No records
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476 |
Kamal A.F., Abubakar I., Salamah T. |
56648996700;57204179162;57195380322; |
Alkaline phosphatase, lactic dehidrogenase, inflammatory variables and apparent diffusion coefficients from MRI for prediction of chemotherapy response in osteosarcoma. A cross sectional study |
2021 |
Annals of Medicine and Surgery |
64 |
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102228 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102644624&doi=10.1016%2fj.amsu.2021.102228&partnerID=40&md5=fd665964a20c5345b17f1145f1383619 |
Department of Orthopaedic and Traumatology Faculty of Medicine Universitas Indonesia/ Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Division of Orthopaedic and Traumatology-Department of Surgery Faculty of Medicine Universitas Syiah Kuala/ Zainoel Abidin General Hospital, Banda Aceh, Indonesia; Department of Radiology Faculty of Medicine Universitas Indonesia/Cipto Mangunkusumo, General Hospital, Jakarta, Indonesia |
Kamal, A.F., Department of Orthopaedic and Traumatology Faculty of Medicine Universitas Indonesia/ Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Abubakar, I., Department of Orthopaedic and Traumatology Faculty of Medicine Universitas Indonesia/ Cipto Mangunkusumo General Hospital, Jakarta, Indonesia, Division of Orthopaedic and Traumatology-Department of Surgery Faculty of Medicine Universitas Syiah Kuala/ Zainoel Abidin General Hospital, Banda Aceh, Indonesia; Salamah, T., Department of Radiology Faculty of Medicine Universitas Indonesia/Cipto Mangunkusumo, General Hospital, Jakarta, Indonesia |
Background: This present study aimed to assess if clinical, laboratory and MRI were an accurate benchmark in assessing the effectiveness of neoadjuvant chemotherapy in osteosarcoma patients. Methods: This was an observational analytic study with a cross-sectional design. We correlated among clinical, laboratory and magnetic resonance imaging (MRI) data before and after neoadjuvant chemotherapy; and percentage of tumor necroses from osteosarcoma patients during the period between January 2017–July 2019. Results: Of the 58 patients included in this study, 38 were male and 20 were female aged 5 - 67 years (mean: 16-year-old. 37(63.8%) patients underwent neoadjuvant chemotherapy with CAI regimens and 13 (36.2%) with CA regiments. The tumors were classified as stage IIB in 43 (74.1%) patients and stage III in 15 (25.9%) patients. Wilcoxon test showed significant differences between alkaline phosphatase (ALP), erythrocyte sedimentation rate (ESR), and neutrophil to lymphocyte ratio (NLR) before and after neoadjuvant chemotherapy in the poor-response group. We found no significant difference between lactic dehydrogenase (LDH) and lymphocyte-to-monocyte ratio (LMR) before and after neoadjuvant chemotherapy in the good-response group. MRI revealed decreased tumor volume in patients in the good-response to chemotherapy. Conclusion: We demonstrated that ALP level was statistically significant in the poor-response group. We also found that LDH value before neoadjuvant chemotherapy had a strong correlation with degree of necrosis and could be used as a predictive indicator. MRI plays an important role in evaluating tumor volumes and preoperative radiological changes to predict histological necrosis. © 2021 |
Alkaline phospkatase; Chemotherapy; LDH; MRI Apparent diffusion coefficients; NLR,LMR; Osteosarcoma |
alanine aminotransferase; alkaline phosphatase; C reactive protein; cisplatin; doxorubicin; fluorodeoxyglucose f 18; ifosfamide; lactate dehydrogenase; adjuvant therapy; adolescent; adult; aged; analytical research; apparent diffusion coefficient; Article; cancer chemotherapy; cancer size; cancer staging; child; comparative effectiveness; computer assisted tomography; cross-sectional study; erythrocyte sedimentation rate; female; histology; human; human tissue; hypertransaminasemia; lymphocyte monocyte ratio; major clinical study; male; MSTS score; neoadjuvant chemotherapy; neutrophil lymphocyte ratio; nuclear magnetic resonance imaging; observational study; osteosarcoma; platelet lymphocyte ratio; receiver operating characteristic; retrospective study; scoring system; treatment response; |
Elsevier Ltd |
20490801 |
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Article |
Q3 |
391 |
12334 |
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477 |
Surachman A.J.D., Yanuarso, Akbar D.L. |
57222404106;57222408215;57219271823; |
Emergency decompression and stabilization of 1st thoracic spinal cord injury and sacral fracture in a Covid-19 patient: A case report |
2021 |
International Journal of Surgery Case Reports |
