No records
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875 |
Lim M.A., Kurniawan A.A. |
57216039756;57222011563; |
Dreadful Consequences of Sarcopenia and Osteoporosis due to COVID-19 Containment |
2021 |
Geriatric Orthopaedic Surgery and Rehabilitation |
12 |
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3 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85101012807&doi=10.1177%2f2151459321992746&partnerID=40&md5=a0f3b09ec242d45be8f989650cec89a9 |
Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia; Eminence Sports Medicine and Human Performance Center, Jakarta, Indonesia; Department of Sports Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Lim, M.A., Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia, Eminence Sports Medicine and Human Performance Center, Jakarta, Indonesia; Kurniawan, A.A., Eminence Sports Medicine and Human Performance Center, Jakarta, Indonesia, Department of Sports Medicine, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
[No abstract available] |
Fragility Fractures; Geriatric Trauma; Metabolic Bone disorders; Osteoporosis; Sarcopenia |
vitamin D; absorptiometry; anthropometry; bone density; bone fragility; coronavirus disease 2019; dietary intake; dual energy X ray absorptiometry; fracture nonunion; fracture risk assessment; fragility fracture; health care personnel; hip fracture; Letter; lifestyle modification; musculoskeletal injury; osteomyelitis; osteopenia; osteoporosis; physical activity; physical performance; quality of life; sarcopenia; vitamin supplementation |
SAGE Publications Inc. |
21514585 |
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Letter |
- |
0 |
32716 |
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876 |
Sari I.P., Audindra S., Zhafira A.S., Rahma A.A., Syarira C.V., Wahdini S. |
57197543698;57222006228;57205515532;57222005612;57222010715;57203684068; |
Nutritional status of school-aged children with intestinal parasite infection in South Jakarta, Indonesia |
2021 |
Open Access Macedonian Journal of Medical Sciences |
9 |
E |
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95 |
100 |
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3 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100938719&doi=10.3889%2foamjms.2021.5711&partnerID=40&md5=1772780d39afba8ba66dd65e8997f0b4 |
Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Undergraduate Program in Medical Doctor, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
Sari, I.P., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Audindra, S., Undergraduate Program in Medical Doctor, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Zhafira, A.S., Undergraduate Program in Medical Doctor, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Rahma, A.A., Undergraduate Program in Medical Doctor, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Syarira, C.V., Undergraduate Program in Medical Doctor, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia; Wahdini, S., Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia |
BACKGROUND: The prevalence of intestinal parasitic infection still high in Indonesia and lead to nutritional disorder, especially in the school-aged children. AIM: This research conducted to find the association of intestinal parasitic infection to the nutritional status of the children. METHODS: This was a cross sectional study, conducted in January 2016 in one primary school in South Jakarta, Jakarta, Indonesia, by collecting the children’s stool from 1st to 5th grade. Direct examination of the stool was conducted in the Parasitology Department, Faculty of Medicine, Universitas Indonesia, by Lugol and eosin staining. Nutritional status categorized using BMI chart. Data were analyzed using Chi-square test, Statistical Product, and Service Solutions version 20. RESULTS: From the total 157 stool examined in the laboratory, there were 60 (38.2%) children positively infected with various kinds of intestinal parasites. Mostly the infection is caused by Blastocystis hominis, which infects 44 children (69.4%). The other infection is caused by Giardia lamblia (15.3%), Trichuris trichiura (1.4%), and hookworm (1.4%), and mixed infection of B. hominis and Escherichia coli (4.2%) and B. hominis with G. lamblia (4.2%). From the total of infected children, 17 children (28.3%) have BMI below 5th percentile, and it was considered as malnourished. Moreover, 67 uninfected children have normal nutritional status. Statistically, there is an association between intestinal parasitic infection and nutritional status in school-aged children in South Jakarta (P < 0.05). CONCLUSION: The incidence of intestinal parasitic infection in school-aged children is 38.2%. Moreover, 28.3% of the infected children were malnourished and it is suggested that children with intestinal parasite infection have low nutritional status. © 2021 Ika Puspa Sari, Sacha Audindra, Aqila S. Zhafira, Arin A. Rahma, Cut V. Syarira, Sri Wahdini. |
