No records
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731 |
Raharjo D.E., Kunadian V. |
57212958767;55390915800; |
Is There a Difference in Efficacy of Percutaneous Coronary Intervention for Focal and Diffuse Stable Coronary Artery Disease? |
2021 |
Circulation: Cardiovascular Interventions |
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011013 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85113224581&doi=10.1161%2fCIRCINTERVENTIONS.121.011013&partnerID=40&md5=d51bf48934551b00e2a6df5c69fb0e80 |
Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom; Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Cardiothoracic Centre, Freeman Hospital, Newcastle Upon Tyne Hospitals NHS Foundation Trust, United Kingdom |
Raharjo, D.E., Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Kunadian, V., Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom, Cardiothoracic Centre, Freeman Hospital, Newcastle Upon Tyne Hospitals NHS Foundation Trust, United Kingdom |
[No abstract available] |
coronary artery disease; Editorials; heart disease; morbidity; percutaneous coronary intervention |
adverse event; coronary artery bypass graft; coronary artery disease; diagnostic imaging; human; percutaneous coronary intervention; Coronary Artery Bypass; Coronary Artery Disease; Humans; Percutaneous Coronary Intervention |
Lippincott Williams and Wilkins |
19417640 |
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34340524 |
Review |
Q1 |
2621 |
832 |
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736 |
Sulaiman A.S., Gani R.A., Hasan I., Lesmana C.R.A., Kurniawan J., Jasirwan C.O.M., Kalista K.F., Nababan S.H.H., Aprilicia G., Lesmana L.A. |
57216938482;23495930300;12776850800;8977683000;57193251655;55192478000;57200425631;57205443199;57212764287;55920139300; |
Overall Survival of Hepatocellular Carcinoma Patients Underwent Radiofrequency Ablation (RFA) Treatment: a Retrospective Cohort Study from Two Referral Hospitals in Indonesia |
2021 |
Journal of Gastrointestinal Cancer |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85112279138&doi=10.1007%2fs12029-021-00676-0&partnerID=40&md5=2b5f131ccaeb172f51ae448108c59f48 |
Hepatobiliary Division, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Digestive Disease and GI Oncology Center, Medistra, Jakarta, Indonesia |
Sulaiman, A.S., Hepatobiliary Division, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Gani, R.A., Hepatobiliary Division, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Hasan, I., Hepatobiliary Division, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Lesmana, C.R.A., Hepatobiliary Division, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Kurniawan, J., Hepatobiliary Division, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Jasirwan, C.O.M., Hepatobiliary Division, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Kalista, K.F., Hepatobiliary Division, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Nababan, S.H.H., Hepatobiliary Division, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Aprilicia, G., Hepatobiliary Division, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo National General Hospital, Jakarta, Indonesia; Lesmana, L.A., Digestive Disease and GI Oncology Center, Medistra, Jakarta, Indonesia |
Background: Radiofrequency ablation (RFA) is one of the curative modality therapies commonly used for the early stage of HCC management. Although numerous studies have reported the outcome of RFA around the world, the data regarding the usage of RFA for the early and intermediate stage of HCC remains limited. Hence, the study aimed to report the survival rate of the early and intermediate stage HCC patients who underwent RFA in two tertiary referral hospitals in Jakarta, Indonesia. Methods: A retrospective cohort study was conducted in Cipto Mangunkusumo and Medistra multicenter hospital in Jakarta, Indonesia. The patients with HCC BCLC A and B who underwent RFA treatments between January 2015 to December 2017 were recruited for the study. Baseline characteristics of patients were collected from the medical record. Survival analysis was calculated using the Kaplan Meier. p value result was obtained from the log-rank test. Sub-analysis of factors associated with the survival was also included in this study. Results: There were 62 patients enrolled in this study (32.3% were BCLC A and 67.7% were BCLC B). Forty-six out of 62 patients (74.2%) were reported to have RFA as their first line of treatment, while 12 (25.8%) were reported to have a combination of RFA and other therapy modalities. All these patients were follow-up with an average duration of 27 months. The survival rate of liver cancer due to HCC for 12 and 36 months in patients who received RFA was 82.3% and 57.8%, respectively. Moreover, BCLC staging of liver cancer and response after RFA was significantly associated with survival. Conclusion: RFA still can be used as initial modality therapy nor combination with another therapy for the early and intermediate stage of HCC. BCLC staging and response after RFA had shown to be the independent factors related to survival. © 2021, Springer Science+Business Media, LLC, part of Springer Nature. |
Early stage and intermediate stage of liver cancer; Radiofrequency ablation; Survival rate |
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Springer |
19416628 |
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Article |
Q3 |
473 |
10563 |
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739 |
Kamal A.F., Ramang D.S., Prasetyo M. |
56648996700;57195942455;57192905252; |
Thromboembolism in Malignant Musculoskeletal Tumour: A Literature Review |
2021 |
Advances in Orthopedics |
2021 |
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6678167 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111946705&doi=10.1155%2f2021%2f6678167&partnerID=40&md5=d8f7af261692ce3cb5b68127f841fbe3 |
Department of Orthopaedic and Traumatology, Universitas Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Department of Radiology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Kamal, A.F., Department of Orthopaedic and Traumatology, Universitas Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Ramang, D.S., Department of Orthopaedic and Traumatology, Universitas Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia; Prasetyo, M., Department of Radiology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, Indonesia |
Malignant musculoskeletal tumour may cause considerable burden to general health. The fast growth combined with the tumour characteristics and its invasion capability resulted in the poor prognosis of malignant musculoskeletal tumour. Malignant musculoskeletal tumour may cause significant disability by destroying normal tissue that plays important role in body kinematics. Thromboembolism, including deep vein thrombosis, pulmonary embolism, and other kinds of venous thromboembolism, is one of the most underestimated complications of musculoskeletal tumour. Normally, thrombosis ensues when pathologic factors overcame the body hemostatic regulatory capabilities, which will predispose the body to the formation of thrombus. Venous thromboembolism in musculoskeletal tumour may develop as a result of interaction between the tumour pathologic capabilities and its interaction with normal bodily functions. In this study, we reviewed the burden of musculoskeletal tumour and its complication on global health. Then, the review will focus on the pathologic and clinical aspect of thromboembolism in malignant musculoskeletal tumour, including pathophysiology, diagnosis, and treatment based on recent findings and literature. © 2021 Achmad Fauzi Kamal et al. |
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acetylsalicylic acid; antineoplastic agent; low molecular weight heparin; tranexamic acid; blood examination; bone metastasis; cancer chemotherapy; clinical feature; drug cost; dynamic contrast-enhanced magnetic resonance imaging; echography; global health; human; locomotor system cancer; Medline; pathophysiology; patient compliance; Review; ScienceDirect; Scopus; SpringerLink; systematic review; thromboembolism; thrombosis prevention; tumor thrombus; venous thromboembolism |
Hindawi Limited |
20903464 |
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Review |
Q2 |
681 |
7334 |
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741 |
Sandora N., Putra M.A., Busro P.W., Ardiansyah, Muttaqin C., Makdinata W., Fitria N.A., Kusuma T.R. |
57204103434;57215605850;57192273817;57223036386;57226442135;57223405655;57148498800;57222897694; |
Preparation of Cell-Seeded Heart Patch In Vitro; Co-Culture of Adipose-Derived Mesenchymal Stem Cell and Cardiomyocytes in Amnion Bilayer Patch |
2021 |
