No records
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311 |
Sunardi D., Bardosono S., Basrowi R.W., Wasito E., Vandenplas Y. |
57192075078;21933841000;57024210400;6506940239;57223670656; |
Dietary determinants of anemia in children aged 6–36 months: A cross-sectional study in Indonesia |
2021 |
Nutrients |
13 |
7 |
2397 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109524537&doi=10.3390%2fnu13072397&partnerID=40&md5=2e8ac565ce8b6f3dd3f70a2de509a9ad |
Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, 10430, Indonesia; Medical Nutrition for Danone Specialized Nutrition, Yogyakarta, 55165, Indonesia; Vrije Universiteit Brussel (VUB), UZ Brussels, KidZ Health Castle, Brussels, 1090, Belgium |
Sunardi, D., Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, 10430, Indonesia; Bardosono, S., Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo General Hospital, Jakarta, 10430, Indonesia; Basrowi, R.W., Medical Nutrition for Danone Specialized Nutrition, Yogyakarta, 55165, Indonesia; Wasito, E., Medical Nutrition for Danone Specialized Nutrition, Yogyakarta, 55165, Indonesia; Vandenplas, Y., Vrije Universiteit Brussel (VUB), UZ Brussels, KidZ Health Castle, Brussels, 1090, Belgium |
Anemia has been acknowledged as worldwide problem, including in Indonesia. This cross-sectional study aims to explore dietary determinants as risk factors for anemia in children aged 6–36 months living in a poor urban area of Jakarta. The study was done in Kampung Melayu sub-district in Jakarta, Indonesia. Data was collected within two weeks in September–October 2020. A structured questionnaire for a 24-h recall and a semi-quantitative Food Frequency Questionnaire (FFQ) were used to collect the dietary intake data, and venous blood was withdrawn to determine the hemoglobin levels. Bivariate chi-square and multiple logistic regression tests were executed to explore the dietary determinant factors for anemia. We recruited 180 subjects. The average hemoglobin concentration was 11.4 ± 1.7 mg/dL; the anemia prevalence was 29.4%. The following variables were significantly associated with higher risk of anemia: no cow’s milk formula consumption, inadequate intake of fats, protein, calcium, vitamin D, iron, zinc, vitamin A, vitamin C, vitamin B6, and vitamin B12. Only cow’s milk formula consumption and zinc intake were revealed as the determinant factors of anemia. In conclusion, the prevalence of anemia was 29.4% among children aged 6–36 months old. Anemia was significantly associated with two dietary determinants as risk factors that are cow’s milk formula consumption and zinc intake. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Anemia; Cow’s milk; Cow’s milk formula; Indonesia; Toddler; Zinc |
biological marker; hemoglobin; zinc; adverse event; age; anemia; artificial milk; blood; bottle feeding; cross-sectional study; diet; female; human; Indonesia; infant; infant nutrition; male; metabolism; nutritional status; pathophysiology; preschool child; prevalence; risk assessment; risk factor; urban health; Age Factors; Anemia; Biomarkers; Bottle Feeding; Child, Preschool; Cross-Sectional Studies; Diet; Diet Surveys; Female; Hemoglobins; Humans; Indonesia; Infant; Infant Formula; Infant Nutritional Physiological Phenomena; Male; Nutritional Status; Prevalence; Risk Assessment; Risk Factors; Urban Health; Zinc |
MDPI AG |
20726643 |
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34371908 |
Article |
Q1 |
1418 |
2497 |
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403 |
Fuady A., Nuraini N., Sukandar K.K., Lestari B.W. |
37085331400;24605696400;57216947725;56589945500; |
Targeted vaccine allocation could increase the covid-19 vaccine benefits amidst its lack of availability: A mathematical modeling study in indonesia |
2021 |
Vaccines |
9 |
5 |
462 |
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9 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105974918&doi=10.3390%2fvaccines9050462&partnerID=40&md5=4a9375c9281f8f4834500172552d5373 |
Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10310, Indonesia; Department of Public Health, Erasmus MC University Medical Center Rotterdam, Rotterdam, 3015 GD, Netherlands; Department of Mathematics, Institut Teknologi Bandung, Bandung, 40132, Indonesia; Epidemiology Group of COVID-19 Task Force for West Java, Bandung, 40171, Indonesia; Department of Public Health, Faculty of Medicine, Universitas Padjadjaran, Bandung, 40161, Indonesia; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, 6525 GA, Netherlands |
Fuady, A., Department of Community Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, 10310, Indonesia, Department of Public Health, Erasmus MC University Medical Center Rotterdam, Rotterdam, 3015 GD, Netherlands; Nuraini, N., Department of Mathematics, Institut Teknologi Bandung, Bandung, 40132, Indonesia, Epidemiology Group of COVID-19 Task Force for West Java, Bandung, 40171, Indonesia; Sukandar, K.K., Department of Mathematics, Institut Teknologi Bandung, Bandung, 40132, Indonesia; Lestari, B.W., Epidemiology Group of COVID-19 Task Force for West Java, Bandung, 40171, Indonesia, Department of Public Health, Faculty of Medicine, Universitas Padjadjaran, Bandung, 40161, Indonesia, Department of Internal Medicine, Radboud University Medical Center, Nijmegen, 6525 GA, Netherlands |
