscess; Infectious arthritis; Septic arthritis; Tuberculosis |
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Elsevier Ltd |
24058440 |
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Article |
Q1 |
455 |
10919 |
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462 |
Siste K., Hanafi E., Sen L.T., Wahjoepramono P.O.P., Kurniawan A., Yudistiro R. |
55644113100;56737010600;57219034101;57216247534;56521213900;57041205200; |
Potential correlates of internet gaming disorder among Indonesian medical students: Cross-sectional study |
2021 |
Journal of Medical Internet Research |
23 |
4 |
e25468 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85104418234&doi=10.2196%2f25468&partnerID=40&md5=9877dd97d733cb4ea58465ec70c69a79 |
Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Faculty of Medicine, Universitas Pelita Harapan, Siloam Hospitals, Tangerang, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Pelita, Harapan Siloam Hospital, Tangerang, Indonesia |
Siste, K., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Hanafi, E., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Sen, L.T., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Wahjoepramono, P.O.P., Faculty of Medicine, Universitas Pelita Harapan, Siloam Hospitals, Tangerang, Indonesia; Kurniawan, A., Department of Internal Medicine, Faculty of Medicine, Universitas Pelita, Harapan Siloam Hospital, Tangerang, Indonesia; Yudistiro, R., Faculty of Medicine, Universitas Pelita Harapan, Siloam Hospitals, Tangerang, Indonesia |
Background: Internet gaming disorder has been a controversial topic for nearly a decade. Although internet addiction has been studied in medical students, there is a paucity of evidence regarding internet gaming disorder. Previous studies in Indonesia explored only the prevalence rate and characteristics. Objective: This study aimed to determine the prevalence rate of internet gaming disorder and correlations between internet gaming disorder, temperament, and psychopathology among Indonesian medical students. Methods: A cross-sectional study was performed from August 2019 to September 2019 using total and convenience sampling at a private university and a public university, respectively. The study variables were measured using the Indonesian version of the 10-item Internet Gaming Disorder Test, the Temperament and Character Inventory, and the Symptoms Checklist 90. Chi-square and logistic regression analyses were conducted to examine the relationships between demographic factors, temperament, psychopathology, and the presence of internet gaming disorder. Results: Among the 639 respondents, the prevalence rate of internet gaming disorder was 2.03% (n=13), with a mean age of 20.23 (SD 0.13) years and an average gaming duration of 19.0 (SD 0.96) hours/week. Up to 71.2% respondents played using their mobile phones, and respondents with internet gaming disorder reported experiencing all psychopathologies assessed, except phobic anxiety. Bivariate analysis demonstrated that internet gaming disorder was associated with gender, gaming duration, gaming community affiliation, and 9 out of 10 domains of psychopathology. In a logistic regression model, internet gaming disorder was correlated with weekly gaming hours ≥20 hours (odds ratio [OR] 4.21, 95% CI 1.08-16.38, P=.04). Conclusions: These findings suggest that the prevalence of internet gaming disorder among medical students in Jakarta, Indonesia is similar to that in other populations of Asian countries. The predisposing factor for internet gaming disorder was weekly gaming duration, while other demographic, temperament, and psychopathology variables acted as probable moderators. Strategies should, therefore, be developed and integrated into medical curriculum to screen and aid individuals with these predisposing factors. © Kristiana Siste, Enjeline Hanafi, Lee Thung Sen, Petra Octavian Perdana Wahjoepramono, Ryan Yudistiro, Ryan Yudistiro. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 19.04.2021. This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on http://www.jmir.org/, as well as this copyright and license information must be included. |
Internet gaming disorder; Medical students; Psychopathology; Risk factors; Temperament |
adult; anxiety disorder; Article; comparative study; correlational study; cross-sectional study; demography; depression; disease association; female; game addiction; hostility; human; Indonesia; internet gaming disorder test; major clinical study; male; medical student; mental disease assessment; neuropathology; obsessive compulsive disorder; online game; paranoia; prevalence; questionnaire; sex difference; somatization; Symptom Checklist 90; temperament; temperament and character inventory; young adult; addiction; Internet; internet addiction; video game; Adult; Behavior, Addictive; Cross-Sectional Studies; Humans; Indonesia; Internet; Internet Addiction Disorder; Students, Medical; Video Games; Young Adult |