Cardiovascular Engineering and Technology |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111590228&doi=10.1007%2fs13239-021-00565-4&partnerID=40&md5=cd6477f9e1ad4b1bf0110d68c68a71fc |
Institute of Medical Education and Research Indonesia, Jakarta, 10430, Indonesia; Department of Thoracic Surgery, RSCM, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Sandora, N., Institute of Medical Education and Research Indonesia, Jakarta, 10430, Indonesia; Putra, M.A., Department of Thoracic Surgery, RSCM, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Busro, P.W., Department of Thoracic Surgery, RSCM, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Ardiansyah, Department of Thoracic Surgery, RSCM, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Muttaqin, C., Department of Thoracic Surgery, RSCM, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Makdinata, W., Department of Thoracic Surgery, RSCM, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Fitria, N.A., Institute of Medical Education and Research Indonesia, Jakarta, 10430, Indonesia; Kusuma, T.R., Institute of Medical Education and Research Indonesia, Jakarta, 10430, Indonesia |
Introduction: Cardiovascular disease is the second killer across the globe, while coronary disease is the major cause. Cell therapy is one alternative to regenerate the infarcted heart wall. Materials and Methods: In this study, the cardiomyogenesis capacity of human adipose stem cells (hAdSC) and human cardiomyocytes (hCardio) cultured in a 3-D biological scaffold (decellularised amnion bilayer) for nine days in a static condition was investigated. The cardiomyogenesis capacity of hAdSC were identified using immunohistochemistry and RT-PCR. The population of the cells isolated from the heart tissue expressed cTnT-1 (13.38 ± 11.38%), cKit (7.85 ± 4.2%), ICAM (85.53 ± 8.69%), PECAM (61.63 ± 7.18%) and VCAM (35.9 ± 9.11%), while from the fat tissue expressed the mesenchymal phenotypes (CD73, CD90, CD105, but not CD45, CD34, CD11b, CD19 and HLA-DR). Two age groups of hAdSC donors were compared, the youngsters (30-40yo) and the elderly (60–70 yo). Results: The co-culture showed that after 5-day incubation, the seeded graft in the hAdSC-30 group had a tube-like appearance while the hAdSC-60 group demonstrated a disorganised pattern, despite of the MSC expressions of the hAdSC-60 were significantly higher. Initial co-culture showed no difference of ATP counts among all groups, however the hAdSC-30 group had the highest ATP count after 9 days culture (p = 0.004). After normalising to the normal myocardium, only the hAdSC-60 group expressed cTnT and MHC, very low, seen during the initial cultivation, but then disappeared. Meanwhile, the hAdSC-30 group expressed α-actinin, MHC and cTnT in the Day-5. The PPAR also was higher in the Day-5 compared to the Day-9 (p < 0.005). Conclusion: Cardiomyogenesis capacity of hAdSC co-cultured with hCardio in a 3-D scaffold taken from the 30–40yo donor showed better morphology and viability than the 60-70yo group, but maintained less than 5 days in this system. © 2021, Biomedical Engineering Society. |
3-D scaffold; Amnion bilayer; Human adipose stem cells; Human cardiomyocytes; Myocardial infarction |
Cell culture; Heart; Stem cells; Tissue; Adipose-derived mesenchymal stem cells; Biological scaffolds; Cardio-vascular disease; Cardiomyogenesis; Coronary disease; Human adipose stem cells; Immunohistochemistry; Static conditions; Scaffolds (biology) |
Springer |
1869408X |
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Article |
Q3 |
541 |
9343 |
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742 |
Paramaiswari W.T., Sidik N.S., Khoeri M.M., Tafroji W., Said W.F., Safari D. |
57221097580;57226416343;55994827400;57118271600;57196217927;23493586700; |
Isolation and Identification of Optochin-Resistant Viridans Group Streptococci from the Sputum Samples of Adult Patients in Jakarta, Indonesia |
2021 |
International Journal of Microbiology |
2021 |
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6646925 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111490612&doi=10.1155%2f2021%2f6646925&partnerID=40&md5=b022c6984c9b9cf061564ebeaeeb4831 |
Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Department of Biochemistry, Bogor Agricultural University, Bogor, Indonesia; Department of Clinical Pathology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Paramaiswari, W.T., Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Sidik, N.S., Department of Biochemistry, Bogor Agricultural University, Bogor, Indonesia; Khoeri, M.M., Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Tafroji, W., Eijkman Institute for Molecular Biology, Jakarta, Indonesia; Said, W.F., Department of Clinical Pathology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Safari, D., Eijkman Institute for Molecular Biology, Jakarta, Indonesia |
Aim. To investigate optochin-resistant viridans group streptococci (VGS) strains isolated from the sputum sample of adult patients with different clinical symptoms. Materials and Methods. Optochin-resistant VGS isolates were identified by matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF MS). recA sequencing was used to confirm identified isolates at the genus level by MALDI-TOF MS. Finding. We identified 79% of tested isolates (148/187) at the species-level identification using the MALDI-TOF MS tool. We identified that the most common species isolated from sputum specimens were S. oralis (44.9%) followed by S. mitis (25.7%), S. infantis (9.1%), S. parasanguinis (7.5%), S. peroris (3.7%), S. anginosus (2.7%), and S. sanguinis (2.1%). Discussion. The S. oralis strains were majority of optochin-resistant VGS isolates obtained from sputum of adult patients in Jakarta, Indonesia. MALDI-TOF MS showed potential for the rapid identification tool to identify optochin-resistant VGS isolates. Although there were discrepancies in identifying isolates at the genus/species level, the performance could be improved by expanding its database. © 2021 Wisiva Tofriska Paramaiswari et al. |
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Hindawi Limited |
1687918X |
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Article |
Q3 |
696 |
7161 |
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750 |
Amalia R., Bustamam A., Yudantha A.R., Victor A.A. |
57226194312;36815737800;55489644900;57191055282; |
Diabetic retinopathy detection and captioning based on lesion features using deep learning approach |
2021 |
Communications in Mathematical Biology and Neuroscience |
2021 |
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59 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110864476&doi=10.28919%2fcmbn%2f5832&partnerID=40&md5=e3e95d1370fc8ff4347362007e9add2e |
Department of Mathematics, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Depok, 16424, Indonesia; Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia Cipto Mangunkusumo National General Hospital, Jakarta Pusat, 10430, Indonesia |
Amalia, R., Department of Mathematics, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Depok, 16424, Indonesia; Bustamam, A., Department of Mathematics, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Depok, 16424, Indonesia; Yudantha, A.R., Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia Cipto Mangunkusumo National General Hospital, Jakarta Pusat, 10430, Indonesia; Victor, A.A., Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia Cipto Mangunkusumo National General Hospital, Jakarta Pusat, 10430, Indonesia |
Diabetic Retinopathy (DR) can lead to vision loss if the patient does not get effective treatment based on the patient’s condition. Early detection is needed to know what an effective treatment for those patients is. For helping ophthalmologists, DR detection methods using computer-based were developed. Ophthalmologists can use the result of the method as a consideration in diagnosing the class of DR. One of the powerful methods is deep learning. The proposed method uses two deep learning architectures, namely Convolutional Neural Network (CNN) and Recurrent Neural Network (RNN), for DR detection. CNN is used to detect DR lesion features, and RNN is used for captioning based on those lesion features. We used three pre-trained CNN models, including AlexNet, VGGNet and GoogleNet, and used Long Short-Term Memory (LSTM) as RNN models. In the image preprocessing, we applied contrast enhancement using Contrast Limited Adaptive Histogram Equalization (CLAHE) and compared the results with those without CLAHE. We have done the training and testing process with a different proportion of data. The experimental results show that our proposed method can detect the lesion features and generate caption with the highest average accuracy of 96.12% for GoogleNet and LSTM with CLAHE and the proportion 70% training data 30% testing data. © 2021 the author(s). |