Malnourish; Parasitic Infection; Primary Schools; South Jakarta |
Article; Blastocystis hominis; body mass; child; cross-sectional study; disease association; Escherichia coli; feces analysis; female; Giardia intestinalis; human; Indonesia; intestine parasite; major clinical study; male; malnutrition; mixed infection; nutritional status; obesity; parasitosis; prevalence; primary school; questionnaire; seasonal variation; Trichuris trichiura; underweight |
Open Access Macedonian Journal of Medical Sciences |
18579655 |
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Article |
Q3 |
288 |
15252 |
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877 |
Negara J.D.K., Mudjianto S., Budikayanti A., Adhitya Nugraha P.P. |
57221389254;57193794731;57194713932;57221981778; |
The effect of gamma wave optimization and attention on hitting skills in softball |
2021 |
International Journal of Human Movement and Sports Sciences |
9 |
1 |
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103 |
109 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100846277&doi=10.13189%2fsaj.2021.090114&partnerID=40&md5=572b9a6bf2d4f86222486dfb5b12188a |
Department of Sport Education, Faculty of Sport Education and Health, Universitas Pendidikan Indonesia, Bandung, West Java, 40154, Indonesia; Department of Neurology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10440, Indonesia |
Negara, J.D.K., Department of Sport Education, Faculty of Sport Education and Health, Universitas Pendidikan Indonesia, Bandung, West Java, 40154, Indonesia; Mudjianto, S., Department of Sport Education, Faculty of Sport Education and Health, Universitas Pendidikan Indonesia, Bandung, West Java, 40154, Indonesia; Budikayanti, A., Department of Neurology, Faculty of Medicine, Universitas Indonesia, Jakarta, 10440, Indonesia; Adhitya Nugraha, P.P., Department of Sport Education, Faculty of Sport Education and Health, Universitas Pendidikan Indonesia, Bandung, West Java, 40154, Indonesia |
Hitting the ball is a complicated ability in softball academicie, because in appreciation to prioritizing movement skills, cognitive appearances additionally need to be investigated, one of which is attention. Meanwhile, going to hit the ball requires excellent attention for an individual student. Exhibiting gamma waves further influence arrangements of hitting performance. The objectives of this study were first, to determine the negative functional correlation between gamma brain waves and hitting skills, then second to know the positive functional correlation between attention and hitting skills and third to determine the effect of attention on increasing hitting skills. The method used in this research is an experimental method with a one-group pretest-posttest design research design. The sampling technique in this study was using a saturated sampling technique. This investigation amounted to 20 subjects, in the calculation of the Pearson product-moment correlation test using SPSS v.23. The first results collected were p-value 0.026 with an r square value of 0.25, so there is a significant negative functional correlation between gamma brain waves and hitting skills in softball learning of 25%. The second issue obtained p-value 0.017 with an r square value of 0.28, so there is a significant positive functional correlation between attention and hitting skills in softball learning by 28%. Furthermore, thirdly, the results obtained p-value 0.0001 between pre-test and post-test, with a significant increase in skills of 70.17%, so there is a significant influence between attention and hitting skills. © 2021 by authors, all rights reserved. |
Attention; Gamma Brain Waves; Hitting Skills; Softball Games |
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Horizon Research Publishing |
23814381 |
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Article |
Q4 |
132 |
25155 |
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878 |
Sitohang I.B.S., Rheza A.M., Sirait S.P., Fitri E.M., Suseno L.S. |
56734569200;57221927642;56426927400;57221929310;57202804092; |
Acne Vulgaris Mimicking Cutaneous Lupus Erythematosus in an Adolescent: Report of a Rare Case |
2021 |
Case Reports in Dermatology |
13 |
1 |
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69 |
74 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100667271&doi=10.1159%2f000511530&partnerID=40&md5=e670f0805c017b254cadf2cd24514e56 |
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia |
Sitohang, I.B.S., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Rheza, A.M., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Sirait, S.P., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Fitri, E.M., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Suseno, L.S., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia |
Acne vulgaris is a chronic and self-limiting disorder of the pilosebaceous unit which is primarily seen in adolescents. Acne vulgaris presents as polymorphic lesions, consisting of comedones, papules, pustules, cysts, nodules, scarring, and dyspigmentation. Acneiform presentation of cutaneous lupus erythematosus (CLE) is extremely rare. The presentation of CLE is notoriously diverse and often mimics a broad range of unrelated skin disorders. We present a case by referring to American College of Rheumatology (ACR) criteria for systemic lupus erythematosus (SLE); our patient's conditions did not meet any of the clinical criteria of the Systemic Lupus International Collaborating Clinics (SLICC) for SLE. Subsequent to thorough history-taking, physical examination, and laboratory evaluations, the diagnosis of acne vulgaris was established, and a diagnosis of CLE was excluded. As acneiform presentation of CLE is rare, we here present a case which resembled both acne vulgaris and CLE. We describe our experience in establishing the diagnosis of severe acne vulgaris accompanied by scars in a 12-year-old boy with a malar rash and scars on his frontal and malar area who had initially been misdiagnosed as having CLE. This unusual case highlights the broad spectrum of adolescent acne and the importance of clinical identification of the disease so that unnecessary workups might be avoided. © 2021 |
Adolescent; Cutaneous lupus erythematosus; Severe acne vulgaris |
2 hydroxyacid; antinuclear antibody; benzoyl peroxide; clindamycin; complement component C3; glycolic acid; retinoic acid; triamcinolone acetonide; acne; acne vulgaris; adolescent; Article; brain spongiosis; case report; child; clinical article; comedo; diagnostic error; epiluminescence microscopy; erythema; follow up; histopathology; human; human tissue; hyperpigmentation; hypertrophic scar; immunofluorescence; male; papule; physical examination; pustule; rash; scar; school child; skin biopsy; skin defect; skin lupus erythematosus; systemic lupus erythematosus; urinalysis |
S. Karger AG |
16626567 |
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Article |
Q3 |
338 |
13690 |
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879 |
Sitohang I.B.S., Parrol F., Fitri E.M., Nora R.L.D. |
56734569200;57221938934;57221929310;57216253806; |
Papulopustular and Ocular Rosacea with an Alleged Coincidence of Cutaneous Lupus Erythematosus: A Case Report |
2021 |
Case Reports in Dermatology |
13 |
1 |
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62 |
68 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100608017&doi=10.1159%2f000511495&partnerID=40&md5=d9521d968dd743848325d6f5df3a4bf9 |
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Sitohang, I.B.S., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Parrol, F., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Fitri, E.M., Department of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jalan Salemba No. 6, Jakarta, 10430, Indonesia; Nora, R.L.D., Department of Ophthalmology, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Rosacea is a chronic inflammatory skin disease characterized by central facial erythema with or without ocular involvement. It is often difficult to distinguish rosacea from other malar rashes, one of which is acute cutaneous lupus erythematosus (CLE), particularly when there is an increase in antinuclear antibody (ANA) level. We report the case of a 16-year old woman with facial erythematous plaque accompanied by papules and pustules, reddened eyes, and swollen eyelids since the last one year. Dermoscopic examination revealed telangiectasia, and skin scraping examination with 20% potassium hydroxide identified the presence of Demodex folliculorum. Further ocular examination also revealed blepharitis, dysfunction of Meibomian gland, cicatrix, and corneal neovascularization. The ANA titer was positive (1:320), while the anti-dsDNA was negative. The patient was treated according to standard treatment for rosacea. The patient showed a satisfactory response following 2 weeks of therapy. Signs of recurring red patches with papules, pustules, telangiectasia, and identification of D. folliculorum on skin scraping examination led to the diagnosis of papulopustular rosacea. A positive ANA test may also be present in other diseases, e.g. acute CLE. Therefore, the diagnosis of rosacea remains a challenge. Thorough observation and examination must be done in order to yield an accurate diagnosis of rosacea. © 2021 |