81 |
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105670 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102643865&doi=10.1016%2fj.ijscr.2021.105670&partnerID=40&md5=fc2cec315c580c625636dffb12bb6883 |
Orthopaedics and Traumatology Department, Indonesia Army Central Hospital, Jakarta, Indonesia; Resident of Orthopaedics and Traumatology Department, Dr. Cipto Mangunkusumo National Central General Hospital/ Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Surachman, A.J.D., Orthopaedics and Traumatology Department, Indonesia Army Central Hospital, Jakarta, Indonesia; Yanuarso, Orthopaedics and Traumatology Department, Indonesia Army Central Hospital, Jakarta, Indonesia; Akbar, D.L., Resident of Orthopaedics and Traumatology Department, Dr. Cipto Mangunkusumo National Central General Hospital/ Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Introduction and importance: Spinal cord injury is mostly caused by traumatic accident and usually associated with several injuries. The ideal treatment of orthopaedic injury is to perform surgical decompression and stabilization early. Case presentation: A 24-year-old-male patient came in emergency department with history of severe pain in his thoracic vertebrae after fell from 10 m height. His buttock was hit the ground first and patient was alert. He felt hypoesthesia below the injured level and dysfunctional motor and sensory of both lower extremities. We put pedicle screw at the C7, Th1, Th2 and Th 3. Then we put rods and nuts. After that, we did decompression by laminectomy of the C7 and Th1 and we put vacuumed drain for the wound. Clinical discussion: This patient was diagnosed with traumatic spinal cord injury of 1st thoracic vertebra ASIA Impairment Scale (AIS) C and sacral fracture Denis classification zone II of right side with confirmed Covid-19 case. First patient treated with 1000 mg methyl prednisolone. An early surgical treatment was open reduction and internal fixation (ORIF) sacral fracture. We put a two-hole 4.5 narrow dynamic compression plate (DCP) at the lateral side of posterior ridge of iliac bone, between posterior superior iliac spine (PSIS) and posterior inferior iliac spine (PIIS). Conclusion: Immediate surgical decompression and stabilization for spinal cord injury give significant improvement in motor and sensory function. Appropriate management for Covid-19 patient with Favipiravir and some supplements, had been proved control the virus and give patient good quality of life. © 2021 |
Covid-19; Sacral fracture; Spinal cord injury |
D dimer; favipiravir; methylprednisolone; adult; antiviral therapy; Article; bleeding prophylaxis; bolus injection; buttock; case report; clinical article; compression fracture; coronavirus disease 2019; corticosteroid therapy; COVID-19 nucleic acid testing; disease severity; drug dose reduction; early intervention; emergency surgery; emergency ward; enhanced recovery after surgery; erythrocyte concentrate; falling; general condition improvement; human; hypesthesia; iliac bone; intensive care unit; laminectomy; limb dysesthesia; limb weakness; lower limb; male; medical history; motor dysfunction; muscle strength; nasopharyngeal swab; nuclear magnetic resonance imaging; open fracture reduction; operative blood loss; osteosynthesis; palpation; pelvic pain; pelvis radiography; physical examin |
Elsevier Ltd |
22102612 |
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Article |
Q3 |
232 |
17549 |
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478 |
Harzif A.K., Ambalagen S., Charilda F.E., Mutia H.D. |
57191493435;57222325337;57222329284;57214329625; |
A rare case of multiple leiomyomas on rudimentary uterus in a woman with Mayer Rokitansky Kuster Hauser (MRKH) syndrome: A challenging diagnosis and laparoscopic approach |
2021 |
International Journal of Surgery Case Reports |
81 |
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105711 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102294473&doi=10.1016%2fj.ijscr.2021.105711&partnerID=40&md5=bba041a44dbdde737dce08836c3493cf |
Division of Reproductive Immuno-Endocrinology, Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital Jakarta, Indonesia; Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo Hospital Jakarta, Faculty of Medicine Universitas Indonesia, Pangeran Diponegoro Street No. 71, Kenari, Jakarta, Indonesia; Indonesian Reproductive Medicine Research and Training Center (INA- REPROMED), Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital Jakarta, Pangeran Diponegoro Street No. 71, Kenari, Central of Jakarta, 10430, Indonesia |