Convolutional neural network (CNN); Deep learning; Diabetic retinopathy; Long short-term memory (LSTM) |
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SCIK Publishing Corporation |
20522541 |
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Article |
Q4 |
189 |
20081 |
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758 |
Auerkari E.I., Maulani C., C. Masulili S.L., Santoso W.D., Soedarsono N., Kusdhany L. |
10139113000;57205060934;57226076327;6506080422;14049161500;55301180900; |
Association of subgingival Epstein-Barr virus and periodontitis |
2021 |
F1000Research |
10 |
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414 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110298348&doi=10.12688%2ff1000research.52624.2&partnerID=40&md5=d21a6f40dceec542152f1e950acf5922 |
Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Periodontology, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Oral Biology, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Prosthodontics, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia |
Auerkari, E.I., Department of Oral Biology, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia; Maulani, C., Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia; C. Masulili, S.L., Department of Periodontology, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia; Santoso, W.D., Department of Internal Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Soedarsono, N., Department of Oral Biology, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia; Kusdhany, L., Department of Prosthodontics, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia |
Background: The Epstein-Barr virus (EBV) is gaining interest as a possible agent in the etiology of periodontitis. Previous studies have shown controversy on whether EBV DNA in the subgingival periodontal pockets is associated with periodontitis. The present study aimed to seek the potential relationship between EBV and periodontitis. Methods: Samples were taken from gingival crevicular fluid using sterile paper points, and data on sociodemographics, oral health, and periodontal health were recorded. This case-control study of 118 participants included 59 subjects with severe periodontitis and 59 control subjects with mild periodontitis. Quantitative real-time PCR was used to determined EBV load. Results: EBV DNA was detected in 37.3% of the case samples and 18.6% of the control samples. There was no significant difference in a load of EBV DNA between severe and mild periodontitis (p>0.05). The observed load of EBV DNA was up to 4.55x10 5 copies/mL. The detected EBV DNA was significantly associated with the plaque index and the oral hygiene index (p<0.05). Conclusions: Although no significant association was found, EBV may play a role in periodontitis. The real-time PCR methods can be used to monitor the EBV load in gingival crevicular fluid. © 2021 Maulani C et al. |
Epstein-Barr Virus; Gingival Crevicular Fluid; Periodontitis |
adult; aged; Article; case control study; cementoenamel junction; clinical attachment level; controlled study; demography; dental caries; DNA extraction; enzyme immunoassay; Epstein Barr virus; female; gingiva bleeding; gingivitis; health; human; hygiene; lactation; major clinical study; male; mouth hygiene; nonhuman; oral hygiene index; oral hygiene index simplified; peer review; periodontal pocket depth; periodontitis; plaque index; proteomics; real time polymerase chain reaction; regulatory T lymphocyte; tooth root canal |
F1000 Research Ltd |
20461402 |
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34316360 |
Article |
Q1 |
1099 |
3793 |
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761 |
Lesmana C.R.A., Paramitha M.S., Gani R.A. |
8977683000;57212562901;23495930300; |
The Role of Interventional Endoscopic Ultrasound in Liver Diseases: What Have We Learnt? |
2021 |
Canadian Journal of Gastroenterology and Hepatology |
2021 |
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9948979 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85110213187&doi=10.1155%2f2021%2f9948979&partnerID=40&md5=a038d06d78df9e699aa4a27ead88d0bb |
Department of Internal Medicine, Hepatobiliary Division, Dr. Cipto Mangunkusumo National General Hospital, Universitas Indonesia, Jakarta, Indonesia; Digestive Disease and GI Oncology Center, Medistra Hospital, Jakarta, Indonesia |