With a limited number of vaccines and healthcare capacity shortages, particularly in low-and middle-income countries, vaccination programs should seek the most efficient strategy to reduce the negative impact of the COVID-19 pandemics. This study aims at assessing several scenarios of delivering the vaccine to people in Indonesia. We develop a model for several scenarios of delivering vaccines: without vaccination, fair distribution, and targeted distribution to five and eight districts with the highest COVID-19 incidence in West Java, one of the most COVID-19-affected regions in Indonesia. We calculate the needs of vaccines and healthcare staff for the program, then simulate the model for the initial 4-month and one-year scenarios. A one-year vaccination program would require 232,000 inoculations per day by 4833 vaccinators. Targeted vaccine allocation based on the burden of COVID-19 cases could benefit the COVID-19 vaccination program by lowering at least 5000 active cases. The benefits would increase by improving the number of vaccines and healthcare staff. Amidst lacking available vaccines, targeted vaccine allocation based on the burden of COVID-19 cases could increase the benefit of the COVID-19 vaccination program but still requires progressive efforts to improve healthcare capacity and vaccine availability for optimal protection for people. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
COVID-19; Low-and middle-income countries; Modeling; Strategy; Vaccine |
SARS-CoV-2 vaccine; Article; coronavirus disease 2019; disease model; disease predisposition; disease transmission; drug bioavailability; drug efficacy; health care need; health care personnel; human; Indonesia; infection rate; mathematical model; mortality; quarantine; reinfection; resource allocation; SIQRD model; vaccination |
MDPI AG |
2076393X |
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|
Article |
Q1 |
1296 |
2913 |
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457 |
Rozaliyani A., Setianingrum F., Azahra S., Abdullah A., Fatril A.E., Rosianawati H., Burhan E., Handayani D., Arifin A.R., Zaini J., Tugiran M., Adawiyah R., Syam R., Wibowo H., Wahyuningsih R., Kosmidis C., Denning D.W. |
57203065912;57203061705;57219977463;57223138415;57223130315;57220203100;36058554600;57219413838;57223139966;57221833355;57218291154;57208658742;57218290535;57217690943;6507268400;16834840500;57223404509; |
Performance of ldbio aspergillus wb and ict antibody detection in chronic pulmonary aspergillosis |
2021 |
Journal of Fungi |
7 |
4 |
311 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105015900&doi=10.3390%2fjof7040311&partnerID=40&md5=d403a899e390ae45f6c1071eeb2d4832 |
Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, 13230, Indonesia; MH Thamrin Hospital, Jakarta, 10440, Indonesia; Department of Parasitology, Faculty of Medicine, Universitas Kristen, Jakarta, 13530, Indonesia; Manchester Academic Health Science Centre, Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, School of Biological Sciences, Medicine and Health, University of Manchester, Manchester, M23 9LT, United Kingdom |
Rozaliyani, A., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Setianingrum, F., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Azahra, S., Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Abdullah, A., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Fatril, A.E., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Rosianawati, H., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, 13230, Indonesia; Burhan, E., Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia, Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, 13230, Indonesia; Handayani, D., Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia, Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, 13230, Indonesia; Arifin, A.R., Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia, MH Thamrin Hospital, Jakarta, 10440, Indonesia; Zaini, J., Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia, Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan National Respiratory Referral Hospital, Jakarta, 13230, Indonesia; Tugiran, M., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Adawiyah, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Syam, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Wibowo, H., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia; Wahyuningsih, R., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Pulmonary Mycosis Centre, Jakarta, 10430, Indonesia, Department of Parasitology, Faculty of Medicine, Universitas Kristen, Jakarta, 13530, Indonesia; Kosmidis, C., Manchester Academic Health Science Centre, Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, School of Biological Sciences, Medicine and Health, University of Manchester, Manchester, M23 9LT, United Kingdom; Denning, D.W., Manchester Academic Health Science Centre, Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, School of Biological Sciences, Medicine and Health, University of Manchester, Manchester, M23 9LT, United Kingdom |