Harzif, A.K., Division of Reproductive Immuno-Endocrinology, Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital Jakarta, Indonesia; Ambalagen, S., Department of Obstetrics and Gynecology, Dr. Cipto Mangunkusumo Hospital Jakarta, Faculty of Medicine Universitas Indonesia, Pangeran Diponegoro Street No. 71, Kenari, Jakarta, Indonesia; Charilda, F.E., Indonesian Reproductive Medicine Research and Training Center (INA- REPROMED), Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital Jakarta, Pangeran Diponegoro Street No. 71, Kenari, Central of Jakarta, 10430, Indonesia; Mutia, H.D., Indonesian Reproductive Medicine Research and Training Center (INA- REPROMED), Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital Jakarta, Pangeran Diponegoro Street No. 71, Kenari, Central of Jakarta, 10430, Indonesia |
Mayer Rokitansky Kuster Hauser (MRKH) syndrome is a congenital disorder involving reproductive, genitourinary, bone, and cardiac malformation. The incidence is 1 in 4000–5000 females livebirths. The phenotype is female 46 XX karyotype, normal secondary sexual characteristics, and normal functional ovaries. The occurrence of leiomyoma in uterine remnant in MRKH syndrome is a very rare case, even though several cases have been reported. The diagnosis and management approach, in this case, is quite challenging. Here, we report a 38 years old female who represents multiple leiomyomas on the rudimentary uterus, then we did laparoscopic removal of the fibroids and adjacent rudimentary uterus. © 2021 |
Case report; Laparascopic; Mayer Rokitansky Kuster Hauser (MRKH) syndrome; Multiple leiomyomas; Rudimentary uterus |
analgesic agent; abdominal discomfort; abdominal pain; adult; analgesia; Article; clinical assessment; echography; family history; female; genital system; hair; histopathology; human; infertility; karyotype 46,XX; laparoscopic surgery; leiomyoma; major clinical study; multiple cancer; nuclear magnetic resonance imaging; ovary function; pelvic examination; physical examination; primary amenorrhea; priority journal; Rokitansky syndrome; secondary sexual characteristics; sexual intercourse; transabdominal ultrasonography; transrectal ultrasonography; uterus horn; uterus myoma; vagina mucosa |
Elsevier Ltd |
22102612 |
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Article |
Q3 |
232 |
17549 |
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479 |
Indrawan D.H., Sigumonrong Y. |
57222327477;57209291346; |
Case report: The theory of post-ileocystoplasty spherical configuration in patients with low-capacity bladder |
2021 |
International Journal of Surgery Case Reports |
81 |
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105731 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102278318&doi=10.1016%2fj.ijscr.2021.105731&partnerID=40&md5=6af280fe10f677e5711beb7bae89a0f0 |
Department of Urology, Faculty of Medicine, Universitas Indonesia – Haji Adam Malik General Hospital Medan, Jl. Bunga Lau No.17, Kemenangan Tani, Kec. Medan Tuntungan, Kota Medan, Sumatera Utara, 20136, Indonesia; Division of Urology, Department of Surgery, Faculty of Medicine, Universitas Sumatera Utara – Haji Adam Malik General Hospital Medan, Jl. Bunga Lau No.17, Kemenangan Tani, Kec. Medan Tuntungan, Kota Medan, Sumatera Utara, 20136, Indonesia |
Indrawan, D.H., Department of Urology, Faculty of Medicine, Universitas Indonesia – Haji Adam Malik General Hospital Medan, Jl. Bunga Lau No.17, Kemenangan Tani, Kec. Medan Tuntungan, Kota Medan, Sumatera Utara, 20136, Indonesia; Sigumonrong, Y., Division of Urology, Department of Surgery, Faculty of Medicine, Universitas Sumatera Utara – Haji Adam Malik General Hospital Medan, Jl. Bunga Lau No.17, Kemenangan Tani, Kec. Medan Tuntungan, Kota Medan, Sumatera Utara, 20136, Indonesia |
Introduction: Bladder augmentation can be performed by detubularization of the small or large intestine. A large capacity bladder is necessary to avoid frequent urination; thus, the ileal sac must be able to store the maximum volume of urine with relatively low pressure and the shortest length of the intestine. The acceptable pressure capacity should always be under ureteric pressure to avoid back pressure and kidney damage. Large capacity at low pressure is referred to as good compliance. Desirable preparations for augmentation, which is the use of the shortest length of the intestine, reduce the chance of diarrhea and vitamin deficiency and retain the intestines which may be required for augmentation. Aim: Clinical and urodynamic evaluation of the recent postoperative condition of the patient who underwent ileocystoplasty, confirmed by the theory of detubularization (spherical) configuration. Case presentation: Patient with complaints of frequent urination and small