JMIR Publications Inc. |
14388871 |
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33871379 |
Article |
Q1 |
1446 |
2408 |
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466 |
Sen L.T., Hutauruk P.M.S., Putra M.R.A., Maulida S.B., Ramadhan A., Sugiharto A. |
57219034101;57222897908;57222899118;57222902406;57220357068;57204117635; |
Scrutinizing the knowledge and stigma of HIV/AIDS in the community level in Indonesia and the correlation to risk groups aversion to screening |
2021 |
IOP Conference Series: Earth and Environmental Science |
716 |
1 |
012089 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85104173128&doi=10.1088%2f1755-1315%2f716%2f1%2f012089&partnerID=40&md5=cd113c28d7b8389535c7d2bf89f521fd |
Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia |
Sen, L.T., Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Hutauruk, P.M.S., Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Putra, M.R.A., Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Maulida, S.B., Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Ramadhan, A., Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Sugiharto, A., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia |
Human immunodeficiency virus (HIV) has continuously been considered a scourge in Indonesia. Negative societal stance might be attributed to the poor biological, psychological, and emotional knowledge of HIV. Here we aimed to demonstrate the level of knowledge, stigma, and barriers for accessing HIV services. We conducted a cross-sectional survey in December 2019 in Kemayoran District, Jakarta, Indonesia. The survey consisted of a demographic section, HIV-Knowledge Questionnaire 18, and Stigma Questionnaires. An in-depth interview was conducted with eight subjects representing high-risk HIV and healthcare professionals; in-vivo and thematic analysis were employed. Overall, 83 respondents participated, 50.6% male, and 61.7% aged 26-45 years old. Instrumental, symbolic, and civility stigma were significantly higher in 25.9%, 19.8%, and 17.3% of samples, respectively. Stigma was associated with HIV knowledge (λ: 0.887, df: 3, partial η2: 0.113), and high knowledge level decreased the odds of instrumental stigma (OR: 0.292, 95% CI 0.095-0.900, p<0.05). Fear of discrimination and limited information was identified as intrinsic factors, while media portrays HIV and extraneous screening hours as extrinsic factors. The knowledge on HIV is still low at the community level in the Indonesian capital, which correlates to higher stigma and inhibits the high-risk population from accessing HIV medical services. © Published under licence by IOP Publishing Ltd. |
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Diagnosis; Planning; Risk assessment; Surveys; Sustainable development; Viruses; Cross-sectional surveys; Extrinsic factors; Health care professionals; Human immunodeficiency virus; In-depth interviews; Intrinsic factors; Limited information; Thematic analysis; Diseases |
IOP Publishing Ltd |
17551307 |
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Conference Paper |
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179 |
20770 |
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467 |
Miftahussurur M., Doohan D., Syam A.F., Nusi I.A., Subsomwong P., Waskito L.A., Maulahela H., Akil F., Uwan W.B., Siregar G., Fauzia K.A., Rezkitha Y.A.A., Rahman A., Wibawa I.D.N., Saudale A.M.J., Richardo M., Sugihartono T., Chomariyati A., Bramantoro T., Uchida T., Yamaoka Y. |
56323903000;57204644036;8443384400;56543515200;57113712700;57192177367;57189612709;35191671700;57093988500;56483277100;57204649404;56543533600;57212819255;6504449940;57192179505;57207621686;57194156387;57222871823;57196010143;35286123100;55183784100; |
Cyp2c19 polymorphisms in indonesia: Comparison among ethnicities and the association with clinical outcomes |
2021 |
Biology |
10 |
4 |
300 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85104101307&doi=10.3390%2fbiology10040300&partnerID=40&md5=5c1d7696c67d83bbcf546211d5004bf0 |