The detection of Aspergillus antibody has a key role in the diagnosis of chronic pulmonary as-pergillosis. Western blot (WB) and immunochromatography (ICT) lateral flow detection of Aspergillus antibody can be used as confirmatory and screening assays but their comparative performance in TB patients is not known. This study investigated the performance of these assays among 88 post-tuberculosis patients with suspected CPA. Sensitivity, specificity, receiver operating curve (ROC), area under-curve (AUC) and the agreement between two assays were evaluated. Both WB and ICT showed good sensitivity (80% and 85%, respectively) for detection of Aspergillus antibodies. Substantial agreement (0.716) between these assays was also obtained. The highest AUC result (0.804) was achieved with the combination of WB and ICT. The global intensity of WB correlated with the severity of symptoms in CPA group (p = 0.001). The combination of WB and ICT may increase specificity in CPA diagnosis. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Chronic pulmonary aspergillosis; Immunochromatography; Western blot |
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MDPI AG |
2309608X |
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Article |
Q1 |
1702 |
1800 |
|
|
467 |
Miftahussurur M., Doohan D., Syam A.F., Nusi I.A., Subsomwong P., Waskito L.A., Maulahela H., Akil F., Uwan W.B., Siregar G., Fauzia K.A., Rezkitha Y.A.A., Rahman A., Wibawa I.D.N., Saudale A.M.J., Richardo M., Sugihartono T., Chomariyati A., Bramantoro T., Uchida T., Yamaoka Y. |
56323903000;57204644036;8443384400;56543515200;57113712700;57192177367;57189612709;35191671700;57093988500;56483277100;57204649404;56543533600;57212819255;6504449940;57192179505;57207621686;57194156387;57222871823;57196010143;35286123100;55183784100; |
Cyp2c19 polymorphisms in indonesia: Comparison among ethnicities and the association with clinical outcomes |
2021 |
Biology |
10 |
4 |
300 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85104101307&doi=10.3390%2fbiology10040300&partnerID=40&md5=5c1d7696c67d83bbcf546211d5004bf0 |
Gastroentero-Hepatology Division, Department of Internal Medicine, Faculty of Medicine-Dr, Soetomo Teaching Hospital, Universitas Airlangga, Surabaya, 60286, Indonesia; Institute of Tropical Disease, Universitas Airlangga, Surabaya, 60115, Indonesia; Department of Environmental and Preventive Medicine, Oita University, Faculty of Medicine, Yufu, 879-5593, Japan; Department of Microbiology and Immunology, Hirosaki University Graduate School of Medicine, Aomori, Hirosaki, 036-8562, Japan; Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, University of Indonesia, Jakarta, 10430, Indonesia; Center of Gastroentero-Hepatology, Department of Internal Medicine, Faculty of Medicine, Hasanuddin University, Makassar, 90245, Indonesia; Department of Internal Medicine, Santo Antonius Hospital, Pontianak, 78243, Indonesia; Division of Gastroentero-Hepatology, Department of Internal Medicine, Faculty of Medicine, University of Sumatra Utara, Medan, 20155, Indonesia; Faculty of Medicine, University of Muhammadiyah Surabaya, Surabaya, 60113, Indonesia; Department of Internal Medicine, Kolaka General Hospital, Kolaka, 93511, Indonesia; Division of Gastroentero-Hepatology, Department of Internal Medicine, Faculty of Medicine, University of Udayana, Denpasar, 80232, Indonesia; Department of Internal Medicine, Prof. Dr. W. Z. Johannes General Hospital, Kupang, 85111, Indonesia; Department of Internal Medicine, Merauke City General Hospital, Merauke, 99613, Indonesia; Department of Dental Public Health, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, 60131, Indonesia; Department of Molecular Pathology, Oita University, Faculty of Medicine, Yufu, 879-5593, Japan; Global Oita Medical Advanced Research Center for Health, Oita University, Yufu, 879-5593, Japan; Department of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, TX 77030, United States |
Miftahussurur, M., Gastroentero-Hepatology Division, Department of Internal Medicine, Faculty of Medicine-Dr, Soetomo Teaching Hospital, Universitas Airlangga, Surabaya, 60286, Indonesia, Institute of Tropical Disease, Universitas Airlangga, Surabaya, 60115, Indonesia; Doohan, D., Institute of Tropical Disease, Universitas Airlangga, Surabaya, 60115, Indonesia, Department of Environmental and Preventive Medicine, Oita University, Faculty of Medicine, Yufu, 879-5593, Japan; Syam, A.F., Department of Microbiology and Immunology, Hirosaki University Graduate School of Medicine, Aomori, Hirosaki, 036-8562, Japan; Nusi, I.A., Gastroentero-Hepatology Division, Department of Internal Medicine, Faculty of Medicine-Dr, Soetomo Teaching Hospital, Universitas Airlangga, Surabaya, 60286, Indonesia; Subsomwong, P., Department of