amount of urine. Ultrasound examination showed low volume bladder capacity and bilateral hydronephrosis and hydroureter. From cystography and VCUG examination, low capacity bladder, grade 1 VUR on the right side, grade 4 VUR on the left side accompanied by bilateral hydronephrosis and hydroureter. The patient has a history of right nephrectomy in 2014 for pyonephrosis due to kidney stones. The patient was then subjected to bladder augmentation using a segment of the ileum (ileocystoplasty) in 2015. In the postoperative evaluation, clinical symptoms, radiological and uroflowmetric examinations were evaluated. Conclusion: The detubularization form offers greater volume and lower pressure in the reservoir to augment the bladder. © 2021 The Authors |
Bladder augmentation; Case report; Detubularization; Ileocystoplasty |
adolescent; Article; bladder augmentation; bladder capacity; bladder reconstruction; case report; clinical article; clinical assessment; cystography; cystostomy; diarrhea; end to end anastomosis; human; hydronephrosis; hydroureter; ileocystoplasty; ileum; intravenous pyelography; male; micturition cystourethrography; micturition disorder; nephrectomy; nephrolithiasis; nephrostomy; pollakisuria; polyuria; priority journal; pyonephrosis; surgical technique; treatment outcome; ultrasound; urine flow rate; uroflowmetry; vesicoureteral reflux; vitamin deficiency |
Elsevier Ltd |
22102612 |
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Article |
Q3 |
232 |
17549 |
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480 |
Sukmawan R., Hoetama E., Suridanda Danny S., Giantini A., Listiyaningsih E., Gilang Rejeki V., Aziz Alkatiri A., Firdaus I. |
8651025300;57214138849;57222312102;12776781400;57224237184;57222313503;57222311692;55796864700; |
Increase in the risk of clopidogrel resistance and consequent TIMI flow impairment by DNA hypomethylation of CYP2C19 gene in STEMI patients undergoing primary percutaneous coronary intervention (PPCI) |
2021 |
Pharmacology Research and Perspectives |
9 |
2 |
e00738 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85102225470&doi=10.1002%2fprp2.738&partnerID=40&md5=444f8c3e75e75ed786eedbe412614a0b |
Cardiology and Vascular Medicine Department, Faculty of Medicine Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Clinical Pathology Department, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo National Public Hospital, Jakarta, Indonesia; Indonesian Cardiovascular Research Center, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia |
Sukmawan, R., Cardiology and Vascular Medicine Department, Faculty of Medicine Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Hoetama, E., Cardiology and Vascular Medicine Department, Faculty of Medicine Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Suridanda Danny, S., Cardiology and Vascular Medicine Department, Faculty of Medicine Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Giantini, A., Clinical Pathology Department, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo National Public Hospital, Jakarta, Indonesia; Listiyaningsih, E., Indonesian Cardiovascular Research Center, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Gilang Rejeki, V., Cardiology and Vascular Medicine Department, Faculty of Medicine Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Aziz Alkatiri, A., Cardiology and Vascular Medicine Department, Faculty of Medicine Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia; Firdaus, I., Cardiology and Vascular Medicine Department, Faculty of Medicine Universitas Indonesia, National Cardiovascular Center Harapan Kita, Jakarta, Indonesia |
Clopidogrel resistance is an important risk factor of ischemic event recurrence after optimal antiplatelet therapy. This study aims to investigate the role of CYP2C19 gene DNA methylation as one of the epigenetic factors for the risk of clopidogrel resistance in STEMI patients undergoing PPCI. ST-segment elevation myocardial infarction (STEMI) patients undergoing PPCI were pretreated with clopidogrel, and their platelet function was measured using VerifyNow™ assay. The criteria for high on-treatment platelet reactivity (HPR) were defined according to the expert consensus criteria (PRU >208). DNA methylation of the CYP2C19 gene was performed using bisulfite genomic sequencing technology. Furthermore, clinical, laboratory, and angiographic data including TIMI flow were collected. Among 122 patients, clopidogrel resistance was found in 22%. DNA methylation level percentage was lower in the clopidogrel resistance group (76.7 vs. 88.8, p-value.038). But, the <50% methylation group was associated with increased risk of clopidogrel resistance (OR =4.5, 95%CI =2.1–9.3, p-value =.018). This group was also found to have suboptimal post-PCI TIMI flow (OR =3.4 95%CI =1.3–8.7, p-value =.045). The lower DNA methylation level of the CYP2C19 gene increases the risk of clopidogrel resistance and subsequent poorer clinical outcome. © 2021 The Authors. Pharmacology Research & Perspectives published by British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics and John Wiley & Sons Ltd. |