Gastroentero-Hepatology Division, Department of Internal Medicine, Faculty of Medicine-Dr, Soetomo Teaching Hospital, Universitas Airlangga, Surabaya, 60286, Indonesia; Institute of Tropical Disease, Universitas Airlangga, Surabaya, 60115, Indonesia; Department of Environmental and Preventive Medicine, Oita University, Faculty of Medicine, Yufu, 879-5593, Japan; Department of Microbiology and Immunology, Hirosaki University Graduate School of Medicine, Aomori, Hirosaki, 036-8562, Japan; Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, University of Indonesia, Jakarta, 10430, Indonesia; Center of Gastroentero-Hepatology, Department of Internal Medicine, Faculty of Medicine, Hasanuddin University, Makassar, 90245, Indonesia; Department of Internal Medicine, Santo Antonius Hospital, Pontianak, 78243, Indonesia; Division of Gastroentero-Hepatology, Department of Internal Medicine, Faculty of Medicine, University of Sumatra Utara, Medan, 20155, Indonesia; Faculty of Medicine, University of Muhammadiyah Surabaya, Surabaya, 60113, Indonesia; Department of Internal Medicine, Kolaka General Hospital, Kolaka, 93511, Indonesia; Division of Gastroentero-Hepatology, Department of Internal Medicine, Faculty of Medicine, University of Udayana, Denpasar, 80232, Indonesia; Department of Internal Medicine, Prof. Dr. W. Z. Johannes General Hospital, Kupang, 85111, Indonesia; Department of Internal Medicine, Merauke City General Hospital, Merauke, 99613, Indonesia; Department of Dental Public Health, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, 60131, Indonesia; Department of Molecular Pathology, Oita University, Faculty of Medicine, Yufu, 879-5593, Japan; Global Oita Medical Advanced Research Center for Health, Oita University, Yufu, 879-5593, Japan; Department of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, TX 77030, United States |
Miftahussurur, M., Gastroentero-Hepatology Division, Department of Internal Medicine, Faculty of Medicine-Dr, Soetomo Teaching Hospital, Universitas Airlangga, Surabaya, 60286, Indonesia, Institute of Tropical Disease, Universitas Airlangga, Surabaya, 60115, Indonesia; Doohan, D., Institute of Tropical Disease, Universitas Airlangga, Surabaya, 60115, Indonesia, Department of Environmental and Preventive Medicine, Oita University, Faculty of Medicine, Yufu, 879-5593, Japan; Syam, A.F., Department of Microbiology and Immunology, Hirosaki University Graduate School of Medicine, Aomori, Hirosaki, 036-8562, Japan; Nusi, I.A., Gastroentero-Hepatology Division, Department of Internal Medicine, Faculty of Medicine-Dr, Soetomo Teaching Hospital, Universitas Airlangga, Surabaya, 60286, Indonesia; Subsomwong, P., Department of Environmental and Preventive Medicine, Oita University, Faculty of Medicine, Yufu, 879-5593, Japan, Department of Microbiology and Immunology, Hirosaki University Graduate School of Medicine, Aomori, Hirosaki, 036-8562, Japan; Waskito, L.A., Institute of Tropical Disease, Universitas Airlangga, Surabaya, 60115, Indonesia, Department of Environmental and Preventive Medicine, Oita University, Faculty of Medicine, Yufu, 879-5593, Japan; Maulahela, H., Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, University of Indonesia, Jakarta, 10430, Indonesia; Akil, F., Center of Gastroentero-Hepatology, Department of Internal Medicine, Faculty of Medicine, Hasanuddin University, Makassar, 90245, Indonesia; Uwan, W.B., Department of Internal Medicine, Santo Antonius Hospital, Pontianak, 78243, Indonesia; Siregar, G., Division of Gastroentero-Hepatology, Department of Internal Medicine, Faculty of Medicine, University of Sumatra Utara, Medan, 20155, Indonesia; Fauzia, K.A., Institute of Tropical Disease, Universitas Airlangga, Surabaya, 60115, Indonesia, Department of Environmental and Preventive Medicine, Oita University, Faculty of Medicine, Yufu, 879-5593, Japan; Rezkitha, Y.A.A., Institute of Tropical Disease, Universitas Airlangga, Surabaya, 60115, Indonesia, Faculty of Medicine, University of Muhammadiyah Surabaya, Surabaya, 60113, Indonesia; Rahman, A., Department of Internal Medicine, Kolaka General Hospital, Kolaka, 93511, Indonesia; Wibawa, I.D.N., Division of Gastroentero-Hepatology, Department of Internal Medicine, Faculty of Medicine, University of Udayana, Denpasar, 80232, Indonesia; Saudale, A.M.J., Department of Internal Medicine, Prof. Dr. W. Z. Johannes General Hospital, Kupang, 85111, Indonesia; Richardo, M., Department of Internal Medicine, Merauke City General Hospital, Merauke, 99613, Indonesia; Sugihartono, T., Gastroentero-Hepatology Division, Department of Internal Medicine, Faculty of Medicine-Dr, Soetomo Teaching Hospital, Universitas Airlangga, Surabaya, 60286, Indonesia; Chomariyati, A., Gastroentero-Hepatology Division, Department of Internal Medicine, Faculty of Medicine-Dr, Soetomo Teaching Hospital, Universitas Airlangga, Surabaya, 60286, Indonesia; Bramantoro, T., Department of Dental Public Health, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, 60131, Indonesia; Uchida, T., Department of Molecular Pathology, Oita University, Faculty of Medicine, Yufu, 879-5593, Japan; Yamaoka, Y., Gastroentero-Hepatology Division, Department of Internal Medicine, Faculty of Medicine-Dr, Soetomo Teaching Hospital, Universitas Airlangga, Surabaya, 60286, Indonesia, Department of Environmental and Preventive Medicine, Oita University, Faculty of Medicine, Yufu, 879-5593, Japan, Global Oita Medical Advanced Research Center for Health, Oita University, Yufu, 879-5593, Japan, Department of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, TX 77030, United States |