Environmental and Preventive Medicine, Oita University, Faculty of Medicine, Yufu, 879-5593, Japan, Department of Microbiology and Immunology, Hirosaki University Graduate School of Medicine, Aomori, Hirosaki, 036-8562, Japan; Waskito, L.A., Institute of Tropical Disease, Universitas Airlangga, Surabaya, 60115, Indonesia, Department of Environmental and Preventive Medicine, Oita University, Faculty of Medicine, Yufu, 879-5593, Japan; Maulahela, H., Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine, University of Indonesia, Jakarta, 10430, Indonesia; Akil, F., Center of Gastroentero-Hepatology, Department of Internal Medicine, Faculty of Medicine, Hasanuddin University, Makassar, 90245, Indonesia; Uwan, W.B., Department of Internal Medicine, Santo Antonius Hospital, Pontianak, 78243, Indonesia; Siregar, G., Division of Gastroentero-Hepatology, Department of Internal Medicine, Faculty of Medicine, University of Sumatra Utara, Medan, 20155, Indonesia; Fauzia, K.A., Institute of Tropical Disease, Universitas Airlangga, Surabaya, 60115, Indonesia, Department of Environmental and Preventive Medicine, Oita University, Faculty of Medicine, Yufu, 879-5593, Japan; Rezkitha, Y.A.A., Institute of Tropical Disease, Universitas Airlangga, Surabaya, 60115, Indonesia, Faculty of Medicine, University of Muhammadiyah Surabaya, Surabaya, 60113, Indonesia; Rahman, A., Department of Internal Medicine, Kolaka General Hospital, Kolaka, 93511, Indonesia; Wibawa, I.D.N., Division of Gastroentero-Hepatology, Department of Internal Medicine, Faculty of Medicine, University of Udayana, Denpasar, 80232, Indonesia; Saudale, A.M.J., Department of Internal Medicine, Prof. Dr. W. Z. Johannes General Hospital, Kupang, 85111, Indonesia; Richardo, M., Department of Internal Medicine, Merauke City General Hospital, Merauke, 99613, Indonesia; Sugihartono, T., Gastroentero-Hepatology Division, Department of Internal Medicine, Faculty of Medicine-Dr, Soetomo Teaching Hospital, Universitas Airlangga, Surabaya, 60286, Indonesia; Chomariyati, A., Gastroentero-Hepatology Division, Department of Internal Medicine, Faculty of Medicine-Dr, Soetomo Teaching Hospital, Universitas Airlangga, Surabaya, 60286, Indonesia; Bramantoro, T., Department of Dental Public Health, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, 60131, Indonesia; Uchida, T., Department of Molecular Pathology, Oita University, Faculty of Medicine, Yufu, 879-5593, Japan; Yamaoka, Y., Gastroentero-Hepatology Division, Department of Internal Medicine, Faculty of Medicine-Dr, Soetomo Teaching Hospital, Universitas Airlangga, Surabaya, 60286, Indonesia, Department of Environmental and Preventive Medicine, Oita University, Faculty of Medicine, Yufu, 879-5593, Japan, Global Oita Medical Advanced Research Center for Health, Oita University, Yufu, 879-5593, Japan, Department of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, TX 77030, United States |
CYP2C19 polymorphisms are important factors for proton pump inhibitor-based therapy. We examined the CYP2C19 genotypes and analyzed the distribution among ethnicities and clinical outcomes in Indonesia. We employed the polymerase chain reaction-restriction fragment length polymorphism method to determine the CYP2C19 genotypes and evaluated inflammation severity with the updated Sydney system. For CYP2C19*2, 46.4% were the homozygous wild-type allele, 14.5% were the homozygous mutated allele, and 39.2% were the heterozygous allele. For CYP2C19*3, 88.6% were the homozygous wild-type allele, 2.4% were the homozygous mutated allele, and 9.0% were the heterozygous allele. Overall, the prevalence of rapid, intermediate, and poor metabolizers in Indonesia was 38.5, 41.6, and 19.9%, respectively. In the poor metabolizer group, the frequency of allele *2 (78.8%) was higher than the frequency of allele *3 (21.2%). The Papuan had a significantly higher likelihood of possessing poor metabolizers than the Balinese (OR 11.0; P = 0.002). The prevalence of poor metabolizers was lower compared with the rapid and intermediate metabolizers among patients with gastritis and gastroesophageal reflux disease. Intermediate metabolizers had the highest prevalence, followed by rapid metabolizers and poor metabolizers. Dosage adjustment should therefore be considered when administering proton pump inhibitor-based therapy in Indonesia. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
CYP2C19; Gastritis; H. pylori; Infectious disease; Polymorphism |
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MDPI AG |
20797737 |
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Article |
Q1 |
1731 |
1747 |
|
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561 |
Nadzir M.M., Nurhayati R.W., Idris F.N., Nguyen M.H. |
8668648100;55748436600;57194239683;55319059400; |
Biomedical applications of bacterial exopolysaccharides: A review |
2021 |
Polymers |
13 |
4 |
530 |
1 |
25 |
|
9 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101211712&doi=10.3390%2fpolym13040530&partnerID=40&md5=0563148d938735dbc6e7b156a85abe90 |