acute coronary syndrome; clopidogrel resistance; CYP2C19; DNA methylation |
acetylsalicylic acid; clopidogrel; cytochrome P450 2C19; clopidogrel; CYP2C19 protein, human; cytochrome P450 2C19; aged; angiography; blood clotting parameters; Cytochrome P450 2C19 gene; diabetes mellitus; DNA methylation; echocardiography; female; human; loading drug dose; major clinical study; male; percutaneous coronary intervention; Review; ST segment elevation myocardial infarction; adult; complication; drug effect; drug resistance; fibrinolytic therapy; genetics; metabolism; middle aged; percutaneous coronary intervention; procedures; recurrent disease; secondary prevention; ST segment elevation myocardial infarction; thrombocyte aggregation; Adult; Clopidogrel; Cytochrome P-450 CYP2C19; DNA Methylation; Drug Resistance; Female; Humans; Male; Middle Aged; Percutaneous Coronary Inte |
John Wiley and Sons Inc |
20521707 |
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33641235 |
Review |
Q1 |
975 |
4541 |
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481 |
Deviandri R., Siswanto I.G.M.F., Lubis A.M.T. |
57222171014;57222162272;15122639800; |
Mini open triple tunnel- double flip button techniques in treatment of acute acromioclavicular joint injuries: Case report |
2021 |
Trauma Case Reports |
32 |
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100450 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101784406&doi=10.1016%2fj.tcr.2021.100450&partnerID=40&md5=a224e173340aa2318470dfbe298e79a1 |
Department of Orthopedics, University of Groningen, University Medical Center Groningen, Groningen, Netherlands; Department of Physiology, Faculty of Medicine, Universitas Riau, Arifin Achmad Hospital, Pekanbaru, Indonesia; Department of Orthopedics Sport Injury, Royal Progress Hospital Jakarta, Indonesia; Department of Orthopedics, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Deviandri, R., Department of Orthopedics, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, Department of Physiology, Faculty of Medicine, Universitas Riau, Arifin Achmad Hospital, Pekanbaru, Indonesia; Siswanto, I.G.M.F., Department of Orthopedics Sport Injury, Royal Progress Hospital Jakarta, Indonesia; Lubis, A.M.T., Department of Orthopedics, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Acute acromioclavicular (AC) joint injuries are common and often occur in a contact sport activity. Most acute AC joint injuries surgery techniques focus on coracoclavicular (CC) ligament complex fixation; by single or double clavicle tunnel, but persisting vertical instability. In this paper, we introduce mini open triple tunnel- double flip button (TTDB) technique for acute AC joint dislocation by adding tunnel on clavicle to expand coverage of footprint of conoid and trapezoid ligament in order to improve vertical stability of the AC joint. This method is based on CC ligament augmentation with a double flip button/polydioxanone (PDS), combined with V-loop pulley suture for anatomical fixation. This is a prospective case report. Two professional, male basketball players in this study with a mean age of 25 years underwent surgery in 2019. Clinical subjective outcome, VAS score, Nottingham Clavicle Score, and radiological CC distance were measured before and after the operation. There were noticeable improvement in the patients' recovery after two years since the operation. We introduce TTDB technique as one of the open techniques for acute AC joint injuries in limited-resource hospital setting. © 2021 The Author(s) |
AC joint injuries; Double button; Triple tunnel; TTDB; V-loop suture |
acromioclavicular dislocation; adult; Article; basketball player; case report; clinical article; clinical outcome; human; male; Nottingham clavicle score; orthopedic surgery; prospective study; scoring system; sport injury; surgical technique; triple tunnel double flip button; visual analog scale |
Elsevier Ltd |
23526440 |
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Article |
Q3 |
183 |
20512 |
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482 |
Siste K., Wiguna T., Bardasono S., Sekartini R., Pandelaki J., Sarasvita R., Suwartono C., Murtani B.J., Damayanti R., Christian H., Sen L.T., Nasrun M.W. |