CYP2C19 polymorphisms are important factors for proton pump inhibitor-based therapy. We examined the CYP2C19 genotypes and analyzed the distribution among ethnicities and clinical outcomes in Indonesia. We employed the polymerase chain reaction-restriction fragment length polymorphism method to determine the CYP2C19 genotypes and evaluated inflammation severity with the updated Sydney system. For CYP2C19*2, 46.4% were the homozygous wild-type allele, 14.5% were the homozygous mutated allele, and 39.2% were the heterozygous allele. For CYP2C19*3, 88.6% were the homozygous wild-type allele, 2.4% were the homozygous mutated allele, and 9.0% were the heterozygous allele. Overall, the prevalence of rapid, intermediate, and poor metabolizers in Indonesia was 38.5, 41.6, and 19.9%, respectively. In the poor metabolizer group, the frequency of allele *2 (78.8%) was higher than the frequency of allele *3 (21.2%). The Papuan had a significantly higher likelihood of possessing poor metabolizers than the Balinese (OR 11.0; P = 0.002). The prevalence of poor metabolizers was lower compared with the rapid and intermediate metabolizers among patients with gastritis and gastroesophageal reflux disease. Intermediate metabolizers had the highest prevalence, followed by rapid metabolizers and poor metabolizers. Dosage adjustment should therefore be considered when administering proton pump inhibitor-based therapy in Indonesia. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
CYP2C19; Gastritis; H. pylori; Infectious disease; Polymorphism |
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MDPI AG |
20797737 |
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Article |
Q1 |
1731 |
1747 |
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468 |
Prasetyo M., Moniqa R., Tulaar A., Prihartono J., Setiawan S.I. |
57192905252;57221866634;24330360800;6602605635;57195939543; |
Correlation between Hemophilia Early Arthropathy Detection with Ultrasound (HEAD-US) score and Hemophilia Joint Health Score (HJHS) in patients with hemophilic arthropathy |
2021 |
PLoS ONE |
16 |
4 April |
e0248952 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103995985&doi=10.1371%2fjournal.pone.0248952&partnerID=40&md5=33018f7adcb5c975c29264deba385db3 |
Department of Radiology, Faculty of Medicine Universitas Indonesia-Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Department of Medical Rehabilitation, Faculty of Medicine Universitas Indonesia-Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Department of Community Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Prasetyo, M., Department of Radiology, Faculty of Medicine Universitas Indonesia-Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Moniqa, R., Department of Radiology, Faculty of Medicine Universitas Indonesia-Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Tulaar, A., Department of Medical Rehabilitation, Faculty of Medicine Universitas Indonesia-Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia; Prihartono, J., Department of Community Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Setiawan, S.I., Department of Radiology, Faculty of Medicine Universitas Indonesia-Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia |
Background Hemophilic arthropathy, a condition manifested as joint destruction due to spontaneous joint bleeding, is one complication of hemophiliac patients. Early detection and intervention may improve the outcome, in which ultrasonography can be an ideal modality with the introduction of HEAD-US (Hemophilia Early Arthropathy Detection with Ultrasound) protocol. Studies have shown US benefit in hemophiliac patients, including its potential as an alternative for the Hemophiliac Joint Health Score (HJHS) system. However, many of the studies were conducted in countries with better management of hemophilia using prophylaxis treatment. It is unclear whether HEAD-US has a correlation with HJHS in countries using episodic treatment only, like in Indonesia. Purpose This study aimed to explore the correlation between HEAD-US and HJHS in hemophiliac patients