School of Chemical Engineering, Engineering Campus, Universiti Sains Malaysia, Nibong Tebal, 14300, Malaysia; Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, 16424, Indonesia; Stem Cell and Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10430, Indonesia; Faculty of Biotechnology, Chemistry and Environmental Engineering, Phenikaa University, Hanoi, 12116, Viet Nam; Bioresource Research Center, Phenikaa University, Hanoi, 12116, Viet Nam |
Nadzir, M.M., School of Chemical Engineering, Engineering Campus, Universiti Sains Malaysia, Nibong Tebal, 14300, Malaysia; Nurhayati, R.W., Department of Chemical Engineering, Faculty of Engineering, Universitas Indonesia, Depok, 16424, Indonesia, Stem Cell and Tissue Engineering Research Cluster, Indonesian Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya No. 6, Jakarta, 10430, Indonesia; Idris, F.N., School of Chemical Engineering, Engineering Campus, Universiti Sains Malaysia, Nibong Tebal, 14300, Malaysia; Nguyen, M.H., Faculty of Biotechnology, Chemistry and Environmental Engineering, Phenikaa University, Hanoi, 12116, Viet Nam, Bioresource Research Center, Phenikaa University, Hanoi, 12116, Viet Nam |
Bacterial exopolysaccharides (EPSs) are an essential group of compounds secreted by bacteria. These versatile EPSs are utilized individually or in combination with different materials for a broad range of biomedical field functions. The various applications can be explained by the vast number of derivatives with useful properties that can be controlled. This review offers insight on the current research trend of nine commonly used EPSs, their biosynthesis pathways, their characteristics, and the biomedical applications of these relevant bioproducts. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Alginate; Bacteria; Biomedical; Cellulose; Dextran; Exopolysaccharides; Gellan; Hyaluronic acid; Levan; Xanthan gum |
Biochemistry; Bioproducts; Medical applications; Biomedical applications; Biomedical fields; Biosynthesis pathways; Exopolysaccharides; Research trends; Useful properties; Polysaccharides |
MDPI AG |
20734360 |
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|
Review |
Q1 |
770 |
6319 |
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582 |
Scheffler C., Hermanussen M., Soegianto S.D.P., Homalessy A.V., Touw S.Y., Angi S.I., Ariyani Q.S., Suryanto T., Matulessy G.K.I., Fransiskus T., Safira A.V.C., Puteri M.N., Rahmani R., Ndaparoka D.N., Payong M.K.E., Indrajati Y.D., Purba R.K.H., Manubulu R.M., Julia M., Pulungan A.B. |
22836040300;7005909056;57212268744;57209200014;57209199756;57221800920;57221801196;57221800170;57221808632;57221804338;57221806887;57221809375;57221807473;57221800477;57209199238;57221808668;57221803203;57221808341;14019743100;57192905981; |
Stunting as a synonym of social disadvantage and poor parental education |
2021 |
International Journal of Environmental Research and Public Health |
18 |
3 |
1350 |
1 |
13 |
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5 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100239177&doi=10.3390%2fijerph18031350&partnerID=40&md5=33700577101c6821f63520cfa18f471d |
Institute of Biochemistry and Biology, Human Biology, University of Potsdam, Potsdam, 14469, Germany; University of Kiel, Aschauhof, Eckernförde-Altenhof, 24340, Germany; Indonesian Pediatric Society, East Nusa Tenggara Branch, Kupang-East Nusa Tenggara, Kupang, 85351, Indonesia; Indonesian Medical Association Branch, Kupang, 85351, Indonesia; DDS PPDGS Konservasi Gigi FKG UGM, Jl. Sekip Utara, Sumatra, Medan, 20153, Indonesia; Faculty of Medicine, Nusa Cendana University, Kupang, 85351, Indonesia; Department of Child Health, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada-Dr, Sardjito General Hospital, Yogyakarta, 55281, Indonesia; Department of Child Health, Faculty of Medicine, Universitas Indonesia-Ciptomangunkusumo Hospital, Jakarta, 10430, Indonesia |
Scheffler, C., Institute of Biochemistry and Biology, Human Biology, University of Potsdam, Potsdam, 14469, Germany; Hermanussen, M., University of Kiel, Aschauhof, Eckernförde-Altenhof, 24340, Germany; Soegianto, S.D.P., Indonesian Pediatric Society, East Nusa Tenggara Branch, Kupang-East Nusa Tenggara, Kupang, 85351, Indonesia; Homalessy, A.V., Indonesian Medical Association Branch, Kupang, 85351, Indonesia; Touw, S.Y., Indonesian Medical Association Branch, Kupang, 85351, Indonesia; Angi, S.I., DDS PPDGS Konservasi Gigi FKG UGM, Jl. Sekip Utara, Sumatra, Medan, 20153, Indonesia; Ariyani, Q.S., Indonesian Medical Association Branch, Kupang, 85351, Indonesia; Suryanto, T., Indonesian Pediatric Society, East Nusa Tenggara Branch, Kupang-East Nusa Tenggara, Kupang, 85351, Indonesia; Matulessy, G.K.I., Indonesian Medical Association Branch, Kupang, 85351, Indonesia; Fransiskus, T., Indonesian Pediatric Society, East Nusa Tenggara Branch, Kupang-East Nusa Tenggara, Kupang, 85351, Indonesia; Safira, A.V.C., Indonesian Medical Association Branch, Kupang, 85351, Indonesia; Puteri, M.N., Indonesian Medical Association Branch, Kupang, 