Lesmana, C.R.A., Department of Internal Medicine, Hepatobiliary Division, Dr. Cipto Mangunkusumo National General Hospital, Universitas Indonesia, Jakarta, Indonesia, Digestive Disease and GI Oncology Center, Medistra Hospital, Jakarta, Indonesia; Paramitha, M.S., Department of Internal Medicine, Hepatobiliary Division, Dr. Cipto Mangunkusumo National General Hospital, Universitas Indonesia, Jakarta, Indonesia; Gani, R.A., Department of Internal Medicine, Hepatobiliary Division, Dr. Cipto Mangunkusumo National General Hospital, Universitas Indonesia, Jakarta, Indonesia |
Chronic liver disease (CLD) is still a major problem, where the disease progression will lead to liver cirrhosis (LC) or hepatocellular carcinoma (HCC). Portal hypertension (PH) management and loco-regional therapy for HCC have become the cornerstones in advanced liver disease management. Recently, there are studies looking at the potential role of interventional endoscopic ultrasound (EUS) in liver diseases. EUS may be useful in vascular changes of the digestive wall evaluation, performing dynamic assessment of hemodynamic changes, predicting variceal bleeding and rebleeding risk, and assessing the pharmacological effects. In PH management, EUS-guided vascular therapy - which revolves around glue injection, endovascular coil placement/embolization, and combination of both - has shown promising results. As a diagnostic modality for liver cancer, the implementation of EUS in liver diseases is currently not only limited to liver biopsy (EUS-LB) but also in shear-wave elastography (SWE) and portal pressure gradient measurement, as well as portal vein sampling. The application of EUS-guided radiofrequency ablation (EUS-RFA) and tumor injection can also overcome the limitations shown by both modalities without EUS. Nevertheless, establishing EUS as a firm diagnostic and therapeutic modality is still challenging since the performance of interventional EUS requires high expertise and adequate facilities. © 2021 Cosmas Rinaldi A. Lesmana et al. |
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azygos vein; brachytherapy; chronic liver disease; contrast-enhanced ultrasound; cryotherapy; Doppler flowmetry; elastography; endoscopic ultrasonography; gastrointestinal hemorrhage; human; liver abscess; liver biopsy; liver cirrhosis; liver injury; liver metastasis; nonhuman; paracentesis; peritonitis; portal vein blood pressure; predictive value; radiation exposure; regional perfusion; Review; risk assessment; sclerotherapy; sensitivity and specificity; shear wave elastography; splanchnic blood flow; diagnostic imaging; endoscopic ultrasonography; esophagus varices; interventional ultrasonography; liver cell carcinoma; liver tumor; tumor recurrence; Carcinoma, Hepatocellular; Endosonography; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Liver Neoplasms; Neoplasm R |
Hindawi Limited |
22912789 |
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34258255 |
Review |
Q2 |
921 |
4950 |
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765 |
Tan J.W.C., Chew D.P., Brieger D., Eikelboom J., Montalescot G., Ako J., Kim B.-K., Quek D.K.L., Aitken S.J., Chow C.K., Chour S., Tse H.F., Kaul U., Firdaus I., Kubo T., Liew B.W., Chong T.T., Sin K.Y.K., Yeh H.-I., Buddhari W., Chunhamaneewat N., Hasan F., Fox K.A.A., Nguyen Q.N., Lo S.T.H. |
14829599000;7102026332;7004107910;7006303000;7102302494;6701389098;35189204900;57213290935;57225921713;8871779800;57225956090;7006070805;7102340294;55796864700;57226325834;57205155828;36609879000;57223949258;57225966367;57192991797;6505509528;57225971750;57224650893;39962151600;7401542169; |
2020 Asian Pacific Society of Cardiology Consensus Recommendations on Antithrombotic Management for High-risk Chronic Coronary Syndrome |
2021 |
European Cardiology Review |
16 |
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e26 |
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3 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109820982&doi=10.15420%2fECR.2020.45&partnerID=40&md5=349f92694e4c018a59343a627d38ced6 |