55644113100;24367785700;57222151719;57224503576;35759266900;50462352200;15078359800;57216652176;57215770702;57209266195;57219034101;57196216137; |
Internet addiction in adolescents: Development and validation of Internet Addiction Diagnostic Questionnaire (KDAI) |
2021 |
Psychiatry Research |
298 |
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113829 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101721252&doi=10.1016%2fj.psychres.2021.113829&partnerID=40&md5=57d16e1d74c98eda3345bc1ba9eca18e |
Department of Psychiatry, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Department of Nutrition, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Department of Child Health, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Department of Radiology, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Indonesia National Narcotics Board, Jakarta, Indonesia; Department of Psychology, Soegijapranata Catholic University, Semarang, Central Java, Indonesia; Faculty of Psychology, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia |
Siste, K., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Wiguna, T., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Bardasono, S., Department of Nutrition, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Sekartini, R., Department of Child Health, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Pandelaki, J., Department of Radiology, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Sarasvita, R., Indonesia National Narcotics Board, Jakarta, Indonesia, Department of Psychology, Soegijapranata Catholic University, Semarang, Central Java, Indonesia; Suwartono, C., Faculty of Psychology, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia; Murtani, B.J., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Damayanti, R., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Christian, H., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Sen, L.T., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Nasrun, M.W., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia- dr. Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Internet addiction (IA) is an emerging behavioral problem that constitutes a major health threat to vulnerable populations, including adolescents. However, there is a paucity of IA screening tools specifically designed for adolescents, especially in Indonesia. Therefore, the current study developed and validated the IA Diagnostic Questionnaire (KDAI) in adolescents while acknowledging local cultural influences. The KDAI was conceived through extensive literature reviews, expert discussions based on Delphi methods, a face validity study, focus group discussion (N = 31) for initial reliability testing, and a recruited pilot study (N = 385) and main study (N = 643) for exploratory and confirmatory factor analyses, respectively. The multi-sample analyses demonstrated that the KDAI model with the best fit and reliability comprised a seven-factor structure, including withdrawal, loss of control, increase of priority, negative consequences, mood modification, salience, and impairment. These factors were scrutinized against domains of IA Test, and concurrent validity was ascertained. Subsequently, a receiver operating characteristic curve and area under the curve determined a cutoff score of 108 to discern adolescents with IA. Taken together, the KDAI displayed excellent psychometric indices and sensitivity as a screening tool for IA in adolescents. © 2021 |
Behavioral addiction; Psychometric characteristic; Screening instrument; Self-report |
adolescent; adult; Article; child; concurrent validity; confirmatory factor analysis; controlled study; cultural anthropology; Delphi study; diagnostic accuracy; diagnostic test accuracy study; exploratory research; face validity; female; human; internet addiction; Internet Addiction Diagnostic Questionnaire; major clinical study; male; mood; pilot study; psychometry; questionnaire; receiver operating characteristic; reference value; reliability; scoring system; self report; sensitivity and specificity; validation study; addiction; Internet; internet addiction; questionnaire; reproducibility; Adolescent; Behavior, Addictive; Humans; Internet; Internet Addiction Disorder; Pilot Projects; Reproducibility of Results; Surveys and Questionnaires |
Elsevier Ireland Ltd |
01651781 |
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33662841 |
Article |
Q1 |
1224 |
3201 |
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492 |
Maulidina F., Rustam Z., Hartini S., Wibowo V.V.P., Wirasati I., Sadewo W. |
57221906584;26422482100;57211529061;57221911837;57221806240;55014544900; |