85351, Indonesia; Rahmani, R., Indonesian Medical Association Branch, Kupang, 85351, Indonesia; Ndaparoka, D.N., Indonesian Medical Association Branch, Kupang, 85351, Indonesia; Payong, M.K.E., Indonesian Medical Association Branch, Kupang, 85351, Indonesia; Indrajati, Y.D., DDS PPDGS Konservasi Gigi FKG UGM, Jl. Sekip Utara, Sumatra, Medan, 20153, Indonesia; Purba, R.K.H., Faculty of Medicine, Nusa Cendana University, Kupang, 85351, Indonesia; Manubulu, R.M., Indonesian Pediatric Society, East Nusa Tenggara Branch, Kupang-East Nusa Tenggara, Kupang, 85351, Indonesia; Julia, M., Department of Child Health, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada-Dr, Sardjito General Hospital, Yogyakarta, 55281, Indonesia; Pulungan, A.B., Department of Child Health, Faculty of Medicine, Universitas Indonesia-Ciptomangunkusumo Hospital, Jakarta, 10430, Indonesia |
Socially, economically, politically and emotionally (SEPE) disadvantaged children are shorter than children from affluent background. In view of previous work on the lack of association between nutrition and child growth, we performed a study in urban schoolchildren. We measured 723 children (5.83 to 13.83 years); Kupang, Indonesia; three schools with different social back-ground. We investigated anthropometric data, clinical signs of malnutrition, physical fitness, parental education, and household equipment. Subjective self-confidence was assessed by the MacArthur test. The prevalence of stunting was between 8.5% and 46.8%. Clinical signs of under-or malnutrition were absent even in the most underprivileged children. There was no delay in tooth erup-tion. Underprivileged children are physically fitter than the wealthy. The correlation between height and state of nutrition (BMI_SDS, skinfold_SDS, MUAC_SDS) ranged between r = 0.69 (p < 0.01) and r = 0.43 (p < 0.01) in private school children, and between r = 0.07 (ns) and r = 0.32 (p < 0.01) in the underprivileged children. Maternal education interacted with height in affluent (r = 0.20, p < 0.01) and in underprivileged children (r = 0.20, p < 0.01). The shortness of SEPE disadvantaged children was not associated with anthropometric and clinical signs of malnutrition, nor with delay in physical development. Stunting is a complex phenomenon and may be considered a synonym of social disadvantage and poor parental education. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Economic; Political and emotional factors on growth; Social; Stunting |
child; cross-sectional study; growth disorder; human; Indonesia; malnutrition; nutritional status; prevalence; Child; Cross-Sectional Studies; Growth Disorders; Humans; Indonesia; Malnutrition; Nutritional Status; Prevalence |
MDPI AG |
16617827 |
|
33540885 |
Article |
Q2 |
747 |
6560 |
|
|
585 |
Silitonga P., Bustamam A., Muradi H., Mangunwardoyo W., Dewi B.E. |
57219406661;36815737800;57188977950;24544449900;24076058600; |
Comparison of dengue predictive models developed using artificial neural network and discriminant analysis with small dataset |
2021 |
Applied Sciences (Switzerland) |
11 |
3 |
943 |
1 |
16 |
|
3 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099695109&doi=10.3390%2fapp11030943&partnerID=40&md5=3a9bba4cf9ba9dacfef04d7349c81f4b |
Department of Mathematics, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Kampus Baru UI, Depok, 16424, Indonesia; Department of Mathematics, Faculty of Science and Information Technology, Institut Sains dan Teknologi Nasional, Jl.Moh Kahfi II Srengseng Sawah Jagakarsa, Jakarta Selatan, 12640, Indonesia; Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Kampus Baru UI, Depok, 16424, Indonesia; Department of Microbiology, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no. 5, Kota Jakarta Pusat, Daerah Khusus Ibu Kota Jakarta, 10430, Indonesia |
Silitonga, P., Department of Mathematics, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Kampus Baru UI, Depok, 16424, Indonesia; Bustamam, A., Department of Mathematics, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Kampus Baru UI, Depok, 16424, Indonesia; Muradi, H., Department of Mathematics, Faculty of Science and Information Technology, Institut Sains dan Teknologi Nasional, Jl.Moh Kahfi II Srengseng Sawah Jagakarsa, Jakarta Selatan, 12640, Indonesia; Mangunwardoyo, W., Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Kampus Baru UI, Depok, 16424, Indonesia; Dewi, B.E., Department of Microbiology, Faculty of Medicine, Universitas Indonesia, Jl. Salemba Raya no. 5, Kota Jakarta Pusat, Daerah Khusus Ibu Kota Jakarta, 10430, Indonesia |