Case report; Cutaneous lupus erythematosus; Ocular rosacea; Papulopustular rosacea |
adapalene; antinuclear antibody; doxycycline; hydroxychloroquine; metronidazole; nitric oxide; potassium hydroxide; rheumatoid factor; abdominal pain; adolescent; anemia; arthralgia; Article; blepharitis; case report; clinical article; conjunctival hyperemia; conjunctivitis; cornea neovascularization; Demodex; Demodex folliculorum; dermatitis; dyspnea; eye examination; face erythema; female; food intake; hair loss; headache; histopathology; human; meibomian gland; oxidative stress; papule; periorbital edema; psoriasis; psoriatic arthritis; pustule; rosacea; scar; skin biopsy; skin defect; sun exposure; systemic lupus erythematosus; telangiectasia |
S. Karger AG |
16626567 |
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Article |
Q3 |
338 |
13690 |
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880 |
Putri T.P., Dewi I.A.T.K., Permata T.B.M., Nuryadi E., Kodrat H., Wibowo H., Louisa M., Gondhowiardjo S.A. |
57221919322;57221917792;57197808751;57197806814;57210639849;57217690943;41461551400;6508327402; |
A mini systematic review: Eucheuma cottonii, a red algae, as a radiosensitizer? |
2021 |
Tropical Journal of Natural Product Research |
5 |
1 |
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7 |
15 |
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100549316&doi=10.26538%2ftjnpr%2fv5i1.2&partnerID=40&md5=0849f73cb51c327672dca7dbaca3460f |
Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Diagnostic and Research Center, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Department of Pharmacology and Therapeutic, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Putri, T.P., Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Dewi, I.A.T.K., Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Permata, T.B.M., Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Nuryadi, E., Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Kodrat, H., Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Wibowo, H., Diagnostic and Research Center, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Louisa, M., Department of Pharmacology and Therapeutic, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Gondhowiardjo, S.A., Department of Radiation Oncology, Dr. Cipto Mangunkusumo National General Hospital, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia |
Radiosensitizers assist radiotherapy in providing greater tumor inactivation. Currently there is a search for natural radiosensitizer components which are expected to provide lesser side effects than chemical radiosensitizers. Eucheuma cottonii is a plant with antioxidant and anti-tumor effects. This review aims to search for the potential use of Eucheuma cottonii as a radiosensitizer. This is a mixed review study, where the main component is a systematic review and then followed by a narrative review. This review suggests that Eucheuma cottonii has the potential to become a radiosensitizer, by interfering with the cell cycle control mechanisms and reactivation of p53. Further research is needed to explore the synergistic effect of the combined use of radiotherapy and Eucheuma cottonii. © 2021 Putri et al. |
Anti-tumour; Eucheuma cottonii; Immunomodulator; Radiosensitizer |
antineoplastic agent; birc5 protein; carrageenan; CD4 antigen; CD8 antigen; checkpoint kinase 1; cyclin dependent kinase inhibitor; Eucheuma cottonii extract; gamma interferon; immunomodulating agent; interleukin 4; mouse double minute 2 homolog; plant extract; programmed death 1 ligand 1; protein bcl 2; protein p21; protein p53; radiosensitizing agent; survivin; unclassified drug; antiapoptotic activity; antineoplastic activity; antioxidant activity; antiproliferative activity; apoptosis; cancer cell line; cell cycle regulation; cytotoxicity; gene expression; human; IC50; in vitro study; in vivo study; Kappaphycus alvarezii; MTT assay; neoplasm; nonhuman; phagocytosis; protein expression; radiosensitization; randomized controlled trial (topic); Review; synergistic effect; systematic revie |
Faculty of Pharmacy, University of Benin |
26160684 |
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Review |
Q4 |
127 |
25832 |
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881 |
Harzif A., Hyaswicaksono P., Kurniawan R., Wiweko B. |
57191493435;57221907604;57196055951;43061741400; |
Heterotopic pregnancy: Diagnosis and pitfall in ultrasonography |
2021 |
Gynecology and Minimally Invasive Therapy |
10 |
1 |
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53 |
56 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100537776&doi=10.4103%2fGMIT.GMIT_92_19&partnerID=40&md5=ba933e51def94298b03a38705981ed87 |