National Heart Centre, Singapore, Singapore; Sengkang General Hospital, Singapore, Singapore; College of Medicine and Public Health, Flinders University, Adelaide, Australia; Concord Repatriation General Hospital, University of Sydney, Sydney, Australia; McMaster UniversityON, Canada; Sorbonne University, Paris, France; ACTION Study Group, France; Pitié-Salpêtrière University Hospital (AP-HP), Paris, France; Kitasato University and Hospital, Kanagawa, Japan; Yonsei University College of Medicine, South Korea; Pantai Hospital Kuala Lumpur, Kuala Lumpur, Malaysia; University of Sydney, Sydney, Australia; Westmead Applied Research Centre, University of Sydney, Sydney, Australia; Westmead Hospital, Sydney, Australia; Calmette Hospital, Phnom Penh, Cambodia; Queen Mary Hospital, University of Hong Kong, Hong Kong; Batra Hospital and Medical Research Center, New Delhi, India; Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Wakayama Medical University, Wakayama, Japan; Changi General Hospital, Singapore, Singapore; Singapore General Hospital, Singapore, Singapore; MacKay Memorial Hospital, MacKay Medical College, Taipei, Taiwan; King Chulalongkorn Memorial Hospital, Bangkok, Thailand; Siriraj Hospital, Mahidol University, Bangkok, Thailand; Heart & Vascular Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates; University of Edinburgh, Edinburgh, United Kingdom; Hanoi Medical University, Vietnam National Heart Institute, Hanoi, Viet Nam; Liverpool Hospital, Sydney, Australia |
Tan, J.W.C., National Heart Centre, Singapore, Singapore, Sengkang General Hospital, Singapore, Singapore; Chew, D.P., College of Medicine and Public Health, Flinders University, Adelaide, Australia; Brieger, D., Concord Repatriation General Hospital, University of Sydney, Sydney, Australia; Eikelboom, J., McMaster UniversityON, Canada; Montalescot, G., Sorbonne University, Paris, France, ACTION Study Group, France, Pitié-Salpêtrière University Hospital (AP-HP), Paris, France; Ako, J., Kitasato University and Hospital, Kanagawa, Japan; Kim, B.-K., Yonsei University College of Medicine, South Korea; Quek, D.K.L., Pantai Hospital Kuala Lumpur, Kuala Lumpur, Malaysia; Aitken, S.J., University of Sydney, Sydney, Australia; Chow, C.K., Westmead Applied Research Centre, University of Sydney, Sydney, Australia, Westmead Hospital, Sydney, Australia; Chour, S., Calmette Hospital, Phnom Penh, Cambodia; Tse, H.F., Queen Mary Hospital, University of Hong Kong, Hong Kong; Kaul, U., Batra Hospital and Medical Research Center, New Delhi, India; Firdaus, I., Faculty of Medicine, University of Indonesia, Jakarta, Indonesia; Kubo, T., Wakayama Medical University, Wakayama, Japan; Liew, B.W., Changi General Hospital, Singapore, Singapore; Chong, T.T., Singapore General Hospital, Singapore, Singapore; Sin, K.Y.K., National Heart Centre, Singapore, Singapore; Yeh, H.-I., MacKay Memorial Hospital, MacKay Medical College, Taipei, Taiwan; Buddhari, W., King Chulalongkorn Memorial Hospital, Bangkok, Thailand; Chunhamaneewat, N., Siriraj Hospital, Mahidol University, Bangkok, Thailand; Hasan, F., Heart & Vascular Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates; Fox, K.A.A., University of Edinburgh, Edinburgh, United Kingdom; Nguyen, Q.N., Hanoi Medical University, Vietnam National Heart Institute, Hanoi, Viet Nam; Lo, S.T.H., Liverpool Hospital, Sydney, Australia |
The unique characteristics of patients with chronic coronary syndrome (CCS) in the Asia-Pacific region, heterogeneous approaches because of differences in accesses and resources and low number of patients from the Asia-Pacific region in pivotal studies, mean that international guidelines cannot be routinely applied to these populations. The Asian Pacific Society of Cardiology developed these consensus recommendations to summarise current evidence on the management of CCS and provide recommendations to assist clinicians treat patients from the region. The consensus recommendations were developed by an expert consensus panel who reviewed and appraised the available literature, with focus on data from patients in Asia-Pacific. Consensus statements were developed then put to an online vote. The resulting recommendations provide guidance on the assessment and management of bleeding and ischaemic risks in Asian CCS patients. Furthermore, the selection of long-term antithrombotic therapy is discussed, including the role of single antiplatelet therapy, dual antiplatelet therapy and dual pathway inhibition therapy. © 2021 Radcliffe Group Ltd. All rights reserved. |
Anticoagulant; Antiplatelet; Asia-Pacific; Bleeding; Chronic coronary syndrome; Consensus; Ischaemia |