In Indonesia, dengue has become one of the hyperendemic diseases. Dengue consists of three clinical phases—febrile phase, critical phase, and recovery phase. Many patients have died in the critical phase due to the lack of proper and timely treatment. Therefore, we developed models that can predict the severity level of dengue based on the laboratory test results of the corresponding patients using Artificial Neural Network (ANN) and Discriminant Analysis (DA). In developing the models, we used a very small dataset. It is shown that ANN models developed using logistic and hyperbolic tangent activation function with 70% training data yielded the highest accuracy (90.91%), sensitivity (91.11%), and specificity (95.51%). This is the proposed model in this research. The proposed model will be able to help physicians in predicting the severity level of dengue patients before entering the critical phase. Furthermore, it will ease physicians in treating dengue patients early, so fatal cases or deaths can be avoided. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Artificial neural network; Dengue; Discriminant analysis |
|
MDPI AG |
20763417 |
|
|
Article |
Q2 |
435 |
11324 |
|
|
833 |
Kaligis F., Ismail R.I., Wiguna T., Prasetyo S., Indriatmi W., Gunardi H., Pandia V., Magdalena C.C. |
36604651700;55996895500;24367785700;56879108300;57189888041;56510252700;57208206604;57222744289; |
Mental health problems and needs among transitional-age youth in Indonesia |
2021 |
International Journal of Environmental Research and Public Health |
18 |
8 |
4046 |
|
|
|
1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103933053&doi=10.3390%2fijerph18084046&partnerID=40&md5=5f79eeea8b723a621bb8c21de80ea384 |
Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Faculty of Public Health, Universitas Indonesia, Depok, West Java, 16424, Indonesia; Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Dermatovenereology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Child Health, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Department of Psychiatry, Faculty of Medicine, Universitas Padjajaran, Bandung, West Java, 40115, Indonesia |
Kaligis, F., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Ismail, R.I., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Wiguna, T., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Prasetyo, S., Faculty of Public Health, Universitas Indonesia, Depok, West Java, 16424, Indonesia; Indriatmi, W., Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia, Department of Dermatovenereology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Gunardi, H., Department of Child Health, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia; Pandia, V., Department of Psychiatry, Faculty of Medicine, Universitas Padjajaran, Bandung, West Java, 40115, Indonesia; Magdalena, C.C., Department of Psychiatry, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia |
“Transitional-age youth” describes those whose ages range from 16–24 years old. In this phase, the youth face new challenges and new experiences which may increase the risk for having mental health problems, yet not very many seek help from mental health professionals. In Indone-sia, no data are available about mental health problems and the needs of transitional-age youth. This study explores common mental health problems experienced during this stage and assesses how they cope with problems and their expectations from health services. This was a cross-sectional study involving 393 Indonesians aged 16–24 years in May 2020. More than 90% of students had financial and academic difficulties and felt lonely. The most prevalent mental health problem among students was anxiety (95.4%). Most of the students, ranging from 90% to 96.4%, had positive coping strategies. However, around 50% of respondents reported self-harming and having suicidal thoughts. The results of subcategories analysis between ages and faculties were similar. Their most important expectations from mental health services included confidentiality (99.2%) and being wel-coming and friendly (99.2%). In conclusion, this study highlighted the most common problems tran-sitional-age youth experience in Indonesia. While some of them already knew how to deal with their problems, not all the participants had good coping mechanisms. Their healthcare expectations were also explored, thereby providing a useful background to revise and amend the current condi-tions. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Adolescence; Coping mechanisms; Health service expectation; Mental health needs; Mental health problems; Transitional-age youth |
academic performance; coping strategy; finance; health services; mental health; student; young population; adolescent; adult; age; anxiety; Article; automutilation; confidentiality; coping behavior; cross-sectional study; female; financial stress; health care access; health care need; health care quality; human; Indonesia; juvenile; loneliness; male; mental health; mental health service; prevalence; risk factor; school stress; suicidal ideation; transitional age youth; young adult; epidemiology; mental health service; Indonesia; Adolescent; Adult; Cross-Sectional Studies; Humans; Indonesia; Mental Health; Mental Health Services; Suicidal Ideation; Young Adult |
MDPI AG |
16617827 |
|
33921344 |
Article |
Q2 |
747 |
6560 |
|
|
901 |
Kadosh K.C., Muhardi L., Parikh P., Basso M., Mohamed H.J.J., Prawitasari T., Samuel F., Ma G., Geurts J.M.W. |