with joint problems in Indonesia. Materials and methods A cross-sectional correlation study between HEAD-US and HJHS was performed with primary data collected from 120 hemophilic patients. US examination was performed on elbow, knee and ankle joints using the HEAD-US scoring method by a musculoskeletal radiologist. HJHS examination was conducted by a trained physiotherapist and a medical rehabilitation specialist. All examiner is member of multidisciplinary Hemophiliac Management Team in Cipto Mangunkusumo General Hospital in Jakarta, Indonesia. Results The mean age of the participant was 9.3 (5-14) years old. The median score of HEAD-US was 8 (1-28) with most of the joint abnormalities found on the ankles. The median score of HJHS was 3 (0-35), with most joint abnormalities found on the knees. There was a moderate correlation between HEAD-US and HJHS score (p < 0.05, r = 0.65). Conclusion HEAD-US shows a moderate correlation to HJHS in hemophiliac patients who received episodic treatment. HEAD-US can provide additional value in the anatomical evaluation of the joint and could be complementary to HJHS in assessing the joint status in hemophilic patient. © 2021 Prasetyo et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
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adolescent; ankle; Article; child; controlled study; correlational study; cross-sectional study; disease assessment; echography; elbow; Hemophilia Early Arthropathy Detection with Ultrasound score; Hemophilia Joint Health Score; hemophilic arthropathy; human; Indonesia; information processing; knee; major clinical study; medical specialist; musculoskeletal radiologist; physiotherapist; scoring system; arthropathy; diagnostic imaging; early diagnosis; echography; hemophilia A; joint; pathology; preschool child; procedures; Adolescent; Child; Child, Preschool; Cross-Sectional Studies; Early Diagnosis; Hemophilia A; Humans; Indonesia; Joint Diseases; Joints; Ultrasonography |
Public Library of Science |
19326203 |
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33826621 |
Article |
Q1 |
990 |
4434 |
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469 |
Surendra H., Elyazar I.R., Djaafara B.A., Ekawati L.L., Saraswati K., Adrian V., Widyastuti, Oktavia D., Salama N., Lina R.N., Andrianto A., Lestari K.D., Burhan E., Shankar A.H., Thwaites G., Baird J.K., Hamers R.L. |
57192694199;6506894785;57211600737;55600338600;57201491297;57221369753;57221446622;57219415909;57219411020;57221371068;57221369803;57221368778;36058554600;7005442634;6603796838;15921267800;23034345900; |
Clinical characteristics and mortality associated with COVID-19 in Jakarta, Indonesia: A hospital-based retrospective cohort study |
2021 |
The Lancet Regional Health - Western Pacific |
9 |
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100108 |
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11 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103798622&doi=10.1016%2fj.lanwpc.2021.100108&partnerID=40&md5=5627a271c3a8af3583dd02d7d63fadab |
Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia; Centre for Tropical Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia; Akademi Ilmuwan Muda Indonesia, Jakarta, Indonesia; MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Jakarta Provincial Health Office, Jakarta, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Viet Nam |
Surendra, H., Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia, Centre for Tropical Medicine, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia, Akademi Ilmuwan Muda Indonesia, Jakarta, Indonesia; Elyazar, I.R., Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia, Akademi Ilmuwan Muda Indonesia, Jakarta, Indonesia; Djaafara, B.A., Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia, MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom; Ekawati, L.L., Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Saraswati, K., Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Adrian, V., Jakarta Provincial Health Office, Jakarta, Indonesia; Widyastuti, Jakarta Provincial Health Office, Jakarta, Indonesia; Oktavia, D., Jakarta Provincial Health Office, Jakarta, Indonesia; Salama, N., Jakarta Provincial Health Office, Jakarta, Indonesia; Lina, R.N., Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia; Andrianto, A., Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia; Lestari, K.D., Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia; Burhan, E., Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Shankar, A.H., Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Thwaites, G., Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom, Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Viet