acetylsalicylic acid; anticoagulant agent; clopidogrel; prasugrel; ticagrelor; age; anticoagulant therapy; Article; Asia; bleeding risk score; brain hemorrhage; cardiac patient; consensus; coronary artery disease; dual antiplatelet therapy; gastrointestinal hemorrhage; heart muscle ischemia; high risk patient; human; percutaneous coronary intervention; thrombosis |
Radcliffe Medical Media |
17583756 |
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Article |
Q2 |
864 |
5422 |
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767 |
Bachtiar E.W., Bachtiar B.M., Theodorea C.F., Tahapary D.L., Astrella C., Natalina N. |
6507328763;15831189400;57190048861;55944492500;57210793320;57225210620; |
A pilot study of red complex and three genera subgingival microbiome in periodontitis subjects with and without diabetes, evaluated by MinION platform |
2021 |
F1000Research |
10 |
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79 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109577307&doi=10.12688%2ff1000research.28216.3&partnerID=40&md5=83c85f319460a8e5631506acfe142095 |
Department of Oral Biology and Oral Science Research Center, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia; Division of Endocrinology, Department of Internal Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Metabolic, Cardiovascular and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Internal Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Periodontology, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia |
Bachtiar, E.W., Department of Oral Biology and Oral Science Research Center, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia; Bachtiar, B.M., Department of Oral Biology and Oral Science Research Center, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia; Theodorea, C.F., Department of Oral Biology and Oral Science Research Center, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia; Tahapary, D.L., Division of Endocrinology, Department of Internal Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Metabolic, Cardiovascular and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Astrella, C., Metabolic, Cardiovascular and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Department of Internal Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Natalina, N., Department of Periodontology, Faculty of Dentistry, Universitas Indonesia, Jakarta, 10430, Indonesia |
Background: Subgingival niche is one biofilm habitat containing rich microbiota, which plays an active role in maintaining the health of periodontal tissue and determining host response. As such, a study of changing subgingival biofilms is important for understanding the effect of a systemic condition. In this study, we compared the occurrence of six bacteria cohabiting in the subgingival area of periodontitis subjects, with (DP, n = 8) and without (NDP, n = 4) diabetes. Methods: The six genus and species of targeted bacteria were confirmed by 16S rRNA amplicon sequencing on MinION nanopore platform. Descriptive statistic was used to describe the obtained data. Results: We found that the six genus and species of targeted bacteria were detected but in different quantities in either group's periodontal pocket. Our data showed that Tannerella forsythia was the most abundant species in subgingival biofilms of the DP group of the red complex bacteria. In contrast, Aggregatibacter sp., which belongs to the phylum of proteobacteria, was present at a relatively lower level. In contrast, Fusobacterium sp., which belongs to orange complex bacteria, showed relative similarities in subgingival biofilms of both groups tested, while Veillonella sp., were abundant in the DP groups. Conclusions: Our data show that the diversity of classic periodontopathogens increased in the subgingival niche of periodontitis subjects with diabetes. It is the first study in Indonesia to apply MinION-based, full-length 16S rRNA amplicon sequencing in periodontitis patients with and without diabetes. © 2021 Bachtiar BM et al. |
16S rRNA; Diabetes; MinION; Periodontitis; Red Complex bacteria; Subgingival Microbiome |
RNA 16S; diabetes mellitus; genetics; gingiva; human; Indonesia; microflora; periodontitis; pilot study; Diabetes Mellitus; Gingiva; Humans; Indonesia; Microbiota; Periodontitis; Pilot Projects; RNA, Ribosomal, 16S |
F1000 Research Ltd |
20461402 |
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34249333 |
Article |
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1099 |
3793 |
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