12243251700;57216729101;35269493300;57221482131;41861368100;57190686255;14421774000;57199673360;57197926057; |
Nutritional support of neurodevelopment and cognitive function in infants and young children—an update and novel insights |
2021 |
Nutrients |
13 |
1 |
199 |
1 |
26 |
|
4 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099415887&doi=10.3390%2fnu13010199&partnerID=40&md5=9754b1ffd94e454fc9ae27ba058537af |
School of Psychology, University of Surrey, Guildford, GU2 7XH, United Kingdom; FrieslandCampina AMEA, Singapore, 039190, Singapore; Department of General Psychology, University of Padova, Padova, 35131, Italy; Nutrition and Dietetics Programme, School of Health Sciences, Universiti Sains Malaysia, Kubang Kerian, 16150, Malaysia; Nutrition and Metabolic Diseases Working Group, Indonesian Pediatric Society, Jakarta, 10310, Indonesia; Department of Pediatrics, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusomo National Referral Hospital Jakarta, Jakarta, 10430, Indonesia; Department of Human Nutrition, University of Ibadan, Ibadan, 200284, Nigeria; Department of Nutrition and Food Hygiene, School of Public Health, Peking University, 38 Xue Yuan Road, Haidian District, Beijing, 10019, China; Laboratory of Toxicological Research and Risk assessment for Food Safety, Peking University, 38 Xue Yuan Road, Haidian District, Beijing, 100191, China; FrieslandCampina, Amersfoort, 3818 LE, Netherlands |
Kadosh, K.C., School of Psychology, University of Surrey, Guildford, GU2 7XH, United Kingdom; Muhardi, L., FrieslandCampina AMEA, Singapore, 039190, Singapore; Parikh, P., FrieslandCampina AMEA, Singapore, 039190, Singapore; Basso, M., School of Psychology, University of Surrey, Guildford, GU2 7XH, United Kingdom, Department of General Psychology, University of Padova, Padova, 35131, Italy; Mohamed, H.J.J., Nutrition and Dietetics Programme, School of Health Sciences, Universiti Sains Malaysia, Kubang Kerian, 16150, Malaysia; Prawitasari, T., Nutrition and Metabolic Diseases Working Group, Indonesian Pediatric Society, Jakarta, 10310, Indonesia, Department of Pediatrics, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusomo National Referral Hospital Jakarta, Jakarta, 10430, Indonesia; Samuel, F., Department of Human Nutrition, University of Ibadan, Ibadan, 200284, Nigeria; Ma, G., Department of Nutrition and Food Hygiene, School of Public Health, Peking University, 38 Xue Yuan Road, Haidian District, Beijing, 10019, China, Laboratory of Toxicological Research and Risk assessment for Food Safety, Peking University, 38 Xue Yuan Road, Haidian District, Beijing, 100191, China; Geurts, J.M.W., FrieslandCampina, Amersfoort, 3818 LE, Netherlands |
Proper nutrition is crucial for normal brain and neurocognitive development. Failure to optimize neurodevelopment early in life can have profound long-term implications for both mental health and quality of life. Although the first 1000 days of life represent the most critical period of neurodevelopment, the central and peripheral nervous systems continue to develop and change throughout life. All this time, development and functioning depend on many factors, including adequate nutrition. In this review, we outline the role of nutrients in cognitive, emotional, and neural development in infants and young children with special attention to the emerging roles of polar lipids and high quality (available) protein. Furthermore, we discuss the dynamic nature of the gut-brain axis and the importance of microbial diversity in relation to a variety of outcomes, including brain maturation/function and behavior are discussed. Finally, the promising therapeutic potential of psychobiotics to modify gut microbial ecology in order to improve mental well-being is presented. Here, we show that the individual contribution of nutrients, their interaction with other micro-and macronutrients and the way in which they are organized in the food matrix are of crucial importance for normal neurocognitive development. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
Brain; Childhood; Gut-brain axis; Kynurenine; Minerals; Neurodevelopment; Polar lipids; Polyunsaturated fatty acids; Prebiotics; Probiotics; Protein quality; Tryptophan; Tyrosine; Vitamins |
amino acid; branched chain amino acid; cyanocobalamin; iodine; iron; lipid; long chain fatty acid; mammalian target of rapamycin complex 1; phenylalanine; polar lipid; polyunsaturated fatty acid; prebiotic agent; probiotic agent; retinol; trace element; tryptophan; tyrosine; unclassified drug; vitamin D; zinc; fatty acid; kynurenine; mineral; brain development; child; cognition; emotion; human; infant; infant nutrition; intestine flora; macronutrient; nerve cell differentiation; nonhuman; nutritional support; protein intake; protein quality; Review; brain; cognitive aging; food; growth, development and aging; preschool child; quality of life; Brain; Child, Preschool; Cognition; Cognitive Aging; Emotions; Fatty Acids; Food; Gastrointestinal Microbiome; Humans; Infant; Kynurenine; Minerals; |
MDPI AG |
20726643 |
|
33435231 |
Review |
Q1 |
1418 |
2497 |
|
|