Feature optimization using Backward Elimination and Support Vector Machines (SVM) algorithm for diabetes classification |
2021 |
Journal of Physics: Conference Series |
1821 |
1 |
012006 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103897338&doi=10.1088%2f1742-6596%2f1821%2f1%2f012006&partnerID=40&md5=26c4c2f598bd765549c0283978c63185 |
Departement of Mathematics, University of Indonesia, Depok, 16424, Indonesia; Department of Neurosurgery, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Indonesia |
Maulidina, F., Departement of Mathematics, University of Indonesia, Depok, 16424, Indonesia; Rustam, Z., Departement of Mathematics, University of Indonesia, Depok, 16424, Indonesia; Hartini, S., Departement of Mathematics, University of Indonesia, Depok, 16424, Indonesia; Wibowo, V.V.P., Departement of Mathematics, University of Indonesia, Depok, 16424, Indonesia; Wirasati, I., Departement of Mathematics, University of Indonesia, Depok, 16424, Indonesia; Sadewo, W., Department of Neurosurgery, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Indonesia |
Diabetes is a disease that occurs when the blood glucose level is higher than normal and also leads to health problems. Early and accurate diagnosis needs to be carried out on individuals affected by this disease. Furthermore, excellent treatment needs to be provided to prevent worse situations. Some studies have used several machine learning methods to diagnose diabetes. Furthermore, in this study, the Backward Elimination and Support Vector Machine (SVM) algorithm was used to classify the PIMA Indians diabetes dataset. It consisted of 268 diabetic and 500 non-diabetic patients with eight attributes. Backward Elimination is a feature selection method used to remove irrelevant features based on the linear regression model. Using this method, the right features for the model was expected. This method has some advantages which include increasing training time, decreasing complexity and improving performance and accuracy. Therefore, the performance of SVM improved. Based on the experiments, it was discovered that by combining feature selection algorithm (backward elimination) and SVM, the highest accuracy obtained was 85.71% using 90% data training. Therefore, it was concluded that Backward Elimination combined with SVM algorithm is an excellent method to classify diabetes by using the PIMA Indians diabetes dataset. © Published under licence by IOP Publishing Ltd. |
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Classification (of information); Diagnosis; Experimental mineralogy; Feature extraction; Learning systems; Regression analysis; Feature optimizations; Feature selection algorithm; Feature selection methods; Improving performance; Linear regression models; Machine learning methods; Support vector machine algorithm; Support vector machines algorithms; Support vector machines |
IOP Publishing Ltd |
17426588 |
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Conference Paper |
Q4 |
210 |
18731 |
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493 |
Wibowo V.V.P., Rustam Z., Hartini S., Maulidina F., Wirasati I., Sadewo W. |
57221911837;26422482100;57211529061;57221906584;57221806240;55014544900; |
Ovarian cancer classification using K-Nearest Neighbor and Support Vector Machine |
2021 |
Journal of Physics: Conference Series |
1821 |
1 |
012007 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103891589&doi=10.1088%2f1742-6596%2f1821%2f1%2f012007&partnerID=40&md5=8b428e7f3e510029f71b6c464cefbd2d |
Department of Mathematics, University of Indonesia, Depok, 16424, Indonesia; Department of Neurosurgery, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Indonesia |
Wibowo, V.V.P., Department of Mathematics, University of Indonesia, Depok, 16424, Indonesia; Rustam, Z., Department of Mathematics, University of Indonesia, Depok, 16424, Indonesia; Hartini, S., Department of Mathematics, University of Indonesia, Depok, 16424, Indonesia; Maulidina, F., Department of Mathematics, University of Indonesia, Depok, 16424, Indonesia; Wirasati, I., Department of Mathematics, University of Indonesia, Depok, 16424, Indonesia; Sadewo, W., Department of Neurosurgery, Faculty of Medicine, University of Indonesia, Dr. Cipto Mangunkusumo National General Hospital, Indonesia |