Nam; Baird, J.K., Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom; Hamers, R.L., Eijkman-Oxford Clinical Research Unit, Jakarta, Indonesia, Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Background: Data on COVID-19-related mortality and associated factors from low-resource settings are scarce. This study examined clinical characteristics and factors associated with in-hospital mortality of COVID-19 patients in Jakarta, Indonesia, from March 2 to July 31, 2020. Methods: This retrospective cohort included all hospitalised patients with PCR-confirmed COVID-19 in 55 hospitals. We extracted demographic and clinical data, including hospital outcomes (discharge or death). We used logistic regression to examine factors associated with mortality. Findings: Of 4265 patients with a definitive outcome by July 31, 3768 (88%) were discharged and 497 (12%) died. The median age was 46 years (IQR 32–57), 5% were children, and 31% had >1 comorbidity. Age-specific mortalities were 11% (7/61) for <5 years; 4% (1/23) for 5–9; 2% (3/133) for 10–19; 2% (8/638) for 20–29; 3% (26/755) for 30–39; 7% (61/819) for 40–49; 17% (155/941) for 50–59; 22% (132/611) for 60–69; and 34% (96/284) for ≥70. Risk of death was associated with higher age, male sex; pre-existing hypertension, diabetes, or chronic kidney disease; clinical diagnosis of pneumonia; multiple (>3) symptoms; immediate ICU admission, or intubation. Across all ages, risk of death was higher for patients with >1 comorbidity compared to those without; notably the risk was six-fold increased among patients <50 years (adjusted odds ratio 5.87, 95%CI 3.28–10.52; 27% vs 3% mortality). Interpretation: Overall in-hospital mortality was lower than reported in high-income countries, probably due to younger age distribution and fewer comorbidities. Deaths occurred across all ages, with >10% mortality among children <5 years and adults >50 years. © 2021 |
children; coronavirus; COVID-19; Indonesia; Mortality; SARS-CoV-2 |
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Elsevier Ltd |
26666065 |
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Article |
#N/A |
#N/A |
#N/A |
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470 |
Takhwifa F., Aninditha T., Setiawan H., Sauriasari R. |
57222711645;57189611205;55292870100;16246507200; |
The potential of metformin as an antineoplastic in brain tumors: A systematic review |
2021 |
Heliyon |
7 |
4 |
e06558 |
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3 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103788211&doi=10.1016%2fj.heliyon.2021.e06558&partnerID=40&md5=ec9287d374f7d13b7c0752898249a4ba |
Faculty of Pharmacy, Universitas Indonesia, Depok, West Java 16424, Indonesia; Department of Neurology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Takhwifa, F., Faculty of Pharmacy, Universitas Indonesia, Depok, West Java 16424, Indonesia; Aninditha, T., Department of Neurology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Setiawan, H., Faculty of Pharmacy, Universitas Indonesia, Depok, West Java 16424, Indonesia; Sauriasari, R., Faculty of Pharmacy, Universitas Indonesia, Depok, West Java 16424, Indonesia |
Brain tumors are challenging to handle and cause severe mortality and morbidity. The primary therapy for brain tumors, a combination of radiotherapy, chemotherapy (i.e temozolomide), and corticosteroids, is considered inadequate to improve patients' clinical conditions and associated with many adverse effects. There is an urgent need for new compounds or repurposing of existing therapies, which could improve brain tumor patients' prognosis. Metformin, commonly used for type 2 diabetes medication, has been examined for its protective action in cancer, reducing cancer risk and cancer-related mortality. However, its effect on cancer is still in rigorous debate. This study examines recent studies on the effects of metformin in primary brain tumor patients through systematic reviews. The literature search was performed on PubMed, ScienceDirect, and SpringerLink databases for articles published between 2013 and 2020. We selected clinical studies comparing the therapeutic outcomes of brain tumor therapy with and without metformin. The clinical benefits of the drug were assessed through the overall survival (OS) and progression-free survival (PFS) of brain tumor patients. Those studies demonstrated that the combination of metformin with temozolomide given post-radiotherapy resulted in better OS and PFS. Nonetheless, the efficacy and safety of metformin need further clinical testing in the wider population. © 2021 The Authors |