Department of Obstetrics and Gynecology, Reproductive Immunology and Endocrinology Division, Faculty of Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, Indonesia; Department of Obstetrics and Gynecology, Faculty of Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jl. Diponegoro No. 71, Jakarta Pusat, 10340, Indonesia |
Harzif, A., Department of Obstetrics and Gynecology, Reproductive Immunology and Endocrinology Division, Faculty of Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, Indonesia; Hyaswicaksono, P., Department of Obstetrics and Gynecology, Faculty of Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jl. Diponegoro No. 71, Jakarta Pusat, 10340, Indonesia; Kurniawan, R., Department of Obstetrics and Gynecology, Faculty of Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jl. Diponegoro No. 71, Jakarta Pusat, 10340, Indonesia; Wiweko, B., Department of Obstetrics and Gynecology, Reproductive Immunology and Endocrinology Division, Faculty of Medicine, Dr. Cipto Mangunkusumo General Hospital, Universitas Indonesia, Jakarta, Indonesia |
Heterotopic pregnancy (HP) is the coexistence of extrauterine and intrauterine pregnancies. This case is rare, difficult to diagnose, and threatening if left untreated. Incidental rate is estimated 1 in 30,000 spontaneous pregnancies and higher in assisted reproductive techniques. HP is often missed because of the detection of intrauterine sacs; therefore, comprehensive and systematic ultrasonography (USG) is needed, especially when there is ectopic pregnancy suspicion or when there is free fluid in the pelvis. A 46-year nulligravida with 13-year primary infertility history underwent frozen embryo transfer process with positive beta-human chorionic gonadotropin 2 weeks after the procedure. Clinical pregnancy is expressed by gestational sac findings at 6-week gestation. Two weeks later, she complained of lower right abdominal pain accompanied by spots from the birth canal. USG showed intrauterine pregnancy and sac appropriate to 8-week gestation and adnexal mass accompanied by a ring of fire image. The patient underwent right salpingectomy, recovered well, and continued her pregnancy. In vitro fertilization is the main risk factor for multiple and ectopic pregnancies. Clinical manifestations are similar to pregnancy loss or ectopic pregnancy. Specific risk factor must be acknowledged by the physician prior initial examination to rule out HP. Transvaginal ultrasound is useful in making the diagnosis of HP, especially in early pregnancy. © 2021 Wolters Kluwer Medknow Publications. All rights reserved. |
Heterotopic; laparoscopy; ultrasound |
chorionic gonadotropin beta subunit; progesterone; abdominal pain; adnexa disease; adult; Article; case report; clinical article; ectopic pregnancy; embryo transfer; female; female infertility; first trimester pregnancy; gestational sac; human; in vitro fertilization; middle aged; priority journal; risk factor; salpingectomy; transvaginal echography; uterine adnexa |
Wolters Kluwer Medknow Publications |
22133070 |
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Article |
Q3 |
441 |
11202 |
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886 |
Susanto A.D., Yusril N., Zaini J., Nuwidya F. |
57190425587;57221834981;57221833355;57221834238; |
Comparison of serum benzo(a)pyrene diol epoxide - Protein adducts level between kretek cigarette smokers and nonsmokers and the related factors |
2021 |
Journal of Natural Science, Biology and Medicine |
12 |
1 |
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52 |
56 |
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2 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100352390&doi=10.4103%2fjnsbm.JNSBM_100_20&partnerID=40&md5=b1c54ebf4ef8452d480f9da52582dabe |
Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan Hospital, Jakarta, Indonesia; Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Susanto, A.D., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan Hospital, Jakarta, Indonesia; Yusril, N., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan Hospital, Jakarta, Indonesia; Zaini, J., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan Hospital, Jakarta, Indonesia; Nuwidya, F., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan Hospital, Jakarta, Indonesia, Department of Nutrition, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia |
Background: Benzopyrene is a carcinogenic agent found in cigarette smoke. Benzo(a)pyrene diol epoxide (BPDE) is one of the benzopyrene metabolites. In this study, we investigated the level of serum BPDE in kretek cigarette smokers compared to non-smokers. Methods: A cross-sectional study which involved 32 "healthy" kretek cigarette smokers and 32 "healthy" nonsmokers were conducted. We collected the blood sample and the serum BPDE level was assayed using enzyme-linked immunosorbent assay kit. The BPDE serum level in kretek cigarette smokers was compared to the level in nonsmokers. Results: A total of 32 kretek smokers and 32 controls underwent an examination of the BPDE-protein adducts level. In the kretek smokers group, 59.4% were aged over 45 years and 56.3% have a high educational background, while in the control group, 87.5% were aged under 45 years and 75% have high educational backgrounds. The level of BPDE-protein adducts in the kretek smokers subject was 12.15 (8.87-33.55) ng/ml and the levels in the control group were 11.4 (3.87-13.27) ng/ml, P = 0.004. The factors which influence the levels BDPE-protein adducts in smokers cigarettes, as determined by multivariate analysis, were sucking pattern (P = 0.002) and the degree of addiction (P = 0.047). Conclusion: The serum BPDE-protein adducts level was higher in smokers compared to nonsmokers, and the sucking pattern and degree of addiction are the influencing factors. © 2021 Wolters Kluwer Medknow Publications. All rights reserved. |
Benzo(a)pyrene diol epoxide-protein adducts; nonsmokers; smokers |
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Wolters Kluwer Medknow Publications |
09769668 |
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Article |
Q3 |
236 |
17374 |
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887 |
Arliny Y., Yunus F., Burhan E., Andarini S., Jusman S.W.A., Yunir E., Kekalih A., Soeroton A.Y., Nurwidya F. |
57221832635;57194486277;36058554600;8716259500;36518792100;36520254800;55633562200;57221832157;55221773800; |
Diagnostic predictors of active tuberculosis infection in diabetic patients with latent tuberculosis: A review on cathelicidin and 1,25-dihydroxyvitamin d3 |
2021 |
Journal of Natural Science, Biology and Medicine |
12 |
1 |
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117 |
123 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100332647&doi=10.4103%2fjnsbm.JNSBM_26_20&partnerID=40&md5=bcbc06659ad7db8063dc7a77d40a3bd0 |
Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Syiah Kuala, Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia; Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Indonesia, Persahabatan Hospital, Jakarta, Indonesia; Department of Biochemistry and Molecular Biology, Faculty of Medicine Universitas Indonesia, Indonesia; Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Community Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Division of Respirology and Critical Illness, Department of Internal Medicine, Faculty of Medicine Universitas Padjadjaran, Hasan Sadikin Hospital, Bandung, Indonesia |
Arliny, Y., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Syiah Kuala, Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia; Yunus, F., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Indonesia, Persahabatan Hospital, Jakarta, Indonesia; Burhan, E., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Syiah Kuala, Dr. Zainoel Abidin Hospital, Banda Aceh, Indonesia; Andarini, S., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Indonesia, Persahabatan Hospital, Jakarta, Indonesia; Jusman, S.W.A., Department of Biochemistry and Molecular Biology, Faculty of Medicine Universitas Indonesia, Indonesia; Yunir, E., Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Kekalih, A., Department of Community Medicine, Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Soeroton, A.Y., Division of Respirology and Critical Illness, Department of Internal Medicine, Faculty of Medicine Universitas Padjadjaran, Hasan Sadikin Hospital, Bandung, Indonesia; Nurwidya, F., Department of Pulmonology and Respiratory Medicine, Faculty of Medicine Universitas Indonesia, Persahabatan Hospital, Jakarta, Indonesia |
Background: Diabetes Mellitus has been identified as one of factors causing increased risks of latent TB infection. The roles of cathelicidin LL-37, 1.25(OH)2D3 as well as their correlation with specific IFN-γ in latent TB has not been extensively identified. Aims and Objectives: Our study was aimed to identify proportion of latent TB infection in patients with DM and to identify the role of cathelicidin, 1.25(OH)2D3, vitamin D and other clinical factors as predictors for active TB infection in diabetic patients with latent TB. Methods: Our study was conducted in 2 stages. The first-stage study was a cross-sectional study to identify the proportion of latent TB infection in patients with DM without any history of TB, which was continued with a case-control study to identify the roles of predictive biomarkers (cathelicidin LL-37, 25(OH) D3, 1.25(OH)2D3 and IFN-γ) as well as clinical predictive factors for active TB infection in diabetic patients with