Ovarian cancer is one of the common malignancies in women and a known cause of death. This condition occurs when a tumor appears from the growth of abnormal cells in the ovary. It causes about 140.000 deaths out of 225.000 cases annually. Most women with ovarian cancer do not have distinctive signs and symptoms even at the late stage. Therefore, diagnosis at an early stage is necessary because it has a significant impact on the survival rate. Machine learning with various methods can be used in the medical field to classify diseases. Among the many methods, K-Nearest Neighbor (KNN) and Support Vector Machine (SVM) were used and analyzed in this study to classify ovarian cancer. The data used were from Al Islam Bandung Hospital consisting of 203 instances with 130 labeled ovarian cancer and 73 as non-ovarian. The results showed that the KNN produced higher results than SVM with 90.47% of accuracy and 94.11% of F1-score, while SVM produced accuracy and F1-score values of 90.47% and 92.30% respectively. © Published under licence by IOP Publishing Ltd. |
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Diagnosis; Diseases; Motion compensation; Nearest neighbor search; F1 scores; K nearest neighbor (KNN); K-nearest neighbors; Late stage; Medical fields; Ovarian cancers; Survival rate; Support vector machines |
IOP Publishing Ltd |
17426588 |
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Conference Paper |
Q4 |
210 |
18731 |
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495 |
Nadhif M.H., Assyarify H., Irsyad M., Pramesti A.R., Suhaeri M. |
57189057498;57220927630;57220935587;57222624921;56183087500; |
Recent advances in 3D printed wound dressings |
2021 |
AIP Conference Proceedings |
2344 |
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020021 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103522380&doi=10.1063%2f5.0047183&partnerID=40&md5=494f3e384ff38d4974127c234d704499 |
Medical Technology Cluster, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, DKI Jakarta, 10430, Indonesia; Department of Medical Physics, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, DKI Jakarta, 10430, Indonesia; Unit of Education, Research, and Training, Universitas Indonesia Hospital, Universitas Indonesia, Jl. Salemba Raya No. 6, DKI Jakarta, 10430, Indonesia |
Nadhif, M.H., Medical Technology Cluster, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, DKI Jakarta, 10430, Indonesia, Department of Medical Physics, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, DKI Jakarta, 10430, Indonesia; Assyarify, H., Medical Technology Cluster, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, DKI Jakarta, 10430, Indonesia; Irsyad, M., Medical Technology Cluster, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, DKI Jakarta, 10430, Indonesia; Pramesti, A.R., Medical Technology Cluster, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, DKI Jakarta, 10430, Indonesia; Suhaeri, M., Medical Technology Cluster, Indonesia Medical Education and Research Institute (IMERI), Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, DKI Jakarta, 10430, Indonesia, Unit of Education, Research, and Training, Universitas Indonesia Hospital, Universitas Indonesia, Jl. Salemba Raya No. 6, DKI Jakarta, 10430, Indonesia |
Chronic and acute wounds interfere with personal aesthetics and appearance. Regarding the problematics, researchers enhance the functionalities of wound dressings. One of the enhancement approaches is using 3D printing technology. The use of 3D printing has enabled many types of wound dressings, including biodegradable multi-material, cell-laden, and drug-eluting wound dressings. The use of 3D printing even allows for a wound dressing with a 3D construct, facilitating the wound dressing placement at the wound bed. Unfortunately, the 3D printed wound dressing technology has never been reviewed, to the extent of our knowledge. In this report, we aim to reflect on the recent advances in 3D printed wound dressings. Reports regarding the 3D printed wound dressing were collected from the Google Scholar database. The search was limited from 2015 to 2020 with a logic search: "3D printed"AND "wound dressing,"which words can be found in the entire article. Irrelevant reports were excluded manually, thereby resulting in the 24 selected articles. The selected articles were subsequently reviewed in terms of the materials-efficacy analysis and 3D printing mechanism. The extracted information from all articles concluded that alginate is the most used material for 3D printed wound dressing, while the most used 3D printing mechanism is the pneumatic FDM. In terms of efficacy, wound dressings presented an antimicrobial performance against Gram-positive and Gram-negative bacteria, as well as biocompatibility to epidermis and dermis cells. © 2021 Author(s). |
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American Institute of Physics Inc. |
0094243X |
9780735440869 |
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Conference Paper |
- |
177 |
20880 |
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