Antidiabetic; Antineoplastic; Metformin; Primary brain tumor; Survival |
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Elsevier Ltd |
24058440 |
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Review |
Q1 |
455 |
10919 |
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471 |
Sampurna M.T.A., Rohsiswatmo R., Primadi A., Wandita S., Sulistijono E., Bos A.F., Sauer P.J.J., Hulzebos C.V., Dijk P.H. |
57201733407;55533574600;8422152900;57194904658;57218101844;36839156800;57191375642;6603928053;6701798049; |
The knowledge of Indonesian pediatric residents on hyperbilirubinemia management |
2021 |
Heliyon |
7 |
4 |
e06661 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103706107&doi=10.1016%2fj.heliyon.2021.e06661&partnerID=40&md5=fe30c346677666133417d4195cc4b825 |
Neonatology Division, Department of Pediatrics, Airlangga University Teaching Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Neonatology Division, Department of Pediatrics, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Department of Pediatrics, Hasan Sadikin Hospital, Faculty of Medicine, Universitas Padjajaran, Bandung, Indonesia; Neonatology Division, Department of Child Health, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia; Department of Pediatrics, Saiful Anwar Hospital, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia; Department of Pediatrics, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, Netherlands |
Sampurna, M.T.A., Neonatology Division, Department of Pediatrics, Airlangga University Teaching Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Rohsiswatmo, R., Neonatology Division, Department of Pediatrics, Cipto Mangunkusumo Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Primadi, A., Department of Pediatrics, Hasan Sadikin Hospital, Faculty of Medicine, Universitas Padjajaran, Bandung, Indonesia; Wandita, S., Neonatology Division, Department of Child Health, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia; Sulistijono, E., Department of Pediatrics, Saiful Anwar Hospital, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia; Bos, A.F., Department of Pediatrics, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, Netherlands; Sauer, P.J.J., Department of Pediatrics, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, Netherlands; Hulzebos, C.V., Department of Pediatrics, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, Netherlands; Dijk, P.H., Department of Pediatrics, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, Netherlands |
Hyperbilirubinemia in the newborn occurs more frequently in Indonesia. Therefore, it is important that pediatric residents in Indonesia acquire adequate knowledge of hyperbilirubinemia management. This study aims to determine the pediatric residents' knowledge on hyperbilirubinemia management, whether they follow recommended guidelines, and whether differences exist between five large Indonesian teaching hospitals. We handed out a 25-question questionnaire on hyperbilirubinemia management to pediatric residents at five teaching hospitals. A total of 250 questionnaires were filled in completely, ranging from 14 to 113 respondents per hospital. Approximately 76% of the respondents used the Kramer score to recognize neonatal jaundice. Twenty-four percent correctly plotted the total serum bilirubin levels (TSB) on the phototherapy (PT) nomograms provided by the American Academy of Pediatrics (AAP) and the National Institute for Health and Care Excellence (NICE) for full-term and nearly full-term infants. Regarding preterm infants <35 weeks' gestational age, 66% of the respondents plotted TSB levels on the AAP nomogram, although this nomogram doesn't apply to this category of infants. Seventy percent of residents knew when to perform an exchange transfusion whereas 27% used a fixed bilirubin cut-off value of 20 mg/dL. Besides PT, 25% reported using additional pharmaceutical treatments, included albumin, phenobarbitone, ursodeoxycholic acid and immunoglobulins, while 47% of the respondents used sunlight therapy, as alternative treatment. The limited knowledge of the pediatric residents could be one factor for the higher incidence of severe hyperbilirubinemia and its sequelae. The limited knowledge of the residents raises doubts about the knowledge of the supervisors and the training of the residents since pediatric residents receive training from their supervisors. © 2021 The Author(s) |
Guidelines; Hyperbilirubinemia; Knowledge; Newborn infants; Residents |
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Elsevier Ltd |
24058440 |
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Article |
Q1 |
455 |
10919 |
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