latent TB. Results: Out of 242 diabetic patients without any history of TB who underwent screening test for latent TB, there were 78 (33.2%) subjects with a diagnosis of latent TB and 1 subject was diagnosed with active TB. There was significant association on the level of cathelicidin LL-37 in DM patient with latent TB, active TB and without TB infection (23.49 ng/mL vs. 49.6 ng/mL vs. 10.46 ng/mL, P < 0,005). Almost all of subjects with DM showed low levels of vitamin D, most in subject with active TB (97%). There was no significant association between 1.25(OH)2D3 and 25(OH)D3 in DM patients with latent TB, active TB and without TB infection. There was a significant association on the levels of IFN-γ ((TB1 1.4 IU/mL vs. 0.03 IU/mL P < 0.005; TB2 1.4 IU/mL vs. 0.04 IU/mL P < 0.005) in DM subjects with latent TB and those without TB infection; however, no significant association was found in DM subjects with latent TB and active TB. History of smoking, HbA1C > 9.5% and cathelicidin LL-37 levels of > 30 ng/mL were predictors for latent TB into active TB in DM patients. Conclusion: Cathelicidin LL-37 can serve as a biomarker of latent TB progressiveness in patients with DM. © 2021 Wolters Kluwer Medknow Publications. All rights reserved. |
1,25 (OH)2D3; cathelicidin; diabetes; latent tuberculosis infection; Vitamin D |
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Wolters Kluwer Medknow Publications |
09769668 |
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Article |
Q3 |
236 |
17374 |
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889 |
Irdam G.A., Sutojo B., Raharja P.A.R. |
57194729795;57218247988;57201013616; |
Risk Factors of Ureteral Stenosis in Kidney Transplant Recipients: A Retrospective Study in National Referral Hospital in Indonesia |
2021 |
Advances in Urology |
2021 |
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2410951 |
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1 |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85100218047&doi=10.1155%2f2021%2f2410951&partnerID=40&md5=8c80f4380c17c32aba39dc8572cc7807 |
Department of Urology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia |
Irdam, G.A., Department of Urology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia; Sutojo, B., Department of Urology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia; Raharja, P.A.R., Department of Urology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, 10430, Indonesia |
Ureteral stenosis is one of the most common urological complications following kidney transplantations. It is occurred in 2-10% of patients and poses a significant problem to the patients as it may lead to permanent damage to renal damage. Identification of risk factors is important to prevent the incidence of ureteral stenosis. Thus, we aim to determine the risk factors of ureteral stenosis in the Indonesian population. This is a retrospective analysis of 487 kidney transplant patients performed in Cipto Mangunkusumo Hospital between 2014 and 2018. We collected and compared donor and recipient demography data in recipients who developed ureteral stenosis and recipients who did not develop ureteral stenosis. Ureteral stenosis was defined as the presence of hydronephrosis from ultrasound and increased number of serum creatinine. The overall incidence of ureteral stenosis post-kidney transplantation in our center is 6.6% (32 from 487 patients) from January 2014 until June 2018. We found that older donor and recipient age more frequent in developing ureteral stenosis post-kidney transplantation (p < 0.001). We also found that donors with number of arteries more than 2 (p < 0.001) and prolonged warm ischemic time (p < 0.05) are more frequently to develop ureteral stenosis post-kidney transplantation. There is no association between type II diabetes mellitus and hypertension with ureteral stenosis in this study. Donor age, recipient age, donor number of arteries more than 2, and prolonged warm ischemia time are associated with ureteral stenosis after kidney transplantation. © 2021 Gampo A. Irdam et al. |
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creatinine; adolescent; adult; age; aged; allograft; Article; child; creatinine blood level; disease association; female; graft recipient; human; hydronephrosis; hypertension; Indonesia; ischemia time; kidney donor; kidney graft; kidney transplantation; major clinical study; male; medical history; neurogenic bladder; non insulin dependent diabetes mellitus; postoperative period; retrospective study; risk factor; ureter obstruction; warm ischemia time |
Hindawi Limited |
16876369 |
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Article |
Q1 |
1180 |
3392 |
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